CN116322582A - 用于向眼部组织输送药物的系统和方法 - Google Patents

用于向眼部组织输送药物的系统和方法 Download PDF

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Publication number
CN116322582A
CN116322582A CN202180069308.XA CN202180069308A CN116322582A CN 116322582 A CN116322582 A CN 116322582A CN 202180069308 A CN202180069308 A CN 202180069308A CN 116322582 A CN116322582 A CN 116322582A
Authority
CN
China
Prior art keywords
needle
distal
tip
adapter
sclera
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202180069308.XA
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English (en)
Chinese (zh)
Inventor
布莱恩·格里格斯
马修·鲍斯利
梅根·德雷德
佩奇·韦克特
普里特维·辛格
罗斯·凯尼恩
西比盖特·乌拉
崔佛·兰利
比比安·伊格莱希亚斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Regeneron Pharmaceuticals Inc
Original Assignee
Regeneron Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharmaceuticals Inc filed Critical Regeneron Pharmaceuticals Inc
Publication of CN116322582A publication Critical patent/CN116322582A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0026—Ophthalmic product dispenser attachments to facilitate positioning near the eye
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3403—Needle locating or guiding means
    • A61B2017/3405—Needle locating or guiding means using mechanical guide means

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Prostheses (AREA)
CN202180069308.XA 2020-08-12 2021-08-11 用于向眼部组织输送药物的系统和方法 Pending CN116322582A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063064658P 2020-08-12 2020-08-12
US63/064,658 2020-08-12
PCT/US2021/071164 WO2022036367A1 (en) 2020-08-12 2021-08-11 Systems and methods for drug delivery to ocular tissue

Publications (1)

Publication Number Publication Date
CN116322582A true CN116322582A (zh) 2023-06-23

Family

ID=77951887

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180069308.XA Pending CN116322582A (zh) 2020-08-12 2021-08-11 用于向眼部组织输送药物的系统和方法

Country Status (11)

Country Link
US (1) US20220047420A1 (https=)
EP (1) EP4196060A1 (https=)
JP (2) JP7756706B2 (https=)
KR (1) KR20230045073A (https=)
CN (1) CN116322582A (https=)
AU (1) AU2021325994A1 (https=)
BR (1) BR112023002465A2 (https=)
CA (1) CA3188860A1 (https=)
IL (1) IL300377A (https=)
MX (1) MX2023001752A (https=)
WO (1) WO2022036367A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230405238A1 (en) 2022-06-17 2023-12-21 Regeneron Pharmaceuticals, Inc. Systems and methods for drug delivery to ocular tissue
TW202539597A (zh) 2023-11-08 2025-10-16 美商再生元醫藥公司 用於眼部組織之藥物遞送的系統及方法
EP4674393A1 (en) * 2024-07-04 2026-01-07 Carl Zeiss Meditec AG Needle and needle system for subretinal injection

Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050085791A1 (en) * 2003-09-17 2005-04-21 Shaw Sharon M. Disinfectant, antibiotic and anesthetic containing device for injections and incisions
US20110152749A1 (en) * 2008-03-14 2011-06-23 Institut National De La Sante Et De La Recherche Medicale Eye injection device
US20110238038A1 (en) * 2008-12-04 2011-09-29 Nanopass Technologies Ltd. Intradermal mini - needle interface and associated devices and methods
WO2012051575A2 (en) * 2010-10-15 2012-04-19 Iscience Interventional Corporation Device for ocular access
US20150051581A1 (en) * 2013-05-03 2015-02-19 Clearside Biomedical, Inc. Apparatus and methods for ocular injection
WO2015196085A2 (en) * 2014-06-20 2015-12-23 Clearside Biomedical, Inc. Variable diameter cannula and methods for controlling insertion depth for medicament delivery
US20160074211A1 (en) * 2014-09-11 2016-03-17 Ethicon Endo-Surgery, Inc. Therapeutic agent delivery device with advanceable cannula and needle
CN105592828A (zh) * 2013-08-02 2016-05-18 堤乐哈修门医学研究基础建设及服务有限公司 用于将组合物递送至眼睛的装置
GB201619904D0 (en) * 2016-11-24 2017-01-11 Salar Surgical Ltd Positioning device and method
US20170303940A1 (en) * 2016-04-26 2017-10-26 Boston Scientific Limited Percutaneous access device with adjustable depth stop
WO2018111862A1 (en) * 2016-12-15 2018-06-21 Clearside Biomedical, Inc. Systems and methods for delivering drugs to retinal tissue
WO2019172940A1 (en) * 2018-03-09 2019-09-12 Aquesys, Inc. Intraocular shunt inserter

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108290004A (zh) * 2015-11-18 2018-07-17 福尔密孔股份公司 含有vegf拮抗剂的预填充塑料注射器

Patent Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050085791A1 (en) * 2003-09-17 2005-04-21 Shaw Sharon M. Disinfectant, antibiotic and anesthetic containing device for injections and incisions
US20110152749A1 (en) * 2008-03-14 2011-06-23 Institut National De La Sante Et De La Recherche Medicale Eye injection device
US20110238038A1 (en) * 2008-12-04 2011-09-29 Nanopass Technologies Ltd. Intradermal mini - needle interface and associated devices and methods
WO2012051575A2 (en) * 2010-10-15 2012-04-19 Iscience Interventional Corporation Device for ocular access
CN103327939A (zh) * 2010-10-15 2013-09-25 I科学干预公司 用于进入眼睛的装置
US20150051581A1 (en) * 2013-05-03 2015-02-19 Clearside Biomedical, Inc. Apparatus and methods for ocular injection
CN105592828A (zh) * 2013-08-02 2016-05-18 堤乐哈修门医学研究基础建设及服务有限公司 用于将组合物递送至眼睛的装置
WO2015196085A2 (en) * 2014-06-20 2015-12-23 Clearside Biomedical, Inc. Variable diameter cannula and methods for controlling insertion depth for medicament delivery
US20160074211A1 (en) * 2014-09-11 2016-03-17 Ethicon Endo-Surgery, Inc. Therapeutic agent delivery device with advanceable cannula and needle
US20170303940A1 (en) * 2016-04-26 2017-10-26 Boston Scientific Limited Percutaneous access device with adjustable depth stop
GB201619904D0 (en) * 2016-11-24 2017-01-11 Salar Surgical Ltd Positioning device and method
WO2018111862A1 (en) * 2016-12-15 2018-06-21 Clearside Biomedical, Inc. Systems and methods for delivering drugs to retinal tissue
WO2019172940A1 (en) * 2018-03-09 2019-09-12 Aquesys, Inc. Intraocular shunt inserter

Also Published As

Publication number Publication date
JP2025188129A (ja) 2025-12-25
US20220047420A1 (en) 2022-02-17
MX2023001752A (es) 2023-02-22
AU2021325994A1 (en) 2023-03-09
KR20230045073A (ko) 2023-04-04
JP7756706B2 (ja) 2025-10-20
CA3188860A1 (en) 2022-02-17
IL300377A (en) 2023-04-01
JP2023537962A (ja) 2023-09-06
WO2022036367A1 (en) 2022-02-17
EP4196060A1 (en) 2023-06-21
BR112023002465A2 (pt) 2023-03-28

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