CN116448479A - Automatic slicing device for general sampling of pathology biopsy - Google Patents
Automatic slicing device for general sampling of pathology biopsy Download PDFInfo
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- CN116448479A CN116448479A CN202310399984.4A CN202310399984A CN116448479A CN 116448479 A CN116448479 A CN 116448479A CN 202310399984 A CN202310399984 A CN 202310399984A CN 116448479 A CN116448479 A CN 116448479A
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- 238000001574 biopsy Methods 0.000 title claims abstract description 30
- 230000007170 pathology Effects 0.000 title abstract description 4
- 238000005070 sampling Methods 0.000 title abstract description 3
- 230000001575 pathological effect Effects 0.000 claims abstract description 67
- 238000004140 cleaning Methods 0.000 claims abstract description 37
- 230000007246 mechanism Effects 0.000 claims abstract description 12
- 239000000463 material Substances 0.000 claims abstract description 10
- 230000000149 penetrating effect Effects 0.000 claims abstract description 3
- 239000007788 liquid Substances 0.000 claims description 25
- 230000001681 protective effect Effects 0.000 claims description 18
- 239000002699 waste material Substances 0.000 claims description 16
- 238000007789 sealing Methods 0.000 claims description 11
- 238000002347 injection Methods 0.000 claims description 5
- 239000007924 injection Substances 0.000 claims description 5
- 238000004659 sterilization and disinfection Methods 0.000 abstract description 13
- 210000001503 joint Anatomy 0.000 abstract 1
- 238000000034 method Methods 0.000 description 14
- 230000008569 process Effects 0.000 description 11
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 10
- 230000000249 desinfective effect Effects 0.000 description 6
- 238000007790 scraping Methods 0.000 description 6
- 238000010586 diagram Methods 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 206010011409 Cross infection Diseases 0.000 description 3
- 206010029803 Nosocomial infection Diseases 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 3
- 238000003745 diagnosis Methods 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 239000006185 dispersion Substances 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 238000012544 monitoring process Methods 0.000 description 3
- 238000004544 sputter deposition Methods 0.000 description 3
- 238000003759 clinical diagnosis Methods 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 238000007689 inspection Methods 0.000 description 2
- 230000003902 lesion Effects 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 238000012864 cross contamination Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000012333 histopathological diagnosis Methods 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000010827 pathological analysis Methods 0.000 description 1
- 238000004393 prognosis Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
- B26D1/00—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor
- B26D1/01—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work
- B26D1/04—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work having a linearly-movable cutting member
- B26D1/06—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work having a linearly-movable cutting member wherein the cutting member reciprocates
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B1/00—Cleaning by methods involving the use of tools
- B08B1/10—Cleaning by methods involving the use of tools characterised by the type of cleaning tool
- B08B1/16—Rigid blades, e.g. scrapers; Flexible blades, e.g. wipers
- B08B1/165—Scrapers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B1/00—Cleaning by methods involving the use of tools
- B08B1/30—Cleaning by methods involving the use of tools by movement of cleaning members over a surface
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B3/00—Cleaning by methods involving the use or presence of liquid or steam
- B08B3/02—Cleaning by the force of jets or sprays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
- B26D7/00—Details of apparatus for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
- B26D7/27—Means for performing other operations combined with cutting
- B26D7/32—Means for performing other operations combined with cutting for conveying or stacking cut product
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
- G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
- G01N2001/2873—Cutting or cleaving
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P70/00—Climate change mitigation technologies in the production process for final industrial or consumer products
- Y02P70/10—Greenhouse gas [GHG] capture, material saving, heat recovery or other energy efficient measures, e.g. motor control, characterised by manufacturing processes, e.g. for rolling metal or metal working
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- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
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- Forests & Forestry (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
Description
技术领域technical field
本发明涉及医疗器械技术领域,特别涉及一种病理活检大体取材自动切片装置。The invention relates to the technical field of medical devices, in particular to an automatic slicing device for grossly taking pathological biopsy materials.
背景技术Background technique
活检是“活体组织检查”简称,亦称外科病理学检查,是指应诊断、治疗的需要,从患者体内切取、钳取或穿刺等取出病变组织,进行病理学检查的技术。它是诊断病理学中最重要的部分,对绝大多数送检病例都能做出明确的组织病理学诊断,被作为临床的最后诊断,活检能够协助临床对病变作出诊断或为疾病诊断提供线索;了解病变性质、发展趋势,判断疾病的预后;验证及观察药物疗效,为临床用药提供参考依据;参与临床科研,发现新的疾病或新的类型,为临床科研提供病理组织学依据。Biopsy is the abbreviation of "biological tissue examination", also known as surgical pathological examination, which refers to the technique of cutting, clamping or puncturing the diseased tissue from the patient's body for pathological examination in response to the needs of diagnosis and treatment. It is the most important part of diagnostic pathology. It can make a clear histopathological diagnosis for most of the cases submitted for inspection. It is used as the final clinical diagnosis. Biopsy can assist clinical diagnosis of lesions or provide clues for disease diagnosis. ; Understand the nature and development trend of lesions, and judge the prognosis of the disease; verify and observe the efficacy of drugs, and provide reference for clinical medication; participate in clinical research, discover new diseases or new types, and provide histopathological evidence for clinical research.
活检取材时,为便于后续的检验诊断,需要对从患者身上所取的病理组织进行切片处理,但是在现实操作过程中申请人发现,目前临床医学中,往往对病理组织采用人工切片处理的方式,人工切片处理方式普遍存在病理组织数量多、工作量大、操作误差大、容易扩散感染等问题,为此,本申请提供了一种病理活检大体取材自动切片装置来满足需求。When taking biopsy materials, in order to facilitate subsequent inspection and diagnosis, it is necessary to slice the pathological tissue taken from the patient, but in the actual operation process, the applicant found that in current clinical medicine, manual slice processing is often used for pathological tissue , the manual section processing generally has problems such as a large number of pathological tissues, a large workload, large operating errors, and easy spread of infection. Therefore, this application provides an automatic slicing device for pathological biopsy gross materials to meet the needs.
发明内容Contents of the invention
本发明要解决的技术问题是提供一种病理活检大体取材自动切片装置以解决现有技术下人工切片处理方式普遍存在病理组织数量多、工作量大、操作误差大、容易扩散感染的问题。The technical problem to be solved by the present invention is to provide an automatic slicing device for pathological biopsy gross materials to solve the common problems of large number of pathological tissues, heavy workload, large operation error and easy spread of infection in the manual slicing process in the prior art.
为解决上述技术问题,本发明提供如下技术方案:In order to solve the above technical problems, the present invention provides the following technical solutions:
一种病理活检大体取材自动切片装置,包括:An automatic slicing device for pathological biopsy gross materials, comprising:
机柜,机柜顶部开设有操作腔,操作腔内一侧设有用于活检切片的切片台以及切片机构,操作腔内另外一侧设有用于清洗的槽孔以及清洗板;所述切片台包括水平设置在操作腔内底壁上且能够移动的滑台,滑台上设置有圈座,圈座内部一端处开设有贯穿滑台的落料槽,圈座内部还设置有与滑台表面抵接且能够移动的刮板,机柜远离槽孔的一侧镶嵌有位于滑台下方的盛接盒。Cabinet, the top of the cabinet is provided with an operation chamber, one side of the operation chamber is provided with a slicing table and a slicing mechanism for biopsy slicing, and the other side of the operation chamber is provided with a slot for cleaning and a cleaning plate; the slicing table includes a horizontal setting On the bottom wall of the operation chamber and movable slide table, there is a ring seat on the slide table, and a blanking groove penetrating through the slide table is opened at one end inside the ring seat, and a ring seat is also provided inside the ring seat to abut against the surface of the slide table. The scraper can be moved, and the side of the cabinet away from the slot hole is inlaid with a splice box located under the slide table.
优选地,所述圈座外侧壁两端处均设有固定耳板,相对的两块固定耳板之间旋转连接有第一丝杆,第一丝杆上螺纹套设有活动耳板,活动耳板与刮板的端部连接,其中一块所述固定耳板上安装有能够驱动第一丝杆旋转的第一电机。Preferably, fixed ear plates are provided at both ends of the outer wall of the ring seat, and a first screw rod is rotatably connected between the two opposite fixed ear plates, and a movable ear plate is provided on a screw sleeve on the first screw rod. The lugs are connected to the ends of the scrapers, and one of the fixed lugs is equipped with a first motor capable of driving the first screw to rotate.
优选地,所述滑台下表面设置有能够对盛接盒顶部密封的密封垫。Preferably, the lower surface of the slide table is provided with a sealing gasket capable of sealing the top of the receiving box.
优选地,所述滑台朝向槽孔一端的两侧均设有凸板,凸板底部设有凸块,所述操作腔底壁上开设有供凸块滑动的密封垫。Preferably, both sides of the slide table facing the slot hole are provided with convex plates, the bottom of the convex plate is provided with a protrusion, and the bottom wall of the operation chamber is provided with a sealing gasket for the protrusion to slide.
优选地,所述密封垫内旋转安装有第二丝杆,第二丝杆螺纹贯穿凸块,所述机柜的外侧壁上安装有能够驱动第二丝杆旋转的第二电机。Preferably, a second screw rod is rotatably installed inside the sealing pad, and the second screw rod threads through the protrusion, and a second motor capable of driving the second screw rod to rotate is installed on the outer wall of the cabinet.
优选地,所述槽孔内可拆卸安装有滤网,机柜上设有位于槽孔下方的废料盒,废料盒的下方设置有清洗盒,清洗盒内设有设有能够朝向废料盒输送液体的输送泵。Preferably, a filter screen is detachably installed in the slot, a waste box located below the slot is provided on the cabinet, a cleaning box is provided below the waste box, and a cleaning box is provided in the cleaning box to transport liquid toward the waste box. Pump.
优选地,所述机柜位于盛接盒下方的位置处开设有储存腔,储存腔内设有储液罐,操作腔内底壁上安装有与储液罐连通的注液阀。Preferably, the cabinet is provided with a storage chamber at a position below the receiving box, a liquid storage tank is provided in the storage chamber, and a liquid injection valve communicating with the liquid storage tank is installed on the bottom wall of the operation chamber.
优选地,所述机柜的正面设有控制面板,所述操作腔的两侧设有侧板,操作腔的正面设有能够卷收的软板,所述侧板和软板均呈透明状。Preferably, a control panel is provided on the front of the cabinet, side panels are provided on both sides of the operation chamber, and a flexible board that can be rolled is provided on the front of the operation chamber, and the side boards and the soft board are transparent.
优选地,所述切片机构包括安装在机柜顶部的电动推杆、安装在电动推杆伸缩端的安装板以及安装在安装板底部的切刀,电动推杆与盛接盒竖向对应,电动推杆的伸缩端贯穿机柜顶部伸入操作腔内,所述切刀等间距设有多片。Preferably, the slicing mechanism includes an electric push rod installed on the top of the cabinet, a mounting plate mounted on the telescopic end of the electric push rod, and a cutter mounted on the bottom of the mounting plate, the electric push rod is vertically corresponding to the receiving box, and the electric push rod The telescopic end of the utility model extends through the top of the cabinet and extends into the operating cavity, and the cutters are provided with multiple pieces at equal intervals.
优选地,所述安装板底部设有护框,护框能够容安装板底部的所有切刀嵌入,所述护框外壁上设有托片,托片上竖直固定有支杆,安装板侧壁竖直设有供支杆插入的套筒,支杆顶端与套筒内部顶壁之间设有弹簧。Preferably, a protective frame is provided at the bottom of the mounting plate, and the protective frame can accommodate all the cutters at the bottom of the mounting plate to be embedded, and a supporting piece is provided on the outer wall of the protective frame, and a pole is vertically fixed on the supporting piece, and the side wall of the mounting plate A sleeve for inserting the pole is arranged vertically, and a spring is arranged between the top end of the pole and the inner top wall of the sleeve.
本发明与现有技术相比,至少具有如下有益效果:Compared with the prior art, the present invention has at least the following beneficial effects:
上述方案中,通过切片机构的设置,病理组织切片时,滑台位于盛接盒上方位置处,只需将患者身上去切取的病理组织放置在圈座内的滑台上,然后启动电动推杆推动安装板下压,护框能够率先将圈套限位,然后由多片切刀逐渐嵌入护框内,完成对病理组织的切片,利用护框对病理组织的率先圈套限位,能够使多片切刀单次快速完成病理组织的切片,既方便快捷,又可避免病理组织溅射,减少病理组织的扩散,增强其使用效果。In the above scheme, through the setting of the slicing mechanism, when the pathological tissue is sliced, the sliding table is located above the receiving box, and only the pathological tissue to be cut from the patient is placed on the sliding table in the ring seat, and then the electric push rod is activated Push the mounting plate down, the protective frame can take the lead in limiting the trap, and then gradually insert the multi-slice cutter into the protective frame to complete the sectioning of the pathological tissue. Using the protective frame to first trap the pathological tissue can make the multi-slice The cutter quickly completes the slicing of the pathological tissue at a single time, which is convenient and quick, and can avoid the sputtering of the pathological tissue, reduce the spread of the pathological tissue, and enhance its use effect.
通过圈座内设置的刮板,在病理组织切片完成后,启动第一电机带动第一丝杆旋转,利用活动耳板带动刮板由圈座内远离落料槽的一端朝向落料槽移动,可将滑台上切片的病理组织从落料槽处排向盛接盒内,盛接盒内只需预先准备福尔马林,切片的病理组织落入盛接盒内后,将盛接盒抽出机柜即可用于活检,实现对切片病理组织的收取,且整个切片病理组织收取过程方便快捷,配合圈座的围绕,可避免切片病理组织的分散,自动化程度较高,有利于临床应用。Through the scraper set in the ring seat, after the pathological tissue sectioning is completed, start the first motor to drive the first screw rod to rotate, and use the movable ear plate to drive the scraper to move from the end of the ring seat away from the blanking chute towards the blanking trough, The pathological tissue sliced on the sliding table can be discharged from the blanking chute into the receiving box. Only formalin needs to be prepared in the receiving box. After the sliced pathological tissue falls into the receiving box, the receiving box Pulling out the cabinet can be used for biopsy to realize the collection of sliced pathological tissues, and the whole collection process of sliced pathological tissues is convenient and fast. With the surrounding of the ring seat, it can avoid the dispersion of sliced pathological tissues. The degree of automation is high, which is beneficial to clinical application.
通过清洗板和槽孔的设置,在病理组织切片、收取完成后,利用第二丝杆与凸块的配合,带动滑台朝向槽孔平移,当滑台平移至槽孔上方时,清洗盒内的清洗消毒液由清洗板喷出,清洗消毒液喷洒在圈座内的滑台上,同时启动第一电机驱动刮板沿滑台上表面来回移动,即可实现对滑台上表面用于病理组织切片部分的刮洗消毒,且刮洗消毒后的废液由落料槽排入槽孔,利用滤网过滤后排入废料盒内收集,通过清洗消毒,可避免后续切片过程中交叉感染,增强该装置的自动化使用性能。Through the setting of the cleaning plate and the slot hole, after the pathological tissue sectioning and collection are completed, the cooperation between the second screw rod and the protrusion is used to drive the sliding table to move toward the slot hole. When the sliding table moves to the top of the slot hole, the cleaning box The cleaning and disinfecting liquid is sprayed from the cleaning plate, and the cleaning and disinfecting liquid is sprayed on the sliding table in the ring seat, and at the same time, the first motor is started to drive the scraper to move back and forth along the upper surface of the sliding table, so that the upper surface of the sliding table can be used for pathology. Scraping and disinfection of the tissue section, and the waste liquid after scraping and disinfection is discharged from the blanking trough into the slot hole, filtered by the filter and then discharged into the waste box for collection. Through cleaning and disinfection, cross-infection in the subsequent slicing process can be avoided. Enhance the automation performance of the device.
通过侧板和软板的设置,在自动切片、自动取片、自动清洗消毒过程中,透明状的侧板和软板既能够进行遮挡防护,又便于操作人员监视,满足使用需求,增强该装置的使用性能。Through the setting of side panels and soft panels, the transparent side panels and soft panels can not only provide shielding protection, but also facilitate operator monitoring during the process of automatic slicing, automatic slice taking, and automatic cleaning and disinfection, which meets the needs of use and enhances the device performance.
附图说明Description of drawings
并入本文中并且构成说明书的部分的附图示出了本公开的实施例,并且与说明书一起进一步用来对本公开的原理进行解释,并且使相关领域技术人员能够实施和使用本公开。The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments of the disclosure and, together with the description, serve to further explain the principles of the disclosure and to enable those skilled in the relevant art to make and use the disclosure.
图1为病理活检大体取材自动切片装置整体结构示意图;1 is a schematic diagram of the overall structure of an automatic slicing device for general biopsy sampling;
图2为病理活检大体取材自动切片装置的操作腔结构示意图;Fig. 2 is a schematic diagram of the structure of the operating chamber of the automatic slicing device for the general collection of pathological biopsy materials;
图3为切片台的结构示意图;Fig. 3 is the structural representation of slicing platform;
图4为图2中的A处放大结构示意图;Fig. 4 is a schematic diagram of an enlarged structure at A in Fig. 2;
图5为盛接盒的结构示意图;Fig. 5 is a structural schematic diagram of the splicing box;
图6为切片机构的结构示意图;Fig. 6 is the structural representation of slicing mechanism;
图7为切片机构的分解图。Fig. 7 is an exploded view of the slicing mechanism.
[附图标记][reference sign]
1、机柜;2、侧板;3、软板;4、储存腔;5、储液罐;6、盛接盒;7、废料盒;8、清洗盒;9、控制面板;10、操作腔;11、切片台;12、切片机构;13、注液阀;14、槽孔;15、滤网;16、第二电机;17、清洗板;18、滑台;19、圈座;20、落料槽;21、刮板;22、固定耳板;23、第一丝杆;24、第一电机;25、活动耳板;26、凸板;27、凸块;28、密封垫;29、第二丝杆;30、弧形凸起;31、内盒;32、电动推杆;33、安装板;34、切刀;35、护框;36、套筒;37、托片;38、支杆;39、弹簧。1. Cabinet; 2. Side panel; 3. Soft board; 4. Storage chamber; 5. Liquid storage tank; 6. Receiving box; 7. Waste box; 8. Cleaning box; 9. Control panel; 10. Operation chamber ;11, slicing table; 12, slicing mechanism; 13, liquid injection valve; 14, slot hole; 15, filter screen; 16, second motor; 17, cleaning plate; Blanking trough; 21, scraper; 22, fixed ear plate; 23, first screw rod; 24, first motor; 25, movable ear plate; 26, convex plate; 27, bump; 28, sealing gasket; 29 , second screw rod; 30, arc-shaped protrusion; 31, inner box; 32, electric push rod; 33, mounting plate; 34, cutter; 35, protective frame; 36, sleeve; 37, support piece; 38 , pole; 39, spring.
如图所示,为了能明确实现本发明的实施例的结构,在图中标注了特定的结构和器件,但这仅为示意需要,并非意图将本发明限定在该特定结构、器件和环境中,根据具体需要,本领域的普通技术人员可以将这些器件和环境进行调整或者修改,所进行的调整或者修改仍然包括在后附的权利要求的范围中。As shown in the figure, in order to clearly realize the structure of the embodiment of the present invention, specific structures and devices are marked in the figures, but this is only for illustrative purposes, and is not intended to limit the present invention to the specific structures, devices and environments According to specific needs, those skilled in the art can adjust or modify these devices and environments, and the adjustments or modifications are still included in the scope of the appended claims.
具体实施方式Detailed ways
下面结合附图和具体实施例对本发明提供的一种病理活检大体取材自动切片装置进行详细描述。同时在这里做以说明的是,为了使实施例更加详尽,下面的实施例为最佳、优选实施例,对于一些公知技术本领域技术人员也可采用其他替代方式而进行实施;而且附图部分仅是为了更具体的描述实施例,而并不旨在对本发明进行具体的限定。An automatic slicing device for pathological biopsy gross material collection provided by the present invention will be described in detail below with reference to the accompanying drawings and specific embodiments. At the same time, it is explained here that in order to make the embodiments more detailed, the following embodiments are the best and preferred embodiments, and those skilled in the art can also adopt other alternative ways to implement for some known technologies; and the accompanying drawings It is only for more specific description of the embodiments, but not intended to specifically limit the present invention.
需要指出的是,在说明书中提到“一个实施例”、“实施例”、“示例性实施例”、“一些实施例”等指示所述的实施例可以包括特定特征、结构或特性,但未必每个实施例都包括该特定特征、结构或特性。另外,在结合实施例描述特定特征、结构或特性时,结合其它实施例(无论是否明确描述)实现这种特征、结构或特性应在相关领域技术人员的知识范围内。It should be noted that references in the specification to "one embodiment," "an embodiment," "exemplary embodiment," "some embodiments," etc. indicate that the described embodiments may include particular features, structures, or characteristics, but Not every embodiment includes that particular feature, structure or characteristic. In addition, when a particular feature, structure or characteristic is described in connection with an embodiment, it should be within the knowledge of those skilled in the relevant art to implement such feature, structure or characteristic in combination with other embodiments (whether or not explicitly described).
通常,可以至少部分从上下文中的使用来理解术语。例如,至少部分取决于上下文,本文中使用的术语“一个或多个”可以用于描述单数意义的任何特征、结构或特性,或者可以用于描述复数意义的特征、结构或特性的组合。另外,术语“基于”可以被理解为不一定旨在传达一组排他性的因素,而是可以替代地,至少部分地取决于上下文,允许存在不一定明确描述的其他因素。In general, a term can be understood at least in part from its usage in context. For example, the term "one or more" as used herein may be used to describe any feature, structure or characteristic in the singular or may be used to describe a combination of features, structures or characteristics in the plural, depending at least in part on the context. Additionally, the term "based on" may be understood as not necessarily intended to convey an exclusive set of factors, but may instead allow for the presence of other factors not necessarily expressly described, depending at least in part on the context.
可以理解的是,本公开中的“在……上”、“在……之上”和“在……上方”的含义应当以最宽方式被解读,以使得“在……上”不仅表示“直接在”某物“上”而且还包括在某物“上”且其间有居间特征或层的含义,并且“在……之上”或“在……上方”不仅表示“在”某物“之上”或“上方”的含义,而且还可以包括其“在”某物“之上”或“上方”且其间没有居间特征或层的含义。It will be appreciated that the meanings of "on", "over" and "above" in this disclosure should be read in the broadest possible manner such that "on" means not only "Directly on" something also includes the meaning of "on" something with an intervening feature or layer in between, and "on" or "over" not only means "on" something The meaning of "on" or "over" and may also include its meaning of "on" or "over" something without intervening features or layers in between.
此外,诸如“在…之下”、“在…下方”、“下部”、“在…之上”、“上部”等空间相关术语在本文中为了描述方便可以用于描述一个元件或特征与另一个或多个元件或特征的关系,如在附图中示出的。空间相关术语旨在涵盖除了在附图所描绘的取向之外的在设备使用或操作中的不同取向。设备可以以另外的方式被定向,并且本文中使用的空间相关描述词可以类似地被相应解释。In addition, spatial relative terms such as "under", "beneath", "lower", "above", "upper", etc. may be used herein for convenience of description to describe the relationship between one element or feature and another. The relationship of one or more elements or features as shown in the drawings. Spatially relative terms are intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the figures. A device may be otherwise oriented and spatially relative descriptors used herein similarly interpreted accordingly.
如图1、图2、图3、图6和图7所示,本发明的实施例提供一种病理活检大体取材自动切片装置,包括:机柜1,机柜1顶部开设有操作腔10,操作腔10内一侧设有用于活检切片的切片台11以及切片机构12,操作腔10内另外一侧设有用于清洗的槽孔14以及清洗板17;切片台11包括水平设置在操作腔10内底壁上且能够移动的滑台18,滑台18上设置有圈座19,圈座19内部一端处开设有贯穿滑台18的落料槽20,圈座19内部还设置有与滑台18表面抵接且能够移动的刮板21,机柜1远离槽孔14的一侧镶嵌有位于滑台18下方的盛接盒6。As shown in Fig. 1, Fig. 2, Fig. 3, Fig. 6 and Fig. 7, the embodiment of the present invention provides a kind of automatic slicing device for pathological biopsy generally taking materials, comprising: a cabinet 1, an operating chamber 10 is opened on the top of the cabinet 1, the operating chamber One side of the 10 is provided with a slicing table 11 and a slicing mechanism 12 for biopsy slicing, and the other side of the operating chamber 10 is provided with a slot 14 for cleaning and a cleaning plate 17; On the wall and movable slide table 18, the slide table 18 is provided with a ring seat 19, and one end inside the ring seat 19 is provided with a blanking groove 20 that runs through the slide table 18, and the inside of the ring seat 19 is also provided with a The contacting and movable scraper 21 , the side of the cabinet 1 away from the slot hole 14 is inlaid with the receiving box 6 located under the slide table 18 .
进一步的,切片机构12包括安装在机柜1顶部的电动推杆32、安装在电动推杆32伸缩端的安装板33以及安装在安装板33底部的切刀34,电动推杆32与盛接盒6竖向对应,电动推杆32的伸缩端贯穿机柜1顶部伸入操作腔10内,切刀34等间距设有多片,安装板33底部设有护框35,护框35能够容安装板33底部的所有切刀34嵌入,护框35外壁上设有托片37,托片37上竖直固定有支杆38,安装板33侧壁竖直设有供支杆38插入的套筒36,支杆38顶端与套筒36内部顶壁之间设有弹簧39。Further, the slicing mechanism 12 includes an electric push rod 32 mounted on the top of the cabinet 1, a mounting plate 33 mounted on the telescopic end of the electric push rod 32, and a cutter 34 mounted on the bottom of the mounting plate 33, the electric push rod 32 and the receiving box 6 Corresponding vertically, the telescopic end of the electric push rod 32 penetrates the top of the cabinet 1 and extends into the operating chamber 10, the cutter 34 is provided with multiple pieces at equal intervals, and the bottom of the mounting plate 33 is provided with a protective frame 35, which can accommodate the mounting plate 33 All the cutters 34 at the bottom are embedded, and the outer wall of the protective frame 35 is provided with a supporting piece 37, the supporting piece 37 is vertically fixed with a pole 38, and the side wall of the mounting plate 33 is vertically provided with a sleeve 36 for the insertion of the pole 38, A spring 39 is provided between the top of the pole 38 and the inner top wall of the sleeve 36 .
通过上述技术方案,病理组织切片时,只需将患者身上去切取的病理组织放置在圈座19内的滑台18上,然后启动电动推杆32推动安装板33下压,护框35能够率先将圈套限位,然后由多片切刀34逐渐嵌入护框35内,完成对病理组织的切片,利用护框35对病理组织的率先圈套限位,能够使多片切刀34单次快速完成病理组织的切片,既方便快捷,又可避免病理组织溅射,减少病理组织的扩散,增强其使用效果。Through the above technical solution, when slicing pathological tissue, it is only necessary to place the pathological tissue cut from the patient on the slide table 18 in the ring seat 19, and then start the electric push rod 32 to push the mounting plate 33 down, and the protective frame 35 can take the lead. The snare is limited, and then the multi-slice cutter 34 is gradually embedded in the protective frame 35 to complete the sectioning of the pathological tissue. Using the protective frame 35 to first trap the pathological tissue to limit the position, the multi-slice cutter 34 can be quickly completed in a single time. The slicing of pathological tissue is convenient and fast, and can avoid the sputtering of pathological tissue, reduce the spread of pathological tissue, and enhance its use effect.
如图2、图3、图5,在本实施例中,圈座19外侧壁两端处均设有固定耳板22,相对的两块固定耳板22之间旋转连接有第一丝杆23,第一丝杆23上螺纹套设有活动耳板25,活动耳板25与刮板21的端部连接,其中一块固定耳板22上安装有能够驱动第一丝杆23旋转的第一电机24。在病理组织切片完成后,启动第一电机24带动第一丝杆23旋转,利用活动耳板25带动刮板21由圈座19内远离落料槽20的一端朝向落料槽20移动,可将滑台18上切片的病理组织从落料槽20处排向盛接盒6内,盛接盒6内只需预先准备福尔马林,切片的病理组织落入盛接盒6内后,将盛接盒6抽出机柜1即可用于活检,实现对切片病理组织的收取,且整个切片病理组织收取过程方便快捷,配合圈座19的围绕,可避免切片病理组织的分散,自动化程度较高,有利于临床应用。As shown in Fig. 2, Fig. 3 and Fig. 5, in this embodiment, fixed lugs 22 are provided at both ends of the outer wall of the ring seat 19, and a first screw rod 23 is rotatably connected between the two opposite fixed lugs 22. , the first threaded mandrel 23 is provided with a movable ear plate 25, the movable ear plate 25 is connected to the end of the scraper 21, and one of the fixed ear plates 22 is equipped with a first motor capable of driving the first screw mandrel 23 to rotate twenty four. After the pathological tissue slicing is completed, start the first motor 24 to drive the first screw mandrel 23 to rotate, and use the movable ear plate 25 to drive the scraper 21 to move toward the blanking trough 20 from the end far away from the blanking trough 20 in the circle seat 19, so that the The pathological tissues sliced on the sliding table 18 are discharged from the blanking chute 20 into the receiving box 6, and only formalin needs to be prepared in the receiving box 6, and after the pathological tissues of the slices fall into the receiving box 6, the The receiving box 6 can be used for biopsy after being drawn out of the cabinet 1 to realize the collection of sliced pathological tissues, and the whole collection process of sliced pathological tissues is convenient and fast. With the surrounding of the ring seat 19, the dispersion of sliced pathological tissues can be avoided, and the degree of automation is high. conducive to clinical application.
进一步的,机柜1位于盛接盒6下方的位置处开设有储存腔4,储存腔4内设有储液罐5,操作腔10内底壁上安装有与储液罐5连通的注液阀13,储液罐5内用于存储福尔马林,注液阀13能够将储液罐5内的福尔马林抽送至盛接盒6内。其中盛接盒6内设有内盒31,内盒31设为一次性,可避免交叉污染,盛接盒6的两侧设有弧形凸起30,用于对盛接盒6限位导向。滑台18下表面设置有能够对盛接盒6顶部密封的密封垫28。Further, the cabinet 1 is provided with a storage chamber 4 at a position below the receiving box 6, a liquid storage tank 5 is provided in the storage chamber 4, and a liquid injection valve communicating with the liquid storage tank 5 is installed on the inner bottom wall of the operation chamber 10 13 , the liquid storage tank 5 is used to store formalin, and the liquid injection valve 13 can pump the formalin in the liquid storage tank 5 into the receiving box 6 . Wherein the receiving box 6 is provided with an inner box 31, and the inner box 31 is set as disposable, which can avoid cross-contamination, and both sides of the receiving box 6 are provided with arc-shaped protrusions 30, which are used to limit and guide the receiving box 6 . The lower surface of the slide table 18 is provided with a gasket 28 capable of sealing the top of the receiving box 6 .
如图1、图2-图4所示,在本实施例中,滑台18朝向槽孔14一端的两侧均设有凸板26,凸板26底部设有凸块27,操作腔10底壁上开设有供凸块27滑动的密封垫28。密封垫28内旋转安装有第二丝杆29,第二丝杆29螺纹贯穿凸块27,机柜1的外侧壁上安装有能够驱动第二丝杆29旋转的第二电机16,槽孔14内可拆卸安装有滤网15,机柜1上设有位于槽孔14下方的废料盒7,废料盒7的下方设置有清洗盒8,清洗盒8内设有设有能够朝向废料盒7输送液体的输送泵。As shown in Fig. 1, Fig. 2-Fig. 4, in this embodiment, both sides of the slide table 18 towards the end of the slot hole 14 are provided with a convex plate 26, the bottom of the convex plate 26 is provided with a bump 27, and the bottom of the operating chamber 10 A sealing gasket 28 for sliding of the protrusion 27 is provided on the wall. A second screw mandrel 29 is rotatably installed in the gasket 28, and the thread of the second screw mandrel 29 runs through the protrusion 27. A second motor 16 capable of driving the second screw mandrel 29 to rotate is installed on the outer wall of the cabinet 1. A filter screen 15 is detachably installed, and the cabinet 1 is provided with a waste box 7 positioned at the bottom of the slot 14. A cleaning box 8 is provided below the waste box 7, and the cleaning box 8 is provided with a liquid that can transport liquid towards the waste box 7. Pump.
通过上述技术方案,在病理组织切片、收取完成后,利用第二丝杆29与凸块27的配合,带动滑台18朝向槽孔14平移,当滑台18平移至槽孔14上方时,清洗盒8内的清洗消毒液由清洗板17喷出,清洗消毒液喷洒在圈座19内的滑台18上,同时启动第一电机24驱动刮板21沿滑台18上表面来回移动,即可实现对滑台18上表面用于病理组织切片部分的刮洗消毒,且刮洗消毒后的废液由落料槽20排入槽孔14,利用滤网15过滤后排入废料盒7内收集,通过清洗消毒,可避免后续切片过程中交叉感染,增强该装置的自动化使用性能。Through the above technical scheme, after the pathological tissue sectioning and collection are completed, the cooperation between the second screw rod 29 and the bump 27 is used to drive the slide table 18 to translate towards the slot hole 14. When the slide table 18 translates to the top of the slot hole 14, cleaning The cleaning and disinfecting solution in the box 8 is sprayed by the cleaning plate 17, and the cleaning and disinfecting solution is sprayed on the slide table 18 in the ring seat 19, and at the same time, the first motor 24 is started to drive the scraper 21 to move back and forth along the upper surface of the slide table 18. Realize the scraping and disinfection of the upper surface of the slide table 18 for the pathological tissue section, and the waste liquid after scraping and disinfection is discharged into the slot hole 14 from the blanking trough 20, filtered by the filter screen 15, and then discharged into the waste box 7 for collection , through cleaning and disinfection, cross-infection in the subsequent slicing process can be avoided, and the automatic performance of the device can be enhanced.
进一步的,机柜1的正面设有控制面板9,操作腔10的两侧设有侧板2,操作腔10的正面设有能够卷收的软板3,侧板2和软板3均呈透明状,在自动切片、自动取片、自动清洗消毒过程中,透明状的侧板2和软板3既能够进行遮挡防护,又便于操作人员监视,满足使用需求,增强该装置的使用性能。Further, a control panel 9 is provided on the front of the cabinet 1, side panels 2 are provided on both sides of the operation chamber 10, and a soft board 3 that can be retracted is provided on the front of the operation chamber 10, and the side board 2 and the soft board 3 are transparent. In the process of automatic slicing, automatic slice taking, and automatic cleaning and disinfection, the transparent side plate 2 and soft plate 3 can not only provide shielding and protection, but also facilitate operator monitoring, meet the needs of use, and enhance the performance of the device.
本发明提供的技术方案,The technical scheme provided by the present invention,
通过切片机构的设置,病理组织切片时,滑台位于盛接盒上方位置处,只需将患者身上去切取的病理组织放置在圈座内的滑台上,然后启动电动推杆推动安装板下压,护框能够率先将圈套限位,然后由多片切刀逐渐嵌入护框内,完成对病理组织的切片,利用护框对病理组织的率先圈套限位,能够使多片切刀单次快速完成病理组织的切片,既方便快捷,又可避免病理组织溅射,减少病理组织的扩散,增强其使用效果。Through the setting of the slicing mechanism, when the pathological tissue is sliced, the sliding table is located above the receiving box, and only the pathological tissue to be cut from the patient is placed on the sliding table in the ring seat, and then the electric push rod is activated to push the mounting plate down Press, the protective frame can take the lead in limiting the trap, and then gradually insert the multi-slice cutter into the protective frame to complete the sectioning of the pathological tissue. Using the protective frame to first trap the pathological tissue can make the multi-slice cutter single-shot Quickly complete the sectioning of pathological tissue, which is convenient and fast, and can avoid sputtering of pathological tissue, reduce the spread of pathological tissue, and enhance its use effect.
通过圈座内设置的刮板,在病理组织切片完成后,启动第一电机带动第一丝杆旋转,利用活动耳板带动刮板由圈座内远离落料槽的一端朝向落料槽移动,可将滑台上切片的病理组织从落料槽处排向盛接盒内,盛接盒内只需预先准备福尔马林,切片的病理组织落入盛接盒内后,将盛接盒抽出机柜即可用于活检,实现对切片病理组织的收取,且整个切片病理组织收取过程方便快捷,配合圈座的围绕,可避免切片病理组织的分散,自动化程度较高,有利于临床应用。Through the scraper set in the ring seat, after the pathological tissue sectioning is completed, start the first motor to drive the first screw rod to rotate, and use the movable ear plate to drive the scraper to move from the end of the ring seat away from the blanking chute towards the blanking trough, The pathological tissue sliced on the sliding table can be discharged from the blanking chute into the receiving box. Only formalin needs to be prepared in the receiving box. After the sliced pathological tissue falls into the receiving box, the receiving box Pulling out the cabinet can be used for biopsy to realize the collection of sliced pathological tissues, and the whole collection process of sliced pathological tissues is convenient and fast. With the surrounding of the ring seat, it can avoid the dispersion of sliced pathological tissues. The degree of automation is high, which is beneficial to clinical application.
通过清洗板和槽孔的设置,在病理组织切片、收取完成后,利用第二丝杆与凸块的配合,带动滑台朝向槽孔平移,当滑台平移至槽孔上方时,清洗盒内的清洗消毒液由清洗板喷出,清洗消毒液喷洒在圈座内的滑台上,同时启动第一电机驱动刮板沿滑台上表面来回移动,即可实现对滑台上表面用于病理组织切片部分的刮洗消毒,且刮洗消毒后的废液由落料槽排入槽孔,利用滤网过滤后排入废料盒内收集,通过清洗消毒,可避免后续切片过程中交叉感染,增强该装置的自动化使用性能。Through the setting of the cleaning plate and the slot hole, after the pathological tissue sectioning and collection are completed, the cooperation between the second screw rod and the protrusion is used to drive the sliding table to move toward the slot hole. When the sliding table moves to the top of the slot hole, the cleaning box The cleaning and disinfecting liquid is sprayed from the cleaning plate, and the cleaning and disinfecting liquid is sprayed on the sliding table in the ring seat, and at the same time, the first motor is started to drive the scraper to move back and forth along the upper surface of the sliding table, so that the upper surface of the sliding table can be used for pathology. Scraping and disinfection of the tissue section, and the waste liquid after scraping and disinfection is discharged from the blanking trough into the slot hole, filtered by the filter and then discharged into the waste box for collection. Through cleaning and disinfection, cross-infection in the subsequent slicing process can be avoided. Enhance the automation performance of the device.
通过侧板和软板的设置,在自动切片、自动取片、自动清洗消毒过程中,透明状的侧板和软板既能够进行遮挡防护,又便于操作人员监视,满足使用需求,增强该装置的使用性能。Through the setting of side panels and soft panels, the transparent side panels and soft panels can not only provide shielding protection, but also facilitate operator monitoring during the process of automatic slicing, automatic slice taking, and automatic cleaning and disinfection, which meets the needs of use and enhances the device performance.
本领域普通技术人员可以理解实现上述实施例方法中的全部或部分步骤是可以通过程序来指令相关的硬件来完成,该程序可以存储于计算机可读取存储介质中,如:ROM/RAM、磁碟、光盘等。Those of ordinary skill in the art can understand that all or part of the steps in the method of the above-mentioned embodiments can be completed by instructing related hardware through a program, and the program can be stored in a computer-readable storage medium, such as: ROM/RAM, magnetic disk, etc. Discs, discs, etc.
以上所述仅是本发明的优选实施方式,应当指出,对于本技术领域的普通技术人员来说,在不脱离本发明原理的前提下,还可以作出若干改进和润饰,这些改进和润饰也应视为本发明的保护范围。The above is only a preferred embodiment of the present invention, it should be pointed out that for those of ordinary skill in the art, without departing from the principle of the present invention, some improvements and modifications can also be made, and these improvements and modifications should also be It is regarded as the protection scope of the present invention.
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