CN115836241B - 用于分析扫描功效的方法 - Google Patents

用于分析扫描功效的方法 Download PDF

Info

Publication number
CN115836241B
CN115836241B CN202180041233.4A CN202180041233A CN115836241B CN 115836241 B CN115836241 B CN 115836241B CN 202180041233 A CN202180041233 A CN 202180041233A CN 115836241 B CN115836241 B CN 115836241B
Authority
CN
China
Prior art keywords
focus
image
scan
target
imaging scan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202180041233.4A
Other languages
English (en)
Chinese (zh)
Other versions
CN115836241A (zh
Inventor
马丁·菲利普·古弛
路易丝·乔安妮·科林斯
威廉·海维斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FFEI Ltd
Original Assignee
FFEI Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FFEI Ltd filed Critical FFEI Ltd
Publication of CN115836241A publication Critical patent/CN115836241A/zh
Application granted granted Critical
Publication of CN115836241B publication Critical patent/CN115836241B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/0002Inspection of images, e.g. flaw detection
    • G06T7/0012Biomedical image inspection
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/24Base structure
    • G02B21/241Devices for focusing
    • G02B21/244Devices for focusing using image analysis techniques
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/008Details of detection or image processing, including general computer control
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/36Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365Control or image processing arrangements for digital or video microscopes
    • G02B21/367Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/0002Inspection of images, e.g. flaw detection
    • G06T7/0012Biomedical image inspection
    • G06T7/0014Biomedical image inspection using an image reference approach
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/80Analysis of captured images to determine intrinsic or extrinsic camera parameters, i.e. camera calibration
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10056Microscopic image
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10141Special mode during image acquisition
    • G06T2207/10148Varying focus
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30024Cell structures in vitro; Tissue sections in vitro
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30168Image quality inspection

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Multimedia (AREA)
  • Theoretical Computer Science (AREA)
  • Radiology & Medical Imaging (AREA)
  • Quality & Reliability (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microscoopes, Condenser (AREA)
CN202180041233.4A 2020-06-09 2021-05-26 用于分析扫描功效的方法 Active CN115836241B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2008690.6 2020-06-09
GB2008690.6A GB2595873B (en) 2020-06-09 2020-06-09 A method for analysing scanning efficacy
PCT/GB2021/051271 WO2021250373A1 (en) 2020-06-09 2021-05-26 A method for analysing scanning efficacy

Publications (2)

Publication Number Publication Date
CN115836241A CN115836241A (zh) 2023-03-21
CN115836241B true CN115836241B (zh) 2024-06-25

Family

ID=71616083

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180041233.4A Active CN115836241B (zh) 2020-06-09 2021-05-26 用于分析扫描功效的方法

Country Status (6)

Country Link
US (1) US12422658B2 (https=)
EP (1) EP4107570B1 (https=)
JP (1) JP7655947B2 (https=)
CN (1) CN115836241B (https=)
GB (1) GB2595873B (https=)
WO (1) WO2021250373A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2597502A (en) * 2020-07-24 2022-02-02 Ffei Ltd A whole slide imaging method for a microscope
CN113592800B (zh) * 2021-07-22 2024-06-28 梅卡曼德(北京)机器人科技有限公司 基于动态扫描参数的图像扫描方法及装置
CN118603879A (zh) * 2024-06-24 2024-09-06 飞秒激光研究中心(广州)有限公司 成像辅助装置、生物组织样本的成像方法及激光成像系统

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005119325A2 (en) * 2004-05-27 2005-12-15 Aperio Technologies, Inc. System and method for assessing virtual slide image quality

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7518652B2 (en) * 2000-05-03 2009-04-14 Aperio Technologies, Inc. Method and apparatus for pre-focus in a linear array based slide scanner
US7155049B2 (en) * 2001-01-11 2006-12-26 Trestle Acquisition Corp. System for creating microscopic digital montage images
US7813579B2 (en) * 2004-05-24 2010-10-12 Hamamatsu Photonics K.K. Microscope system
CA2842661C (en) * 2009-10-19 2016-02-23 Ventana Medical Systems, Inc. Imaging system and techniques
GB2505691B (en) 2012-09-07 2018-02-21 Ffei Ltd Method and apparatus for image scanning
JP5941395B2 (ja) * 2012-10-31 2016-06-29 浜松ホトニクス株式会社 画像取得装置及び画像取得装置のフォーカス方法
GB201322188D0 (en) * 2013-12-16 2014-01-29 Ffei Ltd Method and apparatus for estimating an in-focus position
US10482595B2 (en) * 2014-08-27 2019-11-19 S.D. Sight Diagnostics Ltd. System and method for calculating focus variation for a digital microscope
WO2016120441A2 (en) * 2015-01-30 2016-08-04 Ventana Medical Systems, Inc. Quality metrics for automatic evaluation of dual ish images
CN110709749B (zh) 2017-06-09 2021-10-26 电子慕泽雷帕里公司 组合式明视场和相衬显微镜系统及配备其的图像处理设备
WO2019034328A1 (en) * 2017-08-15 2019-02-21 Siemens Healthcare Gmbh IDENTIFYING THE QUALITY OF CELLULAR IMAGES ACQUIRED USING DIGITAL HOLOGRAPHIC MICROSCOPY USING CONVOLUTIONAL NEURAL NETWORKS
CN111183385B (zh) * 2017-09-29 2022-04-08 徕卡生物系统成像股份有限公司 实时自动聚焦扫描
US10861156B2 (en) 2018-02-28 2020-12-08 Case Western Reserve University Quality control for digital pathology slides
CN111007661B (zh) * 2019-12-02 2022-02-22 湖南国科智瞳科技有限公司 一种基于深度学习的显微图像自动聚焦方法及装置

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005119325A2 (en) * 2004-05-27 2005-12-15 Aperio Technologies, Inc. System and method for assessing virtual slide image quality

Also Published As

Publication number Publication date
GB2595873B (en) 2023-01-25
GB2595873A (en) 2021-12-15
GB202008690D0 (en) 2020-07-22
JP2023529083A (ja) 2023-07-07
US20230258919A1 (en) 2023-08-17
JP7655947B2 (ja) 2025-04-02
US12422658B2 (en) 2025-09-23
EP4107570A1 (en) 2022-12-28
EP4107570B1 (en) 2025-03-05
CN115836241A (zh) 2023-03-21
WO2021250373A1 (en) 2021-12-16

Similar Documents

Publication Publication Date Title
US12387328B2 (en) System and method for calculating focus variation for a digital microscope
TWI478101B (zh) 評估影像聚焦品質的方法
US5647025A (en) Automatic focusing of biomedical specimens apparatus
CN102947858B (zh) 包括重叠边缘对比的图像质量评价
US8878923B2 (en) System and method for enhanced predictive autofocusing
CN115836241B (zh) 用于分析扫描功效的方法
JP3822242B2 (ja) スライド及び試料の調製品質を評価するための方法及び装置
KR20140045331A (ko) 현미경 이미징에서의 빠른 오토-포커스
CN113366364A (zh) 载玻片扫描系统中的实时聚焦
US7653260B2 (en) System and method of registering field of view
JP7633373B2 (ja) 顕微鏡のための全スライド撮像方法
WO2025198613A1 (en) Automated focus labeling of histological images for training machine-learning models

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant