CN116547375A8 - 用于生物处理系统的热传递和质量传递的系统和方法 - Google Patents

用于生物处理系统的热传递和质量传递的系统和方法 Download PDF

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Publication number
CN116547375A8
CN116547375A8 CN202180083853.4A CN202180083853A CN116547375A8 CN 116547375 A8 CN116547375 A8 CN 116547375A8 CN 202180083853 A CN202180083853 A CN 202180083853A CN 116547375 A8 CN116547375 A8 CN 116547375A8
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CN
China
Prior art keywords
systems
biological treatment
methods
heat
mass transfer
Prior art date
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Pending
Application number
CN202180083853.4A
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English (en)
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CN116547375A (zh
Inventor
A·丰托瓦索萨
M·蒂明斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Globegroup Life Technology Consulting America Co ltd
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Globegroup Life Technology Consulting America Co ltd
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Application filed by Globegroup Life Technology Consulting America Co ltd filed Critical Globegroup Life Technology Consulting America Co ltd
Publication of CN116547375A publication Critical patent/CN116547375A/zh
Publication of CN116547375A8 publication Critical patent/CN116547375A8/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/14—Incubators; Climatic chambers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/24—Gas permeable parts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/40—Manifolds; Distribution pieces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/44—Multiple separable units; Modules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/16—Vibrating; Shaking; Tilting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/20—Degassing; Venting; Bubble traps
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Immunology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)

Abstract

一种生物处理方法包括以下步骤：提供具有气体可渗透、液体不可渗透的膜的生物反应器容器；启动气体流；以及使气体流横跨膜的底表面通过，以诱导气体流和膜之间的湍流相互作用。
CN202180083853.4A 2020-12-15 2021-12-14 用于生物处理系统的热传递和质量传递的系统和方法 Pending CN116547375A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063125870P 2020-12-15 2020-12-15
US63/125,870 2020-12-15
PCT/US2021/063285 WO2022132751A1 (en) 2020-12-15 2021-12-14 System and method for heat and mass transfer for a bioprocessing system

Publications (2)

Publication Number Publication Date
CN116547375A CN116547375A (zh) 2023-08-04
CN116547375A8 true CN116547375A8 (zh) 2023-09-01

Family

ID=80112306

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180083853.4A Pending CN116547375A (zh) 2020-12-15 2021-12-14 用于生物处理系统的热传递和质量传递的系统和方法

Country Status (7)

Country Link
US (1) US20240034971A1 (zh)
EP (1) EP4263788A1 (zh)
JP (1) JP2024500371A (zh)
KR (1) KR20230119643A (zh)
CN (1) CN116547375A (zh)
CA (1) CA3201296A1 (zh)
WO (1) WO2022132751A1 (zh)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6455310B1 (en) * 1999-03-23 2002-09-24 Biocrystal Ltd. Cell culture apparatus and method for culturing cells
DE102013013665B4 (de) * 2013-08-16 2015-12-03 Thermo Electron Led Gmbh Laboratoriumsbrutschrank mit verbesserter Feuchtigkeitseinstellung
JP7350741B2 (ja) 2017-12-01 2023-09-26 グローバル・ライフ・サイエンシズ・ソリューションズ・ユーエスエー・エルエルシー 細胞濃縮および単離のための方法
US20200238282A1 (en) 2019-01-24 2020-07-30 Ge Healthcare Bio-Sciences Corp. Fluid handling apparatus for a bioprocessing system

Also Published As

Publication number Publication date
US20240034971A1 (en) 2024-02-01
CN116547375A (zh) 2023-08-04
WO2022132751A1 (en) 2022-06-23
CA3201296A1 (en) 2022-06-23
JP2024500371A (ja) 2024-01-09
EP4263788A1 (en) 2023-10-25
KR20230119643A (ko) 2023-08-16

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Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
CI02 Correction of invention patent application
CI02 Correction of invention patent application

Correction item: Priority

Correct: 63/125,870 2020.12.15 US

Number: 31-02

Page: The title page

Volume: 39

Correction item: Priority

Correct: 63/125,870 2020.12.15 US

Number: 31-02

Volume: 39

SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination