CN116350729A - Traditional Chinese medicine composition for treating epigastric pain and preparation method and application thereof - Google Patents

Traditional Chinese medicine composition for treating epigastric pain and preparation method and application thereof Download PDF

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CN116350729A
CN116350729A CN202310249558.2A CN202310249558A CN116350729A CN 116350729 A CN116350729 A CN 116350729A CN 202310249558 A CN202310249558 A CN 202310249558A CN 116350729 A CN116350729 A CN 116350729A
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parts
pain
traditional chinese
chinese medicine
root
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杨杰
王春莲
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Sichuan Sanhe Vocational College
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Sichuan Sanhe Vocational College
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    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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Abstract

The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a traditional Chinese medicine composition for treating epigastric pain, and a preparation method and application thereof, wherein the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 14-16 parts of bupleurum, 9-11 parts of white peony root, 9-11 parts of immature bitter orange, 9-11 parts of honey-fried licorice root, 9-11 parts of nutgrass galingale rhizome, 11-13 parts of rhizoma corydalis, 14-16 parts of costustoot, 29-31 parts of fructus amomi, 14-16 parts of poria cocos, 11-13 parts of dried orange peel, 9-11 parts of medicated leaven, 9-11 parts of fennel, wu Zhu-4 parts of root of three-nerved spicebush, 11-13 parts of fingered citron, 14-16 parts of galangal, 9-11 parts of bamboo shavings, 9-11 parts of Chinese yam, 39-41 parts of fried malt, 39-41 parts of fried rice sprout and 14-16 parts of dandelion. The invention has the effects of soothing liver, regulating qi, warming channels, dispelling cold, harmonizing stomach, relieving pain, strengthening spleen, harmonizing stomach, promoting digestion, and removing food stagnation, can be used for treating symptoms such as liver depression, qi stagnation, chest stuffiness, fullness and distention, gastralgia and the like, and has good pain relieving effect.

Description

Traditional Chinese medicine composition for treating epigastric pain and preparation method and application thereof
Technical Field
The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a traditional Chinese medicine composition for treating epigastric pain, and a preparation method and application thereof.
Background
Epigastric pain symptoms occur in many diseases, causing great pain to patients and even affecting work, learning and daily life. Stomach diseases are common in clinic, stomach diseases are difficult to treat, deficiency and excess are easy to occur, and recovery is difficult to occur, and the stomach diseases are also recognized by doctors. If the patient is uncomfortable with cold, heat and cool, the patient should not take care of diet and not feel depressed, and the law of yin and yang should not be regulated, the occurrence of stomach diseases will be caused. For example, in rural areas, about one third of patients routinely visit local rural doctors because of symptoms in terms of stomach illness. Statistics of data show that the incidence rate of peptic ulcer diseases, acute and chronic gastritis in people is as high as 18.5% in the categories of epigastric pain, stomach-packing, gastric fullness and the like in traditional Chinese medicine; the incidence of other gastric disorders, such as bloating, regurgitation, vomiting and retching, is higher. Nearly 20 ten thousand new stomach cancers are estimated in China every year, accounting for 17.2% of the incidence rate of all malignant tumors, and are the first place.
At present, when epigastric pain is encountered in clinic, the common western medicine analgesic has dependence and tolerance and other side effects. The traditional Chinese medicine has small side effects, and related reports exist in the prior art, but in general, when the traditional Chinese medicine is used for treating epigastric pain, the treatment course is long, the cure rate is low, and the pain is easy to repeat. This is because most traditional Chinese medicines do not have strict analysis on the etiology and pathogenesis of epigastric pain and treat the epigastric pain in a targeted way, so that the epigastric pain is not cured fundamentally. Therefore, the invention provides a traditional Chinese medicine composition for treating epigastric pain.
Disclosure of Invention
In order to solve the technical problems, the invention provides a traditional Chinese medicine composition for treating epigastric pain, and a preparation method and application thereof. The invention provides a medicine which has better pain relieving effect and can treat acute and chronic epigastric pain caused by chronic superficial gastritis, gastric hyperacidity, gastric ulcer, atrophic gastritis, flaming, erosive gastritis and the like, and particularly can obviously improve clinical symptoms of pain, distention, sleepiness, anger, noisy and sour.
The invention is realized by the following technical scheme.
The invention provides a traditional Chinese medicine composition for treating epigastric pain, which comprises the following raw materials in parts by weight: 14-16 parts of bupleurum, 9-11 parts of white peony root, 9-11 parts of immature bitter orange, 9-11 parts of honey-fried licorice root, 9-11 parts of nutgrass galingale rhizome, 11-13 parts of rhizoma corydalis, 14-16 parts of costustoot, 29-31 parts of fructus amomi, 14-16 parts of poria cocos, 11-13 parts of dried orange peel, 9-11 parts of medicated leaven, 9-11 parts of fennel, wu Zhu-4 parts of root of three-nerved spicebush, 11-13 parts of fingered citron, 14-16 parts of galangal, 9-11 parts of bamboo shavings, 9-11 parts of Chinese yam, 39-41 parts of each of stir-fried two buds (malt and rice sprout) and 14-16 parts of dandelion.
Preferably, the material comprises the following raw materials in parts by weight: 15 parts of radix bupleuri, 10 parts of white peony root, 10 parts of immature bitter orange, 10 parts of honey-fried licorice root, 10 parts of nutgrass galingale rhizome, 12 parts of rhizoma corydalis, 15 parts of costustoot, 30 parts of fructus amomi, 15 parts of poria cocos, 12 parts of dried orange peel, 10 parts of medicated leaven, 10 parts of fennel, parts of evodia rutaecarpa, 12 parts of lindera root, 10 parts of fingered citron, 15 parts of galangal, 10 parts of bamboo shavings, 10 parts of Chinese yam, 40 parts of stir-fried two buds respectively and 15 parts of dandelion.
Preferably, the dosage form of the traditional Chinese medicine composition comprises decoction, powder, medicinal granules, oral liquid or tablets.
Preferably, the Chinese medicinal composition is prepared into decoction (named Jielian Chaishao and stomach pain relieving decoction), and the preparation method comprises the following steps of:
the following raw materials in parts by weight are respectively weighed: 14-16 parts of radix bupleuri, 9-11 parts of white peony root, 9-11 parts of immature bitter orange, 9-11 parts of honey-fried licorice root, 9-11 parts of nutgrass galingale rhizome, 11-13 parts of rhizoma corydalis, 14-16 parts of costustoot, 29-31 parts of fructus amomi, 14-16 parts of poria cocos, 11-13 parts of dried orange peel, 9-11 parts of medicated leaven, 9-11 parts of fennel, wu Zhu-4 parts of radix linderae, 11-13 parts of lindera root, 9-11 parts of fingered citron, 14-16 parts of galangal, 9-11 parts of bamboo shavings, 9-11 parts of Chinese yam, 39-41 parts of stir-fried two buds and 14-16 parts of dandelion;
soaking the above materials in water, decocting, boiling with strong fire, decocting with slow fire, and filtering.
Preferably, water is added to 5 minutes beyond the surface of the medicinal material.
Preferably, the soaking time is 25-35min.
Preferably, boiling with strong fire for 9-11min, and decocting with slow fire for 4-6 min.
The invention also provides application of the traditional Chinese medicine composition in preparing medicines for treating epigastric pain.
The efficacy of each component in the traditional Chinese medicine composition is as follows:
chai Hu is slightly cold in nature and bitter in taste. It enters liver meridian, gallbladder meridian and lung meridian. Relieving exterior and interior syndrome, soothing liver, and elevating yang. Belongs to the pungent and cool exterior-releasing herbs of the category of exterior-releasing herbs.
Bai Shao is slightly cold in nature, bitter in flavor and sour. Enter liver meridian and spleen meridian. Pacify liver, alleviate pain, nourish blood, regulate menstruation, astringe yin and stop sweating. Belongs to the blood-replenishing herbs belonging to the category of the deficiency-tonifying herbs.
Zhi Shi is slightly cold in nature, bitter, pungent and sour in flavor. Enter spleen meridian and stomach meridian. Break qi, remove food retention, resolve phlegm and resolve distension and fullness. Belongs to a qi-regulating medicine.
Roasted licorice root, radix Glycyrrhizae Praeparata, is warm in nature and sweet in taste. It enters heart meridian, lung meridian, stomach meridian and spleen meridian. Tonify spleen and stomach, replenish qi and recover pulse. Belongs to qi-tonifying herbs classified under deficiency-tonifying herbs.
Nutgrass galingale rhizome, rhizoma Cyperi, has flat nature, pungent, slightly bitter and slightly sweet. Enter liver meridian and triple energizer meridian. Promoting qi circulation, resolving stagnation, regulating menstruation and relieving pain. Belongs to a qi-regulating medicine.
The corydalis tuber is pungent in nature and enters liver meridian and spleen meridian. Promoting blood circulation, removing blood stasis, regulating qi and relieving pain.
Mu Xiang is warm in nature and pungent in flavor and bitter in flavor. It enters spleen meridian, stomach meridian, large intestine meridian, triple energizer meridian and gallbladder meridian. Promoting qi circulation, relieving pain, invigorating spleen, and resolving food stagnation. Belongs to a qi-regulating medicine.
Sha ren is warm in nature and pungent in flavor. Enter stomach meridian, spleen meridian and kidney meridian. Resolving dampness, stimulating appetite, warming spleen, relieving diarrhea, regulating qi-flowing, and preventing miscarriage. Belongs to a damp-resolving medicine.
Poria cocos is neutral in nature and sweet and light in taste. It enters heart meridian, lung meridian, spleen meridian and kidney meridian. Induce diuresis and excrete dampness, invigorate spleen and calm heart. Belongs to the classified diuretics and detumescence herbs under the action of diuresis and dampness-removing herbs.
Chen Pi is pungent in flavor, bitter in flavor and warm in nature. Enter spleen meridian and lung meridian. Regulating qi-flowing, stimulating appetite, eliminating dampness and resolving phlegm, and treating spleen and stomach diseases. Belongs to a qi-regulating medicine.
Massa Medicata Fermentata is sweet and pungent in taste and warm in nature. Enter spleen and stomach meridians. Has effects in invigorating spleen, regulating stomach function, promoting digestion, and removing food retention. Can be used for treating food stagnation, dyspepsia, abdominal distention, inappetence, emesis, and dysentery.
Fennel, fructus Foeniculi, having effects of dispelling cold and relieving pain, regulating qi and harmonizing stomach.
Wu Zhu it has effects of dispersing stagnated liver qi, descending qi, warming spleen, relieving diarrhea, dispelling cold, and relieving pain.
Lindera root, radix Linderae, with warm nature and pungent taste. It enters lung meridian, spleen meridian, kidney meridian and bladder meridian. Promoting qi circulation, resolving stagnation, dispelling cold, and relieving pain. Belongs to a qi-regulating medicine.
Fingered citron is warm in nature, pungent, bitter and sour in flavor. Enter lung meridian, spleen meridian and liver meridian. Soothing liver, regulating qi, regulating stomach function and relieving pain. Belongs to a qi-regulating medicine.
Galangal, it is hot in nature and pungent in flavor. Enter spleen meridian and stomach meridian. Warming stomach, relieving vomiting, dispelling cold and relieving pain. Belongs to the interior warming herb.
Bamboo shavings are slightly cold in nature and sweet in taste. Enter stomach meridian, gallbladder meridian and spleen meridian. Clear heat and resolve phlegm, relieve dysphoria and arrest vomiting. Belongs to the heat-clearing and phlegm-resolving herbs in the category of phlegm-resolving, cough-relieving and asthma-relieving herbs.
Chinese yam, rhizoma dioscoreae, capable of tonifying spleen and stomach, promoting fluid production and tonifying lung, and tonifying kidney and astringing essence.
Dandelion is bitter and sweet in flavor, cold in nature, enters liver meridian and stomach meridian, and has the effects of clearing heat and detoxicating, promoting urination and resolving masses, diminishing inflammation and sterilizing.
Parching two buds, and invigorating spleen with fructus Hordei Germinatus, and stomach with cereal buds; malt is mainly raised, rice sprout is mainly lowered, and the two medicines are combined together, so that the spleen and stomach are harmonized, and the appetite and the spleen are improved.
Epigastric pain, also known as gastralgia, is a condition where pain in the proximal fossa of the epigastric region is the main symptom. The name of "epigastric pain" is recorded in the book of internal menstruation at the earliest time, such as "the form of Ling-Pi, pathogenic qi and zang-fu organs" in the cloud. And first proposes that the occurrence of stomach ache is related to liver and spleen, as described in the "Su-Liuyuan zhengji university: wood Yu Fa, the people's disease is pain with the stomach being careful. In clinic, the pain of epigastric pain is caused by depression, liver injury, liver failure, and diarrhea, and the pain is caused by incoordination between the liver and stomach, qi stagnation. It is indicated for depression with liver-qi dispersing and qi-flowing regulating and pain-relieving effects. For example, ming Dynasty Zhang Jiebin, written in Jingyue quan Shu, describes "epigastric pain syndrome, which is mainly caused by food, qi disorder, qi stagnation due to food cold, qi stagnation due to food retention, and qi stagnation due to cold retention. Therefore, it is mainly indicated for pain due to qi-flowing. Therefore, the treatment of epigastric pain can be achieved only by soothing liver, regulating qi, harmonizing stomach and relieving pain and other methods.
According to the analysis of etiology and pathogenesis and treatment method of the epigastric pain, the Jielian Chashao stomach-harmonizing pain-relieving decoction accords with the rule of treating the epigastric pain, and has the effects of soothing liver-qi stagnation, regulating qi and harmonizing stomach to relieve pain. The vinegar-processed bupleurum root, white peony root, honey-fried licorice root, immature bitter orange and fingered citron are the common medicine groups for regulating qi and harmonizing the stomach for the pencils, are the monarch drugs for the pencils, and are the five drugs for mutual compatibility, qi and blood double-regulation, qi and blood regulation, qi-regulating and phlegm-resolving, vomiting-relieving and distention-relieving, liver-soothing and spleen-strengthening, stomach-harmonizing and pain-relieving, liver-soothing and depression-relieving functions. Paeonia lactiflora and licorice root, radix Paeoniae and licorice root, radix Glycyrrhizae Praeparata, acid and sweet in nature, can dispel yin, harmonize yin and yang blood, relieve spasm and pain to calm the middle warmer; rhizoma Cyperi into liver, regulating qi and regulating blood, rhizoma corydalis, radix aucklandiae, regulating qi and relieving pain, invigorating spleen and resolving food stagnation; fructus Amomi has effects of warming spleen, stimulating appetite, eliminating dampness and activating qi-flowing; the medicines are ministerial medicines in the prescription, and are auxiliary medicines for harmonizing stomach, strengthening spleen, promoting qi and relieving pain. Poria, pericarpium Citri Tangerinae, massa Medicata Fermentata for invigorating spleen, eliminating dampness, regulating qi-flowing, invigorating spleen, eliminating dampness, resolving phlegm, resolving food stagnation, and regulating stomach; fennel, wu Zhu, combined spicebush root and galangal rhizome have the functions of warming stomach and relieving pain, warming channel and dispelling cold, and assisting the monarch drugs in harmonizing stomach and strengthening spleen, and activating qi-flowing and relieving pain; caulis Bambusae in Taenia, has effects of clearing heat, relieving restlessness, regulating stomach function, and relieving vomiting; chinese yam has the effects of strengthening spleen and stomach, and helping transportation and increasing food; the dandelion enters the liver and stomach channels, clears away heat and toxic materials and relieves pain, and the modern pharmacological research has the effects of killing and inhibiting helicobacter pylori and repairing the damage of gastric mucosa; the coptis root has the functions of clearing heat and relieving restlessness, wu Zhu has the functions of warming the stomach and relieving pain, and the thirteen medicines are used as auxiliary medicines in the prescription and assist the force of monarch medicines in the prescription. Stir-baked two buds are the main drugs of spleen and stomach because they are the herbs in the recipe, have mild nature and taste, develop spleen and stomach without rising to hurt yin, and "two buds develop stomach qi, xuan Wugu, miao Zhongchun cloud, two buds have biochemical property". "malt supplements spleen, and cereal sprouts enter stomach; the malt is mainly lifted, the rice sprout is mainly lowered, and the two medicines are combined, so that the spleen and stomach are harmonized, the appetite is enhanced, the spleen is enhanced, the appetite is enhanced, the lifting is orderly, the two medicines are 40g each with larger dosage, so that the qi movement is more active, the medicine efficacy can be carried, the medicine efficacy can be better exerted, and the effect of the medicine is better achieved. The medicines are combined together to have the unique effects of strengthening spleen and stomach, regulating qi and relieving pain, so that the medicine can achieve better curative effect on epigastric pain.
The Jielian Chashao decoction for regulating stomach and relieving pain is clinically applied, has satisfactory curative effect, is a good prescription for treating acute and chronic epigastric pain caused by chronic superficial gastritis, gastric hyperacidity, gastric ulcer, atrophic gastritis, flaming, erosive gastritis and the like, and can obviously improve the clinical symptoms of pain, distention, anger, gastric upset, acid and the like. If pantothenic acid is regurgitated and the mouth water is removed, zuojin pill is added to remove liver heat and resolve depression to prepare acid, cuttlefish bone is added to warm and sour to promote blood circulation, corrugated son is added to salty and remove blood and to soften hardness and dissipate stagnation to relieve pain and stop pantothenic acid. If the patient suffers from the chronic gastric disease or stasis, the medicine is matched with the self-made stomach-harmonizing powder for use: 50g of cuttlefish bone, 50g of aspongopus, 50g of hedgehog skin and 50g of cardamom, wherein the total fine powder is 10g each time, 3 times a day, and the mixture is taken after being mixed with honey.
The common telephone says that the stomach diseases are "the three-way treatment and the seven-way treatment" and the good prescription for treating stomach diseases is "the treatment" and the urgent need is not. We all need a good stomach and some bad habits have to be changed. The stomach disease is nourished again: i.e. those suffering from stomach diseases, care should be taken to keep the stomach warm in order to prevent the stomach from getting cold and causing gastralgia or aggravating old diseases. The stomach disease patients should take warm, soft, light, plain and fresh foods to achieve timing and quantitative effects, and take many meals to neutralize the stomach with food and gastric acid, thereby preventing erosion of gastric mucosa and ulcer surface and aggravating illness. Expert students consider that the occurrence and development of gastric diseases are closely related to the emotion of people, so that optimistic emotion is kept, and the stimulation of bad emotion such as tension, anxiety, anger and the like is avoided. Meanwhile, the combination of overstrain and overstrain is preferable to avoid the damage of spleen and stomach. The people suffering from stomach illness need to combine the physical signs of the people, strengthen moderate exercise, improve the disease resistance of the organism, reduce the recurrence of the disease and promote physical and mental health.
Compared with the prior art, the invention has the following beneficial effects:
1. the invention carries out deep analysis on etiology and pathogenesis of epigastric pain and a treatment method, has reasonable compatibility, combines the medicines, has the effects of soothing liver and regulating qi, warming channels and dispelling cold, harmonizing stomach and relieving pain, strengthening spleen and stomach, and promoting digestion and removing stagnation, can treat acute and chronic epigastric pain caused by chronic superficial gastritis, gastric hyperacidity, gastric ulcer, atrophic gastritis, flaming, erosive gastritis and the like, can obviously improve clinical symptoms such as pain, distention, sleepiness, anger, noisy, acid and the like, has better pain relieving effect, quick curative effect and wide pain relieving range.
2. The traditional Chinese medicine composition provided by the invention has the advantages of short treatment course, good treatment effect and no repetition; the preparation method is simple, and can be completely suitable for treating epigastric pain.
Detailed Description
In order that those skilled in the art will better understand the technical scheme of the present invention, the present invention will be further described with reference to specific examples and data, but the examples are not intended to limit the present invention.
Example 1
A Chinese medicinal composition for treating epigastric pain comprises the following raw materials: 15g of bupleurum, 10g of white peony root, 10g of immature bitter orange, 10g of honey-fried licorice root, 10g of nutgrass galingale rhizome, 12g of rhizoma corydalis, 15g of costustoot, 30g of fructus amomi, 15g of poria cocos, 12g of dried orange peel, 10g of medicated leaven, 10g of fennel, wu Zhu g of root of three-nerved spicebush, 10g of fingered citron, 15g of galangal, 10g of bamboo shavings, 10g of Chinese yam, 40g of fried two buds respectively and 15g of dandelion.
The Chinese medicinal composition for treating the epigastric pain is prepared into decoction, and the specific preparation method comprises the following steps of:
the traditional Chinese medicine composition is placed in a marmite, cold water is added to immerse the medicinal materials, the water surface exceeds 5 minutes, the medicinal materials are placed on fire for decoction after being soaked for 30 minutes, the medicinal materials are boiled for 10 minutes by strong fire, and then the medicinal materials are boiled by slow fire for 5 minutes, so that the traditional Chinese medicine composition is not suitable for long-term decoction.
The administration method comprises the following steps:
about 200 milliliters of the filtered medicine juice is taken each time, 1 dose/2 d,3 times/d and 15d are 1 course of treatment. When the Jielian Chashao decoction for regulating stomach and relieving pain is taken, the Jielian Chashao decoction is taken, a plurality of foods are needed, the food is taken as light food, and binge eating is avoided. The food such as barbecue and the like is to be stopped from eating spicy, fried and smoked foods, the food with strong stimulation such as peracid, supercooling and the like is not to be eaten, the drinking is not to be drunk, the eating of thick tea and the like is avoided as much as possible, and the food such as vegetable and the like is to be eaten. The administration should be carried out after meals to prevent the disease from deteriorating due to irritation of gastric mucosa.
Example 2
A Chinese medicinal composition for treating epigastric pain comprises the following raw materials: 16g of bupleurum, 9g of white peony root, 11g of immature bitter orange, 9g of honey-fried licorice root, 11g of nutgrass galingale rhizome, 11g of rhizoma corydalis, 14g of costustoot, 29g of fructus amomi, 14g of poria cocos, 11g of dried orange peel, 11g of medicated leaven, 9g of fennel, wu Zhu g of root of three-nerved spicebush, 9g of fingered citron, 16g of galangal, 11g of bamboo shavings, 9g of Chinese yam, 40g of fried two buds respectively and 14g of dandelion.
The Chinese medicinal composition for treating the epigastric pain is prepared into decoction, and the specific preparation method comprises the following steps of:
the traditional Chinese medicine composition is placed in a marmite, cold water is added to immerse the medicinal materials, the water surface exceeds 5 minutes, the medicinal materials are placed on fire for decoction after being soaked for 30 minutes, the medicinal materials are boiled for 10 minutes by strong fire, and then the medicinal materials are boiled by slow fire for 5 minutes, so that the traditional Chinese medicine composition is not suitable for long-term decoction.
The administration method comprises the following steps:
about 200 milliliters of the filtered medicine juice is taken each time, 1 dose/2 d,3 times/d and 15d are 1 course of treatment. When the Jielian Chashao decoction for regulating stomach and relieving pain is taken, the Jielian Chashao decoction is taken, a plurality of foods are needed, the food is taken as light food, and binge eating is avoided. The food such as barbecue and the like is to be stopped from eating spicy, fried and smoked foods, the food with strong stimulation such as peracid, supercooling and the like is not to be eaten, the drinking is not to be drunk, the eating of thick tea and the like is avoided as much as possible, and the food such as vegetable and the like is to be eaten. The administration should be carried out after meals to prevent the disease from deteriorating due to irritation of gastric mucosa.
Example 3
A Chinese medicinal composition for treating epigastric pain comprises the following raw materials: 14g of bupleurum, 11g of white peony root, 9g of immature bitter orange, 11g of honey-fried licorice root, 9g of nutgrass galingale rhizome, 13g of rhizoma corydalis, 16g of costustoot, 31g of fructus amomi, 16g of poria cocos, 13g of dried orange peel, 9g of medicated leaven, 11g of fennel, wu Zhu g of root of three-nerved spicebush, 11g of fingered citron, 14g of galangal, 9g of bamboo shavings, 11g of Chinese yam, 40g of fried two buds respectively and 16g of dandelion.
The Chinese medicinal composition for treating the epigastric pain is prepared into decoction, and the specific preparation method comprises the following steps of:
the traditional Chinese medicine composition is placed in a marmite, cold water is added to immerse the medicinal materials, the water surface exceeds 5 minutes, the medicinal materials are placed on fire for decoction after being soaked for 30 minutes, the medicinal materials are boiled for 10 minutes by strong fire, and then the medicinal materials are boiled by slow fire for 5 minutes, so that the traditional Chinese medicine composition is not suitable for long-term decoction.
The administration method comprises the following steps:
about 200 milliliters of the filtered medicine juice is taken each time, 1 dose/2 d,3 times/d and 15d are 1 course of treatment. When the Jielian Chashao decoction for regulating stomach and relieving pain is taken, the Jielian Chashao decoction is taken, a plurality of foods are needed, the food is taken as light food, and binge eating is avoided. The food such as barbecue and the like is to be stopped from eating spicy, fried and smoked foods, the food with strong stimulation such as peracid, supercooling and the like is not to be eaten, the drinking is not to be drunk, the eating of thick tea and the like is avoided as much as possible, and the food such as vegetable and the like is to be eaten. The administration should be carried out after meals to prevent the disease from deteriorating due to irritation of gastric mucosa.
Example 4
A Chinese medicinal composition for treating epigastric pain comprises the following raw materials: 15g of bupleurum, 9g of white peony root, 11g of immature bitter orange, 9g of honey-fried licorice root, 11g of nutgrass galingale rhizome, 11g of rhizoma corydalis, 16g of costustoot, 29g of fructus amomi, 15g of poria cocos, 11g of dried orange peel, 9g of medicated leaven, 9g of fennel, wu Zhu g of root of three-nerved spicebush, 9g of fingered citron, 16g of galangal, 11g of bamboo shavings, 9g of Chinese yam, 40g of fried two buds respectively and 14g of dandelion.
The Chinese medicinal composition for treating the epigastric pain is prepared into decoction, and the specific preparation method comprises the following steps of:
the traditional Chinese medicine composition is placed in a marmite, cold water is added to immerse the medicinal materials, the water surface exceeds 5 minutes, the medicinal materials are placed on fire for decoction after being soaked for 30 minutes, the medicinal materials are boiled for 10 minutes by strong fire, and then the medicinal materials are boiled by slow fire for 5 minutes, so that the traditional Chinese medicine composition is not suitable for long-term decoction.
The administration method comprises the following steps:
about 200 milliliters of the filtered medicine juice is taken each time, 1 dose/2 d,3 times/d and 15d are 1 course of treatment. When the Jielian Chashao decoction for regulating stomach and relieving pain is taken, the Jielian Chashao decoction is taken, a plurality of foods are needed, the food is taken as light food, and binge eating is avoided. The food such as barbecue and the like is to be stopped from eating spicy, fried and smoked foods, the food with strong stimulation such as peracid, supercooling and the like is not to be eaten, the drinking is not to be drunk, the eating of thick tea and the like is avoided as much as possible, and the food such as vegetable and the like is to be eaten. The administration should be carried out after meals to prevent the disease from deteriorating due to irritation of gastric mucosa.
Example 5
A Chinese medicinal composition for treating epigastric pain comprises the following raw materials: 16g of bupleurum, 10g of white peony root, 9g of immature bitter orange, 9g of honey-fried licorice root, 11g of nutgrass galingale rhizome, 13g of rhizoma corydalis, 14g of costustoot, 29g of fructus amomi, 14g of poria cocos, 11g of dried orange peel, 11g of medicated leaven, 9g of fennel, wu Zhu g of root of three-nerved spicebush, 9g of fingered citron, 16g of galangal, 10g of bamboo shavings, 9g of Chinese yam, 41g of fried two buds respectively and 16g of dandelion.
The Chinese medicinal composition for treating the epigastric pain is prepared into decoction, and the specific preparation method comprises the following steps of:
the traditional Chinese medicine composition is placed in a marmite, cold water is added to immerse the medicinal materials, the water surface exceeds 5 minutes, the medicinal materials are placed on fire for decoction after being soaked for 30 minutes, the medicinal materials are boiled for 10 minutes by strong fire, and then the medicinal materials are boiled by slow fire for 5 minutes, so that the traditional Chinese medicine composition is not suitable for long-term decoction.
The administration method comprises the following steps:
about 200 milliliters of the filtered medicine juice is taken each time, 1 dose/2 d,3 times/d and 15d are 1 course of treatment. When the Jielian Chashao decoction for regulating stomach and relieving pain is taken, the Jielian Chashao decoction is taken, a plurality of foods are needed, the food is taken as light food, and binge eating is avoided. The food such as barbecue and the like is to be stopped from eating spicy, fried and smoked foods, the food with strong stimulation such as peracid, supercooling and the like is not to be eaten, the drinking is not to be drunk, the eating of thick tea and the like is avoided as much as possible, and the food such as vegetable and the like is to be eaten. The administration should be carried out after meals to prevent the disease from deteriorating due to irritation of gastric mucosa.
Example 6
A Chinese medicinal composition for treating epigastric pain comprises the following raw materials: 15g of bupleurum, 9g of white peony root, 10g of immature bitter orange, 9g of honey-fried licorice root, 10g of nutgrass galingale rhizome, 11g of rhizoma corydalis, 14g of costustoot, 29g of fructus amomi, 14g of poria cocos, 13g of dried orange peel, 11g of medicated leaven, 10g of fennel, wu Zhu g of fennel, 11g of combined spicebush root, 9g of fingered citron, 16g of galangal, 11g of bamboo shavings, 9g of Chinese yam, 40g of fried two buds respectively and 15g of dandelion.
The Chinese medicinal composition for treating the epigastric pain is prepared into decoction, and the specific preparation method comprises the following steps of:
the traditional Chinese medicine composition is placed in a marmite, cold water is added to immerse the medicinal materials, the water surface exceeds 5 minutes, the medicinal materials are placed on fire for decoction after being soaked for 30 minutes, the medicinal materials are boiled for 10 minutes by strong fire, and then the medicinal materials are boiled by slow fire for 5 minutes, so that the traditional Chinese medicine composition is not suitable for long-term decoction.
The administration method comprises the following steps:
about 200 milliliters of the filtered medicine juice is taken each time, 1 dose/2 d,3 times/d and 15d are 1 course of treatment. When the Jielian Chashao decoction for regulating stomach and relieving pain is taken, the Jielian Chashao decoction is taken, a plurality of foods are needed, the food is taken as light food, and binge eating is avoided. The food such as barbecue and the like is to be stopped from eating spicy, fried and smoked foods, the food with strong stimulation such as peracid, supercooling and the like is not to be eaten, the drinking is not to be drunk, the eating of thick tea and the like is avoided as much as possible, and the food such as vegetable and the like is to be eaten. The administration should be carried out after meals to prevent the disease from deteriorating due to irritation of gastric mucosa.
Example 7
A Chinese medicinal composition for treating epigastric pain comprises the following raw materials: 15g of bupleurum, 9g of white peony root, 10g of immature bitter orange, 11g of honey-fried licorice root, 11g of nutgrass galingale rhizome, 11g of rhizoma corydalis, 15g of costustoot, 29g of fructus amomi, 14g of poria cocos, 11g of dried orange peel, 10g of medicated leaven, 9g of fennel, wu Zhu g of root of three-nerved spicebush, 10g of fingered citron, 16g of galangal, 11g of bamboo shavings, 11g of Chinese yam, 40g of fried two buds respectively and 14g of dandelion.
The Chinese medicinal composition for treating the epigastric pain is prepared into decoction, and the specific preparation method comprises the following steps of:
the traditional Chinese medicine composition is placed in a marmite, cold water is added to immerse the medicinal materials, the water surface exceeds 5 minutes, the medicinal materials are placed on fire for decoction after being soaked for 30 minutes, the medicinal materials are boiled for 10 minutes by strong fire, and then the medicinal materials are boiled by slow fire for 5 minutes, so that the traditional Chinese medicine composition is not suitable for long-term decoction.
The administration method comprises the following steps:
about 200 milliliters of the filtered medicine juice is taken each time, 1 dose/2 d,3 times/d and 15d are 1 course of treatment. When the Jielian Chashao decoction for regulating stomach and relieving pain is taken, the Jielian Chashao decoction is taken, a plurality of foods are needed, the food is taken as light food, and binge eating is avoided. The food such as barbecue and the like is to be stopped from eating spicy, fried and smoked foods, the food with strong stimulation such as peracid, supercooling and the like is not to be eaten, the drinking is not to be drunk, the eating of thick tea and the like is avoided as much as possible, and the food such as vegetable and the like is to be eaten. The administration should be carried out after meals to prevent the disease from deteriorating due to irritation of gastric mucosa.
The traditional Chinese medicine composition provided by the invention is evaluated by clinical treatment effect.
1 clinical manifestations and methods
1.1 clinically manifested as pain in the epigastric and epigastric region near the heart fossa, inappetence, eructation and acid regurgitation, pale tongue with white and greasy coating, wiry and slippery pulse.
1.2 diagnostic criteria the 1 st edition diagnostic criteria of the teaching material of national higher Chinese medicine university, chinese medicine science, is adopted:
(1) Pain in the epigastric area is often accompanied by inappetence, stuffiness and fullness, nausea and vomiting, acid regurgitation and gastric upset.
(2) The onset is often related to emotional disturbance, improper diet, fatigue, cold-attack and other factors.
(3) A history of onset, or urgency or slowness, recurrent episodes.
(4) The X-ray barium meal photography of the upper digestive tract, the fibergastroscope, the pathological histology examination and the like are helpful for diagnosis.
1.3A Chinese medicinal composition Jielian Chashao stomach-regulating pain-relieving decoction for treating acute and chronic epigastralgia caused by chronic superficial gastritis, gastric hyperacidity, gastric ulcer, atrophic gastritis, flaming, erosive gastritis, etc., especially for obviously improving clinical symptoms of pain, distention, anger, gastric upset and acid, and its preparation method and use.
The Jielian Chashao stomach-harmonizing pain-relieving decoction consists of 15g of bupleurum, 10g of white peony root, 10g of immature bitter orange, 10g of honey-fried licorice root, 10g of nutgrass galingale rhizome, 12g of rhizoma corydalis, 15g of costustoot, 30g of fructus amomi, 15g of poria cocos, 12g of dried orange peel, 10g of medicated leaven, 10g of fennel, wu Zhu g of combined spicebush root, 10g of fingered citron, 15g of galangal, 10g of bamboo shavings, 10g of Chinese yam, 40g of each of stir-fried two buds and 15g of dandelion.
The traditional Chinese medicine composition is placed in a marmite, cold water is added to immerse the medicinal materials, the water surface exceeds 5 minutes, the medicinal materials are placed on fire for decoction after being soaked for 30 minutes, the medicinal materials are boiled for 10 minutes by strong fire, and then the medicinal materials are boiled by slow fire for 5 minutes, so that the medicinal materials are not suitable for long-term decoction.
About 200 milliliters of the filtered medicine juice is taken each time, 1 dose/2 d,3 times/d and 15d are 1 course of treatment.
Add-subtract with syndrome:
(1) For people with wet spleen and stomach sleepiness, 15g of wrinkled giant hyssop and 15g of herb of nodding off the head are added.
(2) Semen Trichosanthis 12g or semen Scaphii Lychnophori 12g, folium sennae 10g, faeces Bombycis 12g, herba cistanches 12g, caulis Perillae 10g, natrii sulfas 10g can be added for constipation patients to replace tea with water, so as to relieve the symptoms of drinking.
(3) For vomiting due to adverse stomach reaction, 10g of ginger processed pinellia tuber is added.
(4) For those with pantothenic acid and clear water, 20g of cuttlefish bone is added.
(5) The diarrhea patients with excessive dampness is treated by soaking 30g (broken) of cardamom in water instead of tea, and the diarrhea patients are treated by drinking.
(6) For patients with tenesmus, radix astragali 40g and cimicifugae rhizoma 10g are added.
(7) For insomnia patients, 10g of tuber fleeceflower stem and 10g of cortex albiziae are added.
(8) Jin Najin 30g for anorexia.
(9) Pollen 15g is added for the patient with fluid wound thirst.
(10) Fructus Aurantii 12g may be added for patients with severe abdominal distention.
(11) For people with indigestion and qi stagnation, 20g of puer tea is added, and modern pharmacological research shows that caffeine and flavanol compounds in puer tea can enhance the peristalsis of the digestive tract, thereby being beneficial to the digestion of food.
(12) For gastric mucosa congestion, edema, even erosion, ulcer (caused by long-term pathogenic heat and stomach injury), fructus forsythiae 30g and flos Lonicerae 20g can be added.
(13) For severe singultus, 15g of calyx kaki is added.
(14) For ulcer hemorrhage, 15g of rhizoma bletillae, 9g of pseudo-ginseng powder (taken with water) and 10g of hairyvein agrimony are added for patients with black stool like cypress oil.
During the taking of the recipe, the diet is suitable for feeding fluid or semi-fluid, is easy to digest, and is suitable for a small number of foods; coarse multi-fiber diet is avoided, and strong tea, coffee and spicy food are avoided as much as possible; the food is suitable for chewing the throat, and simultaneously keeps optimistic emotion, and is suitable for combining overstrain and overstrain, so that the spleen and stomach are prevented from being damaged by overstrain and overstrain.
The Jielian Chashao Jiwei Zhitong decoction of the invention treats 152 cases (112 cases of men, 40 cases of women, age 15-55 years old, 131 cases of 16-35 years old, 12-25 d of disease course, 152 cases are accompanied by unsmooth emotion, the patients are mainly suffering from pain at the position of the epigastric fossa near the abdomen, inappetence, eructation, acid regurgitation, pale tongue with white greasy coating, wiry and slippery pulse and other diseases), 128 cases are cured, 5 cases are obvious, 7 cases are effective, 12 cases are ineffective, the total effective rate is 92.10%, the following observation is carried out for more than 3 months after the treatment of the total effective cases, no adverse reaction occurs, and the decoction is worthy of clinical popularization and application and further research.
2 typical cases
2.1 Jiang Mou, female, 12 years old, student. The patients have pain in the epigastrium and the abdomen caused by improper diet for 4 years, but the patients have mild and severe illness state through traditional Chinese and western medicine treatment (detailed diagnosis and treatment) for 3 years, and symptoms are aggravated when the patients are improper for diet and emotional disturbance. At a certain hospital, the chronic superficial gastritis and the slight duodenal ulcer are diagnosed by gastroscopy. 5 days ago, after the patient and the students are over-angry, the pain of the gastric cavity is aggravated, and the patient asks the pen for diagnosis and treatment. The symptoms are paroxysmal severe pain, vomit, bitter and water, severe fasting pain, vexation and irritability, frequent belch, chest distress and excessive breath, frequent retching in the early morning, anorexia, tiredness and hypodynamia, sleepiness, nasal obstruction, forehead pain, hypomnesis, thin and wiry pulse diagnosis, purple and fat tongue with tooth marks and yellow and greasy coating. Western diagnosis: chronic gastritis. The pulse syndrome is combined with the parameters, and the syndrome differentiation of the traditional Chinese medicine is epigastric pain, and belongs to the syndrome of liver qi invading the stomach. The treatment method comprises the following steps: liver soothing, qi regulating and pain relieving. Fang Yongjie modified Lianchashao Jiwei Zhitong Tang (decoction of Chaihua of the invention for regulating stomach and relieving pain): 15g of bupleurum, 10g of white peony root, 10g of immature bitter orange, 10g of honey-fried licorice root, 10g of nutgrass galingale rhizome, 12g of rhizoma corydalis, 15g of costustoot, 30g of fructus amomi, 15g of poria cocos, 12g of dried orange peel, 10g of medicated leaven, 10g of fennel, wu Zhu g of root of three-nerved spicebush, 10g of fingered citron, 15g of galangal, 10g of bamboo shavings, 10g of Chinese yam, 6g of szechuan lovage rhizome and 15g of dandelion, 40g of fried two buds each, and 5 ginger slices are added as guiding drugs. 5 doses. The nasal obstruction of the patient does not smell odor, yellow and thick nasal discharge, forehead pain and hypomnesis for 1 year, which belongs to the nasosinusitis, treats the disease as aromatic resuscitation, and uses the university of medical staff Wang Jingan to treat the disease from the pseudoprescription: 15g of schizonepeta flower, 15g of mint leaf, 10g of asarum, 15g of radix angelicae, and the patient is instructed to make the four medicines into powder, and the powder is divided into two parts to be wrapped by gauze, and one part is wrapped on the body to be smelled at any time, and the other part is wrapped under the pillow. After taking the medicine for 4 doses, the pain in the gastric cavity is obviously relieved, the vexation and irritability and the somnolence and anorexia are eliminated, but still the acid water is still vomit. 20g of calcined concha arcae and 5 doses of calcined concha arcae are added to the original prescription. In addition, 60g of cuttlefish bone, 60g of rhizoma corydalis, 30g of aspongopus, 20g of cardamom and 30g of radix bupleuri are ground into fine powder, 15g each time, 3 times a day, and the mixture is taken with boiled water and honey, and the nose-smoothing powder is used for a long time. Three diagnoses after taking 5 doses, the pain of the gastric cavity disappears, no abnormality is seen in gastroscopy, the sleep and the food are good, the spirit is transformed into a high state, and the nasosinusitis is cured. To consolidate the curative effect, 4 doses of self-made spleen-strengthening and stomach-harmonizing soup are taken instead: 15g of codonopsis pilosula, 9g of bighead atractylodes rhizome, 12g of cardamom (smashed later), 10g of dried orange peel, 10g of immature bitter orange, 30g of hawthorn, 30g of roasted malt and 10g of honey. The following symptoms heal.
2.2 Liu Mou, man, 48 years old, worker. For more than 5 years, the patients often suffer from gastric fullness, distension and discomfort, severe stomach pain, severe fasting, slow appetite, hunger, lassitude and debilitation, and digestion in the day. Frequent treatment by multi-part Chinese and Western medicine diagnosis (detailed diagnosis) but poor curative effect, light and heavy illness state, obvious aggravation of pain in the gastric cavity after about 10 days of intense anger and qi due to work, gastroscopy in a certain hospital and diagnosis of chronic superficial gastritis. The students introduce the diagnosis and treatment of the person who finds his pen. Symptoms are epigastric severe pain, belch, noisy, vexation, dry and bitter taste, nausea, wiry and rapid pulse diagnosis, bao Huangyou stasis spots on tongue coating and pale purple and thick and long sublingual venation. Western diagnosis: chronic gastritis. The pulse syndrome is combined with the parameters, and the syndrome differentiation of the traditional Chinese medicine is epigastric pain, and belongs to the type of liver depression and qi stagnation, blood stasis and stomach collaterals. The treatment method comprises the following steps: liver soothing, qi stagnation relieving, qi and blood circulation promoting, stomach harmonizing and pain relieving. Fang Yongjie modified Lianchashao Jiwei Zhitong Tang (decoction of Chaihua of the invention for regulating stomach and relieving pain): 15g of vinegar radix bupleuri, 9g of white peony root, 10g of vinegar nutgrass galingale rhizome, 12g of corydalis tuber, 12g of turmeric root-tuber, 10g of golden bell charcoal, 6g of szechuan lovage rhizome, 10g of frankincense, 10g of myrrh, 15g of dandelion, 10g of red sage root, 15g of dandelion, 3g of coptis root, wu g of stir-fried largehead atractylodes rhizome, 12g of cardamom (smashed, later ground), 40g of stir-fried two buds, 10g of honey-fried liquorice and 5 doses. After two weeks of administration, the symptoms were greatly reduced. Modified recipe (A) for treating more than two months, the pain of gastric cavity is eliminated, appetite is recovered, weight is increased, and spirit is improved. To consolidate the curative effect, 3 doses of self-made spleen-strengthening and stomach-harmonizing soup are ordered to be taken: 15g of codonopsis pilosula, 10g of bighead atractylodes rhizome, 12g of cardamom (smashed later), 5g of dried orange peel, 5g of immature bitter orange, 30g of hawthorn, 30g of roasted malt and 10g of honey. Diet nursing is prescribed, and the patients with the following symptoms are cured.
It will be apparent to those skilled in the art that various modifications and variations can be made to the present invention without departing from the spirit or scope of the invention. Thus, it is intended that such modifications and variations be included herein within the scope of the appended claims and their equivalents.

Claims (7)

1. The traditional Chinese medicine composition for treating epigastric pain is characterized by comprising the following raw materials in parts by weight: 14-16 parts of bupleurum, 9-11 parts of white peony root, 9-11 parts of immature bitter orange, 9-11 parts of honey-fried licorice root, 9-11 parts of nutgrass galingale rhizome, 11-13 parts of rhizoma corydalis, 14-16 parts of costustoot, 29-31 parts of fructus amomi, 14-16 parts of poria cocos, 11-13 parts of dried orange peel, 9-11 parts of medicated leaven, 9-11 parts of fennel, wu Zhu-4 parts of root of three-nerved spicebush, 11-13 parts of fingered citron, 14-16 parts of galangal, 9-11 parts of bamboo shavings, 9-11 parts of Chinese yam, 39-41 parts of fried malt, 39-41 parts of fried rice sprout and 14-16 parts of dandelion.
2. The traditional Chinese medicine composition for treating epigastric pain according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 15 parts of radix bupleuri, 10 parts of white peony root, 10 parts of immature bitter orange, 10 parts of honey-fried licorice root, 10 parts of nutgrass galingale rhizome, 12 parts of rhizoma corydalis, 15 parts of costustoot, 30 parts of fructus amomi, 15 parts of poria cocos, 12 parts of dried orange peel, 10 parts of medicated leaven, 10 parts of fennel, parts of evodia rutaecarpa, 12 parts of lindera root, 10 parts of fingered citron, 15 parts of galangal, 10 parts of bamboo shavings, 10 parts of Chinese yam, 40 parts of roasted malt, 40 parts of roasted rice sprout and 15 parts of dandelion.
3. The method for preparing the traditional Chinese medicine composition for treating epigastric pain according to claim 1 or 2, wherein the dosage form prepared from the traditional Chinese medicine composition comprises decoction, powder, medicinal granules, oral liquid or tablets.
4. The preparation method of claim 3, wherein the dosage form of the traditional Chinese medicine composition is decoction, and the preparation method comprises the following steps:
the following raw materials in parts by weight are respectively weighed: 14-16 parts of bupleurum, 9-11 parts of white peony root, 9-11 parts of immature bitter orange, 9-11 parts of honey-fried licorice root, 9-11 parts of nutgrass galingale rhizome, 11-13 parts of rhizoma corydalis, 14-16 parts of costustoot, 29-31 parts of fructus amomi, 14-16 parts of poria cocos, 11-13 parts of dried orange peel, 9-11 parts of medicated leaven, 9-11 parts of fennel, wu Zhu-4 parts of radix linderae, 11-13 parts of lindera root, 9-11 parts of fingered citron, 14-16 parts of galangal, 9-11 parts of bamboo shavings, 9-11 parts of Chinese yam, 39-41 parts of fried malt, 39-41 parts of fried rice sprout and 14-16 parts of dandelion;
soaking the above materials in water, decocting, boiling with strong fire, decocting with slow fire, and filtering.
5. The method according to claim 4, wherein the soaking time is 25-35min.
6. The method according to claim 4, wherein the mixture is boiled with strong fire for 9-11min and then decocted with slow fire for 4-6 min.
7. The use of the traditional Chinese medicine composition according to claim 1 in preparing a medicament for treating epigastric pain.
CN202310249558.2A 2023-03-15 2023-03-15 Traditional Chinese medicine composition for treating epigastric pain and preparation method and application thereof Withdrawn CN116350729A (en)

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