CN116270292A - Composition for regulating scalp microecological balance and preparation method and application thereof - Google Patents
Composition for regulating scalp microecological balance and preparation method and application thereof Download PDFInfo
- Publication number
- CN116270292A CN116270292A CN202310199080.7A CN202310199080A CN116270292A CN 116270292 A CN116270292 A CN 116270292A CN 202310199080 A CN202310199080 A CN 202310199080A CN 116270292 A CN116270292 A CN 116270292A
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- scalp
- composition
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- microecological balance
- conditioner
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
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- A—HUMAN NECESSITIES
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Botany (AREA)
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- Cosmetics (AREA)
Abstract
The application relates to the field of cosmetics, and in particular discloses a composition for regulating scalp microecological balance, which comprises the following components in parts by mass: 0.2-0.6 part of hydrolyzed yeast protein; 0.05-0.1 part of alpha glucan oligosaccharide; inulin 0.1-0.56 part; 0.05-0.2 part of lactobacillus/soybean milk fermentation product filtrate; 0.2-0.36 parts of conditioner; the conditioner comprises madecassoside and centella asiatica extract. The scalp microecological balance regulating composition can be added into shampoo, hair conditioner or hair cream. The application has the effects of strengthening the barrier function of scalp horny layer, regulating the lipid content of scalp, optimizing the moisture content of scalp, obviously reducing scalp allergies such as desquamation, itch and the like, is also beneficial to improving the ecological environment of scalp, recovering the balance of scalp flora, and has the effects of improving the repetition of dandruff and scalp sensitization without depending on the traditional antibacterial antidandruff agent.
Description
Technical Field
The application relates to the field of cosmetics, in particular to a composition for regulating scalp microecological balance, a preparation method and application thereof.
Background
The scalp is a unique niche compared to the skin elsewhere in the human body and is characterized by dense hair, a large number of sweat glands, sebaceous glands and high relative humidity. Meanwhile, the detached keratinocytes, mineral ions generated by sweat gland secretion, lipids generated by sebaceous gland secretion and the like provide rich nutrition sources for microorganisms. The above features of the scalp create suitable conditions for the colonization and growth of microorganisms. The microbiota of the normal scalp is mainly composed of bacteria and fungi, wherein the bacterial flora is mainly staphylococcus aureus and staphylococcus epidermidis, and the fungi microorganism is mainly malassezia. Studies have shown that malassezia on the scalp account for 96% of the total fungi, with limiting malassezia and malassezia globosa being the major dominant species.
At present, most of anti-dandruff cosmetics on the market use various antifungal drugs as main efficacy components to reduce the growth of scalp microorganisms, inhibit the transitional division of scalp keratinocytes, reduce the speed of epidermal regeneration and prevent the cells to be shed from accumulating into macroscopic massive scales, thereby achieving the purpose of anti-dandruff.
However, the anti-dandruff product has no obvious effect on dandruff caused by dysbacteriosis of scalp, has large irritation and is easy to damage skin. Thus, there is still room for improvement.
Disclosure of Invention
The composition for regulating scalp microecological balance, the preparation method and the application thereof have the effects of strengthening scalp cuticle barrier function, regulating lipid content of scalp, optimizing scalp moisture content, obviously reducing scalp allergy such as desquamation, itching and the like, are beneficial to improving scalp ecological environment, recovering scalp flora balance, and achieve the effects of improving scalp recurrence and scalp susceptibility without depending on the traditional antibacterial anti-dandruff agent.
In a first aspect, the present application provides a composition for regulating scalp microecological balance, which adopts the following technical scheme:
a composition for regulating scalp microecological balance comprises the following components in parts by weight:
0.2-0.6 part of hydrolyzed yeast protein;
0.05-0.1 part of alpha glucan oligosaccharide;
inulin 0.1-0.56 part;
0.05-0.2 part of lactobacillus/soybean milk fermentation product filtrate;
0.2-0.36 parts of conditioner;
the conditioner comprises madecassoside and centella asiatica extract.
By adopting the technical scheme, the hydrolyzed yeast protein can control oil and resist seborrhea, relieve the problem of vigorous oil secretion, regulate and control the ratio of staphylococcus aureus to staphylococcus epidermidis, improve the skin environment, promote the recovery of skin barrier and strengthen the skin defenses; alpha glucan and inulin have the effects of rapidly controlling the proliferation of harmful germs and supplementing prebiotic substances of beneficial germs; the lactobacillus/soybean milk fermentation product filtrate can balance scalp microbiota, improve the level of antibacterial peptide and restore healthy scalp barrier; madecassoside and centella asiatica extract can regulate keratinocyte differentiation, and restore excessive keratinization state.
Therefore, by adopting the synergistic combination of hydrolyzed yeast protein, alpha glucan, inulin, lactobacillus/soybean milk fermentation product filtrate, madecassoside and centella asiatica extract, not only can the skin lipid synthesis be promoted and the scalp hydration be increased, but also the differentiation of keratinocytes can be regulated, and the problems of scalp dryness, fine white scraps and the like caused by the damage of the barrier of the scalp can be improved. Meanwhile, the ratio of staphylococcus aureus to staphylococcus epidermidis can be regulated, and the increase of harmful flora such as malassezia is limited, so that the effects of improving the ecological environment of the scalp and recovering the balance of the flora of the scalp are achieved.
Preferably, the composition for regulating scalp microecological balance comprises the following components in parts by mass:
0.3-0.4 parts of hydrolyzed yeast protein;
0.06-0.08 part of alpha glucan oligosaccharide;
inulin 0.2-0.4 parts;
0.08-0.14 part of lactobacillus/soybean milk fermentation product filtrate;
0.25-0.33 parts of conditioner.
Preferably, the mass ratio of the hydrolyzed yeast protein, alpha glucan, inulin, lactobacillus/soybean milk fermentation product filtrate, madecassoside and centella asiatica extract is 0.5:0.08:0.3:0.13:0.19:0.01.
by adopting the technical scheme, the hydrolyzed yeast protein, alpha glucan, inulin, lactobacillus/soybean milk fermentation product filtrate, madecassoside and centella asiatica extract with specific proportions are adopted to cooperatively cooperate, so that the scalp microecological balance is further regulated, the healthy scalp microecology is maintained, and the effect of reducing scalp microbial infection is achieved.
Preferably, the conditioning agent further comprises one or more of hydroxyphenylpropionamide benzoic acid, heptapeptide-6, and dipotassium glycyrrhizinate.
By adopting the technical scheme, the hydroxyphenyl propionamide benzoic acid can inhibit the activity of NK1 receptor and block the release of histamine which causes itching, thereby quickly relieving scalp itching; heptapeptide-6 has the same binding as EGE and activates EGF receptor activity, and can promote skin cell proliferation; dipotassium glycyrrhizinate can reduce the quantity of granulocytes, reduce wound inflammatory response and accelerate tissue wound healing.
Therefore, by adopting the synergistic combination of any one of the hydroxyphenylpropionyl-benzoic acid, the heptapeptide-6 and the dipotassium glycyrrhizinate with hydrolyzed yeast protein, alpha glucan, inulin, lactobacillus/soybean milk fermentation product filtrate, madecassoside and centella asiatica extract, the scalp allergy problems such as desquamation, itching and the like can be obviously reduced.
Preferably, the conditioner further comprises a combination of hydroxyphenylpropionamide benzoic acid, heptapeptide-6 and dipotassium glycyrrhizinate.
Preferably, the mass ratio of the hydroxyphenyl propionamide benzoic acid to the heptapeptide-6 to the dipotassium glycyrrhizinate is 0.006:0.0003:0.15.
by adopting the technical scheme, the synergistic combination of the hydroxyphenyl propionamide benzoic acid, the heptapeptide-6 and the dipotassium glycyrrhizinate with the hydrolyzed yeast protein, the alpha glucan, the inulin, the lactobacillus/soybean milk fermentation product filtrate, the madecassoside and the centella asiatica extract in a specific proportion can achieve the long-acting and non-repeated anti-dandruff itching relieving effects, quickly decompose the excessive scalp grease and improve the seborrheic dermatitis.
In a second aspect, the present application provides a method for preparing a composition for regulating scalp microecological balance, which adopts the following technical scheme:
a preparation method of a composition for regulating scalp microecological balance comprises the following steps:
respectively adding hydrolyzed yeast protein, alpha glucan, inulin, lactobacillus/soybean milk fermentation product filtrate, madecassoside and centella asiatica extract into a stirring kettle, and uniformly mixing to obtain the composition for regulating scalp microecological balance.
By adopting the technical scheme, the composition for regulating scalp microecology balance is prepared by adopting the method, is simple and convenient, and is beneficial to industrial production.
In a third aspect, the present application provides an application of a composition for regulating scalp microecological balance, which adopts the following technical scheme:
a composition for regulating scalp microecological balance can be added into shampoo, hair conditioner or hair cream.
In summary, the present application includes at least one of the following beneficial technical effects:
1. by adopting the synergistic combination of hydrolyzed yeast protein, alpha glucan, inulin, lactobacillus/soybean milk fermentation product filtrate, madecassoside and centella asiatica extract, the preparation not only can promote skin lipid synthesis and increase scalp hydration, but also can regulate keratinocyte differentiation, and can solve the problems of scalp dryness, fine white scraps and the like caused by damaged scalp barrier. Meanwhile, the ratio of staphylococcus aureus to staphylococcus epidermidis can be regulated, and the increase of harmful flora such as malassezia is limited, so that the effects of improving the ecological environment of the scalp and recovering the balance of the flora of the scalp are achieved.
2. The hydrolyzed yeast protein, alpha glucan, inulin, lactobacillus/soybean milk fermentation product filtrate, madecassoside and centella asiatica extract are adopted in a specific proportion to cooperatively cooperate, so that the scalp microecological balance is further regulated, the healthy scalp microecology is maintained, and the scalp microbial infection is reduced.
3. By adopting the synergistic compounding of the hydroxyphenyl propionamide benzoic acid, the heptapeptide-6 and the dipotassium glycyrrhizinate in a specific proportion with hydrolyzed yeast protein, alpha glucan, inulin, lactobacillus/soybean milk fermentation product filtrate, madecassoside and centella asiatica extract, the effects of long-acting and non-repeated anti-dandruff itching relieving can be achieved, the superfluous scalp grease can be rapidly decomposed, and the seborrheic dermatitis can be improved.
Detailed Description
The present application is described in further detail below with reference to examples.
Example 1
The embodiment discloses a composition for regulating scalp microecological balance, which comprises the following components:
hydrolyzing yeast protein; alpha glucan oligosaccharides; inulin; lactobacillus/soymilk fermentation product filtrate; a conditioning agent; the conditioner comprises madecassoside and centella asiatica extract.
The embodiment also discloses a preparation method of the composition for regulating scalp microecological balance, which comprises the following steps:
respectively adding hydrolyzed yeast protein, alpha glucan, inulin, lactobacillus/soybean milk fermentation product filtrate, madecassoside and herba Centellae extract into stirring kettle according to table 1, and mixing at 50r/min to obtain composition for regulating scalp microecological balance.
Examples 2 to 5
The difference from example 1 is that: the amounts of the components are different.
The amounts of the components used in examples 1 to 5 are shown in Table 1, and the unit of the amounts used in Table 1 is kg.
TABLE 1
Example 6
The difference from example 2 is that: the conditioner also comprises the compound of the hydroxyphenylpropionamide benzoic acid, the heptapeptide-6 and the dipotassium glycyrrhizinate, and the mass ratio of the hydroxyphenylpropionamide benzoic acid to the heptapeptide-6 to the dipotassium glycyrrhizinate is 0.006:0.0003:0.15.
example 7
The difference from example 6 is that: equal amounts of hydroxyphenylpropionamide benzoic acid were used in place of heptapeptide-6.
Example 8
The difference from example 6 is that: equal amount of hydroxy phenyl propionamide benzoic acid is used for replacing dipotassium glycyrrhizinate.
Example 9
The difference from example 6 is that: equal amounts of heptapeptide-6 were substituted for the hydroxyphenylpropionamide benzoic acid.
Comparative example 1
The difference from example 2 is that: the alpha glucan oligosaccharides were replaced with an equal amount of hydrolyzed yeast protein.
Comparative example 2
The difference from example 2 is that: inulin was replaced with an equal amount of hydrolysed yeast protein.
Comparative example 3
The difference from example 2 is that: the lactobacillus/soymilk fermentation product filtrate was replaced with an equal amount of hydrolyzed yeast protein.
Comparative example 4
The difference from example 2 is that: equal amounts of hydrolyzed yeast protein were used instead of madecassoside.
Comparative example 5
The difference from example 2 is that: the centella asiatica extract is replaced by an equivalent amount of hydrolyzed yeast protein.
Comparative example 6
The difference from example 2 is that: the amounts of the components are different.
A composition for regulating scalp microecological balance, which comprises the following components in mass:
0.1kg of hydrolyzed yeast protein; 0.03kg of alpha glucan oligosaccharides; inulin 0.6kg; 0.02kg of lactobacillus/soybean milk fermentation product filtrate; 0.46kg of conditioner.
Experimental example 1
The shampoo comprises the following components in mass:
phase A: 94.73kg of water; 2.0kg of 1, 2-pentanediol; 0.4kg of p-hydroxyacetophenone;
and B phase: 1.2kg of water; 0.28kg of butanediol; 0.15kg of 1, 2-pentanediol; trehalose 0.03kg; sodium dihydrogen phosphate 0.0007kg; disodium hydrogen phosphate 0.0002kg; ascorbyl palmitate 0.0002kg; 1.21kg of the scalp microecological balance regulating composition prepared in example 1 was used.
A preparation method of shampoo comprises the following steps:
s1: respectively adding the components in the phase A into an emulsifying pot, stirring at 35HZ, heating to 80 ℃, fully and uniformly stirring, and stirring at constant temperature for 15min;
s2: cooling to 40deg.C, sequentially adding the components in phase B into emulsifying pot, stirring at 35Hz for 3min, and stirring thoroughly; and after preliminary inspection, filtering and discharging with 400-mesh filter cloth to obtain the shampoo.
Experimental example 2
The difference from experimental example 1 is that: the composition for regulating scalp microecological balance prepared in example 2 was used.
Experimental example 3
The difference from experimental example 1 is that: the composition for regulating scalp microecological balance prepared in example 3 was used.
Experimental example 4
The difference from experimental example 1 is that: the scalp microecological balance regulating composition prepared in example 4 was used.
Experimental example 5
The difference from experimental example 1 is that: the composition for regulating scalp microecological balance prepared in example 5 was used.
Experimental example 6
The difference from experimental example 1 is that: the composition for regulating scalp microecological balance prepared in example 6 was used.
Experimental example 7
The difference from experimental example 1 is that: the scalp microecological balance regulating composition prepared in example 7 was used.
Experimental example 8
The difference from experimental example 1 is that: the composition for regulating scalp microecological balance prepared in example 8 was used.
Experimental example 9
The difference from experimental example 1 is that: the scalp microecological balance regulating composition prepared in example 9 was used.
Comparative experiment example 1
The difference from experimental example 1 is that: the composition for regulating scalp microecological balance prepared in comparative example 1 was used.
Comparative experiment example 2
The difference from experimental example 1 is that: the composition for regulating scalp microecological balance prepared in comparative example 2 was used.
Comparative experiment example 3
The difference from experimental example 1 is that: the composition for regulating scalp microecological balance prepared in comparative example 3 was used.
Comparative experiment example 4
The difference from experimental example 1 is that: the composition for regulating scalp microecological balance prepared in comparative example 4 was used.
Comparative experiment example 5
The difference from experimental example 1 is that: the composition for regulating scalp microecological balance was prepared by using the composition for regulating scalp microecological balance prepared in comparative example 5.
Comparative experiment example 6
The difference from experimental example 1 is that: the composition for regulating scalp microecological balance prepared in comparative example 6 was used.
Experiment 1 Performance test
TABLE 2
As shown in table 2, the shampoo prepared by the method has excellent anti-dandruff and antipruritic effects, and can meet basic detection requirements.
Experiment 2 bacteriostasis experiment
The bacteriostasis test mainly adopts a bacteriostasis circle method to test the bacteriostasis effect of the shampoo on staphylococcus aureus, staphylococcus epidermidis and limiting malassezia, and the specific test method comprises the following steps:
(1) Activating strains: staphylococcus aureus, staphylococcus epidermidis and limiting malassezia preserved in a refrigerator at 4 ℃ are transferred to a fresh nutrient agar slope and cultured for 18-24 hours at 37 ℃.
(2) Preparation of bacterial suspension: washing lawn on the inclined plane with 10mL sterilized physiological saline twice, placing into conical flask containing glass beads, shaking on shaking table at 200r/min for 10min, and adjusting bacterial suspension concentration to 10 6 cfu/ml。
(3) Preparation of a bacteriostatic flat plate: each test tube is divided into 20ml of melted nutrient agar culture medium, redundant culture medium at the mouth of the test tube is wiped off by paper towels, a rubber plug is added, 7 test tubes are bundled and bound up, sterilization is carried out for 20min at 121 ℃, and the test tubes are placed in a constant-temperature water bath kettle at 50 ℃ for heat preservation after being slightly cooled after sterilization. On an ultra-clean workbench, 1mL of bacterial suspension is added into each sterilization culture dish, 20mL of culture dishes are poured into each sterilization culture dish, and the sterilization culture dishes are fully and uniformly mixed, and condensed water is dried and solidified.
(4) Oxford cup method: the sterilized oxford cup is clamped out by sterile forceps, is firstly placed on the flame of an alcohol lamp to quickly pass through fire, and then is vertically placed on the surface of a culture medium, and is lightly pressed, so that no gap exists between the bottom of the cup and the culture medium. Placing 5 oxford cups on each flat plate, injecting 200uL of shampoo into each oxford cup, and using normal saline as a contrast in the middle, wherein the shampoo cannot overflow; each shampoo was repeated 3 times, incubated at 37℃for 24 hours, and the diameter (mm) of the inhibition zone was recorded by observation and measurement, and the experimental results are shown in Table 3.
TABLE 3 Table 3
According to the data of comparative examples 1 to 5 in Table 3, which are obtained by comparing with example 1, respectively, the comparative example 1 was free of alpha glucan oligosaccharides, the comparative example 2 was free of inulin, the comparative example 3 was free of lactobacillus/soymilk fermentation product filtrate, the comparative example 4 was free of madecassoside, the comparative example 5 was free of centella asiatica extract, the shampoo had a smaller diameter of the area of the shampoo against staphylococcus aureus than that of example 1, and the shampoo had a smaller diameter of the area of the shampoo against staphylococcus epidermidis than that of example 1, respectively, which indicated that the absence of any of hydrolyzed yeast protein, alpha glucan, inulin, lactobacillus/soymilk fermentation product filtrate, madecassoside and centella asiatica extract could not simultaneously enhance the inhibitory effect of shampoo against staphylococcus aureus, staphylococcus epidermidis and staphylococcus aureus. Only by adopting the synergistic combination of hydrolyzed yeast protein, alpha glucan, inulin, lactobacillus/soybean milk fermentation product filtrate, madecassoside and centella asiatica extract, the inhibition effect of shampoo on staphylococcus aureus, staphylococcus epidermidis and limiting malassezia can be enhanced, so that the effects of improving the ecological environment of scalp and restoring the balance of scalp flora are achieved.
According to the comparison of comparative experiment example 6 and experiment example 1 in Table 3, the proportion of hydrolyzed yeast protein, alpha glucan, inulin, lactobacillus/soybean milk fermentation product filtrate, madecassoside and centella asiatica extract in comparative experiment example 6 is not within the scope protected by the application, and the inhibition effect of shampoo in comparative experiment example 6 on staphylococcus aureus, staphylococcus epidermidis and limited malassezia is not as good as that of experiment example 1, which shows that the proportion of hydrolyzed yeast protein, alpha glucan, inulin, lactobacillus/soybean milk fermentation product filtrate, madecassoside and centella asiatica extract can be enhanced simultaneously only within the scope protected by the application, thereby achieving the effect of rapidly relieving itching and removing dandruff.
Experiment 3 human sensory evaluation
And qualitatively and quantitatively measuring and analyzing the characteristics of different dimensions of the shampoo by sense organs. After the volunteers with scalp problems such as scalp itch and dandruff are recruited into groups, the volunteers are randomly grouped, each group is 10, each group of volunteers respectively test 1 shampoo, the shampoo is washed once every two days and is continuously used for 8 weeks, a tester carries out evaluation scoring (1-10 scores) according to the anti-dandruff and itching relieving effects, average scores are taken, and experimental results are shown in table 4.
TABLE 4 Table 4
According to the comparison of comparative examples 1 to 5 in Table 4 with experimental example 1, it is possible to obtain shampoo with excellent anti-dandruff and antipruritic effects by employing synergistic combination of hydrolyzed yeast protein, alpha glucan, inulin, lactobacillus/soybean milk fermentation product filtrate, madecassoside and centella asiatica extract, and to rapidly decompose excessive scalp grease and improve seborrheic dermatitis.
According to the experimental examples 7-9 in Table 4, which are respectively compared with the experimental example 6, the experimental example 6 adopts the synergistic combination of the hydroxyphenylpropionyl benzoic acid, the heptapeptide-6 and the dipotassium glycyrrhizinate with the hydrolyzed yeast protein, the alpha glucan, the inulin, the lactobacillus/soybean milk fermentation product filtrate, the madecassoside and the centella asiatica extract, so that the scalp allergy problems such as desquamation, itching and the like can be obviously reduced, and people have better experience.
The foregoing are all preferred embodiments of the present application, and are not intended to limit the scope of the present application in any way, therefore: all equivalent changes in structure, shape and principle of this application should be covered in the protection scope of this application.
Claims (8)
1. A composition for regulating scalp microecological balance, characterized in that: comprises the following components in parts by mass:
0.2-0.6 part of hydrolyzed yeast protein;
0.05-0.1 part of alpha glucan oligosaccharide;
inulin 0.1-0.56 part;
0.05-0.2 part of lactobacillus/soybean milk fermentation product filtrate;
0.2-0.36 parts of conditioner;
the conditioner comprises madecassoside and centella asiatica extract.
2. A composition for regulating scalp microecological balance according to claim 1, wherein: the composition for regulating scalp microecological balance comprises the following components in parts by mass:
0.3-0.4 parts of hydrolyzed yeast protein;
0.06-0.08 part of alpha glucan oligosaccharide;
inulin 0.2-0.4 parts;
0.08-0.14 part of lactobacillus/soybean milk fermentation product filtrate;
0.25-0.33 parts of conditioner.
3. A composition for regulating scalp microecological balance according to claim 1, wherein: the mass ratio of the hydrolyzed yeast protein, alpha glucan, inulin, lactobacillus/soybean milk fermentation product filtrate, madecassoside and centella asiatica extract is 0.5:0.08:0.3:0.13:0.19:0.01.
4. a composition for regulating scalp microecological balance according to claim 1, wherein: the conditioner also comprises one or more of hydroxy phenyl propionamide benzoic acid, heptapeptide-6 and dipotassium glycyrrhizinate.
5. A composition for regulating the microecological balance of the scalp according to claim 4, wherein: the conditioner also comprises the compound of hydroxy phenyl propionamide benzoic acid, heptapeptide-6 and dipotassium glycyrrhizinate.
6. A composition for regulating the microecological balance of the scalp according to claim 5, wherein: the mass ratio of the hydroxyphenyl propionamide benzoic acid to the heptapeptide-6 to the dipotassium glycyrrhizinate is 0.006:0.0003:0.15.
7. a method of preparing a composition for regulating scalp microecological balance as set forth in any one of claims 1 to 6, characterized in that: the method comprises the following steps:
respectively adding hydrolyzed yeast protein, alpha glucan, inulin, lactobacillus/soybean milk fermentation product filtrate, madecassoside and centella asiatica extract into a stirring kettle, and uniformly mixing to obtain the composition for regulating scalp microecological balance.
8. Use of a composition for regulating the microecological balance of the scalp as claimed in any one of claims 1 to 6, characterized in that: it can be added into shampoo, hair conditioner or hair cream.
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