CN106620752A - Sterilizing method for low temperature steam sterilized traditional Chinese medicine - Google Patents
Sterilizing method for low temperature steam sterilized traditional Chinese medicine Download PDFInfo
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- CN106620752A CN106620752A CN201710005970.4A CN201710005970A CN106620752A CN 106620752 A CN106620752 A CN 106620752A CN 201710005970 A CN201710005970 A CN 201710005970A CN 106620752 A CN106620752 A CN 106620752A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
- A61L2/0023—Heat
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/26—Accessories or devices or components used for biocidal treatment
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/10—Apparatus features
- A61L2202/12—Apparatus for isolating biocidal substances from the environment
- A61L2202/121—Sealings, e.g. doors, covers, valves, sluices
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/20—Targets to be treated
- A61L2202/21—Pharmaceuticals, e.g. medicaments, artificial body parts
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- Apparatus For Disinfection Or Sterilisation (AREA)
Abstract
The invention provides a sterilizing method for low temperature steam sterilized traditional Chinese medicine, and relates to the technical field of traditional Chinese medicine sterilizing methods. The sterilizing method comprises the following steps: placing traditional Chinese medicine into a sterilizing room; vacuuming the sterilizing room; introducing high-temperature and high-pressure steam into the sterilizing room; when the pressure in the sterilizing room reaches a sterilizing pressure, preheating for stabilizing; continually introducing high-temperature and high-pressure steam, so that the temperature in the sterilizing room rises to a sterilizing temperature; starting sterilization; entering a drying process after finishing the sterilization; drying and standing for 24 hours to wait for the growth of spores; sterilizing once again; repeating the waiting and sterilizing processes after finishing the sterilization; finishing the sterilization. The sterilizing method is convenient to run, energy consumption is lowered greatly, and the original efficacy, characteristic and uniformity of the traditional Chinese medicine are kept; meanwhile, a plurality of bacteria such as molds and escherichia coli in traditional Chinese medicinal powder are killed fully, and a large amount of energy and material resource cost is saved; the sterilizing method is a novel and environment-friendly sterilizing method being worthy of wide popularization.
Description
Technical field
The present invention relates to Chinese medicine sterilizing methods technical field, and in particular to a kind of sterilizing side of Low Temperature Steam sterilizing Chinese medicine
Method.
Background technology
The new edition that state food pharmaceuticals administration general bureau promulgates《GMP》To Chinese medicine and its system
The disinfecting action of agent has done detailed regulation,《Chinese Pharmacopoeia》Also the limit test of microbe of Chinese medicine and its preparation is proposed sternly
The requirement of lattice, disinfecting action as the key operating units for affecting Chinese medicine and its quality of the pharmaceutical preparations, will directly affect drug safety,
Effective and steady quality.At present the sterilizing present situation of Chinese medicine is unsterilised or using high temperature and high pressure steam sterilizing, is not done at sterilizing
Chinese medicine is directly cleaned post-drying by the Chinese medicine of reason, into crusher in crushing, is filtered, and traditional Chinese medicine powder is formed, by the traditional Chinese medicine powder carried disease germs
Directly packaging is sold, though the efficiency of original Chinese medicine can be kept, proterties, because containing miscellaneous bacteria (such as mould, Escherichia coli)
Easily produce and go mouldy, regrowth other bacteriums cause pathogen of the medicine with harmfulness, cause medicine to contain different bacterial classifications
And make efficiency play different effect, it is impossible to reach the proterties homogeneity of medicine；High temperature and high pressure steam sterilizing is high using high temperature
Pressure steam is sterilized to Chinese medicine, is dried, and aseptic traditional Chinese medicine powder is sold in aseptic area through packaging, during the method can keep original
The proterties homogeneity of medicinal powder, but medicinal powder can be gelatinized through high-temperature process containing sugar moieties, and other parts are likely to because HTHP steams
There is series of chemical in vapour process, cause the actual content of sterilizing traditional Chinese medicine powder, composition to have very big change, it is impossible to protect
Hold original Chinese Herbs.
The content of the invention
(1) technical problem for solving
For the deficiencies in the prior art, a kind of method of Chinese medicine the invention provides low temperature and low pressure steam sterilizes so that in
While medicine keeps original efficiency, homogeneity, the various bacteria in Chinese medicine is thoroughly killed, save mass energy, goods and materials cost.
(2) technical scheme
To realize object above, the present invention is achieved by the following technical programs：
A kind of sterilizing methods of Low Temperature Steam sterilizing Chinese medicine, step is as follows：
(1) sterilizing installation Qianmen is opened, the pallet that will be equipped with Chinese medicine puts into vehicle of sterilization, and vehicle of sterilization propulsion sterilizing chamber closes
Sterilizing installation Qianmen；
(2) sterilizing parameter is set；
(3) vacuum system and chuck and moistureproof tubulation vacuum valve are opened, when vacuum buffer pressure inside the tank reaches setting value
When, to open and enter high temperature and high pressure steam into steam valve to chuck and moistureproof tubulation and open chuck and moistureproof tubulation steam discharge is hydrophobic
Valve, makes chuck and moistureproof row overpressure stable in setting value, pre- thermally-stabilised；
(4) constantly high temperature and high pressure steam is entered to sterilizing chamber, steam quickly becomes low temperature and low pressure steam into after vacuum environment,
Simultaneously sterilizing chamber is constantly hydrophobic in vacuum buffer tank, the pressure stability of vacuum buffer tank setting higher limit and lower limit it
Between, when the room temperature that sterilizes reaches setting value, it is automatically brought to sterilizing stroke；
(5) after entering sterilizing stroke, continue to enter high temperature and high pressure steam to sterilizing chamber, while sterilizing chamber is constantly hydrophobic to vacuum
Surge tank, keeps the vapo(u)rous degree of sterilizing chamber, it is ensured that the temperature stabilization of Chinese medicine is sterilized in setting value；
(6) after sterilizing terminates, close into steam valve, vacuum system continues to vacuumize, and is vacuum dried；
(7) vacuum, steam discharge hydrophobic valve are closed, opens the air valve that makes the return trip empty, after time air time is arrived, close the air valve that makes the return trip empty
Door, opens vacuum, steam discharge hydrophobic valve, continues to vacuumize, and is vacuum dried；
(8) after drying terminates, power supply is not closed, after standing 24h, repeat step (2)-(6)；
(9) after step (7) terminates, power supply is not still closed, after standing 24h, repeatedly repeat step (2)-(6) again；
(10) sterilizing terminates, and opens back door and takes out Chinese medicine, into next process.
Preferably, step (2) sterilizing parameter is：Chuck and moistureproof row overpressure (- 0.025)-(- 0.035)
Mpa, 80 DEG C of sterilising temp, sterilization time 60min, pre- heat-stable time 20min, vacuum buffer pressure tank (- 0.07)-(-
0.09) Mpa, vacuum drying time 20min returns air time 10min.
Preferably, the Chinese medicine is traditional Chinese medicine powder or Chinese medicine.
(3) beneficial effect
A kind of sterilizing methods of Chinese medicine the invention provides Low Temperature Steam sterilizes, are positioned at going out for traditional Chinese medicine powder or Chinese medicine
Bacterium, isolation of the sterilizing installation comprising front/rear door is arranged, and can effectively ensure that being effectively isolated for clear area and aseptic area；Vacuum system sets
To negative pressure, vacuum sterilization is realized；Vacuum buffer tank can reduce equipment noise, while pressure when ensureing that equipment steam discharge is hydrophobic is steady
It is fixed；Chuck and moistureproof tubulation can play a part of heating and thermal insulation；The preheating stabilization sub stage causes sterilizing chamber to go out reaching before sterilizing
First sterilization pressure stablized between bacterium temperature, is gradually heated up on the basis of pressure stability, whole process is incremental, is conducive to
The control of sterilising conditions；Into high temperature and high pressure steam quickly become low temperature and low pressure steam into after vacuum environment, while steam discharge
Hydrophobic valve is constantly hydrophobic to vacuum buffer tank, it is ensured that the vapo(u)rous degree of sterilizing chamber so that whole sterilization process temperature with
Pressure is maintained constant；24h sterilizings are waited repeatedly, to be waited and can further kill newly-generated thin of gemma after gemma growth
Bacterium, reaches more preferable sterilization effect；Avoid causing to be modified to environment, to Chinese medicine using bactericidal agent；The sterilizing methods
Operation is convenient, considerably reduces energy resource consumption, maintains original Chinese medicine efficiency, characteristic, homogeneity, while and guarantee Chinese medicine
The thorough killing of the majority bacterial species such as mould (60 DEG C of heatproof), Escherichia coli (80 DEG C of heatproof) in powder, saves a large amount of energy
Source, goods and materials cost, are a novel green sterilizing methods that should be widely promoted.
Description of the drawings
Fig. 1 is sterilizing installation general assembly drawing, and each mark is as follows in figure：
1st, Qianmen, 2, sterilizing chamber, 3, chuck, 4, moistureproof tubulation, 5, back door, 6, vacuum buffer tank, 7, vacuum system, 8, enter
Steam valve, 9, make the return trip empty air valve, 10, vacuum valve, 11, steam discharge hydrophobic valve.
Specific embodiment
To make purpose, technical scheme and the advantage of the embodiment of the present invention clearer, below in conjunction with the embodiment of the present invention,
Technical scheme in the embodiment of the present invention is clearly and completely described, it is clear that described embodiment is the present invention one
Divide embodiment, rather than the embodiment of whole.Based on the embodiment in the present invention, those of ordinary skill in the art are not making
The every other embodiment obtained under the premise of creative work, belongs to the scope of protection of the invention.
Embodiment 1：
A kind of sterilizing methods of Low Temperature Steam sterilizing traditional Chinese medicine powder, step is as follows：
(1) sterilizing installation Qianmen is opened, traditional Chinese medicine powder is put into pallet, pallet is put into vehicle of sterilization, and vehicle of sterilization is advanced
Sterilizing chamber, closes sterilizing installation Qianmen；
(2) setting sterilizing parameters：Sterilization pressure -0.030Mpa, 80 DEG C of sterilising temp, sterilization time 60min, preheating
Stabilization time 20min, vacuum buffer tank pressure upper limit -0.07Mpa, threshold pression -0.09Mpa, vacuum drying time 20min,
Return air time 10min；
(3) open vacuum system to vacuumize, while opening chuck and moistureproof tubulation vacuum valve, vacuum buffer pressure inside the tank
Begin to decline, when -0.09Mpa is dropped to, open into steam valve and enter high temperature and high pressure steam to chuck and moistureproof tubulation, while
Chuck and moistureproof tubulation steam discharge hydrophobic valve are opened, when chuck and moistureproof row overpressure are stablized in -0.030Mpa, enters pre-
Thermally-stabilised stage, stable 20min；
(4) constantly to sterilizing chamber high temperature and high pressure steam is entered, the sterilizing chamber that high temperature and high pressure steam is entered under vacuum state, rapidly
Diverging heat, becomes low temperature and low pressure steam, while sterilizing chamber is constantly hydrophobic to vacuum buffer tank, the pressure stability of vacuum buffer tank
Between the Mpa of (- 0.07)-(- 0.09), be further ensured that the saturation degree of indoor low temperature low-pressure steam, with constantly enter steam,
Hydrophobic, the low temperature and low pressure steam saturation degree of sterilizing chamber is improved constantly, and the indoor traditional Chinese medicine powder temperature that sterilizes constantly is increased to 80 DEG C, this
When be automatically brought to sterilizing stroke；
(5) after entering sterilizing stroke, continue to enter high temperature and high pressure steam to sterilizing chamber, while sterilizing chamber is constantly hydrophobic to vacuum
Surge tank, keeps the vapo(u)rous degree of sterilizing chamber, it is ensured that at 80 DEG C, sterilize the temperature stabilization of traditional Chinese medicine powder 60min；
(6) after sterilizing terminates, dry trip is automatically brought to, closes into steam valve and stop entering HTHP steaming to sterilizing chamber
Vapour, vacuum system continues to vacuumize sterilizing chamber, is vacuum dried 20min；
(7) vacuum, steam discharge hydrophobic valve are closed, opens the air valve 10min that makes the return trip empty, close the air valve that makes the return trip empty, be again turned on
Vacuum, steam discharge hydrophobic valve, vacuumize to sterilizing chamber, are dried 20min；
(8) after drying terminates, power supply is not closed, stands 24h, wait the gemma growth of the bacterium that sterilized, after 24h, repeated
Step (2)-(7), the killing bacteria that gemma has just been grown out；
(9) after step (8) terminates, power supply is not still closed, stands 24h, wait the gemma growth of residual bacterial, after 24h,
Repeat step (2)-(7), last remaining bacterium is thoroughly killed.
(10) after step (9) terminates, whole sterilization process terminates, and opens back door and takes out traditional Chinese medicine powder, into next process.
Embodiment 2：
A kind of sterilizing methods of Low Temperature Steam sterilizing Chinese medicine, step is as follows：
(1) sterilizing installation Qianmen is opened, Chinese medicine is put into pallet, pallet is put into vehicle of sterilization, and vehicle of sterilization is advanced
Sterilizing chamber, closes sterilizing installation Qianmen；
(2) setting sterilizing parameters：Sterilization pressure -0.035Mpa, 80 DEG C of sterilising temp, sterilization time 60min, preheating
Stabilization time 20min, vacuum buffer tank pressure upper limit -0.07Mpa, threshold pression -0.09Mpa, vacuum drying time 25min,
Return air time 10min；
(3) open vacuum system to vacuumize, while opening chuck and moistureproof tubulation vacuum valve, vacuum buffer pressure inside the tank
Begin to decline, when -0.09Mpa is dropped to, open into steam valve and enter high temperature and high pressure steam to chuck and moistureproof tubulation, while
Chuck and moistureproof tubulation steam discharge hydrophobic valve are opened, when chuck and moistureproof row overpressure are stablized in -0.035Mpa, enters pre-
Thermally-stabilised stage, stable 20min；
(4) constantly to sterilizing chamber high temperature and high pressure steam is entered, the sterilizing chamber that high temperature and high pressure steam is entered under vacuum state, rapidly
Diverging heat, becomes low temperature and low pressure steam, while sterilizing chamber is constantly hydrophobic to vacuum buffer tank, the pressure stability of vacuum buffer tank
Between the Mpa of (- 0.07)-(- 0.09), be further ensured that the saturation degree of indoor low temperature low-pressure steam, with constantly enter steam,
Hydrophobic, the low temperature and low pressure steam saturation degree of sterilizing chamber is improved constantly, and the indoor Chinese medicine temperature that sterilizes constantly is increased to 80 DEG C, this
When be automatically brought to sterilizing stroke；
(5) after entering sterilizing stroke, continue to enter high temperature and high pressure steam to sterilizing chamber, while sterilizing chamber is constantly hydrophobic to vacuum
Surge tank, keeps the vapo(u)rous degree of sterilizing chamber, it is ensured that at 80 DEG C, sterilize the temperature stabilization of Chinese medicine 60min；
(6) after sterilizing terminates, dry trip is automatically brought to, closes into steam valve and stop entering HTHP steaming to sterilizing chamber
Vapour, vacuum system continues to vacuumize sterilizing chamber, is vacuum dried 25min；
(7) vacuum, steam discharge hydrophobic valve are closed, opens the air valve 10min that makes the return trip empty, close the air valve that makes the return trip empty, be again turned on
Vacuum, steam discharge hydrophobic valve, vacuumize to sterilizing chamber, are dried 25min；
(8) after drying terminates, power supply is not closed, stands 24h, wait the gemma growth of the bacterium that sterilized, after 24h, repeated
Step (2)-(7), the killing bacteria that gemma has just been grown out；
(9) after step (8) terminates, power supply is not still closed, stands 24h, wait the gemma growth of residual bacterial, after 24h,
Repeat step (2)-(7), last remaining bacterium is thoroughly killed.
(10) after step (9) terminates, whole sterilization process terminates, and opens back door and takes out Chinese medicine, into next process.
Embodiment 3：
A kind of sterilizing methods of Low Temperature Steam sterilizing traditional Chinese medicine powder, step is as follows：
(1) sterilizing installation Qianmen is opened, traditional Chinese medicine powder is put into pallet, pallet is put into vehicle of sterilization, and vehicle of sterilization is advanced
Sterilizing chamber, closes sterilizing installation Qianmen；
(2) setting sterilizing parameters：Sterilization pressure -0.035Mpa, 85 DEG C of sterilising temp, sterilization time 90min, preheating
Stabilization time 30min, vacuum buffer tank pressure upper limit -0.06Mpa, threshold pression -0.08Mpa, vacuum drying time 20min,
Return air time 10min；
(3) open vacuum system to vacuumize, while opening chuck and moistureproof tubulation vacuum valve, vacuum buffer pressure inside the tank
Begin to decline, when -0.08Mpa is dropped to, open into steam valve and enter high temperature and high pressure steam to chuck and moistureproof tubulation, while
Chuck and moistureproof tubulation steam discharge hydrophobic valve are opened, when chuck and moistureproof row overpressure are stablized in -0.035Mpa, enters pre-
Thermally-stabilised stage, stable 30min；
(4) constantly to sterilizing chamber high temperature and high pressure steam is entered, the sterilizing chamber that high temperature and high pressure steam is entered under vacuum state, rapidly
Diverging heat, becomes low temperature and low pressure steam, while sterilizing chamber is constantly hydrophobic to vacuum buffer tank, the pressure stability of vacuum buffer tank
Between the Mpa of (- 0.06)-(- 0.08), be further ensured that the saturation degree of indoor low temperature low-pressure steam, with constantly enter steam,
Hydrophobic, the low temperature and low pressure steam saturation degree of sterilizing chamber is improved constantly, and the indoor traditional Chinese medicine powder temperature that sterilizes constantly is increased to 85 DEG C, this
When be automatically brought to sterilizing stroke；
(5) after entering sterilizing stroke, continue to enter high temperature and high pressure steam to sterilizing chamber, while sterilizing chamber is constantly hydrophobic to vacuum
Surge tank, keeps the vapo(u)rous degree of sterilizing chamber, it is ensured that at 85 DEG C, sterilize the temperature stabilization of traditional Chinese medicine powder 90min；
(6) after sterilizing terminates, dry trip is automatically brought to, closes into steam valve and stop entering HTHP steaming to sterilizing chamber
Vapour, vacuum system continues to vacuumize sterilizing chamber, is vacuum dried 20min；
(7) vacuum, steam discharge hydrophobic valve are closed, opens the air valve 10min that makes the return trip empty, close the air valve that makes the return trip empty, be again turned on
Vacuum, steam discharge hydrophobic valve, vacuumize to sterilizing chamber, are dried 20min；
(8) after drying terminates, power supply is not closed, stands 24h, wait the gemma growth of the bacterium that sterilized, after 24h, repeated
Step (2)-(7), the killing bacteria that gemma has just been grown out；
(9) after step (8) terminates, power supply is not still closed, stands 24h, wait the gemma growth of residual bacterial, after 24h,
Repeat step (2)-(7), last remaining bacterium is thoroughly killed.
(10) after step (9) terminates, whole sterilization process terminates, and opens back door and takes out traditional Chinese medicine powder, into next process.
To sum up, the embodiment of the present invention has the advantages that：
A kind of sterilizing methods of Chinese medicine the invention provides Low Temperature Steam sterilizes, are to go up all not had both at home and abroad at present
The method for planting Low Temperature Steam sterilizing Chinese medicine, can thoroughly solve the present situation that Chinese medicine can not sterilize or high-temperature sterilization is modified, be a kind of
Unique novel low temperature sterilization method, is sterilized using Low Temperature Steam, and sterilising temp is low, reduces equipment plus thermal energy consumption, saves
Equipment operation cost and substantial amounts of manpower and materials, also save working link in the middle of a lot.
It should be noted that herein, such as first and second or the like relational terms are used merely to a reality
Body or operation make a distinction with another entity or operation, and not necessarily require or imply these entities or deposit between operating
In any this actual relation or order.And, term " including ", "comprising" or its any other variant are intended to
Nonexcludability is included, so that a series of process, method, article or equipment including key elements not only will including those
Element, but also including other key elements being not expressly set out, or also include for this process, method, article or equipment
Intrinsic key element.In the absence of more restrictions, the key element for being limited by sentence "including a ...", it is not excluded that
Also there is other identical element in process, method, article or equipment including the key element.
Above example only to illustrate technical scheme, rather than a limitation；Although with reference to the foregoing embodiments
The present invention has been described in detail, it will be understood by those within the art that：It still can be to aforementioned each enforcement
Technical scheme described in example is modified, or carries out equivalent to which part technical characteristic；And these modification or
Replace, do not make the spirit and scope of the essence disengaging various embodiments of the present invention technical scheme of appropriate technical solution.
Claims (3)
1. Low Temperature Steam sterilize Chinese medicine a kind of sterilizing methods, it is characterised in that step is as follows：
(1) sterilizing installation Qianmen is opened, the pallet that will be equipped with Chinese medicine puts into vehicle of sterilization, and vehicle of sterilization propulsion sterilizing chamber closes sterilizing
Equipment Qianmen；
(2) sterilizing parameter is set；
(3) vacuum system and chuck and moistureproof tubulation vacuum valve are opened, when vacuum buffer pressure inside the tank reaches setting value, is opened
Open and enter high temperature and high pressure steam into steam valve to chuck and moistureproof tubulation and open chuck and moistureproof tubulation steam discharge hydrophobic valve,
Make chuck and moistureproof row overpressure stable in setting value, it is pre- thermally-stabilised；
(4) constantly high temperature and high pressure steam is entered to sterilizing chamber, steam quickly becomes low temperature and low pressure steam into after vacuum environment, while
Sterilizing chamber is constantly hydrophobic in vacuum buffer tank, the pressure stability of vacuum buffer tank between the higher limit and lower limit of setting,
When the room temperature that sterilizes reaches setting value, sterilizing stroke is automatically brought to；
(5) after entering sterilizing stroke, continue to enter high temperature and high pressure steam to sterilizing chamber, while sterilizing chamber is constantly hydrophobic to vacuum buffer
Tank, keeps the vapo(u)rous degree of sterilizing chamber, it is ensured that the temperature stabilization of Chinese medicine is sterilized in setting value；
(6) after sterilizing terminates, close into steam valve, vacuum system continues to vacuumize, and is vacuum dried；
(7) vacuum, steam discharge hydrophobic valve are closed, opens the air valve that makes the return trip empty, after time air time is arrived, close the air valve that makes the return trip empty, beaten
Vacuum, steam discharge hydrophobic valve are opened, continues to vacuumize, be vacuum dried；
(8) after drying terminates, power supply is not closed, after standing 24h, repeat step (2)-(6)；
(9) after step (7) terminates, power supply is not still closed, after standing 24h, repeatedly repeat step (2)-(6) again；
(10) sterilizing terminates, and opens back door and takes out Chinese medicine, into next process.
2. low temperature and low pressure steam as claimed in claim 1 sterilizes the method for Chinese medicine, it is characterised in that step (2) sterilizing
Parameter is：Chuck and protection against the tide row overpressure (- 0.025)-(- 0.035) Mpa, 80 DEG C of sterilising temp, sterilization time 60min, in advance
Heat-stable time 20min, vacuum buffer pressure tank (- 0.07)-(- 0.09) Mpa, vacuum drying time 20min returns air time
10min。
3. low temperature and low pressure steam as claimed in claim 1 sterilizes the method for Chinese medicine, it is characterised in that the Chinese medicine is traditional Chinese medicine powder
Or Chinese medicine.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710005970.4A CN106620752A (en) | 2017-01-05 | 2017-01-05 | Sterilizing method for low temperature steam sterilized traditional Chinese medicine |
| PCT/CN2017/093269 WO2018126639A1 (en) | 2017-01-05 | 2017-07-18 | Sterilization method for low-temperature steam sterilization of chinese medicine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710005970.4A CN106620752A (en) | 2017-01-05 | 2017-01-05 | Sterilizing method for low temperature steam sterilized traditional Chinese medicine |
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| CN106620752A true CN106620752A (en) | 2017-05-10 |
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| CN201710005970.4A Pending CN106620752A (en) | 2017-01-05 | 2017-01-05 | Sterilizing method for low temperature steam sterilized traditional Chinese medicine |
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| WO (1) | WO2018126639A1 (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018126639A1 (en) * | 2017-01-05 | 2018-07-12 | 连云港佑源医药设备制造有限公司 | Sterilization method for low-temperature steam sterilization of chinese medicine |
| CN108653757A (en) * | 2018-05-29 | 2018-10-16 | 江西中医药大学 | A kind of horizontal low temperature sterilizing installation and low temperature sterilization method |
| CN109620987A (en) * | 2019-01-25 | 2019-04-16 | 华东理工大学 | A kind of Chinese medicine low temperature interval combination sterilization |
| CN110585454A (en) * | 2019-10-25 | 2019-12-20 | 安徽金寨乔康药业有限公司 | Ganoderma lucidum spore powder moist heat sterilization equipment |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109568629B (en) * | 2018-12-29 | 2024-02-27 | 深圳市怀德科技发展有限公司 | Intelligent dosing metering system and air disinfection device |
| CN111617269A (en) * | 2020-06-11 | 2020-09-04 | 连云港佑源医药设备制造有限公司 | Sterilizing and packaging treatment device for Chinese patent medicine pills |
| CN116350812A (en) * | 2023-03-30 | 2023-06-30 | 江苏中兴药业有限公司 | Sterilizing system and sterilizing method for pine cone powder |
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| CN103394106A (en) * | 2013-07-30 | 2013-11-20 | 山东新华医疗器械股份有限公司 | Steam sterilizer and sterilization process |
| CN204319330U (en) * | 2014-11-13 | 2015-05-13 | 天津市滨海新区博茂源生物科技有限公司 | A kind of edible fungi sterilization device |
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| CN106620752A (en) * | 2017-01-05 | 2017-05-10 | 连云港佑源医药设备制造有限公司 | Sterilizing method for low temperature steam sterilized traditional Chinese medicine |
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| CN103394106A (en) * | 2013-07-30 | 2013-11-20 | 山东新华医疗器械股份有限公司 | Steam sterilizer and sterilization process |
| CN204319330U (en) * | 2014-11-13 | 2015-05-13 | 天津市滨海新区博茂源生物科技有限公司 | A kind of edible fungi sterilization device |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018126639A1 (en) * | 2017-01-05 | 2018-07-12 | 连云港佑源医药设备制造有限公司 | Sterilization method for low-temperature steam sterilization of chinese medicine |
| CN108653757A (en) * | 2018-05-29 | 2018-10-16 | 江西中医药大学 | A kind of horizontal low temperature sterilizing installation and low temperature sterilization method |
| CN109620987A (en) * | 2019-01-25 | 2019-04-16 | 华东理工大学 | A kind of Chinese medicine low temperature interval combination sterilization |
| CN109620987B (en) * | 2019-01-25 | 2020-10-27 | 华东理工大学 | Low-temperature intermittent combined sterilization method for traditional Chinese medicine |
| CN110585454A (en) * | 2019-10-25 | 2019-12-20 | 安徽金寨乔康药业有限公司 | Ganoderma lucidum spore powder moist heat sterilization equipment |
| CN110585454B (en) * | 2019-10-25 | 2021-04-13 | 安徽金寨乔康药业有限公司 | Ganoderma lucidum spore powder moist heat sterilization equipment |
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| Publication number | Publication date |
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| WO2018126639A1 (en) | 2018-07-12 |
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