CN116172204A - Multi-vitamin mineral soft capsule - Google Patents
Multi-vitamin mineral soft capsule Download PDFInfo
- Publication number
- CN116172204A CN116172204A CN202310251522.8A CN202310251522A CN116172204A CN 116172204 A CN116172204 A CN 116172204A CN 202310251522 A CN202310251522 A CN 202310251522A CN 116172204 A CN116172204 A CN 116172204A
- Authority
- CN
- China
- Prior art keywords
- vitamin
- soft capsule
- capsule
- multivitamin
- biotin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000007901 soft capsule Substances 0.000 title claims abstract description 21
- 239000011707 mineral Substances 0.000 title claims abstract description 16
- 229910052500 inorganic mineral Inorganic materials 0.000 title claims abstract description 14
- 229940088594 vitamin Drugs 0.000 title claims description 7
- 239000011782 vitamin Substances 0.000 title claims description 7
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims abstract description 18
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 claims abstract description 16
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims abstract description 16
- 235000010755 mineral Nutrition 0.000 claims abstract description 15
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 claims abstract description 13
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims abstract description 10
- RMRCNWBMXRMIRW-BYFNXCQMSA-M cyanocobalamin Chemical compound N#C[Co+]N([C@]1([H])[C@H](CC(N)=O)[C@]\2(CCC(=O)NC[C@H](C)OP(O)(=O)OC3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)C)C/2=C(C)\C([C@H](C/2(C)C)CCC(N)=O)=N\C\2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O RMRCNWBMXRMIRW-BYFNXCQMSA-M 0.000 claims abstract description 10
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims abstract description 8
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims abstract description 8
- 229960000304 folic acid Drugs 0.000 claims abstract description 8
- 235000019152 folic acid Nutrition 0.000 claims abstract description 8
- 239000011724 folic acid Substances 0.000 claims abstract description 8
- 229960003512 nicotinic acid Drugs 0.000 claims abstract description 8
- 239000011664 nicotinic acid Substances 0.000 claims abstract description 8
- 235000001968 nicotinic acid Nutrition 0.000 claims abstract description 8
- 229910052711 selenium Inorganic materials 0.000 claims abstract description 8
- 239000011669 selenium Substances 0.000 claims abstract description 8
- 235000011649 selenium Nutrition 0.000 claims abstract description 8
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 claims abstract description 8
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 claims abstract description 5
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 claims abstract description 5
- 235000002414 D-alpha-tocopherylacetate Nutrition 0.000 claims abstract description 5
- 239000011740 D-alpha-tocopherylacetate Substances 0.000 claims abstract description 5
- 235000000638 D-biotin Nutrition 0.000 claims abstract description 5
- 239000011665 D-biotin Substances 0.000 claims abstract description 5
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims abstract description 5
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims abstract description 5
- CANRESZKMUPMAE-UHFFFAOYSA-L Zinc lactate Chemical compound [Zn+2].CC(O)C([O-])=O.CC(O)C([O-])=O CANRESZKMUPMAE-UHFFFAOYSA-L 0.000 claims abstract description 5
- FAPWYRCQGJNNSJ-UBKPKTQASA-L calcium D-pantothenic acid Chemical compound [Ca+2].OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O.OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O FAPWYRCQGJNNSJ-UBKPKTQASA-L 0.000 claims abstract description 5
- 229910000019 calcium carbonate Inorganic materials 0.000 claims abstract description 5
- 229960002104 cyanocobalamin Drugs 0.000 claims abstract description 5
- 239000011666 cyanocobalamin Substances 0.000 claims abstract description 5
- 235000000639 cyanocobalamin Nutrition 0.000 claims abstract description 5
- ZAKOWWREFLAJOT-UHFFFAOYSA-N d-alpha-Tocopheryl acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-UHFFFAOYSA-N 0.000 claims abstract description 5
- 229940039770 d-alpha-tocopheryl acetate Drugs 0.000 claims abstract description 5
- ZUFQODAHGAHPFQ-UHFFFAOYSA-N pyridoxine hydrochloride Chemical compound Cl.CC1=NC=C(CO)C(CO)=C1O ZUFQODAHGAHPFQ-UHFFFAOYSA-N 0.000 claims abstract description 5
- 229960004172 pyridoxine hydrochloride Drugs 0.000 claims abstract description 5
- 235000019171 pyridoxine hydrochloride Nutrition 0.000 claims abstract description 5
- 239000011764 pyridoxine hydrochloride Substances 0.000 claims abstract description 5
- 229960002477 riboflavin Drugs 0.000 claims abstract description 5
- 239000002151 riboflavin Substances 0.000 claims abstract description 5
- 235000019192 riboflavin Nutrition 0.000 claims abstract description 5
- 239000011576 zinc lactate Substances 0.000 claims abstract description 5
- 229940050168 zinc lactate Drugs 0.000 claims abstract description 5
- 235000000193 zinc lactate Nutrition 0.000 claims abstract description 5
- 239000011706 ferric diphosphate Substances 0.000 claims abstract description 4
- 235000007144 ferric diphosphate Nutrition 0.000 claims abstract description 4
- CADNYOZXMIKYPR-UHFFFAOYSA-B ferric pyrophosphate Chemical compound [Fe+3].[Fe+3].[Fe+3].[Fe+3].[O-]P([O-])(=O)OP([O-])([O-])=O.[O-]P([O-])(=O)OP([O-])([O-])=O.[O-]P([O-])(=O)OP([O-])([O-])=O CADNYOZXMIKYPR-UHFFFAOYSA-B 0.000 claims abstract description 4
- 229940036404 ferric pyrophosphate Drugs 0.000 claims abstract description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerol Substances OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 18
- 239000002775 capsule Substances 0.000 claims description 15
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims description 8
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 claims description 6
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 6
- 108010010803 Gelatin Proteins 0.000 claims description 6
- 235000010354 butylated hydroxytoluene Nutrition 0.000 claims description 6
- 229920000159 gelatin Polymers 0.000 claims description 6
- 239000008273 gelatin Substances 0.000 claims description 6
- 235000019322 gelatine Nutrition 0.000 claims description 6
- 235000011852 gelatine desserts Nutrition 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 5
- 239000008213 purified water Substances 0.000 claims description 5
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 4
- 235000020958 biotin Nutrition 0.000 claims description 4
- 239000011616 biotin Substances 0.000 claims description 4
- 229960002685 biotin Drugs 0.000 claims description 4
- 235000010216 calcium carbonate Nutrition 0.000 claims description 4
- 150000003904 phospholipids Chemical class 0.000 claims description 4
- 238000002360 preparation method Methods 0.000 claims description 4
- 239000004408 titanium dioxide Substances 0.000 claims description 4
- 235000010215 titanium dioxide Nutrition 0.000 claims description 4
- RBCOYOYDYNXAFA-UHFFFAOYSA-L (5-hydroxy-4,6-dimethylpyridin-3-yl)methyl phosphate Chemical compound CC1=NC=C(COP([O-])([O-])=O)C(C)=C1O RBCOYOYDYNXAFA-UHFFFAOYSA-L 0.000 claims description 3
- SPSPIUSUWPLVKD-UHFFFAOYSA-N 2,3-dibutyl-6-methylphenol Chemical compound CCCCC1=CC=C(C)C(O)=C1CCCC SPSPIUSUWPLVKD-UHFFFAOYSA-N 0.000 claims description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 3
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 claims description 3
- 229930003427 Vitamin E Natural products 0.000 claims description 3
- 235000019498 Walnut oil Nutrition 0.000 claims description 3
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims description 3
- 235000013871 bee wax Nutrition 0.000 claims description 3
- 239000012166 beeswax Substances 0.000 claims description 3
- 239000011575 calcium Substances 0.000 claims description 3
- 229910052791 calcium Inorganic materials 0.000 claims description 3
- 235000012730 carminic acid Nutrition 0.000 claims description 3
- FDJOLVPMNUYSCM-UVKKECPRSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2,7, Chemical compound [Co+3].N#[C-].C1([C@H](CC(N)=O)[C@@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)[N-]\C2=C(C)/C([C@H](C\2(C)C)CCC(N)=O)=N/C/2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O FDJOLVPMNUYSCM-UVKKECPRSA-L 0.000 claims description 3
- 239000002285 corn oil Substances 0.000 claims description 3
- 235000005687 corn oil Nutrition 0.000 claims description 3
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 3
- DTOSIQBPPRVQHS-PDBXOOCHSA-M linolenate Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC([O-])=O DTOSIQBPPRVQHS-PDBXOOCHSA-M 0.000 claims description 3
- 229940040452 linolenate Drugs 0.000 claims description 3
- 229940055726 pantothenic acid Drugs 0.000 claims description 3
- 235000019161 pantothenic acid Nutrition 0.000 claims description 3
- 239000011713 pantothenic acid Substances 0.000 claims description 3
- 235000019165 vitamin E Nutrition 0.000 claims description 3
- 229940046009 vitamin E Drugs 0.000 claims description 3
- 239000011709 vitamin E Substances 0.000 claims description 3
- 239000008170 walnut oil Substances 0.000 claims description 3
- 239000011701 zinc Substances 0.000 claims description 3
- 229910052725 zinc Inorganic materials 0.000 claims description 3
- 238000001035 drying Methods 0.000 description 6
- 239000003292 glue Substances 0.000 description 6
- 235000016709 nutrition Nutrition 0.000 description 5
- 230000035764 nutrition Effects 0.000 description 5
- 239000007788 liquid Substances 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 238000003756 stirring Methods 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 235000020256 human milk Nutrition 0.000 description 3
- 210000004251 human milk Anatomy 0.000 description 3
- 238000005096 rolling process Methods 0.000 description 3
- 239000007766 cera flava Substances 0.000 description 2
- 239000000084 colloidal system Substances 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000000227 grinding Methods 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 235000012054 meals Nutrition 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 239000012452 mother liquor Substances 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- 235000019198 oils Nutrition 0.000 description 2
- 239000000049 pigment Substances 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 238000007493 shaping process Methods 0.000 description 2
- 238000007873 sieving Methods 0.000 description 2
- 229930003231 vitamin Natural products 0.000 description 2
- 235000013343 vitamin Nutrition 0.000 description 2
- 235000005979 Citrus limon Nutrition 0.000 description 1
- 244000131522 Citrus pyriformis Species 0.000 description 1
- PMVSDNDAUGGCCE-TYYBGVCCSA-L Ferrous fumarate Chemical compound [Fe+2].[O-]C(=O)\C=C\C([O-])=O PMVSDNDAUGGCCE-TYYBGVCCSA-L 0.000 description 1
- 239000002313 adhesive film Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 229960003563 calcium carbonate Drugs 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000007872 degassing Methods 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000011773 ferrous fumarate Substances 0.000 description 1
- 235000002332 ferrous fumarate Nutrition 0.000 description 1
- 229960000225 ferrous fumarate Drugs 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000000873 masking effect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 235000021590 normal diet Nutrition 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 229940091258 selenium supplement Drugs 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
- A23L33/155—Vitamins A or D
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a multivitamin mineral soft capsule which comprises the following components: calcium carbonate, ferric pyrophosphate, selenium-enriched yeast, zinc lactate, D-alpha-tocopheryl acetate, nicotinic acid, D-calcium pantothenate, pyridoxine hydrochloride, riboflavin, folic acid, D-biotin, vitamin D 3 Cyanocobalamin. Compared with the prior art, the invention has the advantages that: provides a multivitamin mineral soft capsule with multivitamin and mineral nutrient elements, which improves the bioavailability.
Description
Technical Field
The invention relates to the technical field of capsules, in particular to a multi-vitamin mineral soft capsule.
Background
The nutrition elements needed by the human body for keeping healthy are mainly obtained through normal diet, but the nutrition for the adult, the pregnant woman and the breast milk crowd for keeping healthy is far insufficient through three meals a day, or the nutrition obtained by people from three meals a day is incomplete, because the nutrition elements which are lack of the human body are unknown for the adult, the pregnant woman and the breast milk crowd in different living environments or different health states, and how to reasonably supplement the nutrition in a targeted way is a problem which is not well solved by nutritionists until now.
The soft capsule package can quantitatively press and pack oily functional substances, functional substance solutions or functional substance suspensions, pastes or even functional substances into adhesive films to form sealed capsules with different sizes and shapes. Has the advantages of good light and oxygen isolation function, good visual effect, high bioavailability, accurate content, good uniformity, beautiful appearance, and the like, and is very suitable for packaging health-care food and the like.
The inclusion compound has the following advantages: masking bad smell and reducing irritation; the dissolution rate and bioavailability of the medicine are improved; improving the stability of the medicine.
There is no research on Guan Duowei biotin mineral soft capsules disclosed.
Disclosure of Invention
The technical problem to be solved by the invention is to overcome the technical defects and provide the multivitamin mineral soft capsule with multivitamin and mineral nutrient elements, so that the bioavailability is improved.
In order to solve the technical problems, the technical scheme provided by the invention is as follows: the multivitamin mineral soft capsule comprises the following components: calcium carbonate, ferric pyrophosphate, selenium-enriched yeast, zinc lactate, D-alpha-tocopheryl acetate, nicotinic acid, D-calcium pantothenate, pyridoxine hydrochloride, riboflavin, folic acid, D-biotin, vitamin D 3 Cyanocobalamin.
As an improvement, the composition further comprises auxiliary materials: gelatin, purified water, mono-, di-glycerol linolenate, glycerol, phospholipids, walnut oil, beeswax, titanium dioxide, carmine, corn oil, sunset yellow, dibutyl hydroxy toluene (BHT).
As an improvement, the content of the components in the capsule is 108mg of calcium, 2.76mg of iron, 2.13mg of zinc, 9ug of selenium and vitamin D 3 2ug, vitamin B 2 0.225mg, vitamin B 6 0.212mg, vitamin B 12 0.45ug, 1.4mg of nicotinic acid, 150ug of folic acid, 4.5g of biotin, 0.85mg of pantothenic acid and 3.6mg of vitamin E.
As an improvement, the capsule is prepared and packaged according to the manufacturing method of the capsule.
Compared with the prior art, the invention has the advantages that: the raw materials are easy to obtain, the prescription is more reasonable, the prescription is especially suitable for adults, pregnant women and breast milk people to take, vitamins and minerals necessary for the human body are timely supplemented, and the deficiency of vitamin intake often causes pathological changes of the organism and even endangers the life. However, excessive amounts also cause poisoning. The product reduces the components unsuitable for the dietary structure and constitution of Chinese in similar products, increases the components which should be supplemented, and has safer administration and better effect.
Detailed Description
The present invention will be described in further detail below.
The multi-vitamin mineral soft capsule is characterized in that: the composition comprises the following components: calcium carbonate, ferric pyrophosphate, selenium-enriched yeast, zinc lactate, D-alpha-tocopheryl acetate, nicotinic acid, D-calcium pantothenate, pyridoxine hydrochloride, riboflavin, folic acid, D-biotin, vitamin D 3 Cyanocobalamin.
The preparation method also comprises the following steps of: gelatin, purified water, mono-, di-glycerol linolenate, glycerol, phospholipids, walnut oil, beeswax, titanium dioxide, carmine, corn oil, sunset yellow, dibutyl hydroxy toluene (BHT).
The capsule contains calcium 108mg, ferrum 2.76mg, zinc 2.13mg, selenium 9ug and vitamin D 3 2ug, vitamin B 2 0.225mg, vitamin B 6 0.212mg, vitamin B 12 0.45ug, 1.4mg of nicotinic acid, 150ug of folic acid, 4.5g of biotin, 0.85mg of pantothenic acid and 3.6mg of vitamin E, and the raw materials are prepared according to the preparation method of capsules: heating oleum Juglandis to 60-70deg.C, adding Cera flava, stirring to melt Cera flava, stirring for 15 min to obtain oil wax mixture, and adding D-alpha-tocopheryl acetate and vitamin D 3 The oil, the mono-diglyceride, the phospholipid and the like are stirred and mixed to obtain a liquid mixture. Sequentially adding calcium carbonate, ferrous fumarate, zinc lactate, selenium-enriched yeast, riboflavin, pyridoxine hydrochloride, cyanocobalamin, nicotinic acid, folic acid, D-biotin and D-calcium pantothenate, mixing and stirring for 30 minutes, and grinding for 2-3 times by a colloid mill. Preparing a capsule shell: placing glycerol and purified water (1:1) into a stainless steel container, adding titanium dioxide, lemon yellow and sunset yellow, uniformly mixing, grinding for 2-3 times by a colloid mill, and sieving by a 100-mesh sieve to prepare pigment mother liquor. Heating the rest glycerol and purified water to 70-80deg.C, adding gelatin and pigment mother liquor, stirring until gelatin is completely dissolved, standing, vacuumizing, and degassing to obtain gelatin solutionNo air bubble; pressurizing to discharge the glue solution, sieving with a 100-mesh sieve, injecting the glue solution into a heat-preserving barrel, and preserving heat at 50-60 ℃ to obtain the glue solution. And (3) pelleting: the content and the capsule skin glue solution are conveyed into a glue storage tank of a soft capsule machine by a liquid conveying pipe and are kept warm. After the capsule core feed liquid and the capsule shell glue liquid are prepared, firstly adjusting the capsule shell thickness, starting to press soft capsules, controlling the weight of each content to be 1g, and controlling the environment between operations: the temperature is 18-26 ℃ and the relative humidity is less than or equal to 40 percent. Shaping: and conveying the pressed soft capsules into a rolling cage, and shaping for 2 hours along with the rolling of the rolling cage to cool and remove water on the surface of the soft capsules. Controlling the inter-operating environment: the temperature is 18-26 ℃ and the relative humidity is less than or equal to 40 percent. And (3) drying: and (3) conveying the soft capsules into a rotating cage drying or drying room for natural drying, controlling the ambient temperature of the drying room to be 18-26 ℃ and the relative humidity to be less than or equal to 30%, and drying for 18-30 hours under the condition. Pill selection: and (3) sorting out unqualified products from the dried soft capsules to obtain qualified soft capsules, and carrying out external packing: boxing, labeling, boxing, checking finished products and warehousing.
The invention, when embodied, is not described in detail in this specification, belongs to the prior art known to those skilled in the art.
The invention and its embodiments have been described above without limitation. In summary, if one of ordinary skill in the art is informed by this disclosure, a structural manner and an embodiment similar to the technical solution should not be creatively devised without departing from the gist of the present invention.
Claims (4)
1. The multi-vitamin mineral soft capsule is characterized in that: the composition comprises the following components: calcium carbonate, ferric pyrophosphate, selenium-enriched yeast, zinc lactate, D-alpha-tocopheryl acetate, nicotinic acid, D-calcium pantothenate, pyridoxine hydrochloride, riboflavin, folic acid, D-biotin, vitamin D 3 Cyanocobalamin.
2. The multivitamin mineral soft capsule of claim 1, wherein: the preparation method also comprises the following steps of: gelatin, purified water, mono-, di-glycerol linolenate, glycerol, phospholipids, walnut oil, beeswax, titanium dioxide, carmine, corn oil, sunset yellow, dibutyl hydroxy toluene (BHT).
3. The multivitamin mineral soft capsule of claim 1, wherein: the capsule contains calcium 108mg, ferrum 2.76mg, zinc 2.13mg, selenium 9ug and vitamin D 3 2ug, vitamin B 2 0.225mg, vitamin B 6 0.212mg, vitamin B 12 0.45ug, 1.4mg of nicotinic acid, 150ug of folic acid, 4.5g of biotin, 0.85mg of pantothenic acid and 3.6mg of vitamin E.
4. A multivitamin mineral soft capsule as claimed in claim 3, characterized in that: according to the preparation method of the capsule, the capsule is prepared and packaged by selecting the corresponding content ratio.
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| CN202310251522.8A CN116172204A (en) | 2023-03-16 | 2023-03-16 | Multi-vitamin mineral soft capsule |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102613543A (en) * | 2012-01-31 | 2012-08-01 | 哈尔滨顺亿堂医药生物科技开发有限公司 | Multi-vitamin and multi-mineral soft capsules |
| CN104719916A (en) * | 2013-12-18 | 2015-06-24 | 无锡伟康生物科技有限公司 | Multi-vitamin chewable tablets for pregnant women |
| CN105267236A (en) * | 2014-07-21 | 2016-01-27 | 常州制药厂有限公司 | Composite vitamin soft capsule |
| CN108851058A (en) * | 2018-07-13 | 2018-11-23 | 德瑞美医药生物技术盐城有限公司 | A kind of multivitamin minerals soft capsule and preparation method thereof rich in alpha-linolenic acid |
| CN111436616A (en) * | 2020-04-30 | 2020-07-24 | 新绎健康管理有限公司 | Composition containing vitamins and minerals |
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2023
- 2023-03-16 CN CN202310251522.8A patent/CN116172204A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102613543A (en) * | 2012-01-31 | 2012-08-01 | 哈尔滨顺亿堂医药生物科技开发有限公司 | Multi-vitamin and multi-mineral soft capsules |
| CN104719916A (en) * | 2013-12-18 | 2015-06-24 | 无锡伟康生物科技有限公司 | Multi-vitamin chewable tablets for pregnant women |
| CN105267236A (en) * | 2014-07-21 | 2016-01-27 | 常州制药厂有限公司 | Composite vitamin soft capsule |
| CN108851058A (en) * | 2018-07-13 | 2018-11-23 | 德瑞美医药生物技术盐城有限公司 | A kind of multivitamin minerals soft capsule and preparation method thereof rich in alpha-linolenic acid |
| CN111436616A (en) * | 2020-04-30 | 2020-07-24 | 新绎健康管理有限公司 | Composition containing vitamins and minerals |
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