CN1162464A - Microorgan and Chinese medical herb composition and the preparation method - Google Patents
Microorgan and Chinese medical herb composition and the preparation method Download PDFInfo
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- CN1162464A CN1162464A CN96115220A CN96115220A CN1162464A CN 1162464 A CN1162464 A CN 1162464A CN 96115220 A CN96115220 A CN 96115220A CN 96115220 A CN96115220 A CN 96115220A CN 1162464 A CN1162464 A CN 1162464A
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- enterococcus faecalis
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Abstract
A compound preparation of microbe and Chinese-medicinal materials for quickly increasing human immunity and patching organism features that the microbe preparation includes streptococcus fecalis and its fermented metabolin liquid and is prepared through mixing to culture liquid, sterilizing, adding leavening agent, fermenting and filtering. The Chinese-medicinal one is prepared through water extraction. The compound is obtained through mixing them, sterilizing and examinating.
Description
The present invention relates to C12N 1/20 class, antibacterial and culture medium thereof and BO1D 12/00 class, the liquid displacement separation method, the compound formulation of a kind of microorganism and Chinese herbal and crude drugs preparations and preparation method are used as medicine and health promoting beverage, food additive.
The zymogenic utilization of microbial bacterial is with a long history at grocery trade, but utilizes one mainly to be limited to field of medicaments over 100 years to microbial bacterial always.In recent years, the health product between food and medicine have benefited from method for cultivation of bacteria, are very much flourishing.For example SANZHU KOUFUYE, bismuth potassium citrate all are to adopt bacterial fermentation processes, and similar biological product are a lot.The advantage of this based article is to control bacterium with bacterium, is fit to the interior ecological environment of human body, and the adjustable body ecological balance of giving sb. a hard time improves body immunity, health invigorating, can also with the food compatibility, instant does not have the effect of paying.Weak point is that the viable bacteria of this based article is short life cycle, is an impediment to the large-area applications exploitation.Consider that from the long-range application point that ensures people ' s health this bacterioid and the traditional tonic compatibility in the Chinese herbal medicine with had easily and effectively both had to eat the nourishing curative effect for medicine, can to body mending function be arranged as the bonded new medicament of Chinese medicine again.
The purpose of this invention is to provide a kind of microbial bacterial and Chinese herbal medicine complexing agent and preparation method thereof, Chinese medicine and western medicine is combined into one, comprise health product and medicine, expand its application.
The microbial bacterial preparation of this complexing agent is the fermentating metabolism liquid after peptone, glucose, meat extract, water etc. are prepared with strain, and antibacterial is enterococcus faecalis (Enterococcus faecalis); Chinese herbal and crude drugs preparations is that the proportioning that it is characterized in that microorganism formulation and extracts of Chinese herbal medicine is 2: 1 according to the extracts of Chinese herbal medicine of the compatibility of medicines in a prescription commonly used.The preparation method of this complexing agent comprises produces two kinds of preparations respectively: the material component of microbiological culture media is mixed by proportioning, makes culture fluid through sterilization, add leaven, fermentation, filter bacteria preparation; To be soaked in water by the Chinese herbal medicine that component prepares, heat decoction, extract, filter, make Chinese medicine preparation, two kinds of preparations are mixed,, get finished product through sterilization, inspection process.
The preparation technology of this invention combines current microbial technique with traditional Chinese herbal medicine, concentrate the Chinese herbal medicine of microorganism multiple nutrients material and auxiliary tonic Chinese medicine or treatment, with human body the biological preparation of easy absorption be carrier, consolidate with Chinese medicine and to set upright, can strengthen body immunity rapidly and body is played the repairing effect.Especially gastral various inflammation there is mending function, can resists the invasion of adventitious viruses, suppress the growth of harmful bacterium in the body.This preparation method only contains metabolite and the medium-height grass the effective elements of the medicine of antibacterial through two-stage sterilization in microniological proudcts, do not contain viable bacteria, is convenient to preserve. is through the check of food hygiene department, and it is as follows that the microorganism formulation in this complexing agent contains various aminoacid ingredients: title NAME content mg/Kg title NAME content mg/Kg aspartic acid ASP 458.85 isoleucine ILE 231.70 threonine THR 169.39 leucine LEU 327.58 serine SER 218.74 tyrosine TYR 203.93 glutamic acid GLU 965.97 phenylalanine PHE 240.61 proline PRO 322.18 lysine LYS 310.39 glycine GLY 234.12 histidine HIS 117.81 alanine ALA 235.09 ammonia NH3 26.47 cystine CYS 17.17 arginine ARG 291.17 valine VAL 244.38 tryptophan TRP 12.51 methionine MET 77.62 microorganism formulations contain various active ingredients: (%)
Protein 2.29
Fat 0.27 total sugar 0.48
Vitamin A (IV/100ml) 19.13 selenium (in Se, mg/l) 0.002
Vitamin C (mg/100ml) 9.2 zinc (in Zn, mg/l) 2.6
Vitamin E (mg/100ml) 0.1 ferrum (in Fe, mg/l) 7.3
Calcium (in Ca, mg/l) 70.1
Embodiment:
The component of compound formulation of the present invention comprises microbial bacterial fermentating metabolism liquid and Chinese herbal and crude drugs preparations, and the microbial bacterial media components by weight percentage; Peptone 2%, glucose 0.2%, sodium chloride 0.5%, meat extract 0.3%, L-cysteine 0.1%, sodium hydrogen phosphate 0.25%, all the other 96.65% are water; With the culture fluid sterilization, 115 ℃-120 ℃, 1atm, three grade fermemtation is carried out in inoculation then; With the proportioning of strain be 1: 0.01 enterococcus faecalis (Enterococcus faecalis).The Chinese herbal and crude drugs preparations component: Radix Glycyrrhizae 10g, Rhizoma Zingiberis Recens 10g, Pericarpium Citri Reticulatae 15g, Fructus Hordei Germinatus 20g, Fructus Jujubae 15g, Os Sepiae 5g adds the water of above-mentioned component summation treble amount.Chinese medicine preparation can be according to the product requirement assembly, for example, can adopt at diabetes patient's Chinese medicine preparation: Fructus Lycii, Rhizoma Dioscoreae, each 30g of Radix Trichosanthis; Herb Gynostemmae Pentaphylli, each 20g of Flos Chrysanthemi Indici; Fry garden Fructus Tribuli 20g, Rhizoma Coptidis 10g, water 600g, Chinese medicine preparation and microbial bacterial preparation are pressed 1: 2 compatibility, and be all good to I, type ii diabetes effect.Can adopt at patients with coronary heart disease: Folium Ginkgo, Folium Kaki, Spica Prunellae, Herb Gynostemmae Pentaphylli, each 30g of Fructus Lycii, Flos Carthami, Flos Chrysanthemi Indici, each 20g of Semen Ziziphi Spinosae, Fructus Crataegi 50g, Radix Salviae Miltiorrhizae 10g, water 800g, press 1: 2 compatibility with the microbial bacterial preparation.Effect: blood pressure lowering, blood fat reducing, splendid to treatment with prevention coronary heart disease effect.
The preparation technology of this invention is as follows: need to be equipped with microbial fermentation equipment, Chinese herbal medicine extracting equipment, high-pressure boiler, autoclaving equipment, fill, detection, washing, sanitary ware; Produce two kinds of preparations respectively, it is characterized in that the microorganism formulation material component is mixed and made into culture fluid by said ratio, detecting pH value is 7, carries out sterilization treatment, and temperature 115-120 ℃, pressure 1atm was in 0.01: 1 ratio; Bacteria leaven enterococcus faecalis (Enterococcus faecalis) is added in the above-mentioned raw materials culture fluid, carry out third level fermentation, keep fermentation temperature about 35-37 ℃, 36 hours time, flora index reached 106-108/, adopt high-pressure filteration, carry out routine operation by flow, pressure that fermentation tank disposed and get the microbial bacterial preparation; Chinese herbal medicine is added triple water logging bubble by the prescription proportioning, the decoction of heating, 80-100 ℃, 30-50 minute, filter, get extracts of Chinese herbal medicine.Two kinds of preparations are pressed microorganism formulation and 2: 1 mixed of Chinese herbal and crude drugs preparations,, 20-30 minute, carry out product quality and detect, bottling sampling observation, finished product warehouse-in through sterilization 80-115 ℃, 1atm.
Claims (2)
1, a kind of microbial bacterial and Chinese herbal medicine complexing agent and preparation method, complexing agent comprises microorganism fermenting metabolizing liquor and Chinese herbal and crude drugs preparations, it is characterized in that the microbial bacterial media components by weight percentage; Peptone 2%, glucose 0.2%, sodium chloride 0.5%, meat extract 0.3%, L-cysteine 0.1%, sodium hydrogen phosphate 0.25%, all the other 96.65% are water; The proportioning of culture medium fermentation liquid and strain is 1: 0.01 enterococcus faecalis (Enterococcus faecalis); The Chinese herbal and crude drugs preparations component: Radix Glycyrrhizae 10g, Rhizoma Zingiberis Recens 10g, Pericarpium Citri Reticulatae 15g, Fructus Hordei Germinatus 20g, Fructus Jujubae 15g, Os Sepiae 5g adds the water of above-mentioned component summation treble amount; The proportioning of microorganism formulation and Chinese medicine preparation is 2: 1.
2, a kind of preparation method of complexing agent as claimed in claim 1, process two kinds of preparations respectively, it is characterized in that the microorganism formulation material component is mixed and made into culture fluid by said ratio, detecting pH value is 7, carry out sterilization treatment, temperature 115-120 ℃, pressure 1atm, add bacteria leaven enterococcus faecalis (Enterococcus faecalis) in 1: 0.01 ratio, carry out third level fermentation, keep fermentation temperature at 35-37 ℃, 36 hours time, flora index 106-108/, adopt high-pressure filteration, by the flow that fermentation tank disposed, pressure carries out routine operation and gets the microbial bacterial preparation; Chinese herbal medicine is added triple water logging bubble by proportioning, the decoction of heating, 80-100 ℃, 30-50 minute, filter, get herbal mediciment; In 2: 1 ratios microorganism formulation is mixed with Chinese herbal and crude drugs preparations,, 20-30 minute, carry out product quality and detect, bottling sampling observation, finished product warehouse-in through sterilization 80-115 ℃, 1atm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96115220A CN1162464A (en) | 1996-04-12 | 1996-04-12 | Microorgan and Chinese medical herb composition and the preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96115220A CN1162464A (en) | 1996-04-12 | 1996-04-12 | Microorgan and Chinese medical herb composition and the preparation method |
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| CN1162464A true CN1162464A (en) | 1997-10-22 |
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| CN96115220A Pending CN1162464A (en) | 1996-04-12 | 1996-04-12 | Microorgan and Chinese medical herb composition and the preparation method |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101037662B (en) * | 2007-02-14 | 2011-06-22 | 中国人民解放军第三军医大学第一附属医院 | Complex culture medium for lactobacillus ferment and preparation method thereof |
| CN103404709A (en) * | 2013-08-29 | 2013-11-27 | 三门峡为宝生物科技有限公司 | Feed additive produced from waste liquid and dregs in pharmaceutical factory and preparation method of feed additive |
| CN105709151A (en) * | 2016-03-10 | 2016-06-29 | 深圳市水圣堂生物工程股份有限公司 | Natural traditional Chinese medicine preparation for regulating five internal organs, reinforcing life-gate, dredging heart and brain, nourishing yin and reinforcing kidney and preparation method thereof |
-
1996
- 1996-04-12 CN CN96115220A patent/CN1162464A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101037662B (en) * | 2007-02-14 | 2011-06-22 | 中国人民解放军第三军医大学第一附属医院 | Complex culture medium for lactobacillus ferment and preparation method thereof |
| CN103404709A (en) * | 2013-08-29 | 2013-11-27 | 三门峡为宝生物科技有限公司 | Feed additive produced from waste liquid and dregs in pharmaceutical factory and preparation method of feed additive |
| CN103404709B (en) * | 2013-08-29 | 2014-11-05 | 三门峡为宝生物科技有限公司 | Feed additive produced from waste liquid and dregs in pharmaceutical factory and preparation method of feed additive |
| CN105709151A (en) * | 2016-03-10 | 2016-06-29 | 深圳市水圣堂生物工程股份有限公司 | Natural traditional Chinese medicine preparation for regulating five internal organs, reinforcing life-gate, dredging heart and brain, nourishing yin and reinforcing kidney and preparation method thereof |
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