CN115896120A - 表达免疫功能调控因子的免疫活性细胞及表达载体 - Google Patents
表达免疫功能调控因子的免疫活性细胞及表达载体 Download PDFInfo
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| PCT/JP2017/010437 WO2017159736A1 (ja) | 2016-03-17 | 2017-03-15 | 免疫機能制御因子を発現する免疫担当細胞及び発現ベクター |
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| WO2018119518A1 (en) | 2017-01-01 | 2018-07-05 | Lee Chi Yu Gregory | Rp215 chimeric antigen receptor construct and methods of making and using same |
| EP3604344A4 (en) * | 2017-03-27 | 2021-01-06 | Noile-Immune Biotech, Inc. | CHIMERIC ANTIGEN RECEPTOR |
| BR112020006746A2 (pt) * | 2017-10-10 | 2020-10-06 | Yamaguchi University | intensificador para células t ou células b, composição farmacêutica, inibidor da recorrência de tumor maligno, e, indutor para induzir uma função de memória em células t ou células b |
| AU2018388079A1 (en) | 2017-12-24 | 2020-07-16 | Noile-Immune Biotech, Inc. | Immunocompetent cell that expresses a cell surface molecule specifically recognizing human mesothelin, IL-7 and CCL19 |
| CN112154204A (zh) | 2018-05-15 | 2020-12-29 | 科济生物医药（上海）有限公司 | 基因工程化的细胞及应用 |
| IL292542A (en) * | 2019-10-28 | 2022-06-01 | Noile Immune Biotech Inc | A drug for the treatment of cancer, a mixture of drugs, a medicinal preparation, a cell that responds to an immune campaign, a carrier for the transfer of nucleic acids and a product |
| CN111849910B (zh) | 2020-05-27 | 2021-06-15 | 南京北恒生物科技有限公司 | 工程化免疫细胞及其用途 |
| EP4372089A1 (en) | 2021-07-16 | 2024-05-22 | Noile-Immune Biotech Inc. | Chimeric antigen receptor, cell capable of expressing said receptor, pharmaceutical composition containing said cell, method for producing said cell, and polynucleotide or vector which contains nucleotide sequence encoding said chimeric antigen receptor |
| CA3225682A1 (en) | 2021-07-16 | 2023-01-19 | Koji Tamada | Anti-egfrviii antibody, polypeptide, cell capable of expressing said polypeptide, pharmaceutical composition comprising said cell, method for producing said cell, and polynucleotide or vector comprising nucleotide sequence encoding said polypeptid |
| AU2022318416A1 (en) * | 2021-07-29 | 2024-01-25 | Takeda Pharmaceutical Company Limited | Engineered immune cell that specifically targets mesothelin and uses thereof |
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| CN103038343A (zh) | 2010-03-23 | 2013-04-10 | 英特瑞克斯顿股份有限公司 | 条件表达治疗蛋白的载体，包含所述载体的宿主细胞，及其应用 |
| PL3214091T3 (pl) | 2010-12-09 | 2019-03-29 | The Trustees Of The University Of Pennsylvania | Zastosowanie komórek T modyfikowanych chimerycznymi receptorami antygenowymi do leczenia nowotworów |
| AU2011343887B2 (en) * | 2010-12-14 | 2016-06-16 | University Of Maryland, Baltimore | Universal anti-tag chimeric antigen receptor-expressing T cells and methods of treating cancer |
| CN102539745B (zh) * | 2010-12-31 | 2013-03-06 | 中国人民解放军第三〇九医院 | 移植肾排斥反应早期诊断及预警试剂盒 |
| WO2013040371A2 (en) * | 2011-09-16 | 2013-03-21 | Baylor College Of Medicine | Targeting the tumor microenvironment using manipulated nkt cells |
| JP6117515B2 (ja) | 2011-11-01 | 2017-04-19 | 国立大学法人名古屋大学 | 髄膜腫治療用医薬組成物 |
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| US10420801B2 (en) * | 2012-03-21 | 2019-09-24 | The General Hospital Corporation | Isolation and use of human lymphoid organ-derived suppressive stromal cells |
| PL3597742T3 (pl) * | 2014-10-09 | 2022-11-14 | Yamaguchi University | Wektor ekspresyjny CAR oraz komórki T wykazujące ekspresję CAR |
| RU2770812C2 (ru) * | 2016-03-17 | 2022-04-22 | Ямагути Университи | Иммунокомпетентная клетка и экспрессирующий вектор, экспрессирующие регуляторные факторы иммунной функции |
| CN112226462A (zh) * | 2020-10-12 | 2021-01-15 | 广东昭泰体内生物医药科技有限公司 | 共表达分泌型il-7和选择性ccl19的表达载体及其应用 |
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