CN1164401A

CN1164401A - Shuweiping-drug for curing gastropathy

Info

Publication number: CN1164401A
Application number: CN96107725A
Authority: CN
Inventors: 杨和华
Original assignee: Individual
Current assignee: Individual
Priority date: 1996-06-13
Filing date: 1996-06-13
Publication date: 1997-11-12
Anticipated expiration: 2016-06-13
Also published as: CN1076609C

Abstract

The present invention relates to a Chinese patent medicine for curing chronic gastritis, atrophic gastritis and duodenal bulbar ulcer-Shuweiping. Said medicine possesses the functions of upraising mechanism of qi, arousing spleen and warming stomach, clearing heat and nourishing yin, soothing liver and relieving stomach, and activating channel and transforming stasis, etc., and has the actions of improving enterogastric digestive function, absorption capacity and moving function, improving human body self-nutrition and promoting restoration and regeneration of gastric mucosa, so that it has the good therapeutic effect for stomachalgia, hyperhydrochloria, hypohydrochloria and stomach distention, etc.. Its effective rate is 98%, and its preparation is simple and cost is low.

Description

Shuweiping-drug for curing gastropathy

The present invention relates to a kind of Chinese patent medicine of curing chronic gastritis, atrophic gastritis and duodenal bulbar ulcer.

According to existing data, known gastropathy medication " XIANGSHA YANGWEI WAN ", " XIANGSHA LIUJU WAN ", " KUAIWEI PIAN ", " YANGWEISHU ", " WENWEISHU ", " SANJIU WEITAI ", " money is given birth to ball ", " guarantor closes ball " and " spleen-strengthening bolus " etc., be all individual event treatment or clothes with xerostomia, the edema phenomenon." lenitive pill ", " spleen-strengthening bolus ", " money give birth to ball " are not relaxed to temporary dyspepsia, anorexia, vomiting and stomach the effect of alleviation, but the gastritis unsatisfactory curative effect that stomachache, gastric acid, flatulence are caused; " XIANGSHA YANGWEI WAN ", " XIANGSHA LIUJU WAN " all are the diseases of treatment weakness of the spleen and stomach, hyperactive liver-QI attacking the stomach though prescription has difference, and be little to deficiency of stomach-Yin, the effect of cold-evil visitor stomach; " YANGWEISHU ", " WENWEISHU " are though there is the effect of strengthening the body resistance, tonifying-Yin and nourishing-stomach, but can not be close on the gastric and duodenal ulcers face, form protecting film and promote mucosa regeneration, can not adjust too much gastric acid, not normal stool and improper digestion and food-intake; " KUAIWEI PIAN " though the effect of antiinflammatory, granulation promoting, antacid, pain relieving is arranged, to stomach Anhui feeling of fullness expand painful or swollen distension, dim gas curative effect without cease very poor.

This and bright easypro stomach spirit with the diabetes involving middle-JIAO painful abdominal mass, the pond pyrolysis of stomach warming sending down the abnormal ascending QI is dry, purging FU-organs swing and, sending down the abnormal ascending QI looses strongly fragrantly, the yin nourishing QI invigorating is a purpose.With the Radix Astragali, the pleasant phagocytic function of Radix Aucklandiae QI invigorating, increase the ability of pathogenic microorganism inducement interferon, enhancing human body immunity power with the enhancing reticuloendothelial system; With Fructus Amomi, Rhizoma Atractylodis, thickly pounce on, on the Rhizoma Corydalis cold expelling pain, dyspepsia and intestinal stasis relieving with Radix Salviae Miltiorrhizae, the Rhizoma Chuanxiong blood circulation promoting and blood stasis dispelling; With Fructus Aurantii Immaturus, Radix Curcumae depressed liver-energy dispersing and QI regulating stomach function regulating, with the corruption of Os Sepiae convergence antacid; All share approximately then taste must with, irritability must be relaxed, deficiency-heat gets clearly, the gastral cavity painful abdominal mass must disappear, heating installation must be suitable.

The present invention has had the function of relieving distension, pain relieving antacid, granulation promoting, convergence from clinical confirmation, especially to pain on the cold-evil visitor stomach energy cold expelling, retention of food and drink energy dyspepsia and intestinal stasis relieving, hyperactive liver-QI attacking the stomach energy depressed liver-energy dispersing and QI regulating, the hot stomach function regulating in the syndrome of liver-stomach heat soothing the liver pond of energy, stomach-Yin loss energy yin nourishing stomach reinforcing, Deficiency and coldness of spleen and stomach can warming middle-JIAO and strengthening the spleen.

Modern medicine thinks that the effect that above-mentioned three kinds of digestive tract pathological changes are the long-term factors under attack of gastric mucosa causes gastric mucosal barrier and gastric mucus screen to fall destructive result.Normal gastric mucosal blood flow is the basis of keeping normal stool, absorption, secretion and excretory function, and chronic gastritis, atrophic gastritis and three kinds of diseases of duodenal bulbar ulcer all exist viscosity of blood to increase, blood flow rate slows down, erythrocyte aggregation increases and hemorheology sexual disorders such as blood viscosity increase.Through clinical the taking of patients such as stomachache, gastric acid, flatulence thousand examples, the blood test situation is as follows before and after the treatment as the spirit of Yi Benshu stomach:

Hemorheology index changes (mean value standard error)

Project	Before the treatment	After the treatment	The P value
Project	Before the treatment	After the treatment	The P value	The high shear of whole blood contrast viscosity	Man: 4.78 ± 1.71 woman: 4.65 ± 0.23	??4.44±0.96 ??3.95±0.66	??＜0.01 ??＜0.01
Whole blood contrast viscosity hangs down shear	Man: 6.99 ± 1.15 woman: 5.71 ± 1.21	??6.98±1.41 ??5.68±1.07	??＜0.01 ??＜0.01	The high shear of whole blood contrast viscosity	Man: 4.78 ± 1.71 woman: 4.65 ± 0.23	??4.44±0.96 ??3.95±0.66	??＜0.01 ??＜0.01
Whole blood contrast viscosity hangs down shear	Man: 6.99 ± 1.15 woman: 5.71 ± 1.21	??6.98±1.41 ??5.68±1.07	??＜0.01 ??＜0.01	Whole blood reduction ratio viscosity is low cuts	Man: 13.23 ± 3.15 woman: 12.51 ± 1.30	??12.58±2.35 ??11.22±2.29	??＜0.01 ??＜0.01
Plasma viscosity	Man: 1.88 ± 0.37 woman: 1.94 ± 0.42	??1.65±0.15 ??1.71±0.15	??＜0.06 ??＜0.05	Whole blood reduction ratio viscosity is low cuts	Man: 13.23 ± 3.15 woman: 12.51 ± 1.30	??12.58±2.35 ??11.22±2.29	??＜0.01 ??＜0.01
Plasma viscosity	Man: 1.88 ± 0.37 woman: 1.94 ± 0.42	??1.65±0.15 ??1.71±0.15	??＜0.06 ??＜0.05	Erythrocyte sedimentation rate (mm/h)	Man: 21.47 ± 19.09 woman: 36.25 ± 27.19	??12±8 ??12±9	??＞0.05 ??＜0.05
ESR equation K value	Man: 86.60 ± 36.61 woman: 90.36 ± 39.20	??59.80±39.59 ??75.46±36.98	??＞0.05 ??＞0.05	Erythrocyte sedimentation rate (mm/h)	Man: 21.47 ± 19.09 woman: 36.25 ± 27.19	??12±8 ??12±9	??＞0.05 ??＜0.05
ESR equation K value	Man: 86.60 ± 36.61 woman: 90.36 ± 39.20	??59.80±39.59 ??75.46±36.98	??＞0.05 ??＞0.05	Hematid specific volume (%)	Man: 49.57 ± 8.75 woman: 42.4 ± 8.70	??47±7 ??42±4	??＜0.01 ??＜0.01

Can find out with treatment bleeding from anus rheology index notable difference (P＜0.05 or P＜0.01) is arranged before the treatment from last table.

Easypro stomach miraculous cure thing of the present invention forms and content is: Radix Astragali 20g Radix Aucklandiae 10g Fructus Amomi 10g Rhizoma Atractylodis 5g Radix Salviae Miltiorrhizae 30g Cortex Magnoliae Officinalis 10g Fructus Aurantii Immaturus 10g Radix Curcumae 15g Rhizoma Corydalis 20g Os Sepiae 10g Rhizoma Chuanxiong 15g Radix Glycyrrhizae 3g

Capsule concocting method of the present invention is:

1, in advance with Rhizoma Atractylodis, Fructus Aurantii Immaturus wheat bran parching to brown, Cortex Magnoliae Officinalis is soaked airing after 24 hours with gingerade, airing after Rhizoma Corydalis, the Radix Curcumae vinegar system, the Radix Astragali, the Radix Aucklandiae, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong fetch earth cool in, Fructus Amomi is given birth to and is used with Guangdong Fructus Amomi shell, Os Sepiae.

2, above various medicines will be asked for a back of mixing according to part by weight separately pulverizes.

3, after the medicinal mixture after will pulverizing filters with 100 orders-120 mesh sieve, do baking sterilization 4-6 hour 100 ℃ of-120 ℃ of temperature ranges.

4, will do the common capsule for medicine of powdered drug uniform device after the baking sterilization.

5, at last finished capsule product is sterilized with stand-by once more at 60 ℃ of temperature conditions.

Claims

1, a kind of Shuweiping-drug for curing gastropathy Chinese patent medicine is characterized in that this medicine, is made up of the medicine of following composition and corresponding weight thereof:

Radix Astragali 20g Radix Aucklandiae 10g Fructus Amomi 10g Rhizoma Atractylodis 5g Radix Salviae Miltiorrhizae 30g

Cortex Magnoliae Officinalis 10g Fructus Aurantii Immaturus 10g Radix Curcumae 15g Rhizoma Corydalis 20g Os Sepiae 10g

Rhizoma Chuanxiong 15g Radix Glycyrrhizae 3g

2, capsule concocting method of the present invention is:

1., in advance with Rhizoma Atractylodis, Fructus Aurantii Immaturus wheat bran parching to brown, Cortex Magnoliae Officinalis is soaked airing after 24 hours with gingerade, airing after Rhizoma Corydalis, the Radix Curcumae vinegar system, the Radix Astragali, the Radix Aucklandiae, Radix Salviae Miltiorrhizae, the Rhizoma Chuanxiong airing that fetches earth, Fructus Amomi is given birth to Guangdong Fructus Amomi shell, Os Sepiae and is used.

2., above various medicines will be asked for a back of mixing according to part by weight separately pulverizes.

3., after the medicinal mixture after will pulverizing filters with 100 orders-120 mesh sieve, do baking sterilization 4-6 hour 100 ℃ of-120 ℃ of temperature ranges.

4., will do baking sterilization back powdered drug uniform device common capsule for medicine.

5., at last finished capsule product is sterilized with stand-by once more at 60 ℃ of temperature conditions.