CN116555237A - 胞嘧啶脱氨酶及其在碱基编辑中的用途 - Google Patents
胞嘧啶脱氨酶及其在碱基编辑中的用途 Download PDFInfo
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- CN116555237A CN116555237A CN202310220057.1A CN202310220057A CN116555237A CN 116555237 A CN116555237 A CN 116555237A CN 202310220057 A CN202310220057 A CN 202310220057A CN 116555237 A CN116555237 A CN 116555237A
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- cytosine deaminase
- protein
- sequence
- cytosine
- base editing
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202511062015.5A CN120944860A (zh) | 2022-03-08 | 2023-03-07 | 胞嘧啶脱氨酶及其在碱基编辑中的用途 |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210220832 | 2022-03-08 | ||
| CN2022102208329 | 2022-03-08 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202511062015.5A Division CN120944860A (zh) | 2022-03-08 | 2023-03-07 | 胞嘧啶脱氨酶及其在碱基编辑中的用途 |
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| Publication Number | Publication Date |
|---|---|
| CN116555237A true CN116555237A (zh) | 2023-08-08 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202310220057.1A Pending CN116555237A (zh) | 2022-03-08 | 2023-03-07 | 胞嘧啶脱氨酶及其在碱基编辑中的用途 |
| CN202511062015.5A Pending CN120944860A (zh) | 2022-03-08 | 2023-03-07 | 胞嘧啶脱氨酶及其在碱基编辑中的用途 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202511062015.5A Pending CN120944860A (zh) | 2022-03-08 | 2023-03-07 | 胞嘧啶脱氨酶及其在碱基编辑中的用途 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20250263684A1 (https=) |
| EP (1) | EP4491723A1 (https=) |
| JP (1) | JP2025510586A (https=) |
| KR (1) | KR20250007507A (https=) |
| CN (2) | CN116555237A (https=) |
| WO (1) | WO2023169410A1 (https=) |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116721700A (zh) * | 2023-08-08 | 2023-09-08 | 中国人民解放军军事科学院军事医学研究院 | 鉴定新型双链dna胞苷脱氨酶的方法、装置和计算机可读存储介质及应用 |
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| CN119913132A (zh) * | 2024-06-17 | 2025-05-02 | 中国农业大学 | 胞嘧啶脱氨酶及其相关生物材料与应用 |
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| CN121065143A (zh) * | 2022-12-15 | 2025-12-05 | 中国科学院遗传与发育生物学研究所 | 一种碱基编辑器及其应用 |
| WO2025260911A1 (zh) * | 2024-06-17 | 2025-12-26 | 中国农业大学 | 单碱基编辑器及其所用脱氨酶与应用 |
| CN121237206A (zh) * | 2024-09-19 | 2025-12-30 | 中国科学院遗传与发育生物学研究所 | 一种基于人工智能的酶工程方法、系统、设备及介质 |
| CN121065143B (en) * | 2022-12-15 | 2026-05-05 | 中国科学院遗传与发育生物学研究所 | Base editor and application thereof |
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| CN117659210A (zh) * | 2023-11-30 | 2024-03-08 | 华南农业大学 | 一种用作植物双碱基编辑器的重组融合蛋白及其应用 |
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| CN121518574B (zh) * | 2026-01-14 | 2026-04-24 | 中国农业科学院北京畜牧兽医研究所 | 胞嘧啶碱基编辑器介导的猪zscan4基因敲除方法及体系和应用 |
| CN121555485B (zh) * | 2026-01-21 | 2026-04-24 | 中国农业大学 | 源于宏基因组挖掘的胞嘧啶脱氨酶及其生物材料与应用 |
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| CN121065143A (zh) * | 2022-12-15 | 2025-12-05 | 中国科学院遗传与发育生物学研究所 | 一种碱基编辑器及其应用 |
| CN121065143B (en) * | 2022-12-15 | 2026-05-05 | 中国科学院遗传与发育生物学研究所 | Base editor and application thereof |
| CN116721700A (zh) * | 2023-08-08 | 2023-09-08 | 中国人民解放军军事科学院军事医学研究院 | 鉴定新型双链dna胞苷脱氨酶的方法、装置和计算机可读存储介质及应用 |
| CN116721700B (zh) * | 2023-08-08 | 2024-01-12 | 中国人民解放军军事科学院军事医学研究院 | 鉴定新型双链dna胞苷脱氨酶的方法、装置及应用 |
| WO2025045079A1 (zh) * | 2023-08-29 | 2025-03-06 | 苏州湃芮生物科技有限公司 | 一种基于rna特异性脱氨酶突变体及其应用 |
| WO2025119307A1 (zh) * | 2023-12-06 | 2025-06-12 | 北京齐禾生科生物科技有限公司 | 优化的qbe碱基编辑系统及其应用 |
| CN120818512A (zh) * | 2024-04-11 | 2025-10-21 | 上海交通大学医学院附属松江医院 | 一种工程化胞嘧啶脱氨酶及其制备方法和用途 |
| CN119913132A (zh) * | 2024-06-17 | 2025-05-02 | 中国农业大学 | 胞嘧啶脱氨酶及其相关生物材料与应用 |
| WO2025260911A1 (zh) * | 2024-06-17 | 2025-12-26 | 中国农业大学 | 单碱基编辑器及其所用脱氨酶与应用 |
| CN121237206A (zh) * | 2024-09-19 | 2025-12-30 | 中国科学院遗传与发育生物学研究所 | 一种基于人工智能的酶工程方法、系统、设备及介质 |
| CN119517174A (zh) * | 2024-10-28 | 2025-02-25 | 南京大学 | 基于进化生物学与计算生物的rna进化前体筛选方法 |
| CN119286832A (zh) * | 2024-10-30 | 2025-01-10 | 安徽农业大学 | 一种胞嘧啶脱氨酶突变体及其碱基编辑系统和应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2023169410A1 (zh) | 2023-09-14 |
| CN120944860A (zh) | 2025-11-14 |
| US20250263684A1 (en) | 2025-08-21 |
| JP2025510586A (ja) | 2025-04-15 |
| KR20250007507A (ko) | 2025-01-14 |
| EP4491723A1 (en) | 2025-01-15 |
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