CN116177114B - Nucleic acid detection equipment based on automatic sampling - Google Patents
Nucleic acid detection equipment based on automatic sampling Download PDFInfo
- Publication number
- CN116177114B CN116177114B CN202211666385.6A CN202211666385A CN116177114B CN 116177114 B CN116177114 B CN 116177114B CN 202211666385 A CN202211666385 A CN 202211666385A CN 116177114 B CN116177114 B CN 116177114B
- Authority
- CN
- China
- Prior art keywords
- fixed
- rod
- shaped
- panel
- sliding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 150000007523 nucleic acids Chemical class 0.000 title claims abstract description 30
- 102000039446 nucleic acids Human genes 0.000 title claims abstract description 30
- 108020004707 nucleic acids Proteins 0.000 title claims abstract description 30
- 238000001514 detection method Methods 0.000 title claims abstract description 27
- 238000005070 sampling Methods 0.000 title claims abstract description 26
- 238000010008 shearing Methods 0.000 claims description 21
- 238000005096 rolling process Methods 0.000 claims description 11
- 230000002457 bidirectional effect Effects 0.000 claims description 10
- 230000005540 biological transmission Effects 0.000 claims description 7
- 230000006835 compression Effects 0.000 claims description 6
- 238000007906 compression Methods 0.000 claims description 6
- 230000005570 vertical transmission Effects 0.000 claims description 3
- 238000000034 method Methods 0.000 abstract description 9
- 208000015181 infectious disease Diseases 0.000 abstract description 7
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000010586 diagram Methods 0.000 description 6
- 238000006243 chemical reaction Methods 0.000 description 5
- 210000003128 head Anatomy 0.000 description 4
- 241000700605 Viruses Species 0.000 description 3
- 230000000694 effects Effects 0.000 description 2
- 208000035473 Communicable disease Diseases 0.000 description 1
- 241000711573 Coronaviridae Species 0.000 description 1
- 206010011409 Cross infection Diseases 0.000 description 1
- 206010029803 Nosocomial infection Diseases 0.000 description 1
- 241000276425 Xiphophorus maculatus Species 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000012678 infectious agent Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000000214 mouth Anatomy 0.000 description 1
- 210000002200 mouth mucosa Anatomy 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Classifications
-
- E—FIXED CONSTRUCTIONS
- E04—BUILDING
- E04H—BUILDINGS OR LIKE STRUCTURES FOR PARTICULAR PURPOSES; SWIMMING OR SPLASH BATHS OR POOLS; MASTS; FENCING; TENTS OR CANOPIES, IN GENERAL
- E04H1/00—Buildings or groups of buildings for dwelling or office purposes; General layout, e.g. modular co-ordination or staggered storeys
- E04H1/12—Small buildings or other erections for limited occupation, erected in the open air or arranged in buildings, e.g. kiosks, waiting shelters for bus stops or for filling stations, roofs for railway platforms, watchmen's huts or dressing cubicles
- E04H1/1205—Small buildings erected in the open air
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
- A61B10/0051—Devices for taking samples of body liquids for taking saliva or sputum samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
- B65G29/00—Rotary conveyors, e.g. rotating discs, arms, star-wheels or cones
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
- B65G47/00—Article or material-handling devices associated with conveyors; Methods employing such devices
- B65G47/74—Feeding, transfer, or discharging devices of particular kinds or types
- B65G47/90—Devices for picking-up and depositing articles or materials
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
- C12M33/02—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by impregnation, e.g. using swabs or loops
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Architecture (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Organic Chemistry (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Sustainable Development (AREA)
- Pulmonology (AREA)
- Civil Engineering (AREA)
- Structural Engineering (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Mechanical Engineering (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention belongs to the technical field of nucleic acid collection, in particular to automatic sampling-based nucleic acid detection equipment, which aims at the problem that in the prior art, medical staff is required to be in contact with a person to be collected to increase infection risk. According to the invention, each used collection rod can be placed in sequence, and a plurality of working procedures exist between the medical staff and the collection tube for containing the collection rod, so that possible infection of the medical staff and the detected staff can be effectively avoided, and the device is applicable to collection of disease samples with higher infectivity.
Description
Technical Field
The invention relates to the technical field of nucleic acid collection, in particular to a nucleic acid detection device based on automatic sampling.
Background
The current nucleic acid and virus detection sampling suffers from the following disadvantages: the lack of unmanned operation completes the nucleic acid detection sampling executable scheme, thereby allowing medical staff and potential virus infectious agents to directly contact, increasing the possibility and labor intensity of the medical staff being infected, and being unable to effectively protect the related medical staff, especially the occasion of virus detection throat sampling of high infectious diseases such as new coronavirus, at present, an unmanned intelligent nucleic acid detection throat sampling device is needed. According to the search, in the prior art with the publication number of CN114480102A, a nucleic acid detection device and a nucleic acid detection method are provided, wherein the nucleic acid detection device comprises a shell part and a reaction part, the shell part is provided with a sample cavity, a first observation cavity and a second observation cavity, and the reaction part is provided with a first reaction cavity and a second reaction cavity; the sample cavity is communicated with the first reaction cavity; although the device is provided with a series of devices for detecting the sample, the device does not solve the problem that the collected sample is in contact with the collected sample, so that the risk of infection of the collected personnel still exists during the sampling; there is therefore a need for a novel nucleic acid detection device that can isolate the collector from the collector.
Disclosure of Invention
The invention provides automatic sampling-based nucleic acid detection equipment, which comprises a box shell with a cuboid structure as a whole, wherein a vertical panel is reserved on the front surface of the box shell, two sides of the panel are respectively fixed with side guard plates which are parallel to each other, a horizontally arranged mounting plate is fixed in the middle of the back surface of the panel, a rotating disc is rotationally connected on the mounting plate, the end part of the rotating disc penetrates through the panel to the outside so as to be convenient for placing a collected collection rod from the outside, a rectangular hole for the rotating disc to extend out is formed in the panel, an information identifier and a discharge hole are respectively arranged above the rectangular hole on the panel, a signal can be transmitted to a control end through the arrangement of the information identifier, the control end can control an internal delivery end to automatically pop up a collection rod at the moment, and a user can take out the collection rod to sample oral mucosa according to instructions; a vertical transmission rod is fixed in the middle of the lower surface of the rotating disc, a stepping motor is fixed below the transmission rod on the back surface of the panel, the rotating disc is in a central symmetry shape provided with six stations, six sliding extension blocks which are in central symmetry are arranged on the circumferential outer wall of the rotating disc, a collection rod clamping block is fixed on the upper surface of each sliding extension block, a T-shaped support is arranged on one side, far away from the panel, of the upper surface of the mounting plate, and a shearing device is arranged on the T-shaped support; the mounting plate is positioned below the shearing device and is provided with a detection rod collecting device for collecting the sheared collecting rods; through rotatory rolling disc and the collection stick fixture block of setting in rolling disc periphery edge corner, not only can put the collection stick after every use in order, take the collection pipe that holds the collection stick in medical personnel moreover between, there are the multichannel process, can effectively avoid medical personnel and the infection that is detected personnel's probably exists, the device is applicable to the higher sick appearance collection of infectivity.
The sliding and extending device is characterized in that a reducing cam with a round hole in the middle is fixed below a rotating disc on the upper surface of the mounting plate, one long-radius end of the reducing cam faces the rear side of the device, a gap is reserved between the inner wall of the round hole and the outer wall of a transmission rod, T-shaped pull rods extending to the center of the rotating disc are fixed on the lower surface of each sliding and extending block, a toggle rod is fixed on the lower surface of one end, far away from the sliding and extending block, of each T-shaped pull rod, a guide clamping frame matched with each T-shaped pull rod is fixed on the lower surface of the rotating disc, straight slot holes matched with the diameters of the toggle rods are formed in the guide clamping frame, extension springs are arranged between six corners of the lower surface of the rotating disc and the corresponding sliding and extending blocks, and spring baffles are fixed on the two ends of each extension spring; the setting of cooperation reducing cam makes the extension piece that rotating disk edge joint had the collection stick rotate to reducing cam long radius department and can be pushed away from rotating disk department, again handle the collection stick of centre gripping on collection stick fixture block this moment then reduce the degree of difficulty, also avoid influencing the collection stick of two adjacent stations.
The clamping centering device is arranged at the position, which is pointed by the long radius, of the reducing cam on the upper surface of the mounting plate, the collecting rod which is placed at will and is not centered is clamped to the middle position of a collecting rod clamping block, the later shearing of the head of the collecting rod is facilitated, the clamping centering device comprises a strip-shaped hole formed in the middle position, which is pointed by the long radius of the reducing cam, of the mounting plate, hinge plates which are parallel to each other are respectively fixed on the lower surface of the mounting plate, L-shaped swing supporting rods are rotatably connected between the bottom ends of the two hinge plates, groove-shaped sliding rails which are horizontally arranged and are provided with upward openings are fixedly arranged at the top ends of the L-shaped swing supporting rods, the whole body of the groove-shaped sliding rails is perpendicular to the plane of the panel, mutually symmetrical sliding blocks are respectively and slidably connected in the sliding grooves of the groove-shaped sliding rails, the two sliding blocks are rotatably connected with the same two bidirectional screw rods, one end of each groove-shaped sliding rail is fixedly provided with a servo motor, the output shaft ends of the servo motor are fixedly arranged at the end parts of the bidirectional screw rods, the upper surfaces of the two sliding blocks are fixedly provided with clamping plates which extend to the rotating plates, and are mutually parallel and vertically arranged; through the arrangement of the bidirectional screw rod, the two clamping plates can synchronously draw close to the middle, and then the collecting rods with different lengths at the two ends of the protruding collecting rod clamping block are extruded to the middle position.
The device is characterized in that a supporting block is fixed at the end part of the upper surface of the mounting plate, which is positioned at the strip-shaped hole, is positioned at one end far away from the rotating disc, a reset spring is fixed between the supporting block and the L-shaped swing supporting rod, a driving belt pulley is fixed at the top end of an output shaft of the stepping motor, a bearing seat is arranged on the lower surface of the mounting plate, which is close to the L-shaped swing supporting rod, a stepped shaft is rotatably connected at the bottom end of the bearing seat, an intermittent top wheel and a driven belt pulley are sequentially fixed on the circumferential outer wall of the stepped shaft, the same conveyor belt is wound between the circumferential outer walls of the driving belt pulley and the driven belt pulley, and a semi-cylinder is fixed in the middle of one side, which is close to the intermittent top wheel, of the L-shaped swing supporting rod; through intermittent type top wheel and reset spring's combination setting, when the collection stick is about to rotate to centre gripping centering device department, can be with the centre gripping centering device of fixing on L shape swing vaulting pole top short-term backward slope under intermittent type top wheel's effect, make room then and let the collection stick can not collide splint.
The device is further arranged in that a spring clamping block is fixed above the groove-shaped sliding rail and close to the middle, a pressure sensor is arranged on one side of the spring clamping block, close to the sliding block, of the groove-shaped sliding rail, the pressure sensor is connected with a processor through a signal wire, and a signal output end of the processor is connected with a control end of a servo motor through the signal wire; through the arrangement of the pressure sensor, the two clamping plates can automatically stop and reversely move to the original position after centering the collecting rod in the clamping centering process.
Further set up in, be located the top of rolling disc on the panel and be fixed with display screen and mirror, and the surface of panel is located the below of rolling disc and is fixed with the arc tray of arc platy structure, is provided with on the arc tray and turns to the indicator and gather the stick mode of putting, through display screen and the mirror that sets up, not only can display device's use step, can see through the mirror moreover and observe the oral cavity condition, convenient to use person oneself samples.
The automatic feeding device is further characterized in that a supporting frame with a groove structure is arranged at the position, located at the lower opening of the discharge opening, of the front face of the panel, a stepping conveyor belt is arranged on the back face of the panel, close to the upper side of the discharge opening, and the control end of the stepping conveyor belt is matched with the control end of the information identifier to be located in a control system; and after the information identifier reads the information and checks the information successfully, automatically controlling the stepping conveyor belt to pop up a collecting rod.
The shearing device is further arranged in that the shearing device further comprises an electric push rod fixed on the T-shaped support, the extending direction of the electric push rod extending rod is perpendicular to a collecting rod of a station where the electric push rod is located, a vertical sliding rail is fixed at the extending end of the electric push rod, a boss guide block is connected in a sliding way of the vertical sliding rail in a sliding way, a movable cutter and a fixed cutter which mutually form a scissor structure are respectively fixed on the side surfaces of the boss guide block and the vertical sliding rail, a compression spring I is fixed on the lower surface of the boss guide block, a spring support is fixed at the bottom of the compression spring I, a folding pull rod is fixed at the top end of the boss guide block, and an elastic triangular hook block is arranged at one end of the folding pull rod, which is far away from the boss guide block; a cantilever rod extending to the movable cutter is fixed on one side of the T-shaped support close to the rotating disc, and a horizontal stop lever matched with the back position of the movable cutter is fixed at the end part of the cantilever rod; through the setting of electric putter tip removal cutter, when gathering the stick and remove shearing mechanism department, only need control electric putter and carry out the flexible of round can cut the head of gathering the stick.
The elastic triangular hook block is further arranged in the way that a reset spring II is arranged below the elastic triangular hook block, which is far away from the hinge point, and the acquisition rod after being sheared can be pried away by matching with the oblique upward movement of the folding pull rod in the drawing-back stage of the extension rod of the electric push rod, so that the electric push rod can be used continuously in the later stage.
The detecting rod collecting device comprises a flaring receiving pipe fixed on the upper surface of the mounting plate and positioned below the horizontal stop rod, a detecting pipe collecting disc is rotatably connected with the lower surface of the mounting plate and positioned below the receiving pipe, a plurality of jacks are formed in the circumferential edge of the detecting pipe collecting disc, and collecting pipes with upward openings are inserted in the jacks; one side guard plate protrudes from the circumferential edge of the detection tube collecting disc, and a collecting bin is arranged on one side of the detection tube collecting disc, which is close to the detection tube collecting disc; the collection convenience of collecting the stick after cutting can be improved.
The anti-slip device is further characterized in that an arc-shaped groove is formed in the middle of the upper surface of the acquisition rod clamping block, U-shaped notches on a straight line are formed at two ends of the arc-shaped groove respectively, and anti-slip ribs are reserved between inner walls of two opposite sides of the U-shaped notches; the collecting rod can be clamped more easily, and is not easy to fall off in the transverse correcting process.
The beneficial effects of the invention are as follows:
1. through rotatory rolling disc and the collection stick fixture block of setting in rolling disc periphery edge corner, not only can put the collection stick after every use in order, take the collection pipe that holds the collection stick in medical personnel moreover between, there are the multichannel process, can effectively avoid medical personnel and the infection that is detected personnel's probably exists, the device is applicable to the higher sick appearance collection of infectivity.
2. Through the stirring rod and the direction card frame that set up, the setting of cooperation reducing cam makes the extension piece that rotating disk edge joint had the collection stick rotate to reducing cam long radius department can be pushed away from rotating disk department, again handle the collection stick of centre gripping on collection stick fixture block then reduce the degree of difficulty this moment, also avoid influencing the collection stick of two adjacent stations.
3. Through the arrangement of the bidirectional screw rod, the two clamping plates can synchronously draw close to the middle, and then the collecting rods with different lengths at the two ends of the protruding collecting rod clamping block are extruded to the middle position. 4. Through intermittent type top wheel and reset spring's combination setting, when the collection stick is about to rotate to centre gripping centering device department, can be with the centre gripping centering device of fixing on L shape swing vaulting pole top short-term backward slope under intermittent type top wheel's effect, make room then and let the collection stick can not collide splint.
Drawings
FIG. 1 is a schematic diagram showing the overall structure of an automatic sampling-based nucleic acid detecting apparatus according to the present invention;
FIG. 2 is a schematic diagram showing a rear structure of an automatic sampling-based nucleic acid detecting apparatus according to the present invention;
FIG. 3 is a top view showing the overall structure of an automatic sampling-based nucleic acid detecting apparatus according to the present invention;
FIG. 4 is a schematic diagram showing the structure of a detecting rod collecting device in an automatic sampling-based nucleic acid detecting apparatus according to the present invention;
FIG. 5 is a schematic diagram showing the structure of a rotating disc of an automatic sampling-based nucleic acid detecting apparatus according to the present invention;
FIG. 6 is a side view showing the structure of the lower surface of a rotating disk of an automatic sampling-based nucleic acid detecting apparatus according to the present invention;
FIG. 7 is a side view showing the structure of a shearing device in an automatic sampling-based nucleic acid detecting apparatus according to the present invention;
FIG. 8 is a schematic diagram showing the structure of a shearing device in an automatic sampling-based nucleic acid detecting apparatus according to the present invention;
FIG. 9 is a schematic diagram of a block structure of an automatic sampling-based nucleic acid detecting apparatus according to the present invention;
FIG. 10 is a side view of a shearing device in an automatic sampling-based nucleic acid detecting apparatus according to the present invention;
fig. 11 is a bottom view of a shearing device in an automatic sampling-based nucleic acid detecting apparatus according to the present invention when the shearing device is pushed open. In the figure: 1. a panel; 2. a display screen; 3. a rotating disc; 4. an arc-shaped tray; 5. a sliding extension block; 6. collecting a rod; 7. a support frame; 8. a discharge port; 9. a detection tube collection tray; 10. a collecting bin; 11. a side guard plate; 12. an information identifier; 13. clamping and centering device; 131. a clamping plate; 132. a slide block; 133. a slot-type slide rail; 134. abutting blocks; 135. a servo motor; 136. a spring clamping block; 137. a bidirectional screw; 138. a return spring; 139. a hinged plate; 140. l-shaped swing stay bars; 14. a mounting plate; 141. a bar-shaped hole; 15. a step conveyor belt; 16. a collection tube; 17. a collecting rod clamping block; 171. an arc-shaped groove; 172. a U-shaped notch; 173. an anti-slip rib; 18. a transmission rod; 19. a stepping motor; 20. a tension spring; 21. a T-shaped pull rod; 22. a toggle rod; 23. a guide clamping frame; 24. a spring baffle; 25. a variable diameter cam; 26. a straight slot; 27. a driving pulley; 28. a conveyor belt; 29. intermittent top wheel; 30. a T-shaped support; 31. a cantilever bar; 32. a horizontal stop lever; 33. an elastic triangular hook block; 34. a fold-shaped pull rod; 35. a vertical slide rail; 36. a boss guide block; 37. an electric push rod; 38. moving the cutter; 39. a fixed cutter; 40. a driven pulley.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments.
Referring to fig. 1-11, an automatic sampling-based nucleic acid detection device comprises a box shell with a cuboid structure as a whole, wherein a vertical panel 1 is reserved on the front surface of the box shell, side guard plates 11 parallel to each other are respectively fixed on two sides of the panel 1, a horizontally arranged mounting plate 14 is fixed in the middle of the back surface of the panel 1, a rotating disc 3 is rotatably connected to the mounting plate 14, the end part of the rotating disc 3 penetrates through the panel 1 to extend to the outer side so as to conveniently place a collected collection rod 6 from the outer side, a rectangular hole for the rotating disc 3 to extend is formed in the panel 1, an information identifier 12 and a discharge hole 8 are respectively arranged above the rectangular hole in the panel 1, signals can be transmitted to a control end through the arrangement of the information identifier 12, the control end can control the inner discharge end to automatically pop up one collection rod 6, and a user can take out the collection rod 6 according to instructions; a vertical transmission rod 18 is fixed in the middle of the lower surface of the rotating disc 3, a stepping motor 19 is fixed on the back surface of the panel 1 below the transmission rod 18, the rotating disc 3 is in a central symmetry shape provided with six stations, six sliding extension blocks 5 which are in central symmetry are arranged on the circumferential outer wall of the rotating disc 3, a collection rod clamping block 17 is fixed on the upper surface of each sliding extension block 5, a T-shaped support 30 is arranged on one side, away from the panel 1, of the upper surface of the mounting plate 14, and a shearing device is arranged on the T-shaped support 30; the mounting plate 14 is arranged below the shearing device and is provided with a detection rod collecting device for collecting the sheared collecting rods 6; through rotatory rolling disc 3 and set up the collection stick fixture block 17 at rolling disc 3 circumference edge corner, not only can put the collection stick 6 after every use in order, take the collection pipe 16 that holds collection stick 6 in medical personnel moreover between, there are the multichannel process, can effectively avoid medical personnel and by the infection that detects personnel's probably exists, the device is applicable to the higher sick appearance collection of infectivity.
Referring to fig. 5-6, a reducing cam 25 with a round hole in the middle is fixed below the upper surface rotating disc 3 of the mounting plate 14, one end with a long radius of the reducing cam 25 faces the rear side of the device, a gap is reserved between the inner wall of the round hole and the outer wall of the transmission rod 18, a T-shaped pull rod 21 extending towards the center of the rotating disc 3 is fixed on the lower surface of the sliding extension block 5, a toggle rod 22 is fixed on the lower surface of one end, far away from the sliding extension block 5, of the T-shaped pull rod 21, a guide clamping frame 23 mutually matched with each T-shaped pull rod 21 is fixed on the lower surface of the rotating disc 3, a straight slot hole 26 matched with the diameter of the toggle rod 22 is formed in the guide clamping frame 23, a tension spring 20 is arranged between six corners of the lower surface of the rotating disc 3 and the corresponding sliding extension block 5, and spring baffles 24 are fixed on two ends of the tension spring 20; the setting of cooperation reducing cam 25 makes the slip extension piece 5 that rotating disk 3 edge joint has collection stick 6 rotate to reducing cam 25 long radius department and can be pushed away from rotating disk 3 department, again handle the collection stick 6 of centre gripping on collection stick fixture block 17 then reduce the degree of difficulty this moment, also avoid influencing the collection stick 6 of two adjacent stations.
Referring to fig. 4-6, a clamping centering device 13 is arranged at the position of the long radius direction of the reducing cam 25 on the upper surface of the mounting plate 14, the acquisition rod 6 which is randomly placed and not centered is clamped at the center of the acquisition rod clamping block 17, the later shearing of the head of the acquisition rod 6 is facilitated, the clamping centering device 13 comprises a strip-shaped hole 141 which is formed in the middle position of the long radius direction of the reducing cam 25 on the mounting plate 14, hinge plates 139 which are parallel to each other are respectively fixed on the two sides of the strip-shaped hole 141 on the lower surface of the mounting plate 14, L-shaped swing supporting rods 140 are rotatably connected between the bottom ends of the two hinge plates 139, the top ends of the L-shaped swing supporting rods 140 are fixedly provided with groove-shaped sliding rails 133 which are horizontally arranged and are upwards opened, the whole body of the groove-shaped sliding rails 133 is perpendicular to the plane of the panel 1, two sliding blocks 132 which are symmetrically connected with each other in a sliding way are close to the two ends in the sliding way, the two sliding grooves of the groove-shaped sliding rails 133 are rotatably connected with the same two bidirectional screw rods 137, one end of the groove-shaped sliding rails 133 is fixedly provided with a servo motor 135, the output shaft ends of the servo motor 135 are fixedly arranged at the end parts of the bidirectional screw rods 137, the two upper surfaces of the two sliding rails 132 are fixedly provided with the clamping plates 131, and the two clamping plates 131 are vertically arranged in parallel to each other; through the arrangement of the bidirectional screw 137, the two clamping plates 131 can synchronously draw together towards the middle, and then the collecting rods 6 with different lengths at the two ends of the protruding collecting rod clamping block 17 are extruded to the middle position.
Referring to fig. 10, an abutment 134 is fixed to an upper surface of the mounting plate 14 at an end of the bar-shaped hole 141, the abutment 134 is positioned at an end far from the rotating disc 3, a return spring 138 is fixed between the abutment 134 and an L-shaped swing stay 140, a driving pulley 27 is fixed to a top end of an output shaft of the stepping motor 19, a bearing seat is arranged on a lower surface of the mounting plate 14 near the L-shaped swing stay 140, a stepped shaft is rotatably connected to a bottom end of the bearing seat, an intermittent top wheel 29 and a driven pulley 40 are sequentially fixed to a circumferential outer wall of the stepped shaft, the same conveyor belt 28 is wound between circumferential outer walls of the driving pulley 27 and the driven pulley 40, and a semi-cylinder is fixed to a middle of one side of the L-shaped swing stay 140 near the intermittent top wheel 29; through the combination arrangement of the intermittent top wheel 29 and the return spring, when the collecting rod 6 rotates to the clamping centering device 13, the clamping centering device 13 fixed at the top end of the L-shaped swing supporting rod 140 is inclined backwards for a short time under the action of the intermittent top wheel 29, and then space is made for the collecting rod 6 not to collide with the clamping plate 131.
Referring to fig. 5, a spring clamping block 136 is fixed above the groove-shaped sliding rail 133 near the middle, a pressure sensor is arranged on one side of the spring clamping block 136 near the sliding block 132, the pressure sensor is connected with a processor through a signal wire, and a signal output end of the processor is connected with a control end of the servo motor 135 through the signal wire; by means of the arrangement of the pressure sensor, the two clamping plates 131 can automatically stop and move reversely to the original position after centering the collecting rod 6 in the clamping centering process.
Referring to fig. 1-2, a display screen 2 and a mirror are fixed above a rotating disc 3 on a panel 1, an arc-shaped tray 4 with an arc-shaped plate structure is fixed below the rotating disc 3 on the surface of the panel 1, a steering indicator and a collection rod 6 are arranged on the arc-shaped tray 4, and through the arranged display screen 2 and mirror, the use steps of the device can be displayed, and the oral condition can be observed through the mirror, so that a user can sample the oral condition conveniently.
Referring to fig. 4, a supporting frame 7 with a groove structure is arranged at the position of the front surface of the panel 1, which is positioned at the lower opening of the discharge opening 8, and a stepping conveyor belt 15 is arranged at the back surface of the panel 1, which is close to the obliquely upper side of the discharge opening 8, and the control end of the stepping conveyor belt 15 is matched with the control end of the information identifier 12 to form a control system; after the information identifier 12 reads the information and checks it successfully, and automatically controls the stepping conveyor 15 to eject a pick-up bar 6.
Referring to fig. 7-8, the shearing device further comprises an electric push rod 37 fixed on the T-shaped support 30, the extending direction of the extending rod of the electric push rod 37 is mutually perpendicular to the collecting rod 6 of the station, a vertical slide rail 35 is fixed at the extending end of the electric push rod 37, a boss guide block 36 is connected in a sliding way of the vertical slide rail 35, a movable cutter 38 and a fixed cutter 39 which mutually form a scissor structure are respectively fixed on the side surfaces of the boss guide block 36 and the vertical slide rail 35, a compression spring I is fixed on the lower surface of the boss guide block 36, a spring bracket is fixed at the bottom end of the vertical slide rail 35 located at the compression spring I, a folded pull rod 34 is fixed at the top end of the boss guide block 36, and an elastic triangular hook block 33 is arranged at one end of the folded pull rod 34 away from the boss guide block 36; a cantilever rod 31 extending to the movable cutter 38 is fixed on one side of the T-shaped support 30 close to the rotating disc 3, and a horizontal stop lever 32 matched with the back position of the movable cutter 38 is fixed on the end part of the cantilever rod 31; through the setting of the mobile cutter 38 of electric putter 37 tip, when collection stick 6 moved shearing mechanism department, only need control electric putter 37 to carry out the flexible of round can cut the head of collection stick 6.
Referring to fig. 8, a second return spring is disposed below the elastic triangular hook block 33 far away from the hinge point, and can pry the cut collection rod 6 away in cooperation with the oblique upward movement of the folding pull rod 34 in the retraction stage of the extension rod of the electric push rod 37, so that the later-stage continuous use is facilitated.
Referring to fig. 2 and 4, the detecting rod collecting device comprises a flaring receiving pipe fixed on the upper surface of the mounting plate 14 and positioned below the horizontal stop rod 32, a detecting pipe collecting disc 9 is rotatably connected on the lower surface of the mounting plate 14 and positioned below the receiving pipe, a plurality of jacks are formed at the circumferential edge of the detecting pipe collecting disc 9, and collecting pipes 16 with upward openings are inserted into the jacks; one side guard plate 11 protrudes from the circumferential edge of the detection tube collecting disc 9, and a collecting bin 10 is arranged on one side of the detection tube collecting disc 9; the collection convenience of collecting the stick after cutting can be improved.
Referring to fig. 9, an arc groove 171 is formed in the middle of the upper surface of the collecting rod clamping block 17, two ends of the arc groove 171 are respectively provided with a U-shaped notch 172 on a straight line, and anti-slip ribs 173 are reserved between inner walls of two opposite sides of the U-shaped notch 172; the collecting rod 6 can be clamped more easily, and is not easy to fall off in the transverse correcting process.
When the device is used, a user firstly guides the two-dimension code of the identity card to the information identifier 12 or inputs the identity information through the display screen 2, and then automatically pops up a packaged acquisition rod 6 from the discharge port 8 after checking; after the user finishes the collection against the mirror, pressing the collection rod 6 on the two U-shaped notches 172 on the collection rod clamping block 17, clicking the completion on the display screen 2 at the moment, and rotating the rotating disc 3 by one grid at the moment, namely, rotating the collection rod 6 of the previous person to the inside of the panel 1 by thirty degrees; cross infection of the acquisition rod 6 is avoided; through the rotating disc 3 and the collecting rod clamping blocks 17 arranged at the corners of the circumferential edge of the rotating disc 3, not only can each used collecting rod 6 be placed in sequence, but also a plurality of working procedures exist between medical staff and the collecting tube 16 for containing the collecting rod 6, so that possible infection of the medical staff and detected staff can be effectively avoided; when the collecting rod 6 rotates to the rear, the collecting rod is propped against the clamping centering device 13 to be aligned under the action of the reducing cam 25; and then continuously rotating to rotate to the shearing device, and then shearing and collecting. The foregoing is only a preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art, who is within the scope of the present invention, should make equivalent substitutions or modifications according to the technical scheme of the present invention and the inventive concept thereof, and should be covered by the scope of the present invention.
Claims (4)
1. The utility model provides a nucleic acid detection equipment based on automatic sampling, includes the box shell that wholly is cuboid structure, and the front of box shell has reserved vertical panel (1), the both sides of panel (1) are fixed with side shield (11) that are parallel to each other respectively, and the back middle part of panel (1) is fixed with mounting panel (14) that the level set up, rotates on mounting panel (14) and is connected with rolling disc (3), and the tip of rolling disc (3) passes panel (1) and stretches out to the outside, is convenient for place collection stick (6) after gathering from the outside, open on panel (1) and have the rectangular hole that supplies rolling disc (3) to stretch out, and be provided with information identifier (12) and discharge gate (8) respectively above being located the rectangular hole on panel (1); the automatic feeding device is characterized in that a vertical transmission rod (18) is fixed in the middle of the lower surface of the rotating disc (3), a stepping motor (19) is fixed below the transmission rod (18) on the back surface of the panel (1), the rotating disc (3) is in a central symmetry shape provided with six stations, six sliding extension blocks (5) which are central symmetry are arranged on the outer circumferential wall of the rotating disc (3), a collection rod clamping block (17) is fixed on the upper surface of each sliding extension block (5), a T-shaped support (30) is arranged on one side, far away from the panel (1), of the upper surface of the mounting plate (14), and a shearing device is arranged on the T-shaped support (30); the mounting plate (14) is positioned below the shearing device and is provided with a detection rod collecting device; the shearing device further comprises an electric push rod (37) fixed on the T-shaped support (30), the extending direction of the electric push rod (37) is perpendicular to the collecting rod (6) of the station, a vertical sliding rail (35) is fixed at the extending end of the electric push rod (37), a boss guide block (36) is connected in a sliding way of the vertical sliding rail (35), a movable cutter (38) and a fixed cutter (39) which mutually form a scissor structure are respectively fixed on the side surfaces of the boss guide block (36), a compression spring I is fixed on the lower surface of the boss guide block (36), a spring bracket is fixed at the bottom end of the compression spring I, a folded pull rod (34) is fixed at the top end of the boss guide block (36), and an elastic triangular hook block (36) is arranged at one end of the folded pull rod (34) far away from the boss guide block; a cantilever rod (31) extending to the movable cutter (38) is fixed on one side of the T-shaped support (30) close to the rotating disc (3), and a horizontal stop lever (32) matched with the back position of the movable cutter (38) is fixed at the end part of the cantilever rod (31); a second reset spring is arranged below the elastic triangular hook block (33) far away from the hinge point;
the detecting rod collecting device comprises a flaring receiving pipe which is fixed on the upper surface of the mounting plate (14) and is positioned below the horizontal stop rod (32), a detecting pipe collecting disc (9) is rotatably connected with the lower surface of the mounting plate (14) and positioned below the receiving pipe, a plurality of jacks are formed in the circumferential edge of the detecting pipe collecting disc (9), and collecting pipes (16) with upward openings are inserted into the jacks; one side guard plate (11) protrudes from the circumferential edge of the detection tube collecting disc (9), and a collecting bin (10) is arranged on one side, close to the detection tube collecting disc (9);
a reducing cam (25) with a round hole in the middle is fixed below the upper surface rotating disc (3) of the mounting plate (14), one long radius end of the reducing cam (25) faces the rear side of the device, a gap is reserved between the inner wall of the round hole and the outer wall of the transmission rod (18), T-shaped pull rods (21) extending to the center of the rotating disc (3) are fixed on the lower surface of the sliding extension block (5), toggle rods (22) are fixed on the lower surface of one end, far away from the sliding extension block (5), of each T-shaped pull rod (21), guide clamping frames (23) matched with the diameter of each T-shaped pull rod (21) are fixed on the lower surface of the rotating disc (3), straight slot holes (26) matched with the diameters of the toggle rods (22) are formed in the guide clamping frames (23), extension springs (20) are arranged between six corners of the lower surface of the rotating disc (3) and the corresponding sliding extension block (5), and spring baffles (24) are fixed on two ends of each extension spring (20);
the upper surface of the mounting plate (14) is positioned at the long-radius directional position of the variable-diameter cam (25), the clamping centering device (13) comprises a strip-shaped hole (141) formed in the middle position of the long-radius directional position of the variable-diameter cam (25) of the mounting plate (14), hinge plates (139) which are parallel to each other are respectively fixed on two sides of the strip-shaped hole (141) on the lower surface of the mounting plate (14), L-shaped swing supporting rods (140) are rotationally connected between the bottom ends of the two hinge plates (139), groove-shaped sliding rails (133) which are horizontally arranged and are upward in opening are fixed on the top ends of the L-shaped swing supporting rods (140), the whole body of the groove-shaped sliding rails (133) is perpendicular to the plane where the panel (1) is positioned, mutually symmetrical sliding blocks (132) are respectively and slidingly connected to the two ends of the inside of the sliding grooves of the groove-shaped sliding rails (133), a same two bidirectional screw rod (137) are rotationally connected between the two sliding blocks (132), one end of each of the groove-shaped sliding rails (133) is fixedly provided with a servo motor (135), the output shaft ends of the servo motor (135) are fixedly arranged at the end parts of the two bidirectional screw rods (137), the two sliding plates (132) through a coupler, and the upper surfaces of the two sliding plates (131) are rotationally connected to the two clamping plates (3) and are rotationally parallel to each other;
the upper surface of the mounting plate (14) is fixed with a supporting block (134) at the end part of the strip-shaped hole (141), the supporting block (134) is positioned at one end far away from the rotating disc (3), a reset spring (138) is fixed between the supporting block (134) and the L-shaped swing supporting rod (140), a driving belt pulley (27) is fixed at the top end of an output shaft of the stepping motor (19), a bearing seat is arranged on the lower surface of the mounting plate (14) close to the L-shaped swing supporting rod (140), a stepped shaft is rotatably connected to the bottom end of the bearing seat, an intermittent top wheel (29) and a driven belt pulley (40) are sequentially fixed on the circumferential outer wall of the stepped shaft, the same conveyor belt (28) is wound between the circumferential outer walls of the driving belt pulley (27) and the driven belt pulley (40), and a semi-cylinder is fixed in the middle of one side of the L-shaped swing supporting rod (140) close to the intermittent top wheel (29);
through the combined arrangement of the intermittent top wheel (29) and the return spring, when the collection rod (6) rotates to the clamping centering device (13), the clamping centering device (13) fixed at the top end of the L-shaped swing supporting rod (140) is inclined backwards for a short time under the action of the intermittent top wheel (29), and then a space is reserved for the collection rod (6) not to collide with the clamping plate (131);
the middle part of the upper surface of the collecting rod clamping block (17) is provided with an arc groove (171), two ends of the arc groove (171) are respectively provided with a U-shaped notch (172) on a straight line, and anti-slip ribs (173) are reserved between the inner walls of two opposite sides of the U-shaped notch (172).
2. The automatic sampling-based nucleic acid detecting device according to claim 1, wherein a spring clamping block (136) is fixed above the groove-shaped sliding rail (133) near the middle part, a pressure sensor is arranged on one side of the spring clamping block (136) near the sliding block (132), the pressure sensor is connected with a processor through a signal wire, and a signal output end of the processor is connected with a control end of the servo motor (135) through a signal wire.
3. The automatic sampling-based nucleic acid detecting device according to claim 1, wherein a display screen (2) and a mirror are fixed above a rotating disc (3) on the panel (1), an arc-shaped tray (4) with an arc-shaped plate-shaped structure is fixed below the rotating disc (3) on the surface of the panel (1), and a steering indicator and a setting mode of a collecting rod (6) are arranged on the arc-shaped tray (4) through the arranged display screen (2) and the arranged mirror.
4. The automatic sampling-based nucleic acid detection device according to claim 1, wherein a supporting frame (7) with a groove-shaped structure is arranged at the position, located at the lower opening of the discharge opening (8), of the front surface of the panel (1), a stepping conveyor belt (15) is arranged on the back surface of the panel (1) and close to the obliquely upper side of the discharge opening (8), and the control end of the stepping conveyor belt (15) is matched with the control end of the information identifier (12) to form a control system.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211666385.6A CN116177114B (en) | 2022-12-23 | 2022-12-23 | Nucleic acid detection equipment based on automatic sampling |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211666385.6A CN116177114B (en) | 2022-12-23 | 2022-12-23 | Nucleic acid detection equipment based on automatic sampling |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN116177114A CN116177114A (en) | 2023-05-30 |
| CN116177114B true CN116177114B (en) | 2023-10-24 |
Family
ID=86445302
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211666385.6A Active CN116177114B (en) | 2022-12-23 | 2022-12-23 | Nucleic acid detection equipment based on automatic sampling |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN116177114B (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101502962A (en) * | 2009-02-23 | 2009-08-12 | 广州达意隆包装机械股份有限公司 | Individual object conveying device |
| CN112959039A (en) * | 2021-02-09 | 2021-06-15 | 义乌市环稠机械设备有限公司 | Syringe barrel needle assembly quality |
| CN113182591A (en) * | 2021-04-19 | 2021-07-30 | 长江精工钢结构(集团)股份有限公司 | Steel structural material cutting device with safety protection function |
| CN113729785A (en) * | 2021-09-15 | 2021-12-03 | 郁昌昇 | Novel sampling of long-range pharynx swab of coronavirus and automatic sample collection unit |
| CN215924343U (en) * | 2021-08-31 | 2022-03-01 | 武汉致远医疗科技有限公司 | Automatic spiral cover system of sampling pipe |
| CN115474969A (en) * | 2022-08-25 | 2022-12-16 | 上海大学 | A fully automatic non-contact nucleic acid sampling robot system |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8562274B2 (en) * | 2006-11-29 | 2013-10-22 | Pouch Pac Innovations, Llc | Load smart system for continuous loading of a pouch into a fill-seal machine |
-
2022
- 2022-12-23 CN CN202211666385.6A patent/CN116177114B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101502962A (en) * | 2009-02-23 | 2009-08-12 | 广州达意隆包装机械股份有限公司 | Individual object conveying device |
| CN112959039A (en) * | 2021-02-09 | 2021-06-15 | 义乌市环稠机械设备有限公司 | Syringe barrel needle assembly quality |
| CN113182591A (en) * | 2021-04-19 | 2021-07-30 | 长江精工钢结构(集团)股份有限公司 | Steel structural material cutting device with safety protection function |
| CN215924343U (en) * | 2021-08-31 | 2022-03-01 | 武汉致远医疗科技有限公司 | Automatic spiral cover system of sampling pipe |
| CN113729785A (en) * | 2021-09-15 | 2021-12-03 | 郁昌昇 | Novel sampling of long-range pharynx swab of coronavirus and automatic sample collection unit |
| CN115474969A (en) * | 2022-08-25 | 2022-12-16 | 上海大学 | A fully automatic non-contact nucleic acid sampling robot system |
Also Published As
| Publication number | Publication date |
|---|---|
| CN116177114A (en) | 2023-05-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN116177114B (en) | Nucleic acid detection equipment based on automatic sampling | |
| CN114848033A (en) | Automatic nucleic acid throat swab acquisition device | |
| CN110316223B (en) | Train running safety protection device running along rail | |
| CN113288287B (en) | Endoscope cutting anastomat with built-in monitoring probe of nail abutting seat | |
| CN212031508U (en) | Multifunctional full-automatic blood cell analyzer | |
| CN113558779B (en) | Needle tube collecting and processing equipment used after pediatric use in hospital | |
| CN115836885B (en) | Tumor biopsy forceps | |
| CN111661799A (en) | Uncapping mechanism | |
| CN110498253A (en) | A kind of storage of heparin tube and moving-out device and remove method | |
| CN112602755B (en) | Bamboo stick baking equipment for sausage string | |
| CN212326414U (en) | Clinical vacuum blood sampling device that uses of medical science inspection | |
| CN115137406A (en) | Self-service nucleic acid sampling chamber and self-service nucleic acid sampling method | |
| CN115517714A (en) | Portable nucleic acid acquisition auxiliary device | |
| CN209172520U (en) | A kind of highly-safe medical sampling box | |
| CN110498193B (en) | Wheel disc type blood collection tube storage and removal device and removal method | |
| CN221286511U (en) | Needle extractor | |
| CN211434551U (en) | Anesthesia syringe recovery plant | |
| CN211954872U (en) | Sampling device for air quality detection | |
| CN115400294B (en) | Full-automatic treatment device and method for medical syringe needle | |
| CN114486373A (en) | Sampling device for hyaluronic acid quality detection and use method thereof | |
| CN215780571U (en) | Transfusion device and transfusion bag separating device | |
| CN220111333U (en) | Serum separation and purification device | |
| CN116999333A (en) | Sputum sample collector for tuberculosis detection | |
| CN221814950U (en) | Needle head processor | |
| CN212831257U (en) | Discharging device for soft porcelain cooling equipment |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |