CN116210898A - Compound fungal polysaccharide product for regulating glycolipid metabolism through immune activation - Google Patents

Compound fungal polysaccharide product for regulating glycolipid metabolism through immune activation Download PDF

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Publication number
CN116210898A
CN116210898A CN202310391367.XA CN202310391367A CN116210898A CN 116210898 A CN116210898 A CN 116210898A CN 202310391367 A CN202310391367 A CN 202310391367A CN 116210898 A CN116210898 A CN 116210898A
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powder
parts
fungus
polysaccharide product
morchella
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陈增华
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Beijing Qianjunfang Mycological Research Institute
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Beijing Qianjunfang Mycological Research Institute
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L31/00Edible extracts or preparations of fungi; Preparation or treatment thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23PSHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00Shaping or working of foodstuffs characterised by the products
    • A23P10/20Agglomerating; Granulating; Tabletting
    • A23P10/28Tabletting; Making food bars by compression of a dry powdered mixture
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Microbiology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The invention discloses a compound fungus polysaccharide product for regulating glycolipid metabolism through immune activation, which comprises the following components in parts by weight: 5-15 parts of hericium erinaceus powder, 5-15 parts of poria cocos powder, 5-15 parts of bamboo fungus powder, 5-15 parts of agaricus blazei murill powder, 3-10 parts of cordyceps militaris powder, 3-10 parts of ash tree pollen, 3-10 parts of white ginseng fungus powder, 3-10 parts of tremella aurantifolia powder, 3-8 parts of morchella powder, 3-8 parts of russula powder, 3-8 parts of black truffle powder and 3-8 parts of pine mushroom powder; according to the invention, the compound fungus polysaccharide product for regulating glycolipid metabolism through immune activation is prepared from hericium erinaceus powder, poria cocos powder, bamboo fungus powder, agaricus blazei murill powder, cordyceps militaris powder, ash tree pollen, white ginseng fungus powder, pleurotus ostreatus powder, morchella powder, russula powder, black truffle powder and tricholoma matsutake powder, so that the immune activity can be stimulated, the glycolipid metabolism can be regulated, lymphocyte transformation is promoted, T cells and B cells are activated, and the formation of antibodies is promoted, so that the antitumor effect is realized.

Description

Compound fungal polysaccharide product for regulating glycolipid metabolism through immune activation
Technical Field
The invention relates to the technical field of health products, in particular to a compound fungus polysaccharide product for regulating glycolipid metabolism through immune activation.
Background
The fungus polysaccharide has extremely strong repairing effect on cells. The fungus polysaccharide health food can timely supplement substances such as polysaccharide lacking in the interstitial space of cells, so that damaged cells can be timely repaired, and the purposes of keeping cell health, prolonging cell life and realizing human health are achieved. Experiments of Shanghai medical university Li Rui and the like show that the fungus polysaccharide can obviously improve the fluidity and the sealing degree of cell membranes, the sealing degree is improved by 11 percent, the fluidity is improved by 32 percent, and the cell membrane fluidity and the sealing property are improved after the aged cells are cultured by the fungus polysaccharide, which indicates that the physiological functions of the cells are improved.
The fungal polysaccharide also has hypolipidemic properties: reducing the content of cholesterol and triglyceride, reducing the deposition of lipid on the wall of a blood vessel, inhibiting platelet aggregation and reducing the viscosity of blood, but the current commercial fungal polysaccharide products have unsatisfactory effects of regulating the metabolism of glycolipid;
the invention provides a compound fungus polysaccharide product for regulating glycolipid metabolism through immune activation, which has the health care effect of regulating glycolipid metabolism and solves the problem of unsatisfactory effect of the current health care products.
Disclosure of Invention
The present invention aims to provide a complex fungal polysaccharide product for regulating glycolipid metabolism by immune activation, which solves the problems set forth in the background art.
In order to achieve the above purpose, the present invention provides the following technical solutions: a compound fungus polysaccharide product for regulating glycolipid metabolism through immune activation comprises the following components in parts by weight: 5-15 parts of hericium erinaceus powder, 5-15 parts of poria cocos powder, 5-15 parts of bamboo fungus powder, 5-15 parts of agaricus blazei murill powder, 3-10 parts of cordyceps militaris powder, 3-10 parts of ash tree pollen, 3-10 parts of white ginseng fungus powder, 3-10 parts of golden top side fungus powder, 3-8 parts of morchella powder, 3-8 parts of russula powder, 3-8 parts of black truffle powder and 3-8 parts of pine mushroom powder.
Wherein the composition comprises the following components in parts by weight: 10 parts of hericium erinaceus powder, 10 parts of poria cocos powder, 10 parts of bamboo fungus powder, 10 parts of agaricus blazei murill powder, 3 parts of cordyceps militaris powder, 3 parts of ash tree pollen, 3 parts of white ginseng fungus powder, 3 parts of tremella aurantialba powder, 5 parts of morchella powder, 5 parts of russula powder, 5 parts of black truffle powder and 5 parts of pine mushroom powder.
Wherein the composition comprises the following components in parts by weight: 10 parts of hericium erinaceus powder, 10 parts of poria cocos powder, 10 parts of bamboo fungus powder, 10 parts of agaricus blazei murill powder, 6 parts of cordyceps militaris powder, 6 parts of ash tree pollen, 6 parts of white ginseng fungus powder, 6 parts of tremella aurantialba powder, 5 parts of morchella powder, 5 parts of russula powder, 5 parts of black truffle powder and 5 parts of pine mushroom powder.
Wherein the composition comprises the following components in parts by weight: 10 parts of hericium erinaceus powder, 10 parts of poria cocos powder, 10 parts of bamboo fungus powder, 10 parts of agaricus blazei murill powder, 10 parts of cordyceps militaris powder, 10 parts of ash tree pollen, 10 parts of white ginseng fungus powder, 10 parts of tremella aurantialba powder, 5 parts of morchella powder, 5 parts of russula powder, 5 parts of black truffle powder and 5 parts of pine mushroom powder.
Wherein, a compound fungus polysaccharide product for regulating glycolipid metabolism by immune activation, the preparation method of the product comprises the following steps:
s1, respectively weighing hericium erinaceus powder, poria cocos powder, bamboo fungus powder, agaricus blazei murill powder, cordyceps militaris powder, ash tree pollen, white ginseng fungus powder, oyster mushroom powder, morchella powder, russula powder, black truffle powder and tricholoma matsutake powder according to parts by weight for later use;
s2, sieving with a 60-120 mesh sieve, and uniformly mixing to obtain a mixed raw material;
s3, tabletting the mixed raw materials through a tablet press to obtain a composite fungus polysaccharide product for regulating glycolipid metabolism through immune activation.
The hericium erinaceus powder contains a large amount of unsaturated fatty acid, can effectively reduce cholesterol in blood, and has good effects of treating hypertension and hyperlipidemia; oligosaccharide contained in Hericium erinaceus powder can be used for treating chronic atrophic gastritis; hericium erinaceus powder contains a large amount of polypeptides, and can prevent cancer.
Poria powder has effect in promoting urination, and has sweet taste, and can promote urination and resist bacteria, and is mainly used for treating symptoms such as body edema, frequent urination, obstruction of urethra, dizziness, palpitation and short breath caused by cold, heat, deficiency and excess constitution. Also has tranquillizing effect, and Poria has effects of invigorating heart and spleen, invigorating spleen, promoting qi and blood circulation, and tranquilizing mind. Can be used for treating heart and spleen deficiency caused by restlessness of heart and mind, or palpitation and insomnia. In addition, the poria cocos powder has the effects of strengthening spleen and nourishing stomach, tonifying spleen and middle-jiao, excreting dampness and stopping diarrhea and the like, and has certain effects on anorexia, tiredness, diarrhea and loose stool caused by spleen deficiency and excessive dampness.
The Dictyophora Indusiata powder has effects of invigorating qi and spleen, promoting salivation, quenching thirst, and tranquilizing mind. It can be used for treating listlessness, limb debilitation, loose stool, cough, debilitation, spontaneous perspiration, and palpitation, insomnia, dizziness, dry mouth, dry throat, tinnitus, constipation, etc. due to deficiency of both qi and blood or deficiency of both qi and yin.
The agaricus blazei murill powder can enhance the immune function of a human body, enhance the autoimmune function of the human body through enhancing the function of a mononuclear macrophage system, inhibit cell division and regulate immune system reaction, thereby resisting and interfering virus growth; can promote hematopoietic function of human bone marrow, inhibit bone marrow hematopoietic function by improving chemotherapy to make peripheral hemoglobin concentration, total number of platelet white cells, and trend to normal value, and inhibit tumor cells, and can strengthen body constitution and improve health after long-term administration; has anticancer and antitumor effects, and contains polysaccharides and steroids as main ingredients, and can directly promote immunocyte activity, inhibit tumor cell growth, and have remarkable inhibiting effect on various tumor cells.
The Cordyceps militaris powder can help the body of a person to trend to a normal direction to help the body to improve immunity, has good curative effect on treating chronic trachitis and pneumonia, can eliminate bacteria, remove radicals, reduce blood pressure and blood sugar, and has good health care effect.
The ash tree pollen mainly has the functions of replenishing qi to invigorate the spleen, tonifying deficiency and strengthening the body resistance, so that the ash tree pollen is mainly used for treating spleen deficiency and qi weakness, tiredness and hypodynamia, listlessness and lazy speaking, diet reduction and abdominal distension after eating, and can be applied to some tumor patients for radiotherapy or chemotherapy.
The white ginseng fungus powder has the effects of promoting the production of body fluid, nourishing yin, clearing deficiency heat, tonifying qi and strengthening body, and particularly has good effects on cough caused by semen deficiency and lung dryness. Can also be used for treating thirst, and has good relieving effect on constipation caused by dry stool.
The Pleurotus cornucopiae powder contains multiple nutritional components such as protein, vitamins and minerals, wherein the content of amino acids is especially rich, the content of essential amino acids is high, and the Pleurotus cornucopiae powder belongs to a high-nutrition and low-calorie food, has the functions of reducing blood pressure and cholesterol content after long-term eating, and is an ideal health food for old people suffering from cardiovascular diseases and obesity. Can be used as medicine for treating weak wilt (myopathy) and dysentery. Has tonic effect.
Morchella esculenta powder has a certain effect of improving the immunity of organisms, because Morchella esculenta is rich in a certain amount of mucilaginous polysaccharides, and the mucilaginous polysaccharides can play a positive role in promoting the generation of immune substances. Therefore, if the Morchella esculenta is properly eaten to supplement mucopolysaccharide, the production of immune substances is promoted, and the Morchella esculenta has positive effects on improving the immunity of organisms, so that the Morchella esculenta can play a role in reducing the incidence rate of infectious diseases.
The russula powder contains various amino acids essential to human beings. Has therapeutic effects on tumor, especially lung tumor, soreness of waist and legs, numbness of limbs, discomfort of tendons and bones, convulsion of limbs, blood tonifying, yin nourishing, refreshing and detoxicating, anemia, edema, malnutrition, and puerperal hemorrhage.
The black truffle powder contains abundant proteins, 18 amino acids, unsaturated fatty acids, multiple vitamins, microelements, mineral matters and the like, has extremely high nutritional and health care values, has the effects of supporting yang, regulating endocrine, enhancing immunity, resisting aging and fatigue, and has the effects of nourishing yin, regulating menstruation and maintaining beauty and keeping young for females.
The Tricholoma matsutake powder contains abundant vitamins, vitamin B1, vitamin B2, and vitamin C, and contains many crude proteins, pure proteins, and crude fat with anticancer effects. The Tricholoma matsutake has effects of strengthening body constitution, regulating stomach and intestine, and can be used for treating diabetes and resisting cancer.
Compared with the prior art, the invention has the beneficial effects that:
according to the invention, the compound fungus polysaccharide product for regulating glycolipid metabolism through immune activation is prepared from hericium erinaceus powder, poria cocos powder, bamboo fungus powder, agaricus blazei murill powder, cordyceps militaris powder, ash tree pollen, white ginseng fungus powder, pleurotus ostreatus powder, morchella powder, russula powder, black truffle powder and tricholoma matsutake powder, so that the immune activity can be stimulated, the glycolipid metabolism can be regulated, lymphocyte transformation is promoted, T cells and B cells are activated, and the formation of antibodies is promoted, so that the antitumor effect is realized.
Detailed Description
The following description of the technical solutions in the embodiments of the present invention will be clear and complete, and it is obvious that the described embodiments are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Example 1
A compound fungus polysaccharide product for regulating glycolipid metabolism through immune activation comprises the following components in parts by weight: 10 parts of hericium erinaceus powder, 10 parts of poria cocos powder, 10 parts of bamboo fungus powder, 10 parts of agaricus blazei murill powder, 3 parts of cordyceps militaris powder, 3 parts of ash tree pollen, 3 parts of white ginseng fungus powder, 3 parts of tremella aurantialba powder, 5 parts of morchella powder, 5 parts of russula powder, 5 parts of black truffle powder and 5 parts of pine mushroom powder.
A complex fungal polysaccharide product for regulating glycolipid metabolism by immune activation, the method of preparation comprising the steps of:
s1, respectively weighing hericium erinaceus powder, poria cocos powder, bamboo fungus powder, agaricus blazei murill powder, cordyceps militaris powder, ash tree pollen, white ginseng fungus powder, oyster mushroom powder, morchella powder, russula powder, black truffle powder and tricholoma matsutake powder according to parts by weight for later use;
s2, sieving with a 60-120 mesh sieve, and uniformly mixing to obtain a mixed raw material;
s3, tabletting the mixed raw materials through a tablet press to obtain a composite fungus polysaccharide product for regulating glycolipid metabolism through immune activation.
Example 2
A compound fungus polysaccharide product for regulating glycolipid metabolism through immune activation comprises the following components in parts by weight: 10 parts of hericium erinaceus powder, 10 parts of poria cocos powder, 10 parts of bamboo fungus powder, 10 parts of agaricus blazei murill powder, 6 parts of cordyceps militaris powder, 6 parts of ash tree pollen, 6 parts of white ginseng fungus powder, 6 parts of tremella aurantialba powder, 5 parts of morchella powder, 5 parts of russula powder, 5 parts of black truffle powder and 5 parts of pine mushroom powder.
The preparation method was the same as that of example 1, except that the parts by weight of the respective components were different.
Example 3
A compound fungus polysaccharide product for regulating glycolipid metabolism through immune activation comprises the following components in parts by weight: 10 parts of hericium erinaceus powder, 10 parts of poria cocos powder, 10 parts of bamboo fungus powder, 10 parts of agaricus blazei murill powder, 10 parts of cordyceps militaris powder, 10 parts of ash tree pollen, 10 parts of white ginseng fungus powder, 10 parts of tremella aurantialba powder, 5 parts of morchella powder, 5 parts of russula powder, 5 parts of black truffle powder and 5 parts of pine mushroom powder.
The preparation method was the same as that of example 1, except that the parts by weight of the respective components were different.
Experimental example
Mice were used for experiments, males, weighing 30-40g, were randomly divided into groups A, B, C, and D (four groups), 10 each, and fed conventionally.
Mice in group A were fed 5g of the product prepared in example 1 each day; group B mice were fed 5g of the product prepared in example 2 each day; mice in group C were fed 5g of the product prepared in example 3 each day; group D mice were fed 5g of normal saline each day for 60 days (during feeding the products prepared in examples 1-3 and normal saline, the mice were fed with the feed at regular intervals each day, ensuring their normal feeding needs).
The mice were observed for body weight, mental status, fecal morphology, and mortality, and the results are shown in the following table.
Figure BDA0004175887650000061
As can be seen from the table, after the products prepared in examples 1-3 are fed, the weight of the mice is obviously increased, the mental state is good, the excrement is not abnormal, after 60 days of feeding, the mice are not dead, after 60 days of feeding, the weight of the mice is not obviously increased, the mental state is low, the excrement is not formed, and death exists, so that the compound fungus polysaccharide product for regulating the metabolism of glycolipid through immune activation is prepared from hericium erinaceus powder, poria cocos powder, bamboo fungus powder, agaricus blazei powder, cordyceps militaris powder, ash tree pollen, white ginseng fungus powder, golden top side fungus powder, morchella powder, russian powder, black pine dew powder, and pine mushroom powder, so that the immunocompetence can be stimulated, the metabolism of glycolipid can be regulated, and the growth of the mice can be facilitated.
Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (5)

1. A compound fungus polysaccharide product for regulating glycolipid metabolism through immune activation is characterized by comprising the following components in parts by weight: 5-15 parts of hericium erinaceus powder, 5-15 parts of poria cocos powder, 5-15 parts of bamboo fungus powder, 5-15 parts of agaricus blazei murill powder, 3-10 parts of cordyceps militaris powder, 3-10 parts of ash tree pollen, 3-10 parts of white ginseng fungus powder, 3-10 parts of golden top side fungus powder, 3-8 parts of morchella powder, 3-8 parts of russula powder, 3-8 parts of black truffle powder and 3-8 parts of pine mushroom powder.
2. The complex fungal polysaccharide product according to claim 1, wherein the complex fungal polysaccharide product comprises the following components in parts by weight: 10 parts of hericium erinaceus powder, 10 parts of poria cocos powder, 10 parts of bamboo fungus powder, 10 parts of agaricus blazei murill powder, 3 parts of cordyceps militaris powder, 3 parts of ash tree pollen, 3 parts of white ginseng fungus powder, 3 parts of tremella aurantialba powder, 5 parts of morchella powder, 5 parts of russula powder, 5 parts of black truffle powder and 5 parts of pine mushroom powder.
3. The complex fungal polysaccharide product according to claim 1, wherein the complex fungal polysaccharide product comprises the following components in parts by weight: 10 parts of hericium erinaceus powder, 10 parts of poria cocos powder, 10 parts of bamboo fungus powder, 10 parts of agaricus blazei murill powder, 6 parts of cordyceps militaris powder, 6 parts of ash tree pollen, 6 parts of white ginseng fungus powder, 6 parts of tremella aurantialba powder, 5 parts of morchella powder, 5 parts of russula powder, 5 parts of black truffle powder and 5 parts of pine mushroom powder.
4. The complex fungal polysaccharide product according to claim 1, wherein the complex fungal polysaccharide product comprises the following components in parts by weight: 10 parts of hericium erinaceus powder, 10 parts of poria cocos powder, 10 parts of bamboo fungus powder, 10 parts of agaricus blazei murill powder, 10 parts of cordyceps militaris powder, 10 parts of ash tree pollen, 10 parts of white ginseng fungus powder, 10 parts of tremella aurantialba powder, 5 parts of morchella powder, 5 parts of russula powder, 5 parts of black truffle powder and 5 parts of pine mushroom powder.
5. A complex fungal polysaccharide product according to any of claims 1 to 4 for regulating glycolipid metabolism by immune activation, wherein the process for the preparation of the product comprises the steps of:
s1, respectively weighing hericium erinaceus powder, poria cocos powder, bamboo fungus powder, agaricus blazei murill powder, cordyceps militaris powder, ash tree pollen, white ginseng fungus powder, oyster mushroom powder, morchella powder, russula powder, black truffle powder and tricholoma matsutake powder according to parts by weight for later use;
s2, sieving with a 60-120 mesh sieve, and uniformly mixing to obtain a mixed raw material;
s3, tabletting the mixed raw materials through a tablet press to obtain a composite fungus polysaccharide product for regulating glycolipid metabolism through immune activation.
CN202310391367.XA 2023-04-13 2023-04-13 Compound fungal polysaccharide product for regulating glycolipid metabolism through immune activation Withdrawn CN116210898A (en)

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