CN116286363A - 用于培养细胞的器皿 - Google Patents

用于培养细胞的器皿 Download PDF

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Publication number
CN116286363A
CN116286363A CN202310452756.9A CN202310452756A CN116286363A CN 116286363 A CN116286363 A CN 116286363A CN 202310452756 A CN202310452756 A CN 202310452756A CN 116286363 A CN116286363 A CN 116286363A
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China
Prior art keywords
vessel
cells
deformable portion
cell culture
incubator
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Pending
Application number
CN202310452756.9A
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English (en)
Chinese (zh)
Inventor
A·布兰查德
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Thrive Bioscience Inc
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Thrive Bioscience Inc
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Publication of CN116286363A publication Critical patent/CN116286363A/zh
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/08—Flask, bottle or test tube
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/29—Mixing by periodically deforming flexible tubular members through which the material is flowing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/30—Mixers with shaking, oscillating, or vibrating mechanisms comprising a receptacle to only a part of which the shaking, oscillating, or vibrating movement is imparted
    • B01F31/31—Mixers with shaking, oscillating, or vibrating mechanisms comprising a receptacle to only a part of which the shaking, oscillating, or vibrating movement is imparted using receptacles with deformable parts, e.g. membranes, to which a motion is imparted
    • B01F31/311—Mixers with shaking, oscillating, or vibrating mechanisms comprising a receptacle to only a part of which the shaking, oscillating, or vibrating movement is imparted using receptacles with deformable parts, e.g. membranes, to which a motion is imparted the motion being a linear movement to one part of the receptacle
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/26—Constructional details, e.g. recesses, hinges flexible
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02—Stirrer or mobile mixing elements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B60—VEHICLES IN GENERAL
    • B60G—VEHICLE SUSPENSION ARRANGEMENTS
    • B60G2202/00—Indexing codes relating to the type of spring, damper or actuator
    • B60G2202/40—Type of actuator
    • B60G2202/42—Electric actuator
    • B60G2202/424—Electric actuator electrostrictive materials, e.g. piezoelectric actuator
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements
    • G01N2035/00356—Holding samples at elevated temperature (incubation)

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Immunology (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN202310452756.9A 2016-04-12 2017-04-12 用于培养细胞的器皿 Pending CN116286363A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662321691P 2016-04-12 2016-04-12
US62/321,691 2016-04-12
CN201780036445.7A CN109642208A (zh) 2016-04-12 2017-04-12 用于培养细胞的器皿
PCT/US2017/027239 WO2017180762A1 (en) 2016-04-12 2017-04-12 Vessel for culturing cells

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201780036445.7A Division CN109642208A (zh) 2016-04-12 2017-04-12 用于培养细胞的器皿

Publications (1)

Publication Number Publication Date
CN116286363A true CN116286363A (zh) 2023-06-23

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Family Applications (2)

Application Number Title Priority Date Filing Date
CN202310452756.9A Pending CN116286363A (zh) 2016-04-12 2017-04-12 用于培养细胞的器皿
CN201780036445.7A Pending CN109642208A (zh) 2016-04-12 2017-04-12 用于培养细胞的器皿

Family Applications After (1)

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CN201780036445.7A Pending CN109642208A (zh) 2016-04-12 2017-04-12 用于培养细胞的器皿

Country Status (5)

Country Link
US (2) US20210214665A1 (cg-RX-API-DMAC7.html)
EP (1) EP3475412A4 (cg-RX-API-DMAC7.html)
JP (5) JP7531201B2 (cg-RX-API-DMAC7.html)
CN (2) CN116286363A (cg-RX-API-DMAC7.html)
WO (1) WO2017180762A1 (cg-RX-API-DMAC7.html)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116286363A (zh) * 2016-04-12 2023-06-23 兴盛生物科技股份有限公司 用于培养细胞的器皿
WO2020014188A1 (en) * 2018-07-09 2020-01-16 The Regents Of The University Of Michigan Microscope surveillance system
CN110343614A (zh) * 2019-06-10 2019-10-18 中国科学院深圳先进技术研究院 一种刺激细胞生长的体外培养装置
EP4001396A1 (en) * 2020-11-17 2022-05-25 Bühler AG Device for treating cells in a bypass
CN112322495B (zh) * 2020-12-08 2025-03-18 泉州伟业生物医学科技有限公司 一种细胞培养装置及细胞培养方法
WO2022165411A1 (en) * 2021-02-01 2022-08-04 Thrive Bioscience, Inc. Plaque detection method for imaging of cells
JP7642060B2 (ja) * 2021-03-15 2025-03-07 本田技研工業株式会社 培養装置
CN115747009B (zh) * 2022-11-18 2023-04-21 青岛中仁澳兰生物工程有限公司 一种病毒悬浮培养装置
KR102905190B1 (ko) * 2023-11-02 2025-12-26 이준범 스티어 바를 이용한 3차원 동작 배양 접시 및 이를 포함하는 기계적 배양 시스템
TWI899003B (zh) * 2025-02-11 2025-09-21 美榮生醫股份有限公司 多功能大型細胞培養室

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH658071A5 (de) * 1981-12-29 1986-10-15 Spofa Vereinigte Pharma Werke Verfahren zur kultivierung von zellen hoeherer organismen und einrichtung zur durchfuehrung dieses verfahrens.
JPH01124379A (ja) * 1987-11-06 1989-05-17 Shimadzu Corp 培養装置
CN1882681A (zh) * 2003-11-18 2006-12-20 雀巢技术公司 细胞培养系统
US20090111179A1 (en) * 2005-11-01 2009-04-30 Norihiko Hata Cell Culture Shaking Device and Shaking Culture Method as Cell Culture Method
US20120003709A1 (en) * 2010-07-01 2012-01-05 Empire Technology Development Llc. Method and system for cell and tissue cultivation
CN104818214A (zh) * 2015-04-23 2015-08-05 浙江大学 一种智能培养皿
US20160108352A1 (en) * 2013-07-10 2016-04-21 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Culture vessel and method for culturing biological cells in hanging drops
JP2017046591A (ja) * 2014-01-09 2017-03-09 東京エレクトロン株式会社 細胞培養システムおよび細胞の剥離方法
US20200239825A1 (en) * 2017-10-19 2020-07-30 Koninklijke Philips N.V. Cell preservation or culturing arrangment

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JPS63173576A (ja) * 1987-01-14 1988-07-18 Ebara Res Co Ltd 培養装置
JPS6423884A (en) * 1987-07-17 1989-01-26 Ebara Res Co Ltd Culture apparatus
US5686301A (en) * 1993-09-02 1997-11-11 Heraeus Instruments Gmbh Culture vessel for cell cultures
DE19644761C1 (de) * 1996-10-29 1998-02-05 Heraeus Instr Gmbh Zellkulturerntegerät
FR2821853B1 (fr) * 2001-03-09 2003-05-16 Natural Implant Sa Bioreacteur pour tissu cultive en couche mince et utilisations
GB0410177D0 (en) * 2004-05-07 2004-06-09 Univ Wales Medicine Engineered tubular tissue structures
WO2007044690A2 (en) * 2005-10-07 2007-04-19 The General Hospital Corporation Devices and methods for cell manipulation
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PL2951452T3 (pl) * 2013-02-01 2017-03-31 ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN BIOMATERIALES - CIC biomaGUNE Układ mieszania nieintruzywnego
US11802265B2 (en) * 2015-06-25 2023-10-31 Auckland Uniservices Ltd Tissue culture apparatus and method
CN116286363A (zh) 2016-04-12 2023-06-23 兴盛生物科技股份有限公司 用于培养细胞的器皿

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH658071A5 (de) * 1981-12-29 1986-10-15 Spofa Vereinigte Pharma Werke Verfahren zur kultivierung von zellen hoeherer organismen und einrichtung zur durchfuehrung dieses verfahrens.
JPH01124379A (ja) * 1987-11-06 1989-05-17 Shimadzu Corp 培養装置
CN1882681A (zh) * 2003-11-18 2006-12-20 雀巢技术公司 细胞培养系统
US20090111179A1 (en) * 2005-11-01 2009-04-30 Norihiko Hata Cell Culture Shaking Device and Shaking Culture Method as Cell Culture Method
US20120003709A1 (en) * 2010-07-01 2012-01-05 Empire Technology Development Llc. Method and system for cell and tissue cultivation
US20160108352A1 (en) * 2013-07-10 2016-04-21 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Culture vessel and method for culturing biological cells in hanging drops
JP2017046591A (ja) * 2014-01-09 2017-03-09 東京エレクトロン株式会社 細胞培養システムおよび細胞の剥離方法
CN104818214A (zh) * 2015-04-23 2015-08-05 浙江大学 一种智能培养皿
US20200239825A1 (en) * 2017-10-19 2020-07-30 Koninklijke Philips N.V. Cell preservation or culturing arrangment

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Publication number Publication date
JP7531201B2 (ja) 2024-08-09
JP2019511230A (ja) 2019-04-25
JP7548611B2 (ja) 2024-09-10
WO2017180762A1 (en) 2017-10-19
US20220403314A1 (en) 2022-12-22
JP2022060542A (ja) 2022-04-14
EP3475412A4 (en) 2020-03-18
US20210214665A1 (en) 2021-07-15
JP2024092020A (ja) 2024-07-05
CN109642208A (zh) 2019-04-16
EP3475412A1 (en) 2019-05-01
JP2023158061A (ja) 2023-10-26
JP2023063427A (ja) 2023-05-09

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