CN115944682A - Traditional Chinese medicine navel paste for treating male prostate diseases and preparation method - Google Patents
Traditional Chinese medicine navel paste for treating male prostate diseases and preparation method Download PDFInfo
- Publication number
- CN115944682A CN115944682A CN202211687159.6A CN202211687159A CN115944682A CN 115944682 A CN115944682 A CN 115944682A CN 202211687159 A CN202211687159 A CN 202211687159A CN 115944682 A CN115944682 A CN 115944682A
- Authority
- CN
- China
- Prior art keywords
- parts
- chinese medicine
- traditional chinese
- navel
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 86
- 208000017497 prostate disease Diseases 0.000 title claims abstract description 26
- 238000002360 preparation method Methods 0.000 title claims abstract description 16
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims abstract description 17
- 239000011505 plaster Substances 0.000 claims abstract description 17
- 235000017803 cinnamon Nutrition 0.000 claims abstract description 15
- 229910052717 sulfur Inorganic materials 0.000 claims abstract description 15
- 239000011593 sulfur Substances 0.000 claims abstract description 15
- 241000402754 Erythranthe moschata Species 0.000 claims abstract description 14
- 210000000582 semen Anatomy 0.000 claims abstract description 11
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 9
- AXTGDCSMTYGJND-UHFFFAOYSA-N 1-dodecylazepan-2-one Chemical compound CCCCCCCCCCCCN1CCCCCC1=O AXTGDCSMTYGJND-UHFFFAOYSA-N 0.000 claims abstract description 9
- 241000173529 Aconitum napellus Species 0.000 claims abstract description 9
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims abstract description 9
- 239000004615 ingredient Substances 0.000 claims abstract description 8
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims abstract description 7
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims abstract description 7
- 229940116229 borneol Drugs 0.000 claims abstract description 7
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims abstract description 7
- 239000010630 cinnamon oil Substances 0.000 claims abstract description 7
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims abstract description 7
- 229940041616 menthol Drugs 0.000 claims abstract description 7
- 244000223760 Cinnamomum zeylanicum Species 0.000 claims description 14
- 238000003756 stirring Methods 0.000 claims description 10
- 239000000853 adhesive Substances 0.000 claims description 9
- 239000011812 mixed powder Substances 0.000 claims description 8
- 229940023019 aconite Drugs 0.000 claims description 7
- 238000000227 grinding Methods 0.000 claims description 7
- 239000000843 powder Substances 0.000 claims description 7
- 235000013399 edible fruits Nutrition 0.000 claims description 6
- 239000011259 mixed solution Substances 0.000 claims description 6
- 235000018645 Allium odorum Nutrition 0.000 claims description 5
- 235000005338 Allium tuberosum Nutrition 0.000 claims description 5
- 239000004831 Hot glue Substances 0.000 claims description 5
- 230000001070 adhesive effect Effects 0.000 claims description 5
- 239000004568 cement Substances 0.000 claims description 5
- 239000011248 coating agent Substances 0.000 claims description 5
- 238000000576 coating method Methods 0.000 claims description 5
- 238000010438 heat treatment Methods 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 5
- 241000212948 Cnidium Species 0.000 claims description 4
- 229920000715 Mucilage Polymers 0.000 claims description 4
- 238000002844 melting Methods 0.000 claims description 4
- 230000008018 melting Effects 0.000 claims description 4
- 238000004537 pulping Methods 0.000 claims description 4
- 239000007788 liquid Substances 0.000 claims description 3
- 244000003377 Allium tuberosum Species 0.000 claims description 2
- 238000010792 warming Methods 0.000 abstract description 26
- 230000000694 effects Effects 0.000 abstract description 22
- 229940079593 drug Drugs 0.000 abstract description 20
- 238000000034 method Methods 0.000 abstract description 7
- 230000008569 process Effects 0.000 abstract description 2
- 241000723347 Cinnamomum Species 0.000 abstract 1
- 210000003734 kidney Anatomy 0.000 description 38
- 201000010099 disease Diseases 0.000 description 10
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 10
- 235000016639 Syzygium aromaticum Nutrition 0.000 description 9
- 244000223014 Syzygium aromaticum Species 0.000 description 8
- 241000227129 Aconitum Species 0.000 description 7
- 201000007094 prostatitis Diseases 0.000 description 7
- 206010067484 Adverse reaction Diseases 0.000 description 6
- 240000002234 Allium sativum Species 0.000 description 6
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 description 6
- 206010060862 Prostate cancer Diseases 0.000 description 6
- 208000004403 Prostatic Hyperplasia Diseases 0.000 description 6
- 208000000236 Prostatic Neoplasms Diseases 0.000 description 6
- 230000006838 adverse reaction Effects 0.000 description 6
- 235000004611 garlic Nutrition 0.000 description 6
- 208000026455 prostate symptom Diseases 0.000 description 6
- 210000000952 spleen Anatomy 0.000 description 6
- 210000001113 umbilicus Anatomy 0.000 description 6
- 125000003118 aryl group Chemical group 0.000 description 5
- 230000027939 micturition Effects 0.000 description 5
- 238000002203 pretreatment Methods 0.000 description 5
- 239000008159 sesame oil Substances 0.000 description 5
- 235000011803 sesame oil Nutrition 0.000 description 5
- 210000002784 stomach Anatomy 0.000 description 5
- 244000089698 Zanthoxylum simulans Species 0.000 description 4
- 210000001835 viscera Anatomy 0.000 description 4
- 244000000383 Allium odorum Species 0.000 description 3
- 241000721047 Danaus plexippus Species 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 230000004087 circulation Effects 0.000 description 3
- 230000007812 deficiency Effects 0.000 description 3
- 238000009826 distribution Methods 0.000 description 3
- 201000001881 impotence Diseases 0.000 description 3
- 210000004185 liver Anatomy 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 239000006187 pill Substances 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 208000010228 Erectile Dysfunction Diseases 0.000 description 2
- 241001676573 Minium Species 0.000 description 2
- 239000005864 Sulphur Substances 0.000 description 2
- 235000009932 Zanthoxylum simulans Nutrition 0.000 description 2
- 230000002411 adverse Effects 0.000 description 2
- 230000007012 clinical effect Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 239000000796 flavoring agent Substances 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- 239000003205 fragrance Substances 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 230000001976 improved effect Effects 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 239000002674 ointment Substances 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 208000017520 skin disease Diseases 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000007619 statistical method Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 208000011580 syndromic disease Diseases 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 210000002700 urine Anatomy 0.000 description 2
- JHGWQSGWUPCKNT-UHFFFAOYSA-N 2-tert-butyl-4-methyl-1,3,5-trinitrobenzene Chemical compound CC1=C([N+]([O-])=O)C=C([N+]([O-])=O)C(C(C)(C)C)=C1[N+]([O-])=O JHGWQSGWUPCKNT-UHFFFAOYSA-N 0.000 description 1
- 241001164374 Calyx Species 0.000 description 1
- 244000037364 Cinnamomum aromaticum Species 0.000 description 1
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 description 1
- 235000011511 Diospyros Nutrition 0.000 description 1
- 244000236655 Diospyros kaki Species 0.000 description 1
- 206010013654 Drug abuse Diseases 0.000 description 1
- 208000030453 Drug-Related Side Effects and Adverse reaction Diseases 0.000 description 1
- 244000061408 Eugenia caryophyllata Species 0.000 description 1
- 241000628997 Flos Species 0.000 description 1
- 238000001135 Friedman test Methods 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- 244000153234 Hibiscus abelmoschus Species 0.000 description 1
- 206010024419 Libido decreased Diseases 0.000 description 1
- 238000000585 Mann–Whitney U test Methods 0.000 description 1
- 240000002853 Nelumbo nucifera Species 0.000 description 1
- 235000006508 Nelumbo nucifera Nutrition 0.000 description 1
- 235000006510 Nelumbo pentapetala Nutrition 0.000 description 1
- 240000005373 Panax quinquefolius Species 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 206010035664 Pneumonia Diseases 0.000 description 1
- 206010036018 Pollakiuria Diseases 0.000 description 1
- 206010038967 Retrograde ejaculation Diseases 0.000 description 1
- 206010041497 Spermatorrhoea Diseases 0.000 description 1
- 206010070863 Toxicity to various agents Diseases 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 208000013507 chronic prostatitis Diseases 0.000 description 1
- 230000019771 cognition Effects 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000009429 distress Effects 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 238000003255 drug test Methods 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 238000010832 independent-sample T-test Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000002398 materia medica Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000009112 niuhuang Substances 0.000 description 1
- 238000001422 normality test Methods 0.000 description 1
- -1 oleum Cinnamomi Chemical compound 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 229940126532 prescription medicine Drugs 0.000 description 1
- 210000002307 prostate Anatomy 0.000 description 1
- 208000020016 psychiatric disease Diseases 0.000 description 1
- 230000005180 public health Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 208000011117 substance-related disease Diseases 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 210000003954 umbilical cord Anatomy 0.000 description 1
- 210000004916 vomit Anatomy 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a traditional Chinese medicine navel paste for treating male prostate diseases and a preparation method thereof, wherein the traditional Chinese medicine navel paste comprises a traditional Chinese medicine formula and ingredients, and the traditional Chinese medicine formula comprises the following components in parts by weight: 10-15 parts of semen allii tuberosi, 10-15 parts of fructus cnidii, 10-15 parts of black monkshood, 10-15 parts of cinnamon, 30-40 parts of pericarpium zanthoxyli, 10-15 parts of sulfur, 1-3 parts of fructus caryophylli and 3-6 parts of musk. The ingredients comprise azone, menthol, borneol and cinnamon oil. The preparation formula is based on the essence-securing kidney-tonifying navel-warming plaster derived from the traditional Chinese medicine classic ancient book mysterious section, and through years of clinical practice and observation of curative effects, the essence is refined into 8 medicines to prepare the essence-securing kidney-tonifying navel-warming plaster, and the formula is rigorous and the medicines are simple and effective. By adopting a professional modern pharmaceutical scheme and combining a modern pharmaceutical process on the basis of keeping the traditional Chinese medicine patch, the preparation scheme can ensure stable curative effect and good safety.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicine navel patches, in particular to a traditional Chinese medicine navel patch for treating male prostate diseases and a preparation method thereof.
Background
The prostate diseases comprise common male diseases such as prostatic hyperplasia, prostatitis, prostate cancer and the like, the traditional Chinese medicine is widely applied to clinical treatment as an important treatment mode for treating the prostate diseases at present, and the traditional Chinese medicine has unique treatment advantages and is complementary with western medicine treatment to improve the curative effect. The navel patch in the traditional Chinese medicine external treatment method is one of representative treatment methods, the clinical application of the traditional Chinese medicine navel patch in the modern medicine is very wide, and the clinical effect of the traditional Chinese medicine navel patch on improving allergic rhinoinflammation is good by researching Wen Qitie by relevant scholars in the Guangdong region; researchers related to Anhui region study that the traditional Chinese medicine navel paste has good clinical curative effect on treating infantile pneumonia by external application.
Prostate diseases are one of the male diseases which are mainly researched in modern medicine, the life quality of patients is seriously influenced, the burden of national public health care is increased, the curative effect of the current medical treatment means is limited, and due to the difference of the cognition of the theory of the traditional Chinese medicine, the traditional Chinese medicine navel paste for treating prostate diseases has a long history but lacks a unified treatment standard, so that the medicinal composition and the use of the navel paste have great difference, and certain difference exists in clinical popularization and curative effect. The navel paste attaches importance to the experience of forebody in the theory of traditional Chinese medicine, selects the essence-securing, kidney-tonifying and navel-warming paste in the classic ancient book of traditional Chinese medicine, namely 'Kaisheng Mi Pou', as the basis under the guidance of professor Tan Xinhua of famous and old traditional Chinese medicine, adopts the traditional and modern combined pharmaceutical technology in the pharmaceutical scheme, and improves the curative effect and the medication safety of the navel paste.
Summary of the invention
Aiming at the problems in the prior art, the invention aims to provide a traditional Chinese medicine navel paste for treating male prostate diseases and a preparation method thereof, which can realize the function of relieving and treating the prostate diseases of patients.
In order to solve the problems, the invention adopts the following technical scheme:
a traditional Chinese medicine navel paste for treating male prostate diseases comprises a traditional Chinese medicine formula and ingredients, wherein the traditional Chinese medicine formula comprises the following components in parts by weight: 10-15 parts of semen allii tuberosi, 10-15 parts of fructus cnidii, 10-15 parts of black monkshood, 10-15 parts of cinnamon, 30-40 parts of pericarpium zanthoxyli, 10-15 parts of sulfur, 1-3 parts of fructus caryophylli and 3-6 parts of musk.
Preferably, the ingredients consist of azone, menthol, borneol and cinnamon oil.
A preparation method of a traditional Chinese medicine navel paste for treating male prostate diseases comprises the following steps:
s1, grinding, namely grinding and crushing seven kinds of Chinese chives, namely 10-15 parts by weight of semen allii tuberosi, 10-15 parts by weight of fructus cnidii, 10-15 parts by weight of black monkshood, 10-15 parts by weight of cinnamon, 30-40 parts by weight of pericarpium zanthoxyli, 10-15 parts by weight of sulfur and 1-3 parts by weight of fructus caryophylli into fine powder, and uniformly mixing to obtain mixed powder for later use;
s2, preparing materials, namely uniformly stirring a proper amount of azone, menthol, borneol and cinnamon oil to obtain a mixed solution for later use;
s3, pulping, namely heating and melting hot melt adhesive, slowly adding the mixed powder obtained in the step S1, the mixed liquid obtained in the step S2 and 3-6 parts of musk, and uniformly stirring to prepare adhesive cement;
and S4, preparing the navel plaster, namely uniformly coating the mucilage obtained in the step S3 on the plaster, covering a lining, and slicing to obtain the finished navel plaster.
Compared with the prior art, the invention has the advantages that:
1. the navel paste is prepared by selecting the essence-securing kidney-tonifying navel-warming paste from classic ancient book of traditional Chinese medicine < she sheng Mi Pou > as a basis, and through years of clinical practice and observation of curative effect, 8 medicines are refined to prepare the essence-securing kidney-tonifying navel paste, and the formula is rigorous, and the medicines are simple and effective.
2. The preparation process adopts a professional modern preparation scheme, and the preparation scheme can ensure stable curative effect and good safety by combining the modern preparation process on the basis of keeping the traditional Chinese medicine patch.
Relevant researchers self-prepare a traditional Chinese medicine navel paste for treating chronic prostatitis, the traditional Chinese medicine navel paste is good in curative effect evaluation, the traditional Chinese medicine navel paste is adopted in the manufacturing process, the traditional Chinese medicine composition is mainly the medicine for promoting qi circulation with pungent and warm natured drugs in the view of the traditional Chinese medicine theory, and research results show that the traditional Chinese medicine navel paste is good in clinical curative effect and safety in the aspect of treating prostate diseases, so that the scheme has scientificity and feasibility;
the original text carrying "Fu essence" means the true water in the kidney, which depends on the true fire to nourish the kidney. This fire is peculiar to the kidney, travels through the triple energizer, enters the nail and gallbladder, and plays a role in the heaven and monarch, so Wen Baihai, unblocks the seven orifices, nourishes the essence of the five zang-organs and six fu-organs, and is also stored in the kidney. Is also a fire, the father of all things, so it is recorded as: monarch and imperial fire are not enough to generate all things; people who are not so hot cannot live. If the fire is weakened, there will be no generation of any substance ", it is thought that the transformation of the kidney yang into fire can nourish the five zang-organs and six fu-organs, and generate all the substances, emphasizing the important meaning of kidney yang in the normal physiological activities of the human body, while insufficiency of kidney yang can lead to the prostate related diseases such as" man is turbid white and spermatorrhea "as mentioned above. The original text "paste" is warm and warm, and it is used to stick on the umbilicus, and has a miraculous effect. What is the person who is attached to the umbilicus? The cap is shaped like the end of the sexual organ of the male and female, and forms a river channel, and a stem is penetrated in the middle, such as the lotus pistil which is the umbilical cord. When there is a fire in the core, the door is hit. This point is located between the two kidneys, and is left and right open and closed. Just like the house account, it is named as umbilicus. If the umbilicus is the root of Mingmen, it is warm to help its primordial yang and strengthen its true fire, and benefit the origin of this kidney, then the kidney can store essence without leakage, explaining that the umbilicus patch is usually made of warm drugs, and further explaining that the umbilicus is located at the key pivot position of Mingmen kidney fire, and the drugs for warming and invigorating kidney yang are applied at this position to help the potency of the drug to directly reach the deficiency viscera, which is the root cause of kidney warming and invigorating by navel-applying therapy.
The prescription of the ointment for securing essence, tonifying kidney and warming navel comprises the following components of one or two Chinese chives seeds, one or two common cnidium fruits, one or two giant aconites roots, one or two cassia barks, three or two Sichuan pepper fruits, two jin of true sesame oil, twelve men for smooth lead and clean, one or two Shikuo sulphur, one jin of female clove and three jin of musk, which are ground respectively, and one single garlic is prepared, wherein the dosages of each component are respectively 10-15 parts by weight of Chinese chives seeds, 10-15 parts by weight of common cnidium fruits, 10-15 parts by weight of black aconite, 10-15 parts by weight of cinnamon, 30-40 parts by weight of Sichuan pepper fruits, 10-15 parts by weight of sulphur, 1-3 parts by weight of female clove and 3-6 parts by weight of musk, and sesame oil and single garlic which have drug toxicity and influence on the pharmaceutical technology are screened.
The detailed preparation method of the ointment is recorded in the original text, so that the preparation method is combined with the advanced process of modern pharmacy on the basis of following the initial preparation method as much as possible, and aims to ensure stable drug effect, and the rest 7 medicines except the artificial musk are crushed into fine powder and uniformly mixed for later use; mixing azone, mentholum, borneolum Syntheticum, and oleum Cinnamomi, and stirring; heating hot melt adhesive, slowly adding the above 7 medicinal materials fine powder and mixed solution of Mentholum, borneolum Syntheticum, oleum Cinnamomi, and azone, stirring to obtain adhesive cement, coating paste, covering with liner, and slicing.
The essence-securing kidney-tonifying navel-warming plaster analyzed from the composition of the prescription is mainly divided into two types of medicines for warming and invigorating kidney yang and aromatic, pungent and warm. The medicines for warming and invigorating kidney yang comprise monkshood, cinnamon, sulfur and fructus cnidii, wherein the monkshood and the cinnamon are matched with each other by a classical medicine pair and have the effect of warming and invigorating kidney yang, and typical medicines comprise Jinkui kidney qi pills and Fugui middle-jiao pills. The sulfur and the fructus cnidii are commonly used external treatment medicines in the traditional Chinese medicine, the medicine properties are warm and warm, the skin diseases can be treated, the medicine effect is clear, safe and stable, the sulfur has sour and warm taste and enters kidney and large intestine channels, the internal administration can tonify fire and strengthen yang, and the warm and warm medicine properties can also be used for treating yin syndrome skin diseases such as dorsal furuncle and malignant boil. The fructus cnidii has pungent, bitter and warm natures, enters kidney meridian, has the effects of warming kidney and tonifying yang, is used for warming and resolving women's yin cold in the fructus cnidii powder in the golden kui Yao L ü e, and is used for treating impotence by using the fructus cnidii pill in the Qian jin Yao Fang, so that the four medicines of the monkshood, the cinnamon, the sulfur and the fructus cnidii are used together to play the effects of warming and tonifying kidney yang.
The aromatic and pungent herbs include semen Allii Tuberosi, fructus Zanthoxyli, flos Caryophylli, moschus, and Bulbus Allii. The semen allii tuberosi is pungent, sweet and warm in flavor, enters liver and kidney meridians, and has the effects of warming and nourishing liver and kidney, tonifying yang and securing essence. The zanthoxylum bungeanum and the single garlic are representative medicines with homology of medicine and food, have pungent and warm properties, enter spleen and stomach channels, and can tonify spleen and stomach by warming and invigorating middle-jiao, and the acquired spleen yang and foot can tonify the acquired kidney yang, and the zanthoxylum bungeanum has the function of warming and invigorating kidney yang by entering right kidney and tonifying fire. Clove is fragrant in medicine taste, clove can emit various fragrances when the spleen and stomach are warmed in Kaibao, clove is warm in medicine property, and fragrance can promote qi circulation to eliminate dampness and warm and nourish the spleen and stomach, so that deficiency and vomit of children can be treated as in Ben Cao gang mu, and clove and persimmon calyx decoction, which are typical prescription medicines in Shang Han pestilence tiao Bian Tang in later generations, take clove as monarch medicine to warm the stomach and reduce the adverse flow of qi. This herb Jing Shu (fundamental and sparse theory of materia Medica) is contraindicated for all syndromes with fire-heat. It is not due to deficiency-cold, so it is not used in any way to further clarify clove as a warm-heat product. Musk, pungent in flavor and warm in property, enters heart and spleen meridians, and is commonly used for inducing resuscitation and refreshing mind due to its aromatic smell, such as Angong Niuhuang Wan and Zhibao Dan. Therefore, the reason for analyzing the navel paste agent using aromatic pungent-warm drugs is that the effect of warming and invigorating kidney yang is further enhanced on one hand, and on the other hand, the effect of warming and invigorating kidney yang is exerted on the navel part through aromatic drugs, which is equivalent to the effect of applying the drugs on the kidney for resuscitation, and acts on kidney fire on the kidney through the way of orifice, and kidney yang and sufficient kidney yang are further transmitted to internal organs and are distributed on the whole body through the circulation of blood vessels, so that the pathological state of yang-qi deficiency of five viscera and six viscera is corrected. Treating prostate diseases caused by insufficiency of kidney-yang.
The navel paste is optimized on the basis of selecting the essence-securing, kidney-tonifying and navel-warming paste in the classic ancient Chinese medical book 'Kangsheng Mi Po' under the guidance of the professor Tan Xinhua of famous old Chinese medicine by referring to the Chinese medicine treatment guidelines of common male diseases such as prostatic hyperplasia, prostatitis and prostatic cancer, and the like, wherein 8 medicines are selected as the formula, so that the navel paste has the effects of warming and invigorating kidney yang, promoting qi and activating blood circulation, and meets the requirements of the Chinese medicine treatment method of the prostate diseases.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention. It is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments, and all other embodiments obtained by those skilled in the art without any inventive work are within the scope of the present invention.
In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "top/bottom", etc., indicate orientations or positional relationships based on the orientation or positional relationships for convenience in describing the present invention and simplifying the description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed in a specific orientation, and be operated, and thus should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "disposed," "sleeved/connected," "connected," and the like are to be construed broadly, e.g., "connected," which may be fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
The first embodiment is as follows:
a traditional Chinese medicine navel paste for treating male prostate diseases comprises a traditional Chinese medicine formula and ingredients, wherein the traditional Chinese medicine formula comprises the following components in parts by weight: 15 parts of semen allii tuberosi, 15 parts of fructus cnidii, 10 parts of black aconite, 10 parts of cinnamon, 30 parts of pericarpium zanthoxyli, 15 parts of sulfur, 1 part of fructus caryophylli and 4 parts of musk;
a traditional Chinese medicine navel paste for treating male prostate diseases comprises the following steps: step S1, grinding, namely grinding and crushing seven kinds of Chinese chive seeds 15 parts by weight, common cnidium fruit 15 parts by weight, black aconite 10 parts by weight, cinnamon 10 parts by weight, pericarpium zanthoxyli 30 parts by weight, sulfur 15 parts by weight and clove 1 part by weight into fine powder, and uniformly mixing to obtain mixed powder for later use; s2, preparing materials, namely uniformly stirring a proper amount of azone, menthol, borneol and cinnamon oil to obtain a mixed solution for later use; s3, pulping, namely heating and melting hot melt adhesive, slowly adding the mixed powder obtained in the step S1, the mixed solution obtained in the step S2 and 4 parts of musk, and uniformly stirring to prepare adhesive cement; and S4, preparing the navel plaster, namely uniformly coating the mucilage obtained in the step S3 on the plaster, covering a lining, and slicing to obtain the finished navel plaster.
Example two:
a traditional Chinese medicine navel paste for treating male prostate diseases comprises a traditional Chinese medicine formula and ingredients, wherein the traditional Chinese medicine formula comprises the following components in parts by weight: 11 parts of semen allii tuberosi, 12 parts of fructus cnidii, 10 parts of black aconite, 10 parts of cinnamon, 30 parts of pericarpium zanthoxyli, 15 parts of sulfur, 1 part of fructus caryophylli, 4 parts of musk, 1 part of minium, 1 part of garlic and 5 parts of sesame oil;
a traditional Chinese medicine navel paste for treating male prostate diseases comprises the following steps: s1, grinding 11 parts of semen allii tuberosi, 12 parts of fructus cnidii, 10 parts of black aconite, 10 parts of cinnamon, 30 parts of pericarpium zanthoxyli, 15 parts of sulfur and 1 part of fructus caryophylli into fine powder, and uniformly mixing to obtain mixed powder for later use; s2, preparing materials, namely uniformly stirring a proper amount of azone, menthol, borneol and cinnamon oil to obtain a mixed solution for later use; s3, pulping, namely heating and melting hot melt adhesive, slowly adding the mixed powder obtained in the step S1, the mixed liquid obtained in the step S2, 4 parts of musk, 1 part of red lead, 1 part of single garlic and 5 parts of sesame oil, and uniformly stirring to prepare adhesive cement; and S4, preparing the navel plaster, namely uniformly coating the mucilage obtained in the step S3 on the plaster, covering a lining, and slicing to obtain the finished navel plaster.
The navel patches prepared in the first and second embodiments were tested, and the procedure was as follows: the prostate disease patients were divided into 2 groups (randomized by computer generated random numbers) according to the complete randomization principle, and the differences were not statistically significant (P > 0.05) when compared to the baseline in each group of 20 and 2 groups, see table 1.
TABLE 1 comparison of baseline data for two groups of pre-treatment patients (min, x + -s)
1.1.1 inclusion criteria
(1) The male patients who are actively treated for the prostate diseases comprise three diseases of prostatitis, prostatic hyperplasia and prostate cancer; (2) The Western medicine standard refers to the standard guide for diagnosis of prostatitis, prostatic hyperplasia and prostatic cancer; (3) male patients aged 20-80 years; and (4) patients know the information and have good compliance.
1.1.2 exclusion criteria
(1) Acute and chronic urogenital infections; (2) Patients suffering from a psychiatric disorder in need of treatment or undergoing treatment; (3) those who have a history of drug abuse within 2 years; (4) Common male diseases such as Erectile Dysfunction (ED), retrograde ejaculation, hyposexuality and the like exist; (5) taking part in other treatment drug tests within nearly 3 months; (6) Diseases of the whole body system such as diseases of the heart and brain system, diseases of the liver and kidney system and the like or other related organic pathological changes; (7) receiving operation such as circumcision and the like during treatment; (8) Those who do not take the medicine as required, withdraw from the way, lose contact and lose visitors.
1.2 methods
The control group is administered with conventional treatment scheme and original formula of navel warming patch for arresting spontaneous emission, invigorating kidney, and warming navel according to prostatitis, prostatic hyperplasia, and prostatic cancer, one patch for each time, 2 times daily, and 8 weeks continuously.
The prescription consists of the following components: 10-15 parts of semen allii tuberosi, 10-15 parts of fructus cnidii, 10-15 parts of black monkshood, 10-15 parts of cinnamon, 30-40 parts of pericarpium zanthoxyli, 10-15 parts of sulfur, 1-3 parts of fructus caryophylli, 3-6 parts of musk, 1 part of minium, 1 part of garlic and 5 parts of sesame oil.
The test group respectively gives a conventional treatment scheme and a navel warming patch for securing essence, tonifying the kidney and warming the navel according to three diseases of prostatitis, prostatic hyperplasia and prostatic cancer, and the navel patch is externally applied, one patch is used every time, 2 times a day and is continuously used for 8 weeks.
The prescription consists of the following components: 10-15 parts of semen allii tuberosi, 10-15 parts of fructus cnidii, 10-15 parts of black monkshood, 10-15 parts of cinnamon, 30-40 parts of pericarpium zanthoxyli, 10-15 parts of sulfur, 1-3 parts of fructus caryophylli and 3-6 parts of musk.
1.3 Observation index
1.3.1 International Prostate Symptom Score (IPSS)
The scoring scale comprises 7 indexes of whether the time interval between two times of urination is always shorter than 2h, whether there is intermittent urination, whether there is urination waiting phenomenon, whether there is always urine endless feeling, whether there is urine line thinning phenomenon, whether it needs to exert force to urinate, and the urination frequency of getting up to bed before sleeping in the morning, wherein the total score is the sum of all scores, 0-7 is mild, 8-19 is moderate, and 20-35 is severe.
1.3.2 quality of life score (QOL)
For assessing the patient's satisfaction with the current quality of life, the evaluation criteria are: the happiness is 0 point, the satisfaction is 1 point, the basic satisfaction is 2 points, the 3 points can be calculated, the unsatisfactory 4 points, the distress is 5 points, the bad 6 points, the lower the score is, the better the life quality is.
1.3.3 adverse reactions
Adverse reactions during treatment were observed and the probability and type of adverse events occurring during treatment were recorded.
1.4 statistical analysis
The collected clinical data is input in Excel, statistical analysis is carried out on the data by using SPSS26.0 software, the measured data is firstly subjected to normality test, when the measured data accords with normal distribution, an independent sample T test is adopted for comparison among groups, repeated variance measurement is adopted for comparison in the groups, and the result is expressed by (x +/-s). Nonparametric tests are adopted when the distribution is not in accordance with normal distribution, mann-Whitney U test is adopted for comparison among groups, friedman test is adopted for comparison in groups, and results are described. Differences were considered statistically significant with P <0.05.
2 results
2.1 International prostate symptom score in two groups of patients
Compared with the international prostate symptom scores of the patients in the pre-treatment 2 groups, the difference is not statistically significant (P is more than 0.05), and the results are comparable. In the group comparison, there was a significant increase in the international prostate symptom score before treatment and after treatment (P < 0.05) in both groups of patients compared to before treatment. In the comparison between groups, the improvement was more significant in the patch group compared to the control group (P < 0.05). See table 2.
TABLE 2 comparison of International Prostate Symptom Scores (IPSS) of two groups of patients before and after treatment (points, x + -s)
| Group of | n | Before treatment | After treatment |
| Navel plaster set | 20 | 20.55±3.38 | 8.95±2.70* |
| Control group | 20 | 22.30±2.32 | 10.90±2.67 |
Note: p <0.01 compared to control group.
2.2 quality of Life score
Compared with the quality of life scores of the patients in the pre-treatment 2 groups, the difference is not statistically significant (P is more than 0.05), and the results are comparable. In the group comparison, both groups of patients had a significant increase in the pre-treatment and post-treatment quality of life scores compared to the pre-treatment (P < 0.05). In the comparison between groups, the improvement was more significant in the patch group compared to the control group (P < 0.05). See table 3.
TABLE 3 comparison of quality of life scores before and after treatment (score, x + -s)
Note: p <0.05 compared to control group.
2.3 adverse reactions in two groups of patients
During treatment, the navel plaster group and the control group have adverse reaction events, and the adverse reaction rate of the 2 groups is not obvious in difference and has no statistical significance (P is more than 0.05).
The research result shows that after two groups of patients are treated, the urination symptoms of the patients can be improved, the international prostate symptom scores of the patients with prostate diseases are reduced, and according to the reduction of the life quality scores, the subjective symptoms of the patients are improved, the umbilical paste group has statistical significance compared with a control group in terms of curative effect difference, the two groups of patients do not have statistical difference in terms of adverse reactions, and the medicine safety is good. In conclusion, the essence-securing kidney-tonifying navel-warming patch has a remarkable clinical effect on treating the patients with the prostate diseases, can effectively improve the urination symptoms and the life quality of the patients, shows higher safety and has a certain application prospect.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to cover the technical scope of the present invention, the technical solutions and the modifications thereof according to the present invention within the technical scope of the present invention.
Claims (3)
1. A traditional Chinese medicine navel paste for treating male prostate diseases comprises a traditional Chinese medicine formula and ingredients, and is characterized in that the traditional Chinese medicine formula consists of the following components in parts by weight: 10-15 parts of semen allii tuberosi, 10-15 parts of fructus cnidii, 10-15 parts of black aconite, 10-15 parts of cinnamon, 30-40 parts of pericarpium zanthoxyli, 10-15 parts of sulfur, 1-3 parts of fructus caryophylli and 3-6 parts of musk.
2. A traditional Chinese medicine navel paste for treating male prostate diseases is characterized in that ingredients comprise azone, menthol, borneol and cinnamon oil.
3. A preparation method of a traditional Chinese medicine navel paste for treating male prostate diseases is characterized by comprising the following steps:
step S1, grinding, namely grinding and crushing seven kinds of Chinese chive seeds 10-15 parts by weight, common cnidium fruit 10-15 parts by weight, black aconite pieces 10-15 parts by weight, cinnamon 10-15 parts by weight, pericarpium zanthoxyli 30-40 parts by weight, sulfur 10-15 parts by weight and fructus syringae 1-3 parts by weight into fine powder, and uniformly mixing to obtain mixed powder for later use;
s2, preparing materials, namely uniformly stirring a proper amount of azone, menthol, borneol and cinnamon oil to obtain a mixed solution for later use;
s3, pulping, namely heating and melting hot melt adhesive, slowly adding the mixed powder obtained in the step S1, the mixed liquid obtained in the step S2 and 3-6 parts of musk, and uniformly stirring to prepare adhesive cement;
and S4, preparing the navel plaster, namely uniformly coating the mucilage obtained in the step S3 on the plaster, covering a lining, and slicing to obtain the finished navel plaster.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211687159.6A CN115944682A (en) | 2022-12-27 | 2022-12-27 | Traditional Chinese medicine navel paste for treating male prostate diseases and preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211687159.6A CN115944682A (en) | 2022-12-27 | 2022-12-27 | Traditional Chinese medicine navel paste for treating male prostate diseases and preparation method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115944682A true CN115944682A (en) | 2023-04-11 |
Family
ID=87281968
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211687159.6A Pending CN115944682A (en) | 2022-12-27 | 2022-12-27 | Traditional Chinese medicine navel paste for treating male prostate diseases and preparation method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115944682A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1212160A (en) * | 1997-11-05 | 1999-03-31 | 宋兆普 | Baoyuan Fuchun Yunqi plaster |
| CN101053641A (en) * | 2007-05-18 | 2007-10-17 | 宋兆普 | Baoyuan kidney-invigorating navel plaster |
| CN102973866A (en) * | 2012-11-26 | 2013-03-20 | 姜莉蔚 | Chinese traditional medicine compound navel patch for treating prostate disease |
-
2022
- 2022-12-27 CN CN202211687159.6A patent/CN115944682A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1212160A (en) * | 1997-11-05 | 1999-03-31 | 宋兆普 | Baoyuan Fuchun Yunqi plaster |
| CN101053641A (en) * | 2007-05-18 | 2007-10-17 | 宋兆普 | Baoyuan kidney-invigorating navel plaster |
| CN102973866A (en) * | 2012-11-26 | 2013-03-20 | 姜莉蔚 | Chinese traditional medicine compound navel patch for treating prostate disease |
Non-Patent Citations (1)
| Title |
|---|
| 王国斌, 张力, 宋兆普, 李素莲: "保元复春磁药贴治疗前列腺增生症临床研究", 中医研究, vol. 2013, no. 05, pages 155 - 156 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101444611B (en) | Traditional Chinese medicine composition for treating lumbocrural pain and lumbar intervertebral disc protrusion and preparation method thereof | |
| CN100579556C (en) | Preparation method of Chinese medicinal capsule for treating apoplexy | |
| CN102755614B (en) | Multi-effect acupuncture point application ointment and preparation method | |
| JP7356156B2 (en) | Method for preparing Chinese herbal medicine using calcium-based ion solution | |
| CN115944682A (en) | Traditional Chinese medicine navel paste for treating male prostate diseases and preparation method | |
| Liu | Traditional Chinese Medicine for Visceral Pain | |
| Ligaa et al. | Medicinal plants of Mongolia and their use in traditional medicine | |
| CN105343675A (en) | Traditional Chinese medicine preparation for treating adiposis and preparation method thereof | |
| CN105497262A (en) | Medicine composition for treating liver-yin and kidney-yin deficiency type polycystic ovarian syndrome | |
| CN105641330A (en) | Traditional Chinese medicine composition for invigorating kidney and strengthening yang | |
| CN104352973A (en) | Chinese patent medicine for postpartum depression | |
| CN104815111A (en) | Traditional Chinese medicine composition for treating lumbar disc herniation, cervical spondylosi and osteoproliferation | |
| CN116999486B (en) | Zhuang medicine compound medicine for treating ischemic stroke convalescence and preparation method thereof | |
| CN113855778B (en) | Traditional Chinese medicine for treating spleen-kidney yang deficiency obstinate phlegm blood type esophageal cancer | |
| Shealy | The Healing Remedies Sourcebook: Over 1000 Natural Remedies to Prevent and Cure Common Ailments | |
| CN1091019A (en) | Body-building oral liquor | |
| CN105902600A (en) | Yaotongling wine and preparation method thereof | |
| CN107115483B (en) | Pharmaceutical composition for treating muscular dystrophy and myasthenia and application thereof | |
| Wilson | Useful prescriptions | |
| Ni | Secrets of Longevity: Acupressure Healing | |
| Agrawal et al. | CRITICAL REVIEW OF KALKA KALPANA (AN AYURVEDIC DOSAGE FORM) FROM SUSHRUTA SAMHITA | |
| CN118512517A (en) | Traditional Chinese medicine composition for treating seborrheic alopecia, traditional Chinese medicine lotion and preparation method of traditional Chinese medicine lotion | |
| CN104383441A (en) | Method for preparing Chinese patent medicine for treating postpartum depression | |
| CN104643071B (en) | Health product capable of relieving fatigue | |
| Kayne et al. | Indian ayurvedic medicine |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20230411 |