CN103007170B

CN103007170B - Chinese medicinal composition for treating recurrent oral ulcer

Info

Publication number: CN103007170B
Application number: CN201210482091.8A
Authority: CN
Inventors: 李静; 郭磊; 柳晖
Original assignee: Individual
Current assignee: Li jing
Priority date: 2012-11-25
Filing date: 2012-11-25
Publication date: 2014-08-20
Anticipated expiration: 2032-11-25
Also published as: CN103007170A

Abstract

The invention relates to a Chinese medicinal composition for treating recurrent oral ulcer, which consists of the following Chinese medicinal raw materials in parts by weight: 10 to 30 parts of rhizoma picrorhizae, 5 to 20 parts of golden cypress, 5 to 15 parts of hemlock parsley, 10 to 30 parts of tree peony bark, 5 to 20 parts of loquat leaf, 5 to 20 parts of pinellia tuber, 10 to 40 parts of figwort root, 5 to 20 parts of dried ginger, 5 to 15 parts of fructus amomi, 5 to 20 parts of cape jasmine, 5 to 15 parts of dwarf lilyturf tuber, 5 to 20 parts of cinnamon, 5 to 15 parts of astragalus, 10 to 40 parts of dogwood fruit pulp, 5 to 15 parts of glossy privet fruit, 5 to 15 parts of bletilla, 5 to 20 parts of baical skullcap root, and 5 to 15 parts of liquorice. The Chinese medicinal composition has the functions of clearing heat and purging fire, nourishing yin and promoting appetite, removing toxicity and curing furuncles, and diminishing swelling and promoting granulation, has the advantages of remarkable curative effect and reliable effect in treating recurrent oral ulcer, is wide in medicinal component source and easy to prepare, and does not have toxic or side effect.

Description

A kind of Chinese medicine composition for the treatment of recurrent oral ulceration

Technical field

The present invention relates to a kind of medicinal preparation of not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of recurrent oral ulceration.

Background technology

Recurrent oral ulceration, is called again " aphtha ", is a kind of taking outbreak periodically repeatedly as the oral mucosa limitation ulcerative lesions of feature, can spontaneous recovery, can occur in any position of oral mucosa., there is single or multiple circular or oval ulcer differing in size in the mucosa of locating with lip, cheek, soft palate or the gums etc. in oral cavity, the greyish white or blue pseudomembrane ulcer of surface coverage, and clear border, around mucosa is red and micro-swollen, and local causalgia is principal character.It easily recurs, the cycle is short, and very easily infects, as treatment not in time, and Relapse rate outbreak, it is lasting to delay, and also can transfer to " behcet's syndrome ", even involves internal organs, has caused great misery to patient's work and life.The recurrent oral ulceration cause of disease is more complicated, and clinical treatment will be according to different inducements, treatment pointedly, the curative effect that could obtain.As: remove psychentonia pressure, calmness, sleep peacefully, smoking cessation, wine etc.; For ulcer part, can adopt part to embrocate pain relieving, antiinflammatory, promotes the medicine healing.As: cod-liver oil paste, prednisone paste, nourishing yin shengjisan, ulcer ointment etc., or local anaesthetics is embrocated in front part on the feed, to ease the pain; Or adopt hormone and the antibiotic therapy misery with respite patient, but the infringement that the toxic and side effects such as the dysbacteriosis easily forming cause health.

The traditional Chinese medical science is thought: feelings will is unsuccessful and undermine heart spleen; Hyperactivity of fire caused by deficiency of YIN, pyretic toxicity is burnt bright, inner clip is damp and hot, on steam in mouth and the above-mentioned all diseases that arrive.Diseases caused by exogenous pathogenic factor six climate exopathogens dryness-fire, interior impairment of ZANG FU-organs intenseness of heat is the main cause of causing a disease, the dirty heart and the spleen of being of main disease.

According to theory of Chinese medical science, for the pathogeny of recurrent oral ulceration, taking heat clearing and damp drying, tonifying-Yin and nourishing-stomach, clearing away heart-fire as Therapeutic Principle, carry out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.

Summary of the invention

In order to overcome the deficiencies in the prior art, the invention provides a kind ofly prepare conveniently, medicine source is wide, cost is low, the Chinese medicine composition of evident in efficacy, reliable effect, the treatment recurrent oral ulceration that has no side effect.

The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of recurrent oral ulceration, it is characterized in that: its raw material of Chinese medicine by following weight portion proportioning forms: Rhizoma Picrorhizae 10-30 part, Cortex Phellodendri 5-20 part, Flos Lonicerae 5-15 part, Cortex Moutan 10-30 part, Folium Eriobotryae 5-20 part, Rhizoma Pinelliae 5-20 part, Radix Scrophulariae 10-40 part, Rhizoma Zingiberis 5-20 part, Fructus Amomi 5-15 part, Fructus Gardeniae 5-20 part, Radix Ophiopogonis 5-15 part, Cortex Cinnamomi 5-20 part, Radix Astragali 5-15 part, Fructus Corni 10-40 part, Fructus Ligustri Lucidi 5-15 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-15 part, Radix Scutellariae 5-20 part, Radix Glycyrrhizae 5-15 part.

The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of recurrent oral ulceration, is characterized in that: its raw material of Chinese medicine by following weight portion proportioning forms: 20 parts of Rhizoma Picrorhizae, 15 parts of Cortex Phellodendris, 10 parts of Flos Loniceraes, 25 parts of Cortex Moutans, 15 parts of Folium Eriobotryaes, 15 parts of the Rhizoma Pinelliaes, 30 parts of Radix Scrophulariaes, 15 parts of Rhizoma Zingiberiss, 10 parts of Fructus Amomis, 15 parts of Fructus Gardeniaes, 10 parts of Radix Ophiopogonis, 12 parts of Cortex Cinnamomis, 10 parts of the Radixs Astragali, 30 parts of Fructus Corni, 8 parts of Fructus Ligustri Lucidi, 10 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of Radix Scutellariaes, 8 parts, Radix Glycyrrhizae.

Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected medicament composing prescription.In Chinese medicine composition of the present invention: Rhizoma Picrorhizae has reducing the asthenic fever, effect of the infantile malnutrition with fever that disappears, heat clearing and damp drying, eliminating fire and detoxication; Cortex Phellodendri has heat clearing and damp drying, pathogenic fire purging except steaming, effect of detoxification sore treatment; Flos Lonicerae has effect of heat-clearing and toxic substances removing, wind-heat dissipating; Cortex Moutan has effect of clearing away heat and cooling blood, promoting blood circulation to remove blood stasis; Folium Eriobotryae has effect of lung heat clearing stomach function regulating, lowering the adverse-rising QI to resolve phlegm; The Rhizoma Pinelliae has drying dampness to eliminate phlegm, effect of stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass; Radix Scrophulariae has effect of removing heat from blood YIN nourishing, eliminating fire and detoxication; Rhizoma Zingiberis has that warming spleen and stomach for dispelling cold, recuperating depleted YANG are promoted blood circulation, effect of warming the lung to resolve fluid-retention; Fructus Amomi has removing dampness appetizing, warming spleen and stopping diarrha, the antiabortive effect of regulating the flow of vital energy;

Fructus Gardeniae has effect of pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body; There is effect that YIN nourishing and the production of body fluid promoting, lung moistening clear away heart-fire Radix Ophiopogonis; Cortex Cinnamomi has the effect of mending supporing yang, the dispersing cold for relieving pain of fire, promoting blood circulation to restore menstrual flow; The Radix Astragali has that benefiting QI for strengthening the superficies, tonifying the lung spleen invigorating, arresting sweating are admittedly de-, wind dispelling is transported malicious effect; Fructus Corni has effect of invigorating the liver and kidney, arresting seminal emission gas, solid collapse; Fructus Ligustri Lucidi has the merit that nourishing the liver and kidney, tonifying YIN nourish blood; The Pseudobulbus Bletillae (Rhizoma Bletillae) has effect of astringing to arrest bleeding, detumescence and promoting granulation; Radix Scutellariae has effect of heat clearing and damp drying, eliminating fire and detoxication, arresting bleeding and miscarriage prevention; Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.Drug component in the present composition is through dialectical compatibility, complements each other using, and has synergism, plays altogether effect of clearing away heat-fire, YIN nourishing appetizing, detoxification sore treatment, detumescence and promoting granulation, recurrent oral ulceration reached to the object for the treatment of both the principal and secondary aspects of a disease.

The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.It follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopt the use that is decocted in water for oral dose.Through clinical practice checking, it is evident in efficacy, reliable effect, and the property of medicine is gentle, does not occur toxic and side effects, total effective rate 94.8%, cure rate reaches 38.4%.

Detailed description of the invention

Below in conjunction with embodiment, the present invention will be further described.

Embodiment 1

Treat a Chinese medicine composition for recurrent oral ulceration, its raw material of Chinese medicine by following weight proportion forms: Rhizoma Picrorhizae 20g, Cortex Phellodendri 15g, Flos Lonicerae 10g, Cortex Moutan 25g, Folium Eriobotryae 15g, Rhizoma Pinelliae 15g, Radix Scrophulariae 30g, Rhizoma Zingiberis 15g, Fructus Amomi 10g, Fructus Gardeniae 15g, Radix Ophiopogonis 10g, Cortex Cinnamomi 12g, Radix Astragali 10g, Fructus Corni 30g, Fructus Ligustri Lucidi 8g, Pseudobulbus Bletillae (Rhizoma Bletillae) 10g, Radix Scutellariae 15g, Radix Glycyrrhizae 8g.

Embodiment 2

Treat a Chinese medicine composition for recurrent oral ulceration, its raw material of Chinese medicine by following weight proportion forms: Rhizoma Picrorhizae 15g, Cortex Phellodendri 20g, Flos Lonicerae 5g, Cortex Moutan 15g, Folium Eriobotryae 10g, Rhizoma Pinelliae 20g, Radix Scrophulariae 10g, Rhizoma Zingiberis 12g, Fructus Amomi 5g, Fructus Gardeniae 20g, Radix Ophiopogonis 5g, Cortex Cinnamomi 20g, Radix Astragali 5g, Fructus Corni 20g, Fructus Ligustri Lucidi 5g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Radix Scutellariae 5g, Radix Glycyrrhizae 10g.

Embodiment 3

Treat a Chinese medicine composition for recurrent oral ulceration, its raw material of Chinese medicine by following weight proportion forms: Rhizoma Picrorhizae 10g, Cortex Phellodendri 15g, Flos Lonicerae 12g, Cortex Moutan 20g, Folium Eriobotryae 8g, Rhizoma Pinelliae 5g, Radix Scrophulariae 40g, Rhizoma Zingiberis 10g, Fructus Amomi 15g, Fructus Gardeniae 10g, Radix Ophiopogonis 15g, Cortex Cinnamomi 10g, Radix Astragali 15g, Fructus Corni 25g, Fructus Ligustri Lucidi 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 8g, Radix Scutellariae 20g, Radix Glycyrrhizae 5g.

Embodiment 4

Treat a Chinese medicine composition for recurrent oral ulceration, its raw material of Chinese medicine by following weight proportion forms: Rhizoma Picrorhizae 30g, Cortex Phellodendri 10g, Flos Lonicerae 8g, Cortex Moutan 30g, Folium Eriobotryae 5g, Rhizoma Pinelliae 10g, Radix Scrophulariae 20g, Rhizoma Zingiberis 5g, Fructus Amomi 8g, Fructus Gardeniae 12g, Radix Ophiopogonis 8g, Cortex Cinnamomi 5g, Radix Astragali 20g, Fructus Corni 10g, Fructus Ligustri Lucidi 15g, Pseudobulbus Bletillae (Rhizoma Bletillae) 12g, Radix Scutellariae 10g, Radix Glycyrrhizae 15g.

Embodiment 5

Treat a Chinese medicine composition for recurrent oral ulceration, its raw material of Chinese medicine by following weight proportion forms: Rhizoma Picrorhizae 25g, Cortex Phellodendri 5g, Flos Lonicerae 15g, Cortex Moutan 10g, Folium Eriobotryae 20g, Rhizoma Pinelliae 12g, Radix Scrophulariae 15g, Rhizoma Zingiberis 20g, Fructus Amomi 12g, Fructus Gardeniae 5g, Radix Ophiopogonis 15g, Cortex Cinnamomi 15g, Radix Astragali 8g, Fructus Corni 40g, Fructus Ligustri Lucidi 12g, Pseudobulbus Bletillae (Rhizoma Bletillae) 5g, Radix Scutellariae 12g, Radix Glycyrrhizae 12g.

Chinese medicine composition in embodiment of the present invention decocting method is routinely produced medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, add cold water and cover powder, soak 15～20 minutes, then add water and do not have approximately 8 centimetres of powder, decoct.At a simmer, adopt intense fire to decoct, after boiling, use slow fire boiling 20～30 minutes; Second decocts, and adds water and does not have approximately 6 centimetres of powder, after water boils, decocts 15～20 minutes.Twice decoction extracting juice that removes slag, merges.

Treat a Chinese medicine composition for recurrent oral ulceration, clinical efficacy is summed up:

One, general data: this Chinese medicine composition is applied to clinical observation case 98 examples, wherein male 46 examples, female's 52 examples, 15～65 years old age.The shortest person of the course of disease 2 days, elder reaches 60 days, average 8 days.

Two, diagnostic criteria:

1, the ulcer that occurs single or several diameter 3～5mm with oral mucosa, scorching hot pain is cardinal symptom;

2, onset is very fast, healing in general about 7 days, if down here, the course of disease extends.More normal easily recurrence after;

3, examination of mouth: stomatocace is shown shallow, circular or oval, 1～2 at least of quantity, more than 10 at most, surface has faint yellow secretions to adhere to, and ulcer around mucosa is mostly congested.

Three, usage and dosage: when clinical practice, the amounts of components in compositions is taken the circumstances into consideration increase and decrease according to patient's body weight, age and symptom.Within five days, be a course for the treatment of, one day potion, the about 400ml of twice extracting juice of decocting, point early, late twice half an hour ante cibum warm taking.The thing that period in a medicine avoids pungent food, stimulates.

Four, criterion of therapeutical effect:

1, cure: oral ulcer healing, local without sense of discomfort;

2, take a turn for the better: although there is recurrence when aphtha, quantity reduces, and degree alleviates;

3, do not heal: aphtha symptom and ulcer are without significant change.

Five, therapeutic effect: in this clinical observation case, take medicine 1-6 the course for the treatment of, cure 67 examples, 26 examples that take a turn for the better, 5 examples do not heal.During treatment, there is not toxic and side effects.

Six, model case:

Case 1:

Yuan, female, 42 years old, body of the tongue was light red, and there is indentation on both sides, and there is many places ulcer on oral cavity palate and tongue both sides, not of uniform size, micro-red.Pulse condition is superficially and silly soft.Vexed not peaceful, diet is subject to certain influence because mouth aches, defecate slightly half congealed, and eumenorrhea, remaining disease of obviously giving prominence to without other.Take 1 course for the treatment of of medicament prepared by Chinese medicine composition of the present invention, symptom disappears substantially, aphtha healing residue small size ulcer; Continue to strengthen 2 courses for the treatment of, all symptoms all disappear, and cure.

Case 2:

Willow, man, 17 years old, pain in mouthful, xerostomia, feverish sensation in the palms and soles.2 of aphthas, diameter is less than 0.5 centimetre, slight congested around.Red tongue, tongue is few, thready and rapid pulse.Take 1 course for the treatment of of medicament prepared by Chinese medicine composition of the present invention, aphtha area diminishes, and xerostomia is improved; Continue and take 1 course for the treatment of, symptom all disappears, recovery from illness.

Claims

1. a Chinese medicine composition for the treatment of recurrent oral ulceration, is characterized in that: its raw material of Chinese medicine by following weight proportion forms: Rhizoma Picrorhizae 20g, Cortex Phellodendri 15g, Flos Lonicerae 10g, Cortex Moutan 25g, Folium Eriobotryae 15g, Rhizoma Pinelliae 15g, Radix Scrophulariae 30g, Rhizoma Zingiberis 15g, Fructus Amomi 10g, Fructus Gardeniae 15g, Radix Ophiopogonis 10g, Cortex Cinnamomi 12g, Radix Astragali 10g, Fructus Corni 30g, Fructus Ligustri Lucidi 8g, Pseudobulbus Bletillae (Rhizoma Bletillae) 10g, Radix Scutellariae 15g, Radix Glycyrrhizae 8g.