CA3182045A1 - Methods for analysing viruses using raman spectroscopy - Google Patents

Methods for analysing viruses using raman spectroscopy

Info

Publication number
CA3182045A1
CA3182045A1 CA3182045A CA3182045A CA3182045A1 CA 3182045 A1 CA3182045 A1 CA 3182045A1 CA 3182045 A CA3182045 A CA 3182045A CA 3182045 A CA3182045 A CA 3182045A CA 3182045 A1 CA3182045 A1 CA 3182045A1
Authority
CA
Canada
Prior art keywords
viral
wavenumber
sample
wavenumber ranges
vip
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3182045A
Other languages
English (en)
French (fr)
Inventor
John CHURCHWELL
Marc Olivier BARADEZ
Damian Marshall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cell Therapy Catapult Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA3182045A1 publication Critical patent/CA3182045A1/en
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G01J3/4412—Scattering spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/126—Microprocessor processing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/129—Using chemometrical methods
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/129—Using chemometrical methods
    • G01N2201/1296—Using chemometrical methods using neural networks

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA3182045A 2020-07-01 2021-07-01 Methods for analysing viruses using raman spectroscopy Pending CA3182045A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB2010104.4A GB202010104D0 (en) 2020-07-01 2020-07-01 Method
GB2010104.4 2020-07-01
PCT/GB2021/051673 WO2022003359A1 (en) 2020-07-01 2021-07-01 Methods for analysing viruses using raman spectroscopy

Publications (1)

Publication Number Publication Date
CA3182045A1 true CA3182045A1 (en) 2022-01-06

Family

ID=71949851

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3182045A Pending CA3182045A1 (en) 2020-07-01 2021-07-01 Methods for analysing viruses using raman spectroscopy

Country Status (10)

Country Link
US (1) US20230236128A1 (https=)
EP (1) EP4176245A1 (https=)
JP (1) JP2023532568A (https=)
KR (1) KR20230028556A (https=)
CN (1) CN116034263A (https=)
AU (1) AU2021301333A1 (https=)
CA (1) CA3182045A1 (https=)
GB (1) GB202010104D0 (https=)
IL (1) IL299065A (https=)
WO (1) WO2022003359A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117783088A (zh) * 2024-02-23 2024-03-29 广州贝拓科学技术有限公司 激光显微拉曼光谱仪的控制模型训练方法及装置、设备

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119264211A (zh) 2018-08-27 2025-01-07 瑞泽恩制药公司 拉曼光谱在下游纯化中的应用
US11726034B2 (en) * 2019-03-07 2023-08-15 Missouri State University IR spectra matching methods
US12422367B2 (en) 2021-11-19 2025-09-23 Janssen Biotech, Inc. Methods for determination of virus titer in a sample using Raman spectroscopy
CN119256220A (zh) 2022-05-23 2025-01-03 豪夫迈·罗氏有限公司 用于区分aav颗粒血清型和aav颗粒荷载状态的基于拉曼的方法
WO2024092247A1 (en) * 2022-10-27 2024-05-02 Hyperspectral Corp. Systems and methods for particle of interest detection
WO2025250834A1 (en) * 2024-05-31 2025-12-04 Thermo Scientific Portable Analytical Instruments Inc. Raman-based quality monitoring of biopharmaceutical production processes
CN119964654B (zh) * 2025-04-09 2025-11-28 中国农业科学院北京畜牧兽医研究所 一种基于拉曼光谱的肌纤维类型分析方法、系统、设备及介质

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7940387B2 (en) * 2005-03-15 2011-05-10 Univeristy Of Georgia Research Foundation, Inc. Surface enhanced Raman spectroscopy (SERS) systems for the detection of viruses and methods of use thereof
US8712141B2 (en) * 2007-05-30 2014-04-29 Intelligent Virus Imagaing Inc. Method for counting and segmenting viral particles in an image
JP2020534829A (ja) * 2017-09-27 2020-12-03 ユニバーセルズ エス．エー．Ｕｎｉｖｅｒｃｅｌｌｓ Ｓ．Ａ． ウイルスワクチンなどの生体分子の製造システムおよび製造方法
GB2580186B (en) * 2018-12-24 2021-09-15 Cell Therapy Catapult Ltd Monitoring viral titre using Raman Spectroscopy

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117783088A (zh) * 2024-02-23 2024-03-29 广州贝拓科学技术有限公司 激光显微拉曼光谱仪的控制模型训练方法及装置、设备
CN117783088B (zh) * 2024-02-23 2024-05-14 广州贝拓科学技术有限公司 激光显微拉曼光谱仪的控制模型训练方法及装置、设备

Also Published As

Publication number Publication date
JP2023532568A (ja) 2023-07-28
IL299065A (en) 2023-02-01
US20230236128A1 (en) 2023-07-27
EP4176245A1 (en) 2023-05-10
WO2022003359A1 (en) 2022-01-06
KR20230028556A (ko) 2023-02-28
GB202010104D0 (en) 2020-08-12
CN116034263A (zh) 2023-04-28
AU2021301333A1 (en) 2023-02-02

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