CN102727860A - Medicament for treating intestinal adhesion and bowel obstruction after abdominal operation and preparation method thereof - Google Patents
Medicament for treating intestinal adhesion and bowel obstruction after abdominal operation and preparation method thereof Download PDFInfo
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- CN102727860A CN102727860A CN2012102519733A CN201210251973A CN102727860A CN 102727860 A CN102727860 A CN 102727860A CN 2012102519733 A CN2012102519733 A CN 2012102519733A CN 201210251973 A CN201210251973 A CN 201210251973A CN 102727860 A CN102727860 A CN 102727860A
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Abstract
The invention relates to a medicament for treating intestinal adhesion and bowel obstruction after an abdominal operation and a preparation method thereof, and belongs to the difficult-and-rare-case category in the field of traditional Chinese medicine. The medicament is prepared by 14 types of medicines such as red ginseng, angelica and rhubarb into dosage forms of oral liquid and capsules so as to be convenient for patients to take in emergency. The medicament aims at impaired and disordered bowel function, as well as blood stasis, congestion and edema, necrosis, inflammatory adhesion, rebond hypertrophy and other pathological states on injured parts caused by damaging mesentery, veins, nerves and vessels or destroying the original state of intestinal spiral arrangement after liver, gallbladder, spleen, pancreas, stomach, intestine, appendix, bladder, uterus of women, accessories, cesarean section and other abdominal operations. The other reason for the disease is that postoperative undermining of the constitution of a person, weakness, abdomen qi impassability, or qi stagnation caused by catching a chill, damp turbidity, blood stasis, improper diet and bad mood result in intestinal adhesion, obstruction and other acute abdomen. After long-term clinical application, the medicament has definite curative effect, and currently a pure traditional Chinese medicine preparation similar to the medicament has not been found.
Description
One, technical field:
The present invention is that a kind of abdominal postoperative of treating is lost medicine that intestinal adhesion and intestinal block and preparation method thereof, belongs to tcm field, the difficult disease category.
Two, background technology
The present invention be directed to multiple abdominal operation like postoperatives such as liver, gallbladder, spleen, pancreas, stomach, intestinal, vermiform appendix, bladder, women uterus, adnexa, cesarean; Damage mesentery, venation, nerve, blood vessel; Or destroyed the previous status that intestinal spirals and arranges; Cause the impaired disorder of function of intestinal canal; And cause pathological states such as damage location blood stasis, hyperemia, edema, necrosis, inflammation, adhesion, scar hyperplasia, and occur that abdominal distention, stomachache, borborygmus, stool are smooth, belch, arrow gas reduces or defecation not on the two, three; Gastrointestinal convulsion very then appears, spasm, and enclosed mass in the abdomen, has channeling breast abdomen, tormina, vomiting can not defecate, does not have the gas of arrow, and intestinal such as be no longer capable of either eating or drinking blocks serious symptoms, and the state of an illness is shown effect repeatedly, threat to life; The person that meets the surgical condition can consider to perform the operation once more and remove adhesion or block focus; Patient's underwent operative of having removes adhesion, block focus after, occur adhesion again once again, block, the long-term ailing health that torments is extremely weak, can not bear operative treatment again.Some patient experiences repeatedly abdominal operation because of the internal organs various diseases, and wound hidden danger very easily causes intestinal adhesion and intestinal obstruction illness.
Another reason of primary disease is: postoperative is sapped one's vitality, and taste intestinal function void declines, and fortuneization is unable, functional activity of QI being not smooth; FU QI being obstructed, or because of catch cold, turbid damp, blood stasis, intemperance of taking food; Mood is not smooth, the strongly fragrant resistance of mechanism of qi, and abnormal ascending-descending of QI causes adhesion, blocks; Be accumulated into abdominal mass, lead to chronic persistent ailment, do not heal for many years, misery very.
I once treated example surplus this patient 100, and it is to fail to effect a radical cure adhesion through cutting open the belly once more, block the patient that 30 many cases are arranged, and adopts the recovery from illness rehabilitation of we's treatment back.For saving more patient, the etiology and pathogenesis of further investigation primary disease is refined and is filled a prescription and completion the present invention in the long term medical practice.The clinical practice determined curative effect is not found and the similar pure Chinese medicinal preparation of the present invention through retrieval as yet.The intestinal adhesion that the present invention causes other reason, intestinal obstruction also have significant curative effect.
Three, summary of the invention
1, medicine of the present invention and weight proportion thereof are:
Radix Ginseng Rubra 10-50 part, Radix Astragali 15-60 part, Ramulus Cinnamomi 10-40 part, Rhizoma Zingiberis 10-30 part, Radix Paeoniae Alba 10-50 part, Radix Angelicae Sinensis 10-40 part, Rhizoma Chuanxiong 10-40 part, triangular 10-30 part, Rhizoma Curcumae 10-30 part, Radix Et Rhizoma Rhei 10-40 part, Fructus Aurantii Immaturus 10-30 part, Cortex Magnoliae Officinalis 10-30 part, Radix Linderae 10-30 part, Radix Glycyrrhizae 10-30 part.
2, the preferred weight proportioning of medicine of the present invention is:
Radix Ginseng Rubra 15-50 part, Radix Astragali 20-60 part, Ramulus Cinnamomi 15-40 part, Rhizoma Zingiberis 10-30 part, Radix Paeoniae Alba 15-50 part, Radix Angelicae Sinensis 15-40 part, Rhizoma Chuanxiong 10-40 part, triangular 15-30 part, Rhizoma Curcumae 15-30 part, Radix Et Rhizoma Rhei 10-30 part, Fructus Aurantii Immaturus 10-30 part, Cortex Magnoliae Officinalis 10-30 part, Radix Linderae 10-30 part, Radix Glycyrrhizae 10-30 part.
3, the optimum weight proportioning of medicine of the present invention is:
30 parts of Radix Ginseng Rubra, 50 parts of the Radixs Astragali, 20 parts of Ramulus Cinnamomi, 20 parts of Rhizoma Zingiberiss, 30 parts of the Radix Paeoniae Albas, 30 parts of Radix Angelicae Sinensis, 30 parts of Rhizoma Chuanxiongs, triangular 20 parts, 20 parts of Rhizoma Curcumae, 30 parts of Radix Et Rhizoma Rhei, 20 parts of Fructus Aurantii Immaturuss, 20 parts of Cortex Magnoliae Officinalis, 20 parts of the Radixs Linderae, 20 parts in Radix Glycyrrhizae.
4, the present invention separates the side of prescription:
The present invention is admittedly just adopting Radix Ginseng Rubra, Radix Astragali QI invigorating; Ramulus Cinnamomi, Rhizoma Zingiberis warming spleen and stomach for dispelling cold collateral dredging; Radix Angelicae Sinensis, Rhizoma Chuanxiong, triangular, Rhizoma Curcumae blood circulation promoting and blood stasis dispelling removing food stagnancy; Is the Therapeutic Principle of benefit according to six internal organs to lead to, and adopts Radix Et Rhizoma Rhei, Fructus Aurantii Immaturus, Radix Linderae circulation of qi promoting purging FU-organs, removes blood stasis, stagnant; The Radix Paeoniae Alba, Radix Glycyrrhizae spasmolytic, relieving spasm to stop pain, full side's strengthening vital QI to eliminate pathogenic factors, compatibility is rigorous, determined curative effect.
5, the main effect of prescription drug of the present invention:
Radix Ginseng Rubra: these article merit is arrogated to oneself strongly invigorating primordial QI, declines so be used to save first deficiency of vital energy, and the depletion syndrome that faint pulse drink is exhausted, because of in losing blood greatly, big vomiting and diarrhoea, or prolonged illness serious disease vigour depletion person, that uses all has a good effect.The Radix Astragali: the gas of the kind spleen reinforcing lung of these article, the laudatory title of " length of QI invigorating " is arranged, again can the elevate a turnable ladder yang-energy, be used for sinking of QI of middle-JIAO, the chronic diarrhea proctoptosis, the internal organs prolapsus is used for deficiency of both QI and blood but qi-supplementing, blood-engendering is taken the photograph blood, again can the dispersion by invigorating granulation promoting, hold back ulcer and do not close up for a long time.Ramulus Cinnamomi: the hot temperature ability of these article warming the meridian and promoting blood circulation, dispersing cold for relieving pain, activating YANG and prormoting functioning of QI is controlled the cold coagulation stasis, coldness and pain in the epigastrium.Rhizoma Zingiberis: these article are hot, are the key medicine of warming spleen and stomach for dispelling cold, control the taste cold syndrome, no matter be to invade in the exogenous cold, or the deficiency-cold syndrome of taste YANG QI deficiency all can be used.The Radix Paeoniae Alba: these article total glycosides and peoniflorin have antiinflammatory, immunomodulating, calmness, convulsion, analgesic, spasmolytic, protect the liver, expand blood vessel, suppress antibacterial and some pathogenic fungus, regulating the liver and spleen, relieving spasm to stop pain effect.Radix Angelicae Sinensis: the hot row of the sweet benefit of these article, the Wen Tongzhi profit, have good enrich blood, invigorate blood circulation, analgesic effect, invigorating middle warmer has row, in the row benefit is arranged, and is the good medicine of invigorating blood circulation, to asthenia cold abdominalgia, rheumatic arthralgia, traumatic injury, carbuncle skin ulcer have waited good promoting blood circulation and stopping pain effect bitterly.Rhizoma Chuanxiong: the hot temperature of loosing of these article is logical, walks and does not keep, and is gas medicine in the blood, and to blood stasis, the stagnation of QI, cold coagulation pain person, that uses is the most suitable.Triangular: the circulation of qi promoting of these article removing blood stasis, the removing food stagnancy pain relieving, effect is similar with Rhizoma Curcumae, is used for the depressed heavily card of blood stasis; Right triangular blood part of going into partially, the merit of removing blood stasis is superior to Rhizoma Curcumae, and Rhizoma Curcumae is gone into edema caused by disorder of QI partially, and the merit of dispelling the stagnated QI is superior to triangular, and both refinforce each other to heighten the effect of a treatment to control all cards of stagnation of QI and blood.Rhizoma Curcumae: the hot hardship of loosing of these article lets out that temperature is logical, and the efficacy of a drug is quite strong, kind removing blood stasis circulation of qi promoting, and the removing food stagnancy pain relieving for the removing blood stasis abdominal mass key medicine that disappears, is used for stagnation of QI and blood more and heavily demonstrate,proves.Radix Et Rhizoma Rhei: the sedimentation of these article bitter cold, the violent benefaction of power has the title of " general ", and relieving constipation by purgation power is strong, and it is stagnant to be good at cleansing the intestines and stomach, and kind blood circulation promoting and blood stasis dispelling, and for controlling abdominal pain due to blood stasis, traumatic injury is hindered swollen good merchantable brand.Fructus Aurantii Immaturus: these article toil is slightly cold, and the stagnant power of letting out of falling of row is strong, is longer than brokenly the gas that stagnates, the row phlegm-damp, and removing food stagnancy stagnates, and removes the feeling of fullness distending pain.Cortex Magnoliae Officinalis: the bitter ability of these article therapeutic method to keep the adverse QI flowing downwards, suffering is with eliminating stagnation, but temperature dampness, the master goes into the taste large intestine channel, both can descend tangible reality full, can remove wetting of first shape again and expire, and merit is apt to dampness, circulation of qi promoting, removing food stagnancy is relievingd asthma.The Radix Linderae: these article suffering row temperature is logical, and up spleen lung is unclogged and readjusted the gas of breast abdomen, assigns the diffusing bladder cold air of kidney and bladder ability the kidney warming, removes the chest and abdomen swelling and pain of the cold strongly fragrant stagnation of QI.Radix Glycyrrhizae: effects such as the spleen reinforcing of these article tool, lung moistening, detoxifcation, emergency and medicine are widely used, so the title of " state is old " is arranged.
Four, method for preparing:
1, with drug purification of the present invention, drying is claimed sufficient deal by the optimum weight proportioning, closes even subsequent use.
2, with stock of drugs broken be coarser powder, add 8 times of drinking waters amount and soak 24h, whenever stir once at a distance from 8h.
3, will soak medicamental pulverata and water heated and boiled 1.5h behind the 24h, leaching liquid is crossed in cooling, again medicinal residues is added 6 times of amounts of water and boils 2h, crosses leaching liquid.
4, will decoct twice gained medicinal liquid and close even half h that boils, filter clarification.
5, will clarify medicinal liquid and press the conventional method for preparing of oral liquid, be prepared into oral liquid, the vial packing, every bottle of 20ml, the encapsulation sterilization, per 5 box-packed, be equipped with suction pipe.
6, be fine powder with the 1st stock of drugs micronizing of method for preparing, nontoxic capsule subpackage, the heavy 0.5g of grain, per 100 bottled sterilization sealings.
7, the oral liquid of medication preparation of the present invention, capsule are said dosage forms on any pharmaceutics.
Claims (8)
1. the invention discloses a kind of abdominal postoperative of treating and lose medicine that intestinal adhesion and intestinal block and preparation method thereof, it is characterized in that it is to be become by following medicine and weight combo thereof.
Radix Ginseng Rubra 10-50 part, Radix Astragali 15-60 part, Ramulus Cinnamomi 10-40 part, Rhizoma Zingiberis 10-30 part, Radix Paeoniae Alba 10-50 part, Radix Angelicae Sinensis 10-40 part, Rhizoma Chuanxiong 10-40 part, triangular 10-30 part, Rhizoma Curcumae 10-30 part, Radix Et Rhizoma Rhei 10-40 part, Fructus Aurantii Immaturus 10-30 part, Cortex Magnoliae Officinalis 10-30 part, Radix Linderae 10-30 part, Radix Glycyrrhizae 10-30 part.
2. the preferred weight proportioning of medicine of the present invention is:
Radix Ginseng Rubra 15-50 part, Radix Astragali 20-60 part, Ramulus Cinnamomi 15-40 part, Rhizoma Zingiberis 10-30 part, Radix Paeoniae Alba 15-50 part, Radix Angelicae Sinensis 15-40 part, Rhizoma Chuanxiong 10-40 part, triangular 15-30 part, Rhizoma Curcumae 15-30 part, Radix Et Rhizoma Rhei 10-30 part, Fructus Aurantii Immaturus 10-30 part, Cortex Magnoliae Officinalis 10-30 part, Radix Linderae 10-30 part, Radix Glycyrrhizae 10-30 part.
3. the optimum weight proportioning of medicine of the present invention is:
30 parts of Radix Ginseng Rubra, 50 parts of the Radixs Astragali, 20 parts of Ramulus Cinnamomi, 20 parts of Rhizoma Zingiberiss, 30 parts of the Radix Paeoniae Albas, 30 parts of Radix Angelicae Sinensis, 30 parts of Rhizoma Chuanxiongs, triangular 20 parts, 20 parts of Rhizoma Curcumae, 30 parts of Radix Et Rhizoma Rhei, 20 parts of Fructus Aurantii Immaturuss, 20 parts of Cortex Magnoliae Officinalis, 20 parts of the Radixs Linderae, 20 parts in Radix Glycyrrhizae.
4. with drug purification of the present invention, drying is claimed sufficient deal by the optimum weight proportioning, closes evenly, and broken is coarser powder, adds 8 times of amounts of drinking water and soaks 24h, whenever stirs once at a distance from 8h.
5. will soak medicamental pulverata and water heated and boiled 1.5h behind the 24h, leaching liquid is crossed in cooling, again medicinal residues is added 6 times of amounts of water and boils 2h, crosses leaching liquid, will decoct twice gained medicinal liquid and close even half h that boils, and filters, and clarifies.
6. will clarify medicinal liquid and press the conventional method for preparing of oral liquid, be prepared into oral liquid, the vial packing, every bottle of 20ml, the encapsulation sterilization, per 5 box-packed, be equipped with suction pipe.
7. be fine powder with the 1st stock of drugs micronizing of method for preparing, nontoxic capsule subpackage, the heavy 0.5g of grain, per 100 bottled sterilization sealings.
8. the oral liquid of medication preparation of the present invention, capsule prescription protection.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012102519733A CN102727860A (en) | 2012-07-08 | 2012-07-08 | Medicament for treating intestinal adhesion and bowel obstruction after abdominal operation and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2012102519733A CN102727860A (en) | 2012-07-08 | 2012-07-08 | Medicament for treating intestinal adhesion and bowel obstruction after abdominal operation and preparation method thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103520509A (en) * | 2013-10-25 | 2014-01-22 | 刘晓伟 | Traditional Chinese medicine for treating mesenteric panni culitis |
| CN103948617A (en) * | 2014-04-27 | 2014-07-30 | 王志伟 | Pharmaceutical composition for treating and preventing adhesion after abdominal operation |
| CN104324328A (en) * | 2014-11-20 | 2015-02-04 | 赵静 | Traditional Chinese medicine composition for ileus and preparation method of traditional Chinese medicine composition |
| CN104352992A (en) * | 2014-11-26 | 2015-02-18 | 黄红妹 | Traditional Chinese medicine composition for treating susceptible intestinal obstruction after colon tumor operation |
| CN104840928A (en) * | 2015-06-01 | 2015-08-19 | 新疆农业大学 | Compound preparation and application thereof in preparing medicines for treating intestinal spasm and intestinal obstruction diseases of horse |
| CN112933138A (en) * | 2021-03-05 | 2021-06-11 | 兴德堂(北京)医药研究院 | External bathing formula for intestinal obstruction |
-
2012
- 2012-07-08 CN CN2012102519733A patent/CN102727860A/en not_active Withdrawn
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103520509A (en) * | 2013-10-25 | 2014-01-22 | 刘晓伟 | Traditional Chinese medicine for treating mesenteric panni culitis |
| CN103948617A (en) * | 2014-04-27 | 2014-07-30 | 王志伟 | Pharmaceutical composition for treating and preventing adhesion after abdominal operation |
| CN103948617B (en) * | 2014-04-27 | 2017-02-08 | 青岛市中心医院 | Pharmaceutical composition for treating and preventing adhesion after abdominal operation |
| CN104324328A (en) * | 2014-11-20 | 2015-02-04 | 赵静 | Traditional Chinese medicine composition for ileus and preparation method of traditional Chinese medicine composition |
| CN104352992A (en) * | 2014-11-26 | 2015-02-18 | 黄红妹 | Traditional Chinese medicine composition for treating susceptible intestinal obstruction after colon tumor operation |
| CN104840928A (en) * | 2015-06-01 | 2015-08-19 | 新疆农业大学 | Compound preparation and application thereof in preparing medicines for treating intestinal spasm and intestinal obstruction diseases of horse |
| CN104840928B (en) * | 2015-06-01 | 2018-08-03 | 新疆农业大学 | It a kind of compound preparation and is applied in preparing treatment horse enterospasm and intestinal obstruction medicine |
| CN112933138A (en) * | 2021-03-05 | 2021-06-11 | 兴德堂(北京)医药研究院 | External bathing formula for intestinal obstruction |
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Application publication date: 20121017 |