CN116114611A - Animal basis biological information record case - Google Patents

Abstract

The invention provides an animal-based biological information recording box. The recording box comprises a drinking water counting assembly, a feeding basket assembly, an infrared thermal imaging camera assembly and an infrared monitoring camera assembly; the temperature change and feeding water inflow condition of the experimental animal are detected in real time through infrared temperature measurement, feed metering and drinking water counting, and an infrared camera is used for 24-hour video recording and is used for analyzing the movement capability of the experimental animal; the recording box has wide applicability, can be used for monitoring basic vital signs and basic behaviors of the disease states of mice, can be used for carrying out related research on the movement rhythms, and can also be used for monitoring the differences of the basic behaviors and vital signs of experimental mice with different experimental models, different strains and different genetic backgrounds; the animal-based biological information recording box has the advantages of simple structure, small volume, light weight and convenient movement. Most of the components can be disassembled and assembled, can be adapted to different equipment specifications of each laboratory, and are convenient to clean and replace.

Description

Animal basis biological information record case

Technical Field

The invention relates to the technical field of feeding equipment, in particular to an animal foundation biological information recording box.

Background

The mouse brain and the human brain have higher structural and functional similarity, can show social behaviors very similar to human, for example, the self-closing symptom model mouse can have the emotion and behavior changes of forced chewing, communication disorder, self-hair management, repeated nesting, irritability and the like, and is well fit with disease characteristics. The behavioral experiments can help scientific researchers to explore complex life phenomena such as cognition, emotion, movement and the like, and also help to understand and explore disease pathogenesis, so the behavioral experiments of rodents are an important means of neuroscience research.

The existing behavioral test method is mainly used for evaluating learning and memory, mental emotion, movement coordination capacity and the like of animal models, but basic vital signs and basic behaviors of experimental mice can be changed in some disease states besides the change of the emotion behaviors, for example, inflammatory model mice can show disease manifestations such as body temperature and weight reduction, feeding and water intake reduction, movement reduction and the like, however, the research on basic signs and basic behaviors of rodent experimental animals still lacks efficient monitoring means. Therefore, the development of a general behavior detection system which can be used for high-efficiency analysis and continuously monitoring the basic behavior and the basic behavior of rodents has wide application prospect.

The method for measuring the water intake of animals is a widely applied test method, can be used for monitoring the water intake of animals, and can further study the behaviors such as depression, addiction and the like by giving an aqueous sugar solution. Existing small animal water intake tests typically require manual weighing of the solution and cannot be automatically tested. The daily water intake of small animals is very small, and a small amount of mass loss in the manual weighing process causes a great error. For detecting the feed intake, a method for manually weighing the feed quality at fixed time is generally adopted, so that the efficiency is low, and time and labor are wasted. The common method for measuring the body temperature of the experimental animal is to manually measure the anus temperature, the experimental animal often struggles and is not easy to operate during operation, and the anus temperature measurement brings pain to the experimental animal. At present, the detection of the movement behaviors of rodents such as open field experiments and gait experiments is carried out by analyzing the movement in a certain time period, and an efficient, convenient and economic system for carrying out 24-hour movement monitoring on experimental animals is lacking in the market. The motion behavior of the experimental animal is captured and monitored, the traditional method is to mark the animal body, attach a bulb or a reflecting patch, the method is complex, and only a special laboratory can study the motion details in the process.

Disclosure of Invention

In view of the above, the present invention provides an animal-based bioinformation recording box to solve the technical problems in the prior art.

In a first aspect, the present invention provides an animal-based bioinformation recording box comprising:

a case;

the drinking water counting assembly is positioned in the box body and comprises a drinking water bottle and an infrared correlation counting sensor module, wherein the drinking water bottle is positioned in the box body, the bottle mouth of the drinking water bottle is inserted into a clamping groove of the infrared correlation counting sensor module, and the infrared correlation counting sensor module is used for recording the drinking water times of animals;

the feeding basket assembly is positioned in the box body and comprises a feeding basket positioned in the box body and a pressure sensor positioned at the bottom of the feeding basket, and the pressure sensor is used for detecting the quality of feed in the feeding basket;

the infrared thermal imaging camera component is positioned in the box body and is used for detecting the body temperature of an animal;

the infrared monitoring camera component is positioned in the box body and is used for shooting animal activity videos.

Preferably, the animal basic biological information recording box, a through hole is formed in a side wall of the box body, a bottle body of the drinking bottle is located outside the box body, and a bottle opening of the drinking bottle is inserted into a clamping groove of the infrared correlation counting sensor module through the through hole.

Preferably, the animal foundation biological information recording box, the infrared thermal imaging camera assembly comprises an infrared thermal imaging camera and a fastening bolt, and the infrared thermal imaging camera is fixed in the box body through the fastening bolt.

Preferably, the animal foundation biological information recording box, the infrared monitoring camera subassembly includes infrared monitoring camera and fastening bolt, infrared monitoring camera passes through fastening bolt fixes in the box.

Preferably, the animal-based biological information recording box, the pressure sensor is a resistance type film pressure sensor.

Preferably, the animal basic biological information recording box, the body of the drinking bottle is fixed on the outside of the box body through a drinking bottle fastener.

Preferably, the animal basic biological information recording box is characterized in that a plurality of ventilation holes are further formed in the side wall of the box body.

Preferably, the animal-based bioinformation recording box, the box body is made of transparent materials.

Preferably, the animal basic biological information recording box further comprises a computer processing unit, wherein the infrared correlation counting sensor module, the pressure sensor, the infrared thermal imaging camera component and the infrared monitoring camera component are electrically connected with the computer processing unit;

the infrared correlation counting sensor module, the pressure sensor, the infrared thermal imaging camera component and the infrared monitoring camera component transmit detected data to the computer processing unit.

Preferably, the animal-based bioinformation recording box, the computer processing unit is used for analyzing animal activity videos, and the analysis includes:

the computer processing unit identifies the body part of the animal and records the motion trail coordinate value of the animal;

the computer processing unit counts the animal movement distance, time length and speed;

and the computer processing unit counts the time period distribution of the spontaneous movement and the stationary phase of the animal and performs rhythm correlation analysis.

Compared with the prior art, the animal-based biological information recording box has the following beneficial effects:

1. the animal foundation biological information recording box comprises a drinking water counting assembly, a feeding basket assembly, an infrared thermal imaging camera assembly and an infrared monitoring camera assembly; the temperature change and feeding water inflow condition of the experimental animal are detected in real time through infrared temperature measurement, feed metering and drinking water counting, and an infrared camera is used for 24-hour video recording and is used for analyzing the movement capability of the experimental animal; the recording box has wide applicability, can be used for monitoring basic vital signs and basic behaviors of the disease states of mice, can be used for carrying out related research on the movement rhythms, and can also be used for monitoring the differences of experimental mice with different experimental models, different strains and different genetic backgrounds on the basic behaviors; the animal-based biological information recording box has the advantages of simple structure, small volume, light weight and convenient movement. Most of the components can be disassembled and assembled, can be adapted to different equipment specifications of each laboratory, and are convenient to clean and replace. The body temperature, feeding and water inflow monitoring means adopted by the technology can upload data in real time, so that data acquisition and trend statistics are facilitated. The device has flexibility in use, can be used for implementation of sugar water preference experiments only by replacing a drinking bottle, and can also be used for monitoring oral administration and feeding;

2. the animal basic biological information recording box comprises a computer processing unit, can automatically identify the body part of an experimental mouse, records the motion trail coordinate value of the mouse, can count the motion distance, the duration and the speed, can count the time period distribution of spontaneous motion and a resting stage, performs rhythm correlation analysis, and has free artificial intelligent core adopted during statistics, thus being extremely economical and efficient.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below. It is evident that the drawings in the following description are only some embodiments of the present invention and that other drawings may be obtained from these drawings without inventive effort for a person of ordinary skill in the art.

Fig. 1 is a schematic structural view of an animal-based bioinformation recording tank prepared in example 1.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention more clear, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention. It will be apparent that the described embodiments are some, but not all, embodiments of the invention. The components of the embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.

Thus, the following detailed description of the embodiments of the invention, as presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.

It should be noted that: like reference numerals and letters denote like items in the following figures, and thus once an item is defined in one figure, no further definition or explanation thereof is necessary in the following figures.

In the description of the present invention, it should be understood that, for the convenience of description and simplification of the description, it is not necessary to indicate or imply that the apparatus or elements referred to have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as limiting the invention, it is that the relation of orientation or position indicated as "upper" is based on the orientation or position relation shown in the drawings, or the orientation or position relation that is conventionally put when the inventive product is used, or the orientation or position relation that is conventionally understood by those skilled in the art.

The following description of the embodiments of the present invention will be made in detail and with reference to the embodiments of the present invention, but it should be apparent that the described embodiments are only some embodiments of the present invention, and not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the present invention without making any inventive effort, are intended to fall within the scope of the present invention.

An embodiment of the present invention provides an animal-based bioinformation recording box, as shown in fig. 1, including:

a case 1;

the drinking water counting assembly is positioned in the box body 1 and comprises a drinking water bottle 13 and an infrared correlation counting sensor module 6 which are positioned in the box body 1, the bottle mouth of the drinking water bottle 13 is inserted into a clamping groove of the infrared correlation counting sensor module 6, and the infrared correlation counting sensor module 6 is used for recording the drinking water times of animals;

the feeding basket assembly is positioned in the box body 1 and comprises a feeding basket 15 positioned in the box body 1 and a pressure sensor 8 positioned at the bottom of the feeding basket 15, wherein the pressure sensor 8 is used for detecting the quality of feed in the feeding basket 15;

the infrared thermal imaging camera component is positioned in the box body 1 and is used for detecting the body temperature of the animal;

the infrared monitoring camera component is positioned in the box body 1 and is used for shooting animal activity videos.

The animal foundation biological information recording box comprises a box body 1, and a drinking water counting assembly, a feeding basket assembly, an infrared thermal imaging camera assembly and an infrared monitoring camera assembly which are positioned in the box body 1; the bottle mouth of the drinking bottle 13 is inserted into the clamping groove of the infrared correlation counting sensor module 6, the infrared emission points and the receiving points on the elements of the infrared correlation counting sensor module 6 are arranged on two sides of the bottle mouth, the bottle mouth is slightly higher than the connection line of the infrared emission points and the receiving points, when an experimental animal such as a mouse drinks water once through licking the bottle mouth of the drinking bottle 13, the infrared rays below the bottle mouth are shielded, one-time counting is completed, and the total drinking frequency is uploaded to a computer in real time; the invention adopts the infrared drinking water counting technology, and by installing infrared emitting and receiving devices on two sides of the front end of the mouth of a drinking bottle, when an experimental animal licks the mouth of the bottle to drink water, the nose of the experimental animal shields infrared rays in front of the mouth of the bottle, and thus, one-time counting is completed. The drinking behavior of the mice is converted from water intake to drinking times, less errors are also more convenient to count, and the mice can count only by shielding infrared rays from the direction of the pipe orifice, so that the interference caused by the grabbing and climbing of the mice is greatly avoided, and the method for monitoring the drinking times of the small animals is a more accurate and convenient method for reflecting the drinking times of the small animals; compared with the conventional manual timing weighing of the feed quality, the feeding basket assembly provided by the invention has the advantages of low efficiency, time and labor waste, and the pressure sensor 8 can be used for detecting the residual feed quality in the feeding basket in real time, so that the problem that the weighing precision is influenced due to uneven measuring plane can be solved. The common method for measuring the body temperature of the experimental animal is to manually measure the anus temperature, the experimental animal often struggles and is not easy to operate during operation, and the anus temperature measurement brings pain to the experimental animal. According to the invention, the infrared temperature measuring camera is used for monitoring the body temperature of the experimental animal in real time, the data is uploaded to the computer in real time, the body temperature change trend can be counted, and compared with the traditional method for manually measuring the anal temperature, the method not only needs less manpower, but also obtains more detailed data.

The system can comprehensively monitor the basic behaviors of the experimental mice, detects the body temperature change and the feeding and water intake condition of the experimental animals in real time through infrared temperature measurement, feed metering and drinking counting, and the infrared camera records the video for 24 hours for analyzing the movement capability of the experimental animals; the technology has wide applicability, can be used for monitoring basic vital signs and basic behaviors of the disease states of mice, can be used for carrying out related research on the movement rhythms, and can also be used for monitoring the differences of experimental mice with different experimental models, different strains and different genetic backgrounds on the basic behaviors. At present, a plurality of devices for detecting movement and drinking water exist on the market, but the devices are mutually independent, and only statistics movement and drinking water are insufficient to fully reflect basic states of experimental animals, so that the technology unifies monitoring on four aspects of body temperature, feeding, water inlet and movement into a more complete system, and the detection on the basic states is more comprehensive and more convenient to use. The animal-based biological information recording box has the advantages of simple structure, small volume, light weight and convenient movement. Most of the components can be disassembled and assembled, can be adapted to different equipment specifications of each laboratory, and are convenient to clean and replace. The body temperature, feeding and water inflow monitoring means adopted by the technology can upload data in real time, so that data acquisition and trend statistics are facilitated. The device has flexibility in use, and can be used for implementation of sugar water preference experiments only by replacing the drinking bottle, and the feeding basket can also be used for monitoring oral administration and feeding.

In some embodiments, a through hole 5 is formed in one side wall of the box body 1, the body of the drinking bottle 13 is located outside the box body 1, and the bottle mouth of the drinking bottle 13 is inserted into the clamping groove of the infrared correlation counting sensor module 6 through the through hole 5.

Specifically, the box body 1 of the invention is hollow square, and the through hole 5 is arranged on the left side wall of the box body 1.

In some embodiments, the infrared thermal imaging camera assembly includes an infrared thermal imaging camera 10 and a fastening bolt 11, the infrared thermal imaging camera 10 being fixed within the case 1 by the fastening bolt.

In some embodiments, the infrared monitoring camera assembly includes an infrared monitoring camera 12 and a fastening bolt 11, and the infrared monitoring camera 12 is fixed in the case 1 by the fastening bolt 11.

Specifically, the infrared thermal imaging camera 10 and the infrared monitoring camera 12 of the invention are both fixed on the top wall 3 of the box body 1 through fastening bolts 11.

In some embodiments, the pressure sensor 8 is a resistive thin film pressure sensor.

In some embodiments, the body of the drinking bottle 13 is secured to the outside of the case 1 by a drinking bottle fastener 17.

In some embodiments, a plurality of ventilation holes 4 are further formed on the side wall of the case 1.

In some embodiments, the case 1 is made of a transparent material.

Specifically, six sides of the box body 1 are all made of transparent acrylic plates, so that light rays are ensured to enter the box body, and day and night lighting in the box body is realized. In fig. 1, the left side wall, the rear side wall 2 and the bottom plate 9 are all 250 x 250mm, and the size of the top wall 3 which can be detached independently is 300 x 300mm. The upper parts of the four side walls of the box body 1 are respectively provided with a plurality of ventilation holes 4, and a through hole 5 with the diameter of about 3.5cm is drilled at the position 10cm away from the bottom of the left side wall 1 of the box body for placing a drinking bottle 13 and an infrared correlation counting sensor module 6.

In some embodiments, the basket assembly is suspended by screws 14 on the rear side wall 2 of the case 1, the basket is a 10cm long iron fence-type food rack, the side view is square, the side is 6cm long, the bottom is provided with a resistive film pressure sensor, and a small hole 7 with the diameter of about 1cm is drilled on the rear side wall 2 of the case at a position 8cm away from the bottom for the resistive film pressure sensor 8 to transmit out.

In some embodiments, the infrared correlation counting system further comprises a computer processing unit, wherein the infrared correlation counting sensor module, the pressure sensor, the infrared thermal imaging camera assembly and the infrared monitoring camera assembly are electrically connected with the computer processing unit.

Specifically, the infrared thermal imaging camera data line is arranged on the outer side of the top wall and connected with the computer processing unit, and the infrared thermal imaging camera periodically transmits infrared imaging data to the computer processing unit.

In some embodiments, the infrared monitoring camera data line is arranged on the outer side of the top wall and connected with the computer processing unit, video shot by the infrared monitoring camera is recorded at 25 frames per second and 1080×720 resolution, continuous monitoring is carried out on the mouse activity in the box body 1 for 24 hours, and the circadian light rhythm does not influence imaging.

In some embodiments, the outgoing signal line from the pressure sensor 8 is sent out through a 1cm diameter small hole 7 in the rear sidewall 2 where the bottom edge of the basket is located, and is connected to a linear voltage conversion module 16 disposed outside the case 1, and then the data is transmitted to the computer processing unit.

In some embodiments, the animal-based bioinformation recording cases of the present invention further comprise a layer of padding laid on the bottom wall of the case.

In some embodiments, the side walls and the bottom of the periphery of the box body are acrylic plates, and every two plates are connected by acrylic special glue.

In some embodiments, the bottle mouth of the drinking bottle 13 and the infrared correlation counting sensor module 6 are about 8cm away from the bottom plate in the box body, and the animal can not influence counting when moving normally under the box body; the infrared correlation count sensor module 6 is the outward appearance of full-surrounded resin, and the resin material has high waterproof protection against rodents and stings the characteristic, and full-surrounded structure makes infrared ray be limited to the mouth of pipe below, is difficult for receiving the mouse to grab and climb the interference. Meanwhile, the side wall is only provided with a bottleneck and an infrared correlation counting sensor module, so that the possibility that the mouse climbs up and down to influence counting is greatly reduced. The distance between the emitting point and the receiving point of the infrared correlation counting sensor module 6 can be adjusted according to the diameters of the bottle mouths of different drinking bottles 13, and the adjustment range can meet the use requirements of most specifications of drinking bottles in the market.

In some embodiments, the iron wires forming the fence structure in the feeding basket are 2mm in diameter and 8mm in spacing, so that the mice can eat conveniently, and counting abnormality caused by falling of food can be avoided.

In some embodiments, the drinking bottle, the infrared correlation counting sensor module and the feeding basket are all detachable structures, so that the drinking bottle is convenient to clean and sterilize.

Specifically, the assembly process of the animal-based bioinformation recording box of the invention is as follows: the left side wall, the right side wall, the front side wall, the rear side wall 2 and the bottom plate 9 are respectively connected by acrylic special glue; an infrared thermal imaging camera 10 and an infrared monitoring camera 12 are fixed on the top wall 3 by a camera fastening bolt 11, and the circuits of the two cameras are directly connected with a computer processing unit; two screws 14 are fixed on the rear side wall 2 of the box body at intervals of 5cm, a feeding basket 15 is hung on the screws 14, a pressure sensor outgoing signal line is outgoing from a small hole 7 on the rear side wall and is connected with an external linear voltage conversion module 16; the bottle mouth of the drinking bottle 13 is fixed in the clamping groove of the infrared correlation counting sensor module 6, the outgoing line of the infrared correlation counting sensor module 6 is directly connected to the computer processing unit, the bottle mouth of the drinking bottle 13 and the infrared correlation counting sensor module 6 extend into the box body through the through hole 5 on the left side wall, and the drinking bottle 13 is inversely fixed on the drinking bottle fastener 17 on the outer side of the box body; and the top wall 3 is completely covered on the four walls of the box body, thus completing the assembly of the animal basic biological information monitoring box.

Specifically, in practice, the drinking bottle can also enter the box body 1 through the through hole 5, the independent infrared correlation counting sensor module 6 is mutually clamped with the bottle mouth of the drinking bottle, and the outgoing line of the infrared correlation counting sensor module 6 is connected with the receiving component outside the box body through the through hole.

In some embodiments, the computer processing unit is configured to analyze the animal activity video, the analysis comprising:

the computer processing unit identifies the body part of the animal and records the motion trail coordinate value of the animal;

the computer processing unit counts the animal movement distance, duration and speed;

and the computer processing unit counts the time period distribution of the spontaneous movement and the stationary phase of the animal and performs rhythm correlation analysis.

Specifically, the computer processing unit includes a machine learning based computer vision software package deep labcut deep learning software analysis video. Deep Labcut deep learning software is applied, and when the deep Labcut deep learning software is used for the first time, the deep Labcut needs to be trained and checked, and can be used for analyzing related test videos. A section of test video is randomly selected, 120 frames are randomly extracted from the test video, and an experimenter marks a specific body part of an experimented animal, such as a nose part, on each frame manually. Of these single frames, 90% were used for software training and 10% were used for verification of software identification prediction accuracy. Coordinate data of the marked part at each time point and corresponding prediction confidence degrees can be obtained after analysis by the DeepLabcut software. If the used model has high accuracy, the model can be used for test video analysis, and if the accuracy is lower, manual marking, retraining and inspection are needed to be carried out again. The trained and checked deep Labcut can be used for analyzing related test videos. The coordinate values (X, Y) of the pixel points of each frame of the marked part can be obtained through the DeepLabcut, and the coordinate data are synchronized to Python for analysis. As described above, the camera, which is externally arranged in the box for 24 hours and monitors and records, records at a frame rate of 25 frames per second, and the time difference between the frames can be calculated according to the number of each frame. Knowing that the bottom edge length of the box body is 250mm, the coordinate position change can be converted into the real distance through conversion between the pixel points and the real distance, so that the moving distance is counted. Thus, the movement data of the mice can be recorded and analyzed, including movement distance, duration, speed and the like. By analyzing the movement distance in a fixed time period, the movement state can be defined, if the movement distance exceeds 5cm in 30 seconds to be a spontaneous movement state and does not exceed 5cm to be a static state, the movement and static distinction can be realized, and the spontaneous movement and static time distribution situation is obtained and used for rhythm analysis.

The deep neural network for marking and predicting the animal body part by the deep learning software package deep Labcut needs to be trained in advance, the NVIDIA GeForce RTX 2080SUPER graphic processing unit is used for carrying out 30 ten thousand iterative training, 25000 iterative refining training is carried out, the training error of the network is 1.85 pixels, and the test error is 2.59 pixels. This network was used to analyze the video of all trials.

The foregoing description of the preferred embodiments of the invention is not intended to be limiting, but rather is intended to cover all modifications, equivalents, alternatives, and improvements that fall within the spirit and scope of the invention.

Claims (10)

1. An animal-based bioinformation recording case, comprising:

a case;

the drinking water counting assembly is positioned in the box body and comprises a drinking water bottle and an infrared correlation counting sensor module, wherein the drinking water bottle is positioned in the box body, the bottle mouth of the drinking water bottle is inserted into a clamping groove of the infrared correlation counting sensor module, and the infrared correlation counting sensor module is used for recording the drinking water times of animals;

the feeding basket assembly is positioned in the box body and comprises a feeding basket positioned in the box body and a pressure sensor positioned at the bottom of the feeding basket, and the pressure sensor is used for detecting the quality of feed in the feeding basket;

the infrared thermal imaging camera component is positioned in the box body and is used for detecting the body temperature of an animal;

the infrared monitoring camera component is positioned in the box body and is used for shooting animal activity videos.

2. The animal-based bioinformation recording box of claim 1, wherein a through hole is formed in a side wall of the box body, a body of the drinking bottle is located outside the box body, and a bottle mouth of the drinking bottle is inserted into a clamping groove of the infrared correlation counting sensor module through the through hole.

3. The animal-based bioinformation recording box of claim 1, wherein the infrared thermal imaging camera assembly comprises an infrared thermal imaging camera and a fastening bolt, the infrared thermal imaging camera being secured within the box by the fastening bolt.

4. The animal-based bioinformation recording case of claim 1, wherein the infrared monitoring camera assembly includes an infrared monitoring camera and a fastening bolt, the infrared monitoring camera being fixed in the case by the fastening bolt.

5. The animal-based bioinformation recording box of claim 1, wherein the pressure sensor is a resistive film pressure sensor.

6. The animal-based bioinformation recording case of claim 2, wherein the body of the drinking bottle is secured to the outside of the case by drinking bottle fasteners.

7. The animal-based bioinformation recording case of claim 1, wherein a plurality of ventilation holes are further formed in the sidewall of the case body.

8. The animal-based bioinformation recording case of claim 1, wherein said case is made of a transparent material.

9. The animal-based bioinformation recording box of any one of claims 1 to 8, further comprising a computer processing unit, wherein the infrared correlation count sensor module, the pressure sensor, the infrared thermal imaging camera assembly, and the infrared monitoring camera assembly are all electrically connected with the computer processing unit;

the infrared correlation counting sensor module, the pressure sensor, the infrared thermal imaging camera component and the infrared monitoring camera component transmit detected data to the computer processing unit.

10. The animal-based bioinformation recording box of claim 9, wherein the computer processing unit is configured to analyze animal activity videos, the analysis comprising:

the computer processing unit identifies the body part of the animal and records the motion trail coordinate value of the animal;

the computer processing unit counts the animal movement distance, time length and speed;

and the computer processing unit counts the time period distribution of the spontaneous movement and the stationary phase of the animal and performs rhythm correlation analysis.

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