CN116723818A - 对温度稳定的不含矿物油的油包水乳液 - Google Patents
对温度稳定的不含矿物油的油包水乳液 Download PDFInfo
- Publication number
- CN116723818A CN116723818A CN202280011125.7A CN202280011125A CN116723818A CN 116723818 A CN116723818 A CN 116723818A CN 202280011125 A CN202280011125 A CN 202280011125A CN 116723818 A CN116723818 A CN 116723818A
- Authority
- CN
- China
- Prior art keywords
- oil
- inci
- formulation contains
- emulsion according
- cosmetic water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000839 emulsion Substances 0.000 title claims abstract description 13
- 229910052500 inorganic mineral Inorganic materials 0.000 title description 2
- 239000011707 mineral Substances 0.000 title description 2
- 239000000203 mixture Substances 0.000 claims abstract description 70
- 238000009472 formulation Methods 0.000 claims abstract description 66
- OSCJHTSDLYVCQC-UHFFFAOYSA-N 2-ethylhexyl 4-[[4-[4-(tert-butylcarbamoyl)anilino]-6-[4-(2-ethylhexoxycarbonyl)anilino]-1,3,5-triazin-2-yl]amino]benzoate Chemical compound C1=CC(C(=O)OCC(CC)CCCC)=CC=C1NC1=NC(NC=2C=CC(=CC=2)C(=O)NC(C)(C)C)=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=N1 OSCJHTSDLYVCQC-UHFFFAOYSA-N 0.000 claims abstract description 38
- 239000002537 cosmetic Substances 0.000 claims abstract description 22
- 239000007762 w/o emulsion Substances 0.000 claims abstract description 20
- 239000004359 castor oil Substances 0.000 claims abstract description 12
- 235000019438 castor oil Nutrition 0.000 claims abstract description 12
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims abstract description 12
- 239000001993 wax Substances 0.000 claims abstract description 10
- DXGLGDHPHMLXJC-UHFFFAOYSA-N oxybenzone Chemical compound OC1=CC(OC)=CC=C1C(=O)C1=CC=CC=C1 DXGLGDHPHMLXJC-UHFFFAOYSA-N 0.000 claims abstract description 8
- -1 polyethylene Polymers 0.000 claims abstract description 8
- YBGZDTIWKVFICR-JLHYYAGUSA-N Octyl 4-methoxycinnamic acid Chemical compound CCCCC(CC)COC(=O)\C=C\C1=CC=C(OC)C=C1 YBGZDTIWKVFICR-JLHYYAGUSA-N 0.000 claims abstract description 7
- 239000002480 mineral oil Substances 0.000 claims abstract description 7
- 235000010446 mineral oil Nutrition 0.000 claims abstract description 7
- 229940116351 sebacate Drugs 0.000 claims abstract description 6
- CXMXRPHRNRROMY-UHFFFAOYSA-L sebacate(2-) Chemical compound [O-]C(=O)CCCCCCCCC([O-])=O CXMXRPHRNRROMY-UHFFFAOYSA-L 0.000 claims abstract description 6
- 229920000058 polyacrylate Polymers 0.000 claims abstract description 5
- HEOCBCNFKCOKBX-RELGSGGGSA-N (1s,2e,4r)-4,7,7-trimethyl-2-[(4-methylphenyl)methylidene]bicyclo[2.2.1]heptan-3-one Chemical compound C1=CC(C)=CC=C1\C=C/1C(=O)[C@]2(C)CC[C@H]\1C2(C)C HEOCBCNFKCOKBX-RELGSGGGSA-N 0.000 claims abstract description 4
- 229940100555 2-methyl-4-isothiazolin-3-one Drugs 0.000 claims abstract description 4
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims abstract description 4
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims abstract description 4
- 239000004698 Polyethylene Substances 0.000 claims abstract description 4
- 125000005250 alkyl acrylate group Chemical group 0.000 claims abstract description 4
- 229920001577 copolymer Polymers 0.000 claims abstract description 4
- 229920006037 cross link polymer Polymers 0.000 claims abstract description 4
- WSDISUOETYTPRL-UHFFFAOYSA-N dmdm hydantoin Chemical compound CC1(C)N(CO)C(=O)N(CO)C1=O WSDISUOETYTPRL-UHFFFAOYSA-N 0.000 claims abstract description 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims abstract description 4
- BEGLCMHJXHIJLR-UHFFFAOYSA-N methylisothiazolinone Chemical compound CN1SC=CC1=O BEGLCMHJXHIJLR-UHFFFAOYSA-N 0.000 claims abstract description 4
- 239000004200 microcrystalline wax Substances 0.000 claims abstract description 4
- 235000019808 microcrystalline wax Nutrition 0.000 claims abstract description 4
- GQEZCXVZFLOKMC-UHFFFAOYSA-N n-alpha-hexadecene Natural products CCCCCCCCCCCCCCC=C GQEZCXVZFLOKMC-UHFFFAOYSA-N 0.000 claims abstract description 4
- FMJSMJQBSVNSBF-UHFFFAOYSA-N octocrylene Chemical group C=1C=CC=CC=1C(=C(C#N)C(=O)OCC(CC)CCCC)C1=CC=CC=C1 FMJSMJQBSVNSBF-UHFFFAOYSA-N 0.000 claims abstract description 4
- 229960000601 octocrylene Drugs 0.000 claims abstract description 4
- 229960001173 oxybenzone Drugs 0.000 claims abstract description 4
- 239000012188 paraffin wax Substances 0.000 claims abstract description 4
- 235000019809 paraffin wax Nutrition 0.000 claims abstract description 4
- 235000019271 petrolatum Nutrition 0.000 claims abstract description 4
- 229920000573 polyethylene Polymers 0.000 claims abstract description 4
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims abstract description 4
- 239000012176 shellac wax Substances 0.000 claims abstract description 4
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims abstract description 3
- DHNRXBZYEKSXIM-UHFFFAOYSA-N chloromethylisothiazolinone Chemical compound CN1SC(Cl)=CC1=O DHNRXBZYEKSXIM-UHFFFAOYSA-N 0.000 claims abstract description 3
- AXIUTKTZNZMMSI-UHFFFAOYSA-N octan-3-yl 2-cyano-3,3-diphenylprop-2-enoate Chemical compound C=1C=CC=CC=1C(=C(C#N)C(=O)OC(CC)CCCCC)C1=CC=CC=C1 AXIUTKTZNZMMSI-UHFFFAOYSA-N 0.000 claims abstract description 3
- 229960001679 octinoxate Drugs 0.000 claims abstract description 3
- 239000003921 oil Substances 0.000 claims description 20
- 235000019198 oils Nutrition 0.000 claims description 18
- 235000015112 vegetable and seed oil Nutrition 0.000 claims description 15
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 12
- 235000020238 sunflower seed Nutrition 0.000 claims description 9
- 229920001223 polyethylene glycol Polymers 0.000 claims description 8
- 239000002202 Polyethylene glycol Substances 0.000 claims description 7
- 239000008168 almond oil Substances 0.000 claims description 7
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 claims description 6
- OYHQOLUKZRVURQ-HZJYTTRNSA-M 9-cis,12-cis-Octadecadienoate Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC([O-])=O OYHQOLUKZRVURQ-HZJYTTRNSA-M 0.000 claims description 5
- 150000002148 esters Chemical class 0.000 claims description 5
- 229940049918 linoleate Drugs 0.000 claims description 5
- 150000003626 triacylglycerols Chemical class 0.000 claims description 5
- 239000008158 vegetable oil Substances 0.000 claims description 5
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 claims description 4
- 235000019489 Almond oil Nutrition 0.000 claims description 4
- 235000018936 Vitellaria paradoxa Nutrition 0.000 claims description 4
- 241001135917 Vitellaria paradoxa Species 0.000 claims description 4
- 150000001875 compounds Chemical class 0.000 claims description 4
- 239000004302 potassium sorbate Substances 0.000 claims description 4
- 229940069338 potassium sorbate Drugs 0.000 claims description 4
- 235000010241 potassium sorbate Nutrition 0.000 claims description 4
- 229940057910 shea butter Drugs 0.000 claims description 4
- FLPJVCMIKUWSDR-UHFFFAOYSA-N 2-(4-formylphenoxy)acetamide Chemical compound NC(=O)COC1=CC=C(C=O)C=C1 FLPJVCMIKUWSDR-UHFFFAOYSA-N 0.000 claims description 3
- 244000144725 Amygdalus communis Species 0.000 claims description 3
- 235000011437 Amygdalus communis Nutrition 0.000 claims description 3
- 229940074979 cetyl palmitate Drugs 0.000 claims description 3
- XJFGDLJQUJQUEI-UHFFFAOYSA-N dodecyl decanoate dodecyl octanoate Chemical compound CCCCCCCCCCCCOC(=O)CCCCCCC.CCCCCCCCCCCCOC(=O)CCCCCCCCC XJFGDLJQUJQUEI-UHFFFAOYSA-N 0.000 claims description 3
- PXDJXZJSCPSGGI-UHFFFAOYSA-N hexadecanoic acid hexadecyl ester Natural products CCCCCCCCCCCCCCCCOC(=O)CCCCCCCCCCCCCCC PXDJXZJSCPSGGI-UHFFFAOYSA-N 0.000 claims description 3
- XUGNVMKQXJXZCD-UHFFFAOYSA-N isopropyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(C)C XUGNVMKQXJXZCD-UHFFFAOYSA-N 0.000 claims description 3
- 229910052943 magnesium sulfate Inorganic materials 0.000 claims description 3
- 235000019341 magnesium sulphate Nutrition 0.000 claims description 3
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 claims description 2
- 239000000539 dimer Substances 0.000 claims description 2
- 239000001509 sodium citrate Substances 0.000 claims description 2
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 2
- IPCSVZSSVZVIGE-UHFFFAOYSA-M hexadecanoate Chemical compound CCCCCCCCCCCCCCCC([O-])=O IPCSVZSSVZVIGE-UHFFFAOYSA-M 0.000 claims 1
- 150000002170 ethers Chemical class 0.000 abstract description 4
- 229920000151 polyglycol Polymers 0.000 abstract description 2
- 239000010695 polyglycol Substances 0.000 abstract description 2
- 229920001522 polyglycol ester Polymers 0.000 abstract description 2
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 9
- 239000004615 ingredient Substances 0.000 description 8
- 229940071160 cocoate Drugs 0.000 description 5
- 244000020551 Helianthus annuus Species 0.000 description 4
- 235000003222 Helianthus annuus Nutrition 0.000 description 4
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 description 4
- VVOAZFWZEDHOOU-UHFFFAOYSA-N magnolol Chemical compound OC1=CC=C(CC=C)C=C1C1=CC(CC=C)=CC=C1O VVOAZFWZEDHOOU-UHFFFAOYSA-N 0.000 description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 2
- YVLPJIGOMTXXLP-UHFFFAOYSA-N 15-cis-phytoene Chemical compound CC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CC=CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C YVLPJIGOMTXXLP-UHFFFAOYSA-N 0.000 description 2
- 239000005632 Capric acid (CAS 334-48-5) Substances 0.000 description 2
- 239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 description 2
- 235000017011 Mandorlo dulce Nutrition 0.000 description 2
- 244000076313 Mandorlo dulce Species 0.000 description 2
- FLIACVVOZYBSBS-UHFFFAOYSA-N Methyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC FLIACVVOZYBSBS-UHFFFAOYSA-N 0.000 description 2
- 235000019484 Rapeseed oil Nutrition 0.000 description 2
- UCMIRNVEIXFBKS-UHFFFAOYSA-N beta-alanine Chemical compound NCCC(O)=O UCMIRNVEIXFBKS-UHFFFAOYSA-N 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- CVSVTCORWBXHQV-UHFFFAOYSA-N creatine Chemical compound NC(=[NH2+])N(C)CC([O-])=O CVSVTCORWBXHQV-UHFFFAOYSA-N 0.000 description 2
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 2
- GHVNFZFCNZKVNT-UHFFFAOYSA-M decanoate Chemical compound CCCCCCCCCC([O-])=O GHVNFZFCNZKVNT-UHFFFAOYSA-M 0.000 description 2
- 125000002704 decyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 2
- PKPOVTYZGGYDIJ-UHFFFAOYSA-N dioctyl carbonate Chemical compound CCCCCCCCOC(=O)OCCCCCCCC PKPOVTYZGGYDIJ-UHFFFAOYSA-N 0.000 description 2
- NOPFSRXAKWQILS-UHFFFAOYSA-N docosan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCCCO NOPFSRXAKWQILS-UHFFFAOYSA-N 0.000 description 2
- 150000002191 fatty alcohols Chemical class 0.000 description 2
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 150000002334 glycols Chemical class 0.000 description 2
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 2
- 229940039346 isoamyl cocoate Drugs 0.000 description 2
- AGBQKNBQESQNJD-UHFFFAOYSA-N lipoic acid Chemical compound OC(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-N 0.000 description 2
- 239000012184 mineral wax Substances 0.000 description 2
- 230000003020 moisturizing effect Effects 0.000 description 2
- AOHAPDDBNAPPIN-UHFFFAOYSA-N myristicinic acid Natural products COC1=CC(C(O)=O)=CC2=C1OCO2 AOHAPDDBNAPPIN-UHFFFAOYSA-N 0.000 description 2
- WWZKQHOCKIZLMA-UHFFFAOYSA-M octanoate Chemical compound CCCCCCCC([O-])=O WWZKQHOCKIZLMA-UHFFFAOYSA-M 0.000 description 2
- 230000001953 sensory effect Effects 0.000 description 2
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 2
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 2
- HLZKNKRTKFSKGZ-UHFFFAOYSA-N tetradecan-1-ol Chemical compound CCCCCCCCCCCCCCO HLZKNKRTKFSKGZ-UHFFFAOYSA-N 0.000 description 2
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 description 2
- DCXXMTOCNZCJGO-UHFFFAOYSA-N tristearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCC DCXXMTOCNZCJGO-UHFFFAOYSA-N 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- KAZSKMJFUPEHHW-UHFFFAOYSA-N (2E)-3-[5-(1,1-dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hdyroxyphenyl)-2-propen-1-one Natural products COC1=CC(O)=C(C(C)(C)C=C)C=C1C=CC(=O)C1=CC=C(O)C=C1 KAZSKMJFUPEHHW-UHFFFAOYSA-N 0.000 description 1
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 description 1
- NKJOXAZJBOMXID-UHFFFAOYSA-N 1,1'-Oxybisoctane Chemical compound CCCCCCCCOCCCCCCCC NKJOXAZJBOMXID-UHFFFAOYSA-N 0.000 description 1
- YVLPJIGOMTXXLP-UUKUAVTLSA-N 15,15'-cis-Phytoene Natural products C(=C\C=C/C=C(\CC/C=C(\CC/C=C(\CC/C=C(\C)/C)/C)/C)/C)(\CC/C=C(\CC/C=C(\CC/C=C(\C)/C)/C)/C)/C YVLPJIGOMTXXLP-UUKUAVTLSA-N 0.000 description 1
- YVLPJIGOMTXXLP-BAHRDPFUSA-N 15Z-phytoene Natural products CC(=CCCC(=CCCC(=CCCC(=CC=C/C=C(C)/CCC=C(/C)CCC=C(/C)CCC=C(C)C)C)C)C)C YVLPJIGOMTXXLP-BAHRDPFUSA-N 0.000 description 1
- XDOFQFKRPWOURC-UHFFFAOYSA-N 16-methylheptadecanoic acid Chemical compound CC(C)CCCCCCCCCCCCCCC(O)=O XDOFQFKRPWOURC-UHFFFAOYSA-N 0.000 description 1
- PFPQMWRASYNLMZ-LGIMBNBCSA-N 2-(3,4-dihydroxyphenyl)-3-[(2s,3r,4r,5s,6r)-3,4-dihydroxy-5-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[[(2r,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-5,7-dihydroxychromen-4-one Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1OC[C@@H]1[C@@H](O[C@@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)[C@H](O)[C@@H](O)[C@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 PFPQMWRASYNLMZ-LGIMBNBCSA-N 0.000 description 1
- FICQFRCPSFCFBY-UHFFFAOYSA-N 2-[bis(methylsulfanyl)methylidene]propanedinitrile Chemical compound CSC(SC)=C(C#N)C#N FICQFRCPSFCFBY-UHFFFAOYSA-N 0.000 description 1
- MWKPHOIHTLQZIY-UHFFFAOYSA-N 2-hexyldecyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(CCCCCC)CCCCCCCC MWKPHOIHTLQZIY-UHFFFAOYSA-N 0.000 description 1
- FRRZVECXALBSFQ-UHFFFAOYSA-N 3-(chloromethyl)-1,2-thiazole 1-oxide Chemical compound ClCC=1C=CS(=O)N=1 FRRZVECXALBSFQ-UHFFFAOYSA-N 0.000 description 1
- NBMKEXTXPZXRSH-UHFFFAOYSA-N 3-ethylhexyl 3,3-diphenylprop-2-enoate Chemical compound C1(=CC=CC=C1)C(=CC(=O)OCCC(CCC)CC)C1=CC=CC=C1 NBMKEXTXPZXRSH-UHFFFAOYSA-N 0.000 description 1
- FVKRIDSRWFEQME-UHFFFAOYSA-N 3-methylbutyl dodecanoate Chemical compound CCCCCCCCCCCC(=O)OCCC(C)C FVKRIDSRWFEQME-UHFFFAOYSA-N 0.000 description 1
- 240000005528 Arctium lappa Species 0.000 description 1
- 235000003130 Arctium lappa Nutrition 0.000 description 1
- 235000008078 Arctium minus Nutrition 0.000 description 1
- 244000125300 Argania sideroxylon Species 0.000 description 1
- 235000016108 Argania sideroxylon Nutrition 0.000 description 1
- JMGZEFIQIZZSBH-UHFFFAOYSA-N Bioquercetin Natural products CC1OC(OCC(O)C2OC(OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)c(O)c5)C(O)C2O)C(O)C(O)C1O JMGZEFIQIZZSBH-UHFFFAOYSA-N 0.000 description 1
- QFOHBWFCKVYLES-UHFFFAOYSA-N Butylparaben Chemical class CCCCOC(=O)C1=CC=C(O)C=C1 QFOHBWFCKVYLES-UHFFFAOYSA-N 0.000 description 1
- QRYRORQUOLYVBU-VBKZILBWSA-N Carnosic acid Natural products CC([C@@H]1CC2)(C)CCC[C@]1(C(O)=O)C1=C2C=C(C(C)C)C(O)=C1O QRYRORQUOLYVBU-VBKZILBWSA-N 0.000 description 1
- 108010087806 Carnosine Proteins 0.000 description 1
- ACTIUHUUMQJHFO-UHFFFAOYSA-N Coenzym Q10 Natural products COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UHFFFAOYSA-N 0.000 description 1
- 235000000638 D-biotin Nutrition 0.000 description 1
- 239000011665 D-biotin Substances 0.000 description 1
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- IUCVKTHEUWACFB-UHFFFAOYSA-N Licochalcone A Natural products COC1=CC=C(C(C)(C)C=C)C=C1C=CC(=O)C1=CC=C(O)C=C1 IUCVKTHEUWACFB-UHFFFAOYSA-N 0.000 description 1
- KAZSKMJFUPEHHW-DHZHZOJOSA-N Licochalcone A Chemical compound COC1=CC(O)=C(C(C)(C)C=C)C=C1\C=C\C(=O)C1=CC=C(O)C=C1 KAZSKMJFUPEHHW-DHZHZOJOSA-N 0.000 description 1
- 235000018330 Macadamia integrifolia Nutrition 0.000 description 1
- 240000000912 Macadamia tetraphylla Species 0.000 description 1
- 235000003800 Macadamia tetraphylla Nutrition 0.000 description 1
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 description 1
- CQOVPNPJLQNMDC-UHFFFAOYSA-N N-beta-alanyl-L-histidine Natural products NCCC(=O)NC(C(O)=O)CC1=CN=CN1 CQOVPNPJLQNMDC-UHFFFAOYSA-N 0.000 description 1
- DJNTZVRUYMHBTD-UHFFFAOYSA-N Octyl octanoate Chemical compound CCCCCCCCOC(=O)CCCCCCC DJNTZVRUYMHBTD-UHFFFAOYSA-N 0.000 description 1
- 240000007817 Olea europaea Species 0.000 description 1
- 244000021150 Orbignya martiana Species 0.000 description 1
- 235000014643 Orbignya martiana Nutrition 0.000 description 1
- 206010063493 Premature ageing Diseases 0.000 description 1
- 208000032038 Premature aging Diseases 0.000 description 1
- 235000004443 Ricinus communis Nutrition 0.000 description 1
- 244000000231 Sesamum indicum Species 0.000 description 1
- 235000003434 Sesamum indicum Nutrition 0.000 description 1
- 244000272459 Silybum marianum Species 0.000 description 1
- 235000010841 Silybum marianum Nutrition 0.000 description 1
- 235000004433 Simmondsia californica Nutrition 0.000 description 1
- 244000044822 Simmondsia californica Species 0.000 description 1
- 235000021355 Stearic acid Nutrition 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 235000021302 avocado oil Nutrition 0.000 description 1
- 239000008163 avocado oil Substances 0.000 description 1
- 229940000635 beta-alanine Drugs 0.000 description 1
- 230000008827 biological function Effects 0.000 description 1
- 235000013868 candelilla wax Nutrition 0.000 description 1
- 239000004204 candelilla wax Substances 0.000 description 1
- 229940073532 candelilla wax Drugs 0.000 description 1
- 235000013869 carnauba wax Nutrition 0.000 description 1
- 239000004203 carnauba wax Substances 0.000 description 1
- 229960004203 carnitine Drugs 0.000 description 1
- 229940044199 carnosine Drugs 0.000 description 1
- CQOVPNPJLQNMDC-ZETCQYMHSA-N carnosine Chemical compound [NH3+]CCC(=O)N[C@H](C([O-])=O)CC1=CNC=N1 CQOVPNPJLQNMDC-ZETCQYMHSA-N 0.000 description 1
- 229940082500 cetostearyl alcohol Drugs 0.000 description 1
- 229960000541 cetyl alcohol Drugs 0.000 description 1
- 239000007979 citrate buffer Substances 0.000 description 1
- 229940069078 citric acid / sodium citrate Drugs 0.000 description 1
- 229940110456 cocoa butter Drugs 0.000 description 1
- 235000019868 cocoa butter Nutrition 0.000 description 1
- 239000003240 coconut oil Substances 0.000 description 1
- 235000019864 coconut oil Nutrition 0.000 description 1
- 229940110767 coenzyme Q10 Drugs 0.000 description 1
- 235000017471 coenzyme Q10 Nutrition 0.000 description 1
- ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 239000002385 cottonseed oil Substances 0.000 description 1
- 235000012343 cottonseed oil Nutrition 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 229960003624 creatine Drugs 0.000 description 1
- 239000006046 creatine Substances 0.000 description 1
- 229940109239 creatinine Drugs 0.000 description 1
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 1
- SASYSVUEVMOWPL-NXVVXOECSA-N decyl oleate Chemical compound CCCCCCCCCCOC(=O)CCCCCCC\C=C/CCCCCCCC SASYSVUEVMOWPL-NXVVXOECSA-N 0.000 description 1
- 229960000735 docosanol Drugs 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 235000008524 evening primrose extract Nutrition 0.000 description 1
- 239000010475 evening primrose oil Substances 0.000 description 1
- 229940089020 evening primrose oil Drugs 0.000 description 1
- 229930003935 flavonoid Natural products 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 235000019152 folic acid Nutrition 0.000 description 1
- 229960000304 folic acid Drugs 0.000 description 1
- 239000011724 folic acid Substances 0.000 description 1
- 229930182478 glucoside Natural products 0.000 description 1
- 125000005456 glyceride group Chemical group 0.000 description 1
- 229940074047 glyceryl cocoate Drugs 0.000 description 1
- 125000003976 glyceryl group Chemical group [H]C([*])([H])C(O[H])([H])C(O[H])([H])[H] 0.000 description 1
- 239000008169 grapeseed oil Substances 0.000 description 1
- 230000036074 healthy skin Effects 0.000 description 1
- 239000010460 hemp oil Substances 0.000 description 1
- IUJAMGNYPWYUPM-UHFFFAOYSA-N hentriacontane Chemical compound CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC IUJAMGNYPWYUPM-UHFFFAOYSA-N 0.000 description 1
- 229920002674 hyaluronan Polymers 0.000 description 1
- 229960003160 hyaluronic acid Drugs 0.000 description 1
- 239000008172 hydrogenated vegetable oil Substances 0.000 description 1
- 229940078565 isoamyl laurate Drugs 0.000 description 1
- CJWQYWQDLBZGPD-UHFFFAOYSA-N isoflavone Natural products C1=C(OC)C(OC)=CC(OC)=C1C1=COC2=C(C=CC(C)(C)O3)C3=C(OC)C=C2C1=O CJWQYWQDLBZGPD-UHFFFAOYSA-N 0.000 description 1
- 150000002515 isoflavone derivatives Chemical class 0.000 description 1
- 235000008696 isoflavones Nutrition 0.000 description 1
- 235000019136 lipoic acid Nutrition 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 235000009973 maize Nutrition 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 229940043348 myristyl alcohol Drugs 0.000 description 1
- 229940078812 myristyl myristate Drugs 0.000 description 1
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 description 1
- GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 229960002446 octanoic acid Drugs 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 150000002942 palmitic acid derivatives Chemical class 0.000 description 1
- 229940101267 panthenol Drugs 0.000 description 1
- 235000020957 pantothenol Nutrition 0.000 description 1
- 239000011619 pantothenol Substances 0.000 description 1
- 230000007903 penetration ability Effects 0.000 description 1
- 239000003209 petroleum derivative Substances 0.000 description 1
- 238000005191 phase separation Methods 0.000 description 1
- 235000011765 phytoene Nutrition 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 229940032094 squalane Drugs 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 229940012831 stearyl alcohol Drugs 0.000 description 1
- 229960003080 taurine Drugs 0.000 description 1
- DZKXJUASMGQEMA-UHFFFAOYSA-N tetradecyl tetradecanoate Chemical compound CCCCCCCCCCCCCCOC(=O)CCCCCCCCCCCCC DZKXJUASMGQEMA-UHFFFAOYSA-N 0.000 description 1
- OULAJFUGPPVRBK-UHFFFAOYSA-N tetratriacontyl alcohol Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO OULAJFUGPPVRBK-UHFFFAOYSA-N 0.000 description 1
- 229960002663 thioctic acid Drugs 0.000 description 1
- 229960001295 tocopherol Drugs 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 235000010384 tocopherol Nutrition 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- PJHKBYALYHRYSK-UHFFFAOYSA-N triheptanoin Chemical compound CCCCCCC(=O)OCC(OC(=O)CCCCCC)COC(=O)CCCCCC PJHKBYALYHRYSK-UHFFFAOYSA-N 0.000 description 1
- VLPFTAMPNXLGLX-UHFFFAOYSA-N trioctanoin Chemical compound CCCCCCCC(=O)OCC(OC(=O)CCCCCCC)COC(=O)CCCCCCC VLPFTAMPNXLGLX-UHFFFAOYSA-N 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
- A61K8/064—Water-in-oil emulsions, e.g. Water-in-silicone emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/23—Sulfur; Selenium; Tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/10—General cosmetic use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/30—Characterized by the absence of a particular group of ingredients
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Cosmetics (AREA)
Abstract
本发明涉及一种化妆用油包水乳液(W/O乳液)，含有：a)聚甘油‑4二异硬脂酸酯/聚羟基硬脂酸酯/癸二酸酯，以及b)氢化蓖麻油(INCI：氢化蓖麻油)，其中，制剂不含矿物油、石蜡、微晶蜡、紫胶蜡和聚乙烯蜡，不含聚丙烯酸酯、丙烯酸酯/C10‑30烷基丙烯酸酯交联聚合物、以及乙烯基吡咯烷酮/十六碳烯共聚物，且不含3‑(4‑甲基亚苄基)‑樟脑、2‑羟基‑4‑甲氧基二苯甲酮(INCI：氧苯酮)、4‑甲氧基肉桂酸‑2‑乙基己酯(INCI：甲氧基肉桂酸辛酯)、2‑氰基‑3,3‑二苯基丙烯酸乙基己酯(INCI：奥克立林)、对羟基苯甲酸酯(特别是对羟基苯甲酸甲酯、丙酯和丁酯)、甲基异噻唑啉酮、氯甲基异噻唑啉酮和DMDM乙内酰脲、聚乙二醇醚或聚乙二醇酯。
Description
技术领域
本发明涉及一种化妆用油包水乳液(W/O乳液)，其含有聚甘油-4二异硬脂酸酯/聚羟基硬脂酸酯/癸二酸酯，以及氢化蓖麻油(INCI：氢化蓖麻油)，其中，该制剂不含矿物油、石蜡、微晶蜡、紫胶蜡和聚乙烯蜡，不含聚丙烯酸酯、丙烯酸酯/C10-30烷基丙烯酸酯交联聚合物、以及乙烯基吡咯烷酮/十六碳烯共聚物，且不含3-(4-甲基亚苄基)-樟脑、2-羟基-4-甲氧基二苯甲酮(INCI：氧苯酮)、4-甲氧基肉桂酸-2-乙基己酯(INCI甲氧基肉桂酸辛酯)、2-氰基-3,3-二苯基丙烯酸乙基己酯(INCI：奥克立林)、对羟基苯甲酸酯(特别是对羟基苯甲酸甲酯、丙酯和丁酯)、甲基异噻唑啉酮、氯甲基异噻唑啉酮和DMDM乙内酰脲、聚乙二醇醚或聚乙二醇酯。
背景技术
看起来美丽且迷人的愿望是人类与生俱来的。尽管审美观会随着时间的推移而发生变化，但追求完美的外表一直是人们的目标。皮肤的状况和外观对于美丽且迷人的外表起着重要作用。
因此，为了使皮肤能够充分发挥其生物功能，需要定期进行清洁和护理。护肤品，通常是润肤霜、软膏或乳液，主要用于皮肤的加湿和补脂(Rückfettung)。通常，会向其中添加使皮肤恢复活力且例如防止和减少其提前老化(例如产生细纹、皱纹)的活性物质。
除了清洁和护理皮肤外，化妆品还具有美学功能。它们应当根据各自的文化观念“改善”用户的外在形象。因此，化妆品实现了一种心理社会功能，因为其提高了用户的(感观)吸引力。在该领域中最重要的是“装饰性”化妆品，其借助涂抹于皮肤上的色素改变用户的形象。然而，清洁产品和护理产品也间接地具有积极的影响，这是因为干净、健康的皮肤符合人类的审美观。
最近，“天然”化妆品的趋势日益凸显，其成分不应再来自石油产品或为化学合成。这种趋势现在与“纯素”产品的趋势相重叠。此外，寻找满足这些标准的替代成分给产品开发人员带来了特殊的挑战。这是因为，替换已知成分如矿物油、硅油、聚丙烯酸酯实际上总是以损害产品性能为代价。制剂会变得不稳定且感官上没有吸引力，例如当制剂分散在皮肤上并且缺乏渗入能力时，会令人明显感到不舒适。这些问题尤其会发生在最近再次变得越来越流行的油包水乳液(W/O乳液)中。例如，不含矿物油和矿物蜡且不含聚乙二醇醚或聚乙二醇酯(所谓的PEG衍生物)的W/O乳液倾向于变得更不稳定。在储存期较长的情况下，特别是W/O乳液在较高温度下，很快会以油和/或水分离的形式发生相分离，该相分离也不容易通过较高的乳化剂含量来补偿。
发明内容
因此，本发明的任务在于，开发一种不含矿物油和矿物蜡且不含聚乙二醇醚和聚乙二醇酯的W/O乳液，该W/O乳液甚至在较高温度也可稳定储存且不显现(或显著减少)油水分离。另外，W/O乳液应当可应用于各种油相组合物，即确保配方组合物的广泛应用，并具有感官吸引力(不油腻、不粘腻、易被皮肤吸收)。
出人意料地，该任务通过一种化妆用油包水乳液(W/O乳液)得到了解决，该乳液含有：
a)聚甘油-4二异硬脂酸酯/聚羟基硬脂酸酯/癸二酸酯，以及
b)氢化蓖麻油(INCI：氢化蓖麻油)，其中，制剂不含矿物油、石蜡、微晶蜡、紫胶蜡和聚乙烯蜡，不含聚丙烯酸酯、丙烯酸酯/C10-30烷基丙烯酸酯交联聚合物、以及乙烯基吡咯烷酮/十六碳烯共聚物，且不含3-(4-甲基亚苄基)-樟脑、2-羟基-4-甲氧基二苯甲酮(INCI：氧苯酮)、4-甲氧基肉桂酸-2-乙基己酯(INCI：甲氧基肉桂酸辛酯)、2-氰基-3,3-二苯基丙烯酸乙基己酯(INCI：奥克立林)、对羟基苯甲酸酯(特别是对羟基苯甲酸甲酯、丙酯和丁酯)、甲基异噻唑啉酮、氯甲基异噻唑啉酮和DMDM乙内酰脲、聚乙二醇醚或聚乙二醇酯。
尽管本领域技术人员已知DE 102017221672和DE 102018217130，但是这些文献并不能指明本发明的方向。
在此，根据本发明，优选制剂含有浓度为0.3至1.0重量％的氢化蓖麻油(INCI：氢化蓖麻油)，基于制剂的总重量。
根据本发明，本发明的有利的实施方式的特征在于，该制剂含有二异硬脂酰基聚甘油-3二聚亚油酸酯。
进而，根据本发明有利的是，该制剂含有浓度为0.2至2.0重量％的聚甘油-4二异硬脂酸酯/聚羟基硬脂酸酯/癸二酸酯，基于制剂的总重量，其中，根据本发明，优选浓度为0.5至1.5重量％，基于制剂的总重量。
如果根据本发明的W/O乳液含有二异硬脂酰基聚甘油-3二聚亚油酸酯，则根据本发明有利的是，该制剂含有浓度为0.2至2.0重量％的二异硬脂酰基聚甘油-3二聚亚油酸酯，基于制剂的总重量。特别优选浓度为0.5至1.5重量％。
此外，在本发明的意义上有利的是，该制剂含有一种或多种选自甘油三酯化合物的油。根据本发明有利的是，这些甘油三酯(甘油三酯的总量)的使用浓度为0.5至5.0重量％、特别优选为0.75至4.5重量％，基于制剂的总重量。
根据本发明，优选该制剂含有辛酸/癸酸椰油醇酯(INCI：椰油醇-辛酸酯/癸酸酯)。根据本发明，辛酸/癸酸椰油醇酯(INCI：椰油醇-辛酸酯/癸酸酯)有利的使用浓度为0.5至5.0重量％，基于制剂的总重量。特别优选浓度范围为0.75至4.5重量％，基于制剂的总重量。
进而，根据本发明，本发明的有利的实施方式的特征在于，该制剂含有一种或多种棕榈酸酯。
根据本发明尤其有利的是，该制剂含有棕榈酸鲸蜡酯和/或棕榈酸异丙酯。
如果该制剂含有棕榈酸鲸蜡酯，根据本发明有利的是，这些成分以0.2至1重量％的浓度添加，基于制剂的总重量。特别优选浓度为0.3至0.8重量％。
如果该制剂含有棕榈酸异丙酯，根据本发明有利的是，这些成分以1.0至15.0重量％的浓度添加，基于制剂的总重量。特别优选为3至12重量％。
此外，根据本发明有利的是，该制剂含有乳木果油和/或向日葵籽蜡(INCI：Helianthus Annuus Seed Cera)。
如果该制剂含有乳木果油，根据本发明有利的是，这些成分以0.5至3.0重量％的浓度添加，特别优选以0.75至2.5重量％的浓度添加，基于制剂的总重量。
如果该制剂含有向日葵籽蜡(INCI：Helianthus Annuus Seed Cera)，根据本发明有利的是，这些成分以0.1至0.75重量％的浓度添加、特别优选以0.1至0.5重量％的浓度添加，基于制剂的总重量。
进而，本发明的有利的实施方式的特征在于，该制剂含有一种或多种植物油。
根据本发明，优选该制剂含有一种或多种选自杏仁油(INCI：Prunus AmygdalusDulcis Oil(甜扁桃油))和/或向日葵籽油(INCI：Helianthus Annuus Seed Oil)化合物的油。
如果该制剂含有杏仁油(INCI：Prunus Amygdalus Dulcis Oil)，则根据本发明有利的是，这些成分以0.1至0.5重量％的浓度添加，基于制剂的总重量。
如果该制剂含有向日葵籽油(INCI：Helianthus Annuus Seed Oil)，根据本发明有利的是，这些成分以0.1至0.5重量％的浓度添加，基于制剂的总重量。
进而，根据本发明，本发明的有利的实施方式的特征在于，该制剂含有硫酸镁。根据本发明，优选硫酸镁以0.3至3.0重量％的浓度添加、优选以0.5至2.0重量％的浓度添加，基于制剂的总重量。
根据本发明，本发明的有利的实施方式的特征还在于，该制剂含有山梨酸钾。
如果该制剂含有山梨酸钾，则根据本发明有利的是，这些成分以0.05至0.5重量％的浓度添加、优选以0.075至0.30重量％的浓度添加，基于制剂的总重量。
此外，根据本发明，本发明的有利的实施方式的特征在于，该制剂含有柠檬酸和柠檬酸钠的混合物。
如果该制剂含有柠檬酸，则根据本发明有利的是，这些成分以0.05至0.25重量％的浓度添加，基于制剂的总重量。然后这些通过添加NaOH进行部分中和，形成柠檬酸/柠檬酸盐缓冲系统。
根据本发明，特别优选添加山梨酸钾与柠檬酸/柠檬酸钠的组合。
另外，根据本发明的W/O乳液可以含有其他成分。
例如，其他植物油可以选自鳄梨油、巴巴苏籽油、刺阿干树仁油、杏仁油、霍霍巴籽油、椰子油、水飞蓟籽油、月见草油、油橄榄果油、葡萄籽油、大麻籽油、植物油复合油(OlusOil)、植物油、草棉籽油、牛蒡籽油、澳洲坚果籽油、玉米胚芽油、甜扁桃油、蓖麻籽油、野大豆油、种间杂交向日葵籽油、芝麻籽油、油菜籽油中的化合物。
该制剂还可以含有一种或多种辛酸和/或癸酸的酯。
在这种情况下，根据本发明，优选辛酸和/或癸酸的酯选自辛酸甘油三酯/癸酸甘油三酯(INCI：辛酸/癸酸甘油三酯)、辛酸辛脂/癸酸辛脂(INCI：Caprylyl Caprylate/Caprate)、椰油酸甘油酯(INCI：Coco Glycerides)、椰油酸乙基己酯(INCI：Ethyl HexylCocoate)、椰油酸癸酯(INCI：Decyl Cocoate)、椰油酸异戊酯(INCI：Isoamyl Cocoate)、碳酸二辛酯(INCI：Dicaprylyl Carbonate)、椰油醇-辛酸酯(INCI：Coco-Caprylate)。
在本发明的意义上有利的是，该制剂含有蜡和/或脂肪醇。根据本发明，优选添加选自以下化合物的列表中的蜡或脂肪醇：
鲸蜡硬脂醇、鲸蜡醇、硬脂醇、棕榈酸甲酯、肉豆蔻酸肉豆蔻酯、氢化椰油酸甘油酯、肉豆蔻醇、山嵛醇、可可籽脂、氢化菜籽油、辛酸/癸酸/肉豆蔻酸/硬脂酸的甘油三酯、氢化植物油、巴西棕榈蜡、小烛树蜡、三硬脂酸甘油酯。
该制剂也可以含有一种或多种选自二辛基醚、油酸癸酯、辛基十二烷醇、角鲨烷、异硬脂酸三甘油酯、乳木果油乙酯、三庚酸甘油酯、硬脂酸己基癸酯、月桂酸异戊酯中的化合物的亲脂性成分。
根据本发明，本发明的有利的实施方式的特征在于，该制剂含有一种或多种选自α-硫辛酸、叶酸、八氢番茄红素、D-生物素、辅酶Q10、α-葡糖基芦丁、肉碱、肌肽、天然异黄酮、类黄酮、肌酸、肌酐、牛磺酸、β-丙氨酸、生育酚、泛醇、厚朴酚、和厚朴酚、甘油基葡糖苷、透明质酸和/或其盐和/或甘草查尔酮A中的化合物。
尤其根据本发明有利的是，该W/O乳液含有甘油。
具体实施方式
对比试验
制备了以下配制物并相互比较了它们的稳定性。
在刚制备结束后，未观察到差异。
将配制物在40℃储存。经储存30天后，配制物2中可以观察到轻微的油分离。这种不稳定性在进一步储存后变得愈加明显。配制物1在储存过程中未观察到不稳定性。
实施例
以下实施例旨在阐明本发明而非限制本发明。除非另有说明，所有量、比例和百分比均基于重量和总量或基于制剂的总重量。
Claims (15)
1.一种化妆用油包水乳液(W/O乳液)，含有：
a)聚甘油-4二异硬脂酸酯/聚羟基硬脂酸酯/癸二酸酯，以及
b)氢化蓖麻油(INCI：氢化蓖麻油)，其中，
制剂不含矿物油、石蜡、微晶蜡、紫胶蜡和聚乙烯蜡，不含聚丙烯酸酯、丙烯酸酯/C10-30烷基丙烯酸酯交联聚合物、以及乙烯基吡咯烷酮/十六碳烯共聚物，且不含3-(4-甲基亚苄基)-樟脑、2-羟基-4-甲氧基二苯甲酮(INCI：氧苯酮)、4-甲氧基肉桂酸-2-乙基己酯(INCI：甲氧基肉桂酸辛酯)、2-氰基-3,3-二苯基丙烯酸乙基己酯(INCI：奥克立林)、对羟基苯甲酸酯(特别是对羟基苯甲酸甲酯、丙酯和丁酯)、甲基异噻唑啉酮、氯甲基异噻唑啉酮和DMDM乙内酰脲、聚乙二醇醚或聚乙二醇酯。
2.根据权利要求1所述的化妆用油包水乳液，其特征在于，所述制剂含有浓度为0.3至1.0重量％的氢化蓖麻油(INCI：氢化蓖麻油)，基于制剂的总重量。
3.根据前述权利要求中任一项所述的化妆用油包水乳液，其特征在于，所述制剂含有二异硬脂酰基聚甘油-3二聚亚油酸酯。
4.根据前述权利要求中任一项所述的化妆用油包水乳液，其特征在于，所述制剂含有浓度为0.2至2.0重量％的聚甘油-4二异硬脂酸酯/聚羟基硬脂酸酯/癸二酸酯，基于制剂的总重量。
5.根据前述权利要求中任一项所述的化妆用油包水乳液，其特征在于，所述制剂含有浓度为0.2至2.0重量％的二异硬脂酰基聚甘油-3二聚亚油酸酯，基于制剂的总重量。
6.根据前述权利要求中任一项所述的化妆用油包水乳液，其特征在于，所述制剂含有一种或多种选自甘油三酯化合物的油。
7.根据前述权利要求中任一项所述的化妆用油包水乳液，其特征在于，所述制剂含有辛酸/癸酸椰油醇酯(INCI：椰油醇-辛酸酯/癸酸酯)。
8.根据前述权利要求中任一项所述的化妆用油包水乳液，其特征在于，所述制剂含有一种或多种棕榈酸酯。
9.根据前述权利要求中任一项所述的化妆用油包水乳液，其特征在于，所述制剂含有棕榈酸鲸蜡酯和/或棕榈酸异丙酯。
10.根据前述权利要求中任一项所述的化妆用油包水乳液，其特征在于，所述制剂含有乳木果油和/或向日葵籽蜡(INCI：向日葵籽蜡)。
11.根据前述权利要求中任一项所述的化妆用油包水乳液，其特征在于，所述制剂含有一种或多种植物油。
12.根据前述权利要求中任一项所述的化妆用油包水乳液，其特征在于，所述制剂含有一种或多种选自杏仁油(INCI：甜扁桃油)和/或向日葵籽油(INCI：向日葵籽油)化合物的油。
13.根据前述权利要求中任一项所述的化妆用油包水乳液，其特征在于，所述制剂含有硫酸镁。
14.根据前述权利要求中任一项所述的化妆用油包水乳液，其特征在于，所述制剂含有山梨酸钾。
15.根据前述权利要求中任一项所述的化妆用油包水乳液，其特征在于，所述制剂含有柠檬酸和柠檬酸钠的混合物。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102021200621.3 | 2021-01-25 | ||
| DE102021200621.3A DE102021200621A1 (de) | 2021-01-25 | 2021-01-25 | Temperaturstabile, mineralölfreie W/O-Emulsion |
| PCT/EP2022/050583 WO2022157055A1 (de) | 2021-01-25 | 2022-01-13 | Temperaturstabile, mineralölfreie w/o-emulsion |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116723818A true CN116723818A (zh) | 2023-09-08 |
Family
ID=80119003
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202280011125.7A Pending CN116723818A (zh) | 2021-01-25 | 2022-01-13 | 对温度稳定的不含矿物油的油包水乳液 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20240091118A1 (zh) |
| EP (1) | EP4281030A1 (zh) |
| CN (1) | CN116723818A (zh) |
| DE (1) | DE102021200621A1 (zh) |
| WO (1) | WO2022157055A1 (zh) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102012002950A1 (de) * | 2012-02-16 | 2013-08-22 | Beiersdorf Ag | Stabile Wasser in Öl Emulsionen mit HLB-ähnlichen Emulgatoren |
| US11865374B2 (en) * | 2017-11-15 | 2024-01-09 | Evonik Operations Gmbh | Functionalized polymers |
| DE102017221672A1 (de) | 2017-12-01 | 2019-06-06 | Beiersdorf Ag | Lipcare - neue mineralölfreie Stickgrundlage |
| DE102018217130A1 (de) | 2018-10-08 | 2020-04-09 | Beiersdorf Ag | Sonnenschutzmittel mit einer Kombination aus Wachsen und Cetylpalmitat |
-
2021
- 2021-01-25 DE DE102021200621.3A patent/DE102021200621A1/de not_active Withdrawn
-
2022
- 2022-01-13 WO PCT/EP2022/050583 patent/WO2022157055A1/de active Application Filing
- 2022-01-13 EP EP22701890.0A patent/EP4281030A1/de active Pending
- 2022-01-13 US US18/273,581 patent/US20240091118A1/en active Pending
- 2022-01-13 CN CN202280011125.7A patent/CN116723818A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE102021200621A1 (de) | 2022-07-28 |
| EP4281030A1 (de) | 2023-11-29 |
| WO2022157055A1 (de) | 2022-07-28 |
| US20240091118A1 (en) | 2024-03-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP2127635B1 (en) | Oil-in-water type emulsion composition | |
| US20110091400A1 (en) | Cosmetic emulsifier combination | |
| US20120189675A1 (en) | Skin External Preparations | |
| CN107438426B (zh) | 使用源自植物的天然表面活性剂的化妆料组合物 | |
| US20190083369A1 (en) | Two-phase make-up removal composition | |
| US10328006B2 (en) | W/O type emulsion and a premix for producing the same | |
| CN113727692B (zh) | 不含乳化剂的羟基酸凝胶霜组合物 | |
| JP2002518153A (ja) | 多量の水分を含む油中水エマルション型の流動性調製物 | |
| CN116723818A (zh) | 对温度稳定的不含矿物油的油包水乳液 | |
| KR102563508B1 (ko) | 고함량의 오일을 안정화시킨 수중유형 화장료 조성물 | |
| CN114269318A (zh) | 用于化妆品制剂的特别是天然的油替代品 | |
| CN113811279A (zh) | 不含丙烯酸酯和有机硅的化妆用o/w乳液 | |
| KR101812335B1 (ko) | 유화 조성물 | |
| CN114585349A (zh) | 用于化妆品制剂的特别是天然的油替代品 | |
| CN116723817A (zh) | 不含矿物油的化妆品w/o乳剂 | |
| EP4021381A1 (de) | Ölersatz für kosmetische zubereitungen | |
| WO2021220947A1 (ja) | 水中油型乳化組成物 | |
| CN114679905A (zh) | 不含丙烯酸酯和有机硅的化妆品o/w乳液 | |
| WO2023119260A1 (en) | Creamy hydrating cosmetic composition in a water release emulsion related applications | |
| JP2024027943A (ja) | クレンジング化粧料 | |
| DE102015218913A1 (de) | Wasserfreie kosmetische Zubereitung | |
| WO2014141948A1 (ja) | 乳液状化粧料組成物 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |