MX2022015422A - Sensor de analitos y metodo para producir un sensor de analitos. - Google Patents

Sensor de analitos y metodo para producir un sensor de analitos.

Info

Publication number
MX2022015422A
MX2022015422A MX2022015422A MX2022015422A MX2022015422A MX 2022015422 A MX2022015422 A MX 2022015422A MX 2022015422 A MX2022015422 A MX 2022015422A MX 2022015422 A MX2022015422 A MX 2022015422A MX 2022015422 A MX2022015422 A MX 2022015422A
Authority
MX
Mexico
Prior art keywords
electrode
analyte sensor
analyte
interferent
body fluid
Prior art date
Application number
MX2022015422A
Other languages
English (en)
Inventor
Gernot Hochmuth
Alexander Steck
Kyrylo Sliozberg
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX2022015422A publication Critical patent/MX2022015422A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
    • A61B5/14865—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3277—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a redox reaction, e.g. detection by cyclic voltammetry

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Electrochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)

Abstract

La presente invención se refiere a un sensor de analitos (130) para determinar una concentración de analitos en un fluido corporal (132) y un método para producir el sensor de analitos (130). El sensor de analitos (130) comprende: - un sustrato (134) que tiene una primera superficie (136), estando configurada la primera superficie (136) para orientarse hacia el fluido corporal (132) que comprende el analito; - un electrodo de trabajo (140); - un electrodo interferente (142); y - al menos un electrodo adicional (144) seleccionado del grupo que consiste de un contraelectrodo (146), un electrodo de referencia y un contraelectrodo/electrodo de referencia; en donde cada uno del electrodo de trabajo (140) y el electrodo interferente (142) comprende una capa (210) de un material conductor (212), en donde el electrodo de trabajo (140) comprende además al menos una enzima, mientras que el electrodo interferente (142) no tiene enzima, y en donde el electrodo interferente (142) y el electrodo de trabajo (140) son capas separadas eléctricamente ubicadas de manera adyacente sobre la primera superficie (136) del sustrato (134).
MX2022015422A 2020-06-23 2021-06-21 Sensor de analitos y metodo para producir un sensor de analitos. MX2022015422A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20181542.0A EP3928697A1 (en) 2020-06-23 2020-06-23 Analyte sensor and a method for producing an analyte sensor
PCT/EP2021/066854 WO2021259865A1 (en) 2020-06-23 2021-06-21 Analyte sensor and a method for producing an analyte sensor

Publications (1)

Publication Number Publication Date
MX2022015422A true MX2022015422A (es) 2023-01-11

Family

ID=71527569

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022015422A MX2022015422A (es) 2020-06-23 2021-06-21 Sensor de analitos y metodo para producir un sensor de analitos.

Country Status (14)

Country Link
US (2) US20230051071A1 (es)
EP (1) EP3928697A1 (es)
JP (1) JP2023532189A (es)
KR (1) KR20230027013A (es)
CN (1) CN115884713A (es)
AR (1) AR122697A1 (es)
AU (1) AU2021295539A1 (es)
BR (1) BR112022025961A2 (es)
CA (1) CA3178942A1 (es)
IL (1) IL299118A (es)
MX (1) MX2022015422A (es)
TW (1) TW202222255A (es)
WO (1) WO2021259865A1 (es)
ZA (1) ZA202209980B (es)

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5413690A (en) 1993-07-23 1995-05-09 Boehringer Mannheim Corporation Potentiometric biosensor and the method of its use
US5762770A (en) 1994-02-21 1998-06-09 Boehringer Mannheim Corporation Electrochemical biosensor test strip
US5779665A (en) 1997-05-08 1998-07-14 Minimed Inc. Transdermal introducer assembly
US5798031A (en) 1997-05-12 1998-08-25 Bayer Corporation Electrochemical biosensor
US6129823A (en) 1997-09-05 2000-10-10 Abbott Laboratories Low volume electrochemical sensor
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US6360888B1 (en) 1999-02-25 2002-03-26 Minimed Inc. Glucose sensor package system
AU5747100A (en) 1999-06-18 2001-01-09 Therasense, Inc. Mass transport limited in vivo analyte sensor
WO2004113901A1 (en) 2003-06-20 2004-12-29 Roche Diagnostics Gmbh Test strip with slot vent opening
US9763609B2 (en) 2003-07-25 2017-09-19 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
WO2007120442A2 (en) * 2003-07-25 2007-10-25 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
EP1797817A1 (de) * 2005-12-19 2007-06-20 F.Hoffmann-La Roche Ag Sandwichsensor zur Ermittlung einer Analytkonzentration
EP1972267A1 (de) 2007-03-20 2008-09-24 Roche Diagnostics GmbH System zur in-vivo Messung einer Analytkonzentration
WO2009119117A1 (ja) * 2008-03-27 2009-10-01 パナソニック株式会社 測定装置、測定システム、及び濃度測定方法
US8500990B2 (en) * 2009-04-22 2013-08-06 Nova Biomedical Corporation Electrochemical biosensors based on NAD(P)-dependent dehydrogenase enzymes
KR101703948B1 (ko) 2014-10-27 2017-02-07 광운대학교 산학협력단 인체 삽입형 플렉시블 바이오센서, 및 그 제조방법
US20160235347A1 (en) 2015-02-13 2016-08-18 Maarij Baig Artificial sensors and methods of manufacture thereof
PL3220137T3 (pl) 2016-03-14 2019-07-31 F. Hoffmann-La Roche Ag Sposób wykrywania udziału zakłócającego w biosensorze
TWI799725B (zh) 2019-08-02 2023-04-21 華廣生技股份有限公司 植入式微型生物感測器及其操作方法

Also Published As

Publication number Publication date
KR20230027013A (ko) 2023-02-27
JP2023532189A (ja) 2023-07-27
EP3928697A1 (en) 2021-12-29
BR112022025961A2 (pt) 2023-01-17
CN115884713A (zh) 2023-03-31
AR122697A1 (es) 2022-09-28
CA3178942A1 (en) 2021-12-30
TW202222255A (zh) 2022-06-16
WO2021259865A1 (en) 2021-12-30
US20230190155A1 (en) 2023-06-22
IL299118A (en) 2023-02-01
AU2021295539A1 (en) 2022-09-29
US20230051071A1 (en) 2023-02-16
ZA202209980B (en) 2023-06-28

Similar Documents

Publication Publication Date Title
US9753004B2 (en) Electrochemical biosensor with improved accuracy
KR100483093B1 (ko) 전기 화학 전지
DE602006006231D1 (de) Elektrochemischer Biosensor
CN1241012C (zh) 具有整体的试剂/血液隔离层的一次性试条及一次性试条的形成方法
WO2005066616A3 (en) Biosensor and method of making
TWI454245B (zh) 用於多井生物感測器之化學圖案的系統與方法
Jesny et al. Non‐enzymatic Electrochemical Sensor for the Simultaneous Determination of Xanthine, its Methyl Derivatives Theophylline and Caffeine as well as its Metabolite Uric Acid
EP1304566A4 (en) BIOSENSOR
ATE433711T1 (de) Sandwichsensor zur ermittlung einer analytkonzentration
CA2416207A1 (en) Electrochemical method for measuring chemical reaction rates
US9217723B2 (en) Co-facial analytical test strip with stacked unidirectional contact pads
WO2007053497A3 (en) Analyte sensor and method of making it
CA2635670A1 (en) Electrochemical sensor system using a substrate with at least one aperture and method of making the same
KR101357134B1 (ko) 전기화학적 바이오센서, 휴대용 계측기 및 이들을 사용한 혈액시료 중 분석대상물질의 농도 측정방법
US20130084591A1 (en) Analytical test strip with isolated bodily fluid phase-shift and analyte determination sample chambers
JP4184572B2 (ja) バイオセンサ
MX2022015422A (es) Sensor de analitos y metodo para producir un sensor de analitos.
CN102893150A (zh) 具有包括预定尺寸和分布的电化学活性和惰性区域的电极的分析测试条
US8273226B2 (en) Wear-resistant electrochemical test sensor and method of forming the same
DE4132441C2 (de) Dickschicht-Leitfähigkeitselektroden als Biosensor
US20130084590A1 (en) Analytical test strip with bodily fluid phase-shift measurement electrodes
CN204718995U (zh) 检测血液微量信号的生物传感电极
CN206671251U (zh) 一种生物检测试片
KR20120000592A (ko) 전기화학 센서에서의 나선형 전극 구조
JPWO2021259865A5 (es)