CN116500253A - Mixing and sample adding assembly of incubation module of immunity quantitative analyzer - Google Patents
Mixing and sample adding assembly of incubation module of immunity quantitative analyzer Download PDFInfo
- Publication number
- CN116500253A CN116500253A CN202310783897.9A CN202310783897A CN116500253A CN 116500253 A CN116500253 A CN 116500253A CN 202310783897 A CN202310783897 A CN 202310783897A CN 116500253 A CN116500253 A CN 116500253A
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- plate
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- swing
- seat
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- 238000011534 incubation Methods 0.000 title claims abstract description 168
- 238000002156 mixing Methods 0.000 title claims abstract description 30
- 230000036039 immunity Effects 0.000 title claims abstract description 10
- 230000007246 mechanism Effects 0.000 claims abstract description 56
- 239000007788 liquid Substances 0.000 claims abstract description 22
- 238000003825 pressing Methods 0.000 claims description 30
- 230000003287 optical effect Effects 0.000 claims description 16
- 238000003018 immunoassay Methods 0.000 claims description 15
- 238000011068 loading method Methods 0.000 claims description 10
- 238000005406 washing Methods 0.000 claims description 9
- 230000006835 compression Effects 0.000 claims description 7
- 238000007906 compression Methods 0.000 claims description 7
- 239000011324 bead Substances 0.000 claims description 5
- 230000000903 blocking effect Effects 0.000 claims description 4
- 230000001360 synchronised effect Effects 0.000 claims description 4
- 238000004445 quantitative analysis Methods 0.000 claims description 2
- 238000000926 separation method Methods 0.000 claims 2
- 230000006872 improvement Effects 0.000 description 9
- 238000001514 detection method Methods 0.000 description 8
- 230000008878 coupling Effects 0.000 description 6
- 238000010168 coupling process Methods 0.000 description 6
- 238000005859 coupling reaction Methods 0.000 description 6
- 238000005516 engineering process Methods 0.000 description 5
- 238000003745 diagnosis Methods 0.000 description 3
- 230000007547 defect Effects 0.000 description 2
- 238000011049 filling Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 208000023275 Autoimmune disease Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000003771 laboratory diagnosis Methods 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 125000006850 spacer group Chemical group 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5302—Apparatus specially adapted for immunological test procedures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1048—General features of the devices using the transfer device for another function
- G01N2035/1058—General features of the devices using the transfer device for another function for mixing
Abstract
The invention provides a mixing and sample adding assembly of an incubation module of an immunity quantitative analyzer, which belongs to the technical field of immunity quantitative analyzers, and comprises an incubation plate mounting plate arranged on a bottom plate, wherein an incubation plate main shaft is arranged on the incubation plate mounting plate, an incubation plate assembly is sleeved on the incubation plate main shaft, an incubation plate driving device is also arranged on the incubation plate mounting plate, the mixing and sample adding device is arranged on one side of the incubation plate assembly, the mixing and sample adding device comprises a lifting mechanism arranged on the bottom plate, a rotating mechanism arranged at the top end of the lifting mechanism, and a liquid absorbing mechanism is arranged on the rotating mechanism; the invention realizes the automatic operation of the whole incubation module and improves the working efficiency; the arrangement of the incubation plate component solves the technical problem that the plate card is stable in the incubation plate; the technical problem of automatic even mixing and sample adding to the plate card in the incubation plate is realized.
Description
Technical Field
The invention relates to an incubation module of an immunity quantitative analyzer;
in particular to a mixing and sample adding component of an incubation module of an immunity quantitative analyzer.
Background
The fluorescence immunoassay technology utilizes the combination of the high sensitivity of the fluorescence technology and the high specificity of the immunological technology, and provides a detection technology which cannot be replaced by other methods and has a unique style for immunology, clinical histochemistry and laboratory diagnosis.
The fluorescent immunoassay quantitative analyzer serving as an application carrier of the fluorescent immunoassay technology is widely used for detection of serum antibodies (including autoantibodies), diagnosis and research of autoimmune diseases, diagnosis and research of tumor immunity and the like besides identification of bacteria, viruses, protozoa, worms, fungi and the like and diagnosis of related diseases.
With the increase of examination items, the detection of modern fluorescent immunoassay analyzers has increased from tens of detection per hour to hundreds to thousands of detection items.
With the widespread use of fluorescent immunoassays, the number of examination items has increased greatly. The existing single-channel fluorometer and multi-channel fluorometer in the market have the defects of low automation degree, old structure, imperfect flow layout and the like, and can not meet the market demands. The current market is demanding more efficient new models to meet this new demand.
The existing fluorescence immunoassay in the market has the following problems in the incubation module:
first: the incubation plate structure is too simple to solve the technical problem that the plate card is stable in the incubation plate;
second,: the technical problem that the automatic even mixing and sample adding to the board card in the incubation tray cannot be realized;
therefore, the automatic operation of the whole incubation module cannot be realized, the whole incubation module needs to be completed with manual assistance, and the working efficiency is reduced.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides a mixing and sample adding assembly of an incubation module of an immunity quantitative analyzer.
The aim of the invention is achieved by the following technical measures: the utility model provides a module was hatched to immunity quantitative analysis appearance's mixing application of sample subassembly, including installing the incubation dish mounting panel on the bottom plate, be equipped with on the incubation dish mounting panel and incubate a main shaft, incubation dish main shaft is last to be overlapped and is equipped with incubation dish subassembly, still be equipped with on the incubation dish mounting panel and incubate a drive arrangement, set up the mixing application of sample device of incubation dish subassembly one side, its characterized in that: the mixing and sample adding device comprises a lifting mechanism arranged on a bottom plate, a rotating mechanism arranged at the top end of the lifting mechanism, and a liquid absorbing mechanism arranged on the rotating mechanism.
As an improvement, the lifting mechanism comprises a support column arranged on a bottom plate, wherein an assembly seat is arranged on the support column, a slide rail mounting plate is arranged on the assembly seat, a slide rail in the vertical direction is arranged on the slide rail mounting plate, a slide block is arranged on the slide rail, a swing lifting motor seat is arranged on the slide rail mounting plate, a first bearing hole is arranged on one side of the swing lifting motor seat, a screw shaft seat is further arranged on the slide rail mounting plate, a second bearing hole is arranged on the screw shaft seat, and the first bearing hole and the second bearing hole are coaxially arranged; the novel sliding block is characterized in that a screw is arranged between the first bearing hole and the second bearing hole, a swing lifting motor is further arranged on the swing lifting motor seat, the swing lifting motor is in power connection with the screw, a swing bearing seat is arranged on the sliding block, a nut sleeved on the screw is arranged on one side of the swing bearing seat, and a liquid suction mechanism and a rotating mechanism thereof are arranged on the swing bearing seat.
As a further improvement, the lifting mechanism further comprises a lifting distance control device, the lifting distance control device comprises an optical coupler support plate arranged on the sliding rail mounting plate, a first optical coupler is arranged at one end of the optical coupler support plate, a second optical coupler is arranged at the other end of the optical coupler support plate, and an optical coupler baffle is further arranged on the sliding block.
As a further improvement, the rotating mechanism comprises a swing motor arranged on the swing bearing seat, a swing bearing is arranged in the swing bearing seat, the swing bearing shaft is in power connection with the swing motor through a coupler, a swing arm is arranged on a flange of the swing bearing, and a liquid suction mechanism is arranged on the swing arm.
As a further improvement, the liquid suction mechanism comprises a suction needle, a suction needle guide sleeve is sleeved on the periphery of the upper part of the suction needle, and the suction needle guide sleeve is fixedly connected with the swing arm; a needle pressing plate seat is arranged on the swing arm, and a needle pressing plate is arranged on the needle pressing plate seat; the suction needle is sleeved with a compression spring, and the compression spring is positioned between the needle pressing plate and the suction needle guide sleeve.
As a further improvement, the needle pressing plate seat is fixedly connected with the swing arm through a needle pressing plate seat support plate, a guide groove is further formed in the needle pressing plate seat support plate, a needle lifting optocoupler baffle is arranged on the suction needle, the needle lifting optocoupler baffle is arranged in the guide groove, and a needle lifting optocoupler is further arranged on the needle pressing plate seat support plate.
As a further improvement, the needle washing mechanism comprises a needle washing pool mounting plate arranged on the assembly seat, and a needle sucking pool is arranged on the needle washing pool mounting plate.
As a further improvement, the incubation tray assembly comprises a circular incubation tray and an incubation tray driving mechanism, a plurality of plate clamping grooves are formed in the incubation tray, the plate clamping grooves are radially arranged with the circle center of the incubation tray as the center, one side of the plate clamping grooves, which is close to the circle center, is provided with a narrow opening, one side of the plate clamping grooves, which is far away from the circle center, is provided with an opening, a pressing sheet is arranged on the incubation tray between two adjacent plate clamping grooves, the pressing sheet extends to the upper side of the plate clamping grooves, and at least one collision bead is arranged in the plate clamping grooves.
As a further improvement, the incubation disc driving mechanism comprises an incubation disc rotating sleeve sleeved on the incubation disc main shaft, an incubation disc driven wheel is arranged on the incubation disc rotating sleeve, an incubation disc motor is arranged on the incubation disc mounting plate, the incubation disc motor is in power connection with an incubation disc driving wheel, and the incubation disc driving wheel is in power connection with the incubation disc driven wheel through an incubation disc synchronous belt.
As a further improvement, the incubation plate assembly further comprises an incubation plate rotation control mechanism, and the incubation plate rotation control mechanism comprises an incubation plate optocoupler baffle and an incubation plate zero position optocoupler baffle which are arranged on the incubation plate rotating sleeve.
Due to the adoption of the technical scheme, compared with the prior art, the invention has the advantages that:
first: the invention realizes the automatic operation of the whole incubation module and improves the working efficiency;
second,: the arrangement of the incubation plate component solves the technical problem that the plate card is stable in the incubation plate;
third,: the technical problem of automatic even mixing and sample adding to the plate card in the incubation plate is realized.
The invention is further described below with reference to the drawings and the detailed description.
Drawings
FIG. 1 is a schematic illustration of a construction of the present invention;
FIG. 2 is a schematic view of another angular configuration of the present invention;
FIG. 3 is a schematic view of a portion of the components of the present invention;
FIG. 4 is a schematic view of another angular configuration of FIG. 3;
FIG. 5 is a schematic view of another part of the assembly of the present invention;
FIG. 6 is a schematic view of a portion of the structure of an incubation plate assembly of the present invention;
FIG. 7 is a schematic view of the structure of the incubation plate of the present invention;
FIG. 8 is a schematic view of a portion of the components of the present invention;
fig. 9 is a schematic view of a part of the components in the present invention.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings are merely for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the apparatus or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present invention.
In the present invention, unless explicitly specified and limited otherwise, the terms "mounted," "configured," "connected," "secured," "screwed," and the like are to be construed broadly and may be, for example, fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; either directly or indirectly through intermediaries, or in communication with each other or in interaction with each other, unless explicitly defined otherwise, the meaning of the terms described above in this application will be understood by those of ordinary skill in the art in view of the specific circumstances.
Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include one or more such feature. In the description of the present invention, the meaning of "a plurality" is two or more, unless explicitly defined otherwise.
Examples: as shown in fig. 1-9, a mixing and sample adding assembly of an incubation module of an immune quantitative analyzer comprises an incubation plate mounting plate 200 mounted on a bottom plate 100, wherein an incubation plate main shaft 300 is arranged on the incubation plate mounting plate 200, an incubation plate assembly 400 is sleeved on the incubation plate main shaft 300, an incubation plate driving device 500 is further arranged on the incubation plate mounting plate 200, and a mixing and sample adding device 600 arranged on one side of the incubation plate assembly 400.
As shown in fig. 3 to 5, the mixing and loading device 600 includes a lifting mechanism mounted on the base plate 100, a rotating mechanism disposed at the top end of the lifting mechanism, and a liquid absorbing mechanism disposed on the rotating mechanism. The liquid suction mechanism is a functional component for sucking liquid and transferring the liquid, the uniform mixing and sample adding component realizes the position transfer of the suction needle through the lifting mechanism and the rotating mechanism, and the liquid suction function is finished in an auxiliary way by a pump valve component of the instrument.
The lifting mechanism comprises a support post 611 arranged on the bottom plate 100, a component seat 612 is arranged on the support post 611, a slide rail mounting plate 613 is arranged on the component seat 612, a slide rail 614 in the vertical direction is arranged on the slide rail mounting plate 613, a sliding block 615 which moves in a reciprocating manner is arranged on the slide rail 614, a swinging lifting motor seat 616 is arranged on the upper end surface of the slide rail mounting plate 613, a first bearing hole (not shown in the figure) is arranged on one side of the slide rail 614, a screw shaft seat 617 is further arranged below the slide rail mounting plate 613, a second bearing hole 618 is arranged on the screw shaft seat 617, and the first bearing hole and the second bearing hole 618 are coaxially arranged; the first bearing hole and the second bearing hole 618 are internally provided with bearings, the bearings are used as mounting supports, a screw rod 619 is arranged in each bearing hole, a swing lifting motor 620 is further arranged on each swing lifting motor base 616, the swing lifting motor 620 is in power connection with the screw rod 619, a swing bearing seat 621 is arranged on each sliding block 615, a nut 622 sleeved on the screw rod 619 is arranged on one side of each swing bearing seat 621, and when the screw rod 619 rotates, the nut 622 is driven and drives the swing bearing seat 621 to move along the direction of the sliding rail 614; the swing bearing block 621 is provided with a liquid suction mechanism and a rotation mechanism thereof. The power source for rotation of the screw 619 is a swing lift motor 620 mounted to the swing lift motor mount 616.
The lifting mechanism further comprises a lifting distance control device, the lifting distance control device comprises an optocoupler support plate 623 arranged on the sliding rail mounting plate 613, a first optocoupler 624 is arranged at one end of the optocoupler support plate 623, a second optocoupler 625 is arranged at the other end of the optocoupler support plate 623, an optocoupler baffle 626 is further arranged on the sliding block 615, and the lifting distance of the liquid suction mechanism 630 is precisely controlled by a control system of the first optocoupler 624, the second optocoupler 625, the optocoupler baffle 626 and the swinging lifting motor 620.
The rotating mechanism comprises a swing motor 641 arranged on a swing bearing seat 621, a swing bearing (not shown in the figure) is arranged in the swing bearing seat 621, the swing bearing is fixed on the swing bearing seat 621 through a swing bearing inner ring pressing plate (not shown in the figure) and a swing bearing outer ring pressing plate (not shown in the figure), the swing bearing shaft is in power connection with the swing motor 641 through a coupler 642, a swing arm 643 is arranged on a flange of the swing bearing, and a liquid suction mechanism is arranged on the swing arm 643; a swing motor coupling plate 644 is fixed to one side of the swing bearing block 621, and the swing motor 641 is mounted on the swing motor block 645 and is fixed to the swing motor coupling plate 644 through the swing motor block 645; the positioning accuracy of the swing is realized by the cooperation of the swing optocoupler 646, the swing optocoupler baffle 647 and the control system to control the movement of the swing motor 641.
The liquid sucking mechanism comprises a sucking needle 661, and the liquid sucking function of the sucking needle 661 is finished by the sucking needle system in an auxiliary way through a pump valve part of the instrument; a suction needle guide sleeve 662 is sleeved on the periphery of the upper part of the suction needle 661, and the suction needle guide sleeve 662 is fixedly connected with the swing arm 643; the middle hole of the suction needle guide sleeve 662 is a step hole, a suction needle flange (not shown in the figure) is arranged at the middle upper part of the suction needle 661, a needle lifting optocoupler baffle 664 is arranged on the edge of the suction needle flange, and the lower part of the suction needle flange passes through the step hole (not shown in the figure) in the middle of the suction needle guide sleeve 662 and is in clearance fit with the small hole of the step hole; a needle pressing plate seat 665 is arranged on the swing arm 643, and a needle pressing plate 666 is arranged on the needle pressing plate seat 665; the suction needle 661 is sleeved with a compression spring 667, the compression spring 667 is positioned between the needle pressure plate 666 and the flange of the suction needle guide sleeve 662, and downward pressure is applied to the suction needle 661 through the compression spring 667.
The needle pressing plate seat 665 is fixedly connected with the swing arm 643 through a needle pressing plate seat support plate 668, a guide groove 669 is further formed in the needle pressing plate seat support plate 668, a needle lifting optocoupler baffle 664 is arranged in the guide groove 669, and a needle lifting optocoupler 663 is further arranged on the needle pressing plate seat support plate 668; the needle lifting optocoupler baffle 664 is matched with the needle lifting optocoupler 663 arranged on the needle pressing plate seat support plate 668 to sense the contact between the suction needle 661 and the bottom of the container; and the pin lifting optocoupler baffle 664 and the guide groove 669 can also prevent the rotation of the suction pin 661 along the axis. The suction needle 661 is raised or lowered by moving the swing bearing block 621 up and down.
The needle washing mechanism further comprises a needle washing pool mounting plate 681 mounted on the assembly base 612, and a needle sucking pool 682 is arranged on the needle washing pool mounting plate 681.
As shown in fig. 6 to 9, the incubation plate assembly 400 is installed at the upper part of the incubation plate mounting plate 200; the incubation tray assembly 400 includes a circular incubation tray 410 and an incubation tray driving device 500, the incubation tray 410 is made of plastic or metal material and is a carrying body of the board 700, 16 board card slots 411 are formed in the incubation tray 410, the board card slots 411 carry the board card 700 from the card bin assembly, the board card slots 411 are radially arranged with a center of the incubation tray 410 as a center, a narrow opening 412 is formed in one side of the board card slots 411 near the center, the narrow opening 412 forms a step for blocking the board card 700, an opening 413 is formed in one side of the board card slots 411 away from the center, the opening 413 is an opening which gradually increases from inside to outside, such arrangement can enable the board card 700 to easily enter the board card slots 411, pressing pieces 414 are formed on the incubation tray 410 between two adjacent board card slots 411, the pressing pieces 414 extend to the upper side of the board card slots 411, and the two pressing pieces 414 above form a semi-closed space; the two collision beads 415 are disposed in the card slot 411, the two collision beads 415 act on the bottom surface of the card 700 to make the upper surface of the card 700 contact with the lower surfaces of the two pressing pieces 414, and by adjusting the pressure of the two collision beads 415, the card 700 can freely enter and exit in the card slot 411 and can not move by itself when the incubation plate assembly 400 rotates.
The incubation disc driving device 500 comprises an incubation disc rotating sleeve 510 sleeved on the incubation disc main shaft 300, the incubation disc main shaft 300 passes through a round hole on the incubation disc mounting plate 200 and is fixed on the incubation disc mounting plate 200 through a flange, a step 310 is arranged on the incubation disc main shaft 300 at the part above the incubation disc mounting plate 200, two bearings 515 are arranged on the upper part of the step 310, the bearings 515 are fixed on the step 310 through a spacer 516 and an incubation disc rotating sleeve bearing cover 517, and the outer ring of each bearing 515 is provided with the incubation disc rotating sleeve 510.
The incubation plate rotating sleeve 510 is provided with an incubation plate driven wheel 511, the incubation plate mounting plate 200 is provided with an incubation plate motor 512, the incubation plate motor 512 is in power connection with an incubation plate driving wheel 513, and the incubation plate driving wheel 513 is in power connection with the incubation plate driven wheel 511 through an incubation plate synchronous belt 514.
The incubation disc assembly 400 further comprises an incubation disc rotation control mechanism, the incubation disc rotation control mechanism comprises an incubation disc optical coupling baffle 421 and an incubation disc zero optical coupling baffle 422 which are arranged on the incubation disc rotating sleeve 510, specifically speaking, the incubation disc optical coupling baffle 421 is arranged on the lower end face of the incubation disc rotating sleeve 510, the incubation disc driven wheel 511 is arranged below the incubation disc optical coupling baffle 421, and the incubation disc 410 is fixed on the upper end face of the incubation disc rotating sleeve 510.
The incubation plate motor 512 is mounted on the incubation plate mounting plate 200 through an incubation plate motor mounting plate, and the incubation plate driving wheel 513 drives the incubation plate driven wheel 511 through the incubation plate synchronous belt 514, so that the combination formed by the incubation plate driven wheel 511, the incubation plate optocoupler baffle 421, the incubation plate rotating sleeve 510 and the incubation plate 410 rotates around the incubation plate spindle 300. The 16-channel board slots 411 on the incubation tray assembly 400 need to be positioned precisely, and the positioning precision is controlled by the incubation tray zero position optocoupler blocking pieces 422 and the incubation tray optocoupler blocking pieces 421 in cooperation with the incubation tray optocouplers 423 through a control system.
The 16 boards 700 in the board slot 411 on the incubation tray 410 need to complete preparation tasks such as filling liquid and incubation before detection. After entering the card slot 411, the card 700 needs to be turned to the dripping position, and the liquid is filled into the mixing and sample adding device 600. After filling with liquid, incubation for a certain period of time is also required. The boards 700 in the 16-channel board card slots 411 on the incubation tray 410 are sequentially injected and incubated according to program control, and then sequentially sent to a detection position for detection.
The foregoing description of the preferred embodiments of the invention is not intended to be limiting, but rather is intended to cover all modifications, equivalents, and alternatives falling within the spirit and principles of the invention.
Claims (10)
1. The utility model provides a module was hatched to immunity quantitative analysis appearance's mixing application of sample subassembly, including installing the incubation dish mounting panel on the bottom plate, be equipped with on the incubation dish mounting panel and incubate a main shaft, incubation dish main shaft is last to be overlapped and is equipped with incubation dish subassembly, still be equipped with on the incubation dish mounting panel and incubate a drive arrangement, set up the mixing application of sample device of incubation dish subassembly one side, its characterized in that: the mixing and sample adding device comprises a lifting mechanism arranged on a bottom plate, a rotating mechanism arranged at the top end of the lifting mechanism, and a liquid absorbing mechanism arranged on the rotating mechanism.
2. The mixing and loading assembly of an incubation module of an immunoassay quantitative analyzer of claim 1, wherein: the lifting mechanism comprises a support column arranged on a bottom plate, a component seat is arranged on the support column, a slide rail mounting plate is mounted on the component seat, a slide rail in the vertical direction is mounted on the slide rail mounting plate, a slide block is arranged on the slide rail mounting plate, a swing lifting motor seat is mounted on the slide rail mounting plate, a first bearing hole is formed in one side of the swing lifting motor seat, a screw shaft seat is further arranged on the slide rail mounting plate, a second bearing hole is formed in the screw shaft seat, and the first bearing hole and the second bearing hole are coaxially arranged; the novel sliding block is characterized in that a screw is arranged between the first bearing hole and the second bearing hole, a swing lifting motor is further arranged on the swing lifting motor seat, the swing lifting motor is in power connection with the screw, a swing bearing seat is arranged on the sliding block, a nut sleeved on the screw is arranged on one side of the swing bearing seat, and a liquid suction mechanism and a rotating mechanism thereof are arranged on the swing bearing seat.
3. The mixing and loading assembly of an incubation module of an immunoassay quantitative analyzer of claim 2, wherein: the lifting mechanism further comprises a lifting distance control device, the lifting distance control device comprises an optical coupler support plate arranged on the sliding rail mounting plate, a first optical coupler is arranged at one end of the optical coupler support plate, a second optical coupler is arranged at the other end of the optical coupler support plate, and an optical coupler blocking piece is further arranged on the sliding block.
4. A mixing and loading assembly for an incubation module of an immunoassay quantitative analyzer according to claim 3, wherein: the rotating mechanism comprises a swing motor arranged on the swing bearing seat, a swing bearing is arranged in the swing bearing seat, the swing bearing shaft is in power connection with the swing motor through a coupler, a swing arm is arranged on a flange of the swing bearing, and a liquid suction mechanism is arranged on the swing arm.
5. The mixing and loading assembly of an incubation module of an immunoassay quantitative analyzer of claim 4, wherein: the liquid suction mechanism comprises a suction needle, a suction needle guide sleeve is sleeved on the periphery of the upper part of the suction needle, and the suction needle guide sleeve is fixedly connected with the swing arm; a needle pressing plate seat is arranged on the swing arm, and a needle pressing plate is arranged on the needle pressing plate seat; the suction needle is sleeved with a compression spring, and the compression spring is positioned between the needle pressing plate and the suction needle guide sleeve.
6. The mixing and loading assembly of an incubation module of an immunoassay quantitative analyzer of claim 5, wherein: needle pressure board seat pass through needle pressure board seat extension board with swing arm fixed connection, still be equipped with the guide way on the needle pressure board seat extension board, be equipped with needle lift opto-coupler separation blade on the suction needle, needle lift opto-coupler separation blade place in the guide way, still be equipped with needle lift opto-coupler on the needle pressure board seat extension board.
7. The mixing and loading assembly of an incubation module of an immunoassay quantitative analyzer of claim 2, wherein: the needle washing mechanism further comprises a needle washing pool mounting plate arranged on the assembly seat, and a needle sucking pool is arranged on the needle washing pool mounting plate.
8. The mixing and loading assembly of an incubation module of an immunoassay quantitative analyzer of claim 1, wherein: the incubation tray assembly comprises a circular incubation tray and an incubation tray driving device, a plurality of plate clamping grooves are formed in the incubation tray, the plate clamping grooves are arranged radially with the center of the incubation tray as the center, a narrow opening is formed in one side, close to the center, of the plate clamping grooves, an opening is formed in one side, far away from the center, of the plate clamping grooves, a pressing sheet is arranged on the incubation tray between two adjacent plate clamping grooves, the pressing sheet extends to the upper portion of the plate clamping grooves, and at least one collision bead is arranged in the plate clamping grooves.
9. The mixing and loading assembly of an incubation module of an immunoassay quantitative analyzer of claim 8, wherein: the incubation disc driving device comprises an incubation disc rotating sleeve sleeved on the incubation disc main shaft, an incubation disc driven wheel is arranged on the incubation disc rotating sleeve, an incubation disc motor is arranged on the incubation disc mounting plate, the incubation disc motor is in power connection with an incubation disc driving wheel, and the incubation disc driving wheel is in power connection with the incubation disc driven wheel through an incubation disc synchronous belt.
10. The mixing and loading assembly of an incubation module of an immunoassay quantitative analyzer of claim 9, wherein: the incubation plate assembly further comprises an incubation plate rotation control mechanism, and the incubation plate rotation control mechanism comprises an incubation plate optocoupler baffle and an incubation plate zero position optocoupler baffle which are arranged on the incubation plate rotating sleeve.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310783897.9A CN116500253B (en) | 2023-06-29 | 2023-06-29 | Mixing and sample adding assembly of incubation module of immunity quantitative analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310783897.9A CN116500253B (en) | 2023-06-29 | 2023-06-29 | Mixing and sample adding assembly of incubation module of immunity quantitative analyzer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN116500253A true CN116500253A (en) | 2023-07-28 |
| CN116500253B CN116500253B (en) | 2023-10-20 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202310783897.9A Active CN116500253B (en) | 2023-06-29 | 2023-06-29 | Mixing and sample adding assembly of incubation module of immunity quantitative analyzer |
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| CN (1) | CN116500253B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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