CN116490162A - Two-phase composition - Google Patents
Two-phase composition Download PDFInfo
- Publication number
- CN116490162A CN116490162A CN202180078362.0A CN202180078362A CN116490162A CN 116490162 A CN116490162 A CN 116490162A CN 202180078362 A CN202180078362 A CN 202180078362A CN 116490162 A CN116490162 A CN 116490162A
- Authority
- CN
- China
- Prior art keywords
- composition
- phase
- composition according
- oil
- fatty acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 300
- 239000012071 phase Substances 0.000 claims abstract description 144
- -1 aromatic ketone compound Chemical class 0.000 claims abstract description 119
- 235000014113 dietary fatty acids Nutrition 0.000 claims abstract description 57
- 229930195729 fatty acid Natural products 0.000 claims abstract description 57
- 239000000194 fatty acid Substances 0.000 claims abstract description 57
- 239000008346 aqueous phase Substances 0.000 claims abstract description 45
- 239000002537 cosmetic Substances 0.000 claims abstract description 32
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 25
- 239000003921 oil Substances 0.000 claims description 119
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 32
- 229930195733 hydrocarbon Natural products 0.000 claims description 22
- 238000002156 mixing Methods 0.000 claims description 22
- 239000004215 Carbon black (E152) Substances 0.000 claims description 20
- 150000002430 hydrocarbons Chemical class 0.000 claims description 19
- TXFPEBPIARQUIG-UHFFFAOYSA-N 4'-hydroxyacetophenone Chemical compound CC(=O)C1=CC=C(O)C=C1 TXFPEBPIARQUIG-UHFFFAOYSA-N 0.000 claims description 18
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 16
- 238000000034 method Methods 0.000 claims description 14
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 14
- 102000011782 Keratins Human genes 0.000 claims description 13
- 108010076876 Keratins Proteins 0.000 claims description 13
- 239000000463 material Substances 0.000 claims description 12
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 11
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 11
- 210000000720 eyelash Anatomy 0.000 claims description 9
- 125000003118 aryl group Chemical group 0.000 claims description 7
- 229940073735 4-hydroxy acetophenone Drugs 0.000 claims description 6
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 5
- ZWVHTXAYIKBMEE-UHFFFAOYSA-N 2-hydroxyacetophenone Chemical compound OCC(=O)C1=CC=CC=C1 ZWVHTXAYIKBMEE-UHFFFAOYSA-N 0.000 claims description 4
- 229940043707 polyglyceryl-6 distearate Drugs 0.000 claims description 2
- 229940104257 polyglyceryl-6-dioleate Drugs 0.000 claims description 2
- 239000000839 emulsion Substances 0.000 abstract description 19
- 235000019198 oils Nutrition 0.000 description 108
- 210000003491 skin Anatomy 0.000 description 30
- 229920006395 saturated elastomer Polymers 0.000 description 23
- 229920001296 polysiloxane Polymers 0.000 description 19
- 150000002191 fatty alcohols Chemical class 0.000 description 18
- 230000000052 comparative effect Effects 0.000 description 17
- 150000002148 esters Chemical class 0.000 description 15
- 239000004615 ingredient Substances 0.000 description 13
- 125000000217 alkyl group Chemical group 0.000 description 11
- 125000004432 carbon atom Chemical group C* 0.000 description 11
- 150000004665 fatty acids Chemical class 0.000 description 11
- 229920000742 Cotton Polymers 0.000 description 9
- 239000004480 active ingredient Substances 0.000 description 9
- 125000004122 cyclic group Chemical group 0.000 description 9
- 238000002360 preparation method Methods 0.000 description 9
- 229920002545 silicone oil Polymers 0.000 description 9
- BANXPJUEBPWEOT-UHFFFAOYSA-N 2-methyl-Pentadecane Chemical compound CCCCCCCCCCCCCC(C)C BANXPJUEBPWEOT-UHFFFAOYSA-N 0.000 description 8
- SGVYKUFIHHTIFL-UHFFFAOYSA-N Isobutylhexyl Natural products CCCCCCCC(C)C SGVYKUFIHHTIFL-UHFFFAOYSA-N 0.000 description 8
- 150000001875 compounds Chemical class 0.000 description 8
- 239000007788 liquid Substances 0.000 description 8
- 239000000047 product Substances 0.000 description 8
- 235000000346 sugar Nutrition 0.000 description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 7
- 150000001298 alcohols Chemical class 0.000 description 7
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical class OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 7
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N dodecahydrosqualene Natural products CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 7
- 230000000694 effects Effects 0.000 description 7
- 229920006294 polydialkylsiloxane Polymers 0.000 description 7
- 239000004094 surface-active agent Substances 0.000 description 7
- 230000002051 biphasic effect Effects 0.000 description 6
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 6
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 6
- NKJOXAZJBOMXID-UHFFFAOYSA-N 1,1'-Oxybisoctane Chemical compound CCCCCCCCOCCCCCCCC NKJOXAZJBOMXID-UHFFFAOYSA-N 0.000 description 5
- 206010040844 Skin exfoliation Diseases 0.000 description 5
- 239000003795 chemical substances by application Substances 0.000 description 5
- 239000010696 ester oil Substances 0.000 description 5
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 5
- 238000001556 precipitation Methods 0.000 description 5
- RYYKJJJTJZKILX-UHFFFAOYSA-M sodium octadecanoate Chemical class [Na+].CCCCCCCCCCCCCCCCCC([O-])=O RYYKJJJTJZKILX-UHFFFAOYSA-M 0.000 description 5
- WNWHHMBRJJOGFJ-UHFFFAOYSA-N 16-methylheptadecan-1-ol Chemical compound CC(C)CCCCCCCCCCCCCCCO WNWHHMBRJJOGFJ-UHFFFAOYSA-N 0.000 description 4
- XDOFQFKRPWOURC-UHFFFAOYSA-N 16-methylheptadecanoic acid Chemical compound CC(C)CCCCCCCCCCCCCCC(O)=O XDOFQFKRPWOURC-UHFFFAOYSA-N 0.000 description 4
- 229940043268 2,2,4,4,6,8,8-heptamethylnonane Drugs 0.000 description 4
- GTJOHISYCKPIMT-UHFFFAOYSA-N 2-methylundecane Chemical compound CCCCCCCCCC(C)C GTJOHISYCKPIMT-UHFFFAOYSA-N 0.000 description 4
- LEACJMVNYZDSKR-UHFFFAOYSA-N 2-octyldodecan-1-ol Chemical compound CCCCCCCCCCC(CO)CCCCCCCC LEACJMVNYZDSKR-UHFFFAOYSA-N 0.000 description 4
- UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical compound [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 description 4
- 239000004264 Petrolatum Substances 0.000 description 4
- ZFOZVQLOBQUTQQ-UHFFFAOYSA-N Tributyl citrate Chemical compound CCCCOC(=O)CC(O)(C(=O)OCCCC)CC(=O)OCCCC ZFOZVQLOBQUTQQ-UHFFFAOYSA-N 0.000 description 4
- BTFJIXJJCSYFAL-UHFFFAOYSA-N arachidyl alcohol Natural products CCCCCCCCCCCCCCCCCCCCO BTFJIXJJCSYFAL-UHFFFAOYSA-N 0.000 description 4
- 150000005690 diesters Chemical class 0.000 description 4
- XIRNKXNNONJFQO-UHFFFAOYSA-N ethyl hexadecanoate Chemical compound CCCCCCCCCCCCCCCC(=O)OCC XIRNKXNNONJFQO-UHFFFAOYSA-N 0.000 description 4
- 235000011187 glycerol Nutrition 0.000 description 4
- SFFVATKALSIZGN-UHFFFAOYSA-N hexadecan-7-ol Chemical compound CCCCCCCCCC(O)CCCCCC SFFVATKALSIZGN-UHFFFAOYSA-N 0.000 description 4
- VKPSKYDESGTTFR-UHFFFAOYSA-N isododecane Natural products CC(C)(C)CC(C)CC(C)(C)C VKPSKYDESGTTFR-UHFFFAOYSA-N 0.000 description 4
- KUVMKLCGXIYSNH-UHFFFAOYSA-N isopentadecane Natural products CCCCCCCCCCCCC(C)C KUVMKLCGXIYSNH-UHFFFAOYSA-N 0.000 description 4
- 229940066842 petrolatum Drugs 0.000 description 4
- 235000019271 petrolatum Nutrition 0.000 description 4
- 239000002244 precipitate Substances 0.000 description 4
- 150000008163 sugars Chemical class 0.000 description 4
- WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 description 3
- XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical group [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 3
- 229930006000 Sucrose Natural products 0.000 description 3
- DOOTYTYQINUNNV-UHFFFAOYSA-N Triethyl citrate Chemical group CCOC(=O)CC(O)(C(=O)OCC)CC(=O)OCC DOOTYTYQINUNNV-UHFFFAOYSA-N 0.000 description 3
- 239000007983 Tris buffer Substances 0.000 description 3
- 230000003113 alkalizing effect Effects 0.000 description 3
- GHVNFZFCNZKVNT-UHFFFAOYSA-M decanoate Chemical compound CCCCCCCCCC([O-])=O GHVNFZFCNZKVNT-UHFFFAOYSA-M 0.000 description 3
- SNRUBQQJIBEYMU-UHFFFAOYSA-N dodecane Chemical compound CCCCCCCCCCCC SNRUBQQJIBEYMU-UHFFFAOYSA-N 0.000 description 3
- POULHZVOKOAJMA-UHFFFAOYSA-M dodecanoate Chemical compound CCCCCCCCCCCC([O-])=O POULHZVOKOAJMA-UHFFFAOYSA-M 0.000 description 3
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical class CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 3
- 210000004709 eyebrow Anatomy 0.000 description 3
- 150000002314 glycerols Chemical class 0.000 description 3
- 125000003976 glyceryl group Chemical group [H]C([*])([H])C(O[H])([H])C(O[H])([H])[H] 0.000 description 3
- 229940070765 laurate Drugs 0.000 description 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 3
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 description 3
- HMMGMWAXVFQUOA-UHFFFAOYSA-N octamethylcyclotetrasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 HMMGMWAXVFQUOA-UHFFFAOYSA-N 0.000 description 3
- WWZKQHOCKIZLMA-UHFFFAOYSA-M octanoate Chemical compound CCCCCCCC([O-])=O WWZKQHOCKIZLMA-UHFFFAOYSA-M 0.000 description 3
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 3
- 239000003960 organic solvent Substances 0.000 description 3
- 150000002942 palmitic acid derivatives Chemical class 0.000 description 3
- 229940032094 squalane Drugs 0.000 description 3
- 238000003860 storage Methods 0.000 description 3
- 239000005720 sucrose Substances 0.000 description 3
- TUNFSRHWOTWDNC-UHFFFAOYSA-N tetradecanoic acid Chemical class CCCCCCCCCCCCCC(O)=O TUNFSRHWOTWDNC-UHFFFAOYSA-N 0.000 description 3
- 235000013769 triethyl citrate Nutrition 0.000 description 3
- 235000015112 vegetable and seed oil Nutrition 0.000 description 3
- HJIAMFHSAAEUKR-UHFFFAOYSA-N (2-hydroxyphenyl)-phenylmethanone Chemical compound OC1=CC=CC=C1C(=O)C1=CC=CC=C1 HJIAMFHSAAEUKR-UHFFFAOYSA-N 0.000 description 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 description 2
- IBKQQKPQRYUGBJ-UHFFFAOYSA-N 1-(3,4,5-trihydroxyphenyl)ethanone Chemical compound CC(=O)C1=CC(O)=C(O)C(O)=C1 IBKQQKPQRYUGBJ-UHFFFAOYSA-N 0.000 description 2
- LTSWUFKUZPPYEG-UHFFFAOYSA-N 1-decoxydecane Chemical compound CCCCCCCCCCOCCCCCCCCCC LTSWUFKUZPPYEG-UHFFFAOYSA-N 0.000 description 2
- CMCBDXRRFKYBDG-UHFFFAOYSA-N 1-dodecoxydodecane Chemical compound CCCCCCCCCCCCOCCCCCCCCCCCC CMCBDXRRFKYBDG-UHFFFAOYSA-N 0.000 description 2
- LGEZTMRIZWCDLW-UHFFFAOYSA-N 14-methylpentadecyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCCCCCCCCCCCCC(C)C LGEZTMRIZWCDLW-UHFFFAOYSA-N 0.000 description 2
- OVSKIKFHRZPJSS-UHFFFAOYSA-N 2,4-D Chemical compound OC(=O)COC1=CC=C(Cl)C=C1Cl OVSKIKFHRZPJSS-UHFFFAOYSA-N 0.000 description 2
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 description 2
- OSCJHTSDLYVCQC-UHFFFAOYSA-N 2-ethylhexyl 4-[[4-[4-(tert-butylcarbamoyl)anilino]-6-[4-(2-ethylhexoxycarbonyl)anilino]-1,3,5-triazin-2-yl]amino]benzoate Chemical compound C1=CC(C(=O)OCC(CC)CCCC)=CC=C1NC1=NC(NC=2C=CC(=CC=2)C(=O)NC(C)(C)C)=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=N1 OSCJHTSDLYVCQC-UHFFFAOYSA-N 0.000 description 2
- LEEDMQGKBNGPDN-UHFFFAOYSA-N 2-methylnonadecane Chemical compound CCCCCCCCCCCCCCCCCC(C)C LEEDMQGKBNGPDN-UHFFFAOYSA-N 0.000 description 2
- WRMNZCZEMHIOCP-UHFFFAOYSA-N 2-phenylethanol Chemical compound OCCC1=CC=CC=C1 WRMNZCZEMHIOCP-UHFFFAOYSA-N 0.000 description 2
- UIVPNOBLHXUKDX-UHFFFAOYSA-N 3,5,5-trimethylhexyl 3,5,5-trimethylhexanoate Chemical compound CC(C)(C)CC(C)CCOC(=O)CC(C)CC(C)(C)C UIVPNOBLHXUKDX-UHFFFAOYSA-N 0.000 description 2
- RMTFNDVZYPHUEF-XZBKPIIZSA-N 3-O-methyl-D-glucose Chemical compound O=C[C@H](O)[C@@H](OC)[C@H](O)[C@H](O)CO RMTFNDVZYPHUEF-XZBKPIIZSA-N 0.000 description 2
- LUJMEECXHPYQOF-UHFFFAOYSA-N 3-hydroxyacetophenone Chemical compound CC(=O)C1=CC=CC(O)=C1 LUJMEECXHPYQOF-UHFFFAOYSA-N 0.000 description 2
- HBTAOSGHCXUEKI-UHFFFAOYSA-N 4-chloro-n,n-dimethyl-3-nitrobenzenesulfonamide Chemical compound CN(C)S(=O)(=O)C1=CC=C(Cl)C([N+]([O-])=O)=C1 HBTAOSGHCXUEKI-UHFFFAOYSA-N 0.000 description 2
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 description 2
- KGKQNDQDVZQTAG-UHFFFAOYSA-N 8-methylnonyl 2,2-dimethylpropanoate Chemical compound CC(C)CCCCCCCOC(=O)C(C)(C)C KGKQNDQDVZQTAG-UHFFFAOYSA-N 0.000 description 2
- QZCLKYGREBVARF-UHFFFAOYSA-N Acetyl tributyl citrate Chemical compound CCCCOC(=O)CC(C(=O)OCCCC)(OC(C)=O)CC(=O)OCCCC QZCLKYGREBVARF-UHFFFAOYSA-N 0.000 description 2
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 2
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 description 2
- IUMSDRXLFWAGNT-UHFFFAOYSA-N Dodecamethylcyclohexasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 IUMSDRXLFWAGNT-UHFFFAOYSA-N 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- XNWPXDGRBWJIES-UHFFFAOYSA-N Maclurin Natural products OC1=CC(O)=CC(O)=C1C(=O)C1=CC=C(O)C(O)=C1 XNWPXDGRBWJIES-UHFFFAOYSA-N 0.000 description 2
- FLIACVVOZYBSBS-UHFFFAOYSA-N Methyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC FLIACVVOZYBSBS-UHFFFAOYSA-N 0.000 description 2
- UFWIBTONFRDIAS-UHFFFAOYSA-N Naphthalene Chemical compound C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 description 2
- OQILCOQZDHPEAZ-UHFFFAOYSA-N Palmitinsaeure-octylester Natural products CCCCCCCCCCCCCCCC(=O)OCCCCCCCC OQILCOQZDHPEAZ-UHFFFAOYSA-N 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- NRTJGTSOTDBPDE-UHFFFAOYSA-N [dimethyl(methylsilyloxy)silyl]oxy-dimethyl-trimethylsilyloxysilane Chemical compound C[SiH2]O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C NRTJGTSOTDBPDE-UHFFFAOYSA-N 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 150000001335 aliphatic alkanes Chemical class 0.000 description 2
- 125000001931 aliphatic group Chemical group 0.000 description 2
- 239000010775 animal oil Substances 0.000 description 2
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 description 2
- 125000002511 behenyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 2
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 description 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 2
- ZFMQKOWCDKKBIF-UHFFFAOYSA-N bis(3,5-difluorophenyl)phosphane Chemical compound FC1=CC(F)=CC(PC=2C=C(F)C=C(F)C=2)=C1 ZFMQKOWCDKKBIF-UHFFFAOYSA-N 0.000 description 2
- 150000001860 citric acid derivatives Chemical class 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 229920001577 copolymer Polymers 0.000 description 2
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 description 2
- 229940028820 didecyl ether Drugs 0.000 description 2
- 229940031578 diisopropyl adipate Drugs 0.000 description 2
- 239000004205 dimethyl polysiloxane Substances 0.000 description 2
- PKPOVTYZGGYDIJ-UHFFFAOYSA-N dioctyl carbonate Chemical compound CCCCCCCCOC(=O)OCCCCCCCC PKPOVTYZGGYDIJ-UHFFFAOYSA-N 0.000 description 2
- LQZZUXJYWNFBMV-UHFFFAOYSA-N dodecan-1-ol Chemical compound CCCCCCCCCCCCO LQZZUXJYWNFBMV-UHFFFAOYSA-N 0.000 description 2
- MMXKVMNBHPAILY-UHFFFAOYSA-N ethyl laurate Chemical compound CCCCCCCCCCCC(=O)OCC MMXKVMNBHPAILY-UHFFFAOYSA-N 0.000 description 2
- MMKRHZKQPFCLLS-UHFFFAOYSA-N ethyl myristate Chemical compound CCCCCCCCCCCCCC(=O)OCC MMKRHZKQPFCLLS-UHFFFAOYSA-N 0.000 description 2
- 229940067592 ethyl palmitate Drugs 0.000 description 2
- GJQLBGWSDGMZKM-UHFFFAOYSA-N ethylhexyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(CC)CCCCC GJQLBGWSDGMZKM-UHFFFAOYSA-N 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 239000008103 glucose Substances 0.000 description 2
- 230000005484 gravity Effects 0.000 description 2
- 239000008240 homogeneous mixture Substances 0.000 description 2
- 229920006007 hydrogenated polyisobutylene Polymers 0.000 description 2
- 229940078545 isocetyl stearate Drugs 0.000 description 2
- 229940100554 isononyl isononanoate Drugs 0.000 description 2
- 229940115478 isopropyl lauroyl sarcosinate Drugs 0.000 description 2
- XUGNVMKQXJXZCD-UHFFFAOYSA-N isopropyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(C)C XUGNVMKQXJXZCD-UHFFFAOYSA-N 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 229940057995 liquid paraffin Drugs 0.000 description 2
- 210000004400 mucous membrane Anatomy 0.000 description 2
- 125000001624 naphthyl group Chemical group 0.000 description 2
- CRSOQBOWXPBRES-UHFFFAOYSA-N neopentane Chemical compound CC(C)(C)C CRSOQBOWXPBRES-UHFFFAOYSA-N 0.000 description 2
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 2
- KSCKTBJJRVPGKM-UHFFFAOYSA-N octan-1-olate;titanium(4+) Chemical compound [Ti+4].CCCCCCCC[O-].CCCCCCCC[O-].CCCCCCCC[O-].CCCCCCCC[O-] KSCKTBJJRVPGKM-UHFFFAOYSA-N 0.000 description 2
- 229940049964 oleate Drugs 0.000 description 2
- 238000005191 phase separation Methods 0.000 description 2
- 239000003755 preservative agent Substances 0.000 description 2
- 230000002335 preservative effect Effects 0.000 description 2
- XLCIFRJORZNGEV-UHFFFAOYSA-N propan-2-yl 2-[dodecanoyl(methyl)amino]acetate Chemical compound CCCCCCCCCCCC(=O)N(C)CC(=O)OC(C)C XLCIFRJORZNGEV-UHFFFAOYSA-N 0.000 description 2
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 2
- 235000003441 saturated fatty acids Nutrition 0.000 description 2
- 150000004671 saturated fatty acids Chemical class 0.000 description 2
- 230000037307 sensitive skin Effects 0.000 description 2
- 230000000087 stabilizing effect Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 150000005846 sugar alcohols Polymers 0.000 description 2
- 150000003626 triacylglycerols Chemical class 0.000 description 2
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 description 2
- 150000003628 tricarboxylic acids Chemical class 0.000 description 2
- IIYFAKIEWZDVMP-UHFFFAOYSA-N tridecane Chemical compound CCCCCCCCCCCCC IIYFAKIEWZDVMP-UHFFFAOYSA-N 0.000 description 2
- 150000005691 triesters Chemical class 0.000 description 2
- WEAPVABOECTMGR-UHFFFAOYSA-N triethyl 2-acetyloxypropane-1,2,3-tricarboxylate Chemical compound CCOC(=O)CC(C(=O)OCC)(OC(C)=O)CC(=O)OCC WEAPVABOECTMGR-UHFFFAOYSA-N 0.000 description 2
- 239000001069 triethyl citrate Substances 0.000 description 2
- VMYFZRTXGLUXMZ-UHFFFAOYSA-N triethyl citrate Natural products CCOC(=O)C(O)(C(=O)OCC)C(=O)OCC VMYFZRTXGLUXMZ-UHFFFAOYSA-N 0.000 description 2
- XFNJVJPLKCPIBV-UHFFFAOYSA-N trimethylenediamine Chemical compound NCCCN XFNJVJPLKCPIBV-UHFFFAOYSA-N 0.000 description 2
- DUXYWXYOBMKGIN-UHFFFAOYSA-N trimyristin Chemical compound CCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCC DUXYWXYOBMKGIN-UHFFFAOYSA-N 0.000 description 2
- VLPFTAMPNXLGLX-UHFFFAOYSA-N trioctanoin Chemical compound CCCCCCCC(=O)OCC(OC(=O)CCCCCCC)COC(=O)CCCCCCC VLPFTAMPNXLGLX-UHFFFAOYSA-N 0.000 description 2
- PVNIQBQSYATKKL-UHFFFAOYSA-N tripalmitin Chemical compound CCCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCC PVNIQBQSYATKKL-UHFFFAOYSA-N 0.000 description 2
- RSJKGSCJYJTIGS-UHFFFAOYSA-N undecane Chemical compound CCCCCCCCCCC RSJKGSCJYJTIGS-UHFFFAOYSA-N 0.000 description 2
- 239000008158 vegetable oil Substances 0.000 description 2
- 235000013311 vegetables Nutrition 0.000 description 2
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 description 1
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 1
- NRTKYSGFUISGRQ-UHFFFAOYSA-N (3-heptanoyloxy-2,2-dimethylpropyl) heptanoate Chemical compound CCCCCCC(=O)OCC(C)(C)COC(=O)CCCCCC NRTKYSGFUISGRQ-UHFFFAOYSA-N 0.000 description 1
- MYMRQBXYZBKPAE-UHFFFAOYSA-N (6,6-dihydroxycyclohexa-2,4-dien-1-yl)-phenylmethanone Chemical compound OC1(O)C=CC=CC1C(=O)C1=CC=CC=C1 MYMRQBXYZBKPAE-UHFFFAOYSA-N 0.000 description 1
- YYGNTYWPHWGJRM-UHFFFAOYSA-N (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene Chemical compound CC(C)=CCCC(C)=CCCC(C)=CCCC=C(C)CCC=C(C)CCC=C(C)C YYGNTYWPHWGJRM-UHFFFAOYSA-N 0.000 description 1
- ALSTYHKOOCGGFT-KTKRTIGZSA-N (9Z)-octadecen-1-ol Chemical compound CCCCCCCC\C=C/CCCCCCCCO ALSTYHKOOCGGFT-KTKRTIGZSA-N 0.000 description 1
- JXNPEDYJTDQORS-HZJYTTRNSA-N (9Z,12Z)-octadecadien-1-ol Chemical compound CCCCC\C=C/C\C=C/CCCCCCCCO JXNPEDYJTDQORS-HZJYTTRNSA-N 0.000 description 1
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- CZWWITYVYJRTOX-UHFFFAOYSA-N 1-(2-methylpropoxy)hexadecane Chemical compound CCCCCCCCCCCCCCCCOCC(C)C CZWWITYVYJRTOX-UHFFFAOYSA-N 0.000 description 1
- XMFUMMRWIFOQDQ-UHFFFAOYSA-N 1-(4-methylpentan-2-yloxy)hexadecane Chemical compound CCCCCCCCCCCCCCCCOC(C)CC(C)C XMFUMMRWIFOQDQ-UHFFFAOYSA-N 0.000 description 1
- RWNUSVWFHDHRCJ-UHFFFAOYSA-N 1-butoxypropan-2-ol Chemical compound CCCCOCC(C)O RWNUSVWFHDHRCJ-UHFFFAOYSA-N 0.000 description 1
- JOLQKTGDSGKSKJ-UHFFFAOYSA-N 1-ethoxypropan-2-ol Chemical compound CCOCC(C)O JOLQKTGDSGKSKJ-UHFFFAOYSA-N 0.000 description 1
- ARXJGSRGQADJSQ-UHFFFAOYSA-N 1-methoxypropan-2-ol Chemical compound COCC(C)O ARXJGSRGQADJSQ-UHFFFAOYSA-N 0.000 description 1
- GIEMHYCMBGELGY-UHFFFAOYSA-N 10-undecen-1-ol Chemical compound OCCCCCCCCCC=C GIEMHYCMBGELGY-UHFFFAOYSA-N 0.000 description 1
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 1
- JSOVGYMVTPPEND-UHFFFAOYSA-N 16-methylheptadecyl 2,2-dimethylpropanoate Chemical compound CC(C)CCCCCCCCCCCCCCCOC(=O)C(C)(C)C JSOVGYMVTPPEND-UHFFFAOYSA-N 0.000 description 1
- WLDWSGZHNBANIO-UHFFFAOYSA-N 2',5'-Dihydroxyacetophenone Chemical compound CC(=O)C1=CC(O)=CC=C1O WLDWSGZHNBANIO-UHFFFAOYSA-N 0.000 description 1
- YPTJKHVBDCRKNF-UHFFFAOYSA-N 2',6'-Dihydroxyacetophenone Chemical compound CC(=O)C1=C(O)C=CC=C1O YPTJKHVBDCRKNF-UHFFFAOYSA-N 0.000 description 1
- QFZKSWMAYXNSEJ-UHFFFAOYSA-N 2,3-bis(2-hydroxypropanoyloxy)propyl 2-hydroxypropanoate Chemical compound CC(O)C(=O)OCC(OC(=O)C(C)O)COC(=O)C(C)O QFZKSWMAYXNSEJ-UHFFFAOYSA-N 0.000 description 1
- OBETXYAYXDNJHR-UHFFFAOYSA-N 2-Ethylhexanoic acid Chemical compound CCCCC(CC)C(O)=O OBETXYAYXDNJHR-UHFFFAOYSA-N 0.000 description 1
- XNWFRZJHXBZDAG-UHFFFAOYSA-N 2-METHOXYETHANOL Chemical compound COCCO XNWFRZJHXBZDAG-UHFFFAOYSA-N 0.000 description 1
- FWIUBOWVXREPPL-UHFFFAOYSA-N 2-[2-(7-methyloctanoyloxy)ethoxy]ethyl 7-methyloctanoate Chemical compound CC(C)CCCCCC(=O)OCCOCCOC(=O)CCCCCC(C)C FWIUBOWVXREPPL-UHFFFAOYSA-N 0.000 description 1
- POAOYUHQDCAZBD-UHFFFAOYSA-N 2-butoxyethanol Chemical compound CCCCOCCO POAOYUHQDCAZBD-UHFFFAOYSA-N 0.000 description 1
- TWJNQYPJQDRXPH-UHFFFAOYSA-N 2-cyanobenzohydrazide Chemical compound NNC(=O)C1=CC=CC=C1C#N TWJNQYPJQDRXPH-UHFFFAOYSA-N 0.000 description 1
- ZNQVEEAIQZEUHB-UHFFFAOYSA-N 2-ethoxyethanol Chemical compound CCOCCO ZNQVEEAIQZEUHB-UHFFFAOYSA-N 0.000 description 1
- OUCGJMIVSYHBEC-UHFFFAOYSA-N 2-ethylhexyl 2-ethylhexanoate Chemical compound CCCCC(CC)COC(=O)C(CC)CCCC OUCGJMIVSYHBEC-UHFFFAOYSA-N 0.000 description 1
- NAGVKZOTMXGCCA-UHFFFAOYSA-N 2-ethylhexyl 7-methyloctanoate Chemical compound CCCCC(CC)COC(=O)CCCCCC(C)C NAGVKZOTMXGCCA-UHFFFAOYSA-N 0.000 description 1
- HPUAIVNIHNEYPO-UHFFFAOYSA-N 2-ethylhexyl octanoate Chemical compound CCCCCCCC(=O)OCC(CC)CCCC HPUAIVNIHNEYPO-UHFFFAOYSA-N 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- YSLMWMWTFSOPFR-UHFFFAOYSA-N 3-ethyl-2-(3-ethyl-2-methylpentadecan-2-yl)oxy-2-methylpentadecane Chemical compound C(CCCCCCCCCCC)C(C(C)(C)OC(C(CC)CCCCCCCCCCCC)(C)C)CC YSLMWMWTFSOPFR-UHFFFAOYSA-N 0.000 description 1
- 125000003469 3-methylhexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C([H])([H])* 0.000 description 1
- ZQXRINMCMHCYBD-UHFFFAOYSA-N 4-(2-ethylhexoxy)-4-oxobutanoic acid Chemical compound CCCCC(CC)COC(=O)CCC(O)=O ZQXRINMCMHCYBD-UHFFFAOYSA-N 0.000 description 1
- OBXQRJAQMQQZMY-UHFFFAOYSA-N 4-butoxybutan-1-ol Chemical compound CCCCOCCCCO OBXQRJAQMQQZMY-UHFFFAOYSA-N 0.000 description 1
- QRUOTIJTSNETKW-UHFFFAOYSA-N 4-ethoxybutan-1-ol Chemical compound CCOCCCCO QRUOTIJTSNETKW-UHFFFAOYSA-N 0.000 description 1
- KOVAQMSVARJMPH-UHFFFAOYSA-N 4-methoxybutan-1-ol Chemical compound COCCCCO KOVAQMSVARJMPH-UHFFFAOYSA-N 0.000 description 1
- IBYCEACZVUOBIV-UHFFFAOYSA-N 4-methylpentyl dodecanoate Chemical compound CCCCCCCCCCCC(=O)OCCCC(C)C IBYCEACZVUOBIV-UHFFFAOYSA-N 0.000 description 1
- ODMZDMMTKHXXKA-QXMHVHEDSA-N 8-methylnonyl (z)-octadec-9-enoate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCCCCCCCC(C)C ODMZDMMTKHXXKA-QXMHVHEDSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
- 235000019489 Almond oil Nutrition 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 description 1
- 239000004475 Arginine Substances 0.000 description 1
- LSAACDIRVQTDAU-UHFFFAOYSA-N C(CC(O)(C(=O)O)CC(=O)O)(=O)O.C(CCCCCCC)C(CCCCCCCCCCC)O.C(CCCCCCC)C(CCCCCCCCCCC)O.C(CCCCCCC)C(CCCCCCCCCCC)O Chemical compound C(CC(O)(C(=O)O)CC(=O)O)(=O)O.C(CCCCCCC)C(CCCCCCCCCCC)O.C(CCCCCCC)C(CCCCCCCCCCC)O.C(CCCCCCC)C(CCCCCCCCCCC)O LSAACDIRVQTDAU-UHFFFAOYSA-N 0.000 description 1
- IPPBLYQHJFXJGG-UHFFFAOYSA-N C[Si](C)(C)C(C(C(O)[Si](C)(C)C)(C(O)[Si](C)(C)C)C(O)[Si](C)(C)C)O Chemical compound C[Si](C)(C)C(C(C(O)[Si](C)(C)C)(C(O)[Si](C)(C)C)C(O)[Si](C)(C)C)O IPPBLYQHJFXJGG-UHFFFAOYSA-N 0.000 description 1
- 240000001548 Camellia japonica Species 0.000 description 1
- 239000005632 Capric acid (CAS 334-48-5) Substances 0.000 description 1
- 239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 description 1
- OMPIYDSYGYKWSG-UHFFFAOYSA-N Citronensaeure-alpha-aethylester Natural products CCOC(=O)CC(O)(C(O)=O)CC(O)=O OMPIYDSYGYKWSG-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 description 1
- HMFHBZSHGGEWLO-SOOFDHNKSA-N D-ribofuranose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H]1O HMFHBZSHGGEWLO-SOOFDHNKSA-N 0.000 description 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
- NKOUWLLFHNBUDW-UHFFFAOYSA-N Dipropyl hexanedioate Chemical compound CCCOC(=O)CCCCC(=O)OCCC NKOUWLLFHNBUDW-UHFFFAOYSA-N 0.000 description 1
- 229930091371 Fructose Natural products 0.000 description 1
- 239000005715 Fructose Substances 0.000 description 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- CMBYOWLFQAFZCP-UHFFFAOYSA-N Hexyl dodecanoate Chemical compound CCCCCCCCCCCC(=O)OCCCCCC CMBYOWLFQAFZCP-UHFFFAOYSA-N 0.000 description 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 239000005639 Lauric acid Substances 0.000 description 1
- 235000018330 Macadamia integrifolia Nutrition 0.000 description 1
- 240000000912 Macadamia tetraphylla Species 0.000 description 1
- 235000003800 Macadamia tetraphylla Nutrition 0.000 description 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 235000021360 Myristic acid Nutrition 0.000 description 1
- 241000772415 Neovison vison Species 0.000 description 1
- 239000005642 Oleic acid Substances 0.000 description 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
- 235000019483 Peanut oil Nutrition 0.000 description 1
- 108010009736 Protein Hydrolysates Proteins 0.000 description 1
- 235000019484 Rapeseed oil Nutrition 0.000 description 1
- PYMYPHUHKUWMLA-LMVFSUKVSA-N Ribose Natural products OC[C@@H](O)[C@@H](O)[C@@H](O)C=O PYMYPHUHKUWMLA-LMVFSUKVSA-N 0.000 description 1
- 240000009022 Smilax rotundifolia Species 0.000 description 1
- 235000003205 Smilax rotundifolia Nutrition 0.000 description 1
- 235000021355 Stearic acid Nutrition 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- BHEOSNUKNHRBNM-UHFFFAOYSA-N Tetramethylsqualene Natural products CC(=C)C(C)CCC(=C)C(C)CCC(C)=CCCC=C(C)CCC(C)C(=C)CCC(C)C(C)=C BHEOSNUKNHRBNM-UHFFFAOYSA-N 0.000 description 1
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 description 1
- XSTXAVWGXDQKEL-UHFFFAOYSA-N Trichloroethylene Chemical compound ClC=C(Cl)Cl XSTXAVWGXDQKEL-UHFFFAOYSA-N 0.000 description 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 1
- 239000004904 UV filter Substances 0.000 description 1
- DRRMRHKHTQRWMB-UHFFFAOYSA-N [3-(2-ethylhexanoyloxy)-2,2-bis(2-ethylhexanoyloxymethyl)propyl] 2-ethylhexanoate Chemical compound CCCCC(CC)C(=O)OCC(COC(=O)C(CC)CCCC)(COC(=O)C(CC)CCCC)COC(=O)C(CC)CCCC DRRMRHKHTQRWMB-UHFFFAOYSA-N 0.000 description 1
- RDVFKSXIXOQIDZ-UHFFFAOYSA-N [3-hydroxy-2,2-bis(hydroxymethyl)propyl] 2,2,3,3-tetraethylhexanoate Chemical compound CCCC(CC)(CC)C(CC)(CC)C(=O)OCC(CO)(CO)CO RDVFKSXIXOQIDZ-UHFFFAOYSA-N 0.000 description 1
- YFCGDEUVHLPRCZ-UHFFFAOYSA-N [dimethyl(trimethylsilyloxy)silyl]oxy-dimethyl-trimethylsilyloxysilane Chemical group C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C YFCGDEUVHLPRCZ-UHFFFAOYSA-N 0.000 description 1
- 239000002535 acidifier Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 239000011149 active material Substances 0.000 description 1
- 125000003158 alcohol group Chemical group 0.000 description 1
- 150000001299 aldehydes Chemical class 0.000 description 1
- 229910000288 alkali metal carbonate Inorganic materials 0.000 description 1
- 150000008041 alkali metal carbonates Chemical class 0.000 description 1
- 150000008044 alkali metal hydroxides Chemical class 0.000 description 1
- 229910001860 alkaline earth metal hydroxide Inorganic materials 0.000 description 1
- 125000003342 alkenyl group Chemical group 0.000 description 1
- 239000008168 almond oil Substances 0.000 description 1
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 description 1
- HMFHBZSHGGEWLO-UHFFFAOYSA-N alpha-D-Furanose-Ribose Natural products OCC1OC(O)C(O)C1O HMFHBZSHGGEWLO-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 description 1
- 239000000908 ammonium hydroxide Substances 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- DFYRUELUNQRZTB-UHFFFAOYSA-N apocynin Chemical compound COC1=CC(C(C)=O)=CC=C1O DFYRUELUNQRZTB-UHFFFAOYSA-N 0.000 description 1
- PYMYPHUHKUWMLA-WDCZJNDASA-N arabinose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C=O PYMYPHUHKUWMLA-WDCZJNDASA-N 0.000 description 1
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical class CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 description 1
- 125000001204 arachidyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 235000021302 avocado oil Nutrition 0.000 description 1
- 239000008163 avocado oil Substances 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- 235000019445 benzyl alcohol Nutrition 0.000 description 1
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 description 1
- GFRHRWJBYWRSJE-UHFFFAOYSA-N bis(16-methylheptadecyl) hexanedioate Chemical compound CC(C)CCCCCCCCCCCCCCCOC(=O)CCCCC(=O)OCCCCCCCCCCCCCCCC(C)C GFRHRWJBYWRSJE-UHFFFAOYSA-N 0.000 description 1
- WXNRYSGJLQFHBR-UHFFFAOYSA-N bis(2,4-dihydroxyphenyl)methanone Chemical compound OC1=CC(O)=CC=C1C(=O)C1=CC=C(O)C=C1O WXNRYSGJLQFHBR-UHFFFAOYSA-N 0.000 description 1
- ROPXFXOUUANXRR-YPKPFQOOSA-N bis(2-ethylhexyl) (z)-but-2-enedioate Chemical compound CCCCC(CC)COC(=O)\C=C/C(=O)OCC(CC)CCCC ROPXFXOUUANXRR-YPKPFQOOSA-N 0.000 description 1
- SAOKZLXYCUGLFA-UHFFFAOYSA-N bis(2-ethylhexyl) adipate Chemical compound CCCCC(CC)COC(=O)CCCCC(=O)OCC(CC)CCCC SAOKZLXYCUGLFA-UHFFFAOYSA-N 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- IAQRGUVFOMOMEM-UHFFFAOYSA-N butene Natural products CC=CC IAQRGUVFOMOMEM-UHFFFAOYSA-N 0.000 description 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000010495 camellia oil Substances 0.000 description 1
- SHZIWNPUGXLXDT-UHFFFAOYSA-N caproic acid ethyl ester Natural products CCCCCC(=O)OCC SHZIWNPUGXLXDT-UHFFFAOYSA-N 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 239000011203 carbon fibre reinforced carbon Substances 0.000 description 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 description 1
- 239000004359 castor oil Substances 0.000 description 1
- 235000019438 castor oil Nutrition 0.000 description 1
- 125000002091 cationic group Chemical group 0.000 description 1
- 239000002738 chelating agent Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 235000015165 citric acid Nutrition 0.000 description 1
- 235000018597 common camellia Nutrition 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 235000005687 corn oil Nutrition 0.000 description 1
- 239000002285 corn oil Substances 0.000 description 1
- 125000006165 cyclic alkyl group Chemical group 0.000 description 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 description 1
- 125000005534 decanoate group Chemical class 0.000 description 1
- 125000002704 decyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 150000001983 dialkylethers Chemical class 0.000 description 1
- ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 description 1
- 229940031569 diisopropyl sebacate Drugs 0.000 description 1
- VJHINFRRDQUWOJ-UHFFFAOYSA-N dioctyl sebacate Chemical compound CCCCC(CC)COC(=O)CCCCCCCCC(=O)OCC(CC)CCCC VJHINFRRDQUWOJ-UHFFFAOYSA-N 0.000 description 1
- 150000002009 diols Chemical class 0.000 description 1
- XFKBBSZEQRFVSL-UHFFFAOYSA-N dipropan-2-yl decanedioate Chemical compound CC(C)OC(=O)CCCCCCCCC(=O)OC(C)C XFKBBSZEQRFVSL-UHFFFAOYSA-N 0.000 description 1
- 125000003438 dodecyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 150000002170 ethers Chemical class 0.000 description 1
- 229940057975 ethyl citrate Drugs 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 229930182830 galactose Natural products 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
- 150000002334 glycols Chemical class 0.000 description 1
- 125000003187 heptyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- DWMMZQMXUWUJME-UHFFFAOYSA-N hexadecyl octanoate Chemical compound CCCCCCCCCCCCCCCCOC(=O)CCCCCCC DWMMZQMXUWUJME-UHFFFAOYSA-N 0.000 description 1
- 125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 229940100463 hexyl laurate Drugs 0.000 description 1
- 125000001183 hydrocarbyl group Chemical group 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- LWIGVRDDANOFTD-UHFFFAOYSA-N hydroxy(dimethyl)silane Chemical group C[SiH](C)O LWIGVRDDANOFTD-UHFFFAOYSA-N 0.000 description 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 description 1
- 238000005470 impregnation Methods 0.000 description 1
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 description 1
- 229940078546 isoeicosane Drugs 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- 229940093629 isopropyl isostearate Drugs 0.000 description 1
- 229940074928 isopropyl myristate Drugs 0.000 description 1
- 229940119170 jojoba wax Drugs 0.000 description 1
- 150000002576 ketones Chemical group 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 125000002463 lignoceryl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- JXNPEDYJTDQORS-UHFFFAOYSA-N linoleyl alcohol Natural products CCCCCC=CCC=CCCCCCCCCO JXNPEDYJTDQORS-UHFFFAOYSA-N 0.000 description 1
- 239000000944 linseed oil Substances 0.000 description 1
- 235000021388 linseed oil Nutrition 0.000 description 1
- 210000000088 lip Anatomy 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 125000002960 margaryl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 description 1
- 229940044591 methyl glucose dioleate Drugs 0.000 description 1
- 239000002480 mineral oil Substances 0.000 description 1
- 235000010446 mineral oil Nutrition 0.000 description 1
- 150000007522 mineralic acids Chemical class 0.000 description 1
- 150000002772 monosaccharides Chemical class 0.000 description 1
- 229940105132 myristate Drugs 0.000 description 1
- 125000001421 myristyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 229940078555 myristyl propionate Drugs 0.000 description 1
- AFFLGGQVNFXPEV-UHFFFAOYSA-N n-decene Natural products CCCCCCCCC=C AFFLGGQVNFXPEV-UHFFFAOYSA-N 0.000 description 1
- HWYHDWGGACRVEH-UHFFFAOYSA-N n-methyl-n-(4-pyrrolidin-1-ylbut-2-ynyl)acetamide Chemical compound CC(=O)N(C)CC#CCN1CCCC1 HWYHDWGGACRVEH-UHFFFAOYSA-N 0.000 description 1
- 210000000282 nail Anatomy 0.000 description 1
- 238000006386 neutralization reaction Methods 0.000 description 1
- 125000001196 nonadecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- GSGDTSDELPUTKU-UHFFFAOYSA-N nonoxybenzene Chemical compound CCCCCCCCCOC1=CC=CC=C1 GSGDTSDELPUTKU-UHFFFAOYSA-N 0.000 description 1
- 239000004745 nonwoven fabric Substances 0.000 description 1
- 125000001400 nonyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000010466 nut oil Substances 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 229960002446 octanoic acid Drugs 0.000 description 1
- 125000002347 octyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 229940055577 oleyl alcohol Drugs 0.000 description 1
- XMLQWXUVTXCDDL-UHFFFAOYSA-N oleyl alcohol Natural products CCCCCCC=CCCCCCCCCCCO XMLQWXUVTXCDDL-UHFFFAOYSA-N 0.000 description 1
- 150000002482 oligosaccharides Polymers 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 150000003961 organosilicon compounds Chemical class 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000003002 pH adjusting agent Substances 0.000 description 1
- LBIYNOAMNIKVKF-FPLPWBNLSA-N palmitoleyl alcohol Chemical compound CCCCCC\C=C/CCCCCCCCO LBIYNOAMNIKVKF-FPLPWBNLSA-N 0.000 description 1
- LBIYNOAMNIKVKF-UHFFFAOYSA-N palmitoleyl alcohol Natural products CCCCCCC=CCCCCCCCCO LBIYNOAMNIKVKF-UHFFFAOYSA-N 0.000 description 1
- 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 229940056211 paraffin Drugs 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 239000000312 peanut oil Substances 0.000 description 1
- 125000002958 pentadecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 125000001147 pentyl group Chemical group C(CCCC)* 0.000 description 1
- 239000013500 performance material Substances 0.000 description 1
- 235000011007 phosphoric acid Nutrition 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920000223 polyglycerol Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920005862 polyol Polymers 0.000 description 1
- 150000003077 polyols Chemical class 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- NEOZOXKVMDBOSG-UHFFFAOYSA-N propan-2-yl 16-methylheptadecanoate Chemical compound CC(C)CCCCCCCCCCCCCCC(=O)OC(C)C NEOZOXKVMDBOSG-UHFFFAOYSA-N 0.000 description 1
- 125000002572 propoxy group Chemical group [*]OC([H])([H])C(C([H])([H])[H])([H])[H] 0.000 description 1
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- 239000003531 protein hydrolysate Substances 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 239000003813 safflower oil Substances 0.000 description 1
- 238000007127 saponification reaction Methods 0.000 description 1
- 210000004761 scalp Anatomy 0.000 description 1
- 125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- 239000008159 sesame oil Substances 0.000 description 1
- 235000011803 sesame oil Nutrition 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 229940031439 squalene Drugs 0.000 description 1
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 125000004079 stearyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-N sulfonic acid Chemical compound OS(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-N 0.000 description 1
- 235000020238 sunflower seed Nutrition 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- YRZGMTHQPGNLEK-UHFFFAOYSA-N tetradecyl propionate Chemical compound CCCCCCCCCCCCCCOC(=O)CC YRZGMTHQPGNLEK-UHFFFAOYSA-N 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 125000003944 tolyl group Chemical group 0.000 description 1
- 229940025703 topical product Drugs 0.000 description 1
- 125000002469 tricosyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 125000002889 tridecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 229940118576 triisostearyl citrate Drugs 0.000 description 1
- VMPHSYLJUKZBJJ-UHFFFAOYSA-N trilaurin Chemical compound CCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCC)COC(=O)CCCCCCCCCCC VMPHSYLJUKZBJJ-UHFFFAOYSA-N 0.000 description 1
- 125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- APVVRLGIFCYZHJ-UHFFFAOYSA-N trioctyl 2-hydroxypropane-1,2,3-tricarboxylate Chemical compound CCCCCCCCOC(=O)CC(O)(C(=O)OCCCCCCCC)CC(=O)OCCCCCCCC APVVRLGIFCYZHJ-UHFFFAOYSA-N 0.000 description 1
- COXJMKGEQAWXNP-UHFFFAOYSA-N tris(14-methylpentadecyl) 2-hydroxypropane-1,2,3-tricarboxylate Chemical compound CC(C)CCCCCCCCCCCCCOC(=O)CC(O)(C(=O)OCCCCCCCCCCCCCC(C)C)CC(=O)OCCCCCCCCCCCCCC(C)C COXJMKGEQAWXNP-UHFFFAOYSA-N 0.000 description 1
- ICWQKCGSIHTZNI-UHFFFAOYSA-N tris(16-methylheptadecyl) 2-hydroxypropane-1,2,3-tricarboxylate Chemical compound CC(C)CCCCCCCCCCCCCCCOC(=O)CC(O)(C(=O)OCCCCCCCCCCCCCCCC(C)C)CC(=O)OCCCCCCCCCCCCCCCC(C)C ICWQKCGSIHTZNI-UHFFFAOYSA-N 0.000 description 1
- 125000002948 undecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- 229940099259 vaseline Drugs 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
Landscapes
- Cosmetics (AREA)
Abstract
The present invention relates to a two-phase composition comprising an oil phase comprising (a) at least one oil and an aqueous phase comprising: (b) At least one aromatic ketone compound represented by formula (I); (c) at least one polyglycerin fatty acid ester; and (d) water. The composition according to the invention has two visually distinct phases when not mixed. However, when mixed, the composition according to the invention may be converted into a single phase composition. Single phase compositions, such as emulsions, can provide good cosmetic benefits, such as good make-up removability, without discomfort. The single phase composition can revert to a two phase composition with a clean interface between the two reformed phases.
Description
Technical Field
The present invention relates to a two-phase or biphasic composition having two visually distinct phases and being capable of being converted into a monophasic composition which can be reconverted into a two-phase or biphasic composition.
Background
Compositions having two visually distinct phases (particularly an aqueous phase and an oil phase, which do not emulsify in each other at rest) are commonly referred to as "two-phase" (or "biphasic") compositions. They differ from emulsions in that at rest, the two phases are separated and a single interface is formed between the two phases, rather than multiple interfaces being formed between the continuous phase and each discontinuous phase present in the emulsion.
Such two-phase compositions have been described, for example, in EP-A-370856 and EP-A-603080, in particular for removing makeup from around the eyes.
Preferably, the two-phase composition is stable prior to use, i.e., at rest, so that the appearance and/or odor of the composition remains unchanged over a prolonged period of time under various temperatures and storage conditions.
When used, the two-phase composition needs to be mixed, e.g., shaken, in order to form a single phase composition, e.g., a "temporary" emulsion, which is then applied to keratinous materials, e.g., skin. The single phase composition is required to provide a targeted cosmetic effect, such as good make-up removability. Preferably, if the single phase composition can provide a cosmetic effect without providing discomfort.
On the other hand, after use, i.e. at rest, the single-phase composition must recover its original state by conversion into a two-phase composition, which is called "phase separation". Preferably, the interface between the reformed phases is clean, such that no precipitate is present at the interface.
Thus, there is a need for a two-phase or biphasic composition having two visually distinct phases that is stable when unmixed and that can be converted to a single-phase composition when mixed, wherein the single-phase composition can provide good cosmetic effects, such as good make-up removability, without discomfort, and can return to its original state, i.e., the two-phase or biphasic composition, with a clean interface between the two phases that reform.
DISCLOSURE OF THE INVENTION
It is an object of the present invention to provide a two-phase composition which is stable and which can be converted into a single phase composition when mixed, wherein the single phase composition can provide good cosmetic results, such as good make-up removability, without discomfort, and can revert to a two-phase composition with a clean interface between the two phases being reformed.
The above object is achieved by a two-phase composition comprising:
an oil phase comprising (a) at least one oil; and
an aqueous phase comprising:
(b) At least one aromatic ketone compound represented by the following formula (I)
Wherein the method comprises the steps of
R 5 、R 6 And R is 7 Each independently represents a hydrogen atom, a hydroxyl group, or C 1 -C 6 Alkyl or C 1 -C 6 Alkoxy, provided that R 5 、R 6 And R is 7 At least one of which represents a hydroxyl group, and
r represents C 1 -C 6 Alkyl or aryl;
(c) At least one polyglycerin fatty acid ester; and
(d) And (3) water.
The composition according to the invention can be converted into a single phase composition. Single phase compositions can be converted to two phase compositions.
(a) The oil may be selected from non-polar oils, preferably from hydrocarbon oils, ether oils and mixtures thereof, and more preferably from volatile hydrocarbon oils, ether oils and mixtures thereof.
The amount of (a) the one or more oils in the composition according to the invention may be from 7 to 70% by weight, and preferably from 15 to 65% by weight, relative to the total weight of the composition.
R in formula (I) may represent methyl, ethyl or phenyl, preferably methyl or phenyl, and more preferably methyl.
(b) The aromatic ketone compound may be hydroxyacetophenone, preferably monohydroxyacetophenone, and more preferably 4-hydroxyacetophenone.
The amount of (b) one or more aromatic ketone compounds in the composition according to the invention may be from 0.1 to 3 wt%, preferably from 0.2 to 1 wt%, and more preferably from 0.3 to 0.5 wt%, relative to the total weight of the aqueous phase of the composition.
(c) The polyglycerin fatty acid ester may be selected from polyglycerin fatty acid diesters.
(c) The polyglycerin fatty acid ester may contain 2 to 6 polyglycerin units, preferably 4 to 6 polyglycerin units, and more preferably 5 or 6 polyglycerin units.
(c) The polyglyceryl fatty acid ester may be selected from the group consisting of polyglyceryl-6 dicaprate, polyglyceryl-6 dioleate, polyglyceryl-6 distearate, and mixtures thereof.
The amount of (c) one or more polyglyceryl fatty acid esters in the composition according to the invention may be from 0.001 to 0.5 wt%, preferably from 0.005 to 0.1 wt%, and more preferably from 0.01 to 0.05 wt%, relative to the total weight of the aqueous phase of the composition.
The amount of (d) water in the composition according to the invention may be from 30 to 93% by weight, and preferably from 35 to 85% by weight, relative to the total weight of the composition.
The composition according to the invention may be a cosmetic composition, preferably a cleansing cosmetic composition, and more preferably a cleansing cosmetic composition for the skin and eyelashes.
The invention also relates to a cosmetic method for keratin materials, comprising:
mixing the composition according to the invention to form a single phase composition; and
the monophasic composition is applied to keratin materials.
Best mode for carrying out the invention
The present inventors have diligently studied and found that a two-phase composition which is stable and can be converted into a single-phase composition by mixing at the time of use, wherein the single-phase composition can provide good cosmetic effects such as good make-up removability without discomfort, and can be restored into a two-phase composition at the time of non-use with a clean interface between the two phases reformed, can be provided.
Accordingly, one aspect of the present invention relates to a two-phase composition comprising:
an oil phase comprising (a) at least one oil; and
an aqueous phase comprising:
(b) At least one aromatic ketone compound represented by the following formula (I)
Wherein the method comprises the steps of
R 5 、R 6 And R is 7 Each independently represents a hydrogen atom, a hydroxyl group, or C 1 -C 6 Alkyl or C 1 -C 6 Alkoxy, provided that R 5 、R 6 And R is 7 At least one of which represents a hydroxyl group, and
r represents C 1 -C 6 Alkyl or aryl;
(c) At least one polyglycerin fatty acid ester; and
(d) And (3) water.
The composition according to the invention has two visually distinct phases when not mixed. However, when mixed, the composition according to the invention may be converted into a single phase composition. Single phase compositions, such as emulsions, can provide good cosmetic benefits, such as good make-up removability, without discomfort. The single phase composition can revert to a two phase composition with a clean interface between the two phases that reform.
The composition according to the invention is stable such that it can maintain an oil phase and an aqueous phase, respectively, when not mixed. Thus, the two-phase or biphasic appearance of the composition according to the invention can be maintained during storage or the like of the composition according to the invention.
In particular, the compositions according to the invention are stable, so that the appearance and/or smell of the composition can remain unchanged for a long period of time under various temperatures and storage conditions. For example, the composition according to the invention is stable at lower temperatures, with or without shaking. Thus, the composition according to the invention can be stored well (especially at lower temperatures) even during transportation of automobiles, which can cause vibrations and the like.
When used, the composition according to the invention is mixed. The two phases in the composition according to the invention are an oil phase comprising at least one oil and an aqueous phase comprising water. Thus, when mixing the composition according to the invention, one of the two phases may be dispersed in the other phase to form a visually homogeneous or single phase O/W or W/O composition, such as an O/W or W/O emulsion.
The mixing of the composition according to the invention can be easily carried out. For example, the mixing of the composition according to the invention can be carried out by shaking by hand. After mixing the composition according to the invention, the composition may form a single phase and remain in the single phase for a certain period of time without mixing again.
According to the present invention, a single-phase composition formed from a two-phase composition can provide good cosmetic effects, such as good make-up removability. Thus, the composition according to the invention can be used as a cosmetic composition, preferably a cleansing cosmetic composition, and more preferably a cleansing cosmetic composition for the skin and eyelashes.
Furthermore, single phase compositions formed from the two phase compositions according to the present invention can provide good textures, such as a smooth feel. In addition, it can provide less skin flaking. Skin exfoliation reflects a relatively large loss of the outer layer of the epidermis of the skin and can roughen the skin surface. Thus, the composition according to the present invention may provide a smooth skin finish.
Furthermore, a single phase composition formed from a two phase composition according to the present invention may be more comfortable, e.g., it is less irritating. Thus, the composition according to the invention may be, for example, gentle to the skin, in particular sensitive skin such as the skin around the eyes.
If the two-phase composition according to the invention is transparent prior to mixing, the single-phase composition formed by mixing the two-phase composition may also be transparent.
The single phase composition formed from the two phase composition according to the present invention can be quickly restored to the two phase composition again after a certain period of time by causing the phase separation to re-form two visually distinct phases again. According to the invention, the interface between the two reformed phases can be clean, so that there is no precipitation at the interface.
The composition according to the invention is particularly useful as a makeup remover, preferably for keratin fibres, and more preferably for eyelashes, i.e. mascara.
Hereinafter, the composition according to the present invention will be described in detail.
[ composition ]
(oil)
The composition according to the invention comprises (a) at least one oil. If two or more oils are used, they may be the same or different.
(a) The oil forms the oily phase of the composition according to the invention.
Herein, "oil" refers to a fatty compound or substance that is in liquid or paste (non-solid) form at room temperature (25 ℃) at atmospheric pressure (760 mmHg). As the oil, those commonly used in cosmetology may be used alone or in combination thereof. These oils may be volatile or non-volatile.
The oil may be nonpolar oil such as hydrocarbon oil and symmetric ether oil, silicone oil, etc.; polar oils such as vegetable or animal oils, ester oils and asymmetric ether oils; or a mixture thereof.
The oil may be selected from vegetable or animal origin oils, synthetic oils, silicone oils, hydrocarbon oils and fatty alcohols.
As examples of vegetable oils, mention may be made, for example, of glabrous greenbrier rhizome seed oil, linseed oil, camellia seed oil, macadamia nut oil, corn oil, mink oil, olive oil, avocado oil, camellia oil, castor oil, safflower seed oil, jojoba oil, sunflower seed oil, almond oil, rapeseed oil, sesame oil, soybean oil, peanut oil and mixtures thereof.
As examples of animal oils, squalene and squalane may be mentioned, for example.
As examples of synthetic oils, alkane oils such as isododecane and isohexadecane, ester oils, ether oils and artificial triglycerides may be mentioned.
As an example of the ether oil, dioctyl ether may be mentioned.
The ester oil is preferably saturated or unsaturated, linear or branched C 1 -C 26 Aliphatic mono-or polyacids with saturated or unsaturated, straight-chain or branched C 1 -C 26 Liquid esters of aliphatic monohydric or polyhydric alcohols having a total number of carbon atoms greater than or equal to 10.
Preferably, for esters of monohydric alcohols, at least one of the alcohol and acid from which the esters of the present invention are derived is branched.
Among the monoesters of monoacids and monoalcohols, mention may be made of ethyl palmitate, ethylhexyl palmitate, isopropyl palmitate, dioctyl carbonate, alkyl myristates such as isopropyl myristate or ethyl myristate, isocetyl stearate, 2-ethylhexyl isononanoate, isononyl isononanoate, isodecyl pivalate and isostearyl pivalate.
C can also be used 4 -C 22 Di-or tricarboxylic acids with C 1 -C 22 Esters of alcohols and mono-, di-or tricarboxylic acids with non-sugar C 4 -C 26 Esters of dihydric, trihydric, tetrahydroxy or penta-hydroxy alcohols.
Mention may be made in particular of: diethyl sebacate; isopropyl lauroyl sarcosinate; diisopropyl sebacate; bis (2-ethylhexyl) sebacate; diisopropyl adipate; di-n-propyl adipate; dioctyl adipate; bis (2-ethylhexyl) adipate; diisostearyl adipate; bis (2-ethylhexyl) maleate; triisopropanol citrate; triisocetyl citrate; triisostearyl citrate; glycerol trilactate; glyceryl trioctanoate; tri (octyldodecanol) citrate; triol citrate; neopentyl glycol diheptanoate and diethylene glycol diisononanoate.
As the ester oil, C can be used 6 -C 30 Fatty acids and preferably C 12 -C 22 Sugar esters and diesters of fatty acids. Recall that the term "sugar" refers to an oxygen-containing hydrocarbon-based compound containing several alcohol functions, with or without aldehyde or ketone functions, and which contains at least 4 carbon atoms. These sugars may be mono-, oligo-or polysaccharides.
Examples of suitable sugars that may be mentioned include sucrose (or sucrose), glucose, galactose, ribose, trehalose, maltose, fructose, mannose, arabinose, xylose and lactose, and derivatives thereof, in particular alkyl derivatives such as methyl derivatives, for example methyl glucose.
The sugar esters of fatty acids may in particular be selected from the group consisting of the sugars previously described with linear or branched, saturated or unsaturated C 6 -C 30 Fatty acids and preferably C 12 -C 22 Esters or ester mixtures of fatty acids. If they are unsaturated, these compounds may have one to three conjugated or non-conjugated carbon-carbon double bonds.
The esters according to this variant may also be selected from the group consisting of monoesters, diesters, triesters, tetraesters and polyesters, and mixtures thereof.
These esters may be, for example, oleates, laurates, palmitates, myristates, behenates, cocoates, stearates, linoleates, linolenates, caprates and arachidonates or mixtures thereof, in particular, mixed esters such as oil palmitates, oil stearates and palm stearates, and pentaerythritol tetraethylhexanoate.
More particularly mono-and diesters are used, and in particular sucrose, glucose or methyl glucose mono-or dioleates, stearates, behenates, oil palmitates, linoleates, linolenates and oil stearates.
One example which may be mentioned is the company Amerchol under the nameDO, which is methyl glucose dioleate.
As examples of preferred ester oils mention may be made of, for example, diisopropyl adipate, dioctyl adipate, 2-ethylhexyl caproate, ethyl laurate, cetyl caprylate, octyldodecyl caprylate, isodecyl pivalate, myristyl propionate, 2-ethylhexyl 2-ethylhexanoate, 2-ethylhexyl caprylate/caprate, methyl palmitate, ethyl palmitate, isopropyl palmitate, dioctyl carbonate, isopropyl lauroyl sarcosinate, isononyl isononanoate, ethylhexyl palmitate, isohexyl laurate, hexyl laurate, isocetyl stearate, isopropyl isostearate, isopropyl myristate, isodecyl oleate, tris (2-ethylhexanoate), pentaerythritol tetrakis (2-ethylhexanoate), 2-ethylhexyl succinate, diethyl sebacate and mixtures thereof.
As examples of artificial triglycerides, mention may be made, for example, of caproyl caprylyl glyceride, glyceryl trimyristate, glyceryl tripalmitate, glyceryl trilobate, glyceryl trilaurate, glyceryl tricaprate, glyceryl tricaprylate, glyceryl tris (capric/caprylic) ester (INCI name: caprylic/capric triglyceride) and glyceryl tris (capric/caprylic/linolenic) ester.
As examples of the silicone oil, for example, linear organopolysiloxanes such as polydimethylsiloxane (INCI name: polydimethylsiloxane), methylphenyl polysiloxane, methyl hydrogen polysiloxane, and the like; cyclic organopolysiloxanes such as cyclohexasiloxane, octamethyl cyclotetrasiloxane, decamethyl cyclopentasiloxane, dodecamethyl cyclohexasiloxane, and the like; and mixtures thereof.
Preferably, the silicone oil is selected from liquid polydialkylsiloxanes, in particular liquid Polydimethylsiloxanes (PDMS) and liquid polyorganosiloxanes comprising at least one aryl group.
These silicone oils may also be organically modified. The organomodified silicones which can be used according to the invention are silicone oils as defined above and comprise in their structure one or more organofunctional groups linked via hydrocarbon-based groups.
Organopolysiloxane is defined in more detail in the Academic Press, chemistry and Technology of Silicones by Walter Noll (1968). They may be volatile or non-volatile.
When they are volatile, the silicones are more particularly selected from those having a boiling point of 60 ℃ to 260 ℃, and even more particularly selected from:
(i) Cyclic polydialkylsiloxanes comprising 3 to 7 and preferably 4 to 5 silicon atoms. These are for example given the name Volatile by Union Carbide7207 or by Rhodia under the name +.>70045V2 octamethyl cyclotetrasiloxane, sold under the name Volatile->7158. Under the name Rhodia70045 Decamethyl cyclopentasiloxane sold under the name Silsoft 1217 by V5, and dodecamethyl cyclopentasiloxane sold under the name Silsoft 1217 by Momentive Performance Materials, and mixtures thereof. Mention may also be made of cyclic copolymers (of the type such as dimethylsiloxane/methylalkylsiloxane), such as Silicone +.>FZ 3109 has the formula:
mention may also be made of mixtures of cyclic polydialkylsiloxanes with organosilicon compounds, such as mixtures of octamethyltetrasiloxane and tetrakis (trimethylsilyl) pentaerythritol (50/50), and mixtures of octamethyltetrasiloxane and oxo-1, 1' -bis (2, 2', 3' -hexatrimethylsilyloxy) neopentane; and
(ii) Containing 2 to 9 silicon atoms and having a silicon atom number of less than or equal to 5X 10 at 25 DEG C -6 m 2 Linear volatile polydialkylsiloxane of viscosity/s. One example is decamethyltetrasiloxane sold under the name SH200, particularly by the company Toray Silicone. Silicones belonging to this class are also described in Cosmetics and Toiletries, volume 91, month 1 of 76, pages 27-32, todd&In articles published in Byers, volatile Silicone Fluids for Cosmetics. The viscosity of the silicone was measured at 25 ℃ according to ASTM standard 445 appendix C.
Nonvolatile polydialkylsiloxanes may also be used. These non-volatile silicones are more particularly chosen from polydialkylsiloxanes, among which mention may be made mainly of polydimethylsiloxanes containing trimethylsilyl end groups.
Among these polydialkylsiloxanes, mention may be made, by way of non-limiting example, of the following commercial products:
-series 47 and 70 047 sold by RhodiaOil or->Oils, such as oil 70 047v 500 000;
sold by the company RhodiaA series of oils;
200 series of oils from Dow Corning, inc., such as having a viscosity of 60,000 mm 2 DC200 of/s; and
-come fromFrom General ElectricOils and certain oils from the SF series from General Electric (SF 96, SF 18).
Mention may also be made of polydimethylsiloxanes containing dimethylsilanol end groups known under the name dimethiconol (CTFA), such as the 48 series of oils from Rhodia.
Among the aryl-containing silicones, mention may be made of polydiarylsiloxanes, in particular polydiphenylsiloxanes and polyalkylarylsiloxanes, such as phenyl silicone oils.
The phenyl silicone oil may be selected from phenyl silicones of the formula:
wherein the method comprises the steps of
R 1 To R 10 C-based on straight, cyclic or branched chains, independently of one another, saturated or unsaturated 1 -C 30 Hydrocarbon-based groups, preferably based on C 1 -C 12 Hydrocarbon groups, and more preferably C-based 1 -C 6 Hydrocarbon radicals, in particular methyl, ethyl, propyl or butyl radicals, and
m, n, p and q are each independently an integer from 0 to 900 inclusive, preferably from 0 to 500 inclusive and more preferably from 0 to 100 inclusive,
provided that the sum of n+m+q is not 0.
Examples that may be mentioned include products sold under the following names:
70641 series from RhodiaAn oil;
-from Rhodia70633 and 763 series of oils;
oil from Dow Corning 556Cosmetic Grade Fluid;
silicones from the Bayer PK series, such as product PK20;
certain oils from the SF series of General Electric, such as SF 1023, SF 1154, SF 1250 and SF 1265.
Phenyl-based silicone oil, phenyl-based trimethicone (in the above formula, R 1 To R 10 Is methyl; p, q and n=0; m=1) is preferable.
The organically modified liquid silicone may contain, in particular, polyoxyethylene groups and/or polyoxypropylene groups. Mention may thus be made of the silicones KF-6017 proposed by Shin-Etsu and the oils from the company Union CarbideL722 and L77.
The hydrocarbon oil may be selected from:
-linear or branched, optionally cyclic, C 6 -C 16 Lower alkanes. Examples which may be mentioned include hexane, undecane, dodecane, tridecane and isoparaffins, such as isohexadecane, isododecane and isodecane; and
linear or branched hydrocarbons containing more than 16 carbon atoms, such as liquid paraffin, liquid petrolatum (petrolatum), polydecene and hydrogenated polyisobutene such asAnd squalane.
As preferable examples of the hydrocarbon oil, for example, straight-chain or branched hydrocarbons such as isohexadecane, isododecane, squalane, mineral oil (e.g., liquid paraffin), paraffin, vaseline or petrolatum (petrolatum), naphthalene, and the like; hydrogenated polyisobutene, isoeicosane and decene/butene copolymers; and mixtures thereof.
The term "fat" in fatty alcohols means a compound comprising a relatively large number of carbon atoms. Thus, alcohols having 4 or more, preferably 6 or more, and more preferably 12 or more carbon atoms are included in the range of fatty alcohols. The fatty alcohols may be saturated or unsaturated. The fatty alcohol may be linear or branched.
The fatty alcohol may have the structure R-OH, wherein R is selected from saturated and unsaturated, straight and branched groups containing from 4 to 40 carbon atoms, preferably from 6 to 30 carbon atoms, and more preferably from 12 to 20 carbon atoms. In at least one embodiment, R may be selected from C 12 -C 20 Alkyl and C 12 -C 20 Alkenyl groups. R may or may not be substituted with at least one hydroxy group.
As examples of fatty alcohols, mention may be made of lauryl alcohol, isostearyl alcohol, undecylenol, octyldodecanol, hexyldecanol, oleyl alcohol, linoleyl alcohol, palmitoleyl alcohol, arachidonic alcohol and mixtures thereof.
Thus, the fatty alcohol may be selected from linear or branched, saturated or unsaturated C 6 -C 30 Alcohols, preferably linear or branched saturated C 6 -C 30 Alcohols, and more preferably straight or branched saturated C 12 -C 20 An alcohol.
The term "saturated fatty alcohol" herein refers to an alcohol having a long aliphatic saturated carbon chain. Preferably the saturated fatty alcohol is selected from any linear or branched saturated C 6 -C 30 Fatty alcohols. In straight-chain or branched saturated C 6 -C 30 In fatty alcohols, it is preferable to use saturated C which is linear or branched 12 -C 20 Fatty alcohols. Any straight or branched saturated C may be more preferably used 16 -C 20 Fatty alcohols. Branched C may be used even more preferably 16 -C 20 Fatty alcohols.
As examples of saturated fatty alcohols, mention may be made of lauryl alcohol, isostearyl alcohol, undecylenic alcohol, octyldodecanol, hexyldecanol and mixtures thereof. In one embodiment, octyldodecanol and hexyldecanol may be used as saturated fatty alcohols.
According to at least one embodiment, the fatty alcohol used in the composition according to the invention is preferably chosen from octyldodecanol, hexyldecanol and mixtures thereof.
(a) The oil may be selected from non-polar oils, preferably from hydrocarbon oils, ether oils and mixtures thereof, and more preferably from volatile hydrocarbon oils, ether oils and mixtures thereof.
The volatile hydrocarbon oil may be selected from volatile branched C 8 -C 16 Hydrocarbon oils, preferably selected from isohexadecane, isodecane, isododecane and mixtures thereof.
Preferably, the ether oil is non-volatile. The ether oil may be selected from dialkyl ethers represented by the formula
R 1 -O-R 2
Wherein the method comprises the steps of
R 1 And R is 2 Each independently represents a straight chain, branched chain or cyclic C 4-24 Alkyl, preferably C 6-18 Alkyl, and more preferably C 8-12 An alkyl group. Can preferably be R 1 And R is 2 The same applies.
As straight chain alkyl groups, mention may be made of butyl, pentyl, hexyl, heptyl, octyl, nonyl, decyl, undecyl, dodecyl, tridecyl, tetradecyl, pentadecyl, hexadecyl, heptadecyl, octadecyl, nonadecyl, eicosyl, behenyl, docosyl, tricosyl and tetracosyl.
As the branched alkyl group, there is a branched alkyl group, mention may be made of 1-methylpropyl, 2-methylpropyl, tert-butyl, 1-dimethylpropyl, 3-methylhexyl, 5-methylhexyl, 1-ethylhexyl, 2-ethylhexyl, 1-butylpentyl, 5-methyloctyl, 2-butyloctyl, isotridecyl, 2-pentylnonyl, 2-hexyldecyl, isostearyl, 2-heptylundecyl, 2-octyldodecyl, 1, 3-dimethylbutyl, 1- (1-methylethyl) -2-methylpropyl, 1, 3-tetramethylbutyl, 3, 5-trimethylhexyl, 1- (2-methylpropyl) -3-methylbutyl, 3, 7-dimethyloctyl and 2- (1, 3-trimethylbutyl) -5, 7-trimethyloctyl.
As cyclic alkyl groups, mention may be made of cyclohexyl, 3-methylcyclohexyl and 3, 5-trimethylcyclohexyl.
Preferably, the ether oil is selected from the group consisting of dioctyl ether, didecyl ether, dilauryl ether, diisostearyl ether, dioctyl ether, nonylphenyl ether, dodecyldimethylbutyl ether, cetyl dimethylbutyl ether, cetyl isobutyl ether, and mixtures thereof.
More preferably, the ether oil is selected from the group consisting of dioctyl ether, didecyl ether, dilauryl ether, diisostearyl ether, dioctyl ether, and mixtures thereof.
The amount of (a) oil in the composition according to the invention may be 7% by weight or more, and preferably 15% by weight or more, relative to the total weight of the composition.
The amount of (a) oil in the composition according to the invention may be 70% by weight or less, and preferably 65% by weight or less, relative to the total weight of the composition, provided that the amount of (a) oil is not zero.
The amount of (a) oil in the composition according to the invention may be from 7 to 70% by weight, and preferably from 15 to 65% by weight, relative to the total weight of the composition.
(aromatic Ketone Compound)
The composition according to the invention comprises (b) at least one aromatic ketone compound. If two or more (b) aromatic ketone compounds are used, they may be the same or different.
(b) The aromatic ketone compound is represented by the following formula (I)
Wherein the method comprises the steps of
R 5 、R 6 And R is 7 Each independently represents a hydrogen atom, a hydroxyl group, or C 1 -C 6 Alkyl or C 1 -C 6 Alkoxy, provided that R 5 、R 6 And R is 7 At least one of which represents a hydroxyl group, and
r represents C 1 -C 6 Alkyl or aryl.
As C 1 -C 6 Alkyl groups, for example methyl, ethyl and propyl groups may be mentioned. Methyl is preferred.
As C 1 -C 6 Alkoxy, for example methoxy, ethoxy and propoxy may be mentioned. Methoxy is preferred.
As the aryl group, there may be mentioned, for example, phenyl, substituted phenyl, naphthyl and substituted Is a naphthyl group. As substituents, mention may be made of hydroxy and C 1 -C 6 Alkyl groups such as methyl. Phenyl is preferred.
Preferably, R in the above formula (I) represents methyl, ethyl or phenyl, preferably methyl or phenyl, and more preferably methyl.
As (b) aromatic ketone compounds, there may be mentioned, for example,
2-hydroxy acetophenone, which is a compound of the formula,
3-hydroxy acetophenone, which is a compound of the formula,
4-hydroxyacetophenone,
2, 5-dihydroxyacetophenone,
2, 6-dihydroxyacetophenone,
4-hydroxy-3-methoxyacetophenone,
3,4, 5-trihydroxyacetophenone,
2',2' -dihydroxybenzophenone,
2-hydroxybenzophenone, which is a compound of the formula,
2,2', 4' -tetrahydroxybenzophenone, and
3,4,2',4',6' -pentahydroxybenzophenone.
(b) The aromatic ketone compound is preferably hydroxyacetophenone, more preferably monohydroxyacetophenone, and even more preferably 4-hydroxyacetophenone.
The amount of (b) aromatic ketone compound in the composition according to the present invention may be 0.1% by weight or more, preferably 0.2% by weight or more, and more preferably 0.3% by weight or more, relative to the total weight of the aqueous phase of the composition.
The amount of (b) aromatic ketone compound in the composition according to the invention may be 3 wt% or less, preferably 1 wt% or less, and more preferably 0.5 wt% or less, relative to the total weight of the aqueous phase of the composition, provided that the amount of (b) aromatic ketone compound is not zero.
The amount of (b) aromatic ketone compound in the composition according to the invention may be from 0.1 to 3% by weight, preferably from 0.2 to 1% by weight, and more preferably from 0.3 to 0.5% by weight, relative to the total weight of the aqueous phase of the composition.
The amount of (b) aromatic ketone compound in the composition according to the present invention may be 0.01 wt% or more, preferably 0.05 wt% or more, and more preferably 0.1 wt% or more, relative to the total weight of the composition.
The amount of (b) aromatic ketone compound in the composition according to the invention may be 5 wt% or less, preferably 3 wt% or less, and more preferably 1 wt% or less, relative to the total weight of the composition, provided that the amount of (b) aromatic ketone compound is not zero.
The amount of the (b) aromatic ketone compound in the composition according to the invention may be 0.01 to 5 wt%, preferably 0.05 to 3 wt%, and more preferably 0.1 to 1 wt%, relative to the total weight of the composition.
(polyglycerol fatty acid ester)
The composition according to the invention comprises (c) at least one polyglyceryl fatty acid ester. If two or more of the (c) polyglycerin fatty acid esters are used, they may be the same or different.
(c) The polyglycerin fatty acid ester may be selected from monoesters, diesters and triesters of linear or branched saturated or unsaturated fatty acids, preferably saturated fatty acids, which contain 2 to 28 carbon atoms, preferably 4 to 20 carbon atoms, and more preferably 6 to 12 carbon atoms, such as lauric acid, oleic acid, stearic acid, isostearic acid, capric acid, caprylic acid and myristic acid.
Preferably (c) the polyglycerin fatty acid ester has polyglycerin moieties from 2 to 6 glycerins, more preferably 4 to 6 glycerins, and even more preferably 5 or 6 glycerins. In other words, it is preferable that (c) the polyglycerin fatty acid ester contains 2 to 6 polyglycerin units, more preferably 4 to 6 polyglycerin units, and even more preferably 5 or 6 polyglycerin units.
In the composition according to the invention, (c) the polyglycerin fatty acid ester is present in the aqueous phase. Thus, (c) the polyglycerin fatty acid ester is relatively hydrophilic.
Thus, (c) the HLB (hydrophilic-lipophilic balance) value of the polyglycerin fatty acid ester may be 8.0 or more, preferably 9.0 or more, and more preferably 10.0 or more. If two or more polyglycerin fatty acid esters are used, the HLB value is determined from a weighted average of the HLB values of all polyglycerin fatty acid esters.
The term HLB ("hydrophilic-lipophilic balance") is well known to those skilled in the art and reflects the ratio between hydrophilic and lipophilic portions of a molecule. The HLB value can be calculated using the following formula: hlb=20 x (1-S/a), where S is the saponification value of the ester and a is the neutralization value of the fatty acid.
(c) The polyglycerin fatty acid ester may be selected from polyglycerin fatty acid monoesters.
The HLB value of the polyglycerin fatty acid monoester may be 8.0 to 17.0, preferably 9.0 to 16.0, and more preferably 10.0 to 15.0. If two or more polyglycerin fatty acid monoesters are used, the HLB value is determined by a weighted average of the HLB values of all polyglycerin fatty acid monoesters.
The polyglyceryl fatty acid monoester may be selected from the group consisting of PG4 oleate (HLB: 8.8), PG4 laurate (HLB: 10.3), PG4 isostearate (HLB: 8.2), PG5 laurate (HLB: 10.5), PG6 isostearate (HLB: 10.8), PG4 caprylate (HLB: 14), PG4 caprate (HLB: about 15), PG5 myristate (HLB: 15.4), PG5 stearate (HLB: 15), PG5 oleate (HLB: 12.2), PG6 caprylate (HLB: 14.6), PG6 caprate (HLB: 13.1), PG6 laurate (HLB: 14.1), and mixtures thereof.
Preferably (c) the polyglycerin fatty acid ester is selected from polyglycerin fatty acid diesters.
The HLB value of the polyglycerin fatty acid diester may be 8.0 to 13.0, preferably 9.0 to 12.0, and more preferably 10.0 to 11.0. If two or more polyglyceryl fatty acid diesters are used, the HLB value is determined by a weighted average of the HLB values of all polyglyceryl fatty acid diesters.
The polyglyceryl fatty acid diester may be selected from the group consisting of PG-6 distearate (HLB: 8), PG-6 dioleate (HLB: 9.8), PG-6 didecanoate (HLB: 10.2), and mixtures thereof.
As PG6 dicaprate, for example, sunsoft Q-102H-C sold by Taiyo Kagaku Co., ltd. As PG6 dioleate, sunsoft Q-172H-C sold by Taiyo Kagaku Co.Ltd. As PG6 distearate, emalex DSG-6 sold by Nihon Emulsion Co., ltd.
The amount of the (c) polyglycerin fatty acid ester in the composition according to the present invention may be 0.001% by weight or more, preferably 0.005% by weight or more, and more preferably 0.01% by weight or more, relative to the total weight of the aqueous phase of the composition.
The amount of (c) polyglycerin fatty acid ester in the composition according to the present invention may be 0.5% by weight or less, preferably 0.1% by weight or less, and more preferably 0.05% by weight or less, relative to the total weight of the aqueous phase of the composition, provided that the amount of (c) polyglycerin fatty acid ester is not zero.
The amount of (c) polyglyceryl fatty acid ester in the composition according to the present invention may be from 0.001 to 0.5 wt%, preferably from 0.005 to 0.1 wt%, and more preferably from 0.01 to 0.05 wt%, relative to the total weight of the aqueous phase of the composition.
The amount of (c) polyglycerin fatty acid ester in the composition according to the present invention may be 0.0001% by weight or more, preferably 0.0005% by weight or more, and more preferably 0.001% by weight or more, relative to the total weight of the composition.
The amount of (c) polyglycerin fatty acid ester in the composition according to the present invention may be 1% by weight or less, preferably 0.5% by weight or less, and more preferably 0.1% by weight or less, relative to the total weight of the composition, provided that the amount of (c) polyglycerin fatty acid ester is not zero.
The amount of (c) polyglyceryl fatty acid ester in the composition according to the present invention may be from 0.0001 wt% to 1 wt%, preferably from 0.0005 wt% to 0.5 wt%, and more preferably from 0.001 wt% to 0.1 wt%, relative to the total weight of the composition.
(Water)
The composition according to the invention comprises (d) water.
(d) Water can form the aqueous phase of the composition according to the invention.
The amount of (d) water in the composition according to the invention may be 30% by weight or more, and preferably 35% by weight or more, relative to the total weight of the composition.
The amount of (d) water in the composition according to the invention may be 93 wt% or less, and preferably 85 wt% or less, with respect to the total weight of the composition, provided that the amount of (d) water is not zero.
The amount of (d) water in the composition according to the invention may be from 30 to 93% by weight, and preferably from 35 to 85% by weight, relative to the total weight of the composition.
(citrate ester)
The composition according to the invention may comprise (e) at least one citrate ester. If two or more citrates are used, they may be the same or different.
(e) The citrate esters may be represented by the following chemical formula (I):
wherein the method comprises the steps of
R 1 、R 2 And R is 3 Independently represents a hydrogen atom, a saturated or unsaturated straight or branched C 1 -C 30 Hydrocarbyl, or saturated or unsaturated cyclic C 3 -C 30 Hydrocarbyl radicals, wherein R 1 、R 2 And R is 3 At least one of which is not a hydrogen atom, and
R 4 represents a hydrogen atom or R' 4 -CO-groups, wherein R' 4 Represents saturated or unsaturated, straight-chain or branched C 1 -C 8 Hydrocarbon radicals, or saturated or unsaturated cyclic C 3 -C 8 A hydrocarbon group.
Preferably R 1 、R 2 And R is 3 C being wholly saturated or unsaturated, straight-chain or branched 1 -C 30 Hydrocarbon radicals, or saturated or unsaturated cyclic C 3 -C 30 Hydrocarbon radicals, more preferably saturated or unsaturated, straight-chain or branched C 1 -C 30 Hydrocarbon radicals, and even more preferably straight-chain or branched C 1 -C 30 An alkyl group.
Preferably R 4 Is a hydrogen atom or R' 4 -CO-groups, wherein R' 4 Represents saturated or unsaturated, straight-chain or branched C 1 -C 8 Hydrocarbyl radicals, more preferably hydrogen atoms or R' 4 -CO-groups, wherein R' 4 C represents a straight or branched chain 1 -C 8 Alkyl groups, and even more preferably hydrogen atoms or R' 4 -CO-groups, wherein R' 4 Represents methyl.
It may be preferred that (e) the citrate ester is selected from the group consisting of triethyl citrate, tributyl citrate, trioctyl citrate, acetyl triethyl citrate, acetyl tributyl citrate, acetyl tri (2-ethylhexyl) citrate, and mixtures thereof, more preferably triethyl citrate, tributyl citrate, acetyl triethyl citrate, acetyl tributyl citrate, and mixtures thereof, and even more preferably ethyl citrate.
The amount of (e) one or more citric acid esters in the composition according to the invention may be 0.1% by weight or more, preferably 0.5% by weight or more, and more preferably 1% by weight or more, relative to the total weight of the composition.
The amount of (e) one or more citric acid esters in the composition according to the invention may be 15 wt.% or less, preferably 10 wt.% or less, and more preferably 5 wt.% or less, relative to the total weight of the composition, provided that the amount of (b) one or more citric acid esters is not zero.
The amount of (e) one or more citric acid esters in the composition according to the invention may be from 0.1 to 15% by weight, preferably from 0.5 to 10% by weight, and more preferably from 1 to 5% by weight, relative to the total weight of the composition.
(cosmetic active ingredient)
The composition according to the invention may comprise at least one cosmetically active ingredient. A single type of cosmetic active ingredient, or two or more different types of cosmetic active ingredients, may be used in combination.
The cosmetically active ingredient may preferably be water-insoluble or oil-insoluble.
The amount of cosmetically active ingredient in the composition according to the invention may be 0.1% by weight or more, preferably 0.5% by weight or more, and more preferably 1% by weight or more, relative to the total weight of the composition.
The amount of cosmetically active ingredient in the composition according to the invention may be 30% by weight or less, preferably 25% by weight or less, and more preferably 20% by weight or less, with respect to the total weight of the composition, provided that the amount of cosmetically active ingredient is not zero.
The amount of cosmetically active ingredient in the composition according to the invention may be from 0.1% to 30% by weight, preferably from 0.5% to 25% by weight, and more preferably from 1% to 20% by weight, relative to the total weight of the composition.
(surfactant)
The composition according to the invention may comprise at least one further surfactant different from the (c) polyglyceryl fatty acid ester. If two or more additional surfactants are used, they may be the same or different.
However, it may be preferred that the amount of additional surfactant is small.
The amount of additional surfactant may be 1 wt% or less, preferably 0.5 wt% or less, and more preferably 0.3 wt% or less, relative to the total weight of the composition according to the invention. It is particularly preferred that the composition according to the invention does not comprise further surfactants.
(other Components)
The composition according to the invention may also comprise at least one optional or additional ingredient.
The amount of one or more optional or additional ingredients is not limited, but may be from 0.01 wt% to 30 wt%, preferably from 0.1 wt% to 20 wt%, and more preferably from 1 wt% to 10 wt%, relative to the total weight of the composition according to the invention.
Optionally or additionally one or more ingredients may be selected from anionic, cationic, nonionic or amphoteric polymers; organic or inorganic UV filters; peptides and derivatives thereof; protein hydrolysates; a swelling agent; a penetrant; a thickener; a suspending agent; a chelating agent; a light-shielding agent; a dye; vitamins or provitamins; a fragrance; preservative, auxiliary preservative and stabilizer; and mixtures thereof.
The composition according to the invention may comprise one or several cosmetically acceptable organic solvents, which may be alcohols: in particular monovalent alcohols such as ethanol, isopropanol, benzyl alcohol and phenethyl alcohol; diols such as ethylene glycol, propylene glycol, and butylene glycol; other polyols such as glycerol, sugars and sugar alcohols; and ethers such as ethylene glycol monomethyl ether, ethylene glycol monoethyl ether and ethylene glycol monobutyl ether, propylene glycol monomethyl ether, propylene glycol monoethyl ether and propylene glycol monobutyl ether, and butylene glycol monomethyl ether, butylene glycol monoethyl ether and butylene glycol monobutyl ether.
The concentration of the one or more organic solvents may be from 0.01 wt% to 20 wt%, preferably from 0.1 wt% to 15 wt%, and more preferably from 1 wt% to 10 wt%, relative to the total weight of the composition.
The pH of the composition according to the invention can be controlled. The pH may be, for example, 3 to 11, preferably 3.5 to 9, and more preferably 4 to 7. The pH can be adjusted to the desired value using at least one acidifying agent and/or at least one alkalizing agent.
The acidulant may be, for example, an inorganic or organic acid such as hydrochloric acid, orthophosphoric acid, carboxylic acid such as tartaric acid, citric acid, lactic acid or sulphonic acid.
The alkalizing agent may be, for example, ammonium hydroxide, alkali metal hydroxide, alkaline earth metal hydroxide, alkali metal carbonate, alkanolamines such as monoethanolamine, diethanolamine and triethanolamine, and their derivatives, preferably sodium hydroxide or potassium hydroxide and compounds of the formula:
wherein the method comprises the steps of
R represents optionally hydroxy or C 1 -C 4 Alkyl-substituted alkylene groups such as propylene, and R 1 、R 2 、R 3 And R is 4 Independently represents a hydrogen atom, an alkyl group or C 1 -C 4 Examples of the "hydroxyalkyl" may include 1, 3-propanediamine and derivatives thereof. Arginine, urea and monoethanolamine may be preferred.
The acidifying or alkalizing agent may be present in an amount of less than 5% by weight, preferably 1% by weight or less, and more preferably 0.1% by weight or less, relative to the total weight of the composition.
(form)
The composition according to the invention may have two visually distinct phases. One of the two phases is an oil phase and the other is an aqueous phase.
The amount of oil phase in the composition according to the invention may be 20 wt% or more, preferably 30 wt% or more, and more preferably 40 wt% or more, relative to the total weight of the composition.
The amount of oil phase in the composition according to the invention may be 80 wt% or less, preferably 70 wt% or less, and more preferably 60 wt% or less, relative to the total weight of the composition, provided that the amount of oil phase is not zero.
The amount of oil phase in the composition according to the invention may be from 20 to 80% by weight, preferably from 30 to 70% by weight, and more preferably from 40 to 60% by weight, relative to the total weight of the composition.
The oil phase comprises (a) at least one oil as described above.
The amount of (a) at least one oil in the oil phase may be 85 wt% or more, preferably 90 wt% or more, and more preferably 95 wt% or more, relative to the total weight of the oil phase.
The amount of aqueous phase in the composition according to the invention may be 20% by weight or more, preferably 30% by weight or more, and more preferably 40% by weight or more, relative to the total weight of the composition.
The amount of aqueous phase in the composition according to the invention may be 80% by weight or less, preferably 70% by weight or less, and more preferably 60% by weight or less, relative to the total weight of the composition, provided that the amount of oil phase is not zero.
The amount of aqueous phase in the composition according to the invention may be from 20 to 80% by weight, preferably from 30 to 70% by weight, and more preferably from 40 to 60% by weight, relative to the total weight of the composition.
The aqueous phase comprises (b) at least one aromatic ketone compound, (c) at least one polyglycerin fatty acid ester, and (d) water.
The amount of (d) water in the aqueous phase may be 85% by weight or more, preferably 90% by weight or more, and more preferably 95% by weight or more, relative to the total weight of the aqueous phase.
Furthermore, the aqueous phase may comprise at least one further hydrophilic component. In one embodiment, the aqueous phase may comprise at least one pH adjusting agent such as acids and bases, and/or at least one organic solvent such as glycols.
When mixed, the composition according to the invention may be converted into a single phase composition. The composition according to the invention after mixing may be of the O/W type or of the W/O type, preferably in the form of an O/W or W/O liquid composition, and more preferably in the form of an O/W or W/O emulsion.
If the specific gravity of the oil phase is smaller than that of the aqueous phase, in the composition according to the invention the oil phase is present above the aqueous phase. Typically, the oil phase is present on top of the stationary aqueous phase, as the specific gravity of the oil tends to be less than that of water.
[ preparation ]
The composition according to the invention may be prepared by: the oil phase is formed by: providing (a) an oil or mixing ingredients comprising (a) one or more oils as an oil phase, forming an aqueous phase by: the components comprising (b) an aromatic ketone compound, (c) a polyglycerin fatty acid ester, and (d) water are mixed as an aqueous phase, and the oil phase and the aqueous phase are combined.
For example, the composition according to the present invention may be prepared by a process comprising:
(i) Providing or mixing
(a) At least one oil
Forming an oil phase with at least one optional ingredient;
(ii) Mixing
(b) At least one aromatic ketone compound;
(c) At least one polyglycerin fatty acid ester; and
(d) Water and its preparation method
Forming an aqueous phase with at least one optional ingredient; and
(iii) The oil phase and the water phase are combined.
The mixing step may be carried out by any conventional method.
The step of combining the oil and water phases is preferably performed gently so that the oil and water phases are slowly poured into a vessel such as a container.
[ use and method ]
When the composition according to the invention is used, it is mixed by shaking (hand shaking) for example by hand. After mixing the composition according to the invention, the composition may form a single phase composition. A single phase composition may be applied to the keratin materials to perform a targeted cosmetic effect.
The keratin materials may be skin, nails, mucous membranes such as lips, or keratin fibers such as eyebrows and eyelashes.
The composition according to the invention may preferably be used as a cosmetic composition, more preferably a cleansing cosmetic composition, and even more preferably a cleansing cosmetic composition for the skin and eyelashes.
The composition according to the invention may provide a cosmetic effect, such as makeup removal.
The composition according to the invention may also provide a good texture, such as a smooth feel, and thus it may provide a smooth skin finish.
The composition according to the invention is comfortable because it is less irritating and it is gentle on the skin, in particular on sensitive skin, for example on the skin around the eyes.
The skin herein includes facial skin, neck skin and scalp. The composition according to the invention may also be applied to mucous membranes, such as the lips.
The composition according to the invention may be used as such (as a topical product) or may be used by impregnation into a porous substrate such as a nonwoven fabric, preferably made of cellulosic fibres such as cotton.
In particular, the composition according to the invention may be intended for application to keratin materials such as the skin, the lips, the eyebrows and the eyelashes. Thus, the composition according to the invention can be used in a cosmetic method for keratin materials such as the skin, lips, eyebrows and eyelashes, preferably the skin and eyelashes.
The composition according to the invention can be used for care or cleaning, not for making up keratin materials. Preferably, the composition according to the invention is used in skin care products such as lotions or cleaning products such as make-up removers, rather than in cosmetic products such as foundations. Preferably, the composition according to the invention does not comprise iron oxide or comprises iron oxide in an amount of 0.5 wt% or less, more preferably 0.2 wt% or less, even more preferably 0.1 wt% or less, relative to the total weight of the composition according to the invention.
The cosmetic process for keratin materials according to the invention may comprise at least the following steps
Mixing the composition according to the invention to form a single phase composition; and
The monophasic composition is applied to keratin materials.
Single phase compositions do not have two visually distinct phases. In contrast, single phase compositions have a single phase, which is typically an emulsion phase. The emulsion phase may be opaque, but it may be translucent or opaque.
The invention may relate to
(b) At least one aromatic ketone compound, and
(c) At least one polyglycerin fatty acid ester;
in a two-phase composition comprising an aqueous phase comprising (d) water and an oil phase comprising (a) an oil, for stabilizing the composition, in particular at a lower temperature, for example 4 ℃, and/or for making the composition less irritating.
In addition, the invention also relates to
(b) At least one aromatic ketone compound, and
(c) At least one polyglycerin fatty acid ester;
in a two-phase composition comprising an aqueous phase comprising (d) water and an oil phase comprising (a) oil for stabilizing the composition, in particular at a lower temperature, for example 4 ℃, such that there is no precipitation at the interface between the oil phase and the aqueous phase, which interface is reformed after mixing the two-phase composition, and/or such that the composition is less irritating, in particular for use with less irritating skin around the eyes.
Examples
The present invention will be described in more detail by way of examples. However, these examples should not be construed as limiting the scope of the invention. The following examples are given as non-limiting illustrations of the field of the invention.
Examples 1 to 7 and comparative examples 1 to 5
The following compositions according to examples 1-7 and comparative examples 1-5 shown in Table 1 were prepared by mixing the ingredients shown in Table 1 below.
(1) Mixing the oil phase preparation (OP preparation in table 1) ingredients at about 25 ℃ to form a homogeneous mixture of oil phase ingredients;
(2) Mixing the aqueous phase preparation (AP preparation in table 1) ingredients at about 60 ℃ to form a homogeneous mixture of aqueous phase preparation ingredients; and
(3) For each composition, the above ingredients were prepared in the aqueous phase, then the order of the ingredients prepared in the oil phase was poured into a package, and mixed.
Preparing an oil phase: the actual mixing weight ratio for the aqueous phase preparation was 50:50 for examples 1-6 and comparative examples 1-5 and 15:85 for example 7.
It should be noted that "hydroxyacetophenone" refers to 4-hydroxyacetophenone.
The values of the amounts of the components shown in table 1 are all based on "% by weight" as active material.
TABLE 1
OP: oil phase AP: aqueous phase
TABLE 2
[ evaluation ]
The compositions according to examples 1 to 7 and comparative examples 1 to 5 were evaluated as follows.
(make-up removability)
Each of the 5 panelists made up their lashes by applying a mascara product (MAYBELLINE volume' Express Hypercurl Waterproof N01 Black) to the lashes with the brush head in a total of 40 strokes (each time the brush head is immersed in a bottle containing the mascara product).
4mL of each of the compositions according to examples 1-7 and comparative examples 1-5 was shaken to form an emulsion. By using cotton sheets, the emulsion was applied to the skin around the eyes by massaging for 30 seconds with circular motion of the cotton sheets around the eyes.
Panelists rated the makeup removability, with grades 1 (very poor) to 5 (excellent), and the average values of the evaluations were classified according to the following criteria.
Excellent (5.0 to 4.0): no mascara residue was observed at all.
Good (3.9 to 3.0): little mascara residue was observed.
Poor (2.9 to 2.0): mascara residue was slightly observed.
Very poor (1.9 to 1.0): mascara residue was observed.
The results are shown in Table 2.
(transparency)
The transparency of each composition according to examples 1 to 7 and comparative examples 1 to 5 immediately after preparation (before shaking) was examined.
The results are shown in Table 2.
(transparency after shaking)
The transparency of each of the compositions according to examples 1 to 7 and comparative examples 1 to 5 after shaking at 4℃for one week was examined.
The results are shown in Table 2.
(interfacial precipitation)
The compositions according to examples 1 to 7 and comparative examples 1 to 5 were examined for the presence of interfacial precipitation between the oil phase and the water phase after shaking at 4℃for one week.
The results are shown in Table 2.
(skin exfoliation)
4mL of each of the compositions according to examples 1-7 and comparative examples 1-5 was shaken to form an emulsion. Using cotton sheets, the emulsion was applied to the skin around the eyes by massaging the eyes with a circular motion of the cotton sheets around the eyes for 30 seconds.
Panelists evaluated the degree of skin exfoliation, using a scale of 1 (skin exfoliation is more pronounced) to 5 (skin exfoliation is less pronounced), and the scores of the scales were averaged.
The results are shown in Table 2.
(mildness to the eye)
4mL of each of the compositions according to examples 1-7 and comparative examples 1-5 was shaken to form an emulsion. Using cotton sheets, the emulsion was applied to the skin around the eyes by massaging the eyes with a circular motion of the cotton sheets around the eyes for 30 seconds.
Panelists rated the discomfort during the above administration, with grades 1 (very uncomfortable) to 5 (no discomfort), and the scores of the grades were averaged.
The results are shown in Table 2.
(demulsification speed)
The respective compositions according to examples 1 to 7 and comparative examples 1 to 5 were filled into transparent glass bottles. The clear bottle was shaken very well to form an emulsion. The clear bottle was left to stand (resting) and the time for the emulsion to completely disappear to form two visually distinct phases was measured.
The results are shown in Table 2.
(stability)
The respective compositions according to examples 1 to 7 and comparative examples 1 to 5 were filled into transparent glass bottles. The clear bottle was maintained at a temperature of 4 ℃, 25 ℃ and 45 ℃ for 2 months. The vials were kept stationary or shaken daily at 4 ℃.
After 2 months, each composition was examined in terms of transparency, color and smell, and evaluated according to the following criteria.
Excellent: almost the same as in production.
Good: minor changes in transparency, color and odor were observed.
Poor: the changes in transparency, color and smell were clearly observed. The appearance of precipitation or turbidity was also clearly observed.
Very poor: the changes in transparency, color and smell are clearly observed. A precipitate or cloudy appearance is also clearly observed.
The results are shown in Table 2.
(smoothness)
4mL of each of the compositions according to examples 1-7 and comparative examples 1-5 was shaken to form an emulsion. Using cotton sheets, the emulsion was applied to the skin around the eyes by massaging the eyes with a circular motion of the cotton sheets around the eyes for 30 seconds.
Panelists evaluated the smoothness of the skin after the above application, with grades 1 (very matte = tacky) to 5 (very smooth), and the scores of the grades were averaged.
The results are shown in Table 2.
(summary)
Examples 1-7 demonstrate that the combined use of hydroxyacetophenone (4-hydroxyacetophenone) and polyglycerol-6 dicaprate in the aqueous phase of a two-phase composition comprising an oil phase and an aqueous phase contributes to good stability of the two-phase composition, in particular at lower temperatures; and mildness to the skin around the eyes, high make-up removal effectiveness, and smooth skin finish (and less skin flaking) of the single phase composition formed from the two phase composition, and the single phase composition is able to quickly revert to the two phase composition with a clean interface between the two reformed phases.
Comparative example 1 shows that the absence of polyglycerol-6-dicaprate deteriorates the stability at lower temperatures, such as 4 ℃, and that small precipitates occur at the interface between the two reformed phases.
Comparative examples 2 and 3 show that no hydroxyacetophenone was used to cause a strong discomfort around the eyes.
Comparative examples 4 and 5 show that the use of other types of surfactants instead of polyglycerol-6-dicaprate deteriorates the stability at lower temperatures, such as 4 c, and that small precipitates appear at the interface between the two reformed phases. In addition, comparative examples 4 and 5 caused discomfort around the eyes.
Claims (15)
1. A two-phase composition comprising
An oil phase comprising (a) at least one oil, and
an aqueous phase comprising:
(b) At least one aromatic ketone compound represented by the following formula (I)
Wherein the method comprises the steps of
R 5 、R 6 And R is 7 Each independently represents a hydrogen atom, a hydroxyl group, or C 1 -C 6 Alkyl or C 1 -C 6 Alkoxy, provided that R 5 、R 6 And R is 7 At least one of which represents a hydroxyl group, and
r represents C 1 -C 6 Alkyl or aryl;
(c) At least one polyglycerin fatty acid ester; and
(d) And (3) water.
2. The composition of claim 1, wherein the composition is capable of being converted to a single phase composition.
3. The composition of claim 2, wherein the single phase composition is capable of being converted to a two phase composition.
4. A composition according to any one of claims 1 to 3, wherein (a) the oil is selected from non-polar oils, preferably from hydrocarbon oils, ether oils and mixtures thereof, and more preferably from volatile hydrocarbon oils, ether oils and mixtures thereof.
5. The composition according to any one of claims 1 to 4, wherein the amount of (a) one or more oils in the composition is from 7 to 70 wt%, and preferably from 15 to 65 wt%, relative to the total weight of the composition.
6. A composition according to any one of claims 1 to 5, wherein R in formula (I) represents methyl, ethyl or phenyl, preferably methyl or phenyl, and more preferably methyl.
7. The composition according to any one of claims 1 to 6, wherein (b) the aromatic ketone compound is hydroxyacetophenone, preferably monohydroxyacetophenone, and more preferably 4-hydroxyacetophenone.
8. The composition according to any one of claims 1 to 7, wherein the amount of (b) one or more aromatic ketone compounds in the composition is from 0.1 to 3 wt%, preferably from 0.2 to 1 wt%, and more preferably from 0.3 to 0.5 wt%, relative to the total weight of the aqueous phase of the composition.
9. The composition of any one of claims 1 to 8, wherein (c) the polyglycerin fatty acid ester is selected from polyglycerin fatty acid diesters.
10. The composition according to any one of claims 1 to 9, wherein (c) the polyglycerin fatty acid ester comprises 2-6 polyglycerin units, preferably 4-6 polyglycerin units, and more preferably 5 or 6 polyglycerin units.
11. The composition of any one of claims 1 to 10, wherein (c) the polyglyceryl fatty acid ester is selected from the group consisting of polyglyceryl-6 dicaprate, polyglyceryl-6 dioleate, polyglyceryl-6 distearate, and mixtures thereof.
12. The composition according to any one of claims 1 to 11, wherein the amount of (c) one or more polyglycerin fatty acid esters in the composition is 0.001 to 0.5 wt%, preferably 0.005 to 0.1 wt%, and more preferably 0.01 to 0.05 wt%, relative to the total weight of the aqueous phase of the composition.
13. The composition according to any one of claims 1 to 12, wherein the amount of (d) water in the composition is from 30 to 93 wt%, preferably from 35 to 85 wt%, relative to the total weight of the composition.
14. The composition according to any one of claims 1 to 13, wherein the composition is a cosmetic composition, preferably a cleansing cosmetic composition, and more preferably a cleansing cosmetic composition for skin and eyelashes.
15. A cosmetic method for keratin materials, comprising:
mixing the composition of any one of claims 1 to 14 to form a single phase composition; and
the monophasic composition is applied to keratin materials.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020162247A JP2022054953A (en) | 2020-09-28 | 2020-09-28 | Two-phase composition |
| JP2020-162247 | 2020-09-28 | ||
| FR2011047 | 2020-10-28 | ||
| PCT/JP2021/034209 WO2022065207A1 (en) | 2020-09-28 | 2021-09-10 | Two-phase composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116490162A true CN116490162A (en) | 2023-07-25 |
Family
ID=80997814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202180078362.0A Pending CN116490162A (en) | 2020-09-28 | 2021-09-10 | Two-phase composition |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JP2022054953A (en) |
| CN (1) | CN116490162A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107072898A (en) * | 2014-06-25 | 2017-08-18 | 莱雅公司 | Composition in the form of a nanoemulsion or microemulsion or with a layered structure |
| CN107997996A (en) * | 2017-12-12 | 2018-05-08 | 广州市仙婷贸易有限公司 | A kind of bilayer mildy wash and preparation method thereof |
| CN111358730A (en) * | 2020-03-17 | 2020-07-03 | 广东芭薇生物科技股份有限公司 | Double-layer cleansing lotion and preparation method thereof |
-
2020
- 2020-09-28 JP JP2020162247A patent/JP2022054953A/en active Pending
-
2021
- 2021-09-10 CN CN202180078362.0A patent/CN116490162A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107072898A (en) * | 2014-06-25 | 2017-08-18 | 莱雅公司 | Composition in the form of a nanoemulsion or microemulsion or with a layered structure |
| CN107997996A (en) * | 2017-12-12 | 2018-05-08 | 广州市仙婷贸易有限公司 | A kind of bilayer mildy wash and preparation method thereof |
| CN111358730A (en) * | 2020-03-17 | 2020-07-03 | 广东芭薇生物科技股份有限公司 | Double-layer cleansing lotion and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2022054953A (en) | 2022-04-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5554943B2 (en) | Transparent multilayer liquid cosmetics | |
| JP7258529B2 (en) | Composition containing two polyglycerol fatty acid esters | |
| JP7233896B2 (en) | Composition containing two polyglyceryl fatty acid esters | |
| JP5002434B2 (en) | Emulsifying bath composition | |
| FR3121041A1 (en) | Two-phase composition | |
| CN110022843B (en) | Non-adhesive stabilizing composition | |
| JP2024052982A (en) | Composition suitable for cleansing | |
| FR3045351A1 (en) | ||
| JP2017100985A (en) | Composition suitable for cosmetic use | |
| CN116490162A (en) | Two-phase composition | |
| FR3115456A1 (en) | TWO-PHASE COMPOSITION | |
| US20240156691A1 (en) | Two-phase composition | |
| CN117015365A (en) | two-phase composition | |
| WO2022065207A1 (en) | Two-phase composition | |
| CN116456955A (en) | Two-phase composition comprising at least one hydrocarbon oil and at least one citrate ester, wherein the composition is preferably a cleaning composition | |
| JP7423788B2 (en) | Composition for conditioning keratin fibers | |
| EP4216904A1 (en) | Two-phase composition comprising at least one hydrocarbon oil and at least one ester of citric acid, wherein the composition is preferably a cleansing composition | |
| JP2021084886A (en) | Stability composition | |
| JP2009091258A (en) | Foamy hair cosmetic |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |