CN115989243A - 一种抗pd-l1/vegf融合蛋白 - Google Patents
一种抗pd-l1/vegf融合蛋白 Download PDFInfo
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- CN115989243A CN115989243A CN202180040147.1A CN202180040147A CN115989243A CN 115989243 A CN115989243 A CN 115989243A CN 202180040147 A CN202180040147 A CN 202180040147A CN 115989243 A CN115989243 A CN 115989243A
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Abstract
提供了抗PD‑L1/VEGF融合蛋白，其包含抗PD‑L1抗体、肽接头L和VEGFR1的D2结构域，其中VEGFR1的D2结构域的N末端通过肽接头L连接至抗PD‑L1抗体重链的C末端。本发明的融合蛋白具有治疗PD‑L1和VEGF活性相关的疾病的潜力。
Description
PCT国内申请，说明书已公开。
Claims (16)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010487517.3A CN113754776A (zh) | 2020-06-02 | 2020-06-02 | 一种抗pd-l1/vegf融合蛋白 |
| CN2020104875173 | 2020-06-02 | ||
| PCT/CN2021/096084 WO2021244371A1 (zh) | 2020-06-02 | 2021-05-26 | 一种抗pd-l1/vegf融合蛋白 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115989243A true CN115989243A (zh) | 2023-04-18 |
Family
ID=78782252
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010487517.3A Pending CN113754776A (zh) | 2020-06-02 | 2020-06-02 | 一种抗pd-l1/vegf融合蛋白 |
| CN202180040147.1A Pending CN115989243A (zh) | 2020-06-02 | 2021-05-26 | 一种抗pd-l1/vegf融合蛋白 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010487517.3A Pending CN113754776A (zh) | 2020-06-02 | 2020-06-02 | 一种抗pd-l1/vegf融合蛋白 |
Country Status (3)
| Country | Link |
|---|---|
| CN (2) | CN113754776A (zh) |
| TW (1) | TW202146447A (zh) |
| WO (1) | WO2021244371A1 (zh) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114685674B (zh) * | 2020-12-29 | 2023-09-29 | 瑞阳(苏州)生物科技有限公司 | 一种抗体融合蛋白及其应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109575140B (zh) * | 2017-09-29 | 2021-02-23 | 北京比洋生物技术有限公司 | 靶向pd-1或pd-l1且靶向vegf家族的双靶向融合蛋白及其用途 |
| KR102469248B1 (ko) * | 2018-02-28 | 2022-11-22 | 에이피 바이오사이언시스, 아이엔씨. | 표적치료법을 위한 체크포인트 억제력을 갖는 이중작용성 단백질 |
-
2020
- 2020-06-02 CN CN202010487517.3A patent/CN113754776A/zh active Pending
-
2021
- 2021-05-26 WO PCT/CN2021/096084 patent/WO2021244371A1/zh active Application Filing
- 2021-05-26 CN CN202180040147.1A patent/CN115989243A/zh active Pending
- 2021-06-02 TW TW110120074A patent/TW202146447A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW202146447A (zh) | 2021-12-16 |
| WO2021244371A1 (zh) | 2021-12-09 |
| CN113754776A (zh) | 2021-12-07 |
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