CN116249778A - 编码氨基酸序列、编码氧化还原酶的多核苷酸 - Google Patents

编码氨基酸序列、编码氧化还原酶的多核苷酸 Download PDF

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Publication number
CN116249778A
CN116249778A CN202180060850.9A CN202180060850A CN116249778A CN 116249778 A CN116249778 A CN 116249778A CN 202180060850 A CN202180060850 A CN 202180060850A CN 116249778 A CN116249778 A CN 116249778A
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Chinese (zh)
Inventor
S·沙费尔
T·布拉德特
S·奥斯瓦尔特
R·玛萨
B·R·斯文森
D·T·洛根
R·潘查伊坦
M·恩格福冲
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Evonik Operations GmbH
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Evonik Operations GmbH
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Publication of CN116249778A publication Critical patent/CN116249778A/zh
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/225—Tyrosine; 3,4-Dihydroxyphenylalanine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/14—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen (1.14.14)
    • C12Y114/14009—4-Hydroxyphenylacetate 3-monooxygenase (1.14.14.9)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
CN202180060850.9A 2020-07-15 2021-07-14 编码氨基酸序列、编码氧化还原酶的多核苷酸 Pending CN116249778A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20185930.3 2020-07-15
EP20185930 2020-07-15
PCT/EP2021/069597 WO2022013287A1 (en) 2020-07-15 2021-07-14 Polynucleotide encoding an amino acid sequence, encoding an oxidoreductase

Publications (1)

Publication Number Publication Date
CN116249778A true CN116249778A (zh) 2023-06-09

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CN202180060850.9A Pending CN116249778A (zh) 2020-07-15 2021-07-14 编码氨基酸序列、编码氧化还原酶的多核苷酸

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Country Link
US (1) US20230340428A1 (https=)
EP (1) EP4182450A1 (https=)
JP (1) JP2023534790A (https=)
CN (1) CN116249778A (https=)
WO (1) WO2022013287A1 (https=)

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5976843A (en) 1992-04-22 1999-11-02 Ajinomoto Co., Inc. Bacterial strain of Escherichia coli BKIIM B-3996 as the producer of L-threonine
JP3023615B2 (ja) 1990-08-30 2000-03-21 協和醗酵工業株式会社 発酵法によるｌ―トリプトファンの製造法
DE4130867A1 (de) 1991-09-17 1993-03-18 Degussa Verfahren zur fermentativen herstellung von aminosaeuren
KR100420743B1 (ko) 1994-12-09 2004-05-24 아지노모토 가부시키가이샤 신규한리신데카복실라제유전자및l-리신의제조방법
GB2304718B (en) 1995-09-05 2000-01-19 Degussa The production of tryptophan by the bacterium escherichia coli
US5990350A (en) 1997-12-16 1999-11-23 Archer Midland Company Process for making granular L-lysine
DE102004043748A1 (de) 2004-09-10 2006-03-16 Degussa Ag Biokatalysator zur Hydrolyse von Cyanid
WO2007012078A1 (en) 2005-07-18 2007-01-25 Basf Ag Methionine producing recombinant microorganisms
US7700328B2 (en) 2006-06-07 2010-04-20 E.I. Du Pont De Nemours And Company Method for producing an L-tyrosine over-producing bacterial strain
WO2009043372A1 (en) 2007-10-02 2009-04-09 Metabolic Explorer Increasing methionine yield
WO2010080408A2 (en) * 2008-12-19 2010-07-15 Novozymes, Inc. Methods for increasing enzymatic hydrolysis of cellulosic material in the presence of a peroxidase
AU2010291208B2 (en) * 2009-09-02 2015-04-09 Purac Biochem B.V. Polypeptides having oxidoreductase activity and their uses
PL2655612T3 (pl) * 2010-12-23 2017-12-29 Shell Internationale Research Maatschappij B.V. Czynniki uszkadzające geny produkujące pochodne tłuszczowego acylo-coa
EP3150712B1 (en) 2015-10-02 2021-12-01 Symrise AG Biotechnological methods for providing 3,4-dihydroxyphenyl compounds and methylated variants thereof
CN107541483B (zh) 2017-10-24 2020-12-01 中国科学院天津工业生物技术研究所 生产左旋多巴大肠杆菌重组菌株及其构建方法与应用
CN120699921A (zh) * 2025-06-09 2025-09-26 江南大学 一种氧化还原酶突变体及其应用

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JP2023534790A (ja) 2023-08-14
EP4182450A1 (en) 2023-05-24
WO2022013287A1 (en) 2022-01-20
US20230340428A1 (en) 2023-10-26

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