CN116392400B - Crystalline amino acid facial cleanser and preparation method thereof - Google Patents
Crystalline amino acid facial cleanser and preparation method thereof Download PDFInfo
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- 150000001413 amino acids Chemical class 0.000 title claims abstract description 42
- 230000001815 facial effect Effects 0.000 title claims abstract description 13
- 238000002360 preparation method Methods 0.000 title abstract description 6
- 238000002425 crystallisation Methods 0.000 claims abstract description 30
- 230000008025 crystallization Effects 0.000 claims abstract description 30
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract description 27
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 24
- 239000004094 surface-active agent Substances 0.000 claims abstract description 21
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 19
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 19
- 239000006071 cream Substances 0.000 claims abstract description 16
- 238000000034 method Methods 0.000 claims description 11
- -1 laureth-6 sodium carboxylate Chemical class 0.000 claims description 5
- REVZBRXEBPWDRA-UHFFFAOYSA-N Stearyl citrate Chemical compound CCCCCCCCCCCCCCCCCCOC(=O)CC(O)(C(O)=O)CC(O)=O REVZBRXEBPWDRA-UHFFFAOYSA-N 0.000 claims description 3
- 239000004138 Stearyl citrate Substances 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 3
- 229940105132 myristate Drugs 0.000 claims description 3
- 229940079988 potassium cocoyl glycinate Drugs 0.000 claims description 3
- 235000019330 stearyl citrate Nutrition 0.000 claims description 3
- TUNFSRHWOTWDNC-UHFFFAOYSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCCC(O)=O TUNFSRHWOTWDNC-UHFFFAOYSA-N 0.000 claims description 3
- LRCFXGAMWKDGLA-UHFFFAOYSA-N dioxosilane;hydrate Chemical compound O.O=[Si]=O LRCFXGAMWKDGLA-UHFFFAOYSA-N 0.000 claims description 2
- 238000002156 mixing Methods 0.000 claims description 2
- 229960004029 silicic acid Drugs 0.000 claims description 2
- 239000011734 sodium Substances 0.000 claims description 2
- 229910052708 sodium Inorganic materials 0.000 claims description 2
- 229940065859 sodium cocoyl glycinate Drugs 0.000 claims description 2
- IKGKWKGYFJBGQJ-UHFFFAOYSA-M sodium;2-(dodecanoylamino)acetate Chemical compound [Na+].CCCCCCCCCCCC(=O)NCC([O-])=O IKGKWKGYFJBGQJ-UHFFFAOYSA-M 0.000 claims description 2
- 239000013078 crystal Substances 0.000 abstract description 23
- 230000000694 effects Effects 0.000 abstract description 8
- 238000004090 dissolution Methods 0.000 abstract description 3
- 230000002378 acidificating effect Effects 0.000 abstract description 2
- 239000000047 product Substances 0.000 description 19
- 230000000052 comparative effect Effects 0.000 description 14
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Natural products NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 8
- 239000002245 particle Substances 0.000 description 8
- 239000000126 substance Substances 0.000 description 7
- 238000012360 testing method Methods 0.000 description 7
- 239000002932 luster Substances 0.000 description 6
- 239000004471 Glycine Substances 0.000 description 5
- 239000000203 mixture Substances 0.000 description 5
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- 239000002253 acid Substances 0.000 description 4
- 239000000654 additive Substances 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 235000014113 dietary fatty acids Nutrition 0.000 description 3
- 239000000194 fatty acid Substances 0.000 description 3
- 229930195729 fatty acid Natural products 0.000 description 3
- 150000004665 fatty acids Chemical class 0.000 description 3
- 239000000945 filler Substances 0.000 description 3
- 238000001000 micrograph Methods 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 239000000344 soap Substances 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- 239000002562 thickening agent Substances 0.000 description 3
- RFVNOJDQRGSOEL-UHFFFAOYSA-N 2-hydroxyethyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCO RFVNOJDQRGSOEL-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- FPVVYTCTZKCSOJ-UHFFFAOYSA-N Ethylene glycol distearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCOC(=O)CCCCCCCCCCCCCCCCC FPVVYTCTZKCSOJ-UHFFFAOYSA-N 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 230000000996 additive effect Effects 0.000 description 2
- 239000012752 auxiliary agent Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 239000002537 cosmetic Substances 0.000 description 2
- 239000006185 dispersion Substances 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 239000006260 foam Substances 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 229940100608 glycol distearate Drugs 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 239000003607 modifier Substances 0.000 description 2
- 238000001556 precipitation Methods 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- OUNZARDETXBPIX-UHFFFAOYSA-N 2-(2-dodecoxyethoxy)acetic acid Chemical compound CCCCCCCCCCCCOCCOCC(O)=O OUNZARDETXBPIX-UHFFFAOYSA-N 0.000 description 1
- MQFYRUGXOJAUQK-UHFFFAOYSA-N 2-[2-[2-(2-octadecanoyloxyethoxy)ethoxy]ethoxy]ethyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCOCCOCCOCCOC(=O)CCCCCCCCCCCCCCCCC MQFYRUGXOJAUQK-UHFFFAOYSA-N 0.000 description 1
- RMTFNDVZYPHUEF-XZBKPIIZSA-N 3-O-methyl-D-glucose Chemical compound O=C[C@H](O)[C@@H](OC)[C@H](O)[C@H](O)CO RMTFNDVZYPHUEF-XZBKPIIZSA-N 0.000 description 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 description 1
- 238000005054 agglomeration Methods 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 230000032798 delamination Effects 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000003113 dilution method Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 description 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000010907 mechanical stirring Methods 0.000 description 1
- 239000002105 nanoparticle Substances 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000005185 salting out Methods 0.000 description 1
- 238000013077 scoring method Methods 0.000 description 1
- 238000001338 self-assembly Methods 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 229960001866 silicon dioxide Drugs 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 235000002639 sodium chloride Nutrition 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/413—Nanosized, i.e. having sizes below 100 nm
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
- Detergent Compositions (AREA)
Abstract
The invention discloses a crystalline amino acid facial cleanser and a preparation method thereof. The crystalline amino acid facial cleanser comprises the following components in parts by mass: 40 parts of glycerol, 12 parts of amino acid surfactant, 0.1-0.5 part of crystallization agent, 0.5-2 parts of crystallization regulator, 1-2 parts of citric acid and 15-20 parts of water. According to the invention, from the perspective of crystals, the crystal size and the crystal form of the amino acid surfactant in an alcohol-water system under the acidic condition are adjusted by adding a proper amount of the crystallization agent and the crystallization regulator, so that the purposes of increasing the stability of paste and improving the appearance of the paste are achieved. The crystalline amino acid cleansing cream disclosed by the invention has the advantages of good stability and hardness, obvious pearl effect and excellent dissolution property.
Description
Technical Field
The invention relates to the technical field of cosmetics, in particular to a crystalline amino acid facial cleanser and a preparation method thereof.
Background
The crystal amino acid facial cleanser is one of the popular facial cleanser in recent years, has the characteristics of mild ingredients, moderate detergency, no obvious tight feel of skin after the product is used, and the like, and is toughened by consumers. The product is usually used as a main surfactant of the product, and the characteristic that the acid structure of the glycine amino acid surfactant is insoluble in a solvent to precipitate crystals is utilized to form paste. However, such products often face the application problem of poor stability, mainly expressed by: the product has poor thermal stability when water is melted and separated out at a higher temperature; the product has low paste forming temperature, and layering, coarseness and the like are easy to occur after long-term placement; the hardness of the paste is difficult to control, and the pearl luster of the paste is often not obvious enough.
In order to solve the above problems, the prior art is generally improved by adding an auxiliary agent. Wherein for different problems, the added auxiliary agents comprise: (1) The thickening agent such as PEG-120 methyl glucose trioleate, PEG-150 distearate, xanthan gum, acrylic ester copolymer, hydroxypropyl cellulose and other self-thickening or auxiliary thickening macromolecules can obviously enhance the overall viscosity of the system, avoid the situation that paste is soft after crystals are dissolved at high temperature, and improve the thermal stability of the product to a certain extent; (2) The filler, such as sodium chloride, fatty acid, silicon dioxide, glycol distearate, glycol monostearate and other substances insoluble in the system, can increase the solid content of the product, ensure the solid content of the product to be maintained at a certain value, keep the paste stable, and generally needs to be added with a certain amount, generally more than 5%. Meanwhile, the fatty acid and the pearlizing agent (glycol distearate or glycol monostearate) in the fatty acid have the effect of improving the pearlizing effect of the paste.
The method is to add additives on the basis of the original method to achieve the purpose of stabilizing paste, however, the superposition of various additives can obviously influence the original performance of the amino acid surfactant. For example, the addition of a thickener masks the original pearlescent texture of cocoylglycine crystals, so that an extra pearlescent agent is required to enhance the pearlescent feel; excessive addition of filler easily breaks the original structure of the paste, and aggravates the phenomena of water separation, coarsening and the like, such as salting-out effect caused by sodium chloride. Moreover, the two methods cannot fundamentally solve the problems of product appearance and usability: when the product has better stability, the thickener and the filler in the product have more amounts, the paste is harder, and the paste is often not quickly dissolved and is easy to agglomerate when in use; when the usability of the product is good, the paste is soft, the stability is not enough, and the paste is easy to hydrate at high temperature.
Disclosure of Invention
The invention aims at overcoming the defects and shortcomings of the prior art and providing the crystalline amino acid facial cleanser. The crystalline amino acid cleansing cream has good stability and hardness, obvious pearlescent effect and excellent dissolution performance.
Another object of the present invention is to provide a method for preparing the above crystalline amino acid cleansing cream.
The aim of the invention is achieved by the following technical scheme: the crystalline amino acid cleansing cream comprises the following components in parts by mass: 40 parts of glycerol, 12 parts of amino acid surfactant, 0.1-0.5 part of crystallization agent, 0.5-2 parts of crystallization regulator, 1-2 parts of citric acid and 15-20 parts of water.
Preferably, the crystalline amino acid cleansing cream comprises the following components in parts by mass: 40 parts of glycerol, 12 parts of amino acid surfactant, 0.3 part of crystallization agent, 1 part of crystallization regulator, 1.6 parts of citric acid and 17-18 parts of water.
The amino acid surfactant is glycine amino acid surfactant; preferably, the amino acid surfactant is potassium cocoyl glycinate and/or sodium cocoyl glycinate.
The crystallization agent is solid powder which is insoluble in alcohol water, has a large specific surface and can be uniformly dispersed in an alcohol water system. The material can provide crystal nucleus or crystallization site for crystallization of main material in the system, and can greatly reduce the energy required by crystallization of main material. The proper amount of the substances is beneficial to the uniform precipitation of crystals, so that the problems of rough paste, agglomeration and the like caused by different crystal sizes are avoided, too much use of the substances can cause too early precipitation of crystals, so that the crystal particle size is too small, and the pearl formation of the product is not facilitated.
Preferably, the crystallization agent is nano-sized hydrated silica.
Preferably, the crystallization agent has an average particle size of 10 to 100nm. If the average particle size is too large, the powder cannot act as a crystallization agent, and if the particle size is too small, the cost is too high and the powder is easy to agglomerate.
Preferably, the crystallization modifier is at least one of polyglycerol-10 myristate, stearyl citrate and sodium laureth-6 carboxylate; more preferably, the crystallization modifier is polyglycerol-10 myristate, stearyl citrate and laureth-6 sodium carboxylate, and the mass ratio is 30-50:30-50:0-20 proportion. The crystallization regulator can influence the self-assembly of molecules in the crystallization process of substances, thereby regulating the crystal habit of the amino acid surfactant. For the same substance, molecules will always grow along a surface with low surface energy under the same environment, so that the crystalline morphology of the substance under the same environment is fixed, i.e. the crystalline habit of the substance under the environment. The crystal morphology significantly affects the apparent properties of the final paste: the needle-like crystals are easy to agglomerate, have poor fluidity and low bulk density, can greatly reduce the stability of the paste, and are shown as high-temperature dilution, delamination, water evolution after long-term storage and the like; the bulk crystal has good fluidity and high bulk density, and is a target crystal form of a crystal product.
For glycine-based amino acid surfactants, the surfactant has soap and acid structures as pH changes:
wherein, the soap type structure is water-soluble, and the foam performance is better; while the acid type structure is fat-soluble and the foam performance is poor. Therefore, when the pH of the system is 6-7, the glycine surfactant mainly takes an acid structure as a main part, and the glycine surfactant can precipitate crystals in an alcohol-water system and form paste. Meanwhile, the system still has a part of soap structure, so that the service performance of the product is ensured. Thus, an appropriate amount of citric acid is added to the formulation to ensure that the pH of the formulation is within a suitable range.
The preparation method of the crystalline amino acid facial cleanser comprises the following steps:
(1) Mixing glycerol, amino acid surfactant, crystallization regulator, citric acid and water, heating to 80deg.C;
(2) And uniformly dispersing the crystallizing agent in the system to obtain the crystalline amino acid facial cleanser.
The crystallized amino acid facial cleanser is coagulated at 40-50 ℃ and is discharged after being cooled to below 40 ℃.
The above materials and their names are mainly based on the catalogue of used cosmetics (2021 edition).
Compared with the prior art, the invention has the following beneficial effects:
according to the invention, from the perspective of crystals, the crystal size and the crystal form of the amino acid surfactant in an alcohol-water system under the acidic condition are adjusted by adding a proper amount of the crystallization agent and the crystallization regulator, so that the purposes of increasing the stability of paste and improving the appearance of the paste are achieved. The crystalline amino acid cleansing cream disclosed by the invention has the advantages of good stability and hardness, obvious pearl effect and excellent dissolution property. The addition amount of the additive in the crystalline amino acid cleansing cream is smaller, so that the influence of the additive on the product performance is smaller.
Drawings
FIG. 1 is a sample microscope image of example 1.
Fig. 2 is a microscopic image of the sample of comparative example 1.
Fig. 3 is a sample microscope image of comparative example 3.
FIG. 4 is a sample microscope image of comparative example 4.
FIG. 5 is a standard for the pearlescence evaluation of a facial cleanser; wherein, the pearlescence is changed from weak to strong in sequence from the serial numbers 1 to 5.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Examples 1 to 9 and comparative examples 1 to 6
The compositions of the crystalline amino acid cleansing creams of examples 1 to 9 and comparative examples 1 to 6 are shown in tables 1 and 2.
The preparation method of the crystalline amino acid cleansing cream of examples 1 to 9 is as follows:
s1, adding glycerol, potassium cocoyl glycinate (aqueous solution with the active matter content of 30wt percent), citric acid, water and a crystallization regulator into a reaction kettle, and heating while stirring to enable the system to be heated to 80 ℃, wherein the system is transparent liquid;
s2, adding a crystallizing agent (average particle size is 50 nm), starting stirring to uniformly disperse the crystallizing agent in the system, and then cooling to 40 ℃ to obtain the crystalline amino acid cleansing cream.
The crystalline amino acid cleansing creams of comparative examples 1 to 6 were prepared by a method different from examples 1 to 9 in that the steps related to the removal of the non-added components.
The pH of the final sample was measured by dilution method, test method: a 10% suspension of the sample was prepared and its pH was then determined. The final measurement of the pH of the samples of examples 1-9 and comparative examples 1-4 was around 6.5, the pH of comparative example 5 was 7.5, and the pH of comparative example 6 was 5.5.
TABLE 1 crystalline amino acid cleansing cream compositions of examples 1-9 (parts by weight)
Table 2 crystalline amino acid cleansing cream compositions (parts by weight) of comparative examples 1 to 6
Effect testing
Test 1. Stability, appearance and crystal particle size were measured for the samples of examples 1-9 and comparative examples 1-6.
1. The stability of the sample is evaluated by adopting four-week thermal stability experiments, and the experimental method comprises the following steps:
a certain amount of sample (25 g) is weighed into a sample bottle, the sample is placed in a constant temperature box at 45 ℃, and the conditions of layering, liquid separation, coarsening and the like are observed and recorded at intervals of time (1, 3, 7, 14, 21, 27 day). The recording results are shown in Table 3.
2. And judging the appearance quality of the product by observing the hardness and the pearly-lustre strength of the product. The judging method comprises the following steps:
placing the sample into a sample bottle, standing for one day, and judging the hardness and the pearly-lustre strength of the sample. Hardness was measured using SunRHEO METER CR-3000EX, and according to the sample shape, the invention uses a No. 25 jig. The pearl intensity was evaluated by the scoring method, wherein the pearl intensity of 1 minute was the weakest, the pearl intensity of 5 minutes was the strongest, and the pearl effect of 1 to 5 minutes was shown in FIG. 5, wherein the pearl intensity of 1 minute: no pearlescence; 2, the method comprises the following steps: slightly pearlescent; 3, the method comprises the following steps: obvious pearly luster, but the paste is whitened; 4, the following steps: has obvious pearl luster and slight pearl luster lines; 5, the method comprises the following steps: has obvious pearl luster and strong pearl luster lines. The recording results are shown in Table 4. Fig. 1 to 4 are optical microscopic images of the samples of example 1, comparative example 3, and comparative example 4, at 40 times magnification.
3. The medium particle diameter D50 of the sample was measured by a laser particle diameter meter, and the recording results are shown in table 4.
4. The paste temperature of the sample was measured by a thermometer, and the recording results are shown in table 4.
TABLE 3 Table 3
TABLE 4 Table 4
Test 2. Test the sample solubilities of examples 1-9 and comparative examples 1-6 were tested.
The solubility test is a test of the dispersion speed of the sample in water, illustrating the ability of the sample to push and rub water. The testing method comprises the following steps:
(1) 5g of the sample was weighed into a beaker and 15g of deionized water was then added.
(2) The mechanical stirring was started at a stirring speed of 100r/min and the time for complete dispersion of the sample was counted and the results are shown in Table 5.
TABLE 5
Finally, it should be noted that the above embodiments are only for illustrating the technical solution of the present invention and not for limiting the scope of the present invention, and although the present invention has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that the technical solution of the present invention may be modified or substituted equally without departing from the spirit and scope of the technical solution of the present invention.
Claims (3)
1. The crystalline amino acid cleansing cream is characterized by comprising the following components in parts by mass: 40 parts of glycerol, 12 parts of amino acid surfactant, 0.1-0.5 part of crystallization agent, 0.5-2 parts of crystallization regulator, 1-2 parts of citric acid and 15-20 parts of water;
the amino acid surfactant is potassium cocoyl glycinate and/or sodium cocoyl glycinate;
the crystallizing agent is nano-scale hydrated silica; the average grain diameter of the crystallization agent is 10-100nm;
the crystallization regulator is polyglycerol-10 myristate, stearyl citrate and laureth-6 sodium carboxylate, and the mass ratio is 30-50:30-50:0-20 proportion.
2. The crystalline amino acid cleansing cream according to claim 1, which is characterized by comprising the following components in parts by mass: 40 parts of glycerol, 12 parts of amino acid surfactant, 0.3 part of crystallization agent, 1 part of crystallization regulator, 1.6 parts of citric acid and 17-18 parts of water.
3. The method for preparing the crystalline amino acid cleansing cream according to any one of claims 1 to 2, comprising the steps of:
(1) Mixing glycerol, amino acid surfactant, crystallization regulator, citric acid and water, heating to 80deg.C;
(2) And uniformly dispersing the crystallizing agent in the system to obtain the crystalline amino acid facial cleanser.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202310292018.2A CN116392400B (en) | 2023-03-22 | 2023-03-22 | Crystalline amino acid facial cleanser and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310292018.2A CN116392400B (en) | 2023-03-22 | 2023-03-22 | Crystalline amino acid facial cleanser and preparation method thereof |
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| CN116392400B true CN116392400B (en) | 2024-03-08 |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107913191A (en) * | 2017-11-29 | 2018-04-17 | 诺斯贝尔化妆品股份有限公司 | A kind of more bubble crystal type amino acid cleansing creams |
| CN107997977A (en) * | 2017-12-04 | 2018-05-08 | 湖南金昌生物技术有限公司 | A kind of amino acid system face cleaning cream and preparation method thereof |
| CN110302099A (en) * | 2019-06-18 | 2019-10-08 | 广州艾蓓生物科技有限公司 | A kind of face cleaning cream and preparation method thereof |
| CN112842920A (en) * | 2019-11-12 | 2021-05-28 | 美特瑞生物科技(上海)有限公司 | Amino acid facial cleanser with liquid crystal structure |
| CN114177110A (en) * | 2021-12-16 | 2022-03-15 | 名臣健康用品股份有限公司 | High-stability pure amino acid facial cleansing cream and preparation method thereof |
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Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107913191A (en) * | 2017-11-29 | 2018-04-17 | 诺斯贝尔化妆品股份有限公司 | A kind of more bubble crystal type amino acid cleansing creams |
| CN107997977A (en) * | 2017-12-04 | 2018-05-08 | 湖南金昌生物技术有限公司 | A kind of amino acid system face cleaning cream and preparation method thereof |
| CN110302099A (en) * | 2019-06-18 | 2019-10-08 | 广州艾蓓生物科技有限公司 | A kind of face cleaning cream and preparation method thereof |
| CN112842920A (en) * | 2019-11-12 | 2021-05-28 | 美特瑞生物科技(上海)有限公司 | Amino acid facial cleanser with liquid crystal structure |
| CN114177110A (en) * | 2021-12-16 | 2022-03-15 | 名臣健康用品股份有限公司 | High-stability pure amino acid facial cleansing cream and preparation method thereof |
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| CN116392400A (en) | 2023-07-07 |
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