CN1063664C - Chinese patent medicine for treating gastrosis - Google Patents

Chinese patent medicine for treating gastrosis Download PDF

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Publication number
CN1063664C
CN1063664C CN98122151A CN98122151A CN1063664C CN 1063664 C CN1063664 C CN 1063664C CN 98122151 A CN98122151 A CN 98122151A CN 98122151 A CN98122151 A CN 98122151A CN 1063664 C CN1063664 C CN 1063664C
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parts
rhizoma
radix
bletillae
chinese patent
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CN1238982A (en
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刘明国
赵义军
梁树明
李根平
郑庆林
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HUALU PHARMACETICULAR FACTORY
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HUALU PHARMACETICULAR FACTORY
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Abstract

The present invention relates to a medicine composition for treating gastropathy, which is a Chinese patent medicine which mainly treats gastric discomfort caused by peptic ulcer. The present invention is a medicine which is prepared from raw materials comprising components of the following parts by weight: 110 to 250 parts of cuttlefish bone, 20 to 60 parts of notoginseng, 45 to 150 parts of corydalis tuber, 30 to 90 parts of bletilla tuber, 15 to 50 parts of amomun fruit, 20 to 80 parts of magnolia bark, 20 to 80 parts of aucklandia root, 10 to 30 parts of lignum aquilariae, 5 to 20 parts of galangal, 5 to 40 parts of rhubarb and 20 to 80 parts of fritillariae thunbergii. Clinic and animal experiments indicate that the medicine of the present invention comprising the components has the advantages of vital energy circulation promotion, hemostasis, spleen and stomach warming for dispelling cold, acid restraining, granulation promoting and stomach harmonization. The present invention has an obvious effect rate of 100% and a cure rate of 92%.

Description

A kind of Chinese patent medicine for the treatment of gastropathy
The present invention relates to a kind of pharmaceutical composition for the treatment of gastropathy, is a kind of main treatment because of the Chinese patent medicine of stomach discomfort due to the peptic ulcer.
Because gastropathy is commonly encountered diseases, frequently-occurring disease, so it is various to cause treating the herbal species of gastropathy.But its specific aim of the Chinese medicine of existing various treatment gastropathy is lower, generally all treats various stomach discomfort, can not be at a certain definite stomach discomfort treatment.The medicine of treatment peptic ulcer, the Western medicine curative effect is better, but its side effect is bigger, particularly gastrointestinal zest patient often is difficult to stand.The Chinese medicine electuary shows that curative effect is not good enough when the treatment peptic ulcer.The absorbance of Chinese medicinal capsule is than electuary height, but do not have a kind of Chinese medicinal capsule can treat the disease of peptic ulcer as yet.
The objective of the invention is, a kind of Chinese patent medicine for the treatment of peptic ulcer gastropathy is provided, make it have the advantage of the sense of discomfort due to can very fast alleviation peptic ulcer, and have the advantage of promoting the circulation of QI to relieve pain, warming spleen and stomach for dispelling cold, antacid granulation promoting, stomach function regulating, and has the advantage that does not stimulate the stomach infections, do not damage people body-centered, liver, kidney.
Chinese patent medicine of the present invention is the medicament of making by the raw material of following weight ratio: it has Endoconcha Sepiae 110-250 part, Radix Notoginseng 20-60 part, Rhizoma Corydalis 45-150 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 30-90 part, Fructus Amomi 15-50 part, Cortex Magnoliae Officinalis 20-80 part, Radix Aucklandiae 20-80 part, Lignum Aquilariae Resinatum 10-30 part, Rhizoma Alpiniae Officinarum 5-20 part, Radix Et Rhizoma Rhei 5-40 part, Bulbus Fritillariae Thunbergii 20-80 part.Wherein the weight proportion of each raw material is: Endoconcha Sepiae 150-230 part, Radix Notoginseng 30-50 part, Rhizoma Corydalis 70-110 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 40-70 part, Fructus Amomi 20-40 part, Cortex Magnoliae Officinalis 30-60 part, Radix Aucklandiae 30-60 part, Lignum Aquilariae Resinatum 10-20 part, Rhizoma Alpiniae Officinarum 5-15 part, Radix Et Rhizoma Rhei 10-30 part, Bulbus Fritillariae Thunbergii 50-90 part.Wherein the weight proportion of each raw material is: 50 parts of 170 parts of Endoconcha Sepiaes, 30 parts of Radix Notoginseng, 70 parts of Rhizoma Corydalis, 38 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 20 parts of Fructus Amomis, 30 parts of Cortex Magnoliae Officinalis, 35 parts of the Radix Aucklandiae, 10 parts of Lignum Aquilariae Resinatum, 5 parts of Rhizoma Alpiniae Officinarums, Radix Et Rhizoma Rhei 10, Bulbus Fritillariae Thunbergii.Wherein the weight proportion of each raw material is: 210 parts of Endoconcha Sepiaes, 40 parts of Radix Notoginseng, 90 parts of Rhizoma Corydalis, 55 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 30 parts of Fructus Amomis, 40 parts of Cortex Magnoliae Officinalis, 50 parts of the Radix Aucklandiae, 17 parts of Lignum Aquilariae Resinatum, 10 parts of Rhizoma Alpiniae Officinarums, 13 parts of Radix Et Rhizoma Rhei, 70 parts of Bulbus Fritillariae Thunbergiis.Described medicament is a capsule.The preparation method of Chinese patent medicine of the present invention is: get Endoconcha Sepiae and Radix Notoginseng, the Pseudobulbus Bletillae (Rhizoma Bletillae), Fructus Amomi, Lignum Aquilariae Resinatum, Radix Et Rhizoma Rhei powder is broken into fine powder, sieve; Rhizoma Corydalis, Bulbus Fritillariae Thunbergii is ground into coarse powder, and the percolation according under the fluid extract item carries out percolation with 60% ethanol, the collection liquid of filtering, reclaim ethanol, get medicinal liquid, Cortex Magnoliae Officinalis, the Radix Aucklandiae, Rhizoma Alpiniae Officinarum extracts volatile oil, aqueous solution after distillation device is in addition collected, medicinal residues and remaining Endoconcha Sepiae decoct with water secondary, and each 1 hour, collecting decoction, filter, aqueous solution after filtrate and above-mentioned medicinal liquid and the distillation merges, and is condensed into the thick paste shape, makes dried cream, be ground into fine powder, add fine powders such as Endoconcha Sepiae, mixing, the Rhizoma Corydalis after extracting with percolation again, Bulbus Fritillariae Thunbergii is pulverized and is fine powder, the dry volatile oil mixing that adds divides shape to become promptly.
Endoconcha Sepiae antacid stomach function regulating relieves the pain in the component of the present invention, astringing to arrest bleeding, the monarch drug in the granulation promoting damp eliminating side of being.The Endoconcha Sepiae active ingredient is calcium carbonate and phlegmatic temperament, can antacid, hemostasis, pain relieving, cooperation other drug all have curative effect preferably to Peptic Ulcers and hemorrhage, the perforation that cause.Ministerial drug with Radix Notoginseng, Rhizoma Corydalis, the Pseudobulbus Bletillae (Rhizoma Bletillae) side of being.Radix Notoginseng is the key medicine of hemostasia and dissipation blood stasis, and can subside a swelling again relieves the pain.Radix Notoginseng has stronger regulating action (comprising similar soothing liver-QI for relieving depression function) to central nervous excitation, calmness, safety.And significant analgesia role arranged, the effect of flesh pine, the enhancing human body immunity effect, strengthen the liver detoxification ability, hepatoprotective effect is arranged, can obviously increase the bile secretion facilitating digestion, anastalsis (platelet increasing number and activity shorten bleeding time and clotting time) is arranged, the effect of invigorating blood circulation again (inhibition platelet aggregation), and can promote RNM-DNA protein synthesis in the bone marrow, reduce the disintegration of cell nRNA, thereby the enhancing body resisting fatigue there is antiinflammatory action again, the acute inflammation card there is tangible antagonism, various destructive stimuluses are had nonspecific resistance.Rhizoma Corydalis has tangible analgesic effect and stronger calmness, stable and syngignoscism, can resist the rat experiment ulcer significantly, the ulcer that causes of pylorus ligation and aspirin particularly, gastric secretion is had inhibitory action, and it is irrelevant that it suppresses gastric secretion and antiulcer effect and parasympathetic blocking-up.Pseudobulbus Bletillae (Rhizoma Bletillae) function is a hemostasia and detumescence, promoting tissue regeneration and ulcer healing.According to modern pharmacology research, the Pseudobulbus Bletillae (Rhizoma Bletillae) has tangible anastalsis, and its anastalsis is relevant with its contained gluey composition; borrow its high viscosity, form certain thickness gluey film under one's belt and be attached on the ulcer surface, the routed noodle soup of protection; thereby make blockage of perforations, tolerant stopping to be outflowed in the stomach.With Fructus Amomi, Cortex Magnoliae Officinalis, the Radix Aucklandiae, Lignum Aquilariae Resinatum, Rhizoma Alpiniae Officinarum is adjuvant drug, the Fructus Amomi circulation of qi promoting, transfer in stomach function regulating, be amusing.Control it with Fructus Amomi, it is the most prompt to prove effective.Fructus Amomi Wen Xinxiang looses, and preventing or arresting vomiting leads to diaphragm, reaches gas also, and antiabortive relieving distension reaches middle gas also ... general with the Radix Aucklandiae, You Su cures the disease.Fructus Amomi is the good medicine that is good for the stomach, and can drive away the corrupt gas of gastric, and the antiphlogistic antibacterial effect is arranged.The circulation of qi promoting of Cortex Magnoliae Officinalis function relieves the pain, warming middle-JIAO dampness.The kind gas that stagnates in the stomach that removes.Cortex Magnoliae Officinalis has stronger antibacterial and anti-inflammation functions and improves the effect of liver essence pathological changes; The hot hardship of loosing of the Radix Aucklandiae is fallen, and the current gastrointestinal three warmers stagnation of QI can circulation of qi promoting relieve the pain invigorating the stomach and promoting digestion; Lignum Aquilariae Resinatum is flat contrary based on the circulation of qi promoting sending down the abnormal ascending QI that relieves the pain, doubleization taste turbid damp, and it is warm in nature and not dry, and is capable and do not let out, and spleen assisting and kidney-attaining is taken the photograph fire and is returned unit, the Rhizoma Alpiniae Officinarum warming stomach for dispelling cold, helping digestion relieves the pain.With Radix Et Rhizoma Rhei, folding shellfish is messenger drug, the Radix Et Rhizoma Rhei intestinal stasis relieving that purges heat, logical intestinal; The Bulbus Fritillariae Thunbergii heat clearing away, the dissipating depression of QI eliminating stagnation is share with Radix Et Rhizoma Rhei, can prevent the warm-dryness syndrome of all medicines, can prevent the constipation of clothes for a long time of Endoconcha Sepiae warm-dryness syndrome again.Radix Et Rhizoma Rhei is to the tangible antibacterial action of multiple gram-positive bacterium and part negative bacteria, can shorten clotting time and anastalsis is arranged; Bulbus Fritillariae Thunbergii has certain the acid effect that presses down and tangible antiulcer action.
The medicine of component of the present invention shows to have the circulation of qi promoting hemostasis through clinical and animal experiment, the advantage of warming spleen and stomach for dispelling cold, antacid granulation promoting, stomach function regulating, the advantage of the sense of discomfort due to can very fast alleviation peptic ulcer, and have and do not stimulate the stomach infections, the advantage of people body-centered, liver, kidney do not damaged.Obvious effective rate of the present invention is 100%, and cure rate is 92%.
The embodiment of the invention following (each component of the present invention is all by weight percentage):
Embodiment 1
110 parts of Endoconcha Sepiaes, 20 parts of Radix Notoginseng, 45 parts of Rhizoma Corydalis, 30 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of Fructus Amomis, 20 parts of Cortex Magnoliae Officinalis, 20 parts of the Radix Aucklandiae, 10 parts of Lignum Aquilariae Resinatum, 5 parts of Rhizoma Alpiniae Officinarums, 5 parts of Radix Et Rhizoma Rhei, 20 parts of Bulbus Fritillariae Thunbergiis.
Embodiment 2
120 parts of Endoconcha Sepiaes, 40 parts of Radix Notoginseng, 70 parts of Rhizoma Corydalis, 50 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 30 parts of Fructus Amomis, 50 parts of Cortex Magnoliae Officinalis, 50 parts of the Radix Aucklandiae, 10 parts of Lignum Aquilariae Resinatum, 10 parts of Rhizoma Alpiniae Officinarums, 25 parts of Radix Et Rhizoma Rhei, 90 parts of Bulbus Fritillariae Thunbergiis.
Embodiment 3
170 parts of Endoconcha Sepiaes, 30 parts of Radix Notoginseng, 70 parts of Rhizoma Corydalis, 38 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 20 parts of Fructus Amomis, 30 parts of Cortex Magnoliae Officinalis, 35 parts of the Radix Aucklandiae, 10 parts of Lignum Aquilariae Resinatum, 5 parts of Rhizoma Alpiniae Officinarums, 10 parts of Radix Et Rhizoma Rhei, 50 parts of Bulbus Fritillariae Thunbergiis.
Embodiment 4
210 parts of Endoconcha Sepiaes, 40 parts of Radix Notoginseng, 90 parts of Rhizoma Corydalis, 55 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 30 parts of Fructus Amomis, 40 parts of Cortex Magnoliae Officinalis, 50 parts of the Radix Aucklandiae, 17 parts of Lignum Aquilariae Resinatum, 10 parts of Rhizoma Alpiniae Officinarums, 13 parts of Radix Et Rhizoma Rhei, 70 parts of Bulbus Fritillariae Thunbergiis.
Embodiment 5
240 parts of Endoconcha Sepiaes, 50 parts of Radix Notoginseng, 100 parts of Rhizoma Corydalis, 60 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 45 parts of Fructus Amomis, 70 parts of Cortex Magnoliae Officinalis, 60 parts of the Radix Aucklandiae, 25 parts of Lignum Aquilariae Resinatum, 20 parts of Rhizoma Alpiniae Officinarums, 30 parts of Radix Et Rhizoma Rhei, 100 parts of Bulbus Fritillariae Thunbergiis.
Embodiment 6
250 parts of Endoconcha Sepiaes, 55 parts of Radix Notoginseng, 120 parts of Rhizoma Corydalis, 33 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of Fructus Amomis, 60 parts of Cortex Magnoliae Officinalis, 65 parts of the Radix Aucklandiae, 30 parts of Lignum Aquilariae Resinatum, 15 parts of Rhizoma Alpiniae Officinarums, 35 parts of Radix Et Rhizoma Rhei, 120 parts of Bulbus Fritillariae Thunbergiis.
Embodiment 7
150 parts of Endoconcha Sepiaes, 60 parts of Radix Notoginseng, 140 parts of Rhizoma Corydalis, 80 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 50 parts of Fructus Amomis, 80 parts of Cortex Magnoliae Officinalis, 80 parts of the Radix Aucklandiae, 10 parts of Lignum Aquilariae Resinatum, 20 parts of Rhizoma Alpiniae Officinarums, 40 parts of Radix Et Rhizoma Rhei, 150 parts of Bulbus Fritillariae Thunbergiis.
Embodiment 8
200 parts of Endoconcha Sepiaes, 45 parts of Radix Notoginseng, 140 parts of Rhizoma Corydalis, 90 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 35 parts of Fructus Amomis, 70 parts of Cortex Magnoliae Officinalis, 70 parts of the Radix Aucklandiae, 20 parts of Lignum Aquilariae Resinatum, 10 parts of Rhizoma Alpiniae Officinarums, 30 parts of Radix Et Rhizoma Rhei, 170 parts of Bulbus Fritillariae Thunbergiis.
Get Endoconcha Sepiae and Radix Notoginseng, the Pseudobulbus Bletillae (Rhizoma Bletillae), Fructus Amomi, Lignum Aquilariae Resinatum, Radix Et Rhizoma Rhei powder is broken into fine powder, sieve; Rhizoma Corydalis, Bulbus Fritillariae Thunbergii is ground into coarse powder, and the percolation according under the fluid extract item carries out percolation with 60% ethanol, the collection liquid of filtering, reclaim ethanol, get medicinal liquid, Cortex Magnoliae Officinalis, the Radix Aucklandiae, Rhizoma Alpiniae Officinarum extracts volatile oil, aqueous solution after distillation device is in addition collected, medicinal residues and remaining Endoconcha Sepiae decoct with water secondary, and each 1 hour, collecting decoction, filter, aqueous solution after filtrate and above-mentioned medicinal liquid and the distillation merges, and is condensed into the thick paste shape, makes dried cream, be ground into fine powder, add fine powders such as Endoconcha Sepiae, mixing, the Rhizoma Corydalis after extracting with percolation again, Bulbus Fritillariae Thunbergii is pulverized and is fine powder, the dry volatile oil mixing that adds divides shape to become promptly.

Claims (6)

1, a kind of Chinese patent medicine for the treatment of gastropathy is characterized in that: it is the medicament of being made by the following weight proportion raw material: Endoconcha Sepiae 110-250 part, Radix Notoginseng 20-60 part, Rhizoma Corydalis 45-150 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 30-90 part, Fructus Amomi 15-50 part, Cortex Magnoliae Officinalis 20-80 part, Radix Aucklandiae 20-80 part, Lignum Aquilariae Resinatum 10-30 part, Rhizoma Alpiniae Officinarum 5-20 part, Radix Et Rhizoma Rhei 5-40 part, Bulbus Fritillariae Thunbergii 20-80 part.
2, a kind of Chinese patent medicine for the treatment of gastropathy according to claim 1, it is characterized in that: wherein the weight proportion of each raw material is: Endoconcha Sepiae 150-230 part, Radix Notoginseng 30-50 part, Rhizoma Corydalis 70-110 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 40-70 part, Fructus Amomi 20-40 part, Cortex Magnoliae Officinalis 30-60 part, Radix Aucklandiae 30-60 part, Lignum Aquilariae Resinatum 10-20 part, Rhizoma Alpiniae Officinarum 5-15 part, Radix Et Rhizoma Rhei 10-30 part, Bulbus Fritillariae Thunbergii 50-90 part.
3, a kind of Chinese patent medicine for the treatment of gastropathy according to claim 1, it is characterized in that: wherein the weight proportion of each raw material is: 50 parts of 170 parts of Endoconcha Sepiaes, 30 parts of Radix Notoginseng, 70 parts of Rhizoma Corydalis, 38 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 20 parts of Fructus Amomis, 30 parts of Cortex Magnoliae Officinalis, 35 parts of the Radix Aucklandiae, 10 parts of Lignum Aquilariae Resinatum, 5 parts of Rhizoma Alpiniae Officinarums, Radix Et Rhizoma Rhei 10, Bulbus Fritillariae Thunbergii.
4, a kind of Chinese patent medicine for the treatment of gastropathy according to claim 1, it is characterized in that: wherein the weight proportion of each raw material is: 210 parts of Endoconcha Sepiaes, 40 parts of Radix Notoginseng, 90 parts of Rhizoma Corydalis, 55 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 30 parts of Fructus Amomis, 40 parts of Cortex Magnoliae Officinalis, 50 parts of the Radix Aucklandiae, 17 parts of Lignum Aquilariae Resinatum, 10 parts of Rhizoma Alpiniae Officinarums, 13 parts of Radix Et Rhizoma Rhei, 70 parts of Bulbus Fritillariae Thunbergiis.
5, according to claim 1,2,3 or 4 described a kind of Chinese patent medicines for the treatment of gastropathy, it is characterized in that: described medicament is a capsule.
6, the preparation method of the Chinese patent medicine of the treatment gastropathy of claim 1 is characterized in that: get Endoconcha Sepiae and Radix Notoginseng, the Pseudobulbus Bletillae (Rhizoma Bletillae), Fructus Amomi, Lignum Aquilariae Resinatum, Radix Et Rhizoma Rhei powder is broken into fine powder, sieve; Rhizoma Corydalis, Bulbus Fritillariae Thunbergii is ground into coarse powder, and the percolation according under the fluid extract item carries out percolation with 60% ethanol, the collection liquid of filtering, reclaim ethanol, get medicinal liquid, Cortex Magnoliae Officinalis, the Radix Aucklandiae, Rhizoma Alpiniae Officinarum extracts volatile oil, aqueous solution after distillation device is in addition collected, medicinal residues and remaining Endoconcha Sepiae decoct with water secondary, and each 1 hour, collecting decoction, filter, aqueous solution after filtrate and above-mentioned medicinal liquid and the distillation merges, and is condensed into the thick paste shape, makes dried cream, be ground into fine powder, add fine powders such as Endoconcha Sepiae, mixing, the Rhizoma Corydalis after extracting with percolation again, Bulbus Fritillariae Thunbergii is pulverized and is fine powder, the dry volatile oil mixing that adds is distributed into promptly.
CN98122151A 1998-12-23 1998-12-23 Chinese patent medicine for treating gastrosis Expired - Fee Related CN1063664C (en)

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Application Number Priority Date Filing Date Title
CN98122151A CN1063664C (en) 1998-12-23 1998-12-23 Chinese patent medicine for treating gastrosis

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CN1063664C true CN1063664C (en) 2001-03-28

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Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1102053C (en) * 2000-01-27 2003-02-26 王念夫 Weitong capsule for curing stomach-ache
CN1966036B (en) * 2006-11-25 2011-05-25 李勇奇 Chinese medicine for treating gastrointestinal disease and preparation method thereof
CN101628097B (en) * 2008-07-15 2011-05-25 毛晓红 Stomach health powder
CN102961662B (en) * 2012-11-09 2014-06-25 山东华鲁制药有限公司 Medicine for treating gastric ulcer and preparation method thereof
CN105833165A (en) * 2016-06-03 2016-08-10 吕灿利 Traditional Chinese medicine composition for treating gastric disease
CN106421320A (en) * 2016-10-26 2017-02-22 黔西南州神力中草药应用开发研究所 Medicine for treating gastropathy and preparation method of medicine

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1098635A (en) * 1993-08-10 1995-02-15 赵成启 The medicine and the manufacture method of treatment gastropathy
CN1110924A (en) * 1994-04-28 1995-11-01 余慕良 Effective drug for gastric disease
CN1113798A (en) * 1994-06-18 1995-12-27 臧明礼 Chinese drug for curing gastropathy
CN1164401A (en) * 1996-06-13 1997-11-12 杨和华 Shuweiping-drug for curing gastropathy
CN1178108A (en) * 1996-09-28 1998-04-08 郑文学 Weixiandan as medicine for gastropathy

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1098635A (en) * 1993-08-10 1995-02-15 赵成启 The medicine and the manufacture method of treatment gastropathy
CN1110924A (en) * 1994-04-28 1995-11-01 余慕良 Effective drug for gastric disease
CN1113798A (en) * 1994-06-18 1995-12-27 臧明礼 Chinese drug for curing gastropathy
CN1164401A (en) * 1996-06-13 1997-11-12 杨和华 Shuweiping-drug for curing gastropathy
CN1178108A (en) * 1996-09-28 1998-04-08 郑文学 Weixiandan as medicine for gastropathy

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