CN115884713A - 分析物传感器及用于生产分析物传感器的方法 - Google Patents

分析物传感器及用于生产分析物传感器的方法 Download PDF

Info

Publication number
CN115884713A
CN115884713A CN202180044233.XA CN202180044233A CN115884713A CN 115884713 A CN115884713 A CN 115884713A CN 202180044233 A CN202180044233 A CN 202180044233A CN 115884713 A CN115884713 A CN 115884713A
Authority
CN
China
Prior art keywords
electrode
analyte
analyte sensor
working electrode
interferer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202180044233.XA
Other languages
English (en)
Chinese (zh)
Inventor
G·霍赫穆特
A·施特克
K·斯利奥斯贝格
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of CN115884713A publication Critical patent/CN115884713A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1486Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
    • A61B5/14865Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3277Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a redox reaction, e.g. detection by cyclic voltammetry

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Electrochemistry (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
CN202180044233.XA 2020-06-23 2021-06-21 分析物传感器及用于生产分析物传感器的方法 Pending CN115884713A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20181542.0 2020-06-23
EP20181542.0A EP3928697A1 (en) 2020-06-23 2020-06-23 Analyte sensor and a method for producing an analyte sensor
PCT/EP2021/066854 WO2021259865A1 (en) 2020-06-23 2021-06-21 Analyte sensor and a method for producing an analyte sensor

Publications (1)

Publication Number Publication Date
CN115884713A true CN115884713A (zh) 2023-03-31

Family

ID=71527569

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180044233.XA Pending CN115884713A (zh) 2020-06-23 2021-06-21 分析物传感器及用于生产分析物传感器的方法

Country Status (14)

Country Link
US (2) US12507923B2 (https=)
EP (1) EP3928697A1 (https=)
JP (1) JP7733681B2 (https=)
KR (1) KR20230027013A (https=)
CN (1) CN115884713A (https=)
AR (1) AR122697A1 (https=)
AU (1) AU2021295539A1 (https=)
BR (1) BR112022025961A2 (https=)
CA (1) CA3178942A1 (https=)
IL (1) IL299118A (https=)
MX (1) MX2022015422A (https=)
TW (1) TW202222255A (https=)
WO (1) WO2021259865A1 (https=)
ZA (1) ZA202209980B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230112140A1 (en) * 2021-10-07 2023-04-13 Uxn Co., Ltd. Electrochemical sensor, continuous analyte meter including electrochemical sensor, and method of fabricating electrochemical sensor
EP4558045A1 (en) * 2022-07-18 2025-05-28 Willow Laboratories, Inc. Electrochemical devices and methods for accurate determination of analyte
CN121793901A (zh) * 2023-09-22 2026-04-03 上海移宇科技有限公司 一种结构增强型分析物传感器
US20250143610A1 (en) * 2023-11-07 2025-05-08 Laxmi Therapeutic Devices, Inc. Method for spatially constraining enzyme activity

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3847370A (en) 1972-02-16 1974-11-12 Horizon Ind Ltd Tube servicing device
US5413690A (en) 1993-07-23 1995-05-09 Boehringer Mannheim Corporation Potentiometric biosensor and the method of its use
US5762770A (en) 1994-02-21 1998-06-09 Boehringer Mannheim Corporation Electrochemical biosensor test strip
US5779665A (en) 1997-05-08 1998-07-14 Minimed Inc. Transdermal introducer assembly
US5798031A (en) 1997-05-12 1998-08-25 Bayer Corporation Electrochemical biosensor
US6129823A (en) 1997-09-05 2000-10-10 Abbott Laboratories Low volume electrochemical sensor
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US8346337B2 (en) * 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6360888B1 (en) 1999-02-25 2002-03-26 Minimed Inc. Glucose sensor package system
EP2322645A1 (en) 1999-06-18 2011-05-18 Abbott Diabetes Care Inc. Mass transport limited in vivo analyte sensor
US7291256B2 (en) 2002-09-12 2007-11-06 Lifescan, Inc. Mediator stabilized reagent compositions and methods for their use in electrochemical analyte detection assays
JP2004184155A (ja) * 2002-12-02 2004-07-02 Matsushita Electric Ind Co Ltd 唾液糖バイオセンサ及び測定方法
TR201810169T4 (tr) 2003-06-20 2018-08-27 Hoffmann La Roche Dar, homojen belirteç şeritlerinin üretilmesi için yöntem ve belirteç.
US7761130B2 (en) * 2003-07-25 2010-07-20 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US9763609B2 (en) 2003-07-25 2017-09-19 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
WO2005045417A1 (en) * 2003-10-31 2005-05-19 Lifescan Scotland Limited Method of reducing the effect of direct and mediated interference current in an electrochemical test strip
EP1962673B1 (en) 2005-12-16 2010-10-13 Bayer HealthCare, LLC Transdermal analyte sensor assembly and methods of using the same
ES2326286T3 (es) * 2005-12-19 2009-10-06 F. Hoffmann-La Roche Ag Sensor tipo sandwich para determinar la concentracion de un analito.
EP1797817A1 (de) * 2005-12-19 2007-06-20 F.Hoffmann-La Roche Ag Sandwichsensor zur Ermittlung einer Analytkonzentration
US8808515B2 (en) 2007-01-31 2014-08-19 Abbott Diabetes Care Inc. Heterocyclic nitrogen containing polymers coated analyte monitoring device and methods of use
EP1972267A1 (de) 2007-03-20 2008-09-24 Roche Diagnostics GmbH System zur in-vivo Messung einer Analytkonzentration
US20100327886A1 (en) * 2008-03-27 2010-12-30 Toshifumi Nakamura Measurement device, measurement system, and concentration measurement method
US8500990B2 (en) * 2009-04-22 2013-08-06 Nova Biomedical Corporation Electrochemical biosensors based on NAD(P)-dependent dehydrogenase enzymes
JP5753720B2 (ja) * 2010-04-22 2015-07-22 アークレイ株式会社 バイオセンサ
US20130199944A1 (en) * 2010-06-30 2013-08-08 Edwards Lifesciences Corporation Analyte sensor
CA3105324A1 (en) * 2011-06-17 2012-12-20 Abbott Diabetes Care Inc. Connectors for making connections between analyte sensors and other devices
JP6321540B2 (ja) * 2011-07-26 2018-05-09 グリセンス インコーポレイテッド 気密密閉された筐体を備える埋め込み型分析物センサおよび該センサを製造する方法
GB2505694B (en) 2012-09-07 2017-03-22 Lifescan Scotland Ltd Electrochemical-based analytical test strip with bare interferent electrodes
US9274098B2 (en) 2013-04-30 2016-03-01 Lifescan Scotland Limited Analyte meter digital sample detection
US9435764B2 (en) 2013-06-27 2016-09-06 Lifescan Scotland Limited Transient signal error trap for an analyte measurement determined from a specified sampling time derived from a sensed physical characteristic of the sample containing the analyte
CN106793943B (zh) * 2014-04-15 2018-10-30 明眸科技股份有限公司 功能性隐形眼镜以及相关的系统和方法
KR101703948B1 (ko) 2014-10-27 2017-02-07 광운대학교 산학협력단 인체 삽입형 플렉시블 바이오센서, 및 그 제조방법
US20160235347A1 (en) 2015-02-13 2016-08-18 Maarij Baig Artificial sensors and methods of manufacture thereof
CA2984959C (en) 2015-04-28 2019-10-15 Vector Surgical, Llc Device and method for clearing tubing
PL3220137T3 (pl) * 2016-03-14 2019-07-31 F. Hoffmann-La Roche Ag Sposób wykrywania udziału zakłócającego w biosensorze
US20190004000A1 (en) * 2017-07-03 2019-01-03 Arch Chemicals, Inc. Sensor for analytes
CN109406591A (zh) 2017-08-17 2019-03-01 爱科来株式会社 测定方法和测定装置
KR102173496B1 (ko) 2018-07-03 2020-11-03 광운대학교 산학협력단 제조공정이 단순화된 최소 침습형 니들 기반 바이오센서 및 그 제조방법
CN112294320B (zh) 2019-08-02 2024-06-11 华广生技股份有限公司 植入式微型生物传感器
CN111096754B (zh) * 2019-12-31 2024-08-30 上海硕创生物医药科技有限公司 一种生物传感器

Also Published As

Publication number Publication date
BR112022025961A2 (pt) 2023-01-17
JP2023532189A (ja) 2023-07-27
JP7733681B2 (ja) 2025-09-03
EP3928697A1 (en) 2021-12-29
IL299118A (en) 2023-02-01
ZA202209980B (en) 2023-06-28
US20230051071A1 (en) 2023-02-16
CA3178942A1 (en) 2021-12-30
TW202222255A (zh) 2022-06-16
US20230190155A1 (en) 2023-06-22
MX2022015422A (es) 2023-01-11
WO2021259865A1 (en) 2021-12-30
AU2021295539A1 (en) 2022-09-29
AR122697A1 (es) 2022-09-28
US12507924B2 (en) 2025-12-30
US12507923B2 (en) 2025-12-30
KR20230027013A (ko) 2023-02-27

Similar Documents

Publication Publication Date Title
JP5044655B2 (ja) 電気化学的テストストリップ用の伝達物質としてルテニウムヘキサミンを使用する試薬調合物
KR101092350B1 (ko) 2개의 다른 인가전위들을 이용한 전기화학 센서에서의 간섭감소 방법을 사용하는 계량기
JP7733681B2 (ja) 検体センサおよび検体センサを製造する方法
JP2007271623A (ja) 生理学的サンプルから対照溶液を判別するシステム及び方法
RU2702132C1 (ru) Способ детектирования вклада мешающего компонента в биосенсоре
US11774394B2 (en) Electrochemical sensor and sensor system for detecting at least one analyte
HK40093318A (zh) 分析物传感器及用於生产分析物传感器的方法
HK40095780A (zh) 用於检测至少一种分析物的电化学传感器和传感器系统
HK40029615A (en) Electrochemical sensor and sensor system for detecting at least one analyte
HK40029615B (en) Electrochemical sensor and sensor system for detecting at least one analyte
HK1261212B (zh) 用於检测生物传感器中的干扰物贡献的方法
HK1093095B (en) Electrochemical test strip for reducing the effect of direct interference current
HK1091900B (en) A meter for use in a method of reducing interferences in an electrochemical sensor using two different applied potentials

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 40093318

Country of ref document: HK