CN1160108C

CN1160108C - Medicine for treating cholecystitis and its preparing process

Info

Publication number: CN1160108C
Application number: CNB021182795A
Authority: CN
Inventors: 孝孙; 孙孝
Original assignee: Individual
Current assignee: Individual
Priority date: 2002-05-01
Filing date: 2002-05-01
Publication date: 2004-08-04
Anticipated expiration: 2022-05-01
Also published as: CN1381265A

Abstract

The present invention discloses medicine for treating chelicystitis, which is prepared from twenty-four kinds of traditional Chinese medicine: bupleurum roots, angelica, hemlock parsley, cortex magnoliae officinalis from Sichuan of China, rhizomes of large-headed atractylodes, aucklandia roots, curcuma roots, Chinese yam, rhiizoma coptidis, malt, endothelium corneum gigeriae galli, lysimachia christinae, radix paeoniae alba, nutagrass flatsedge rhizom rice, aurantii, poria alba, pericarpium citri reticulatae, small green tangerine peels, fructus toosendan, fermented pinellia, haws, medicated leaven, rhizoma corydalis and liquorice. The traditional Chinese medicine is respectively processed with vinegar preparation, frying preparation, ginger preparation, baking preparation and roasting preparation; the traditional Chinese medicine is crushed, then mixed, and cured and sterilized in a proportion to obtain the powder medicine for treating cholecystitis. The present invention has obvious curative effect on treating acute and chronic cholecystitis.

Description

Medicine of treatment cholecystitis and preparation method thereof

Technical field

The present invention relates to a kind of medicine for the treatment of cholecystitis, specifically is the medicine of the treatment cholecystitis of feedstock production with the Chinese herbal medicine.The invention still further relates to the preparation method of this medicine.

Background technology

Cholecystitis is a kind of common frdquently encountered disease, in case morbidity pain is unbearably, and can't orthobiosis, work and rest.The medicine of existing treatment cholecystitis is many based on antibiotics, though these Western medicine are evident in efficacy, can alleviate patient's temporary transient pain, can not thoroughly effect a radical cure easy recurrence, moreover suffer from the concurrent cholelithiasis of cholecystitis meeting, gallbladder polyp for a long time, so the radical cure cholecystitis is very important.

Summary of the invention

The object of the present invention is to provide a kind of good effect, have no side effect, be difficult for the Chinese patent medicine of the treatment cholecystitis of recurrence.

Another object of the present invention provides the preparation method of the medicine of this treatment cholecystitis.

Solution of the present invention is on the basis of modern times to the cause of disease of cholecystitis, pathology understanding, according to clinical practice for many years, selects its elite to form from the hundreds of Chinese medicines of the medical treasure-house of motherland.

The formulation weight of active constituents of medicine of the present invention (part) ratio range is as follows:

Radix Bupleuri 25-35 Radix Angelicae Sinensis 9-19 Rhizoma Chuanxiong 6-16 Cortex Magnoliae Officinalis 8-18

Rhizoma Atractylodis Macrocephalae 10-20 Radix Aucklandiae 7-17 Radix Curcumae 9-19 Rhizoma Dioscoreae 11-21

Rhizoma Coptidis 12-22 Fructus Hordei Germinatus 10-20 Endothelium Corneum Gigeriae Galli 13-23 Herba Lysimachiae 25-35

Radix Paeoniae Alba 8-18 Rhizoma Cyperi 14-24 Fructus Aurantii 12-22 Poria 9-19

Pericarpium Citri Reticulatae 7-17 Pericarpium Citri Reticulatae Viride 8-18 Fructus Toosendan 11-21 Pinellia leaven 6-16

Fructus Crataegi 12-22 Massa Medicata Fermentata 11-21 Rhizoma Corydalis 9-19 Radix Glycyrrhizae 6-16

Formula optimization weight (part) ratio range of active constituents of medicine of the present invention is:

Radix Bupleuri 27-33 Radix Angelicae Sinensis 11-17 Rhizoma Chuanxiong 8-14 Cortex Magnoliae Officinalis 10-16

Rhizoma Atractylodis Macrocephalae 12-18 Radix Aucklandiae 9-15 Radix Curcumae 11-17 Rhizoma Dioscoreae 13-19

Rhizoma Coptidis 14-20 Fructus Hordei Germinatus 12-15 Endothelium Corneum Gigeriae Galli 15-21 Herba Lysimachiae 27-33

Radix Paeoniae Alba 10-16 Rhizoma Cyperi 16-22 Fructus Aurantii 14-20 Poria 11-17

Pericarpium Citri Reticulatae 9-15 Pericarpium Citri Reticulatae Viride 10-16 Fructus Toosendan 13-19 Pinellia leaven 8-14

Fructus Crataegi 14-20 Massa Medicata Fermentata 13-19 Rhizoma Corydalis 11-17 Radix Glycyrrhizae 8-14

Prescription optimum weight (part) proportioning of active constituents of medicine of the present invention is:

Radix Bupleuri 30 Radix Angelicae Sinensis 14 Rhizoma Chuanxiongs 11 Cortex Magnoliae Officinalis 13

The Rhizoma Atractylodis Macrocephalae 15 Radix Aucklandiae 12 Radix Curcumaes 14 Rhizoma Dioscoreaes 16

Rhizoma Coptidis 17 Fructus Hordei Germinatus 15 Endothelium Corneum Gigeriae Galli 18 Herba Lysimachiaes 30

The Radix Paeoniae Alba 13 Rhizoma Cyperis 19 Fructus Aurantiis 17 Porias 14

Pericarpium Citri Reticulatae 12 Pericarpium Citri Reticulatae Virides 13 Fructus Toosendans 16 Pinellia leavens 11

Fructus Crataegi 17 Massa Medicata Fermentata 16 Rhizoma Corydalis 14 Radix Glycyrrhizaes 11

Prepare the Radix Angelicae Sinensis body that the used Radix Angelicae Sinensis of medicine of the present invention preferably leaves out the beginning and the end.

Prepare the used Rhizoma Atractylodis Macrocephalae of medicine of the present invention and preferably adopt the wild Rhizoma Atractylodis Macrocephalae.

Produce in Radix Curcumae, the most handy Sichuan of Rhizoma Coptidis.Produce in the most handy Anhui of Rhizoma Dioscoreae.Produce in the most handy Hangzhou of the Radix Paeoniae Alba.

The method that preparation the present invention treats the medicine of gastropathy is:

1, mixes, treats Radix Bupleuri, the Radix Paeoniae Alba, Rhizoma Cyperi, Pericarpium Citri Reticulatae Viride, Fructus Aurantii thoroughly vinegar immerse the back and fry dried with slow fire with vinegar respectively;

2, with slow fire Radix Angelicae Sinensis, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Endothelium Corneum Gigeriae Galli, Massa Medicata Fermentata are fried to little yellow, Fructus Hordei Germinatus, Fructus Crataegi are fried to coke yellow;

3, with Pinellia leaven with clear water soak, cool half-dried after, add clear water, Rhizoma Zingiberis Recens and Alumen and boil to interior no Bai Xinhou airing;

4, the Radix Aucklandiae is cleaned vexed section airing with clear water, several layers separately in Radix Aucklandiae sheet and toilet paper are simmered as for the baking of stove room low baking temperature, and airing deoils;

5, with the above-mentioned drug powder that is mixed in proportion the cholecystitis that to obtain medical treatment through Chinese medicinal components and Rhizoma Chuanxiong, Cortex Magnoliae Officinalis, Radix Curcumae, Rhizoma Coptidis, Herba Lysimachiae, Poria, Pericarpium Citri Reticulatae, Fructus Toosendan, Rhizoma Corydalis, the pulverizing of Chinese medicine of licorice root component, the sterilization of the process of preparing Chinese medicine.

The medication medication that the present invention treats cholecystitis can adopt multiple dosage form, can make packed or bottled powder, also can make capsule, can also make honeyed pill, tablet etc.

The clinical drug application result that the present invention treats cholecystitis shows that following advantage is arranged: 1, medicine medicine of the present invention source is abundant, and cost is low.2, do not contain any toxic component, take for a long time human body is had no side effect.3, this medicine need not decoct, and can adopt powder, capsule, honeyed pill, tablets and other formulations, and taking convenience meets the national health law regulation.4, the present invention fills a prescription rationally, and drug effect is remarkable, cures the back and is difficult for recurrence.

Since nineteen eighty, the inventor treats example surplus the cholecystitis patient nearly 3000, and 160 examples are followed up a case by regular visits to and write down to inventor's random observation, and the patient all has upper right abdomen in various degree to continue dull pain or draw right omoplate district pain, abdominal part is vexed bloated discomfort often, belch pantothenic acid, nausea and vomiting, bitter taste, liver and gall district tenderness, after the food high fat diet that has obvious indigestion symptom and sign are arranged, all be diagnosed as acute and chronic cholecystitis through ultrasound diagnosis, observed result is as follows: man's 64 examples wherein, woman's 96 examples; 22 years old of age minimum, maximum 70 years old, 42.5 years old mean age; Medical history is the shortest 6 months, and is the longest 20 years, with 25 examples of cholelithiasis.Therapeutic outcome is as follows:

Recovery from illness: treat further consultation after 3 months, clinical symptoms and sign all disappear, and through the B ultrasonic check, gallbladder wall is smooth, and contractile function is normal, and calculus disappears, and liver and gall are no abnormal, add up to 54 examples, account for 33.8%.

Produce effects: treat further consultation after 3 months, clinical symptoms and sign all disappear, but through the B ultrasonic check, gallbladder wall still has and slightly thickens 0.4cm or crude, adds up to 98 examples, accounts for 61.2%.

Invalid: treat further consultation after 3 months, clinical symptoms and sign do not have improvement or increase the weight of, and add up to 8 examples, account for 5%.

Total effective rate 95% is not seen toxic and side effects and untoward reaction.

The specific embodiment

Model case 1: Liang Xiuying, the woman 53 years old, lives Chifeng City's Yuanbaoshan District five tame ore deposits, the workman.Go to a doctor the main suit on April 20th, 1997: upper right abdomen pain, draw right omoplate pain, detest oil with mild nausea, bitter taste, clinical indigestion symptom and sign such as abdominal part distension five days, have a medical check-up blood pressure 140/80mmHg, ill face, light red tongue, yellow and greasy fur, wiry and frequent pulse, be diagnosed as acute cholecystitis through B ultrasonic, gallbladder enlargement, wall thickness 0.7cm, patient takes medicine of the present invention, every day 3 times, each 5, advise eating attention to avoid cold and uncooked food, pungent, greasy, foods such as egg, 15 days is a course of treatment, take medicine after 3 courses of treatment further consultation on April 25 in 1997, clinical all sings and symptoms complete obiterations, patient's private prosecution does not have sense of discomfort, through B ultrasonic check liver and gall no abnormality seen.

Model case 2: Huang Shixun, the woman 42 years old, lives the flat village of Chifeng City's Yuanbaoshan District power supply administration family dependents' building, the workman of woollen mill.Go to a doctor main suit: back pain, bitter taste, abdominal part distension on March 28th, 2000, liver and gall district pain, clinical symptoms: blood pressure 140/80mmHg, yellow fur, wiry and frequent pulse, dyspepsia is diagnosed as the Qi-stagnation type chronic cholecystitis, and patient takes powder and capsule medicine of the present invention, every day 3 times, each 5,15 days is a course of treatment, take medicine after 3 courses of treatment further consultation on May 10 in 2000, clinical all sings and symptoms complete obiterations, patient's private prosecution does not have sense of discomfort, and is normal through B ultrasonic check liver and gall.

Embodiment

With preparation double centner medicated powder is example, 8.0 kilograms of Radix Bupleuri, 3.7 kilograms of Radix Angelicae Sinensis, 2.9 kilograms of Rhizoma Chuanxiongs, 3.4 kilograms of Cortex Magnoliae Officinalis, 3.9 kilograms of the Rhizoma Atractylodis Macrocephalaes, 3.2 kilograms of the Radix Aucklandiae, 3.7 kilograms of Radix Curcumaes, 4.2 kilograms of Rhizoma Dioscoreaes, 4.5 kilograms of Rhizoma Coptidis, 4.0 kilograms in Fructus Hordei Germinatus, 4.8 kilograms of Endothelium Corneum Gigeriae Galli, 7.9 kilograms of Herba Lysimachiaes, 3.4 kilograms of the Radix Paeoniae Albas, 5.0 kilograms of Rhizoma Cyperis, 4.5 kilograms of Fructus Aurantiis, 3.7 kilograms of Porias, 3.2 kilograms of Pericarpium Citri Reticulataes, 3.4 kilograms on Pericarpium Citri Reticulatae Viride, 4.2 kilograms of Fructus Toosendans, 3.0 kilograms of Pinellia leavens, 4.5 kilograms of Fructus Crataegis, 4.2 kilograms of Massa Medicata Fermentata, 3.7 kilograms of Rhizoma Corydalis, 3.0 kilograms in Radix Glycyrrhizae.Concoct purge drying respectively as stated above and be crushed to the mixing of 100 order fine powders, ripening sterilization, incapsulate and promptly make capsule Chinese medicine.

5 of the each clothes of adult, day clothes 3 times, 1-3 the course of treatment.

Claims

1, a kind of medicine for the treatment of cholecystitis is characterized in that what it was made by following raw medicaments in portion by weight: Radix Bupleuri 25-35, Radix Angelicae Sinensis 9-19, Rhizoma Chuanxiong 6-16, Cortex Magnoliae Officinalis 8-18, Rhizoma Atractylodis Macrocephalae 10-20, Radix Aucklandiae 7-17, Radix Curcumae 9-19, Rhizoma Dioscoreae 11-21, Rhizoma Coptidis 12-22, Fructus Hordei Germinatus 10-20, Endothelium Corneum Gigeriae Galli 13-23, Herba Lysimachiae 25-35, Radix Paeoniae Alba 8-18, Rhizoma Cyperi 14-24, Fructus Aurantii 12-22, Poria 9-19, Pericarpium Citri Reticulatae 7-17, Pericarpium Citri Reticulatae Viride 8-18, Fructus Toosendan 11-21, Pinellia leaven 6-16, Fructus Crataegi 12-22, Massa Medicata Fermentata 11-21, Rhizoma Corydalis 9-19, Radix Glycyrrhizae 6-16.

2, the medicine of treatment cholecystitis according to claim 1, wherein the weight portion of various crude drug is: Radix Bupleuri 27-33, Radix Angelicae Sinensis 11-17, Rhizoma Chuanxiong 8-14, Cortex Magnoliae Officinalis 10-16, Rhizoma Atractylodis Macrocephalae 12-18, Radix Aucklandiae 9-15, Radix Curcumae 11-17, Rhizoma Dioscoreae 13-19, Rhizoma Coptidis 14-20, Fructus Hordei Germinatus 12-15, Endothelium Corneum Gigeriae Galli 15-21, Herba Lysimachiae 27-33, Radix Paeoniae Alba 10-16, Rhizoma Cyperi 16-22, Fructus Aurantii 14-20, Poria 11-17, Pericarpium Citri Reticulatae 9-15, Pericarpium Citri Reticulatae Viride 10-16, Fructus Toosendan 13-19, Pinellia leaven 8-14, Fructus Crataegi 14-20, Massa Medicata Fermentata 13-19, Rhizoma Corydalis 11-17, Radix Glycyrrhizae 8-14.

3, the medicine of treatment cholecystitis according to claim 1, wherein the weight portion of various crude drug is: Radix Bupleuri 30, Radix Angelicae Sinensis 14, Rhizoma Chuanxiong 11, Cortex Magnoliae Officinalis 13, the Rhizoma Atractylodis Macrocephalae 15, the Radix Aucklandiae 12, Radix Curcumae 14, Rhizoma Dioscoreae 16, Rhizoma Coptidis 17, Fructus Hordei Germinatus 15, Endothelium Corneum Gigeriae Galli 18, Herba Lysimachiae 30, the Radix Paeoniae Alba 13, Rhizoma Cyperi 19, Fructus Aurantii 17, Poria 14, Pericarpium Citri Reticulatae 12, Pericarpium Citri Reticulatae Viride 13, Fructus Toosendan 16, Pinellia leaven 11, Fructus Crataegi 17, Massa Medicata Fermentata 16, Rhizoma Corydalis 14, Radix Glycyrrhizae 11.

4,, it is characterized in that described Radix Angelicae Sinensis is the Radix Angelicae Sinensis body that leaves out the beginning and the end according to the medicine of claim 1,2 or 3 described treatment cholecystitis.

5,, it is characterized in that the described Rhizoma Atractylodis Macrocephalae is the wild Rhizoma Atractylodis Macrocephalae according to the medicine of claim 1,2 or 3 described treatment cholecystitis.

6, according to the preparation method of the medicine of claim 1,2 or 3 described treatment cholecystitis, it is characterized in that:

(1), mixes, treats Radix Bupleuri, the Radix Paeoniae Alba, Rhizoma Cyperi, Pericarpium Citri Reticulatae Viride, Fructus Aurantii thoroughly vinegar immerse the back and fry dried with slow fire with vinegar respectively; (2), Radix Angelicae Sinensis, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Endothelium Corneum Gigeriae Galli, Massa Medicata Fermentata are fried to little yellow, Fructus Hordei Germinatus, Fructus Crataegi are fried to coke yellow with slow fire; (3), with Pinellia leaven with clear water soak, cool half-dried after, add clear water, Rhizoma Zingiberis Recens and Alumen and boil to interior no Bai Xinhou airing; (4), the Radix Aucklandiae is cleaned vexed section airing with clear water, several layers separately in Radix Aucklandiae sheet and toilet paper, as for stove room low baking temperature baking stewing, airing deoils; (5), with the above-mentioned drug powder that is mixed in proportion the cholecystitis that to obtain medical treatment through Chinese medicinal components and Rhizoma Chuanxiong, Cortex Magnoliae Officinalis, Radix Curcumae, Rhizoma Coptidis, Herba Lysimachiae, Poria, Pericarpium Citri Reticulatae, Fructus Toosendan, Rhizoma Corydalis, the pulverizing of Chinese medicine of licorice root component, the sterilization of the process of preparing Chinese medicine.