CN116077407A - Eye health care massage composition, preparation method and application thereof - Google Patents
Eye health care massage composition, preparation method and application thereof Download PDFInfo
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- CN116077407A CN116077407A CN202211356465.1A CN202211356465A CN116077407A CN 116077407 A CN116077407 A CN 116077407A CN 202211356465 A CN202211356465 A CN 202211356465A CN 116077407 A CN116077407 A CN 116077407A
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- VBEQCZHXXJYVRD-GACYYNSASA-N uroanthelone Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(C)C)[C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CS)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(C)C)[C@@H](C)CC)C1=CC=C(O)C=C1 VBEQCZHXXJYVRD-GACYYNSASA-N 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- FJHBOVDFOQMZRV-XQIHNALSSA-N xanthophyll Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C=C(C)C(O)CC2(C)C FJHBOVDFOQMZRV-XQIHNALSSA-N 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
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- A—HUMAN NECESSITIES
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
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- A—HUMAN NECESSITIES
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/927—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of insects, e.g. shellac
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
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- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P27/02—Ophthalmic agents
- A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
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- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61Q19/00—Preparations for care of the skin
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Abstract
The invention discloses an eye health care massage composition, which comprises the following raw materials in parts by mass: 10-30 parts of plant component A, 1-5 parts of plant component B, 1-2 parts of pearl, 2-4 parts of vitamin, 2-5 parts of humectant, 1-2 parts of skin tightening agent, 1-2 parts of allantoin and 50-80 parts of ointment base. The eye health care massage composition prepared by the invention combines seven-acupoint thirteen-position manipulation massage to absorption, and has the functions of dredging meridian passage, promoting circulation and regulating intraocular pressure.
Description
Technical Field
The invention relates to the field of A61K8/9794, in particular to an eye health care massage composition, a preparation method and application thereof.
Background
Along with the acceleration of informatization application, work and study environment and life rhythm in the modern society, the popularization of mobile phones and electronic product screens leads to the long-time short-distance or fatigue eye use, blue light radiation, flickering of a screen and strong stimulation of light to eyes, and ciliary muscle adjustment and spasm, so that various eye discomfort symptoms of modern people, especially the problems of vision decline and the like of teenagers are caused to be more serious.
CN111067848A discloses an eye care essence for relieving asthenopia and preventing vision deterioration and a preparation method thereof, and the raw materials of the essence comprise a first plant component, a second plant component, a humectant and water; wherein the first plant component comprises flos Jasmini sambac, aloe, herba Setariae, and rhizoma Gastrodiae; the second plant component comprises Borneolum Syntheticum and ramulus Sambuci Williamsii. The invention mainly researches the storage stability of the essence and the curative effect on vision, and the borneol used in the components has certain allergy and irritation, certain sensitization risk and certain limitation on the use population.
CN 110742992a discloses a traditional Chinese medicine external composition for treating eyesight, which comprises fennel root bark, chamomile, butterflybush flower, magnetite, pipewort, feather cockscomb seed, mugwort leaf, cicada slough, safflower, cassia seed, white paeony root, turmeric, agilawood and peppermint.
In addition, the current market is mainly a means of 'post' remedy, the ophthalmic treatment is mainly western medicine treatment, and especially for the incidence of myopia of children and teenagers, there is almost no effective method for intervention in advance, and the development and application of 'pre' eye health care product technology are seriously lacking. The key development direction of eye health is "treating disease", and the composition conditioning health care through eye health care massage can promote ciliary muscle and extraocular muscle, promote the self regulation function of the eye circulatory system, promote the normal development and development of eyes, enable the whole eye system to trend to a healthy state, effectively prevent and prevent vision deterioration, and has better effect, safer and healthier effects.
Disclosure of Invention
In order to solve the problems, the invention discloses an eye health care massage composition, which comprises the following raw materials in parts by mass: 10-30 parts of plant component A, 1-5 parts of plant component B, 1-2 parts of pearl, 2-4 parts of vitamin, 2-5 parts of humectant, 1-2 parts of skin tightening agent, 1-2 parts of allantoin and 50-80 parts of ointment base.
Preferably, the composition is prepared from the following raw materials: 20-25 parts of plant component A, 2-4 parts of plant component B, 1.5-2 parts of pearl, 2-4 parts of vitamin, 3-4 parts of humectant, 1-2 parts of skin tightening agent, 1-2 parts of allantoin and 60-70 parts of ointment matrix.
Further preferably, the composition preparation raw materials include: 22 parts of plant component A, 3 parts of plant component B, 2 parts of pearl, 3 parts of vitamin, 4 parts of humectant, 2 parts of skin tightening agent, 2 parts of allantoin and 65 parts of ointment base.
In one embodiment, the plant component a is selected from one or more of olive leaf, aloe, gastrodia elata, borneol, cassia seed, honeysuckle, marigold flower, peppermint, medlar, dendrobium candidum leaf and kudzuvine root.
Preferably, the plant component A is a compound of aloe, cassia seed, peppermint, mulberry leaf and marigold flower, and the mass ratio is (1-2): (1-2): (2-4): (1-2): (2-5).
Further preferably, the plant component A is a compound of aloe, cassia seed, peppermint and marigold flowers, and the mass ratio is 2:1.5:3:1.5:4.
in one embodiment, the plant component B is selected from one or more of saffron, elder, polygonum aviculare, goosegrass, philippine flemingia root, mulberry leaf.
Preferably, the plant component B is a compound of saffron, polygonum aviculare and philippine flemingia root, and the mass ratio is (0.1-0.5): (1-3): (1-3).
Further preferably, the plant component B is a compound of saffron, polygonum aviculare and philippine flemingia root, and the mass ratio is 0.3:2:2.
the inventor creatively discovers in a large number of experimental processes that the absorption capacity can be improved and the drug effect can be improved by adding some plant components B for activating blood, especially adding saffron, polygonum aviculare and philippine flemingia root, and the mass ratio is controlled to be (0.1-0.5): (1-3): (1-3) and also increases the shelf life of the composition. The inventors believe that the possible reasons are: under the action of the plant component B, especially under the condition of hot compress, the vascular flow of eyes is increased, the microcirculation of eyes is improved, the absorption of various medicines is promoted, especially lutein ester extracted from marigold flowers is decomposed into free lutein after being absorbed by human bodies under the synergistic promotion of saffron, polygonum aviculare and philippine flemingia root, the density of macular pigment in the macular area of human eyes can be supplemented, the macula is protected, the macular development is promoted, the eyes are protected from being damaged by light, the aging and pathological changes of the eyes are delayed, the vision is protected, the asthenopia symptoms are relieved, and the problems of dark eyes and aging are reduced. In addition, under the synergistic effect of the three medicines, the antibacterial effect is achieved, and the shelf life of the composition is further prolonged.
In one embodiment, the pearl is a fresh water nano pearl powder with a particle size of 1000-2000 mesh.
Preferably, the fresh water nanometer pearl powder is purchased from Wuhan-Han-Kung-Bai pharmaceutical chemical Co., ltd, and the model is 1000 meshes.
In one embodiment, the vitamin is selected from one or more of vitamin a, vitamin C, vitamin E.
Preferably, the vitamin is a compound of vitamin A and vitamin E, and the mass ratio is (0.5-2): (1-2).
Further preferably, the mass ratio of the vitamin A to the vitamin E is 1:1.5.
in one embodiment, the humectant is selected from one or more of glycerol, 1, 2-pentanediol, sodium hyaluronate, joba oil, betaine, 1, 3-butanediol, ceramide acid, propylene glycol, trehalose, xylitol, and levan.
Preferably, the humectant is a compound of sodium hyaluronate and jojoba oil, and the mass ratio is (2-4): (1-3).
Further preferably, the humectant is a compound of sodium hyaluronate and jojoba oil, and the mass ratio is 3:2.
in one embodiment, the skin tightening agent is selected from one or more of a complex peptide, dextran, silk peptide.
Preferably, the skin tightening agent is silk peptide, which is purchased from Xiamen HongYao trade Limited.
In one embodiment, the ointment base is a oleaginous base.
Preferably, the oleaginous base is at least one selected from vaseline, paraffin wax, liquid paraffin, silicone, lanolin, and beeswax.
Further preferably, the oleaginous base is a compound of vaseline and beeswax, and the mass ratio is (3-10): 1.
The pearl powder can help to treat gastritis, calm and tranquilize, delay aging, clear liver and improve vision, but the dosage is not well controlled, the harm to the body is easy to occur, and the external application effect is obviously reduced. The inventors believe that the possible reasons are: the aloe contains unique protein, amino acid and polysaccharide substances, can easily break through skin barrier, the silk peptide is rich in epidermal growth factor, activates and improves microcirculation, contains natural humidifying factors, can keep the stratum corneum in an optimal moist state, and is easy to absorb, so that the fresh water nanometer pearl powder is combined with aloe under the moist effect of beeswax under the wrapping of beeswax, and penetrates into the skin to play roles of clearing liver and improving vision. Glaucoma and cataract are main blinding eye diseases in China, and at present, operation treatment can be carried out only after the disease is developed, and certain risks and sequelae risks exist before operation and during operation. The root cause of the induction is the daily lack of effective health care means of eyes, and the eye health care massage composition has the effects of promoting eye health, dredging channels and activating collaterals and regulating intraocular pressure in the aspect of optic nerve damage, thereby achieving the effect of reducing the incidence rate of complications such as cataract, glaucoma and the like, and having great significance for improving the blindness prevention level.
In another aspect, the invention discloses a method for preparing the composition, comprising the following steps:
s1: according to the mass portion, the plant component A is placed in an extraction tank for total, 10-12 times of water is added for soaking for 1-2 hours, the decoction is carried out for 0.5-1 hour, the plant component B is added for 0.5-1 hour, the decoction is filtered, and the ointment is concentrated for standby.
S2: adding the rest materials, stirring at 50-70deg.C, and making into composition.
Preferably, S1: placing the plant component A in an extraction tank for total, adding 10 times of water for soaking for 2 hours, decocting for 0.5 hour, adding the plant component B for decocting for 1 hour, filtering decoction, concentrating and collecting paste for later use.
S2: adding the rest materials, stirring at 60deg.C, and making into composition.
The composition can be applied to preparing eye care products in various forms such as eye ointment, eye essence and the like.
The beneficial effects are that:
1. the invention adds plant component A, which comprises aloe, cassia seed, peppermint, mulberry leaf and marigold flower in the mass ratio of (1-2): (1-2): (2-4): (1-2): (2-5) can moisten the skin of eyes, relieve discomfort of eyes and relieve fatigue of eyes.
2. The invention adds some plant component B with blood circulation promoting effect, which can improve absorption capacity and increase drug effect, especially adds saffron, polygonum aviculare and philippine flemingia root, and controls the mass ratio as (0.1-0.5): (1-3): (1-3) and also increases the shelf life of the composition.
3. The invention can obviously improve the efficacy of the pearl powder in clearing liver and improving eyesight by adding aloe, silk peptide and beeswax in the ointment matrix. The eye health care massage composition has the effects of promoting eye health, dredging channels and activating collaterals and regulating intraocular pressure in the aspect of optic nerve damage, thereby achieving the effect of reducing the incidence rate of complications such as cataract, glaucoma and the like, and having great significance for improving the blindness prevention level.
4. The vitamin A and the vitamin E are added, so that the medicine effect of the composition is more comprehensive, the composition can be used for teenagers, fatigue is relieved, vision deterioration is prevented, pseudomyopia can be reduced in degree, the composition can be used for adults, discomfort of eyes is relieved, and a certain anti-aging skin care effect is achieved.
5. The eye health-care massage composition prepared by the invention combines seven-acupoint thirteen-position manipulation massage to absorption, has the effects of clearing and activating the channels and collaterals, promoting circulation and regulating intraocular pressure, can quickly permeate into the tissue and blood circulation system of the eye periphery, thereby promoting the blood circulation of the whole eyeball, activating lacrimal glands, exciting the regulation and repair capacity of the eye circulation system, timely supplying nutrients needed by the eye muscles, dredging channels and collaterals, clearing stasis, enabling a large amount of metabolic wastes generated by abnormal contraction of the muscles to be timely discharged, regulating ciliary muscles, extraocular muscles, choroid and sclera, promoting the elasticity and tension of the eye wall, having obvious health-care effects on the eyesight of early myopia and middle-high myopia of the young children, effectively controlling the progress of the eye, and aiming at the adult, effectively relieving symptoms such as dry eye, dizziness, eye fatigue, eye discomfort and the like, and playing a role in regulating sub-health of the eye.
Detailed Description
Example 1
In one aspect, embodiment 1 discloses an eye health care massage composition, which is prepared from the following raw materials in parts by mass: 10 parts of plant component A, 5 parts of plant component B, 1 part of pearl, 2 parts of vitamin, 2 parts of humectant, 1 part of skin tightening agent, 2 parts of allantoin and 80 parts of oleaginous base.
The plant component A is a compound of aloe, cassia seed, peppermint, mulberry leaf and marigold flower, and the mass ratio is 1:2:4:1:5.
the plant component B is a compound of saffron, polygonum aviculare and philippine flemingia root, and the mass ratio is 0.1:3:1.
the pearl is fresh water nanometer pearl powder, and is purchased from Wuhan-Han-Kuinabai pharmaceutical chemical industry Co., ltd, and the model is 1000 meshes.
The vitamin is a compound of vitamin A and vitamin E, and the mass ratio is 0.5:2.
the humectant is a compound of sodium hyaluronate and jojoba oil, and the mass ratio is 2:1.
the skin tightening agent is silk peptide and is purchased from Xiamen HongYao trade Limited company.
The oleaginous matrix is a compound of vaseline and beeswax, and the mass ratio is 3:1.
in another aspect, this example 1 discloses a method of preparing the composition, comprising the steps of:
s1: placing the plant component A in an extraction tank for total, adding 12 times of water for soaking for 2 hours, decocting for 1 hour, adding the plant component B, decocting for 0.5 hour, filtering decoction, concentrating and collecting paste for later use.
S2: adding the rest materials, stirring at 50deg.C, and making into composition.
S3: the composition is applied to eye patch with hot compress function.
Example 2
In one aspect, embodiment 2 discloses an eye health care massage composition, which is prepared from the following raw materials in parts by mass: 30 parts of plant component A, 1 part of plant component B, 2 parts of pearl, 4 parts of vitamin, 5 parts of humectant, 2 parts of skin tightening agent, 1 part of allantoin and 50 parts of oleaginous base.
The plant component A is a compound of aloe, cassia seed, peppermint, mulberry leaf and marigold flower, and the mass ratio is 2:1:2:2:2.
the plant component B is a compound of saffron, polygonum aviculare and philippine flemingia root, and the mass ratio is 0.5:1:3.
the pearl is fresh water nanometer pearl powder, and is purchased from Wuhan-Han-Kuinabai pharmaceutical chemical industry Co., ltd, and the model is 1000 meshes.
The vitamin is a compound of vitamin A and vitamin E, and the mass ratio is 2:1.
the humectant is a compound of sodium hyaluronate and jojoba oil, and the mass ratio is 4:3.
the skin tightening agent is silk peptide and is purchased from Xiamen HongYao trade Limited company.
The oleaginous matrix is a compound of vaseline and beeswax, and the mass ratio is 10:1.
in another aspect, this example 2 discloses a method for preparing the composition, comprising the steps of:
s1: placing the plant component A in an extraction tank for total, adding 10 times of water for soaking for 1 hour, decocting for 0.5 hour, adding the plant component B for decocting for 1 hour, filtering decoction, concentrating to obtain paste for later use.
S2: adding the rest materials, stirring at 70deg.C, and making into composition.
S3: the composition is applied to eye patch with hot compress function.
Example 3
In one aspect, embodiment 3 discloses an eye care massage composition, which is prepared from the following raw materials in parts by mass: 22 parts of plant component A, 3 parts of plant component B, 2 parts of pearl, 3 parts of vitamin, 4 parts of humectant, 2 parts of skin tightening agent, 2 parts of allantoin and 65 parts of oleaginous base.
The plant component A is a compound of aloe, cassia seed, peppermint, mulberry leaf and marigold flower, and the mass ratio is 2:1.5:3:1.5:4.
the plant component B is a compound of saffron, polygonum aviculare and philippine flemingia root, and the mass ratio is 0.3:2:2.
the pearl is fresh water nanometer pearl powder, and is purchased from Wuhan-Han-Kuinabai pharmaceutical chemical industry Co., ltd, and the model is 1000 meshes.
The vitamin is vitamin A and vitamin E, and the mass ratio of the vitamin A to the vitamin E is 1:1.5.
the humectant is a compound of sodium hyaluronate and jojoba oil, and the mass ratio is 3:2.
the skin tightening agent is silk peptide and is purchased from Xiamen HongYao trade Limited company.
The oleaginous matrix is a compound of vaseline and beeswax, and the mass ratio is 6:1.
in another aspect, this example 3 discloses a method of preparing the composition, comprising the steps of:
s1: placing the plant component A in an extraction tank for total, adding 10 times of water for soaking for 2 hours, decocting for 0.5 hour, adding the plant component B for decocting for 1 hour, filtering decoction, concentrating and collecting paste for later use.
S2: adding the rest materials, stirring at 60deg.C, and making into composition.
S3: the composition is applied to eye patch with hot compress function.
Example 4
The embodiment 4 discloses an eye health care massage composition, which comprises the following raw materials in parts by mass: 22 parts of plant component A, 3 parts of plant component B, 5 parts of pearl, 3 parts of vitamin, 4 parts of humectant, 2 parts of skin tightening agent, 2 parts of allantoin and 30 parts of oleaginous base, and the rest is the same as in example 3.
Example 5
The plant component A is a compound of aloe, cassia seed, peppermint, mulberry leaf and marigold flower, and the mass ratio is 8:1:4:1:1, the plant component B is the combination of saffron, polygonum aviculare and philippine flemingia root, and the mass ratio is 4:1:1 and the rest are the same as in example 3.
Example 6
In one aspect, embodiment 6 discloses an eye care massage composition, which is prepared from the following raw materials in parts by mass: 22 parts of plant component A, 3 parts of plant component B, 2 parts of pearl, 3 parts of vitamin, 4 parts of humectant, 2 parts of skin tightening agent, 2 parts of allantoin and 65 parts of oleaginous base.
The plant component A is the composition of semen cassiae, honeysuckle, mint and marigold flowers, and the mass ratio is 1.5:3:1.5:4.
the plant component B is a compound of saffron, polygonum aviculare and philippine flemingia root, and the mass ratio is 0.3:2:2.
the pearl is fresh water nanometer pearl powder, and is purchased from Wuhan-Han-Kuinabai pharmaceutical chemical industry Co., ltd, and the model is 1000 meshes.
The vitamin is vitamin A and vitamin E, and the mass ratio of the vitamin A to the vitamin E is 1:1.5.
the humectant is a compound of sodium hyaluronate and jojoba oil, and the mass ratio is 3:2.
the skin tightening agent is glucan and is purchased from Xiamen HongYao trade Limited company.
The oleaginous base is vaseline.
In another aspect, this example 6 discloses a method of preparing the composition, comprising the steps of:
s1: placing the plant component A in an extraction tank for total, adding 10 times of water for soaking for 2 hours, decocting for 0.5 hour, adding the plant component B for decocting for 1 hour, filtering decoction, concentrating and collecting paste for later use.
S2: adding the rest materials, stirring at 60deg.C, and making into composition.
S3: the composition is applied to eye patch with hot compress function.
Performance test:
1. storage stability: after the compositions obtained in examples 1 to 6 were sealed and left at 40℃for 3 months, the presence or absence of delamination, caking and the like was observed, and the number of compositions free from deterioration was recorded for 100 samples of each example.
| Storage stability | |
| Example 1 | 98 |
| Example 2 | 99 |
| Example 3 | 100 |
| Example 4 | 14 |
| Example 5 | 79 |
| Example 6 | 90 |
2. And (3) safety detection: the sample of example 3 was subjected to a safety test according to QB/T2660-2004 technical Specification for cosmetic safety (2015 edition) with the following results:
and (1) microorganism detection: the total number of bacterial colonies, the total number of mould and saccharomycetes, the heat-resistant coliform group, staphylococcus aureus and pseudomonas aeruginosa are all in accordance with the requirements.
And (II) physical and chemical inspection: and the detection results of mercury, lead, arsenic, cadmium and dioxane all meet the requirements.
3. Toxicology test: the samples of example 3 were subjected to toxicological tests according to QB/T2660-2004 technical Specification for cosmetic safety (2015 edition) with the following results:
(one) results of multiple skin irritation tests: no irritation;
(II) acute eye irritation test results: has no irritation.
4. Example 3 was applied to 300 patients, with use case statistics from customer profiles, with 90% of the customers having no increase in myopia progression after use of the product, with more than 70% improvement 100 ° to 250 °,20% improvement 250 ° to 400 ° unequal, and 10% improvement over 400 °.
Claims (10)
1. The eye health care massage composition is characterized by comprising the following raw materials in parts by mass: 10-30 parts of plant component A, 1-5 parts of plant component B, 1-2 parts of pearl, 2-4 parts of vitamin, 2-5 parts of humectant, 1-2 parts of skin tightening agent, 1-2 parts of allantoin and 50-80 parts of ointment base.
2. The composition of claim 1, wherein the plant component a is selected from one or more of olive leaf, aloe, gastrodia elata, borneol, cassia seed, honeysuckle, marigold flower, peppermint, medlar, dendrobium candidum leaf, and kudzuvine root.
3. The composition according to claim 2, wherein the plant component a is a combination of aloe, cassia seed, peppermint, mulberry leaf and marigold flowers in a mass ratio of (1-2): (1-2): (2-4): (1-2): (2-5).
4. The composition of claim 1, wherein the plant component B is selected from one or more of saffron, elder, aviculare, goosegrass, philippine flemingia root, mulberry leaf.
5. The composition according to claim 4, wherein the plant component B is a combination of saffron crocus, polygonum aviculare and philippine flemingia root in a mass ratio of (0.1-05): (1-3): (1-3).
6. The composition of claim 1, wherein the pearl is a fresh water nano pearl powder having a particle size of 1000-2000 mesh.
7. The composition of claim 1, wherein the vitamin is selected from one or more of vitamin a, vitamin C, vitamin E.
8. The composition of claim 1, wherein the humectant is selected from one or more of glycerin, 1, 2-pentanediol, sodium hyaluronate, jojoba oil, betaine, 1, 3-butanediol, ceramide acid, propylene glycol, trehalose, xylitol, and levan.
9. A process for the preparation of a composition according to any one of claims 1 to 8, comprising the steps of:
s1: placing the plant component A in an extraction tank according to the parts by weight, adding 10-12 times of water, soaking for 1-2 hours, decocting for 0.5-1 hour, adding the plant component B, decocting for 0.5-1 hour, filtering decoction, concentrating and collecting paste for later use;
s2: adding the rest materials, stirring at 50-70deg.C, and making into composition.
10. Use of a composition according to any one of claims 1 to 8, for eye ointments, eye essences.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211356465.1A CN116077407A (en) | 2022-11-01 | 2022-11-01 | Eye health care massage composition, preparation method and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211356465.1A CN116077407A (en) | 2022-11-01 | 2022-11-01 | Eye health care massage composition, preparation method and application thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116077407A true CN116077407A (en) | 2023-05-09 |
Family
ID=86187554
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211356465.1A Withdrawn CN116077407A (en) | 2022-11-01 | 2022-11-01 | Eye health care massage composition, preparation method and application thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN116077407A (en) |
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2022
- 2022-11-01 CN CN202211356465.1A patent/CN116077407A/en not_active Withdrawn
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