CN116251052A - Head care product for preventing hair loss, fixing hair and moisturizing scalp and preparation method thereof - Google Patents

Head care product for preventing hair loss, fixing hair and moisturizing scalp and preparation method thereof Download PDF

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Publication number
CN116251052A
CN116251052A CN202310287450.2A CN202310287450A CN116251052A CN 116251052 A CN116251052 A CN 116251052A CN 202310287450 A CN202310287450 A CN 202310287450A CN 116251052 A CN116251052 A CN 116251052A
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hair
parts
component
moisturizing
fixing
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刘伟
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Guangzhou Meisi Biotechnology Co ltd
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Guangzhou Meisi Biotechnology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/645Proteins of vegetable origin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9755Gymnosperms [Coniferophyta]
    • A61K8/9761Cupressaceae [Cypress family], e.g. juniper or cypress
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/12Preparations containing hair conditioners
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00Preparations for affecting hair growth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52Stabilizers
    • A61K2800/524Preservatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/78Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782Enzyme inhibitors; Enzyme antagonists
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

The invention discloses a head care product for preventing hair loss, fixing hair and moistening scalp, which comprises the following raw materials in parts by weight: 5-10 parts of matrix component, 4-8 parts of liposome component, 5-15 parts of anti-hair loss and hair fixing moisturizing component, 0.5-2 parts of moisturizing and antioxidant component, 0.5-2 parts of preservative component and 100 parts of deionized water, wherein the liposome component is a human skin stem cell factor nanoliposome complex; the invention treats the active ingredients by using the nano lipid encapsulation technology, has the advantage of strengthening the permeability of the active ingredients, can provide multiple nutrition for hair follicle growth by adding the anti-hair-fixing and moisturizing component, inhibit the activity of 5 alpha-reductase, prevent the production of dihydrotestosterone, enable the active ingredients to reach the hair follicle as soon as possible, promote the transition of telogen hair to developmental stage, prevent alopecia, help the normal growth of hair, and achieve the effects of hair growth and alopecia prevention.

Description

Head care product for preventing hair loss, fixing hair and moisturizing scalp and preparation method thereof
Technical Field
The invention relates to the technical field of cosmetics, in particular to a head care product capable of preventing hair loss, fixing hair and moistening scalp and a preparation method thereof.
Background
The hair-care product has the advantages of dense, black and bright hair, attractive, elegant and tidy hair style, and can not only enable people to be set in a bright and beautiful appearance, but also be a sign of body health, so that the protection and modification of the hair are very important for men, women, old and young in the past. Protecting and decorating hair requires scientific use of some hair care products in addition to frequent grooming and keeping clean.
Hair loss is common in men, computer workers and people with excessive pressure, and various diseases of hair and daily nursing are also caused by hair injury or hair dryness, bifurcation and falling, so that the appearance and spirit of people are affected to different degrees. Normally, hair that is normally shed is hair in the catagen and catagen phases, and the hair that enters the catagen phase and the catagen phase is in dynamic balance, so that normal number of hairs can be maintained, while pathological alopecia refers to abnormal or excessive hair loss, which is caused by various reasons including endocrine dyscrasia, mental trauma, vascular dysfunction, inheritance, and the like. With the increase of learning and working pressure and the acceleration of life rhythm, the problem of alopecia becomes one of the main problems facing people in the society today.
Maintenance of hair quality is noted in general for hair care, but most people ignore scalp care. If the hair care is not carried out, the hair loss, the vigorous secretion of grease, the dandruff problem, the itching, the allergy and the like are all known to occur easily. If the hair follicle is damaged and is in a "pseudo-death" state, nutrients cannot be absorbed from the scalp, hair bulb cells are notified to grow up and begin to shrink, and the hair becomes thin, yellow and withered. After the follicle has degenerated and atrophied, the hair will stop growing and gradually wilt off. Therefore, the invention provides a head care product for preventing hair loss, fixing hair and moistening scalp and a preparation method thereof.
Disclosure of Invention
Aiming at the defects of the prior art, the invention aims to provide a head care product for preventing hair loss, fixing hair and moisturizing scalp and a preparation method thereof, so as to solve the problems in the background art.
The invention solves the technical problems by adopting the following technical scheme:
the invention provides a head care product for preventing hair loss, fixing hair and moistening scalp, which comprises the following raw materials in parts by weight: 5-10 parts of matrix component, 4-8 parts of liposome component, 5-15 parts of hair loss prevention and hair fixation moisturizing component, 0.5-2 parts of moisturizing and antioxidant component, 0.5-2 parts of preservative component and 100 parts of deionized water;
the liposome component is a human skin stem cell factor nanoliposome complex;
the anti-drop hair-fixing and moisturizing component comprises the following raw materials in parts by weight: 1-5 parts of cacumen biotae extract, 1-5 parts of saw palmetto extract, 1-5 parts of caffeine, 1-5 parts of red ball ginger extract, 1-5 parts of maifang pepperweed root extract and 1-5 parts of flos rosae multiflorae extract.
The cacumen Platycladi extract is mainly hot water extract of cacumen Platycladi, has the effects of removing local grease and improving local blood circulation, and can relieve grease at scalp and promote scalp blood circulation by washing hair with cacumen Platycladi, and has certain treatment and alleviation effects on seborrheic dermatitis of head or alopecia due to head.
Saw palmetto extract: in addition, the saw palms can not only reduce the DHT around the prostate, but also have a reducing effect on the DHT content of a plurality of tissues of a human body, and naturally also comprise scalp, so that the problem of hair loss of people can be improved.
Caffeine: the cause of AGA is mainly dihydrotestosterone, testosterone can be said to be a first hair follicle killer, caffeine can resist the invasion of DHT to hair papilla, has some effects of promoting hair growth, hair loss is most likely to occur on forehead and top of head, the resistance of the parts to the hair follicle killer DHT is poor, and caffeine can improve the problem and is obtained through purchase.
The zingiber zerumbet is a plant of the genus zingiber of the family zingiberaceae, which is produced in taiwan, guangdong, guangxi and other places in China and is widely planted in southeast Asia countries. The red ball ginger oil can be used as a raw material of the blending essence. The chemical components comprise zerumbone, humulone, kaempferol glucoside and the like. Has strong proliferation promoting effect on hair follicle cells, thereby promoting hair growth.
The Lepidium meyenii root extract is derived from the mountain plateau of Peruvian Andies, and the multi-angle test proves that the component has excellent capability of strengthening and strengthening hair and enhancing the growth speed of the hair, and is obtained through purchase.
Flos Rosae Multiflorae is plant of Rosa of Rosaceae, and is produced around the world. Flos Rosae Multiflorae contains abundant volatile oil and flavonoid compounds including esters, alcohols, phenols, astragalin, etc. The flos Rosae Multiflorae extract has good antibacterial activity, and can promote melanocyte, and is a good hair blackening and hair growth promoting agent.
Preferably, the matrix component comprises the following raw materials in parts by weight: 1-3 parts of lanolin, 0.05-0.1 part of EDTA-2Na, 0.2-2 parts of magnesium stearate, 0.2-0.6 part of pentasodium tripolyphosphate, 0.2-0.6 part of hydroxyethyl cellulose and 0.1-0.5 part of citric acid fatty glyceride.
Preferably, the moisturizing and antioxidation component comprises the following raw materials in parts by weight: 1-5 parts of hydrolyzed zein, 1-3 parts of PCA zinc, 0.5-2 parts of cystine, 0.5-2 parts of cysteine and 0.1-1 part of xylitol.
Xylitol has strong water locking performance, and micromolecular xylitol can strengthen the elasticity of hair by penetrating into the hair, so that the hair is moist and full of vigor; cystine is an important component of the skin layers and the outer keratin layers of the hair, can enhance the mechanical rigidity and chemical elasticity of the hair, slow down the swelling of damaged hair in water, and the xylitol and cystine synergistically enhance the strength and toughness of the hair through moisturizing and regulating effects.
Preferably, the anti-corrosion component comprises the following raw materials in parts by weight: 0.05-0.1 part of piroctone olamine, 0.05-0.2 part of p-hydroxyacetophenone and 0.05-0.3 part of biotin.
The hydrolyzed zein is prepared from collagen polypeptide (protein) by enzyme engineering, and has various human metabolism and physiological regulation functions, and is easy to digest and absorb, and can promote scalp position recovery and repair, improve proliferation of follicular orifice position, and avoid injury of follicular orifice position
The structure of PCA zinc is a major component in the stratum corneum of the skin and is one of the natural moisturizing factors. The PCA zinc converts sodium ions in the natural moisturizing factors into zinc ions with antibacterial effect, and simultaneously provides moisturizing effect and excellent antibacterial performance for skin. Numerous scientific studies have shown that zinc can reduce sebum hypersecretion by inhibiting 5-a reductase
Preferably, 0.1-0.5 parts of a perfume component is also included.
Preferably, the essence component is one or a mixture of two of lavender oil and apple ester.
The invention also provides application of the head care product for preventing hair loss, fixing hair and moistening scalp in cosmetics, wherein the head care product is scalp essence, scalp massage cream, shampoo, hair mask and hair conditioner.
The invention also provides a preparation method of the head care product for preventing hair loss, fixing hair and moistening scalp, which comprises the following steps:
weighing the matrix component, the liposome component, the anti-hair loss and hair fixing moisturizing component, the moisturizing and antioxidant component, the preservative component and deionized water;
adding deionized water and matrix components into a reaction kettle, heating and stirring to completely dissolve solid phase matters of the matrix components, continuously stirring at constant temperature for 20-30min, slowly cooling and standing to obtain a mixture A;
step three, adding the anti-drop hair-fixing moisturizing component and the moisturizing and antioxidant component into the mixture A while stirring when the temperature of the mixture A is reduced to 40-50 ℃, stirring at constant temperature for 20-30min, uniformly dispersing, and cooling to obtain a mixture B;
sequentially adding a liposome component, a preservative component and an essence component into the mixture B prepared in the step three, and stirring at constant temperature by ultrasonic until the components are uniformly dispersed to obtain inclusion solution;
and fifthly, adding deionized water into the inclusion solution to fill up to 100 parts, uniformly stirring, standing for 10-20min, filtering and discharging to obtain the head care product for preventing hair loss, fixing hair and moistening scalp.
Preferably, the heating and stirring method in the second step is to heat to 75-85 ℃ at 5-10 ℃/min, mechanically stir at 50-100r/min, and slowly cool at 3-5 ℃/min.
Preferably, the cooling temperature of the mixture B in the third step is reduced to 32-38 ℃, the ultrasonic frequency in the fourth step is 25000-30000Hz, and the ultrasonic time is 10-20min.
Compared with the prior art, the invention has the following beneficial effects:
the invention treats the active ingredients by using the nano lipid encapsulation technology, has the advantage of strengthening the permeability of the active ingredients, can provide multiple nutrition for hair follicle growth by adding the anti-hair-loss and hair-fixing moisturizing component, inhibit 5 alpha-reductase activity, prevent dihydrotestosterone from generating, prevent androgenic alopecia, stimulate the signal expression of hair follicle growth factors, quickly activate hair follicles, dredge capillaries of scalp, enable the active ingredients to reach the hair follicles as soon as possible, promote the transition of telogen hair to developmental stage, prevent alopecia, help hair to grow normally, and achieve the effects of hair growth and alopecia prevention.
The shampoo has the effects of helping foaming, improving foam stability, improving the solubility of the base material surfactant, generating pearlescence for the shampoo, smoothing and smoothing the hair and preventing or reducing the insoluble substances of the calcium-magnesium soap from being deposited on the hair when the shampoo is washed by hard water through the added matrix component, the moisturizing and antioxidant component and the preservative component.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are only some, but not all embodiments of the invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
The invention provides a head care product for preventing hair loss, fixing hair and moisturizing scalp, which comprises the following raw materials in parts by weight: 5-10 parts of matrix component, 4-8 parts of liposome component, 5-15 parts of hair loss prevention and hair fixation moisturizing component, 0.5-2 parts of moisturizing and antioxidant component, 0.5-2 parts of preservative component and 100 parts of deionized water;
the liposome component is a human skin stem cell factor nanoliposome complex;
the anti-hair loss and hair fixing moisturizing component comprises the following raw materials in parts by weight: 1-5 parts of cacumen biotae extract, 1-5 parts of saw palmetto extract, 1-5 parts of caffeine, 1-5 parts of red ball ginger extract, 1-5 parts of maifang pepperweed root extract and 1-5 parts of flos rosae multiflorae extract.
The matrix component of the embodiment comprises the following raw materials in parts by weight: 1-3 parts of lanolin, 0.05-0.1 part of EDTA-2Na, 0.2-2 parts of magnesium stearate, 0.2-0.6 part of pentasodium tripolyphosphate, 0.2-0.6 part of hydroxyethyl cellulose and 0.1-0.5 part of citric acid fatty glyceride.
The moisturizing and antioxidant component of the embodiment comprises the following raw materials in parts by weight: 1-5 parts of hydrolyzed zein, 1-3 parts of PCA zinc, 0.5-2 parts of cystine, 0.5-2 parts of cysteine and 0.1-1 part of xylitol.
The anti-corrosion component of the embodiment comprises the following raw materials in parts by weight: 0.05-0.1 part of piroctone olamine, 0.05-0.2 part of p-hydroxyacetophenone and 0.05-0.3 part of biotin.
The present embodiment also includes 0.1-0.5 parts of a fragrance component.
The essence component of this embodiment is a mixture of one or both of lavender oil and apple ester.
The embodiment also provides a preparation method of the head care product for preventing hair loss, fixing hair and moisturizing scalp, which comprises the following steps:
weighing the matrix component, the liposome component, the anti-hair loss and hair fixing moisturizing component, the moisturizing and antioxidant component, the preservative component and deionized water;
adding deionized water and matrix components into a reaction kettle, heating and stirring to completely dissolve solid phase matters of the matrix components, continuously stirring at constant temperature for 20-30min, slowly cooling and standing to obtain a mixture A;
step three, adding the anti-drop hair-fixing moisturizing component and the moisturizing and antioxidant component into the mixture A while stirring when the temperature of the mixture A is reduced to 40-50 ℃, stirring at constant temperature for 20-30min, uniformly dispersing, and cooling to obtain a mixture B;
sequentially adding a liposome component, a preservative component and an essence component into the mixture B prepared in the step three, and stirring at constant temperature by ultrasonic until the components are uniformly dispersed to obtain inclusion solution;
and fifthly, adding deionized water into the inclusion solution to fill up to 100 parts, uniformly stirring, standing for 10-20min, filtering and discharging to obtain the head care product for preventing hair loss, fixing hair and moistening scalp.
The heating and stirring method in the second step of the embodiment is to heat to 75-85 ℃ at 5-10 ℃/min, mechanically stir at 50-100r/min, slowly cool down and cool down at 3-5 ℃/min.
In the third step of the embodiment, the cooling temperature of the mixture B is reduced to 32-38 ℃, the ultrasonic frequency in the fourth step is 25000-30000Hz, and the ultrasonic time is 10-20min.
Example 1.
The invention provides a head care product for preventing hair loss, fixing hair and moisturizing scalp, which comprises the following raw materials in parts by weight: 5 parts of matrix component, 4 parts of liposome component, 5 parts of anti-drop hair-fixing and moisturizing component, 0.5 part of moisturizing and antioxidant component, 0.5 part of preservative component and 100 parts of deionized water;
the liposome component is a human skin stem cell factor nanoliposome complex;
the anti-hair loss and hair fixing moisturizing component comprises the following raw materials in parts by weight: 1 part of cacumen biotae extract, 1 part of saw palmetto extract, 1 part of caffeine, 1 part of zingiber zerumbet extract, 1 part of maifanitum root extract and 1 part of flos rosae multiflori extract.
The matrix component of the embodiment comprises the following raw materials in parts by weight: 1 part of lanolin, 0.05 part of EDTA-2Na, 0.2 part of magnesium stearate, 0.2 part of pentasodium tripolyphosphate, 0.2 part of hydroxyethyl cellulose and 0.1 part of citric acid fatty glyceride.
The moisturizing and antioxidant component of the embodiment comprises the following raw materials in parts by weight: 1 part of hydrolyzed corn protein, 1 part of PCA zinc, 0.5 part of cystine, 0.5 part of cysteine and 0.1 part of xylitol.
The anti-corrosion component of the embodiment comprises the following raw materials in parts by weight: 0.05 part of piroctone olamine salt, 0.05 part of p-hydroxyacetophenone and 0.05 part of biotin.
This example also includes 0.1 parts of a fragrance component.
The essence component of this example is lavender oil.
The embodiment also provides a preparation method of the head care product for preventing hair loss, fixing hair and moisturizing scalp, which comprises the following steps:
weighing the matrix component, the liposome component, the anti-hair loss and hair fixing moisturizing component, the moisturizing and antioxidant component, the preservative component and deionized water;
adding deionized water and matrix components into a reaction kettle, heating and stirring to completely dissolve solid phase matters of the matrix components, continuously stirring at constant temperature for 20min, slowly cooling and standing to obtain a mixture A;
step three, adding the anti-drop hair-fixing moisturizing component and the moisturizing and antioxidant component into the mixture A while stirring when the temperature of the mixture A is reduced to 40 ℃, stirring at constant temperature for 20min, uniformly dispersing, and cooling to obtain a mixture B;
sequentially adding a liposome component, a preservative component and an essence component into the mixture B prepared in the step three, and stirring at constant temperature by ultrasonic until the components are uniformly dispersed to obtain inclusion solution;
and fifthly, adding deionized water into the inclusion solution to fill up to 100 parts, uniformly stirring, standing for 10min, filtering and discharging to obtain the head care product for preventing hair loss, fixing hair and moistening scalp.
The heating and stirring method in the second step of the embodiment is to heat to 75 ℃ at 5 ℃/min, mechanically stir at 50r/min, slowly cool down and cool down at 3 ℃/min.
In the third step of this example, the cooling temperature of the mixture B was reduced to 32℃and in the fourth step, the ultrasonic frequency was 25000Hz and the ultrasonic time was 10min.
Example 2.
The invention provides a head care product for preventing hair loss, fixing hair and moisturizing scalp, which comprises the following raw materials in parts by weight: 10 parts of matrix component, 8 parts of liposome component, 15 parts of anti-drop hair-fixing and moisturizing component, 2 parts of moisturizing and antioxidant component, 2 parts of preservative component and 100 parts of deionized water;
the liposome component is a human skin stem cell factor nanoliposome complex;
the anti-hair loss and hair fixing moisturizing component comprises the following raw materials in parts by weight: 5 parts of cacumen biotae extract, 5 parts of saw palmetto extract, 5 parts of caffeine, 5 parts of zingiber zerumbet extract, 5 parts of maifanitum root extract and 5 parts of flos rosae multiflori extract.
The matrix component of the embodiment comprises the following raw materials in parts by weight: 3 parts of lanolin, 0.1 part of EDTA-2Na, 2 parts of magnesium stearate, 0.6 part of pentasodium tripolyphosphate, 0.6 part of hydroxyethyl cellulose and 0.5 part of citric acid fatty glyceride.
The moisturizing and antioxidant component of the embodiment comprises the following raw materials in parts by weight: 5 parts of hydrolyzed zein, 3 parts of PCA zinc, 2 parts of cystine, 2 parts of cysteine and 1 part of xylitol.
The anti-corrosion component of the embodiment comprises the following raw materials in parts by weight: 0.1 part of piroctone olamine salt, 0.2 part of p-hydroxyacetophenone and 0.3 part of biotin.
This example also includes 0.5 parts of a fragrance component.
The perfume component of this example is malate.
The embodiment also provides a preparation method of the head care product for preventing hair loss, fixing hair and moisturizing scalp, which comprises the following steps:
weighing the matrix component, the liposome component, the anti-hair loss and hair fixing moisturizing component, the moisturizing and antioxidant component, the preservative component and deionized water;
adding deionized water and matrix components into a reaction kettle, heating and stirring to completely dissolve solid phase matters of the matrix components, continuously stirring at constant temperature for 30min, slowly cooling and standing to obtain a mixture A;
step three, adding the anti-drop hair-fixing moisturizing component and the moisturizing and antioxidant component into the mixture A while stirring when the temperature of the mixture A is reduced to 50 ℃, stirring at constant temperature for 30min, uniformly dispersing, and cooling to obtain a mixture B;
sequentially adding a liposome component, a preservative component and an essence component into the mixture B prepared in the step three, and stirring at constant temperature by ultrasonic until the components are uniformly dispersed to obtain inclusion solution;
and fifthly, adding deionized water into the inclusion solution to fill up to 100 parts, uniformly stirring, standing for 20min, filtering and discharging to obtain the head care product for preventing hair loss, fixing hair and moistening scalp.
The heating and stirring method in the second step of the embodiment is to heat to 85 ℃ at 10 ℃/min, mechanically stir at 100r/min, slowly cool down and cool down at 5 ℃/min.
In the third step of this example, the cooling temperature of the mixture B was reduced to 38deg.C, and in the fourth step, the ultrasonic frequency was 30000Hz and the ultrasonic time was 20min.
Example 3.
The invention provides a head care product for preventing hair loss, fixing hair and moisturizing scalp, which comprises the following raw materials in parts by weight: 7.5 parts of matrix component, 6 parts of liposome component, 10 parts of anti-drop hair-fixing and moisturizing component, 12.5 parts of moisturizing and antioxidant component, 12.5 parts of preservative component and 100 parts of deionized water;
the liposome component is a human skin stem cell factor nanoliposome complex;
the anti-hair loss and hair fixing moisturizing component comprises the following raw materials in parts by weight: 3 parts of cacumen biotae extract, 3 parts of saw palmetto extract, 3 parts of caffeine, 3 parts of zingiber zerumbet extract, 3 parts of maifanitum root extract and 3 parts of flos rosae multiflori extract.
The matrix component of the embodiment comprises the following raw materials in parts by weight: 2 parts of lanolin, 0.07 part of EDTA-2Na, 1.1 part of magnesium stearate, 0.4 part of pentasodium tripolyphosphate, 0.4 part of hydroxyethyl cellulose and 0.3 part of citric acid fatty glyceride.
The moisturizing and antioxidant component of the embodiment comprises the following raw materials in parts by weight: 3 parts of hydrolyzed zein, 2 parts of PCA zinc, 0.13 part of cystine, 0.13 part of cysteine and 0.55 part of xylitol.
The anti-corrosion component of the embodiment comprises the following raw materials in parts by weight: 0.07 part of piroctone olamine salt, 1 part of p-hydroxyacetophenone and 0.17 part of biotin.
This example also includes 0.3 parts of a fragrance component.
The essence component of this example is a blend of lavender oil and malate.
The embodiment also provides a preparation method of the head care product for preventing hair loss, fixing hair and moisturizing scalp, which comprises the following steps:
weighing the matrix component, the liposome component, the anti-hair loss and hair fixing moisturizing component, the moisturizing and antioxidant component, the preservative component and deionized water;
adding deionized water and matrix components into a reaction kettle, heating and stirring to completely dissolve solid phase matters of the matrix components, continuously stirring at constant temperature for 25min, slowly cooling and standing to obtain a mixture A;
step three, adding the anti-drop hair-fixing moisturizing component and the moisturizing and antioxidant component into the mixture A while stirring when the temperature of the mixture A is reduced to 45 ℃, stirring at constant temperature for 25min, uniformly dispersing, and cooling to obtain a mixture B;
sequentially adding a liposome component, a preservative component and an essence component into the mixture B prepared in the step three, and stirring at constant temperature by ultrasonic until the components are uniformly dispersed to obtain inclusion solution;
and fifthly, adding deionized water into the inclusion solution to be supplemented to 100 parts, uniformly stirring, standing for 15min, filtering and discharging to obtain the head care product for preventing hair loss, fixing hair and moistening scalp.
The heating and stirring method in the second step of the embodiment is to heat to 80 ℃ at 7 ℃/min, mechanically stir at 75r/min, slowly cool down and cool down at 4 ℃/min.
In the third step of the embodiment, the cooling temperature of the mixture B is reduced to 35 ℃, the ultrasonic frequency in the fourth step is 27500Hz, and the ultrasonic time is 15min.
Comparative example 1.
The difference from example 3 is that no cacumen Platycladi extract was added.
Comparative example 2.
The difference from example 3 is the extract of the saw palmetto.
Comparative example 3.
Unlike example 3, caffeine was not added.
Comparative example 4.
The difference from example 3 is the extract of non-red ball ginger.
Comparative example 5.
The difference from example 3 is that no mai-yin pepperweed root extract was added.
The products of examples 1-3 and comparative examples 1-5 were subjected to performance testing;
80 male volunteers with thin hair or loss were selected for testing, aged 25 to 55 years, with an average age of 40 years, and the 80 volunteers were randomly divided into 8 groups of 10. The hair care products prepared in examples 1 to 3 and comparative examples 1 to 5 were tested on 8 groups of volunteers each, with a frequency of 2 times per week. The volunteers perform smearing and massaging for 10-15 minutes after washing hair, and the volunteers are cleaned by clear water after all the volunteers absorb the hair. Each hair care product for preventing hair loss, fixing hair and moisturizing scalp was continuously used for 21 days, and volunteers scored examples and comparative examples according to their own experiences and tested for content of dihydrotestosterone in vivo for volunteers of different periods of time. The score was 10 minutes, 1 was the worst, 6 was moderate, and 10 was the best, the higher the score, the better the hair growth and hair care effect, and the results are shown in table 1.
TABLE 1
Figure SMS_1
As can be seen from examples 1-3; the head care product for preventing hair loss, fixing hair and moistening scalp prepared by the invention has remarkable effects of promoting hair growth speed, promoting hair follicle restoration and improving hair quality.
From comparative examples 1 to 5 and example 3, the hair growth rate, hair follicle restoration rate and hair quality improvement effect of example 3 are obviously better than those of comparative examples 1 to 5 through the compound use of each component in the anti-hair loss and hair fixing moisturizing component and reasonable component content;
in addition, compared with the head care products of examples 1-3 and comparative examples 1-5, the hair-loss preventing, hair-fixing and scalp-moistening product of the invention has obviously reduced dihydrotestosterone, and the shampoo prepared in examples 1-3 contains cacumen biotae extract, saw palmetto extract and caffeine, has obvious effect of inhibiting dihydrotestosterone, so that the problem of alopecia is solved from the aspect of root-derived persistent dioxytestosterone generation, and simultaneously has the functions of promoting hair growth, hair follicle restoration, improving hair quality, making hair more robust, resisting hair damage caused by ultraviolet rays and environmental pollution, improving hair growth environment and enhancing scalp resistance.
The innovation point of the invention is that:
the invention treats the active ingredients by using the nano lipid encapsulation technology, has the advantage of strengthening the permeability of the active ingredients, can provide multiple nutrition for hair follicle growth by adding the anti-hair-loss and hair-fixing moisturizing component, inhibit 5 alpha-reductase activity, prevent dihydrotestosterone from generating, prevent androgenic alopecia, stimulate the signal expression of hair follicle growth factors, quickly activate hair follicles, dredge capillaries of scalp, enable the active ingredients to reach the hair follicles as soon as possible, promote the transition of telogen hair to developmental stage, prevent alopecia, help hair to grow normally, and achieve the effects of hair growth and alopecia prevention.
The shampoo has the effects of helping foaming, improving foam stability, improving the solubility of the base material surfactant, generating pearlescence for the shampoo, smoothing and smoothing the hair and preventing or reducing the insoluble substances of the calcium-magnesium soap from being deposited on the hair when the shampoo is washed by hard water through the added matrix component, the moisturizing and antioxidant component and the preservative component.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential characteristics thereof. The present embodiments are, therefore, to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein.
Furthermore, it should be understood that although the present disclosure describes embodiments, not every embodiment is provided with a separate embodiment, and that this description is provided for clarity only, and that the disclosure is not limited to the embodiments described in detail below, and that the embodiments described in the examples may be combined as appropriate to form other embodiments that will be apparent to those skilled in the art.

Claims (10)

1. The head care product for preventing hair loss, fixing hair and moisturizing scalp is characterized by comprising the following raw materials in parts by weight: 5-10 parts of matrix component, 4-8 parts of liposome component, 5-15 parts of hair loss prevention and hair fixation moisturizing component, 0.5-2 parts of moisturizing and antioxidant component, 0.5-2 parts of preservative component and 100 parts of deionized water;
the liposome component is a human skin stem cell factor nanoliposome complex;
the anti-drop hair-fixing and moisturizing component comprises the following raw materials in parts by weight: 1-5 parts of cacumen biotae extract, 1-5 parts of saw palmetto extract, 1-5 parts of caffeine, 1-5 parts of red ball ginger extract, 1-5 parts of maifang pepperweed root extract and 1-5 parts of flos rosae multiflorae extract.
2. The head care product for preventing hair loss, fixing hair and moisturizing scalp according to claim 1, wherein the matrix component comprises the following raw materials in parts by weight: 1-3 parts of lanolin, 0.05-0.1 part of EDTA-2Na, 0.2-2 parts of magnesium stearate, 0.2-0.6 part of pentasodium tripolyphosphate, 0.2-0.6 part of hydroxyethyl cellulose and 0.1-0.5 part of citric acid fatty glyceride.
3. The head care product for preventing hair loss, fixing hair and moisturizing scalp according to claim 1, wherein the moisturizing and antioxidant component comprises the following raw materials in parts by weight: 1-5 parts of hydrolyzed zein, 1-3 parts of PCA zinc, 0.5-2 parts of cystine, 0.5-2 parts of cysteine and 0.1-1 part of xylitol.
4. The head care product for preventing hair loss, fixing hair and moisturizing scalp according to claim 1, wherein the preservative component comprises the following raw materials in parts by weight: 0.05-0.1 part of piroctone olamine, 0.05-0.2 part of p-hydroxyacetophenone and 0.05-0.3 part of biotin.
5. The hair care product for preventing hair loss, fixing hair and moisturizing scalp according to claim 1, further comprising 0.1-0.5 parts of essence component.
6. The hair care product for preventing hair loss, fixing hair and moisturizing scalp according to claim 5 wherein the essence component is a mixture of one or two of lavender oil and apple ester.
7. The use of a hair care product for preventing hair loss, fixing hair and moisturizing scalp as claimed in any one of claims 1 to 6 in cosmetics, wherein the hair care product is scalp essence, scalp massage cream, shampoo, hair mask and hair conditioner.
8. A method of preparing a hair care product according to any one of claims 1 to 7, comprising the steps of:
weighing the matrix component, the liposome component, the anti-hair loss and hair fixing moisturizing component, the moisturizing and antioxidant component, the preservative component and deionized water;
adding deionized water and matrix components into a reaction kettle, heating and stirring to completely dissolve solid phase matters of the matrix components, continuously stirring at constant temperature for 20-30min, slowly cooling and standing to obtain a mixture A;
step three, adding the anti-drop hair-fixing moisturizing component and the moisturizing and antioxidant component into the mixture A while stirring when the temperature of the mixture A is reduced to 40-50 ℃, stirring at constant temperature for 20-30min, uniformly dispersing, and cooling to obtain a mixture B;
sequentially adding a liposome component, a preservative component and an essence component into the mixture B prepared in the step three, and stirring at constant temperature by ultrasonic until the components are uniformly dispersed to obtain inclusion solution;
and fifthly, adding deionized water into the inclusion solution to fill up to 100 parts, uniformly stirring, standing for 10-20min, filtering and discharging to obtain the head care product for preventing hair loss, fixing hair and moistening scalp.
9. The method for preparing the hair care product for preventing hair loss, fixing hair and moisturizing scalp according to claim 8, wherein the heating and stirring method in the second step is to heat to 75-85 ℃ at 5-10 ℃/min, mechanically stir at 50-100r/min, and slowly cool at 3-5 ℃/min.
10. The method for preparing the hair care product for preventing hair loss, fixing hair and moisturizing scalp according to claim 8, wherein the cooling temperature of the mixture B in the third step is reduced to 32-38 ℃, the ultrasonic frequency in the fourth step is 25000-30000Hz, and the ultrasonic time is 10-20min.
CN202310287450.2A 2023-03-23 2023-03-23 Head care product for preventing hair loss, fixing hair and moisturizing scalp and preparation method thereof Pending CN116251052A (en)

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