CN115943952A - Suspending agent containing pyraclostrobin and flumorph and preparation method thereof - Google Patents
Suspending agent containing pyraclostrobin and flumorph and preparation method thereof Download PDFInfo
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Abstract
The invention provides a suspending agent and a preparation method thereof, belonging to the field of pesticides. The suspending agent comprises pyraclostrobin, flumorph, a wetting agent, a dispersing agent, a thickening agent, an antifreezing agent and water; the wetting agent is a sulfonate wetting agent 8070 and a block copolymer wetting agent T/304, and the dispersing agent is a polycarboxylate comb copolymer dispersing agent 4913 and a carboxylate dispersing agent RD-95. When the particle size of the suspending agent is less than or equal to 900nm, the suspending agent still has good particle size stability and control effect, and has good application prospect.
Description
Technical Field
The invention relates to the field of pesticides, and particularly relates to a suspending agent containing pyraclostrobin and flumorph and a preparation method thereof.
Technical Field
Pyraclostrobin, also known as chlorphenamine maleate, pyraclostrobin and the like, is a methoxy acrylate broad-spectrum bactericide and is mainly used for preventing and treating various diseases caused by fungi on crops. The action mechanism is that the electron transfer in the synthesis process of cytochrome is prevented, the respiration of mitochondria is inhibited, and finally cell death is caused. And can make crops absorb more nitrogen to promote the growth of the crops.
The flumorph is named Mike, is a fluorine-containing diphenyl acryllothine bactericide, is a novel systemic fusidic amine bactericide, is mainly used for preventing and treating downy mildew and phytophthora diseases, and is particularly used for preventing and treating resistant diseases. The sterilization mechanism of the morpholine compounds is generally that the fibrous actin is directly or indirectly interfered to inhibit the biosynthesis of ergosterol of pathogenic bacteria.
As is known, the smaller the particle size, the better the pesticide effect, but with the reduction of the size, the specific surface area of the particles increases rapidly, when the size reaches the nanometer level, the particles have very high surface energy, the particles are easy to aggregate, namely the stability of normal storage and heat storage is greatly reduced, and the particle size is stabilized at the nanometer level by screening proper dispersing agents and wetting agents, so that the pesticide effect is better exerted.
In the suspending agent, it is very difficult to ensure the heat storage stability of the low-melting-point raw pesticide, and especially the melting point of the pyraclostrobin is further reduced after the suspending agent is compounded with flumorph.
Therefore, a suspending agent containing pyraclostrobin and flumorph, which has small particle size, good particle size stability and good normal storage and heat storage stability, is still needed.
Disclosure of Invention
In order to solve the above technical problems, the present invention provides the following technical solutions.
In a first aspect, the present invention provides a suspension concentrate.
A suspension concentrate, comprising: pyraclostrobin, flumorph, wetting agent, dispersant, thickener, antifreezing agent and water; the wetting agent is a sulfonate wetting agent 8070 and a block copolymer wetting agent T/304, and the dispersing agent is a polycarboxylate comb copolymer dispersing agent 4913 and a carboxylate dispersing agent RD-95.
In some embodiments, the thickener is selected from one or both of xanthan gum, magnesium aluminum silicate.
In some embodiments, the anti-freeze agent is selected from one or more of ethylene glycol, propylene glycol, glycerol.
In some embodiments, based on the total mass of the suspending agent, the pyraclostrobin is 5.00wt% to 15.00wt%, the flumorph is 15.00wt% to 25.00wt%, the wetting agent is 3.00wt% to 6.00wt%, the dispersant is 4.00wt% to 10.00wt%, the thickener is 0.50wt% to 2.00wt%, the antifreeze is 3.00wt% to 6.00wt%, the water is 36.00wt% to 69.50wt%, or the balance is water.
In some embodiments, the pyraclostrobin is 10.00wt%, the flumorph is 20.00wt%, the wetting agent is 3.00wt%, the dispersant is 6.00wt% to 8.00wt%, the thickener is 0.62wt%, the antifreeze is 5.00wt%, and the balance is water, based on the total mass of the suspending agent.
In some embodiments, the wetting agents are sulfonate wetting agents 8070 and block copolymer wetting agents T/304, the dispersants are polycarboxylate comb copolymer dispersant 4913 and carboxylate dispersant RD-95; the thickening agent is xanthan gum and magnesium aluminum silicate; calculated by the total mass of the suspending agent, the content of the pyraclostrobin is 10.00wt%, the content of the flumorph is 20.00wt%, the content of the sulfonate wetting agent 8070 is 1.00wt%, the content of the block copolymer wetting agent T/304 is 2.00wt%, the content of the polycarboxylate comb copolymer dispersing agent 4913 is 2.00wt% -4.00wt%, the content of the carboxylate dispersing agent RD-95 is 2.00wt% -4.00wt%, the content of the xanthan gum is 0.12wt%, the content of the magnesium aluminum silicate is 0.5wt%, the content of the antifreezing agent is 5.00wt%, and the balance is water.
In some embodiments, the wetting agent is a sulfonate wetting agent 8070 and a block copolymer wetting agent T/304, the dispersant is a polycarboxylate comb copolymer dispersant 4913 and a carboxylate dispersant RD-95; the thickening agent is xanthan gum and magnesium aluminum silicate; the antifreeze is at least one of ethylene glycol and propylene glycol; calculated by the total mass of the suspending agent, the content of the pyraclostrobin is 10.00wt%, the content of the flumorph is 20.00wt%, the content of the sulfonate wetting agent 8070 is 1.00wt%, the content of the block copolymer wetting agent T/304 is 2.00wt%, the content of the polycarboxylate comb copolymer dispersing agent 4913 is 2.00wt% -4.00wt%, the content of the carboxylate dispersing agent RD-95 is 2.00wt% -4.00wt%, the content of the xanthan gum is 0.12wt%, the content of the magnesium aluminum silicate is 0.5wt%, the content of the antifreezing agent is 5.00wt%, and the balance is water.
In some preferred embodiments, the wetting agents are sulfonate wetting agents 8070 and block copolymer wetting agents T/304, the dispersants are polycarboxylate comb copolymer dispersant 4913 and carboxylate dispersant RD-95; the thickening agent is xanthan gum and magnesium aluminum silicate; the antifreezing agent is propylene glycol; calculated by the total mass of the suspending agent, the content of the pyraclostrobin is 10.00wt%, the content of the flumorph is 20.00wt%, the content of the sulfonate wetting agent 8070 is 1.00wt%, the content of the block copolymer wetting agent T/304 is 2.00wt%, the content of the polycarboxylate comb copolymer dispersing agent 4913 is 2.00wt%, the content of the carboxylate dispersing agent RD-95 is 4.00wt%, the content of the xanthan gum is 0.12wt%, the content of the magnesium aluminum silicate is 0.5wt%, the content of the antifreezing agent is 5.00wt%, and the balance is water.
In some preferred embodiments, the wetting agents are sulfonate wetting agents 8070 and block copolymer wetting agents T/304, the dispersants are polycarboxylate comb copolymer dispersant 4913 and carboxylate dispersant RD-95; the thickening agent is xanthan gum and magnesium aluminum silicate; the antifreezing agent is propylene glycol; calculated by the total mass of the suspending agent, the content of the pyraclostrobin is 10.00wt%, the content of the flumorph is 20.00wt%, the content of the sulfonate wetting agent 8070 is 1.00wt%, the content of the block copolymer wetting agent T/304 is 2.00wt%, the content of the polycarboxylate comb copolymer dispersing agent 4913 is 4.00wt%, the content of the carboxylate dispersing agent RD-95 is 2.00wt%, the content of the xanthan gum is 0.12wt%, the content of the magnesium aluminum silicate is 0.5wt%, the content of the antifreezing agent is 5.00wt%, and the balance is water.
In some more preferred embodiments, the wetting agents are sulfonate wetting agents 8070 and block copolymer wetting agents T/304, the dispersants are polycarboxylate comb copolymer dispersant 4913 and carboxylate dispersant RD-95; the thickening agent is xanthan gum and magnesium aluminum silicate; the antifreeze is selected from propylene glycol; calculated by the total mass of the suspending agent, the content of the pyraclostrobin is 10.00wt%, the content of the flumorph is 20.00wt%, the content of the sulfonate wetting agent 8070 is 1.00wt%, the content of the block copolymer wetting agent T/304 is 2.00wt%, the content of the polycarboxylate comb copolymer dispersing agent 4913 is 4.00wt%, the content of the carboxylate dispersing agent RD-95 is 4.00wt%, the content of the xanthan gum is 0.12wt%, the content of the magnesium aluminum silicate is 0.5wt%, the content of the antifreezing agent is 5.00wt%, and the balance is water. By adopting the technical scheme, the particle size stability of the obtained suspending agent is improved.
In some more preferred embodiments, the wetting agents are sulfonate wetting agents 8070 and block copolymer wetting agents T/304, the dispersants are polycarboxylate comb copolymer dispersant 4913 and carboxylate dispersant RD-95; the thickening agent is xanthan gum and magnesium aluminum silicate; the antifreeze is selected from ethylene glycol; calculated by the total mass of the suspending agent, the content of the pyraclostrobin is 10.00wt%, the content of the flumorph is 20.00wt%, the content of the sulfonate wetting agent 8070 is 1.00wt%, the content of the block copolymer wetting agent T/304 is 2.00wt%, the content of the polycarboxylate comb copolymer dispersing agent 4913 is 4.00wt%, the content of the carboxylate dispersing agent RD-95 is 4.00wt%, the content of the xanthan gum is 0.12wt%, the content of the magnesium aluminum silicate is 0.5wt%, the content of the antifreezing agent is 5.00wt%, and the balance is water. By adopting the technical scheme, the particle size stability of the obtained suspending agent is improved.
In some embodiments, the particle size of the material in the suspension concentrate, D98, is < 1000nm.
In some embodiments, the particle size D98 of the material in the suspending agent is less than or equal to 900nm.
In some embodiments, the particle size D98 of the material in the suspending agent is more than or equal to 600nm and less than 1000nm.
In some embodiments, the particle size D98 of the material in the suspending agent is more than or equal to 600nm and less than or equal to 900nm (i.e. 600nm-900 nm).
In a second aspect, the present invention provides a process for the preparation of the suspension formulation of the first aspect.
In some embodiments of the present invention, a method for preparing a suspension concentrate according to the first aspect comprises:
step S1a: mixing a wetting agent, a dispersing agent and an antifreezing agent with water to obtain a mixed solution A;
step S2a: mixing pyraclostrobin, flumorph and thickener with the mixed solution A, and homogenizing and dispersing to obtain mixed solution B;
step S3a: and grinding the mixed solution B until the particle size D98 of the material is less than or equal to 900nm to obtain the suspending agent.
In some preferred embodiments of the present invention, a method of preparing the suspending agent of the first aspect, the wetting agent in the suspending agent is sulfonate wetting agent 8070 and block copolymer wetting agent T/304; the preparation method comprises the following steps:
step S1b: mixing the sulfonate wetting agent 8070, the dispersant and the antifreezing agent with water to obtain a mixed solution C;
step S2b: mixing pyraclostrobin, flumorph and a thickening agent with the mixed solution C, and homogenizing and dispersing to obtain a mixed solution D;
step S3b: grinding the mixed solution D until the particle size D98 of the material is 1.5-2.0 μm, adding a block copolymer wetting agent T/304, and continuously grinding until the particle size D98 of the material is less than or equal to 900nm to obtain the suspending agent. The mixed solution D is firstly ground until the particle size D98 of the material is 1.5-2.0 mu m, then the block copolymer wetting agent T/304 is added, and the operation mode of continuous grinding is adopted, so that the stability of the heat storage particle size of the obtained suspending agent is improved.
In some embodiments, the time for the homogeneous dispersion is 100min to 300min, and the rotation speed for the homogeneous dispersion is 1000rpm to 2000rpm.
Advantageous effects
Compared with the prior art, one embodiment provided by the invention has at least one of the following beneficial effects:
(1) Compared with the preparation method of grinding after adding the wetting agent, the dispersing agent, the antifreezing agent, the pyraclostrobin, the flumorph and the thickening agent, the operation mode that the mixed solution D (containing the wetting agent 1, the dispersing agent, the antifreezing agent, the pyraclostrobin, the flumorph and the thickening agent) is ground firstly until the particle size D98 of the material is 1.5-2.0 mu m, and then the block copolymer wetting agent T/304 is added for continuous grinding is adopted, is more beneficial to improving the particle size stability of the obtained suspending agent, and is further more beneficial to improving the control effect stability of the product after stable lofting.
(2) Compared with other wetting agents or other wetting agent combinations, the 8070 and the T/304 are adopted as the wetting agents, so that the particle size stability of the suspending agent containing pyraclostrobin and flumorph with the particle size of less than 1.000 mu m of the obtained material is improved, and the stability of the control effect of the product after stability lofting is improved.
(3) Compared with other dispersing agents or a combination of dispersing agents, the adoption of RD-95 and 4913 as dispersing agents is more beneficial to improving the particle size stability of the suspending agent containing pyraclostrobin and flumorph with the particle size of the obtained material being less than 1.000 mu m, and is further more beneficial to improving the control effect stability of the product after stability lofting.
(4) Compared with other formulas, the formula provided by the invention is more favorable for improving the particle size stability of the suspending agent containing pyraclostrobin and flumorph with the material particle size less than 1.000 microns, and is further favorable for improving the control effect stability of the product after stability lofting.
(5) Compared with the formulas of the embodiment 1 and the embodiment 2, the formulas of the embodiment 3, the embodiment 4 and the embodiment 5 are more favorable for improving the particle size stability of the obtained suspending agent, and further are more favorable for improving the control effect stability of the product after stability lofting.
Definition of terms
In the context of the present invention, all numbers disclosed herein are approximate values, regardless of whether the word "about" or "approximately" is used. Based on the numbers disclosed, the numerical values of each number may vary by less than + -10% or reasonably as recognized by one of ordinary skill in the art, such as by + -1%, + -2%, + -3%, + -4%, or + -5%.
The terms "above", "below", "within" and the like are to be understood as including the instant numbers, e.g., two or more means ≧ two.
The term "and/or" should be understood to mean any one of the options or a combination of any two or more of the options.
The term "wt%" means mass percentage.
The term "plurality" means at least two, such as 2, 3, 4 or 5, and the like.
In the description herein, references to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above are not necessarily intended to refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, various embodiments or examples and features of different embodiments or examples described in this specification can be combined and combined by one skilled in the art without contradiction.
Detailed Description
In order to make the technical solutions of the present invention better understood by those skilled in the art, some non-limiting examples are further disclosed below to further explain the present invention in detail.
The reagents used in the invention are either commercially available or can be prepared by the methods described herein.
The term "hot storage" means that the sample is stored in a sample bottle and measured for the prescribed items after storage at (54. + -. 2). Degree.C.
The term "constant storage" means that a sample is stored in a sample bottle at ordinary temperature (25. + -. 2 ℃ C.) and then measured for a prescribed item.
The invention adopts the following auxiliary materials in full scale and manufacturers:
example 1-example 5: preparation of the suspending agent
Prescription: see table 1.
Table 1: formulation of suspending agents
The preparation method comprises the following steps:
preparation methods of examples 1 to 4:
step S1a: mixing a wetting agent 1, a wetting agent 2, a dispersing agent and an antifreezing agent with water to obtain a mixed solution A;
step S2a: mixing pyraclostrobin, flumorph and thickener with the mixed solution A, and homogenizing and dispersing at 1200rpm for 180min to obtain mixed solution B;
step S3a: and grinding the mixed solution B until the particle size D98 of the material is less than or equal to 900nm to obtain the suspending agent.
Preparation of example 5:
step S1b: mixing a sulfonate wetting agent 8070 (wetting agent 1), a dispersing agent and an antifreezing agent with water to obtain a mixed solution C;
step S2b: mixing pyraclostrobin, flumorph and thickener with the mixed solution C, and homogenizing and dispersing at 1200rpm for 180min to obtain mixed solution D;
step S3b: and grinding the mixed solution D until the particle size D98 of the material is 1.5-2.0 mu m, adding a block copolymer wetting agent T/304 (wetting agent 2), and continuously grinding until the particle size D98 of the material is less than or equal to 900nm to obtain the suspending agent.
Comparative examples 1 to 6: examination of wetting Agents
Prescription: a review of the wetting agents was made based on the recipe of example 5, with the specific recipe given in Table 2.
Table 2: wetting agent prescription
The preparation method comprises the following steps:
step S1b: mixing the wetting agent 1, the dispersing agent and the antifreezing agent with water to obtain a mixed solution E;
step S2b: mixing pyraclostrobin, flumorph and thickener with the mixed solution E, and homogenizing and dispersing at 1200rpm for 180min to obtain mixed solution F;
step S3b: grinding the mixed solution F until the particle size D98 of the material is 1.5-2.0 μm, adding a wetting agent 2, and continuously grinding until the particle size D98 of the material is less than or equal to 900nm to obtain the suspending agent.
Comparative examples 7 to 12: examination of dispersant
Prescription: a review of the dispersant was made based on the formulation of example 5, with the specific formulation given in Table 3.
Table 3: examination of dispersant
The preparation method comprises the following steps:
step S1b: mixing the wetting agent 1, the dispersing agent and the antifreezing agent with water to obtain a mixed solution E;
step S2b: mixing pyraclostrobin, flumorph and thickener with the mixed solution E, and homogenizing and dispersing at 1200rpm for 180min to obtain mixed solution F;
step S3b: grinding the mixed solution F until the particle size D98 of the material is 1.5-2.0 μm, adding a wetting agent 2, and continuously grinding until the particle size D98 of the material is less than or equal to 900nm to obtain the suspending agent.
Comparative examples 13 to 15: investigation of other prescriptions
Prescription: see table 4.
Table 4: other prescriptions
Test example 1: investigation of particle size stability
The suspensions obtained in examples 1 to 5 and comparative examples 1 to 12 were measured for the primary particle size D98, the particle size D98 in 150 days in ordinary storage and the particle size D98 in 14 days in hot storage, respectively, and the results are shown in tables 5 to 8.
Table 5: example 1-example 5 particle size stability test results
| Sample numbering | Example 1 | Example 2 | Example 3 | Example 4 | Examples5 |
| Particle size of the initial slurry, D98, μm | 0.651 | 0.644 | 0.640 | 0.643 | 0.638 |
| The grain diameter D98 is mum after being stored for 30 days | 0.709 | 0.753 | 0.647 | 0.651 | 0.656 |
| Particle diameter D98, mum of 150 days after normal storage | 0.722 | 0.773 | 0.651 | 0.661 | 0.663 |
| Particle size D98, μm in hot storage for 14 days | 1.168 | 1.562 | 0.816 | 0.828 | 0.702 |
Table 6: results of examining particle size stability of the suspensions obtained in comparative examples 1 to 6
Table 7: results of examining particle size stability of the suspension obtained in comparative examples 7 to 12
Table 8: results of examining particle size stability of the suspensions obtained in comparative examples 13 to 16
| Sample numbering | Comparative example 13 | Comparative example 14 | Comparative example 15 | Comparative example 16 |
| Particle size of the initial slurry, D98, μm | 0.639 | 0.667 | 0.653 | 0.635 |
| The grain diameter D98 is mum after being stored for 30 days | 1.840 | 1.598 | 1.728 | 1.957 |
| Particle diameter D98, mum of 150 days after normal storage | 2.663 | 2.036 | 2.658 | 2.719 |
| Particle size D98, μm in hot storage for 14 days | 6.416 | 6.537 | 5.934 | 4.767 |
And (4) conclusion:
(1) Compared with the preparation method of adding the wetting agent, the dispersing agent, the antifreezing agent, the pyraclostrobin, the flumorph and the thickening agent and then grinding, the operation mode that the mixed solution D (containing the wetting agent 1, the dispersing agent, the antifreezing agent, the pyraclostrobin, the flumorph and the thickening agent) is ground firstly until the particle size D98 of the material is 1.5-2.0 mu m, and then the block copolymer wetting agent T/304 is added for continuous grinding is adopted is more beneficial to improving the stability of the heat storage particle size of the obtained suspending agent.
(2) Compared with other wetting agents or other wetting agent combinations, the 8070 and the T/304 are adopted as the wetting agents, so that the particle size stability of the suspending agent containing the pyraclostrobin and the flumorph with the particle size of less than 1.000 mu m of the obtained material is improved.
(3) Compared with other dispersants or dispersant combinations, the application of RD-95 and 4913 as dispersants is more favorable for improving the particle size stability of the suspending agent containing pyraclostrobin and flumorph, wherein the particle size of the obtained material is less than 1.000 microns.
(4) Compared with other formulas, the formula provided by the invention is more favorable for improving the particle size stability of the suspending agent containing pyraclostrobin and flumorph, wherein the particle size of the suspending agent is less than 1.000 mu m.
(5) The formulations of examples 3, 4 and 5 are more advantageous to improve the particle size stability of the resulting suspension than the formulations of examples 1 and 2.
Test example 2: test example for field control
1. Controlling cucumber downy mildew of a subject
2. Experimental medicament
3. Method of administering a drug
The test is carried out in the flowering and fruiting period of the cucumber, the early stage of cucumber downy mildew attack, the application is carried out for 3 times, each time is 10 days apart, and the application is carried out on the positive and negative sides of the leaves; adding water 600 liters per hectare.
The disease condition base was investigated before the administration of the drug, and the investigation was carried out before each administration and 10 days after the last administration.
The investigation method comprises the following steps: randomly sampling in each cell, checking 2 plants at each point, checking 8 plants in total, investigating all leaves in each plant, and recording the total leaf number, the diseased leaf number and the diseased grade number. The disease index (abbreviated as disease index) and the prevention and treatment effect were calculated by examining the recorded data, and the results are shown in table 9.
The disease grading method comprises the following steps:
level 0: no diseases exist;
level 1: the lesion area accounts for less than 5% of the whole leaf area;
and 3, level: the lesion area accounts for 6 to 10 percent of the whole leaf area;
and 5, stage: the lesion area accounts for 11% -25% of the whole leaf area;
and 7, stage: the lesion area accounts for 26-50% of the whole leaf area;
and 9, stage: the lesion area accounts for more than 50% of the whole leaf area;
the drug effect is calculated according to the following formula:
in the formula: CK (CK) 0 : disease index before drug administration in blank control zone;
CK 1 : disease index after drug administration in the blank control area;
PT 0 : pre-drug index in the drug treatment area;
PT 1 : disease index after drug administration in the drug treatment area.
Table 9: test of field control effect
And (4) conclusion:
(1) Compared with the preparation method of grinding after adding the wetting agent, the dispersing agent, the antifreezing agent, the pyraclostrobin, the flumorph and the thickening agent, the operation mode that the mixed solution D (containing the wetting agent 1, the dispersing agent, the antifreezing agent, the pyraclostrobin, the flumorph and the thickening agent) is ground firstly until the particle size D98 of the material is 1.5-2.0 mu m, and then the block copolymer wetting agent T/304 is added for continuous grinding is adopted, is more beneficial to improving the particle size stability of the obtained suspending agent, and is further more beneficial to improving the control effect stability of the product after stable lofting.
(2) Compared with other wetting agents or other wetting agent combinations, the 8070 and the T/304 are adopted as the wetting agents, so that the particle size stability of the suspending agent containing pyraclostrobin and flumorph with the particle size of less than 1.000 mu m of the obtained material is improved, and the stability of the control effect of the product after stability lofting is improved.
(3) Compared with other dispersing agents or a combination of dispersing agents, the adoption of RD-95 and 4913 as dispersing agents is more beneficial to improving the particle size stability of the suspending agent containing pyraclostrobin and flumorph with the particle size of the obtained material being less than 1.000 mu m, and is further more beneficial to improving the control effect stability of the product after stability lofting.
(4) Compared with other formulas, the formula provided by the invention is more favorable for improving the particle size stability of the suspending agent containing pyraclostrobin and flumorph, with the particle size of the material being less than 1.000 microns, and further is more favorable for improving the control effect stability of the product after stability lofting.
While the methods of the present invention have been described in terms of preferred embodiments, it will be apparent to those of ordinary skill in the art that variations and modifications of the methods and applications described herein, as well as other suitable variations and combinations, may be made to implement and use the techniques of the present invention within the context, spirit and scope of the invention. Those skilled in the art can modify the process parameters appropriately in view of the disclosure herein. It is expressly intended that all such similar substitutes and modifications which would be obvious to those skilled in the art are deemed to be included within the invention.
Claims (9)
1. A suspension concentrate, comprising: pyraclostrobin, flumorph, wetting agent, dispersant, thickener, antifreezing agent and water; the wetting agent is a sulfonate wetting agent 8070 and a block copolymer wetting agent T/304, and the dispersing agent is a polycarboxylate comb copolymer dispersing agent 4913 and a carboxylate dispersing agent RD-95.
2. The suspension concentrate according to claim 1, wherein the thickener is one or two selected from xanthan gum, magnesium aluminum silicate.
3. Nanosuspension according to any one of claims 1 to 2, wherein the antifreeze agent is selected from one or more of ethylene glycol, propylene glycol, glycerol.
4. The suspending agent according to any one of claims 1 to 3, wherein the pyraclostrobin is 5.00wt% to 15.00wt%, the flumorph is 15.00wt% to 25.00wt%, the wetting agent is 3.00wt% to 6.00wt%, the dispersant is 4.00wt% to 10.00wt%, the thickener is 0.50wt% to 2.00wt%, the antifreeze is 3.00wt% to 6.00wt%, the water is 36.00wt% to 69.50wt% or the balance is water; or alternatively
Calculated by the total mass of the suspending agent, the content of the pyraclostrobin is 10.00wt%, the content of the flumorph is 20.00wt%, the content of the wetting agent is 3.00wt%, the content of the dispersing agent is 6.00wt% -8.00wt%, the content of the thickening agent is 0.62wt%, the content of the antifreezing agent is 5.00wt%, and the balance is water.
5. The suspension concentrate as claimed in any of claims 1-4, said wetting agent is a sulfonate wetting agent 8070 and a block copolymer wetting agent T/304, said dispersant is a polycarboxylate comb copolymer dispersant 4913 and a carboxylate dispersant RD-95; the thickening agent is xanthan gum and aluminum magnesium silicate; calculated by the total mass of the suspending agent, the content of the pyraclostrobin is 10.00wt%, the content of the flumorph is 20.00wt%, the content of the sulfonate wetting agent 8070 is 1.00wt%, the content of the block copolymer wetting agent T/304 is 2.00wt%, the content of the polycarboxylate comb copolymer dispersing agent 4913 is 2.00wt% -4.00wt%, the content of the carboxylate dispersing agent RD-95 is 2.00wt% -4.00wt%, the content of the xanthan gum is 0.12wt%, the content of the magnesium aluminum silicate is 0.5wt%, the content of the antifreezing agent is 5.00wt%, and the balance is water; or
The wetting agent is a sulfonate wetting agent 8070 and a block copolymer wetting agent T/304, and the dispersing agent is a polycarboxylate comb copolymer dispersing agent 4913 and a carboxylate dispersing agent RD-95; the thickening agent is xanthan gum and magnesium aluminum silicate; the antifreeze is at least one of ethylene glycol and propylene glycol; calculated by the total mass of the suspending agent, the content of the pyraclostrobin is 10.00wt%, the content of the flumorph is 20.00wt%, the content of the sulfonate wetting agent 8070 is 1.00wt%, the content of the block copolymer wetting agent T/304 is 2.00wt%, the content of the polycarboxylate comb copolymer dispersing agent 4913 is 2.00wt% -4.00wt%, the content of the carboxylate dispersing agent RD-95 is 2.00wt% -4.00wt%, the content of the xanthan gum is 0.12wt%, the content of the magnesium aluminum silicate is 0.5wt%, the content of the antifreezing agent is 5.00wt%, and the balance is water; or
The wetting agent is a sulfonate wetting agent 8070 and a block copolymer wetting agent T/304, and the dispersing agent is a polycarboxylate comb copolymer dispersing agent 4913 and a carboxylate dispersing agent RD-95; the thickening agent is xanthan gum and aluminum magnesium silicate; the antifreezing agent is propylene glycol; calculated by the total mass of the suspending agent, the content of the pyraclostrobin is 10.00wt%, the content of the flumorph is 20.00wt%, the content of the sulfonate wetting agent 8070 is 1.00wt%, the content of the block copolymer wetting agent T/304 is 2.00wt%, the content of the polycarboxylate comb copolymer dispersing agent 4913 is 2.00wt%, the content of the carboxylate dispersing agent RD-95 is 4.00wt%, the content of the xanthan gum is 0.12wt%, the content of the magnesium aluminum silicate is 0.5wt%, the content of the antifreezing agent is 5.00wt%, and the balance is water; or
The wetting agent is a sulfonate wetting agent 8070 and a block copolymer wetting agent T/304, and the dispersing agent is a polycarboxylate comb copolymer dispersing agent 4913 and a carboxylate dispersing agent RD-95; the thickening agent is xanthan gum and magnesium aluminum silicate; the antifreezing agent is propylene glycol; calculated by the total mass of the suspending agent, the content of the pyraclostrobin is 10.00wt%, the content of the flumorph is 20.00wt%, the content of the sulfonate wetting agent 8070 is 1.00wt%, the content of the block copolymer wetting agent T/304 is 2.00wt%, the content of the polycarboxylate comb copolymer dispersing agent 4913 is 4.00wt%, the content of the carboxylate dispersing agent RD-95 is 2.00wt%, the content of the xanthan gum is 0.12wt%, the content of the magnesium aluminum silicate is 0.5wt%, the content of the antifreezing agent is 5.00wt%, and the balance is water; or
The wetting agent is a sulfonate wetting agent 8070 and a block copolymer wetting agent T/304, and the dispersing agent is a polycarboxylate comb copolymer dispersing agent 4913 and a carboxylate dispersing agent RD-95; the thickening agent is xanthan gum and magnesium aluminum silicate; the antifreeze is selected from propylene glycol; calculated by the total mass of the suspending agent, the content of the pyraclostrobin is 10.00wt%, the content of the flumorph is 20.00wt%, the content of the sulfonate wetting agent 8070 is 1.00wt%, the content of the block copolymer wetting agent T/304 is 2.00wt%, the content of the polycarboxylate comb copolymer dispersing agent 4913 is 4.00wt%, the content of the carboxylate dispersing agent RD-95 is 4.00wt%, the content of the xanthan gum is 0.12wt%, the content of the magnesium aluminum silicate is 0.5wt%, the content of the antifreezing agent is 5.00wt%, and the balance is water; or
The wetting agent is a sulfonate wetting agent 8070 and a block copolymer wetting agent T/304, and the dispersing agent is a polycarboxylate comb copolymer dispersing agent 4913 and a carboxylate dispersing agent RD-95; the thickening agent is xanthan gum and magnesium aluminum silicate; the antifreeze is selected from ethylene glycol; calculated by the total mass of the suspending agent, the content of the pyraclostrobin is 10.00wt%, the content of the flumorph is 20.00wt%, the content of the sulfonate wetting agent 8070 is 1.00wt%, the content of the block copolymer wetting agent T/304 is 2.00wt%, the content of the polycarboxylate comb copolymer dispersing agent 4913 is 4.00wt%, the content of the carboxylate dispersing agent RD-95 is 4.00wt%, the content of the xanthan gum is 0.12wt%, the content of the magnesium aluminum silicate is 0.5wt%, the content of the antifreezing agent is 5.00wt%, and the balance is water.
6. A suspension as claimed in any one of claims 1 to 5, wherein the particle size D98 of the material in the suspension is < 1000nm or the particle size D98 of the material in the suspension is < 900nm or the particle size D98 of the material in the suspension is 600nm to 900nm.
7. A process for preparing a suspension concentrate as claimed in any of claims 1 to 6 which comprises:
step S1a: mixing a wetting agent, a dispersing agent and an antifreezing agent with water to obtain a mixed solution A;
step S2a: mixing pyraclostrobin, flumorph and thickener with the mixed solution A, and homogenizing and dispersing to obtain mixed solution B;
step S3a: and grinding the mixed solution B until the particle size D98 of the material is less than or equal to 900nm to obtain the suspending agent.
8. A process for preparing the suspending agent of any one of claims 1 to 6 wherein the wetting agent in the suspending agent is a sulfonate wetting agent 8070 and a block copolymer wetting agent T/304; the preparation method comprises the following steps:
step S1b: mixing the sulfonate wetting agent 8070, the dispersant and the antifreezing agent with water to obtain a mixed solution C;
step S2b: mixing pyraclostrobin, flumorph and a thickening agent with the mixed solution C, and homogenizing and dispersing to obtain a mixed solution D;
step S3b: grinding the mixed solution D until the particle size D98 of the material is 1.5-2.0 μm, adding a block copolymer wetting agent T/304, and continuously grinding until the particle size D98 of the material is less than or equal to 900nm to obtain the suspending agent.
9. The production method according to any one of claims 7 to 8, wherein the time for the homogeneous dispersion is 100min to 300min, and the rotation speed for the homogeneous dispersion is 1000rpm to 2000rpm.
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