CN116688168A - Control method of moisture-proof bag for medical sterilization - Google Patents

Abstract

The invention relates to a moisture-proof control method for medical sterilization, belonging to the technical field of medical sterilization. The method adopts a pulse type vacuum sterilizer to sterilize the medical instrument bag wrapped by the Chinese medicinal powder or the non-woven fabric, and adopts compressed air at 110-160 ℃ to preheat the medical instrument bag or the Chinese medicinal powder to be sterilized before using saturated steam for sterilization. The invention can be used for sterilizing the instrument box/instrument bag wrapped by the non-woven fabric in the hospital, ensures that the non-woven fabric instrument box/instrument box has no condensed water after sterilization, reduces the drying time after sterilization and improves the sterilization efficiency. The method can also sterilize the bulk traditional Chinese medicine powder, heat the powder by compressed air before sterilization to make the articles reach a certain temperature, and then dehumidify the articles, wherein the traditional Chinese medicine powder is sterilized by heating by hot compressed air or steam, thereby realizing the moisture-proof effect, effectively preventing the traditional Chinese medicine powder from caking and realizing harmless operation.

Description

Control method of moisture-proof bag for medical sterilization

Technical Field

The invention relates to the technical field of sterilization, in particular to a sterilization moisture-proof bag control method suitable for medical instrument bags or traditional Chinese medicine powder.

Background

In the prior art, the sterilization of the medical instrument bag is carried out by using a pulsation vacuum sterilizer and adopting a pulsation vacuum method. The operation method is as follows: vacuumizing a sterilization chamber, then inputting saturated steam into the sterilization chamber, and raising the pressure to 0KPa; repeating the vacuumizing operation for 2-3 times, and then increasing the pressure to 0KPa; vacuumizing the sterilizing chamber again, inputting saturated steam into the sterilizing chamber, increasing the pressure to 90KPa, discharging the pressure of the sterilizing chamber to 20KPa, repeating the steps for 1-2 times until the pressure of the sterilizing chamber reaches 20KPa, inputting saturated steam into the sterilizing chamber, and increasing the pressure to 206KPa (corresponding to the temperature of 134 ℃); sterilizing at constant temperature for 6-8 min; exhausting the steam from the sterilizing chamber to 20KPa; vacuumizing the sterilizing chamber for 10-20 minutes (drying the sterilized matters); finally, sterile air is returned to the sterilizing chamber; and after the sterilization period is finished, the door can be opened to take out the objects. The sterilization chamber pressure, time profile of the prior art method is shown in fig. 4.

Most hospitals in China use cotton cloth for packaging medical instrument sterilization packaging materials before 2016. The cotton cloth has good water absorbability, and the sterilized instrument bag is not easy to generate visible condensed water. However, the method has the defects of short sterile shelf life of the sterilized instrument, high cost and reusability after cleaning and drying. According to the department of health WS310.1-2016, part 1 of the hospital disinfection supply center: most hospitals in China adopt non-woven fabrics for packaging medical instrument sterilization packaging materials.

The non-woven fabric packaging instrument package has the advantages that: the sterilized instrument has long sterile shelf life and low cost, and is not required to be cleaned and reused. But also has the following disadvantages: the non-woven fabrics have poor water absorption, and the sterilization in the prior art can cause condensed water in the instrument bag. Even if the instrument bag is subjected to short-time drying treatment after sterilization, the condensed water in the bag is difficult to completely dry, so that the sterilization cost is increased and the sterilization efficiency is reduced.

In the prior art, the sterilization process of the traditional Chinese medicine powder adopts cobalt irradiation sterilization: the cobalt irradiation sterilization technology is widely applied and developed in the foreign countries in the 30 s, and is introduced in the 70 s of China, so that the cobalt irradiation sterilization technology is applied to the disinsection and sterilization of traditional Chinese medicines and preparations. The cobalt 60 irradiation sterilization has the characteristics of strong radiation penetrability, no need of raising temperature and pressure and simple operation, so the method is quickly and widely used for sterilizing Chinese and western medicine preparations. Cobalt irradiation sterilization disadvantages: high cost, and the residual cobalt in the sterilized medicinal powder can cause cancer to human body.

Disclosure of Invention

The invention aims to solve the technical problems of the prior art, and provides a novel moisture-proof control method for medical sterilization, and the medical instrument package sterilization by adopting the method can realize drying and no condensed water after the sterilization of the instrument package packaged by non-woven fabrics, can realize the harmless moisture-proof sterilization of traditional Chinese medicine powder, reduce the sterilization process and improve the sterilization efficiency.

The technical problems to be solved by the invention are realized by the following technical proposal. The invention relates to a medical sterilization moisture-proof control method, which is characterized by comprising the following steps: the method adopts a pulse type vacuum sterilizer to sterilize the medical instrument bag wrapped by the Chinese medicinal powder or the non-woven fabric, and adopts compressed air at 110-160 ℃ to preheat the medical instrument bag or the Chinese medicinal powder to be sterilized before using saturated steam for sterilization. The traditional Chinese medicine powder can be bulk packed by a sterilizing tray during sterilization.

The invention relates to a medical sterilization moisture-proof control method, which further adopts the preferable technical scheme that: the pressure of the compressed air is 400Kpa to 700Kpa.

The invention relates to a medical sterilization moisture-proof control method, which further adopts the preferable technical scheme that: the method is suitable for controlling the sterilization moisture-proof bag of the medical instrument bag, and the preheating method is as follows: vacuumizing the sterilizing chamber to-60 KPa to-90 KPa, inputting compressed air at 110-160 ℃ into the sterilizing chamber, raising the pressure to 100 KPa-300 KPa, and keeping for 0-10 minutes; the method comprises the steps of circulating for N times, wherein N=1-5, vacuumizing an nth sterilizing chamber to-60 KPa to-90 KPa, inputting 110-160 ℃ compressed air into the sterilizing chamber again, increasing the pressure to 100 KPa-300 KPa, and keeping for 0-10 minutes; the temperature in the sterilized instrument bag reaches 55-80 ℃.

The invention relates to a medical sterilization moisture-proof control method, which further adopts the preferable technical scheme that: the method is suitable for controlling the sterilization moisture-proof bag of the medical instrument bag, and comprises the following specific steps:

preheating: vacuumizing the sterilizing chamber to-60 KPa to-90 KPa, inputting compressed air at 110-160 ℃ into the sterilizing chamber, raising the pressure to 100 KPa-300 KPa, and keeping for 0-10 minutes; the method is circulated for N times, wherein N=1 to 5, the nth sterilizing chamber is vacuumized to-60 KPa to-90 KPa, compressed air with the temperature of 110 to 160 ℃ is input into the sterilizing chamber again, the pressure is increased to 100KPa to 300KPa, and the sterilizing chamber is kept for 0 to 10 minutes; the temperature in the sterilized instrument package reaches 55-80 ℃;

and (3) sterilization: after preheating, vacuumizing the sterilizing chamber to-80 KPa to-95 KPa, and inputting saturated steam into the sterilizing chamber to raise the pressure to-60 KPa to 0KPa; vacuumizing the sterilizing chamber again to-80 KPa to-95 KPa, and then inputting saturated steam into the sterilizing chamber to raise the pressure to-60 KPa to 0KPa; vacuumizing the sterilizing chamber again to-80 KPa to-95 KPa, and inputting saturated steam into the sterilizing chamber to raise the pressure to 50KPa to 120KPa; the pressure of the exhaust steam of the sterilizing chamber is reduced to 10 KPa-40 KPa; again, the saturated steam pressure is input into the sterilizing chamber and is increased to 206KPa; sterilizing at constant temperature for 6-8 min;

and (3) drying: exhausting the steam from the sterilizing chamber to 20KPa; vacuumizing for 5-8 minutes to dry the sterilized material; sterile air is returned to the sterilization chamber; the sterilization cycle is ended.

The invention relates to a medical sterilization moisture-proof control method, which further adopts the preferable technical scheme that: the method comprises the following steps:

(1) Preheating: vacuumizing the sterilizing chamber to-80 KPa, inputting hot compressed air at 140 ℃ into the sterilizing chamber, raising the pressure to 265KPa, and keeping for 0-10 minutes; the method comprises the steps of circulating for N times, wherein N=1-5, vacuumizing an nth sterilizing chamber to-80 KPa, inputting compressed air at 140 ℃ into the sterilizing chamber again, raising the pressure to 265KPa, and keeping for 1-10 minutes; the temperature in the sterilized instrument package reaches 70 ℃;

(2) And (3) sterilization: after preheating, vacuumizing the sterilizing chamber to-90 KPa, and inputting saturated steam into the sterilizing chamber to raise the pressure to-47 KPa; vacuumizing the sterilizing chamber again to-90 KPa, and then inputting saturated steam into the sterilizing chamber to rise to-30 KPa; vacuumizing the sterilizing chamber again to-90 KPa, and inputting saturated steam into the sterilizing chamber to raise the pressure to 70KPa; the exhaust pressure of the sterilizing chamber is reduced to 20KPa; again, the saturated steam pressure is input into the sterilizing chamber and is increased to 206KPa; sterilizing at constant temperature for 6-8 min;

(3) And (3) drying: exhausting the steam from the sterilizing chamber to 20KPa; vacuumizing the sterilizing chamber for 5-8 minutes to dry the sterilized matters; sterile air is returned to the sterilization chamber; the sterilization cycle is ended.

The invention relates to a medical sterilization moisture-proof control method, which further adopts the preferable technical scheme that: the method is suitable for sterilizing and moisture-proof control of traditional Chinese medicine powder, and the preheating method is as follows: vacuumizing the sterilizing chamber to-60 KPa to-90 KPa, inputting 110-160 ℃ hot compressed air into the sterilizing chamber, raising the pressure to 100 KPa-300 KPa, and keeping for 0-10 minutes; the method comprises the steps of circulating for N times, wherein N=1-20, vacuumizing an nth sterilizing chamber to-60 KPa to-90 KPa, inputting 110-160 ℃ hot compressed air into the sterilizing chamber again, increasing the pressure to 100KPa to 300KPa, and keeping the pressure for 0-10 minutes; the temperature in the sterilized medicine powder reaches 40-50 ℃.

The invention relates to a medical sterilization moisture-proof control method, which further adopts the preferable technical scheme that: the method is suitable for sterilization and moisture-proof control of traditional Chinese medicine powder, and comprises the following specific steps:

(1) Preheating: vacuumizing the sterilizing chamber to-60 KPa to-90 KPa, inputting 110-160 ℃ hot compressed air into the sterilizing chamber, raising the pressure to 100 KPa-300 KPa, and keeping for 0-10 minutes; the method comprises the steps of circulating N times, namely, N=1 to 20, vacuumizing an nth sterilizing chamber to-60 KPa to-90 KPa, inputting 110 to 160 ℃ hot compressed air into the sterilizing chamber again, increasing the pressure to 100KPa to 300KPa, and keeping the pressure for 0 to 10 minutes; the temperature in the sterilized powder reaches 40-50 ℃;

(2) And (3) sterilization: vacuumizing the sterilizing chamber again to below-90 KPa for 40-60 min, and reducing the water content of the medicinal powder; inputting hot compressed air into the sterilizing chamber again, and raising the pressure to 100 KPa-300 KPa, and keeping for 0-10 minutes; the method comprises the steps of circulating for N times, wherein N=1-20, vacuumizing an nth sterilizing chamber to-60 KPa to-90 KPa, inputting 110-160 ℃ hot compressed air into the sterilizing chamber again, increasing the pressure to 100 KPa-300 KPa, and keeping for 0-10 minutes; the temperature in the sterilized powder reaches 100-110 ℃, the temperature is kept for 10-30 minutes, the internal chamber is exhausted to the door opening pressure, and the sterilization is finished.

The invention relates to a medical sterilization moisture-proof control method, which further adopts the preferable technical scheme that: the method comprises the following specific steps:

(1) Preheating: vacuumizing the sterilizing chamber to-80 KPa, inputting hot compressed air at 140 ℃ into the sterilizing chamber, raising the pressure to 265KPa, and keeping for 1-10 minutes; the method comprises the steps of circulating for N times, wherein N=1-20, vacuumizing an nth sterilizing chamber to-80 KPa, inputting hot compressed air at 140 ℃ into the sterilizing chamber again, raising the pressure to 265KPa, and keeping for 1-10 minutes; the temperature in the sterilized powder is up to 45 ℃;

(2) And (3) sterilization: vacuumizing the sterilizing chamber again to below-90 KPa for 40 min, and reducing water content of the medicinal powder; inputting hot compressed air into the sterilizing chamber again, and raising the pressure to 265KPa, and keeping for 1-10 minutes; the method comprises the steps of circulating for N times, wherein N=1-20, vacuumizing an nth sterilizing chamber to-80 KPa, inputting hot compressed air at 140 ℃ into the sterilizing chamber again, raising the pressure to 265KPa, and keeping for 1-10 minutes; the temperature in the sterilized powder reaches 100 ℃, the temperature is kept for 15 minutes, the internal chamber is exhausted to the door opening pressure, and the sterilization is finished.

The invention relates to a medical sterilization moisture-proof control method, which further adopts the preferable technical scheme that: the method is suitable for sterilization and moisture-proof control of traditional Chinese medicine powder, and comprises the following specific steps:

(1) Preheating: vacuumizing the sterilizing chamber to-60 KPa to-90 KPa, inputting 110-160 ℃ hot compressed air into the sterilizing chamber, raising the pressure to 100 KPa-300 KPa, and keeping for 0-10 minutes; the method comprises the steps of circulating N times, namely, N=1 to 20, vacuumizing an nth sterilizing chamber to-60 KPa to-90 KPa, inputting 110 to 160 ℃ hot compressed air into the sterilizing chamber again, increasing the pressure to 100KPa to 300KPa, and keeping the pressure for 0 to 10 minutes; the temperature in the sterilized traditional Chinese medicine powder reaches 40-50 ℃;

(2) And (3) sterilization: vacuumizing the sterilizing chamber again to below-90 KPa for 40-60 min, and reducing the water content of the medicinal powder; inputting hot compressed air into the sterilizing chamber again, increasing the pressure to 100 KPa-300 KPa, keeping for 0-10 minutes, circulating for N times, wherein N=1-20, vacuumizing the sterilizing chamber for the nth time to-60 KPa to-90 KPa, inputting hot compressed air at 110-160 ℃ into the sterilizing chamber again, increasing the pressure to 100 KPa-300 KPa, and keeping for 0-10 minutes; the temperature in the sterilized powder reaches 70-100 ℃; vacuumizing the sterilizing chamber again to-80 KPa to-95 KPa, and inputting saturated steam into the sterilizing chamber to raise the temperature of the material to 105-121 ℃ which is the set temperature for sterilization; sterilizing for 15-30 minutes at constant temperature; exhausting the steam from the sterilizing chamber to 20KPa; vacuumizing the sterilizing chamber for 5-8 minutes to dry the sterilized matters; sterile air is returned to the sterilization chamber; and (5) finishing sterilization.

The invention relates to a medical sterilization moisture-proof control method, which further adopts the preferable technical scheme that: the method comprises the following specific steps:

(1) Preheating: vacuumizing the sterilizing chamber to-80 KPa, inputting hot compressed air at 140 ℃ into the sterilizing chamber, raising the pressure to 265KPa, and keeping for 1-10 minutes; the method comprises the steps of circulating for N times, wherein N=1-20, vacuumizing an nth sterilizing chamber to-80 KPa, inputting hot compressed air at 140 ℃ into the sterilizing chamber again, raising the pressure to 265KPa, and keeping for 1-10 minutes; the temperature in the sterilized powder is up to 45 ℃;

(2) And (3) sterilization: vacuumizing the sterilizing chamber again to below-90 KPa for 40 min, and reducing water content of the medicinal powder; inputting hot compressed air into the sterilizing chamber again, and raising the pressure to 265KPa, and keeping for 1-10 minutes; the method comprises the steps of circulating for N times, wherein N=1-20, vacuumizing an nth sterilizing chamber to-80 KPa, inputting hot compressed air at 140 ℃ into the sterilizing chamber again, raising the pressure to 265KPa, and keeping for 1-10 minutes; the temperature in the sterilized powder reaches 80 ℃; vacuumizing the sterilizing chamber to-90 KPa again, and inputting saturated steam into the sterilizing chamber to raise the temperature of the material to 105-121 ℃ which is the set temperature for sterilization; sterilizing for 15-30 minutes at constant temperature; exhausting the steam from the sterilizing chamber to 20KPa; vacuumizing the sterilizing chamber for 5-8 minutes to dry the sterilized matters; sterile air is returned to the sterilization chamber; and (5) finishing sterilization.

Compared with the prior art, the invention has the following beneficial effects:

1. the invention can be used for sterilizing the instrument box/instrument bag wrapped by the non-woven fabric in a hospital, preheating by increasing the compressed air, and controlling the sterilization method at the same time, so that the non-woven fabric instrument box/instrument box is ensured to have no condensed water after sterilization, the drying time after sterilization is reduced, and the sterilization efficiency is improved.

2. The method can sterilize the bulk traditional Chinese medicine powder, heat the powder by compressed air before sterilization to make the articles reach a certain temperature, and then dehumidify the articles, wherein the traditional Chinese medicine powder is sterilized by heating by hot compressed air or steam, thereby realizing the moisture-proof effect, effectively preventing the traditional Chinese medicine powder from caking and realizing harmless operation.

Drawings

FIG. 1 is a graph of a sterilization profile for sterilizing a medical kit using the method of the present invention;

FIG. 2 is a graph showing a sterilization curve of a drug powder sterilized by the method of the present invention;

FIG. 3 is another sterilization chart of the sterilization of a drug powder using the method of the present invention;

FIG. 4 is a graph of a sterilization curve of a prior art method.

Detailed Description

Specific embodiments of the invention are described further below in order to facilitate a further understanding of the invention by those skilled in the art without limiting the scope of the claims thereto.

Example 1 referring to fig. 1, a medical sterilization moisture-proof control method is disclosed, wherein a pulse type vacuum sterilizer is used to sterilize a medical instrument bag wrapped by non-woven fabrics, and compressed air at 110 ℃ is used to preheat the medical instrument bag to be sterilized before the medical instrument bag is sterilized by saturated steam. The pressure of the compressed air was 400Kpa.

The method comprises the following specific steps:

preheating: vacuumizing the sterilizing chamber to-60 KPa, inputting 110 ℃ compressed air into the sterilizing chamber, raising the pressure to 100KPa, and keeping for 2 minutes; the process is circulated for 2 times, the sterilization chamber at the 2 nd time is vacuumized to-60 KPa, compressed air at 110 ℃ is input into the sterilization chamber again, the pressure is raised to 100KPa, and the sterilization chamber is kept for 2 minutes; the temperature in the sterilized instrument package reaches 55 ℃;

and (3) sterilization: after preheating, vacuumizing the sterilizing chamber to-80 KPa, and inputting saturated steam into the sterilizing chamber to-60 KPa; vacuumizing the sterilizing chamber again to-80 KPa, and then inputting saturated steam into the sterilizing chamber to raise the pressure to-60 KPa; vacuumizing the sterilizing chamber to-80 KPa again, and inputting saturated steam into the sterilizing chamber to raise the pressure to 50KPa; the exhaust pressure of the sterilizing chamber is reduced to 10KPa; again, the saturated steam pressure is input into the sterilizing chamber and is increased to 206KPa; sterilizing at constant temperature for 6 minutes;

and (3) drying: exhausting the steam from the sterilizing chamber to 20KPa; vacuumizing for 5 minutes to dry the sterilized matters; sterile air is returned to the sterilization chamber; the sterilization cycle is ended.

Example 2 referring to fig. 1, a medical sterilization moisture-proof control method is disclosed, wherein a pulse type vacuum sterilizer is used to sterilize a medical instrument bag wrapped by non-woven fabrics, and compressed air at 160 ℃ is used to preheat the medical instrument bag to be sterilized before the medical instrument bag is sterilized by saturated steam. The pressure of the compressed air was 700Kpa.

The method comprises the following specific steps:

preheating: vacuumizing the sterilizing chamber to-90 KPa, inputting 160 ℃ compressed air into the sterilizing chamber, raising the pressure to 300KPa, and keeping for 10 minutes; the method is circulated for 5 times, the 5 th sterilization chamber is vacuumized to-90 KPa, 160 ℃ compressed air is again input into the sterilization chamber, the pressure is increased to 300KPa, and the sterilization chamber is kept for 10 minutes; the temperature in the sterilized instrument package reaches 80 ℃;

and (3) sterilization: after preheating, vacuumizing the sterilizing chamber to-95 KPa, and inputting saturated steam into the sterilizing chamber to raise the pressure to 0KPa; vacuumizing the sterilizing chamber again to-95 KPa, and then inputting saturated steam into the sterilizing chamber to raise the pressure to 0KPa; vacuumizing the sterilizing chamber again to-95 KPa, and inputting saturated steam into the sterilizing chamber to raise the pressure to 120KPa; the exhaust pressure of the sterilizing chamber is reduced to 40KPa; again, the saturated steam pressure is input into the sterilizing chamber and is increased to 206KPa; sterilizing at constant temperature for 8 minutes;

and (3) drying: exhausting the steam from the sterilizing chamber to 20KPa; vacuumizing for 8 minutes to dry the sterilized matters; sterile air is returned to the sterilization chamber; the sterilization cycle is ended.

Example 3 referring to fig. 1, a medical sterilization moisture-proof control method adopts a pulse type vacuum sterilizer to sterilize a medical instrument pack wrapped by non-woven fabrics, and adopts compressed air at 140 ℃ to preheat the medical instrument pack to be sterilized before using saturated steam for sterilization. The pressure of the compressed air was 550Kpa.

The method comprises the following specific steps:

(1) Preheating: vacuumizing the sterilizing chamber to-80 KPa, inputting hot compressed air at 140 ℃ into the sterilizing chamber, raising the pressure to 265KPa, and keeping for 5 minutes; the circulation is carried out for 3 times, the sterilization chamber at the 3 rd time is vacuumized to-80 KPa, compressed air at 140 ℃ is again input into the sterilization chamber, the pressure is increased to 265KPa, and the sterilization chamber is kept for 5 minutes; the temperature in the sterilized instrument package reaches 70 ℃;

(2) And (3) sterilization: after preheating, vacuumizing the sterilizing chamber to-90 KPa, and inputting saturated steam into the sterilizing chamber to raise the pressure to-47 KPa; vacuumizing the sterilizing chamber again to-90 KPa, and then inputting saturated steam into the sterilizing chamber to rise to-30 KPa; vacuumizing the sterilizing chamber again to-90 KPa, and inputting saturated steam into the sterilizing chamber to raise the pressure to 70KPa; the exhaust pressure of the sterilizing chamber is reduced to 20KPa; again, the saturated steam pressure is input into the sterilizing chamber and is increased to 206KPa; sterilizing at constant temperature for 6-8 min;

(3) And (3) drying: exhausting the steam from the sterilizing chamber to 20KPa; vacuumizing the sterilizing chamber for 6 minutes to dry the sterilized matters; sterile air is returned to the sterilization chamber; the sterilization cycle is ended.

Example 4 referring to fig. 2, a method for controlling moisture prevention for medical sterilization, which uses a pulse type vacuum sterilizer to sterilize Chinese medicinal powder, and uses compressed air of 110 ℃ to preheat the Chinese medicinal powder before using saturated steam for sterilization. The pressure of the compressed air was 400Kpa.

The method is suitable for sterilization and moisture-proof control of traditional Chinese medicine powder, and comprises the following specific steps:

(1) Preheating: vacuumizing the sterilizing chamber to-60 KPa, inputting 110 ℃ hot compressed air into the sterilizing chamber, raising the pressure to 100KPa, and keeping for 1 minute; the method is circulated for 5 times, the 5 th sterilization chamber is vacuumized to-60 KPa, compressed air with 110 ℃ is again input into the sterilization chamber, the pressure is raised to 100KPa, and the sterilization chamber is kept for 1 minute; the temperature in the sterilized powder is up to 40 ℃;

(2) And (3) sterilization: vacuumizing the sterilizing chamber again to below-90 KPa for 40 min, and reducing water content of the medicinal powder; inputting hot compressed air into the sterilizing chamber again, increasing the pressure to 100KPa, and keeping for 1 minute; the method is circulated for 5 times, the 5 th sterilization chamber is vacuumized to-60 KPa, compressed air with 110 ℃ is again input into the sterilization chamber, the pressure is raised to 100KPa, and the sterilization chamber is kept for 1 minute; the temperature in the sterilized powder reaches 100 ℃, the powder is kept for 10 minutes, the inner chamber is exhausted to the pressure capable of opening the door, and the sterilization is finished.

Example 5 referring to fig. 2, a method for controlling moisture prevention for medical sterilization, which uses a pulse type vacuum sterilizer to sterilize Chinese medicinal powder, and uses 160 ℃ compressed air to preheat the Chinese medicinal powder before using saturated steam for sterilization. The pressure of the compressed air was 700Kpa.

The method comprises the following specific steps:

(1) Preheating: vacuumizing the sterilizing chamber to-80 KPa, inputting hot compressed air at 140 ℃ into the sterilizing chamber, raising the pressure to 265KPa, and keeping for 10 minutes; the method is circulated for 20 times, the 20 th sterilization chamber is vacuumized to-80 KPa, and compressed air with 140 ℃ heat is input into the sterilization chamber again, the pressure is raised to 265KPa, and the sterilization chamber is kept for 10 minutes; the temperature in the sterilized powder is up to 45 ℃;

(2) And (3) sterilization: vacuumizing the sterilizing chamber again to below-90 KPa for 40 min, and reducing water content of the medicinal powder; hot compressed air is again input into the sterilizing chamber, the pressure is increased to 265KPa, and the sterilizing chamber is kept for 10 minutes; the method is circulated for 20 times, the 20 th sterilization chamber is vacuumized to-80 KPa, and compressed air with 140 ℃ heat is input into the sterilization chamber again, the pressure is raised to 265KPa, and the sterilization chamber is kept for 10 minutes; the temperature in the sterilized powder reaches 100 ℃, the temperature is kept for 15 minutes, the internal chamber is exhausted to the door opening pressure, and the sterilization is finished.

Example 6, see FIG. 3, a method of controlling moisture protection for medical sterilization, wherein a pulse vacuum sterilizer is used to sterilize the powder, and compressed air at 110deg.C is used to preheat the powder before saturated steam sterilization. The pressure of the compressed air was 400Kpa.

The method comprises the following specific steps:

(1) Preheating: vacuumizing the sterilizing chamber to-60 KPa, inputting 110 ℃ hot compressed air into the sterilizing chamber, raising the pressure to 100KPa, and keeping for 2 minutes; the method is circulated for 10 times, the 10 th sterilization chamber is vacuumized to-60 KPa, compressed air with 110 ℃ is again input into the sterilization chamber, the pressure is raised to 100KPa, and the sterilization chamber is kept for 2 minutes; the temperature in the sterilized traditional Chinese medicine powder reaches 40 ℃;

(2) And (3) sterilization: vacuumizing the sterilizing chamber again to below-90 KPa for 40 min, and reducing water content of the medicinal powder; inputting hot compressed air into the sterilizing chamber again, increasing the pressure to 100KPa, keeping for 2 minutes, circulating for 10 times, vacuumizing the 10 th sterilizing chamber to-60 KPa, inputting 110 ℃ hot compressed air into the sterilizing chamber again, increasing the pressure to 100KPa, and keeping for 2 minutes; the temperature in the sterilized powder is up to 70 ℃; vacuumizing the sterilizing chamber to-80 KPa again, and inputting saturated steam into the sterilizing chamber to raise the temperature of the material to 105 ℃ which is the set temperature for sterilization; sterilizing at constant temperature for 15 minutes; exhausting the steam from the sterilizing chamber to 20KPa; vacuumizing the sterilizing chamber for 5 minutes to dry the sterilized matters; sterile air is returned to the sterilization chamber; and (5) finishing sterilization.

Example 7, see fig. 3, a method of controlling moisture protection for medical sterilization, wherein a pulse vacuum sterilizer is used to sterilize the powder, and compressed air at 160 ℃ is used to preheat the powder before saturated steam sterilization. The pressure of the compressed air was 700Kpa.

The method comprises the following specific steps:

(1) Preheating: vacuumizing the sterilizing chamber to-90 KPa, inputting 160 ℃ hot compressed air into the sterilizing chamber, raising the pressure to 300KPa, and keeping for 10 minutes; the method is circulated for 20 times, the 10 th sterilization chamber is vacuumized to-90 KPa, and compressed air with 160 ℃ heat is input into the sterilization chamber again, the pressure is raised to 300KPa, and the sterilization chamber is kept for 10 minutes; the temperature in the sterilized traditional Chinese medicine powder reaches 50 ℃;

(2) And (3) sterilization: vacuumizing the sterilizing chamber again to below-90 KPa for 60 minutes, and reducing the water content of the medicinal powder; the hot compressed air is input into the sterilizing chamber again, the pressure is increased to 300KPa, the sterilizing chamber is kept for 10 minutes, the circulating is carried out for 20 times, the sterilizing chamber is vacuumized for the 20 th time to-90 KPa, the hot compressed air at 160 ℃ is input into the sterilizing chamber again, the pressure is increased to 300KPa, and the sterilizing chamber is kept for 10 minutes; the temperature in the sterilized powder reaches 100 ℃; vacuumizing the sterilizing chamber to-95 KPa again, and inputting saturated steam into the sterilizing chamber to raise the temperature of the material to 121 ℃ which is the set temperature for sterilization; sterilizing at constant temperature for 30 minutes; exhausting the steam from the sterilizing chamber to 20KPa; vacuumizing the sterilizing chamber for 8 minutes to dry the sterilized matters; sterile air is returned to the sterilization chamber; and (5) finishing sterilization.

Example 8, refer to fig. 3, a method of controlling moisture protection for medical sterilization, which uses a pulse vacuum sterilizer to sterilize the Chinese medicinal powder, and uses 140 ℃ compressed air to preheat the medical instrument package or the Chinese medicinal powder before using saturated steam for sterilization. The pressure of the compressed air was 500Kpa.

The method comprises the following specific steps:

(1) Preheating: vacuumizing the sterilizing chamber to-80 KPa, inputting hot compressed air at 140 ℃ into the sterilizing chamber, raising the pressure to 265KPa, and keeping for 1-10 minutes; the method is circulated for 15 times, the 15 th sterilization chamber is vacuumized to-80 KPa, and compressed air with 140 ℃ heat is input into the sterilization chamber again, the pressure is raised to 265KPa, and the sterilization chamber is kept for 5 minutes; the temperature in the sterilized powder is up to 45 ℃;

(2) And (3) sterilization: vacuumizing the sterilizing chamber again to below-90 KPa for 40 min, and reducing water content of the medicinal powder; hot compressed air is again input into the sterilizing chamber, the pressure is increased to 265KPa, and the sterilizing chamber is kept for 5 minutes; the method is circulated for 15 times, the 5 th sterilization chamber is vacuumized to-80 KPa, and compressed air with 140 ℃ heat is input into the sterilization chamber again, the pressure is raised to 265KPa, and the sterilization chamber is kept for 5 minutes; the temperature in the sterilized powder reaches 80 ℃; vacuumizing the sterilizing chamber to-90 KPa again, and inputting saturated steam into the sterilizing chamber to raise the temperature of the material to the sterilizing set temperature of 121 ℃; sterilizing at constant temperature for 20 minutes; exhausting the steam from the sterilizing chamber to 20KPa; vacuumizing the sterilizing chamber for 6 minutes to dry the sterilized matters; sterile air is returned to the sterilization chamber; and (5) finishing sterilization.

Claims (10)

1. A medical sterilization moisture-proof control method is characterized in that: the method adopts a pulse type vacuum sterilizer to sterilize the medical instrument bag wrapped by the Chinese medicinal powder or the non-woven fabric, and adopts compressed air at 110-160 ℃ to preheat the medical instrument bag or the Chinese medicinal powder to be sterilized before using saturated steam for sterilization.

2. The method according to claim 1, wherein the compressed air has a pressure of 400Kpa to 700Kpa.

3. The medical sterilization moisture-proof control method according to claim 1 or 2, which is suitable for medical instrument package sterilization moisture-proof package control, and the preheating method is as follows: vacuumizing the sterilizing chamber to-60 KPa to-90 KPa, inputting compressed air at 110-160 ℃ into the sterilizing chamber, raising the pressure to 100 KPa-300 KPa, and keeping for 0-10 minutes; the method comprises the steps of circulating for N times, wherein N=1-5, vacuumizing an nth sterilizing chamber to-60 KPa to-90 KPa, inputting 110-160 ℃ compressed air into the sterilizing chamber again, increasing the pressure to 100 KPa-300 KPa, and keeping for 0-10 minutes; the temperature in the sterilized instrument bag reaches 55-80 ℃.

4. The medical sterilization moisture-proof control method according to claim 1 or 2, characterized in that: the method is suitable for controlling the sterilization moisture-proof bag of the medical instrument bag, and comprises the following specific steps:

preheating: vacuumizing the sterilizing chamber to-60 KPa to-90 KPa, inputting compressed air at 110-160 ℃ into the sterilizing chamber, raising the pressure to 100 KPa-300 KPa, and keeping for 0-10 minutes; the method is circulated for N times, wherein N=1 to 5, the nth sterilizing chamber is vacuumized to-60 KPa to-90 KPa, compressed air with the temperature of 110 to 160 ℃ is input into the sterilizing chamber again, the pressure is increased to 100KPa to 300KPa, and the sterilizing chamber is kept for 0 to 10 minutes; the temperature in the sterilized instrument package reaches 55-80 ℃;

and (3) sterilization: after preheating, vacuumizing the sterilizing chamber to-80 KPa to-95 KPa, and inputting saturated steam into the sterilizing chamber to raise the pressure to-60 KPa to 0KPa; vacuumizing the sterilizing chamber again to-80 KPa to-95 KPa, and then inputting saturated steam into the sterilizing chamber to raise the pressure to-60 KPa to 0KPa; vacuumizing the sterilizing chamber again to-80 KPa to-95 KPa, and inputting saturated steam into the sterilizing chamber to raise the pressure to 50KPa to 120KPa; the pressure of the exhaust steam of the sterilizing chamber is reduced to 10 KPa-40 KPa; again, the saturated steam pressure is input into the sterilizing chamber and is increased to 206KPa; sterilizing at constant temperature for 6-8 min;

and (3) drying: exhausting the steam from the sterilizing chamber to 20KPa; vacuumizing for 5-8 minutes to dry the sterilized material; sterile air is returned to the sterilization chamber; the sterilization cycle is ended.

5. The method for controlling moisture resistance for sterilization of medicines according to claim 4, comprising the steps of:

(1) Preheating: vacuumizing the sterilizing chamber to-80 KPa, inputting hot compressed air at 140 ℃ into the sterilizing chamber, raising the pressure to 265KPa, and keeping for 0-10 minutes; the method comprises the steps of circulating for N times, wherein N=1-5, vacuumizing an nth sterilizing chamber to-80 KPa, inputting compressed air at 140 ℃ into the sterilizing chamber again, raising the pressure to 265KPa, and keeping for 1-10 minutes; the temperature in the sterilized instrument package reaches 70 ℃;

(2) And (3) sterilization: after preheating, vacuumizing the sterilizing chamber to-90 KPa, and inputting saturated steam into the sterilizing chamber to raise the pressure to-47 KPa; vacuumizing the sterilizing chamber again to-90 KPa, and then inputting saturated steam into the sterilizing chamber to rise to-30 KPa; vacuumizing the sterilizing chamber again to-90 KPa, and inputting saturated steam into the sterilizing chamber to raise the pressure to 70KPa; the exhaust pressure of the sterilizing chamber is reduced to 20KPa; again, the saturated steam pressure is input into the sterilizing chamber and is increased to 206KPa; sterilizing at constant temperature for 6-8 min;

(3) And (3) drying: exhausting the steam from the sterilizing chamber to 20KPa; vacuumizing the sterilizing chamber for 5-8 minutes to dry the sterilized matters; sterile air is returned to the sterilization chamber; and (5) finishing sterilization.

6. The medical sterilization moisture-proof control method according to claim 1 or 2, which is suitable for sterilization moisture-proof control of traditional Chinese medicine powder, and the preheating method is as follows: vacuumizing the sterilizing chamber to-60 KPa to-90 KPa, inputting 110-160 ℃ hot compressed air into the sterilizing chamber, raising the pressure to 100 KPa-300 KPa, and keeping for 0-10 minutes; the method comprises the steps of circulating for N times, wherein N=1-20, vacuumizing an nth sterilizing chamber to-60 KPa to-90 KPa, inputting 110-160 ℃ hot compressed air into the sterilizing chamber again, increasing the pressure to 100KPa to 300KPa, and keeping the pressure for 0-10 minutes; the temperature in the sterilized medicine powder reaches 40-50 ℃.

7. The medical sterilization moisture-proof control method according to claim 6, which is suitable for sterilization moisture-proof control of traditional Chinese medicine powder, and comprises the following specific steps:

(1) Preheating: vacuumizing the sterilizing chamber to-60 KPa to-90 KPa, inputting 110-160 ℃ hot compressed air into the sterilizing chamber, raising the pressure to 100 KPa-300 KPa, and keeping for 0-10 minutes; the method comprises the steps of circulating N times, namely, N=1 to 20, vacuumizing an nth sterilizing chamber to-60 KPa to-90 KPa, inputting 110 to 160 ℃ hot compressed air into the sterilizing chamber again, increasing the pressure to 100KPa to 300KPa, and keeping the pressure for 0 to 10 minutes; the temperature in the sterilized powder reaches 40-50 ℃;

(2) And (3) sterilization: vacuumizing the sterilizing chamber again to below-90 KPa for 40-60 min, and reducing the water content of the medicinal powder; inputting hot compressed air into the sterilizing chamber again, and raising the pressure to 100 KPa-300 KPa, and keeping for 0-10 minutes; the method comprises the steps of circulating for N times, wherein N=1-20, vacuumizing an nth sterilizing chamber to-60 KPa to-90 KPa, inputting 110-160 ℃ hot compressed air into the sterilizing chamber again, increasing the pressure to 100 KPa-300 KPa, and keeping for 0-10 minutes; the temperature in the sterilized powder reaches 100-110 ℃, the temperature is kept for 10-30 minutes, the internal chamber is exhausted to the door opening pressure, and the sterilization is finished.

8. The medical sterilization moisture-proof control method according to claim 7, characterized by comprising the specific steps of:

(1) Preheating: vacuumizing the sterilizing chamber to-80 KPa, inputting hot compressed air at 140 ℃ into the sterilizing chamber, raising the pressure to 265KPa, and keeping for 1-10 minutes; the method comprises the steps of circulating for N times, wherein N=1-20, vacuumizing an nth sterilizing chamber to-80 KPa, inputting hot compressed air at 140 ℃ into the sterilizing chamber again, raising the pressure to 265KPa, and keeping for 1-10 minutes; the temperature in the sterilized powder is up to 45 ℃;

(2) And (3) sterilization: vacuumizing the sterilizing chamber again to below-90 KPa for 40 min, and reducing water content of the medicinal powder; inputting hot compressed air into the sterilizing chamber again, and raising the pressure to 265KPa, and keeping for 1-10 minutes; the method comprises the steps of circulating for N times, wherein N=1-20, vacuumizing an nth sterilizing chamber to-80 KPa, inputting hot compressed air at 140 ℃ into the sterilizing chamber again, raising the pressure to 265KPa, and keeping for 1-10 minutes; the temperature in the sterilized powder reaches 100 ℃, the temperature is kept for 15 minutes, the internal chamber is exhausted to the door opening pressure, and the sterilization is finished.

9. The medical sterilization moisture-proof control method according to claim 6, which is suitable for sterilization moisture-proof control of traditional Chinese medicine powder, and comprises the following specific steps:

(1) Preheating: vacuumizing the sterilizing chamber to-60 KPa to-90 KPa, inputting 110-160 ℃ hot compressed air into the sterilizing chamber, raising the pressure to 100 KPa-300 KPa, and keeping for 0-10 minutes; the method comprises the steps of circulating N times, namely, N=1 to 20, vacuumizing an nth sterilizing chamber to-60 KPa to-90 KPa, inputting 110 to 160 ℃ hot compressed air into the sterilizing chamber again, increasing the pressure to 100KPa to 300KPa, and keeping the pressure for 0 to 10 minutes; the temperature in the sterilized traditional Chinese medicine powder reaches 40-50 ℃;

(2) And (3) sterilization: vacuumizing the sterilizing chamber again to below-90 KPa for 40-60 min, and reducing the water content of the medicinal powder; inputting hot compressed air into the sterilizing chamber again, increasing the pressure to 100 KPa-300 KPa, keeping for 0-10 minutes, circulating for N times, wherein N=1-20, vacuumizing the sterilizing chamber for the nth time to-60 KPa to-90 KPa, inputting hot compressed air at 110-160 ℃ into the sterilizing chamber again, increasing the pressure to 100 KPa-300 KPa, and keeping for 0-10 minutes; the temperature in the sterilized powder reaches 70-100 ℃; vacuumizing the sterilizing chamber again to-80 KPa to-95 KPa, and inputting saturated steam into the sterilizing chamber to raise the temperature of the material to 105-121 ℃ which is the set temperature for sterilization; sterilizing for 15-30 minutes at constant temperature; exhausting the steam from the sterilizing chamber to 20KPa; vacuumizing the sterilizing chamber for 5-8 minutes to dry the sterilized matters; sterile air is returned to the sterilization chamber; and (5) finishing sterilization.

10. The medical sterilization moisture-proof control method according to claim 9, characterized by comprising the specific steps of:

(1) Preheating: vacuumizing the sterilizing chamber to-80 KPa, inputting hot compressed air at 140 ℃ into the sterilizing chamber, raising the pressure to 265KPa, and keeping for 1-10 minutes; the method comprises the steps of circulating for N times, wherein N=1-20, vacuumizing an nth sterilizing chamber to-80 KPa, inputting hot compressed air at 140 ℃ into the sterilizing chamber again, raising the pressure to 265KPa, and keeping for 1-10 minutes; the temperature in the sterilized powder is up to 45 ℃;

(2) And (3) sterilization: vacuumizing the sterilizing chamber again to below-90 KPa for 40 min, and reducing water content of the medicinal powder; inputting hot compressed air into the sterilizing chamber again, and raising the pressure to 265KPa, and keeping for 1-10 minutes; the method comprises the steps of circulating for N times, wherein N=1-20, vacuumizing an nth sterilizing chamber to-80 KPa, inputting hot compressed air at 140 ℃ into the sterilizing chamber again, raising the pressure to 265KPa, and keeping for 1-10 minutes; the temperature in the sterilized powder reaches 80 ℃; vacuumizing the sterilizing chamber to-90 KPa again, and inputting saturated steam into the sterilizing chamber to raise the temperature of the material to 105-121 ℃ which is the set temperature for sterilization; sterilizing for 15-30 minutes at constant temperature; exhausting the steam from the sterilizing chamber to 20KPa; vacuumizing the sterilizing chamber for 5-8 minutes to dry the sterilized matters; sterile air is returned to the sterilization chamber; and (5) finishing sterilization.