CN116034263A - 用拉曼光谱分析病毒的方法 - Google Patents

用拉曼光谱分析病毒的方法 Download PDF

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Publication number
CN116034263A
CN116034263A CN202180052867.XA CN202180052867A CN116034263A CN 116034263 A CN116034263 A CN 116034263A CN 202180052867 A CN202180052867 A CN 202180052867A CN 116034263 A CN116034263 A CN 116034263A
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China
Prior art keywords
wavenumber
sample
viral
wavenumber ranges
vip
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Pending
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CN202180052867.XA
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English (en)
Chinese (zh)
Inventor
J·丘奇韦尔
M·O·巴拉迪兹
D·马歇尔
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Cell Therapy Catapult Ltd
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Cell Therapy Catapult Ltd
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Application filed by Cell Therapy Catapult Ltd filed Critical Cell Therapy Catapult Ltd
Publication of CN116034263A publication Critical patent/CN116034263A/zh
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G01J3/4412—Scattering spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/126—Microprocessor processing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/129—Using chemometrical methods
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/129—Using chemometrical methods
    • G01N2201/1296—Using chemometrical methods using neural networks

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN202180052867.XA 2020-07-01 2021-07-01 用拉曼光谱分析病毒的方法 Pending CN116034263A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB2010104.4A GB202010104D0 (en) 2020-07-01 2020-07-01 Method
GB2010104.4 2020-07-01
PCT/GB2021/051673 WO2022003359A1 (en) 2020-07-01 2021-07-01 Methods for analysing viruses using raman spectroscopy

Publications (1)

Publication Number Publication Date
CN116034263A true CN116034263A (zh) 2023-04-28

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ID=71949851

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180052867.XA Pending CN116034263A (zh) 2020-07-01 2021-07-01 用拉曼光谱分析病毒的方法

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Country Link
US (1) US20230236128A1 (https=)
EP (1) EP4176245A1 (https=)
JP (1) JP2023532568A (https=)
KR (1) KR20230028556A (https=)
CN (1) CN116034263A (https=)
AU (1) AU2021301333A1 (https=)
CA (1) CA3182045A1 (https=)
GB (1) GB202010104D0 (https=)
IL (1) IL299065A (https=)
WO (1) WO2022003359A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119964654A (zh) * 2025-04-09 2025-05-09 中国农业科学院北京畜牧兽医研究所 一种基于拉曼光谱的肌纤维类型分析方法、系统、设备及介质

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119264211A (zh) 2018-08-27 2025-01-07 瑞泽恩制药公司 拉曼光谱在下游纯化中的应用
US11726034B2 (en) * 2019-03-07 2023-08-15 Missouri State University IR spectra matching methods
US12422367B2 (en) 2021-11-19 2025-09-23 Janssen Biotech, Inc. Methods for determination of virus titer in a sample using Raman spectroscopy
CN119256220A (zh) 2022-05-23 2025-01-03 豪夫迈·罗氏有限公司 用于区分aav颗粒血清型和aav颗粒荷载状态的基于拉曼的方法
WO2024092247A1 (en) * 2022-10-27 2024-05-02 Hyperspectral Corp. Systems and methods for particle of interest detection
CN117783088B (zh) * 2024-02-23 2024-05-14 广州贝拓科学技术有限公司 激光显微拉曼光谱仪的控制模型训练方法及装置、设备
WO2025250834A1 (en) * 2024-05-31 2025-12-04 Thermo Scientific Portable Analytical Instruments Inc. Raman-based quality monitoring of biopharmaceutical production processes

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7940387B2 (en) * 2005-03-15 2011-05-10 Univeristy Of Georgia Research Foundation, Inc. Surface enhanced Raman spectroscopy (SERS) systems for the detection of viruses and methods of use thereof
US8712141B2 (en) * 2007-05-30 2014-04-29 Intelligent Virus Imagaing Inc. Method for counting and segmenting viral particles in an image
JP2020534829A (ja) * 2017-09-27 2020-12-03 ユニバーセルズ エス．エー．Ｕｎｉｖｅｒｃｅｌｌｓ Ｓ．Ａ． ウイルスワクチンなどの生体分子の製造システムおよび製造方法
GB2580186B (en) * 2018-12-24 2021-09-15 Cell Therapy Catapult Ltd Monitoring viral titre using Raman Spectroscopy

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119964654A (zh) * 2025-04-09 2025-05-09 中国农业科学院北京畜牧兽医研究所 一种基于拉曼光谱的肌纤维类型分析方法、系统、设备及介质

Also Published As

Publication number Publication date
JP2023532568A (ja) 2023-07-28
IL299065A (en) 2023-02-01
US20230236128A1 (en) 2023-07-27
EP4176245A1 (en) 2023-05-10
WO2022003359A1 (en) 2022-01-06
KR20230028556A (ko) 2023-02-28
GB202010104D0 (en) 2020-08-12
CA3182045A1 (en) 2022-01-06
AU2021301333A1 (en) 2023-02-02

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