CN116725895A - Collagen liquid and preparation method thereof - Google Patents
Collagen liquid and preparation method thereof Download PDFInfo
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- CN116725895A CN116725895A CN202310693828.9A CN202310693828A CN116725895A CN 116725895 A CN116725895 A CN 116725895A CN 202310693828 A CN202310693828 A CN 202310693828A CN 116725895 A CN116725895 A CN 116725895A
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- 108010035532 Collagen Proteins 0.000 title claims abstract description 125
- 229920001436 collagen Polymers 0.000 title claims abstract description 125
- 239000007788 liquid Substances 0.000 title claims abstract description 43
- 238000002360 preparation method Methods 0.000 title claims abstract description 16
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- 241000209140 Triticum Species 0.000 claims abstract description 47
- 235000021307 Triticum Nutrition 0.000 claims abstract description 47
- 239000000284 extract Substances 0.000 claims abstract description 40
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 32
- 241001506047 Tremella Species 0.000 claims abstract description 26
- 235000011399 aloe vera Nutrition 0.000 claims abstract description 24
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims abstract description 24
- 241001116389 Aloe Species 0.000 claims abstract description 23
- 235000003145 Hippophae rhamnoides Nutrition 0.000 claims abstract description 17
- 229920001285 xanthan gum Polymers 0.000 claims abstract description 17
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- 229940082509 xanthan gum Drugs 0.000 claims abstract description 17
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- 239000002537 cosmetic Substances 0.000 claims abstract description 9
- 241000229143 Hippophae Species 0.000 claims description 19
- 239000002994 raw material Substances 0.000 claims description 16
- 238000000034 method Methods 0.000 claims description 12
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- 229910021641 deionized water Inorganic materials 0.000 claims description 2
- 239000000463 material Substances 0.000 claims 2
- 230000003020 moisturizing effect Effects 0.000 abstract description 26
- 230000000694 effects Effects 0.000 abstract description 17
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- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 description 1
- 235000002961 Aloe barbadensis Nutrition 0.000 description 1
- 244000186892 Aloe vera Species 0.000 description 1
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- 229920001287 Chondroitin sulfate Polymers 0.000 description 1
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- 108091005804 Peptidases Proteins 0.000 description 1
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- 239000004365 Protease Substances 0.000 description 1
- 108010009736 Protein Hydrolysates Proteins 0.000 description 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
Abstract
The application relates to the technical field of cosmetics, and particularly discloses a collagen liquid and a preparation method thereof, wherein the collagen liquid comprises 15-30 parts of hydrolyzed collagen; 10-20 parts of hydrolyzed wheat protein; 3-8 parts of aloe juice; 1-5 parts of sea buckthorn extract; 40-60 parts of tremella extract; 2-3 parts of glycerol; 0.8-1.5 parts of xanthan gum; 30-60 parts of water. The collagen liquid has the effect of permanently moisturizing skin.
Description
Technical Field
The application relates to the technical field of cosmetics, in particular to collagen liquid and a preparation method thereof.
Background
Daily skin moisturization is important for skin care, and skin moisturization can delay skin aging and reduce or avoid skin series problems. It has been studied that the moisture content of healthy skin horny layer should be maintained at 10% -20%, because skin shows a state of being very smooth, tender and elastic when the moisture content of skin horny layer is increased, and the skin is dry, rough, red, even chapped, etc. when the moisture content is less than 10%.
Collagen is extracted from animal skin, and the skin contains proteoglycan such as hyaluronic acid, chondroitin sulfate, etc. besides collagen, which contain a large amount of polar groups and are moisturizing factors. The collagen has the functions of purely natural moisturizing, whitening, wrinkle preventing, freckle removing and the like, and can be widely applied to cosmetic products.
At present, although the moisturizing effect of collagen is better, the moisturizing effect is not ideal enough, the moisturizing molecule permeability is not strong, the collagen cannot penetrate into the inner layer of the skin, the moisture is locked, and the lasting moisturizing effect cannot be achieved.
Disclosure of Invention
In order to achieve the effect of permanently moisturizing skin, the application provides a collagen liquid and a preparation method thereof.
The application provides a collagen liquid, which adopts the following technical scheme:
the collagen liquid comprises the following raw materials in parts by weight:
15-30 parts of hydrolyzed collagen;
10-20 parts of hydrolyzed wheat protein;
3-8 parts of aloe juice;
1-5 parts of sea buckthorn extract;
40-60 parts of tremella extract;
2-3 parts of glycerol;
0.8-1.5 parts of xanthan gum;
30-60 parts of water.
By adopting the technical scheme, the hydrolyzed collagen has good moisturizing and skin care effects, the collagen contains hydrophilic natural moisturizing factors, the triple helix structure can strongly lock moisture, so that the skin can be kept moist and tender at any time, the hydrolyzed collagen can directly permeate into the bottom layer of the skin, has good affinity with surrounding tissues, can assist cells to manufacture the collagen, supplements the collagen of the skin, and achieves the effects of making the skin healthy and recovering elasticity. The wheat protein hydrolysate is combined with hydrolyzed collagen and hydrolyzed wheat protein, so that the effect of lasting moisturizing is greatly improved, wheat contains rich high-quality protein, when the protein in the wheat is successfully hydrolyzed, the wheat protein is formed into a form which has smaller molecular mass and is easy to be absorbed and utilized by skin, the hydrolyzed small-molecule polypeptide contains a large number of hydrophilic groups, the wheat hydrolyzed protein can directly penetrate the skin to be absorbed through the carrier, the hydrolyzed collagen is cooperated with the hydrolyzed wheat protein, and the hydrolyzed collagen has stronger permeability to the skin as the carrier of the hydrolyzed wheat protein, and after the two proteins are organically combined and combined, the hydrolyzed collagen has better permeability to the skin, has better effect of supplementing the skin collagen, can enhance the moisturizing effect of the skin, and enables the skin to be healthy and elastic.
The aloe juice is a natural extract, contains various moisturizing components and nutritional components beneficial to human bodies, and can directly reach the deepest layer of skin due to strong permeability of the aloe juice on the basis of combining hydrolyzed collagen and hydrolyzed wheat protein, and the ultra-strong permeability of the aloe juice can lock water, carry micromolecular collagen to permeate into the skin, and recover the functions of the collagen, so that the water is locked. The sea buckthorn extract is rich in vitamins, can promote the absorption of collagen small molecules, and has stronger effects of resisting lipid peroxidation and scavenging free radicals. The moisturizing property of the xanthan gum is the same as that of the glycerol, the xanthan gum and the glycerol can be combined, moisture can be well absorbed, the skin dryness relieving effect is achieved, the xanthan gum has the moisturizing and moisturizing effects, the skin can be tightly locked with the moisture, a layer of protective natural barrier is generated on the surface layer of the skin, and the skin is not easy to be polluted by external environment.
Optionally, the collagen liquid comprises the following raw materials in parts by weight:
15-27 parts of hydrolyzed collagen;
10-15 parts of hydrolyzed wheat protein;
3-5 parts of aloe juice;
1-4 parts of sea buckthorn extract;
40-55 parts of tremella extract;
2-3 parts of glycerol;
0.8-1.5 parts of xanthan gum;
30-60 parts of water.
By adopting the technical scheme, the proportion of each component is optimized, so that the components exert the performance and achieve the synergistic effect at the same time, and the skin achieves the effects of lasting moisturizing.
Optionally, the molecular weight of the hydrolyzed wheat protein is 2000-3000Da.
By adopting the technical scheme, the wheat protein is prepared by taking protein extracted from wheat as a raw material, decomposing macromolecular plant protein into small molecules in a hydrolysis mode, and enabling small molecule polypeptides to be easily absorbed and have strong biological activity. The hydrolyzed wheat protein is easier to be absorbed by skin, has the effects of moisturizing, resisting oxidation, softening and refining skin, and increasing skin elasticity.
Optionally, the molecular weight of the hydrolyzed collagen is 3000-6000Da.
Through adopting above-mentioned technical scheme, the collagen that hydrolyzes is through collagen hydrolysis processing, and the relative molecular mass after the hydrolysis is less, and the solubility is good, is absorbed by the human body more easily, can also promote the absorption of skin to other proteins simultaneously to play the effect of tightening skin, and have fine moisturizing effect, can lock the moisture in the skin at a great extent and not lost.
Optionally, the hydrolyzed collagen is a powdery product prepared by taking animal collagen as a raw material and performing treatments such as purification and purification.
By adopting the technical scheme, the hydrolyzed collagen adopted by the application is prepared by taking the collagen in animal connective tissue as a raw material and hydrolyzing and refining the raw material under the strictly controlled condition, and the hydrolyzed animal protein has high nutritive value and excellent performance, is a good natural physiologically active substance, is easy to be absorbed and utilized by a human body, and has higher collagen content after purification and higher utilization rate by the human body.
Optionally, the water is deionized water for cosmetic production.
Through adopting above-mentioned technical scheme, in order to satisfy the requirement of cosmetics high stability and good performance, the inorganic ion in the water can produce impact to cosmetics formula stability, and the phenomenon of demulsification appears in standing a period, therefore the water that the cosmetics used needs to carry out purification treatment.
Optionally, the tremella extract is obtained by adding distilled water into fresh tremella, pulping, leaching, centrifuging to obtain clear liquid, and the tremella extract is obtained.
By adopting the technical scheme, the tremella extract mainly contains tremella polysaccharide, and the tremella polysaccharide can increase the water concentration on the surface of the skin to form an inward flow gradient to the skin; on the other hand, the hydrophobic barrier is formed to reduce volatilization of percutaneous moisture, so that moisture content on the surface of skin is increased, tremella polysaccharide, hydrolyzed collagen and hydrolyzed wheat protein act synergistically, skin water retention capacity is guaranteed, and tremella polysaccharide is an effective antioxidant and has a certain effect of resisting skin aging.
Optionally, the collagen liquid as described above is used in the production of a mask.
By adopting the technical scheme, the collagen liquid prepared by the application is applied to the cosmetic mask, on one hand, moisture is prevented from evaporating from the surface of skin, surrounding moisture can be absorbed, the moisture content of the stratum corneum of the skin is improved, hydrolyzed collagen and hydrolyzed wheat protein are matched for use, and the collagen liquid can be used as a carrier, and carries other components to be released from the collagen and permeate into the skin, so that the skin is fine and smooth.
In a second aspect, the application provides a preparation method of a collagen liquid, which adopts the following technical scheme:
a preparation method of collagen liquid comprises mixing hydrolyzed collagen and hydrolyzed wheat protein under stirring, standing for 2-3d, adding aloe juice, tremella extract, fructus Hippophae extract, xanthan gum, glycerol and water under stirring, and standing for 2-3d to obtain collagen liquid.
By adopting the technical scheme, the hydrolyzed collagen is combined with the hydrolyzed wheat protein firstly, and then is mixed with other components, the hydrolyzed protein can be used as a carrier, and the hydrolyzed protein and other components act synergistically, so that moisturizing micromolecules permeate into the inner layer of the skin, and the moisturizing effect is greatly improved.
Optionally, in the step of preparing the collagen liquid, the hydrolyzed collagen and the hydrolyzed wheat protein are mixed and then placed in a standing way, and the mixture is placed in a sterile space at the temperature of 5-15 ℃ for storage at the standing time.
By adopting the technical scheme, the collagen liquid can be stored at low temperature, can ensure that the contained protein micromolecules can continuously have activity, is not polluted by bacteria, and can be prepared into natural pollution-free collagen liquid.
Optionally, aloe juice, tremella extract, sea buckthorn extract, xanthan gum, glycerol and water are added in the preparation step of the collagen liquid, stirred, and then placed in an aseptic space at 0-10 ℃ for standing.
By adopting the technical scheme, the collagen liquid after the components are mixed is placed for a period of time at low temperature, the layering and emulsifying phenomena are avoided, the components can be kept stable, and the activity of the components is ensured.
In summary, the application has the following beneficial effects:
1. the application combines the hydrolyzed collagen and the hydrolyzed wheat protein, the hydrolyzed collagen and the hydrolyzed wheat protein cooperate, the hydrolyzed collagen has stronger permeability to the skin, the hydrolyzed collagen is used as a carrier of the hydrolyzed wheat protein, and the two proteins have better permeability to the skin after being organically combined and combined, have the function of supplementing the skin collagen, and can enhance the water-retaining effect of the skin.
2. The aloe juice is adopted, and on the basis of combining hydrolyzed collagen and hydrolyzed wheat protein, the aloe juice can directly reach the deepest layer of the skin due to strong permeability, and the ultra-strong permeability of the aloe juice can lock water, carry micromolecular collagen to permeate into the skin, and recover the functions of the collagen.
3. The sea buckthorn extract is rich in vitamins, can promote the absorption of collagen micromolecules, and has the effects of resisting lipid peroxidation and scavenging free radicals.
Detailed Description
The present application will be described in further detail with reference to examples and comparative examples.
The raw material sources are as follows: aloe vera juice, available from Shanghai sources as fresh food and beverage limited; sea buckthorn extract from the company of the western Antian Guangdong biotechnology Co; xanthan gum, glycerol, available from sienna-vain biotechnology limited; wheat protein was hydrolyzed and purchased from the western world biotechnology company, inc.
Examples
Example 1
A preparation method of collagen liquid comprises the following preparation steps:
firstly, cutting fresh pigskin, weighing 1.1kg of pigskin, adding 0.015kg of water under stirring, heating to 60 ℃, then adding 0.006kg of protease, stirring for reaction for 4 hours, separating, filtering, concentrating, and then performing spray drying to obtain hydrolyzed collagen.
Adding 50 times of distilled water into 0.5kg fresh tremella, pulping for 2min, taking out, leaching in water bath at 70deg.C for 3 hr, centrifuging at 5000r/min for 10min, and collecting supernatant to obtain tremella extract.
Mixing hydrolyzed collagen and hydrolyzed wheat protein under stirring to form a mixed solution, standing the mixed solution in a sterile environment at 10deg.C for 3 days, adding aloe juice, tremella extract, fructus Hippophae extract, xanthan gum, glycerol and water, stirring for 30min, and standing in a sterile environment at 5deg.C for 3 days to obtain collagen solution, wherein the molecular weight of hydrolyzed wheat protein is 2000Da and the molecular weight of hydrolyzed collagen is 5000Da.
Example 2
A preparation method of collagen liquid is different from that of the embodiment 1 in that hydrolyzed collagen and hydrolyzed wheat protein are stirred and mixed to form a mixed solution, the mixed solution is placed in an aseptic environment at 5 ℃ for 3 days, then aloe juice, tremella extract, sea buckthorn extract, xanthan gum, glycerol and water are added and stirred for 30 minutes, and then the mixed solution is placed in an aseptic environment at 0 ℃ for 3 days, so that the collagen liquid is obtained, wherein the molecular weight of the hydrolyzed wheat protein is 1000Da, and the molecular weight of the hydrolyzed collagen is 3000Da.
Example 3
A preparation method of collagen liquid is different from that of the embodiment 1 in that hydrolyzed collagen and hydrolyzed wheat protein are stirred and mixed to form a mixed solution, the mixed solution is placed in a sterile environment at 15 ℃ for 3 days, then aloe juice, tremella extract, sea buckthorn extract, xanthan gum, glycerol and water are added and stirred for 30 minutes, and then the mixed solution is placed in a sterile environment at 10 ℃ for 3 days, so that the collagen liquid is obtained, wherein the molecular weight of the hydrolyzed wheat protein is 3000Da, and the molecular weight of the hydrolyzed collagen is 6000Da.
The components of examples 1-3 and their corresponding parts by weight are shown in Table 1.
TABLE 1 raw materials and weights (kg) of the raw materials in examples 1 to 3
| Component (A) | Example 1 | Example 2 | Example 3 |
| Hydrolyzed collagen | 25 | 15 | 30 |
| Hydrolyzed wheat protein | 15 | 20 | 10 |
| Aloe juice | 5 | 8 | 3 |
| Sea buckthorn extract | 3 | 1 | 5 |
| Tremella extract | 50 | 40 | 60 |
| Glycerol | 2.5 | 3 | 2 |
| Xanthan gum | 1 | 0.8 | 1.5 |
| Water and its preparation method | 40 | 30 | 60 |
Example 4
A method for preparing collagen liquid is different from example 2 in that the molecular weight of the hydrolyzed collagen is 2000Da.
Example 5
A method for preparing collagen liquid is different from example 3 in that the molecular weight of the hydrolyzed collagen is 8000Da.
Example 6
A method for preparing collagen liquid is different from example 2 in that the molecular weight of hydrolyzed wheat protein is 1000Da.
Example 7
A method for preparing collagen liquid is different from example 3 in that the molecular weight of hydrolyzed wheat protein is 4000Da.
Example 8
A method for preparing collagen liquid is different from example 2 in that hydrolyzed collagen and hydrolyzed wheat protein are mixed and then left to stand, and the mixture is left to stand at room temperature and stored in a sterile space at 2 ℃.
Example 9
A method for preparing a collagen solution, which is different from example 3 in that hydrolyzed collagen and hydrolyzed wheat protein are mixed and then left to stand, and the mixture is left to stand at room temperature in a sterile space at 20 ℃.
Comparative example
Comparative example 1
A method for preparing a collagen liquid, which is different from example 1 in that the raw material does not include hydrolyzed collagen.
Comparative example 2
A collagen liquid preparation method is different from example 1 in that the raw material does not include hydrolyzed wheat protein.
Comparative example 3
A method for preparing collagen liquid is different from example 1 in that the raw material does not include aloe juice.
Comparative example 4
A preparation method of collagen liquid is different from that of example 1 in that the raw material does not include sea buckthorn extract.
Performance test
Detection method
Using the collagen solutions prepared in examples 1 to 9 and comparative examples 1 to 4 as samples, a tencel mask base cloth (available from Dongguan, new Zhongjie nonwoven products Co., ltd.) was put into a cup containing the collagen solution and immersed for 15 minutes to sufficiently absorb the collagen solution, thereby obtaining a moisturizing mask.
Skin moisture content MMV test 100 female volunteers aged between 25 and 40 years were selected, and all volunteers were randomly divided into 5 groups of 20 persons each, each group was a moisturizing facial mask obtained by soaking a tencel facial mask base fabric in a collagen solution using examples 1 to 9 and comparative examples 1 to 4, respectively. All volunteers washed their faces and were rubbed with dry facial tissues prior to starting the testPurified water, then allowed to sit still for 30min in an environment at a temperature of 22 ℃ ± 1 ℃ and a humidity of 50% ± 5%. Skin moisture content of each group was measured using a skin moisture meter (Corneometer 825), and the average value was recorded as MMV 0 . The application of the facial mask is started for 15min, the moisture content of each group of skin is tested respectively at 4h, 6h and 8h after the application, and the average value is recorded as MMV t Skin moisture content change Δmmv= (MMV t -MMV 0 )/MMV 0 100%, each of the test works of the test subjects was measured by the same tester, and the test results are shown in Table 2.
TABLE 2 Performance test results
The skin moisture loss TEWL test was performed by selecting 80 volunteers aged 20-40 years old, randomly dividing all volunteers into 8 groups of 10 persons each, using the moisturizing masks prepared in examples 1-9 and comparative examples 1-4, respectively, 1 time after cleaning the face every night, 15 minutes each time, and continuously using for one month, wherein other skin care products used by all volunteers are the same, and using a moisture loss test probe TewameterTM300 to test the moisture loss before and after use, and the results are shown in table 3.
TABLE 3 Performance test results
As can be seen from the combination of examples 1 and examples 4 to 7 and the combination of tables 2 to 3, the performance of example 1 is superior to that of examples 4 to 7, and the change of skin moisture content with time in MMV test of skin moisture content can be seen that collagen after hydrolysis is more easily absorbed by skin, and hydrolyzed collagen and hydrolyzed wheat protein having a larger molecular weight are less effective in moisturizing because they are less easily absorbed by skin. It can be seen from the combination of example 1 and comparative examples 1-2 and the combination of tables 2 and 3 that the comparative examples 1-2 are free of hydrolyzed collagen and hydrolyzed wheat protein, respectively, and that the performance of example 1 is superior to that of comparative examples 1-2, and thus it can be seen that both hydrolyzed collagen and hydrolyzed wheat protein are compounded, and that the skin moisture retention and the improvement effect are great, and that the skin moisture loss is greatly reduced by the combination of hydrolyzed collagen and hydrolyzed wheat protein in example 1, as can be seen from the variation of TEWL.
As can be seen from the combination of examples 1 and examples 8-9 and the combination of tables 2 and 3, the performance of example 1 is superior to that of examples 8-9, and the prepared collagen liquid is subjected to aseptic treatment, so that the collagen liquid is more stable, and no unqualified product appears in the use process.
It can be seen from the combination of examples 1 and comparative examples 3 to 4 and tables 2 and 3 that the performance of example 1 is superior to that of comparative examples 3 to 4, and that comparative example 3 is that no aloe juice is added, and that comparative example 4 is that no sea buckthorn extract is added, aloe juice further enhances the permeability of hydrolyzed protein, sea buckthorn extract is rich in a large amount of vitamins, and promotes the permeation of hydrolyzed collagen and hydrolyzed wheat protein in the inner layer of skin, so that the addition of aloe juice and sea buckthorn extract contributes to the absorption and retention of water of skin from the viewpoint of the change of water content and water loss, and thus greatly improves the moisturizing effect of skin.
The present embodiment is only for explanation of the present application and is not to be construed as limiting the present application, and modifications to the present embodiment, which may not creatively contribute to the present application as required by those skilled in the art after reading the present specification, are all protected by patent laws within the scope of claims of the present application.
Claims (10)
1. A collagen solution, characterized in that: the material comprises the following raw materials in parts by weight:
15-30 parts of hydrolyzed collagen;
10-20 parts of hydrolyzed wheat protein;
3-8 parts of aloe juice;
1-5 parts of sea buckthorn extract;
40-60 parts of tremella extract;
2-3 parts of glycerol;
0.8-1.5 parts of xanthan gum;
30-60 parts of water.
2. A collagen solution according to claim 1, wherein: the material comprises the following raw materials in parts by weight:
15-27 parts of hydrolyzed collagen;
10-15 parts of hydrolyzed wheat protein;
3-5 parts of aloe juice;
1-4 parts of sea buckthorn extract;
40-55 parts of tremella extract;
2-3 parts of glycerol;
0.8-1.5 parts of xanthan gum;
30-60 parts of water.
3. A collagen solution according to claim 1, wherein: the molecular weight of the hydrolyzed wheat protein is 1000-3000Da.
4. A collagen solution according to claim 1, wherein: the molecular weight of the hydrolyzed collagen is 3000-6000Da.
5. A collagen solution according to claim 1, wherein: the hydrolyzed collagen is a powdery product prepared by taking animal collagen as a raw material and performing treatments such as purification and the like.
6. A collagen solution according to claim 1, wherein: the water is deionized water used for cosmetic production.
7. A collagen solution according to claim 1, wherein: the tremella extract is prepared by adding distilled water into fresh tremella, pulping, leaching, centrifuging to obtain clear liquid, and the tremella extract is obtained.
8. Use of a collagen liquid according to any one of claims 1 to 7 in the manufacture of a mask.
9. A method for preparing a collagen liquid according to any one of claims 1 to 7, characterized in that: the method comprises the following steps:
mixing hydrolyzed collagen and hydrolyzed wheat protein under stirring, standing for 2-3d, standing at room temperature in 5-15deg.C aseptic space, adding aloe juice, tremella extract, fructus Hippophae extract, xanthan gum, glycerol and water, stirring, and standing for 2-3d to obtain collagen solution.
10. The method for preparing a collagen liquid according to claim 9, wherein: the preparation method of the collagen liquid comprises the steps of adding aloe juice, tremella extract, sea buckthorn extract, xanthan gum, glycerol and water, stirring, and standing in a sterile environment at 0-10 ℃.
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