CN116499974A - Chemical analysis device, analysis method and clinical examination box - Google Patents
Chemical analysis device, analysis method and clinical examination box Download PDFInfo
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- CN116499974A CN116499974A CN202310764774.0A CN202310764774A CN116499974A CN 116499974 A CN116499974 A CN 116499974A CN 202310764774 A CN202310764774 A CN 202310764774A CN 116499974 A CN116499974 A CN 116499974A
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- 238000004458 analytical method Methods 0.000 title claims abstract description 80
- 239000000126 substance Substances 0.000 title claims abstract description 52
- 238000005070 sampling Methods 0.000 claims abstract description 81
- 238000012360 testing method Methods 0.000 claims abstract description 32
- 238000001514 detection method Methods 0.000 claims description 14
- 239000012491 analyte Substances 0.000 claims description 9
- 230000005540 biological transmission Effects 0.000 claims description 9
- 238000005286 illumination Methods 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 7
- 238000002347 injection Methods 0.000 claims description 5
- 239000007924 injection Substances 0.000 claims description 5
- 238000009614 chemical analysis method Methods 0.000 claims description 3
- 238000010183 spectrum analysis Methods 0.000 abstract description 6
- 239000003795 chemical substances by application Substances 0.000 description 9
- 239000003153 chemical reaction reagent Substances 0.000 description 5
- 238000002834 transmittance Methods 0.000 description 5
- 238000013480 data collection Methods 0.000 description 4
- 238000011161 development Methods 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 230000007306 turnover Effects 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 3
- 238000010876 biochemical test Methods 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 238000004590 computer program Methods 0.000 description 2
- 210000002700 urine Anatomy 0.000 description 2
- 238000012935 Averaging Methods 0.000 description 1
- 238000004566 IR spectroscopy Methods 0.000 description 1
- 238000005481 NMR spectroscopy Methods 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 238000001479 atomic absorption spectroscopy Methods 0.000 description 1
- 238000001636 atomic emission spectroscopy Methods 0.000 description 1
- 238000009534 blood test Methods 0.000 description 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 238000007705 chemical test Methods 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 238000007405 data analysis Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000001917 fluorescence detection Methods 0.000 description 1
- 238000004817 gas chromatography Methods 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 238000010166 immunofluorescence Methods 0.000 description 1
- 230000010365 information processing Effects 0.000 description 1
- 230000001678 irradiating effect Effects 0.000 description 1
- 230000031700 light absorption Effects 0.000 description 1
- 238000004949 mass spectrometry Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000001579 optical reflectometry Methods 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 238000000870 ultraviolet spectroscopy Methods 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
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- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
The invention provides a chemical analysis device, an analysis method and a clinical test box, which aim to improve the accuracy of AD values, and the chemical analysis device is characterized in that a second driving piece and a third driving piece are sequentially awakened to drive a photosensitive sampling piece to move along a tested paper area and collect a plurality of groups of AD values, the collected groups of AD values are sequentially recorded to obtain the average value of the plurality of groups of AD values, the average value is used for analyzing the content of a tested object on the current tested paper, the accuracy of the tested value is improved, the problems that the spectrum analysis in the current chemical analysis device is realized, the tested object is usually fixedly collected, but the data deviation condition of the tested data occurs according to the different current collection positions due to the uneven distribution condition of the tested object on the test paper are easily caused, and the analysis result is affected by the inaccuracy of the tested data are solved.
Description
Technical Field
The invention relates to the technical field of chemical analysis, in particular to a chemical analysis device, an analysis method and a clinical test box.
Background
Analysis based on chemical reactions using substances is called chemical analysis. The long history of chemical analysis is the basis of analytical chemistry, also known as classical analysis. Chemical analysis is absolute quantification, and the amount of the component to be measured is calculated from the amount of the sample, the amount of the reaction product or the amount of the consumed reagent and the stoichiometric relationship of the reaction. Yet another important analytical method, instrumental analysis (instrument analysis), is relative quantitative, estimated from a standard operating curve.
The chemical analysis device is also called a chemical analysis instrument, wherein the instrument analysis refers to a method for acquiring information of chemical composition, component content, chemical structure and the like of a substance by measuring parameters and changes of certain physical or physical chemical properties of the substance by using relatively complex or special instruments and equipment, such as nuclear magnetic resonance spectroscopy, atomic emission spectroscopy, gas chromatography, atomic absorption spectroscopy, high performance liquid chromatography, ultraviolet-visible spectroscopy, mass spectrometry, infrared spectroscopy, other instrument analysis and the like, and the spectrum analysis refers to a method for detecting absorbance of a test strip by irradiating a color development area of the test strip with an LED lamp source with a specific wavelength, capturing reflected signal intensity by using a photosensitive diode and detecting the content of an analyte according to the obtained AD value.
At present, the spectrum analysis in the chemical analysis device is usually fixed to collect the measured object, but due to the uneven distribution of the measured object on the test strip, the measured data is easy to generate data deviation according to different current collection positions, and the analysis result is affected by the inaccuracy of the measured data.
Disclosure of Invention
Based on this, the present invention is to provide a chemical analysis device, an analysis method and a clinical test box, which are used for solving the problems that in the prior art, the spectrum analysis in the chemical analysis device usually collects the measured object in a fixed manner, but the measured data is inaccurate due to the uneven distribution of the measured object on the test strip.
According to the embodiment of the invention, the chemical analysis device comprises an analysis device main body and a sample injection part embedded at one side of the analysis device main body;
the analysis device comprises an analysis device main body, a detection device and a control device, wherein the analysis device main body comprises a sampling table, an LED lamp source arranged above the sampling table, a guide part arranged around the inner bottom of the analysis device main body and a sampling device which is partially embedded in the guide part and moves towards the direction close to and far away from the sampling table, a rectangular through hole for accommodating part of the sampling part is formed in the middle of the sampling table, and the sampling part comprises a bearing plate embedded in the rectangular through hole;
the sampling device comprises a first driving piece connected with the guide part, a fixed plate fixedly connected with the first driving piece, and a movable sampling assembly movably arranged in the fixed plate, wherein a containing groove for containing the movable sampling assembly is formed in the middle of the fixed plate, at least one second guide groove which is oppositely arranged is further embedded in the containing groove, the movable sampling assembly comprises a second driving piece which is oppositely arranged, a guide slide rod which is fixedly arranged on the second driving piece and a third driving piece which is movably arranged on the guide slide rod, the second driving piece is fixedly arranged in the second guide groove, and the third driving piece is arranged at the top of the third driving piece and is oppositely arranged on the bearing plate.
Further, the first driving piece comprises a first motor, a first driving gear arranged at the output end of the first motor, a first driven gear connected with the first driving gear, a linkage rod and a second driven gear which are sequentially arranged along the first driven gear towards the direction of the guide part, and the second driven gear is embedded in the guide part.
Further, a first guide groove for accommodating the second driven gear is formed in the guide part, and a rack matched with the first guide groove extends from the first guide groove towards the direction of the second driven gear.
Further, the sample introduction part further comprises a fourth motor arranged at the top of one side of the sampling table, a fourth driving gear arranged at the output end of the fourth motor, a transmission gear arranged at the bottom of the fourth driving gear and connected with the inner wall of one side of the sample introduction part in an embedded manner with the main body of the analysis device, an output gear connected with the transmission gear, a rotating shaft extending outwards from one side of the output gear close to the sampling table, and a cover plate movably connected with one side of the output gear, wherein the cover plate is far away from the rotating shaft, and the bearing plate is embedded into one side of the rotating shaft far away from the output gear.
Further, the second driving piece comprises a shell fixedly connected with the guide slide rod, a storage battery respectively arranged in the shell, a second motor connected with the storage battery, and a second driving gear arranged on one side output end of the second motor far away from the guide slide rod.
Further, two conductive spring plates propped against the second guide groove are outwards extended from one side of the storage battery, which is far away from the guide sliding rod, and a power-on strip is embedded at the contact part of the second guide groove and the conductive spring plates.
Further, the third driving piece includes the third motor that inside bottom set up, with third motor output shaft's conveyer belt and with the drive wheel that the conveyer belt is connected, run through on the third driving piece and be used for the holding the slide bar spread groove of direction slide bar, the drive wheel is worn out the slide bar spread groove with the direction slide bar supports and leans on, photosensitive sampling piece include with the collection mainboard that third driving piece top is connected and with the photosensitive plate that the collection mainboard is connected.
In addition, the invention also provides a clinical examination box which comprises a chemical analysis device.
A chemical analysis method according to an embodiment of the present invention is used in the chemical analysis apparatus of the present invention, and includes:
acquiring the type of the tested paper, determining the corresponding illumination time length according to the type of the tested paper, and conveying the tested paper to a preset detection area;
after the tested paper reaches the preset detection area, starting an LED lamp source to irradiate the tested paper according to the illumination time length;
scanning the illuminated tested paper through a sampling device, obtaining the reflected signal of the illuminated tested paper, determining an AD value according to the reflected signal, and determining the content of the analyte on the tested paper through the AD value.
Further, the step of scanning the illuminated tested paper by the sampling device to obtain the reflected signal of the illuminated tested paper, determining an AD value according to the reflected signal, and determining the content of the analyte on the tested paper by the AD value includes:
and moving towards the direction approaching to and away from the tested paper through the sampling device, sequentially acquiring the reflected signals of the tested paper at three preset distances through the sampling device to determine three groups of AD values, and averaging the three groups of AD values to determine the actual AD value.
Compared with the prior art: the invention provides a chemical analysis device, an analysis method and a clinical test box, wherein an analyst can wake up first driving parts at two sides of a sampling device through a touch screen, so that the sampling device can be adjusted to determine the using position of the sampling device on a guide part according to the transmittance of the current tested paper, then wake up second driving parts and third driving parts on a movable sampling assembly respectively, the second driving parts drive a guide sliding rod and the third driving parts to transversely slide in a second guide groove, so that a photosensitive sampling part on the third driving parts can be positioned under the tested paper on a bearing plate, finally, the third driving parts are driven to slide along the track of the guide sliding rod, the photosensitive sampling parts are driven to collect multiple data under the tested paper, then, a plurality of AD values of the tested values, namely reflected light signals, are averaged to determine the final content of the tested object, so that the accuracy of the tested values is improved, and the problem that the spectrum analysis in the current chemical analysis device, which is usually a fixed type, collects the tested object is easy to cause that the tested object is unevenly distributed on the tested object, and the tested object is easy to influence the data is accurately collected according to the current position.
Drawings
FIG. 1 is a schematic structural view of a chemical analysis apparatus according to a first embodiment of the present invention;
FIG. 2 is a schematic view showing the internal structure of a chemical analysis apparatus according to a first embodiment of the present invention;
FIG. 3 is a schematic view showing a part of the structure of a guide and a sampling device in a chemical analysis apparatus according to a first embodiment of the present invention;
FIG. 4 is a schematic view showing a part of the structure of a first driving member in the chemical analysis apparatus according to the first embodiment of the present invention;
FIG. 5 is a schematic view showing a partial cross-sectional structure of a movable sampling assembly in a chemical analysis apparatus according to a first embodiment of the present invention;
FIG. 6 is a schematic cross-sectional view of a portion of a second driving member of the chemical analyzer according to the first embodiment of the present invention;
FIG. 7 is a schematic view showing a portion of a sample injection portion of the chemical analyzer according to the first embodiment of the present invention;
fig. 8 is a flow chart of an analysis method of the chemical analysis apparatus according to the second embodiment of the present invention.
Description of main reference numerals:
the following detailed description will further illustrate the invention with reference to the above-described drawings.
Detailed Description
In order that the invention may be readily understood, a more complete description of the invention will be rendered by reference to the appended drawings. Several embodiments of the invention are presented in the figures. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.
It will be understood that when an element is referred to as being "mounted" on another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," and the like are used herein for illustrative purposes only.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The term "and/or" as used herein includes any and all combinations of one or more of the associated listed items.
Example 1
Referring to fig. 1 to 7, which illustrate a chemical analysis apparatus according to a first embodiment of the present invention, in some alternative embodiments of the present invention, the chemical analysis apparatus includes an analysis apparatus main body 1 and a sample introduction portion 2 embedded at one side of the analysis apparatus main body 1, the analysis apparatus main body 1 includes a sample stage 11, an LED light source 13 disposed above the sample stage 11, a guide portion 14 disposed at an inner bottom periphery of the analysis apparatus main body 1, and a sampling device 15 partially embedded in the guide portion 14 and moving toward a direction approaching and separating from the sample stage 11, a rectangular through hole for accommodating the sample introduction portion 2 is formed in a middle portion of the sample stage 11, the sample introduction portion 2 includes a carrier plate 27 embedded in the rectangular through hole, the sampling device 15 includes a first driving member 151 connected with the guide portion 14, a fixed plate 152 fixedly connected with the first driving member 151, and a movable sampling member movably disposed in the fixed plate 152, a receiving groove 153 for accommodating the movable sampling member is formed in the middle portion of the fixed plate 152, at least one second guide groove 154 is also embedded in the receiving groove 153 and at least one second guide groove 154 is disposed in the receiving groove, the movable member includes a second guide member 155 disposed opposite to the second guide member 155, a third driving member 157 disposed opposite to the second driving member 157 disposed opposite to the first driving member and a third driving member 157 disposed opposite to the second driving member 157 disposed opposite to the top member 157.
It should be noted that, the dry chemical test technology includes a dry chemical analyzer and a dry reagent sheet (in this application, the paper to be tested), the dry sheet is a carrier with a fixed reagent, when a sample (serum, plasma, whole blood, urine, cerebrospinal fluid, etc.) is added to the dry sheet, the reagent in the dry sheet and an analyte in the sample generate a color reaction, the reagent and the analyte in the sample are put into the dry chemical analyzer, the incident light emitted by a light source is irradiated onto the dry sheet after color development, and the concentration of the analyte in the sample is calculated according to the corresponding change of the light reflectivity on the dry sheet, in some alternative embodiments of the present invention, a controller may be further provided on the analyzing apparatus main body 1 for controlling the analyzing apparatus main body 1, wherein the controller may be a touch screen, and the touch screen may include an MCU (Microcontroller Unit; micro control unit) chip to control each device in the analyzing apparatus main body 1 through the MCU chip.
Further, the first driving piece 151 comprises a first motor 1511, a first driving gear 1512 arranged at the output end of the first motor 1511, a first driven gear 1513 connected with the first driving gear 1512, a linkage rod 1514 and a second driven gear 1515 which are sequentially arranged along the first driven gear 1513 towards the direction of the guiding part 14, the second driven gear 1515 is embedded in the guiding part 14, a first guiding groove 141 for accommodating the second driven gear 1515 is arranged in the guiding part 14, a rack matched with the rack extends out of the first guiding groove 141 towards the direction of the second driven gear 1515, the sampling part 2 also comprises a fourth motor 21 arranged at the top of one side of the sampling table 11, a fourth driving gear 22 arranged at the output end of the fourth motor 21, a transmission gear 23 arranged at the bottom of the fourth driving gear 22 and connected with the inner wall of one side of the analyzing device main body 1, an output gear 24 connected with the transmission gear 23, a rotating shaft 26 extending outwards from one side of the output gear 24 close to the sampling table 11, and a cover plate 25 movably connected with one side of the output gear 24 away from the rotating shaft 26, the bearing plate 27 is embedded on one side of the rotating shaft 26 far away from the output gear 24, the second driving member 155 comprises a shell 1551 fixedly connected with the guide sliding rod 156, a storage battery 1552 respectively arranged in the shell 1551, a second motor 1553 connected with the storage battery 1552, and a second driving gear 1554 arranged on one side output end of the second motor 1553 far away from the guide sliding rod 156, two conductive elastic sheets 1555 propped against the second guide groove 154 extend outwards from one side of the storage battery 1552 far away from the guide sliding rod 156, a power-on strip is embedded at the contact part of the second guide groove 154 and the conductive elastic sheets 1555, the third driving member 157 comprises a third motor 1574 arranged at the inner bottom, a conveyor belt 1575 connected with the output shaft of the third motor 1574 and a driving wheel 1576 connected with the conveyor belt 1575, the third driving member 157 is penetrated with a slide bar connecting groove 1573 for accommodating the guide slide bar 156, the driving wheel 1576 penetrates out of the slide bar connecting groove 1573 to abut against the guide slide bar 156, and the photosensitive sampling member comprises a collecting main plate 1571 connected with the top of the third driving member 157 and a photosensitive plate 1572 connected with the collecting main plate 1571.
In the embodiment, firstly, an analyst can place the tested paper with the collected tested object in the sample introduction part 2, specifically, the analyst can pull the sample introduction part 2 out of the analysis device main body 1 by pulling the cover plate 25, as shown in the attached drawing 1 of the specification, in some alternative embodiments of the invention, a handle is arranged outside the cover plate 25 towards the analysis device main body 1 so as to facilitate the analyst to pull out the sample introduction part 2, meanwhile, two positioning columns are arranged at the parallel positions of one side of the cover plate 25 towards the bearing plate 27 and two sides of the bearing plate 27, as shown in the attached drawing 7 of the specification, and the positioning columns can be embedded in the sample introduction table 11 after penetrating through the inner wall of the analysis device main body 1, so that the sample introduction part 2 can be pulled out and pushed in the analysis device main body 1 along the track of the positioning columns, and then, after the analyst pulls out the sample introduction part 2, the tested paper can be directly placed on the bearing plate 27, wherein, as required, a light transmission plate is arranged on the bearing plate 27, and in some alternative embodiments can be embedded in the transparent plate 27, and the transparent plate is placed in the test paper, and the middle part can be placed in the test paper, and the test paper is placed in the test paper.
Further, after the analyzer pushes the test paper to the sampling table 11 through the sample feeding portion 2, the analyzer can control to turn on the LED light source 13 through the touch screen, wherein, it is to be noted that the LED light source 13 is specifically disposed right above the rectangular through hole formed in the middle of the sampling table 11, and the bearing plate 27 is distributed in the rectangular through hole after entering the analyzing device main body 1, therefore, the surface of the tested paper is illuminated through the LED light source 13, further, it is to be noted that the LED light source 13 irradiates the color development area of the test paper with the LED light source with a specific wavelength, specifically, the analyzer turns on the fourth motor 21 through the touch screen, so that the fourth motor 21 drives the fourth driving gear 22, the transmission gear 23 and the output gear 24 in turn, then the output gear 24 drives the rotating shaft 26 and the bearing plate 27 disposed on one side thereof to rotate along the center of the output gear 24, in addition, it should be noted that the center of the circle is connected between the output gear 24 and the cover plate 25 through the rotation shaft, when the output gear 24 rotates, the cover plate 25 is limited by the positioning posts at two sides so that the cover plate 25 cannot rotate along with the fluorescent agent when the cover plate 25 rotates, then the output gear 24 drives the bearing plate 27 to turn over for one hundred eighty degrees, the fourth motor 21 stops outputting, so that the tested paper on the bearing plate 27 facing the LED lamp 13 turns over to be opposite to the sampling device 15, and then the sampling device 15 is awakened to scan and analyze the illuminated tested paper, in addition, in some alternative embodiments of the invention, the test means for driving the bearing plate 27 to turn over to be opposite to the sampling device 15 can be applied to the light-proof test paper, the tested object in the test paper can be fused with the fluorescent agent, after the fluorescent agent absorbs light, the tested paper can be relatively convenient to sample with the sampling device 15 through turning over the bearing plate 27, or the bearing plate 27 is not driven to turn over, the test means can be applied to light-transmitting test paper, and the tested object in the test paper can not be fused with fluorescent agent, so that after the test paper is contacted with the tested object, the corresponding color development area on the test paper changes in color, then the LED lamp source 13 irradiates to enable the light source to penetrate through the tested paper and the bearing plate 27 and irradiate to the area of the sampling device 15, and the sampling device 15 collects the reflection data.
Furthermore, the light source reflection signals on the tested paper are collected through the sampling device 15, and as the current transmittance of the tested paper is different, the accuracy of the follow-up tested data can be affected when the tested paper is far away from the sampling device 15 from the bearing plate 27, so that an analyst can wake up the first driving piece 151 on two sides of the sampling device 15 through the touch screen, the use position of the sampling device 15 on the guiding portion can be determined by adjusting the transmittance of the tested paper, the specific use position of the sampling device 15 on the guiding portion 14 can be adjusted, as shown in fig. 3 and 4 of the specification, the analyst can wake up the first motor 1511 in the first driving piece 151 through the touch screen, the first driving gear 1512 at the output end of the analyst can be driven through the first motor 1511, and then the first driven gear 1513, the linkage rod 1514 and the second driven gear 1515 connected at the surrounding edge of the analyst can be sequentially driven to rotate, so that the second driven gear 1515 can move relatively to the rack extending from the inner wall of the first guiding slot 141, the accurate data can be collected along the first guiding slot 141, the accurate data collection range can be guaranteed, and the accurate data collection range can be guaranteed, the data collection device can not be moved along the first guiding slot 141, and the data collection range can be kept close to the adjustable.
Then, after the first driving element 151 drives the fixing plate 152 and other structures to move to a designated height on the guiding portion 14, the movable sampling assembly can be awakened to start information collection on the tested paper on the carrying plate 27, specifically, firstly, it can be understood that as the tested paper has a tested object, part of the light source of the LED light source 13 is absorbed by the test paper when passing through the tested paper, so that the light source signal transmitted into the photosensitive plate 1572 by the tested paper is weaker than the light source signal of the LED light source 13, therefore, after the whole carrying plate 27 is scanned by the photosensitive plate 1572, the position of the tested paper on the carrying plate 27 can be directly determined, in addition, in some alternative embodiments of the invention, when the tested object on the tested paper is doped with fluorescent agent, the LED light source 13 is turned off after the tested paper is fully absorbed, then the sample feeding portion 2 drives the carrying plate 27 to turn over, and then the photosensitive plate 1572 is turned on to scan and locate the light emitting area on the tested paper, which needs to be explained that the photosensitive plate 1572 is always located in the center of the holding groove 153 in the identification process, thus determining the position of the tested paper on the carrying plate 27;
the second driving member 155 and the third driving member 157 on the movable sampling assembly are respectively awakened, the second driving gear 1554 at the output end of the second driving member 155 is rotated by the second motor 1553 in the second driving member 155 and is driven by the racks extending out of the second guide groove 154, so that the guide slide bar 156 connected with the second driving member 155 and the third driving member 157 are driven to slide along the track of the second guide groove 154, the fixing plate 152 can be understood to move transversely, the third driving member 157 moves to the position right below the tested paper on the bearing plate 27 to facilitate the subsequent signal acquisition, the signal acquisition accuracy is improved to a certain extent, meanwhile, as shown in fig. 6 of the specification, a storage battery 1552 can be further arranged in the housing 1551, and meanwhile, a conductive elastic sheet 1555 extends out of the positive electrode and negative electrode of the storage battery 1552 and can be abutted against the electrified strip of the inner wall of the second guide groove 154 for connecting the power supply, the power supply can be provided to the storage battery 1552 or directly provided to the second motor 1553 through the conductive spring plate 1555, which aims to save the trouble of conducting wire arrangement in the second guide groove 154, then the third motor 1574 on the third driving piece 157 is awakened, in addition, a rubber wheel in transmission connection with the conveyor belt 1575 can be arranged at the output end of the third motor 1574, then the conveyor belt 1575 wound around the periphery of the output end of the third motor 1574 is driven by the rubber wheel arranged at the output end of the third motor 1574 to transmit, and meanwhile, the driving wheels 1576 on two sides of the conveyor belt 1575 are driven to rotate in the same direction, wherein the driving wheels 1576 can be made of rubber, so that the situation of slipping at the contact part of the driving wheels 1576 with the guide sliding rod 156 can be ensured, the third driving piece 157 can slip along the track of the guide sliding rod 156, the photosensitive plate 1572 is driven to collect multiple data under the tested paper, and the collecting main plate 1571 collects records uniformly, and then, the measured values, namely a plurality of groups of AD values of the reflected light signals, are averaged to determine the final measured object content so as to improve the accuracy of the measured values.
In summary, an analyst can wake up the first driving member 151 at two sides of the sampling device 15 through the touch screen, so that the adjusting sampling device 15 can determine the use position of the sample device on the guiding portion 14 according to the transmittance of the current tested paper, then wake up the second driving member 155 and the third driving member 157 on the movable sampling assembly respectively, the second driving member 155 drives the guiding sliding rod 156 and the third driving member 157 to slide transversely in the second guiding slot 154, so that the photosensitive sampling member on the third driving member 157 can be located under the tested paper on the bearing plate 27, finally, the third driving member 157 is driven to slide along the track of the guiding sliding rod 156, and the photosensitive sampling member is driven to perform multiple data acquisitions under the tested paper, and then average a plurality of groups of AD values of the measured values, namely reflected light signals, to determine the final content of the measured values, so as to improve the accuracy of the measured values, and solve the problems that the spectrum analysis in the current chemical analysis device is usually the fixed type of collecting the measured paper strips, but the measured materials are unevenly distributed, and the measured materials are liable to influence the data analysis due to the fact that the measured data are unevenly distributed according to the current position.
Example two
Referring to fig. 8, a method for analyzing a chemical analyzer according to a second embodiment of the invention is shown, and the method specifically includes steps S01-S03.
Step S01, obtaining the type of the tested paper, determining the corresponding illumination time length according to the type of the tested paper, and conveying the tested paper to a preset detection area;
in specific implementation, the category of the tested paper is obtained, wherein the category comprises the transmittance of the tested paper, whether the tested object on the tested paper can be fused with the fluorescent agent or not, if the tested object can be fused with the fluorescent agent, the fluorescent detection is marked, the illumination time of the LED lamp source in the analysis device main body for illuminating the tested paper is set according to the optimal light absorption time of the current fluorescent agent, the tested paper is conveyed to the detection area from the sample injection part, and if the tested object can not be fused with the fluorescent agent, the conventional detection is marked, and the tested paper is conveyed to the detection area from the sample injection part.
Step S02, after the tested paper reaches the preset detection area, an LED lamp source is started to irradiate the tested paper according to the illumination time length;
when the test paper enters the detection area and is detected in a conventional way, the loading plate keeps the LED lamp source to be started for irradiation.
And S03, scanning the illuminated tested paper through a sampling device, obtaining the reflected signal of the illuminated tested paper, determining an AD value according to the reflected signal, and determining the content of the analyte on the tested paper through the AD value.
In the specific implementation, when fluorescence detection is carried out, after the loading plate on the sample feeding part is turned over, the LED lamp source is turned off and wakes up the photosensitive sampling piece on the sampling device to scan the illuminated tested paper, and when conventional detection is carried out, the LED lamp source is kept in a normally open state, and meanwhile the photosensitive sampling piece on the sampling device is waken up to scan the tested paper.
Further, the light reflection signals of the tested paper are collected through the photosensitive sampling piece, the AD value is determined according to the reflection signals, in order to improve the accuracy of the AD value, the second driving piece and the third driving piece are sequentially awakened to drive the photosensitive sampling piece to move along the tested paper area and collect multiple groups of AD values, the collected multiple groups of AD values are sequentially recorded to obtain an average value of the multiple groups of AD values, and the average value is used for analyzing the content of the tested object on the tested paper.
In summary, in the analysis method of the chemical analysis device in the above embodiment, in order to improve the accuracy of the AD value, the second driving element and the third driving element are sequentially awakened to drive the photosensitive sampling element to move along the tested paper area and collect multiple groups of AD values, the collected multiple groups of AD values are sequentially recorded to obtain an average value of the multiple groups of AD values, and the average value is used to analyze the content of the tested object on the current tested paper.
Example III
The clinical test kit according to the third embodiment of the present invention includes a chemical analysis device, and in some optional embodiments of the present invention, the clinical test kit further includes a dry blood test module, a dry biochemical test module, an immunofluorescence test module, a coagulation test module, a blood gas test module, a portable urine analyzer, a data information processing module, a power adapter, a mounting assembly, and an accessory, wherein the dry biochemical test module may be the chemical analysis device according to the present invention.
Example IV
Another aspect of the present invention also provides a readable storage medium having stored thereon a computer program, the computer program
The program is executed by a processor to implement the steps of the method according to any one of the first to second embodiments.
In the description of the present specification, a description referring to terms "one embodiment," "some embodiments," "examples," "specific examples," or "some examples," etc., means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present invention. In this specification, schematic representations of the above terms do not necessarily refer to the same embodiments or examples. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The foregoing examples illustrate only a few embodiments of the invention and are described in detail herein without thereby limiting the scope of the invention. It should be noted that it will be apparent to those skilled in the art that several variations and modifications can be made without departing from the spirit of the invention, which are all within the scope of the invention. Accordingly, the scope of protection of the present invention is to be determined by the appended claims.
Claims (10)
1. The chemical analysis device is characterized by comprising an analysis device main body and a sample injection part embedded at one side of the analysis device main body;
the analysis device comprises an analysis device main body, a detection device and a control device, wherein the analysis device main body comprises a sampling table, an LED lamp source arranged above the sampling table, a guide part arranged around the inner bottom of the analysis device main body and a sampling device which is partially embedded in the guide part and moves towards the direction close to and far away from the sampling table, a rectangular through hole for accommodating part of the sampling part is formed in the middle of the sampling table, and the sampling part comprises a bearing plate embedded in the rectangular through hole;
the sampling device comprises a first driving piece connected with the guide part, a fixed plate fixedly connected with the first driving piece, and a movable sampling assembly movably arranged in the fixed plate, wherein a containing groove for containing the movable sampling assembly is formed in the middle of the fixed plate, at least one second guide groove which is oppositely arranged is further embedded in the containing groove, the movable sampling assembly comprises a second driving piece which is oppositely arranged, a guide slide rod which is fixedly arranged on the second driving piece and a third driving piece which is movably arranged on the guide slide rod, the second driving piece is fixedly arranged in the second guide groove, and the third driving piece is arranged at the top of the third driving piece and is oppositely arranged on the bearing plate.
2. The chemical analysis apparatus according to claim 1, wherein the first driving member includes a first motor, a first driving gear provided at an output end of the first motor, a first driven gear coupled to the first driving gear, a link lever and a second driven gear sequentially provided along the first driven gear toward the guide portion, and the second driven gear is fitted to the guide portion.
3. The chemical analysis apparatus according to claim 2, wherein a first guide groove for accommodating the second driven gear is formed in the guide part, and a rack adapted to the first guide groove is extended from the first guide groove toward the second driven gear.
4. The chemical analysis apparatus according to claim 1, wherein the sample introduction portion further comprises a fourth motor disposed at the top of one side of the sampling table, a fourth driving gear disposed at an output end of the fourth motor, a transmission gear disposed at the bottom of the fourth driving gear and connected to an inner wall of one side of the sample introduction portion, an output gear coupled to the transmission gear, a rotating shaft extending outwards from one side of the output gear close to the sampling table, and a cover plate movably connected to one side of the output gear away from the rotating shaft, wherein the bearing plate is embedded on one side of the rotating shaft away from the output gear.
5. The chemical analysis apparatus according to claim 1, wherein the second driving member comprises a housing fixedly connected with the guide slide bar, a storage battery respectively arranged in the housing, a second motor connected with the storage battery, and a second driving gear arranged at an output end of the second motor on a side far away from the guide slide bar.
6. The chemical analysis apparatus according to claim 5, wherein two conductive elastic pieces abutting against the second guide groove are extended outwards from one side of the storage battery away from the guide sliding rod, and a conductive strip is embedded at a contact part of the second guide groove and the conductive elastic pieces.
7. The chemical analysis apparatus according to claim 1, wherein the third driving member includes a third motor disposed at the bottom of the third driving member, a conveyor belt connected to an output shaft of the third motor, and a driving wheel connected to the conveyor belt, a slide bar connecting slot for accommodating the guide slide bar is formed in the third driving member, the driving wheel penetrates through the slide bar connecting slot to abut against the guide slide bar, and the photosensitive sampling member includes a collecting main board connected to the top of the third driving member, and a photosensitive board connected to the collecting main board.
8. A clinical test kit comprising the chemical analysis apparatus of any one of claims 1 to 7.
9. A chemical analysis method for the chemical analysis apparatus according to any one of claims 1 to 7, the method comprising:
acquiring the type of the tested paper, determining the corresponding illumination time length according to the type of the tested paper, and conveying the tested paper to a preset detection area;
after the tested paper reaches the preset detection area, starting an LED lamp source to irradiate the tested paper according to the illumination time length;
scanning the illuminated tested paper through a sampling device, obtaining the reflected signal of the illuminated tested paper, determining an AD value according to the reflected signal, and determining the content of the analyte on the tested paper through the AD value.
10. The chemical analysis method according to claim 9, wherein the step of scanning the illuminated paper to be tested by the sampling device, obtaining a reflected signal of the illuminated paper to be tested, determining an AD value according to the reflected signal, and determining the analyte content on the test paper by the AD value comprises:
and the sampling device moves along the tested paper area, and the sampling device sequentially acquires the reflected signals of the tested paper at three preset distances to determine three groups of AD values, and the AD values of the three groups are averaged to determine the actual AD value.
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