CN1166372C - Formula of medicine for treating myopia and preparation process thereof - Google Patents
Formula of medicine for treating myopia and preparation process thereof Download PDFInfo
- Publication number
- CN1166372C CN1166372C CNB991131835A CN99113183A CN1166372C CN 1166372 C CN1166372 C CN 1166372C CN B991131835 A CNB991131835 A CN B991131835A CN 99113183 A CN99113183 A CN 99113183A CN 1166372 C CN1166372 C CN 1166372C
- Authority
- CN
- China
- Prior art keywords
- milliliters
- grams
- medicine
- borneolum syntheticum
- rhizoma corydalis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a medicine for treating myopia and a preparation method thereof. The medicine of the present invention is prepared from semen cassiae, decumbent corydalis tuber, borneol and pearl hydrolysate. The preparation method comprises: a. 800 to 1800g of the semen cassiae is decocted for three times; b. 2800 to 3500g of decumbent corydalis tuber is decocted for three times; c. filtrates of the two traditional Chinese medicines are merged, the mixture is concentrated to 500 to 600 milliliters; d. 800 to 5000g of the borneol is heated to the temperature of 205 to 210 DEG C to prepare borneol hydrolysate, and 100 to 1000 milliliters of the pearl hydrolysate is extracted by a conventional method; e. the borneol hydrolysate and the pearl hydrolysate are respectively added to the medicine liquor, the medicine liquor is made to stand and is filtered, and then 14000 milliliters of distilled water is added. The medicine of the present invention can relieve eyesight tension and improve eyesight fatigue, and has the function of health care.
Description
Technical field
The present invention relates to medicament for the eyes, Chinese medicine collyrium of specifically a kind of adolescent myopia prevention and health care and preparation method thereof.
Background technology
The generation of adolescent myopia is the hot issue of social common concern always.Nineteen ninety-five, national teenager body constitution investigation shows that national teenager visual disturbance rate and near-sighted incidence rate are still high; In August, 1991, in the health care opinion side public lecture of Huhehaote whole nation school hygiene, Harbin City Education Commission to 1973～1991 years 18 years student eyesight tracking findings of the survey in the Harbin City five is: enter a school newborn rate of myopia from 1973 12.6% rise to 1991 59.7%; The seventies, average rate of myopia was 16.7%; Be 39.7% the eighties; The nineties, (91 years) were 56.7%.Even more serious is: teenager visual disturbance prevalence allows the people surprised especially, nineteen ninety, Wuxi City Education Commission was to 1457 student eyesight investigation of the beautiful Qi Zhongxue of Wuxi City, find the low sickness rate 55% of a high student eyesight, Senior Two, Senior Three visual disturbance rate are up to more than 70%.The severe fact has caused the scientific research personnel's of government and numerous strong-willed student eyesight health care researchs concern, in the prior art, people make collyrium with the Chinese medicine Rhizoma Corydalis Decumbentis, the treatment juvenile myopia, a lot of reports were arranged successively from the seventies, for example: People's Health Publisher's " few hygiology of youngster " Tang Xilin chief editor, respectful the continuing of leaf checked in " rescuing of myopia " chapter, point out: " the Chinese medicine Guttae Rhizoma Corydalis Decumbentis it is reported certain curative effect." for another example: 1984; Shandong Province's epidemic prevention station " Shandong epidemic prevention " magazine second phase is reported Teng county, Shandong Province epidemic prevention station Zhu Xumin article: " life-time service Guttae Rhizoma Corydalis Decumbentis treatment students in middle and primary schools pseudomyopia observation of curative effect "; 12 phases of nineteen eighty-three " safe and comfortable preventive medicine " the magazine report Xunyang County Yang Ping of health and epidemic prevention station gift article " the nearly fogging method of eyes; Rhizoma Corydalis Decumbentis; collyrium such as neostigmine methylsulfate treatment students in middle and primary schools pseudomyopia 146 routine effect observations "; " area, Wuzhou health " 12 phases of magazine nineteen eighty-three are reported the article " Rhizoma Corydalis Decumbentis of the Zhongshan County Dong of health and epidemic prevention station foundation, the vitamin K3 collyrium is treated bathomorphic preliminary brief summary ", Hubei Province Society of Ophthalmology first academic conference in March nineteen eighty-three report Jingmen oil plant worker's hospital is " about mineral spring, 654-2, collyrium such as Rhizoma Corydalis Decumbentis treatment juvenile myopia effect observation ", existing in addition is most Borneolum Syntheticum adapteds of using in the agent.Although the vision that relevant department, society take various measures to protect young people, because the treatment way is single, curative effect is also pessimistic.
Summary of the invention
In order to overcome above-mentioned deficiency, the invention provides and a kind ofly can alleviate the vision anxiety, improve asthenopia, reach the prevention of vision care effect and treat bathomorphic medicine and preparation method thereof.
To achieve these goals, technical scheme of the present invention is: it is to be made by following raw materials according: Semen Cassiae 800～1800 grams, Rhizoma Corydalis Decumbentis 2800～3500 grams, Borneolum Syntheticum 800～5000 grams, 100～1000 milliliters of Margarita hydrolyzed solutions.
The preparation method of medicine of the present invention is carried out as follows:
A. depend on pine torch 800～1800 grams, decoct 3 times;
B. get Rhizoma Corydalis Decumbentis 2800～3500 grams, decoct 3 times;
C. merge above-mentioned two kinds of Chinese medicine filtrate, be concentrated into 500～600 milliliters;
D. get Borneolum Syntheticum 800～5000 grams, heat 205～210 ℃, make the Borneolum Syntheticum hydrolyzed solution; Extract 100～1000 milliliters of Margarita hydrolyzed solutions according to a conventional method;
E. respectively Borneolum Syntheticum hydrolyzed solution and Margarita hydrolyzed solution are added in the herb liquid.
The above-mentioned medicinal liquid that makes was left standstill 2～14 hours; Filter then, in filtration, add the convention amount antibacterial, 180～220 milliliters of solubilizing agents, buffer is reconciled pH value to 6.0～8.0, and isosmotic solution, reconciles osmotic pressure to 0.8～1.2%; Adding distil water is 14000 milliliters again.
The present invention has following advantage:
The present invention is owing to adopt Semen Cassiae, Rhizoma Corydalis Decumbentis, Borneolum Syntheticum and Margarita hydrolyzed solution to form prescription with special method simultaneously, can be in axial myopia (true myopia) morbidity or before and after functional myopia (pseudomyopia) takes place as yet, in time alleviate, regulate eye ciliary muscle high-pressure state, vision is improved and recover, and can treat functional myopia (vision is before 4.6), through clinical experiment, good effect.
The specific embodiment
Below in conjunction with embodiment the present invention is described in further detail.
Embodiment
Medicine of the present invention is made by following raw materials according: Semen Cassiae 800 grams, Rhizoma Corydalis Decumbentis 2800 grams, Borneolum Syntheticum 800 grams, 100 milliliters of Margarita hydrolyzed solutions.
The present invention selects Rhizoma Corydalis Decumbentis, Borneolum Syntheticum, Semen Cassiae, four kinds of Chinese herbal medicine of Margarita on hundred kinds of motherland Chinese medicine bases of Compendium of Material Medica equivalence, its performance is as follows:
Semen Cassiae: it is top grade that Semen Cassiae is listed in Shennong's Herbal, the Tao Hongjing meaning: " leaf such as cyperus sesame, the likeness in form Horse hoof exhales to be the Horse hoof Semen Cassiae ", " working as of using smashed to pieces "; Li Mingzhen thinks " with the merit that makes eye bright name ".Semen Cassiae, salty, flat; Go into liver, large intestine channel.Semen Cassiae function: make eye bright, liver heat removing, intestine moistening.Semen Cassiae composition: mainly contain chrysophanol.Its pharmacological action: its water logging agent and ethanol preserved material all have hypotensive effect to anesthesia Canis familiaris L., cat.Its consideration acts on eyelash shape muscular nerve level anesthetic action, may be to the eyelash shape muscle tonus that relaxes, and alleviating the eyestrain has effect.
Borneolum Syntheticum: have another name called Flos Mume brain, Borneolum Syntheticum, Borneolum Syntheticum is stated from Tang Materia Medica, Li Mingzhen meaning: " the Borneolum Syntheticum person, because of its shape such as valuable title also, good with Bai Yingru ice and Flos Mume sheet person, be the Borneolum Syntheticum brain so custom is exhaled, or cloud Flos Mume brain." Borneolum Syntheticum, suffering, hardship, be slightly cold into the heart spleen channel.Borneolum Syntheticum function: make eye bright removing nebula, the stagnated fire of loosing, logical all keys, reducing swelling and alleviating pain.Borneolum Syntheticum composition: be d-Borneolum Syntheticum." Chinese herbology " goes up pharmacology and indicates: clinical curing mainly, conjunctival congestion cataracta.
Rhizoma Corydalis Decumbentis: this product is that the tuber of bloodroot Hotseason grow contains corydaline, protopine etc.Its pharmacological action: Rhizoma Corydalis Decumbentis 0.5～1.0 gram/kilogram, to anesthetized cat have more obviously, more persistent hypotensive activity.Performance: hardship, cold, blood pressure lowering, pain relieving, promoting flow of QI and blood.Clinical curing mainly: 1. blood pressure lowering, 2. hemiplegia, 3. rheumatism, 4. lumbar muscle strain.Its dominant mechanism: think to make effectively eyelash shape muscular nerve to anaesthetize, make and regulate paralysis, thereby an eye ciliary muscle that is in high-pressure adjustment state, long-term anxiety, generation spasm is loosened, alleviate the eyestrain, and then obtain the vision protection effect.
Margarita hydrolyzed solution: Margarita property, sweet, cold, heat clearing away has effect to conjunctival congestion, mist barrier.
The preparation method detailed process of above-mentioned prescription is as follows:
Take by weighing Semen Cassiae 800 grams earlier, clean, 1500 milliliters of each adding distil waters decoct 3 times, leave standstill 10 hours, filter; Get Rhizoma Corydalis Decumbentis 2800 grams again, clean,, decoct 3 times, left standstill 10 hours, filter at every turn as 4000 milliliters of distilled water; Merge above-mentioned two kinds of filtrates, 600 milliliters of system concentrated solutions; Get Borneolum Syntheticum 800 gram and be heated to 205 ℃ and make 100 milliliters of Borneolum Syntheticum aqueous solutions, add in the described filtrate; Get 100 milliliters of Margarita hydrolyzed solutions, add in the described filtrate; Filter, behind 50 milliliters of phenoxyethanol antibacterial of adding, add 150 milliliters of Tween 80 solubilizing agents in the filtrate, add an amount of phosphate buffer again and reconcile pH value to 7.0, and then add sodium chloride isosmotic solution conciliation osmotic pressure to 0.9%; Last adding distil water is made 15000 milliliters of prescriptions for 14000 milliliters, under 100 degrees centigrade, sterilized 30 minutes.15 milliliters every bottle, make 1000 bottles.
Claims (3)
- One kind the prevention and treat bathomorphic medicine, it is characterized in that: it is made by following raw materials according:Semen Cassiae 800～1800 grams, Rhizoma Corydalis Decumbentis 2800～3500 grams, Borneolum Syntheticum 800～5000 grams, 100～1000 milliliters of Margarita hydrolyzed solutions.
- 2. preparation method according to the described medicine of claim 1 is characterized in that carrying out as follows:A. depend on pine torch 800～1800 grams, decoct 3 times;B. get Rhizoma Corydalis Decumbentis 2800～3500 grams, decoct 3 times;C. merge above-mentioned two kinds of Chinese medicine filtrate, be concentrated into 500～600 milliliters;D. get Borneolum Syntheticum 800～5000 grams, heat 205～210 ℃, make the Borneolum Syntheticum hydrolyzed solution; Extract 100～1000 milliliters of Margarita hydrolyzed solutions according to a conventional method;E. respectively Borneolum Syntheticum hydrolyzed solution and Margarita hydrolyzed solution are added in the herb liquid.
- 3. according to the described preparation method of claim 2, it is characterized in that: the medicinal liquid that claim 2 is made left standstill 2～10 hours; Filter then, in filtration, add the convention amount antibacterial, 180～220 milliliters of solubilizing agents, buffer is reconciled pH value to 6.0～8.0, and isosmotic solution, reconciles osmotic pressure to 0.8～1.2%; Adding distil water is 14000 milliliters again.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB991131835A CN1166372C (en) | 1999-08-23 | 1999-08-23 | Formula of medicine for treating myopia and preparation process thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB991131835A CN1166372C (en) | 1999-08-23 | 1999-08-23 | Formula of medicine for treating myopia and preparation process thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1285211A CN1285211A (en) | 2001-02-28 |
| CN1166372C true CN1166372C (en) | 2004-09-15 |
Family
ID=5276401
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB991131835A Expired - Fee Related CN1166372C (en) | 1999-08-23 | 1999-08-23 | Formula of medicine for treating myopia and preparation process thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1166372C (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1302765C (en) * | 2003-12-16 | 2007-03-07 | 上海卫康光学有限公司 | Ophthalmic solution containing borneol and usage thereof |
| CN111000912A (en) * | 2019-12-18 | 2020-04-14 | 河南中医药大学 | External use Qingqinghua essential oil for treating myopia |
| CN113768965A (en) * | 2021-09-23 | 2021-12-10 | 重庆视健眼健康产业有限公司 | Borneol eye spray |
-
1999
- 1999-08-23 CN CNB991131835A patent/CN1166372C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1285211A (en) | 2001-02-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102139038A (en) | Chinese herbal preparation for treating eye diseases | |
| CN104288334A (en) | Traditional Chinese medicine eye drop for relieving eyestrain and preparation method thereof | |
| CN103393969B (en) | Eye drop used for releasing eye fatigue and preparation method thereof | |
| CN102657739A (en) | Eyesight adjusting ointment for myopia | |
| CN100364593C (en) | Oral liquid for promoting eyesight and protecting eye | |
| CN1166372C (en) | Formula of medicine for treating myopia and preparation process thereof | |
| CN111558031B (en) | Pure plant multifunctional eye special nutrient solution and preparation method thereof | |
| CN101284048A (en) | Formulations for effectively improving hypometropia, asthenopia, cataract, eyeground pathological changes | |
| CN110934925A (en) | Traditional Chinese medicine composition of eye patch for relieving asthenopia | |
| CN110859895A (en) | Eye ointment and preparation method thereof | |
| CN109010652A (en) | A kind of Chinese herb medicine eye application and production method | |
| CN110269895A (en) | A kind of visual rehabilitation Chinese medicine composition containing fresh Chinese medicine and preparation method thereof, preparation | |
| CN108785365A (en) | A kind of eyedrops for treating myopia | |
| CN104815155A (en) | Traditional Chinese medicine drops capable of expelling wind, relieving itching and improving eyesight | |
| CN112220877B (en) | Traditional Chinese medicine preparation for treating cerebral apoplexy in convalescent period and preparation method thereof | |
| CN103550357B (en) | A kind of control muscae volitantes collyrium and its production and use | |
| CN114712443B (en) | Traditional Chinese medicine fermentation composition, refreshing and restoring consciousness condensation and preparation method thereof | |
| CN1073600A (en) | The preparation method of the Chinese medicine preparation of treatment pseudomyopia | |
| CN103405649B (en) | External pharmaceutical composition for recovery after nervus peroneus communis injury | |
| AU2020101678A4 (en) | A health care drink and preparation method thereof | |
| CN104739991B (en) | A kind of Chinese medicine for treating sty | |
| CN100400070C (en) | Externally applied medicine for treating dermatosis and preparation method thereof | |
| CN1068215C (en) | Pasting preparation for eliminating pain | |
| CN1079392A (en) | Method for preparing yulelu emulsion | |
| CN105726767A (en) | Traditional Chinese medicine eye drops for easing eye strain and preparation method of traditional Chinese medicine eye drops |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |