CN108310302B - Pharmaceutical composition for treating chronic gastritis - Google Patents
Pharmaceutical composition for treating chronic gastritis Download PDFInfo
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Abstract
The invention belongs to the technical field of traditional Chinese medicines, and relates to a pharmaceutical composition for treating chronic gastritis, which comprises the following traditional Chinese medicine raw materials in parts by weight: 3-10 parts of costustoot, 3-6 parts of fructus amomi, 10-30 parts of radix pseudostellariae, 5-15 parts of fried bighead atractylodes rhizome, 10-20 parts of poria cocos, 2-5 parts of liquorice, 5-15 parts of ginger processed pinellia tuber, 4-8 parts of fried dried orange peel, 5-15 parts of fried fructus aurantii, 5-10 parts of ginger processed bamboo shavings, 15-30 parts of concha arcae, 5-15 parts of moutan bark, 15-30 parts of fried rice sprout and 15-30 parts of fried malt or the components are subjected to addition and subtraction of medicines, and the pharmaceutical composition has obvious curative effect, quick taking effect, difficult recurrence and no toxic or side effect, and has wide clinical application prospect.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and relates to a pharmaceutical composition for treating chronic gastritis.
Background
Chronic gastritis refers to various chronic gastric mucositis lesions caused by different causes, and is one of common diseases of the digestive system. The traditional Chinese medicine considers that the chronic gastritis is related to various factors such as weakness of spleen and stomach, emotional disorder, improper diet, medicines, exogenous evil (helicobacter pylori infection) and the like, the disease is in the stomach and is closely related to liver and spleen, and the traditional Chinese medicine differentiation divides the chronic gastritis into liver-stomach disharmony type (comprising liver-stomach qi stagnation and liver-stomach stagnation heat), spleen-stomach damp-heat type, spleen-stomach weakness type (comprising spleen-stomach qi deficiency and spleen-stomach deficiency cold type), stomach-yin deficiency type and stomach-collateral stasis type.
At present, western medicines mainly adopt methods of inhibiting acid, repairing gastric mucosa, regulating gastrointestinal motility, killing helicobacter pylori and the like to prevent and treat chronic gastritis, on one hand, the treatment effect is unsatisfactory, and the symptoms are repeated; on the other hand, the potential drug resistance problem also greatly limits the using effect of western medicines. The traditional Chinese medicine is used for determining the specific symptom type of the stomach illness according to the spirit of the prescription, and the corresponding prescription is given, so that the medicine starts from improving the stomach and intestine pathological condition of a patient and recovering the stomach and intestine function, and has obvious effect, therefore, the traditional Chinese medicine is used for treating the chronic gastritis, has the advantages of simultaneous functions of symptoms and root causes, is safe and effective, is not easy to repeat, and has great market prospect.
However, for patients with spleen and stomach damp-heat type chronic gastritis, the internal damp-heat accumulation, heat clearing, dampness removing, and heat generating are difficult to treat, and the traditional Chinese medicine treatment is slow in taking effect, so that higher treatment requirements are provided for spleen and stomach damp-heat type chronic gastritis.
Disclosure of Invention
The invention aims to provide a pharmaceutical composition for treating chronic gastritis, in particular to a pharmaceutical composition for treating spleen and stomach damp-heat type chronic gastritis, which has the advantages of obvious curative effect, quick response, difficult recurrence, no toxic or side effect and wide clinical application prospect.
The invention provides a pharmaceutical composition for treating chronic gastritis, which comprises the following traditional Chinese medicine raw materials in parts by weight: 3-10 parts of costustoot, 3-6 parts of fructus amomi, 10-30 parts of radix pseudostellariae, 5-15 parts of fried bighead atractylodes rhizome, 10-20 parts of poria cocos, 2-5 parts of liquorice, 5-15 parts of ginger processed pinellia tuber, 4-8 parts of fried dried orange peel, 5-15 parts of fried fructus aurantii, 5-10 parts of ginger processed bamboo shavings, 15-30 parts of concha arcae, 5-15 parts of tree peony bark, 15-30 parts of fried rice sprout and 15-30 parts of fried malt.
In some preferred embodiments, the pharmaceutical composition for treating chronic gastritis provided by the invention comprises the following traditional Chinese medicine raw materials in parts by weight: 5-10 parts of costustoot, 4-5 parts of fructus amomi, 10-20 parts of radix pseudostellariae, 10-15 parts of fried bighead atractylodes rhizome, 15-20 parts of poria cocos, 2-5 parts of liquorice, 5-10 parts of ginger processed pinellia, 5-6 parts of fried dried orange peel, 5-10 parts of fried fructus aurantii, 5-8 parts of ginger bamboo shavings, 15-20 parts of concha arcae, 5-10 parts of tree peony bark, 15-30 parts of fried rice sprout and 15-30 parts of fried malt.
In some preferred embodiments, the pharmaceutical composition for treating chronic gastritis provided by the invention comprises the following traditional Chinese medicine raw materials in parts by weight: 6 parts of costustoot, 5 parts of fructus amomi, 15 parts of radix pseudostellariae, 10 parts of fried bighead atractylodes rhizome, 15 parts of poria cocos, 3 parts of liquorice, 10 parts of ginger processed pinellia, 6 parts of fried dried orange peel, 10 parts of fried bitter orange, 6 parts of ginger processed bamboo shavings, 20 parts of concha arcae, 10 parts of tree peony bark, 20 parts of fried rice sprout and 20 parts of fried malt.
The present inventors consider that, from the dialectical aspect of the traditional Chinese medicine, the root cause of chronic gastritis due to damp-heat in spleen and stomach is the accumulation of damp-heat, spleen deficiency and qi stagnation, so the recipe takes costustoot, fructus amomi and radix pseudostellariae as the monarch, and has the effects of clearing damp, stimulating appetite, warming spleen, tonifying qi and tonifying blood. Radix aucklandiae, pungent and bitter in taste, warm in nature, promoting qi circulation, relieving pain, invigorating spleen, promoting digestion, promoting qi circulation, relieving pain, regulating middle warmer and removing stagnation; fructus Amomi, pungent in flavor, warm in nature, and has the effects of invigorating spleen, stomach and kidney meridian, promoting qi circulation, regulating middle warmer, eliminating dampness, stimulating appetite and warming spleen; radix pseudostellariae is sweet in taste, slightly bitter, flat in nature, and has the effects of invigorating spleen and lung channel, replenishing qi to invigorate spleen, promoting fluid production and moistening lung, tonifying qi and blood, promoting fluid production and tonifying spleen and stomach. Radix aucklandiae is used for qi consumption, guiding the medicines, and radix Pseudostellariae is used for tonifying qi but not lifting, promoting fluid production but not promoting dampness, strengthening body resistance but not loving evil, tonifying deficiency and not strong, warming and strengthening body resistance, and tonifying qi and spleen. The method takes the stir-fried bighead atractylodes rhizome and poria cocos as ministerial drugs, and has the effects of promoting the circulation of the dampness, strengthening the spleen and tonifying qi. Roasted white atractylodes rhizome, rhizoma Atractylodis Macrocephalae, bitter in taste, warm in nature, and capable of invigorating spleen meridian, strengthening spleen and replenishing qi, and drying dampness and promoting diuresis; poria cocos is sweet and light in taste, flat in nature, and capable of inducing heart, lung, spleen and kidney meridians, excreting dampness and promoting diuresis, strengthening spleen and stomach, calming heart and tranquilizing mind, and the fried bighead atractylodes rhizome is capable of strengthening spleen and not drying, and the drying power is increased, and the fried bighead atractylodes rhizome and the poria cocos are matched as ministerial drugs for dispelling dampness, warming spleen and tonifying qi. The method takes liquorice, ginger processed pinellia, fried dried orange peel, concha arcae, moutan bark, fried rice sprout and fried malt as adjuvants, and the liquorice has sweet taste, flat nature, returns to heart, lung, spleen and stomach channels, has the effects of clearing heat and detoxicating, relieving cough and eliminating phlegm, tonifying spleen and harmonizing stomach and harmonizing various medicines; ginger processed pinellia tuber, rhizoma Pinelliae, pungent in flavor, warm in nature, enter spleen, stomach and lung meridians, warm middle energizer and dry dampness, and descend adverse qi to arrest vomiting; stir-baked dried orange peel, pungent and bitter, warm nature, return to the tablet, regulate the lung channel, regulate qi, invigorate the spleen, dry dampness and resolve phlegm; fried fructus aurantii, bitter, pungent and sour in taste, warm in nature, and capable of invigorating spleen and stomach channels, regulating qi-flowing, relieving chest stuffiness, promoting digestion, promoting appetite, regulating five viscera, descending qi, relieving vomiting and adverse flow of qi, and eliminating phlegm; ginger and bamboo shavings are sweet in taste and slightly cold in nature, enter lung, stomach, heart and gallbladder meridians, clear heat, cool blood, resolve phlegm, relieve restlessness and arrest vomiting; corrugated seeds, salty in taste, flat in nature, and capable of invigorating lung, stomach and liver meridians, resolving phlegm and removing blood stasis, softening hardness and resolving hard mass, and relieving hyperacidity and pain; cortex moutan, bitter and pungent in flavor, slightly cold in nature, enters heart, liver and kidney meridians, and has the effects of clearing heat and cooling blood, and activating blood circulation to dissipate blood stasis; stir-baked rice sprout, sweet in taste, warm in nature, entering spleen and stomach meridians, strengthening spleen and stimulating appetite, and regulating stomach and promoting digestion; the fried malt has sweet taste and flat nature, and can enter spleen and stomach channels, sooth liver and relieve depression, promote qi circulation and promote digestion, harmonize middle energizer and lower energizer, remove dampness and heat by removing dampness and dampness by adopting the following components of the concha arcae to relieve hyperacidity and pain, stir-fried rice sprout and stir-fried malt to invigorate spleen and promote appetite, and meanwhile, the liquorice is used for harmonizing various medicines, the liquorice, ginger processed pinellia, stir-fried dried orange peel, concha arcae, tree peony bark, stir-fried rice sprout and stir-fried malt are matched to serve as auxiliary medicines, and are mutually required with monarch medicines and ministerial medicines, the monarch medicines and ministerial medicines are used for removing dampness and strengthening spleen and promoting appetite, and the adjuvant medicines and the drug-protecting prescription are not warm and cool and tend to be flat, so that the effect of removing dampness and clearing heat is unique.
The traditional Chinese medicine formula provided by the invention has the effects of clearing damp and heat, harmonizing stomach and inhibiting acid, invigorating stomach and promoting digestion, and has the advantages of definite curative effect, quick response, high cure rate, no toxic or side effect and the like on spleen and stomach damp-heat type chronic gastritis. For patients with spleen and stomach damp-heat type chronic gastritis with different symptoms, the medicine is modified based on the recipe, for example, 20 parts by weight of coptis chinensis, evodia rutaecarpa, fritillary bulb and cuttlefish bone or the combination of the above medicines are decocted in the liver for treating the patients with obvious acid regurgitation; for patients with dysphoria and liver fire, 15 parts of selfheal, 10 parts of tribulus terrestris and 15 parts of white paeony root are added; for those with severe epigastric pain, 10 parts by weight of rhizoma corydalis and 20 parts by weight of stir-fried white peony root are added; for people with severe cold, 5 parts by weight of dried ginger, 6 parts by weight of cinnamon or 3 parts by weight of agilawood is added; rhizoma Cyperi, radix Curcumae, flos Albiziae or combined Sili powder for treating depression; 10 parts of mangnolia officinalis, 10 parts of paniculate swallowwort root and 10 parts of betel nut, wherein the fullness in the stomach obviously belongs to damp obstruction; for patients with thick and greasy tongue coating, 10 parts of herba Agastaches herba Eupatorii, 30 parts of Coicis semen, 30 parts of semen Benincasae, 5 parts of fructus Amomi rotundus, and 20 parts of rhizoma Smilacis Glabrae are added; 6 parts of semen katsumadai for cold-dampness patients and 6 parts of fructus tsaoko for cold-dampness patients; for damp-heat patients, 5 weight parts of coptis chinensis and 1 weight part of baikal skullcap root are added, which are all within the scope of the invention.
Detailed Description
The traditional Chinese medicine raw materials used in the invention can be obtained commercially. The following examples illustrate the invention but are not limited thereto.
Example 1
A pharmaceutical composition for treating spleen and stomach damp-heat type chronic gastritis is prepared from the following traditional Chinese medicine raw materials of 3g of costustoot, 5g of fructus amomi, 30g of radix pseudostellariae, 5g of fried bighead atractylodes rhizome, 15g of poria cocos, 5g of liquorice, 5g of ginger processed pinellia, 6g of fried dried orange peel, 5g of fried fructus aurantii, 5g of ginger processed bamboo shavings, 15g of concha arcae, 15g of tree peony bark, 30g of fried rice sprout and 30g of fried malt.
Example 2
A pharmaceutical composition for treating spleen and stomach damp-heat type chronic gastritis is prepared from the following traditional Chinese medicine raw materials of 10g of costustoot, 6g of fructus amomi, 20g of radix pseudostellariae, 10g of fried bighead atractylodes rhizome, 20g of poria cocos, 3g of liquorice, 15g of ginger processed pinellia, 8g of fried dried orange peel, 15g of fried fructus aurantii, 10g of ginger processed bamboo shavings, 30g of concha arcae, 10g of tree peony bark, 20g of fried rice sprout and 20g of fried malt.
Example 3
A pharmaceutical composition for treating spleen and stomach damp-heat type chronic gastritis is prepared from the following traditional Chinese medicine raw materials of 5g of costustoot, 4g of fructus amomi, 15g of radix pseudostellariae, 15g of fried bighead atractylodes rhizome, 15g of poria cocos, 2g of liquorice, 10g of ginger processed pinellia, 6g of fried dried orange peel, 10g of fried fructus aurantii, 8g of ginger processed bamboo shavings, 15g of concha arcae, 5g of tree peony bark, 15g of fried rice sprout and 15g of fried malt.
Example 4
A pharmaceutical composition for treating spleen and stomach damp-heat type chronic gastritis is prepared from the following traditional Chinese medicine raw materials of 10g of costustoot, 5g of fructus amomi, 20g of radix pseudostellariae, 10g of fried bighead atractylodes rhizome, 20g of poria cocos, 5g of liquorice, 10g of ginger processed pinellia, 5g of fried dried orange peel, 5g of fried fructus aurantii, 5g of ginger processed bamboo shavings, 20g of concha arcae, 10g of tree peony bark, 20g of fried rice sprout and 20g of fried malt.
Example 5
A pharmaceutical composition for treating spleen and stomach damp-heat type chronic gastritis is prepared from the following traditional Chinese medicine raw materials of 6g of costustoot, 5g of fructus amomi, 15g of radix pseudostellariae, 10g of fried bighead atractylodes rhizome, 15g of poria cocos, 3g of liquorice, 10g of ginger processed pinellia, 6g of fried dried orange peel, 10g of fried fructus aurantii, 6g of ginger processed bamboo shavings, 20g of concha arcae, 10g of tree peony bark, 20g of fried rice sprout and 20g of fried malt.
Example 6
A pharmaceutical composition for treating spleen and stomach damp-heat type chronic gastritis is prepared from the following traditional Chinese medicine raw materials of 6g of costustoot, 5g of fructus amomi, 15g of radix pseudostellariae, 10g of fried bighead atractylodes rhizome, 15g of poria cocos, 3g of liquorice, 10g of ginger processed pinellia, 6g of fried dried orange peel, 10g of fried fructus aurantii, 6g of ginger processed bamboo shavings, 20g of concha arcae, 10g of tree peony bark, 20g of fried rice sprout, 20g of fried malt, 15g of selfheal, 10g of tribulus terrestris and 15g of white paeony root.
Example 7
A pharmaceutical composition for treating spleen and stomach damp-heat type chronic gastritis is prepared from the following traditional Chinese medicine raw materials of 6g of costustoot, 5g of fructus amomi, 15g of radix pseudostellariae, 10g of fried bighead atractylodes rhizome, 15g of poria cocos, 3g of liquorice, 10g of ginger processed pinellia, 6g of fried dried orange peel, 10g of fried fructus aurantii, 6g of ginger processed bamboo shavings, 20g of concha arcae, 10g of tree peony bark, 20g of fried rice sprout, 20g of fried malt, 20g of coptis chinensis, 20g of fructus evodiae, 20g of fritillaria thunbergii and 20g of cuttlefish bone.
Example 8
A pharmaceutical composition for treating spleen and stomach damp-heat type chronic gastritis is prepared from the following traditional Chinese medicine raw materials of 6g of costustoot, 5g of fructus amomi, 15g of radix pseudostellariae, 10g of fried bighead atractylodes rhizome, 15g of poria cocos, 3g of liquorice, 10g of ginger processed pinellia, 6g of fried dried orange peel, 10g of fried fructus aurantii, 6g of ginger processed bamboo shavings, 20g of concha arcae, 10g of tree peony bark, 20g of fried rice sprout, 20g of fried malt, 10g of rhizoma corydalis and 20g of fried white peony root.
Example 9
A pharmaceutical composition for treating spleen and stomach damp-heat type chronic gastritis is prepared from the following traditional Chinese medicine raw materials of 6g of costustoot, 5g of fructus amomi, 15g of radix pseudostellariae, 10g of fried bighead atractylodes rhizome, 15g of poria cocos, 3g of liquorice, 10g of ginger processed pinellia, 6g of fried dried orange peel, 10g of fried fructus aurantii, 6g of ginger processed bamboo shavings, 20g of concha arcae, 10g of tree peony bark, 20g of fried rice sprout, 20g of fried malt, 5g of dried ginger and 6g of cinnamon.
Example 10
A pharmaceutical composition for treating spleen and stomach damp-heat type chronic gastritis is prepared from the following traditional Chinese medicine raw materials of 6g of costustoot, 5g of fructus amomi, 15g of radix pseudostellariae, 10g of fried bighead atractylodes rhizome, 15g of poria cocos, 3g of liquorice, 10g of ginger processed pinellia, 6g of fried dried orange peel, 10g of fried fructus aurantii, 6g of ginger processed bamboo shavings, 20g of concha arcae, 10g of tree peony bark, 20g of fried rice sprout, 20g of fried malt, 5g of dried ginger and 3g of agilawood.
Example 11
A pharmaceutical composition for treating spleen and stomach damp-heat type chronic gastritis is prepared from the following traditional Chinese medicine raw materials of 6g of costustoot, 5g of fructus amomi, 15g of radix pseudostellariae, 10g of fried bighead atractylodes rhizome, 15g of poria cocos, 3g of liquorice, 10g of ginger processed pinellia, 6g of fried dried orange peel, 10g of fried fructus aurantii, 6g of ginger processed bamboo shavings, 20g of concha arcae, 10g of tree peony bark, 20g of fried rice sprout, 20g of fried malt, 10g of wrinkled gianthyssop herb, 10g of eupatorium, 30g of coix seed, 30g of white gourd seed, 5g of cardamom and 20g of glabrous greenbrier rhizome.
Example 12
A pharmaceutical composition for treating spleen and stomach damp-heat type chronic gastritis is prepared from the following traditional Chinese medicine raw materials of 6g of costustoot, 5g of fructus amomi, 15g of radix pseudostellariae, 10g of fried bighead atractylodes rhizome, 15g of poria cocos, 3g of liquorice, 10g of ginger processed pinellia, 6g of fried dried orange peel, 10g of fried fructus aurantii, 6g of ginger processed bamboo shavings, 20g of concha arcae, 10g of tree peony bark, 20g of fried rice sprout, 20g of fried malt, 10g of mangnolia officinalis, 10g of paniculate swallowwort root and 10g of betel nut.
Example 13
A pharmaceutical composition for treating spleen and stomach damp-heat type chronic gastritis is prepared from the following traditional Chinese medicine raw materials of 6g of costustoot, 5g of fructus amomi, 15g of radix pseudostellariae, 10g of fried bighead atractylodes rhizome, 15g of poria cocos, 3g of liquorice, 10g of ginger processed pinellia, 6g of fried dried orange peel, 10g of fried fructus aurantii, 6g of ginger processed bamboo shavings, 20g of concha arcae, 10g of tree peony bark, 20g of fried rice sprout, 20g of fried malt and 6g of semen katsumadai.
Example 14
A pharmaceutical composition for treating spleen and stomach damp-heat type chronic gastritis is prepared from the following traditional Chinese medicine raw materials of 6g of costustoot, 5g of fructus amomi, 15g of radix pseudostellariae, 10g of fried bighead atractylodes rhizome, 15g of poria cocos, 3g of liquorice, 10g of ginger processed pinellia, 6g of fried dried orange peel, 10g of fried fructus aurantii, 6g of ginger processed bamboo shavings, 20g of concha arcae, 10g of tree peony bark, 20g of fried rice sprout, 20g of fried malt and 6g of tsaoko cardamon.
Example 15
A pharmaceutical composition for treating spleen and stomach damp-heat type chronic gastritis is prepared from the following traditional Chinese medicine raw materials of 6g of costustoot, 5g of fructus amomi, 15g of radix pseudostellariae, 10g of fried bighead atractylodes rhizome, 15g of poria cocos, 3g of liquorice, 10g of ginger processed pinellia, 6g of fried dried orange peel, 10g of fried fructus aurantii, 6g of ginger processed bamboo shavings, 20g of concha arcae, 10g of tree peony bark, 20g of fried rice sprout, 20g of fried malt, 5g of coptis and 1g of radix scutellariae.
The formulations of examples 1-15 were decocted according to the following procedure: weighing the traditional Chinese medicine raw materials according to the formula, putting the traditional Chinese medicine raw materials into a container, adding water, soaking the traditional Chinese medicine raw materials for 20-30 minutes after soaking the traditional Chinese medicine raw materials in the medicine powder, decocting the traditional Chinese medicine raw materials with strong fire until the traditional Chinese medicine raw materials are boiled, decocting the traditional Chinese medicine raw materials with slow fire for 20 minutes, and taking filtrate; adding water, decocting with strong fire to boil, decocting with slow fire for 15 min, collecting filtrate, and mixing the filtrates.
The pharmaceutical composition of the embodiment 5 of the invention is decocted for treating more than 100 cases of patients with spleen and stomach damp-heat type chronic gastritis, wherein 79 cases of men and 21 cases of women have average ages of 50 years, the course of the disease is 1-3 years, 250-300ml each time, and the patients are cured twice a day, and the clinical cure is achieved by referring to 'the combination diagnosis, differentiation and curative effect standard of traditional Chinese and western medicine for chronic gastritis': the clinical main symptoms disappear, the active inflammation disappears in gastroscopy, and the chronic inflammation is improved to be mild; the effect is shown: the main symptoms are obviously reduced, the range of the mucosa lesion is reduced by more than half by gastroscopy, and the inflammation is reduced to some extent; invalidation: symptoms are unchanged, gastroscopy does not reach the effective standard, and the patients are not worsened. The results show that: the treatment course is 3-6 months, 9 cases are clinically cured, 68 cases are effectively treated, 18 cases are effectively treated, 5 cases are not effectively treated, and the total effective rate is 95%.
Typical clinical cases
Case 1
The patient, who is a certain man, is 45 years old, has a hidden pain in the stomach, has a diet of nearly no thinking, has red tongue, has tooth marks on the fat side of the tongue, has yellow fur, has deep and slippery pulse, and is not cured by intermittent consultation at the clinic in the hospital, and the medicine composition of the embodiment 5 of the invention is administered for 3 days to relieve symptoms, and the main symptoms are obviously relieved after the medicine composition is continuously taken for 1 month, and no recurrence is seen for 1 year in follow-up.
Case 2
The patient Li Mou, female, 39 years old, gastric cavity burning, distending pain and pain for more than 1 month, bitter taste and halitosis, yellow urine, red tongue, deep red edge tip, yellow thick or greasy coating, and wiry or slippery pulse, and the medicine composition of the invention in example 5 is administered for 5 days to relieve symptoms, and is cured after being continuously taken for 2 months, and no recurrence is seen in 1 year of follow-up.
Case 3
The medicine composition of the invention of the example 7 is applied to patients Dai Mou, men, 31 years old, gastric cavity burning, distending pain and pain for more than 1 month, acid regurgitation, bitter taste and halitosis, deep red tongue edge tip, yellow thick or greasy tongue coating, and wiry or slippery pulse, and the symptoms are obviously relieved after treatment for 11 days, and the patients are cured after continuing to take for 1 month, and relapse is not seen in half a follow-up visit.
Case 4
The patient, somebody in clock, 49 years old, gastric cavity burning, distending pain and pain for more than 1 month, acid regurgitation, liver fire heavy, spleen qi dryness, bitter taste in mouth and halitosis, yellow tongue coating and deep and slippery pulse are given the pharmaceutical composition of the invention example 6, the symptoms are obviously relieved after treatment for 7 days, the patient is basically healed after continuing to take for 2 months, and no relapse is seen in half a year of follow-up.
Case 5
The medicine composition of the invention of the example 8 is administered for 5 days to relieve symptoms, and the symptoms are obviously relieved when continuously taken for half a month, and no recurrence is seen in half a year after follow-up.
Case 6
The patient Xue Mou, male, 47 years old, gastric cavity burning, distending pain for 7 days, near missing diet, red tongue, yellow, thick or greasy coating and deep and slippery pulse, and the medicine composition of the invention of example 11 is applied for treating 3 days of symptom relief, and the symptom is obviously relieved after the medicine composition is continuously taken for 7 months, and no recurrence is seen in the follow-up half a year.
Case 7
The patients, tang somewhere, men, 41 years old, and gastric cavity burning, distending pain and pain for half a year, the western medicine outpatient service is treated for 5 times of repeated recrudescence, the tongue is red, the coating is yellow and thick or greasy, the pulse is deep and slippery, and the body is cold and wet, and the symptoms are relieved after the medicine composition of the embodiment 14 is applied for 7 days, the symptoms are obviously relieved after the medicine composition is continuously taken for 2 months, and no recrudescence is seen in one year of follow-up.
The invention is not limited to the above, but any person skilled in the art may make modifications or alterations to the disclosed technical content to equivalent embodiments, which still fall within the scope of the technical solution of the present invention.
Claims (3)
1. The medicine composition for treating the chronic gastritis is characterized by being prepared from the following traditional Chinese medicine raw materials in parts by weight: 3-10 parts of costustoot, 3-6 parts of fructus amomi, 10-30 parts of radix pseudostellariae, 5-15 parts of fried bighead atractylodes rhizome, 10-20 parts of poria cocos, 2-5 parts of liquorice, 5-15 parts of ginger processed pinellia, 4-8 parts of fried dried orange peel, 5-15 parts of fried fructus aurantii, 5-10 parts of ginger processed bamboo shavings, 15-30 parts of concha arcae, 5-15 parts of tree peony bark, 15-30 parts of fried rice sprout, 15-30 parts of fried malt, 10 parts of wrinkled gianthyssop, 10 parts of eupatorium, 30 parts of coix seed, 30 parts of semen benincasae, 5 parts of cardamom and 20 parts of rhizoma smilacis glabrae.
2. The pharmaceutical composition for treating chronic gastritis according to claim 1, which is characterized by being prepared from the following traditional Chinese medicine raw materials in parts by weight: 6 parts of costustoot, 5 parts of fructus amomi, 15 parts of radix pseudostellariae, 10 parts of fried bighead atractylodes rhizome, 15 parts of poria cocos, 3 parts of liquorice, 10 parts of ginger processed pinellia, 6 parts of fried dried orange peel, 10 parts of fried bitter orange, 6 parts of ginger processed bamboo shavings, 20 parts of concha arcae, 10 parts of tree peony bark, 20 parts of fried rice sprout, 20 parts of fried malt, 10 parts of wrinkled gianthyssop herb, 10 parts of eupatorium, 30 parts of coix seed, 30 parts of semen benincasae, 5 parts of cardamom and 20 parts of rhizoma smilacis glabrae.
3. The pharmaceutical composition for treating chronic gastritis according to claim 1 or 2, wherein the chronic gastritis is spleen and stomach damp-heat type chronic gastritis.
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20020006062A (en) * | 2000-07-11 | 2002-01-19 | 김철희 | Powdered composition of health food having an effect against a stomach disorder |
| CN103751739A (en) * | 2013-12-30 | 2014-04-30 | 南京海思创新生物科技有限公司 | Traditional Chinese medicine composition for treating chronic gastritis, application of composition in preparation of medicine for treating chronic gastritis, and preparation method of composition |
| CN104547683A (en) * | 2014-12-26 | 2015-04-29 | 江苏苏南药业实业有限公司 | Traditional Chinese medicine composition for treating chronic gastritis and preparation method of traditional Chinese medicine composition |
| CN104922546A (en) * | 2015-06-12 | 2015-09-23 | 广西大学 | Traditional Chinese medicine composition curing chronic gastritis and preparation method thereof |
| WO2017101155A1 (en) * | 2015-12-14 | 2017-06-22 | 华坚 | Gardenia herbal tea for clearing heat and expelling dampness and preparation method therefor |
-
2018
- 2018-03-27 CN CN201810255980.8A patent/CN108310302B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20020006062A (en) * | 2000-07-11 | 2002-01-19 | 김철희 | Powdered composition of health food having an effect against a stomach disorder |
| CN103751739A (en) * | 2013-12-30 | 2014-04-30 | 南京海思创新生物科技有限公司 | Traditional Chinese medicine composition for treating chronic gastritis, application of composition in preparation of medicine for treating chronic gastritis, and preparation method of composition |
| CN104547683A (en) * | 2014-12-26 | 2015-04-29 | 江苏苏南药业实业有限公司 | Traditional Chinese medicine composition for treating chronic gastritis and preparation method of traditional Chinese medicine composition |
| CN104922546A (en) * | 2015-06-12 | 2015-09-23 | 广西大学 | Traditional Chinese medicine composition curing chronic gastritis and preparation method thereof |
| WO2017101155A1 (en) * | 2015-12-14 | 2017-06-22 | 华坚 | Gardenia herbal tea for clearing heat and expelling dampness and preparation method therefor |
Non-Patent Citations (2)
| Title |
|---|
| 袁保等.《长春中医药大学学报》.2017,第62页左栏第1-3段. * |
| 黄培容等.《胃肠病》.第147页. * |
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