CN115957350A - 用于治疗家族性高胆固醇血症的基因疗法 - Google Patents

用于治疗家族性高胆固醇血症的基因疗法 Download PDF

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CN115957350A
CN115957350A CN202211286244.1A CN202211286244A CN115957350A CN 115957350 A CN115957350 A CN 115957350A CN 202211286244 A CN202211286244 A CN 202211286244A CN 115957350 A CN115957350 A CN 115957350A
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aav8
vector
raav
hldlr
tbg
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J.M.威尔逊
D.J.拉德
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University of Pennsylvania Penn
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University of Pennsylvania Penn
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CN202211286244.1A 2015-12-11 2016-12-09 用于治疗家族性高胆固醇血症的基因疗法 Pending CN115957350A (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201562266383P 2015-12-11 2015-12-11
US62/266383 2015-12-11
US201562269440P 2015-12-18 2015-12-18
US62/269440 2015-12-18
CN201680081580.9A CN109121421B (zh) 2015-12-11 2016-12-09 用于治疗家族性高胆固醇血症的基因疗法
PCT/US2016/065984 WO2017100682A1 (en) 2015-12-11 2016-12-09 Gene therapy for treating familial hypercholesterolemia

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US (2) US10889832B2 (https=)
EP (2) EP3400304B1 (https=)
JP (2) JP7328760B2 (https=)
KR (1) KR20180113990A (https=)
CN (2) CN115957350A (https=)
AU (2) AU2016366560A1 (https=)
BR (1) BR112018011687A2 (https=)
CA (1) CA3008142A1 (https=)
CO (1) CO2018007165A2 (https=)
ES (1) ES2921450T3 (https=)
IL (2) IL303850A (https=)
MA (1) MA43570A (https=)
MX (1) MX2018007080A (https=)
WO (1) WO2017100682A1 (https=)

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IL303850A (en) 2015-12-11 2023-08-01 Univ Pennsylvania Gene therapy for treating familial hypercholesterolemia
KR102695908B1 (ko) 2016-07-21 2024-08-14 스파크 테라퓨틱스, 인코포레이티드 재조합 아데노-관련 바이러스(rAAV) 벡터를 고수율로 생산하기 위한 확장 가능한 고회수 방법 및 이에 의해 생산된 재조합 아데노-관련 바이러스(rAAV) 벡터
WO2018022511A1 (en) 2016-07-25 2018-02-01 The Trustees Of The University Of Pennsylvania Compositions comprising a lecithin cholesterol acyltransferase variant and uses thereof
US11554147B2 (en) * 2017-02-20 2023-01-17 The Trustees Of The University Of Pennsylvania Gene therapy for treating familial hypercholesterolemia
KR20200104864A (ko) 2017-11-30 2020-09-04 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 뮤코다당류증 iiib형에 대한 유전자 요법
US20220040332A1 (en) * 2018-12-20 2022-02-10 The Trustees Of The University Of Pennsylvania Gene therapy for treating familial hypercholesterolemia
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WO2017100682A1 (en) 2017-06-15
CO2018007165A2 (es) 2018-07-19
AU2023201657A1 (en) 2023-06-15
EP3400304A1 (en) 2018-11-14
IL303850A (en) 2023-08-01
JP7328760B2 (ja) 2023-08-17
US20210285013A1 (en) 2021-09-16
IL259850B2 (en) 2023-11-01
CN109121421A (zh) 2019-01-01
CA3008142A1 (en) 2017-06-15
IL259850A (en) 2018-07-31
KR20180113990A (ko) 2018-10-17
MA43570A (fr) 2018-11-14
JP2022050575A (ja) 2022-03-30
EP3400304B1 (en) 2022-04-06
BR112018011687A2 (pt) 2018-12-04
JP2019504003A (ja) 2019-02-14
US20190002917A1 (en) 2019-01-03
ES2921450T3 (es) 2022-08-25
US10889832B2 (en) 2021-01-12
MX2018007080A (es) 2018-11-12
AU2016366560A1 (en) 2018-06-28
CN109121421B (zh) 2022-11-01
EP4085934A1 (en) 2022-11-09

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