CN116570535A - Female private care solution and preparation method thereof - Google Patents
Female private care solution and preparation method thereof Download PDFInfo
- Publication number
- CN116570535A CN116570535A CN202310642093.7A CN202310642093A CN116570535A CN 116570535 A CN116570535 A CN 116570535A CN 202310642093 A CN202310642093 A CN 202310642093A CN 116570535 A CN116570535 A CN 116570535A
- Authority
- CN
- China
- Prior art keywords
- carbomer
- female private
- further improvement
- sodium hydroxide
- parts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 10
- 229920002125 Sokalan® Polymers 0.000 claims abstract description 20
- XVPBINOPNYFXID-JARXUMMXSA-N 85u4c366qs Chemical compound C([C@@H]1CCC[N@+]2(CCC[C@H]3[C@@H]21)[O-])N1[C@@H]3CCCC1=O XVPBINOPNYFXID-JARXUMMXSA-N 0.000 claims abstract description 17
- 239000007788 liquid Substances 0.000 claims abstract description 11
- 229930015582 oxymatrine Natural products 0.000 claims abstract description 10
- 230000000474 nursing effect Effects 0.000 claims abstract description 9
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 33
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 15
- 229960001631 carbomer Drugs 0.000 claims description 15
- 239000008367 deionised water Substances 0.000 claims description 10
- 229910021641 deionized water Inorganic materials 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 230000000844 anti-bacterial effect Effects 0.000 claims description 9
- 230000006872 improvement Effects 0.000 claims description 9
- 239000000463 material Substances 0.000 claims description 9
- 230000003110 anti-inflammatory effect Effects 0.000 claims description 8
- PPASLZSBLFJQEF-RKJRWTFHSA-M sodium ascorbate Substances [Na+].OC[C@@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RKJRWTFHSA-M 0.000 claims description 8
- 235000010378 sodium ascorbate Nutrition 0.000 claims description 8
- 229960005055 sodium ascorbate Drugs 0.000 claims description 8
- PPASLZSBLFJQEF-RXSVEWSESA-M sodium-L-ascorbate Chemical compound [Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RXSVEWSESA-M 0.000 claims description 8
- 238000003756 stirring Methods 0.000 claims description 6
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims description 4
- 238000006386 neutralization reaction Methods 0.000 claims description 4
- 239000000686 essence Substances 0.000 claims description 3
- 229940083608 sodium hydroxide Drugs 0.000 claims description 3
- 230000008719 thickening Effects 0.000 claims description 3
- SLAMLWHELXOEJZ-UHFFFAOYSA-M 2-nitrobenzoate Chemical compound [O-]C(=O)C1=CC=CC=C1[N+]([O-])=O SLAMLWHELXOEJZ-UHFFFAOYSA-M 0.000 claims description 2
- FJKROLUGYXJWQN-UHFFFAOYSA-M 4-hydroxybenzoate Chemical compound OC1=CC=C(C([O-])=O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-M 0.000 claims description 2
- VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 claims description 2
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 claims description 2
- 229910021529 ammonia Inorganic materials 0.000 claims description 2
- -1 nipagin ester Chemical class 0.000 claims description 2
- 239000003755 preservative agent Substances 0.000 claims description 2
- 230000002335 preservative effect Effects 0.000 claims description 2
- 239000001632 sodium acetate Substances 0.000 claims description 2
- 235000017281 sodium acetate Nutrition 0.000 claims description 2
- 239000002562 thickening agent Substances 0.000 claims description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 4
- 239000000377 silicon dioxide Substances 0.000 claims 2
- 229910021502 aluminium hydroxide Inorganic materials 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000002131 composite material Substances 0.000 claims 1
- 230000003750 conditioning effect Effects 0.000 claims 1
- 239000004005 microsphere Substances 0.000 claims 1
- 230000003472 neutralizing effect Effects 0.000 claims 1
- 235000012239 silicon dioxide Nutrition 0.000 claims 1
- 229920002050 silicone resin Polymers 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 7
- 206010061218 Inflammation Diseases 0.000 abstract description 5
- 230000004054 inflammatory process Effects 0.000 abstract description 5
- 241000894006 Bacteria Species 0.000 abstract description 3
- 230000036541 health Effects 0.000 abstract description 2
- 239000000419 plant extract Substances 0.000 abstract description 2
- 239000000853 adhesive Substances 0.000 abstract 1
- 230000001070 adhesive effect Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 230000007794 irritation Effects 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- 238000004659 sterilization and disinfection Methods 0.000 description 3
- 235000005976 Citrus sinensis Nutrition 0.000 description 2
- 240000002319 Citrus sinensis Species 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 230000000259 anti-tumor effect Effects 0.000 description 2
- 230000003078 antioxidant effect Effects 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 210000004881 tumor cell Anatomy 0.000 description 2
- MIJYXULNPSFWEK-GTOFXWBISA-N 3beta-hydroxyolean-12-en-28-oic acid Chemical compound C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CCC(C)(C)C[C@H]5C4=CC[C@@H]3[C@]21C MIJYXULNPSFWEK-GTOFXWBISA-N 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 206010027476 Metastases Diseases 0.000 description 1
- MIJYXULNPSFWEK-UHFFFAOYSA-N Oleanolinsaeure Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)(C)CC5C4=CCC3C21C MIJYXULNPSFWEK-UHFFFAOYSA-N 0.000 description 1
- 208000028990 Skin injury Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 230000003276 anti-hypertensive effect Effects 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 230000006907 apoptotic process Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 230000004531 blood pressure lowering effect Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000005802 health problem Effects 0.000 description 1
- 230000002519 immonomodulatory effect Effects 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 230000009401 metastasis Effects 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 230000004792 oxidative damage Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention relates to a female private care solution and a preparation method thereof. The oxymatrine is a natural plant extract, has various effects of resisting bacteria, inflammation, oxidization and the like, and can effectively prevent and treat various problems of female private users; carbomers are a commonly used water-soluble adhesive that can improve the viscosity and stability of the care solution. The nursing liquid has good nursing effect and can effectively protect the health of female private users.
Description
Technical Field
The invention relates to the field of female private care, in particular to female private care solution composed of matrine oxide and carbomer solution and a preparation method thereof.
Background
With the development of society and the improvement of living standard of people, the health problem of female private users is more and more concerned. However, the traditional nursing method for female private users has some defects, such as excessive use of medicines, incomplete cleaning and the like, and the infection and other problems of the female private users are easily caused.
The invention aims to solve the technical problems of providing the antibacterial and anti-inflammatory liquid for female private users, which has the advantages of small irritation, small skin injury, difficult skin allergy, difficult secondary injury, basically no peculiar smell, good use experience, thorough sterilization and bacteriostasis effect, difficult inflammation generation and basically no influence on the life and work of females, and the preparation process.
Disclosure of Invention
Existing feminine private care solutions are typically composed of a single component, such as a cleanser, antimicrobial agent, etc., and lack a comprehensive solution to the problem of the female private. Moreover, the use method and the dosage of the nursing liquid are not scientific and reasonable enough, and the nursing liquid is difficult to meet the nursing demands of female private users.
As a further improvement to the present invention, specific models of carbomers are also included, including carbomer ERD2020, carbomers 940, 910, 934P, 940, 941, 954.
As a further improvement of the invention, the sodium hydroxide can also be replaced by ammonia, aluminum hydroxide, sodium acetate as a neutralization thickening agent.
As a further improvement of the invention, the sodium ascorbate has a preservative function and can be replaced by parahydroxybenzoate, nipagin ester and nitrobenzoate.
As a further improvement of the invention, the skin conditioner is a mixture of medicinal layer porus extract, sweet orange peel oil, octanoylglycine and caryophyllin.
A preparation process of antibacterial and anti-inflammatory liquid for female private users comprises the following steps of 1) preparing materials: matrine oxide, carbomer, sodium hydroxide, sodium ascorbate, essence, skin conditioner and deionized water; 2) Preparing a base material: stirring carbomer and deionized water for 300min; 3) Adding the rest components of the materials prepared in the step 1) into the system of the previous step, and uniformly stirring; 4) Neutralization thickening: adding sodium hydroxide into the system of 3) gradually and slightly to make the pH value of the system be about 7, so as to form a finished product with viscosity.
The invention has the beneficial effects that: the nursing liquid has good nursing effect and can effectively protect the health of female private users. The medical care solution adopts two natural plant extracts of matrine oxide and carbomer solution, has no side effect, has no irritation to the skin of female private, and can improve the viscosity and stability of the care solution so that the care solution is easier to be absorbed by the skin of female private.
Detailed Description
In order to better understand the technical content of the present invention, the following specific examples are provided to further illustrate the present invention.
The properties of the main pharmaceutical ingredients of the invention are known in the art as follows:
oxymatrine:
antibacterial action: the oxymatrine has the effect of inhibiting the growth of various bacteria, fungi and viruses, and particularly has good inhibiting effect on some drug-resistant bacteria.
Anti-inflammatory action: the oxymatrine can inhibit the occurrence and development of inflammatory reaction, reduce the level of inflammatory mediators, and relieve inflammation symptoms and pathological injury.
Antioxidant effect: the oxymatrine has strong antioxidant activity, and can remove free radicals and protect cells from oxidative damage.
Antihypertensive effect: the oxymatrine can dilate blood vessel, reduce blood pressure, and has certain blood pressure lowering effect.
Antitumor effect: the oxymatrine can inhibit proliferation and metastasis of tumor cells, promote apoptosis of tumor cells, and has certain antitumor effect.
Immunomodulatory effects: the oxymatrine can regulate the function of immune system and enhance immunity.
Example 1
The antibacterial and anti-inflammatory liquid for female private users comprises, by weight, 1 part of matrine oxide, 1 part of carbomer, 0.2 part of sodium hydroxide, 0.5 part of sodium ascorbate, 0.58 part of essence, 0.54 part of skin conditioner and 200 parts of deionized water.
In the embodiment, each component is a range value, and the sum of the components in the range is combined and matched according to 100 parts, so that the antibacterial effect can reach more than 95%, various additive preparations are adopted and deionized water is used, the irritation is small, no peculiar smell is generated basically, and the use effect is good.
Example 2
Wherein, the specific proportion of each ingredient is as follows: 1 part of oxymatrine, 0.2 part of carbomer, 0.2 part of sodium hydroxide, 0.5 part of sodium ascorbate, 0.58 part of essence, 0.54 part of skin conditioner and 150 parts of deionized water.
The components in the embodiment are a specific value, the specific component has the best effect, the antibacterial effect can reach 98 percent, the sterilization and antibacterial effect of the existing sterilization and anti-inflammatory products such as the gynecological inflammation cleaner is basically between 80 and 85 percent, the effect is not ideal, and the effect is obvious by using the anti-inflammatory liquid in the embodiment 2.
In the invention, the skin conditioner is a mixture of medicinal layer porus extract, sweet orange peel oil, octanoylglycine and caryophyllus.
A preparation process of antibacterial and anti-inflammatory liquid for female private users comprises the following steps of 1) preparing materials: matrine oxide, carbomer, sodium hydroxide, sodium ascorbate, essence, skin conditioner and deionized water; 2) Preparing a base material: stirring carbomer and deionized water for 300min; 3) Adding the rest components of the materials prepared in the step 1) into the system of the previous step, and uniformly stirring; 4) Neutralization thickening: adding sodium hydroxide into the system of 3) gradually and slightly to make the pH value of the system be 6.98, so as to form a finished product with viscosity.
Claims (6)
1. The invention provides a female private care solution composed of matrine oxide and carbomer solution and a preparation method thereof. The nursing liquid consists of the following components in parts by weight: 1-3 parts of oxymatrine, 1-5 parts of carbomer, 0.1-0.5 part of sodium hydroxide, 0.1-0.5 part of sodium ascorbate, 0.05-0.1 part of essence, 0.5-1 part of skin conditioner and 100-200 parts of deionized water.
2. According to claim 1, as a further improvement of the invention, a specific model of carbomers is also included, said carbomer model including carbomer ERD2020, carbomers 940, 910, 934P, 940, 941, 954.
3. According to claim 1, as a further improvement of the invention, the sodium hydroxide as neutralizing and thickening agent can also be replaced by ammonia, aluminium hydroxide, sodium acetate.
4. According to claim 1, as a further improvement of the invention, the sodium ascorbate has a preservative function and can be replaced by parahydroxybenzoate, nipagin ester and nitrobenzoate.
5. According to claim 1, as a further improvement of the invention, the skin conditioning agent is medicinal silicone resin, silica, composite microsphere or silicon dioxide.
6. A preparation process of antibacterial and anti-inflammatory liquid for female private users comprises the following steps of 1) preparing materials: matrine oxide, carbomer, sodium hydroxide, sodium ascorbate, essence, skin conditioner and deionized water; 2) Preparing a base material: stirring carbomer and deionized water for 300min; 3) Adding the rest components of the materials prepared in the step 1) into the system of the previous step, and uniformly stirring; 4) Neutralization thickening: adding sodium hydroxide into the system of 3) gradually and slightly to make the pH value of the system be about 7, so as to form a finished product with viscosity.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310642093.7A CN116570535A (en) | 2023-06-01 | 2023-06-01 | Female private care solution and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310642093.7A CN116570535A (en) | 2023-06-01 | 2023-06-01 | Female private care solution and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116570535A true CN116570535A (en) | 2023-08-11 |
Family
ID=87543072
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202310642093.7A Pending CN116570535A (en) | 2023-06-01 | 2023-06-01 | Female private care solution and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN116570535A (en) |
-
2023
- 2023-06-01 CN CN202310642093.7A patent/CN116570535A/en active Pending
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| PB01 | Publication | ||
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| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |