CN115771667B - Tumor biomarker detection kit and application method thereof - Google Patents
Tumor biomarker detection kit and application method thereof Download PDFInfo
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- CN115771667B CN115771667B CN202310092928.6A CN202310092928A CN115771667B CN 115771667 B CN115771667 B CN 115771667B CN 202310092928 A CN202310092928 A CN 202310092928A CN 115771667 B CN115771667 B CN 115771667B
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02W—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO WASTEWATER TREATMENT OR WASTE MANAGEMENT
- Y02W90/00—Enabling technologies or technologies with a potential or indirect contribution to greenhouse gas [GHG] emissions mitigation
- Y02W90/10—Bio-packaging, e.g. packing containers made from renewable resources or bio-plastics
Abstract
The invention discloses a tumor biomarker detection kit and a using method thereof, belonging to the technical field of detection kits. The utility model provides a tumour biomarker detect reagent box, includes the box body, and the top activity of box body is provided with the lid, has offered on the box body and has all been provided with the holding tank of opening from top to bottom, lid sliding connection in the holding tank, is provided with the locating component that is used for fixing the box body at the desktop in the holding tank, is provided with a plurality of racks of equidistant range in the box body, has offered the equidistant hole of placing of distributing on every rack, is provided with the reagent pipe in the hole of placing; the invention has simple structure, can automatically arrange the multiple rows of racks into height gradual change distribution when the reagent box is opened, and is convenient for operators to distinguish and take the reagent tubes in the use process; and need not to occupy the usable floor area of more kits, make the kit firmly adsorb on the desktop, reduce the kit by the random touch and follow the risk that the desktop dropped, guarantee the normal detection of kit and use.
Description
Technical Field
The invention relates to the technical field of detection kits, in particular to a tumor biomarker detection kit and a using method thereof.
Background
With the development of tumor cells, certain proteins in tumor patients may change, or new tumor-associated abnormal proteins may be produced. These chemical classes that are responsive to the presence of tumors are collectively referred to as tumor markers. Since tumor markers are not present in normal adult tissues but only in tumor tissues, or the content in the tumor tissues is greatly higher than that in normal tissues, the presence or the amount of the tumor markers can indicate the property of the tumor, and therefore, the detection of abnormal proteins can be used for diagnosing the occurrence of the tumor and monitoring the treatment progress of the tumor by medicaments, thereby playing an important role in diagnosing and treating the tumor.
In the prior art, the invention patent with the patent application number of CN202010838945.6 discloses a tumor marker detection kit, and when the kit is used, the upper cover is turned over, then the side cover is opened, and finally the racks at two sides of the box body are pulled, so that a plurality of racks in the box body are in a straight line, and an operator can conveniently distinguish and take the reagent in the use process. However, in the specific use process of the kit, the operation is complicated, the taking work efficiency of the reagent tube is low, and the sample detection efficiency is reduced; and the upper cover of upset and the rack of arranging into a straight line for the space that the kit occupy on the desktop is great, when the staff was not expected to touch detection kit, knocked over detection kit easily, caused detection kit and reagent tube to drop and damage, thereby can't continue to use, influences the detection progress to tumour marker.
Disclosure of Invention
The invention aims to solve the problems in the prior art, and provides a tumor biomarker detection kit and a using method thereof.
In order to achieve the above purpose, the present invention adopts the following technical scheme:
the utility model provides a tumour biomarker detect reagent box, includes the box body, the top activity of box body is provided with the lid, all be provided with the open-ended holding tank from top to bottom on the box body, lid sliding connection is in the holding tank, be provided with the locating component that is used for fixing the box body at the desktop in the holding tank, be provided with a plurality of racks of equidistance range in the box body, every the hole of placing of equidistance distribution has been seted up on the rack, be provided with the reagent pipe in the hole of placing, the tip lateral wall of reagent pipe is pasted and is stamped the label, be provided with the lifting component that is used for driving the rack and reciprocate in the box body, be provided with the drive assembly who is used for driving the action of lifting component on the box body, drive assembly links to each other with the lid activity.
Preferably, the holding groove is internally provided with a fixed rod, the box cover is provided with a movable cavity matched with the fixed rod, the box cover is provided with a buckle, and one side of the box body away from the fixed rod is provided with a clamping groove matched with the buckle.
Preferably, the lifting assembly comprises threaded rods which are arranged in the box body in a one-to-one correspondence with the placing frames in a rotating mode, each threaded rod is connected with a nut seat in a threaded mode, the nut seats are fixedly connected with the placing frames, and the screw pitches of the spiral lines on the threaded rods are gradually increased from left to right.
Preferably, the drive assembly includes the dwang that rotates the setting on the box body, be provided with drive gear on the dwang, set up flutedly on the lid, be provided with the first rack board of being connected with drive gear meshing in the recess, still be provided with first wind-up roll on the dwang, the winding is connected with first stay cord on the first wind-up roll, the one end that first wind-up roll was kept away from to first stay cord is connected with the second rack board, second rack board sliding connection is in the box body, just be provided with first elastic element between second rack board and the box body inner wall, be provided with the driven gear of being connected with second rack board meshing on the threaded rod.
Preferably, the locating component comprises a movable groove arranged in the accommodating groove, an elastic telescopic rod is arranged on the inner wall of the movable groove, a connecting plate is connected to the bottom of the elastic telescopic rod, the box cover is movably abutted to the top of the connecting plate, and a plurality of sucking disc bodies which are uniformly distributed are arranged at the bottom of the connecting plate.
Preferably, the box body is provided with a positioning block which is movably propped against the box cover in a sliding manner, one end of the positioning block is provided with an extrusion inclined plane, one end of the positioning block, which is far away from the extrusion inclined plane, is connected with a pull plate, two ends of the pull plate are connected with guide rods, the guide rods are slidably connected onto the box body, a fourth elastic element is sleeved outside the guide rods, two ends of the fourth elastic element are respectively connected with the box body and the outer wall of the pull plate, a third pull rope is further arranged on the pull plate, one end of the third pull rope, which is far away from the pull plate, penetrates through the box body and is connected with a lifting piece, and the lifting piece is connected with the sucker body.
Preferably, the cleaning groove is formed in the movable groove, the cleaning seat is arranged in the cleaning groove in a sliding manner, the second winding roller is further arranged on the rotating rod, a second pull rope is wound on the second winding roller, one end, away from the second winding roller, of the second pull rope is connected with the cleaning seat, a second elastic element is sleeved on the outer side of the second pull rope, and two ends of the second elastic element are respectively connected with the cleaning seat and the inner wall of the cleaning groove.
Preferably, the wiping seat comprises a water storage tank which is arranged in the cleaning groove in a sliding manner and is connected with the second pull rope, a connecting pipe is connected to the bottom of the water storage tank, a water outlet which is communicated with the connecting pipe is formed in the bottom of the water storage tank, a working box is connected to the outer side of the connecting pipe in a sliding manner, a third elastic element is sleeved on the outer side of the connecting pipe, two ends of the third elastic element are respectively connected with the bottom wall of the water storage tank and the top wall of the working box, conical plugs for plugging the water outlet are connected in the working box through connecting rods, water leakage holes which are uniformly distributed are formed in the bottom of the working box, wiping cloth is arranged in the bottom of the working box, first inclined planes are formed in two sides of the bottom of the working box, and second inclined planes which are offset with the first inclined planes in a movable manner are formed in two sides of the bottom of the cleaning groove.
Preferably, the bottom of lid is provided with the cushion, the cushion offsets with the activity of reagent pipe's top, be provided with the rubber sleeve in the hole of placing, the reagent pipe is arranged in the rubber sleeve, the bottom of rubber sleeve is provided with first air cavity, the both sides of rubber sleeve are provided with the second air cavity that communicates each other with first air cavity.
The invention also discloses a using method of the tumor biomarker detection kit, which comprises the following steps:
s1: when the kit is used, the buckle on the kit cover is separated from the clamping groove on the kit body, the locking of the kit cover to the kit body is released, then the kit cover is rotated ninety degrees by taking the fixing rod as the center, the kit cover and the accommodating groove are placed in parallel, and then the kit cover is pushed down and moves down in the accommodating groove;
s2: when the box cover moves downwards in the accommodating groove, the first rack plate on the box cover is meshed with the driving gear on the rotating rod to drive the rotating rod to rotate, the first pull rope on the first winding roller is wound when the rotating rod rotates, so that the first pull rope pulls the second rack plate to horizontally slide in the box body, the first elastic element is stretched, the second rack plate is meshed with the driven gears on the plurality of threaded rods when moving, so that the threaded rods rotate, and as the helical line pitches on the plurality of threaded rods gradually become larger from left to right, nut seats on the plurality of threaded rods drive the arranged racks to rise to different heights, and the heights gradually decrease from left to right, so that a worker can quickly search and take out reagent tubes on each row of racks;
s3: when the rotating rod rotates, the second winding roller on the rotating rod synchronously rotates and winds the second pull rope, the second pull rope pulls the water storage tank to move in the cleaning groove, the water storage tank drives the working tank at the bottom to move, the working tank drives the wiping cloth to wipe the tabletop, when the working tank moves rightwards, the working tank is not propped against the bottom inclined surface of the cleaning groove, the working tank is pushed by the elastic force of the third elastic element to move downwards, the working tank drives the conical plug to move downwards, the conical plug is not used for plugging a water outlet at the lower side of the water storage tank, clean water in the water storage tank enters the working tank through the water outlet and the connecting pipe, the wiping cloth is wetted through the water leakage hole at the bottom of the working tank, the cleaning effect of the wiping cloth on the tabletop is ensured, and moisture remains on the wiped tabletop, and when the working tank moves to the right end of the cleaning groove, the inclined surface at the bottom of the working tank is propped against the cleaning groove again, so that the working tank moves upwards and the conical plug plugs the water outlet again;
s4: with the continued downward movement of the box cover, the box cover presses against the connecting plate, the elastic telescopic rod is stretched, the connecting plate drives the sucker body at the bottom side to move downward, the sucker body adheres to the previously wiped tabletop, the box body is fixed on the tabletop, and then a worker detects and analyzes the tumor marker by using the detection reagent in the reagent tube;
s5: after the kit is used, a worker pulls the pull plate to drive the positioning block to move left, the positioning block does not limit the upper side of the box cover, the box cover can be pulled up at the moment, the box cover is buckled on the box body again, in the process of moving left of the pull plate, the pull plate acts on the third pull rope, the third pull rope pulls the pull plate, the pull plate drives one side of the sucker body to tilt, the suction force of the sucker body to the tabletop is relieved, and then the worker places the kit back to the storage place.
Compared with the prior art, the invention provides a tumor biomarker detection kit and a use method thereof, and the kit has the following beneficial effects:
1. according to the tumor biomarker detection kit and the application method thereof, the box cover is turned over, so that the lifting assembly acts, the multiple rows of racks are automatically arranged to be in gradual height change distribution, an operator can conveniently distinguish and take the reagent tube in the use process, the taking and placing efficiency of the reagent tube by the operator is improved, and the detection efficiency of a sample is ensured; and need not to occupy the usable floor area of more kits, make the kit firmly adsorb on the desktop through locating component, reduce the kit by the random risk that touches and drop from the desktop, guarantee the security of the detect reagent in the box body, make the kit can normal measuring use.
2. According to the tumor biomarker detection kit and the application method thereof, when the box cover moves downwards in the accommodating groove, the first rack plate on the box cover is meshed with the driving gear on the rotating rod to drive the rotating rod to rotate, the first pull rope on the first winding roller is wound up when the rotating rod rotates, the first pull rope pulls the second rack plate to horizontally slide in the box body, the first elastic element is stretched, the second rack plate is meshed with the driven gears on the plurality of threaded rods when moving, the threaded rods rotate, and the helical line pitch on the plurality of threaded rods gradually increases from left to right, so that the nut seats on the plurality of threaded rods drive the arranged and distributed racks to rise to different heights, the heights gradually decrease from left to right, and a worker can quickly search and take out reagent tubes on each row of racks, so that the working efficiency of the worker is improved.
3. According to the tumor biomarker detection kit and the application method thereof, when the rotating rod rotates, the second winding roller on the rotating rod synchronously rotates and winds the second pull rope, the second pull rope pulls the water storage tank to move in the cleaning groove, the water storage tank drives the working box at the bottom to move, the working box drives the wiping cloth to wipe the tabletop, when the working box moves rightwards, the working box does not prop against the bottom inclined surface of the cleaning groove, the working box moves downwards under the pushing of the elastic force of the third elastic element, the conical plug does not plug the water outlet at the lower side of the water storage tank, clear water in the water storage tank enters the working box through the water outlet and the connecting pipe, the wiping cloth is wetted through the water leakage hole at the bottom of the working box, the cleaning effect of the wiping cloth on the tabletop is guaranteed, and after the sucker is stained with water, the air in the sucker can be cleaner, the pressure in the sucker is smaller, the outside atmospheric pressure can press the sucker to be tighter, the fixing effect of the body on the box body and the tabletop is improved, and the safety of the detection reagent in the box is guaranteed.
4. According to the tumor biomarker detection kit and the application method thereof, the pulling plate is pulled to drive the positioning block to move left, the positioning block does not limit the upper side of the box cover, the box cover can be pulled up at the moment, the box cover is buckled on the box body again, in the process of moving left of the pulling plate, the pulling plate acts on the third pull rope, the third pull rope pulls the lifting piece, the lifting piece drives one side of the sucker body to tilt, the suction force of the sucker body to the tabletop is relieved, the fixation of the box body is relieved quickly by workers, and the working efficiency of the workers is improved.
5. According to the tumor biomarker detection kit and the application method thereof, the rubber sleeve is arranged in the placement hole, when the box cover is closed on the upper side of the box body, the rubber pad on the box cover presses down the reagent tube in the placement hole, so that the reagent tube is effectively fixed in the box body, the reagent tube is prevented from shaking up and down in the box body to collide, the reagent tube is broken, the reagent tube is extruded by the rubber pad at the bottom of the box cover and moves down, the reagent tube generates pressure on the first air cavity at the bottom of the rubber sleeve, air in the first air cavity is extruded into the second air cavity, the second air cavity expands and effectively clamps the reagent tube, the reagent tube is prevented from shaking when being stored or carried, after the box cover is opened, the upper side of the reagent tube is not stressed any more, the reagent tube is prevented from shaking up and down the pressure of the first air cavity at the bottom of the rubber sleeve, the second air cavity is not expanded to clamp the side of the reagent tube, the force spent by operators is reduced, and the labor intensity and the operation difficulty of the operators are reduced.
Drawings
FIG. 1 is a schematic diagram of a first embodiment of the present invention;
FIG. 2 is a schematic diagram of a second embodiment of the present invention;
FIG. 3 is a schematic cross-sectional view of the present invention;
FIG. 4 is a partially enlarged schematic illustration of the structure of portion A of FIG. 3 in accordance with the present invention;
FIG. 5 is a schematic diagram of a cross-sectional structure of the present invention;
FIG. 6 is a partially enlarged schematic illustration of the structure of portion B of FIG. 5 in accordance with the present invention;
FIG. 7 is a schematic view of a rack according to the present invention;
FIG. 8 is a second schematic structural view of the rack of the present invention;
FIG. 9 is a schematic cross-sectional view of a cap according to the present invention;
FIG. 10 is a schematic view of the external structure of the rotating lever of the present invention;
FIG. 11 is a schematic cross-sectional view of a wiper seat according to the present invention;
FIG. 12 is a schematic view of the external structure of the pulling plate of the present invention;
fig. 13 is a schematic cross-sectional view of a rack according to the present invention.
In the figure: 1. a case body; 101. a receiving groove; 1011. a fixed rod; 102. a clamping groove; 2. a box cover; 201. a movable cavity; 202. a buckle; 203. a first rack plate; 204. rubber cushion; 3. a placing rack; 301. placing the hole; 4. a reagent tube; 401. a label; 5. a threaded rod; 501. a nut seat; 502. a driven gear; 6. a rotating lever; 601. a drive gear; 602. a first wind-up roll; 6021. a first pull rope; 603. a second wind-up roll; 6031. a second pull rope; 7. a second rack plate; 701. a first elastic element; 8. a movable groove; 801. an elastic telescopic rod; 802. a connecting plate; 9. a suction cup body; 901. lifting the pull tab; 10. cleaning the groove; 11. a wiping seat; 111. a water storage tank; 1111. a water outlet; 112. a connecting pipe; 113. a working box; 1131. a conical plug; 1132. a water leakage hole; 114. a third elastic element; 115. wiping cloth; 12. a second elastic element; 13. pulling a plate; 131. a positioning block; 132. a guide rod; 133. a fourth elastic element; 134. a third pull rope; 14. a rubber sleeve; 141. a first air chamber; 142. and a second air cavity.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments.
In the description of the present invention, it should be understood that the terms "upper," "lower," "front," "rear," "left," "right," "top," "bottom," "inner," "outer," and the like indicate or are based on the orientation or positional relationship shown in the drawings, merely to facilitate description of the present invention and to simplify the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present invention.
Example 1
Referring to fig. 1, fig. 2, fig. 3, fig. 5, fig. 7, fig. 8, fig. 9 and fig. 13, a tumor biomarker detection kit comprises a box body 1, the top activity of box body 1 is provided with lid 2, all be provided with open-ended holding tank 101 from top to bottom on the box body 1, lid 2 sliding connection is provided with the locating component that is used for fixing box body 1 at the desktop in holding tank 101, be provided with a plurality of racks 3 of equidistant range in the box body 1, set up equidistant placement hole 301 that distributes on every rack 3, be provided with reagent pipe 4 in the placement hole 301, the tip lateral wall of reagent pipe 4 is pasted and is stamped label 401, be provided with the lifting component that is used for driving rack 3 up-and-down displacement in the box body 1, be provided with the drive assembly who is used for driving lifting component action on the box body 1, drive assembly links to each other with lid 2 activity.
Further, a fixed rod 1011 is fixed in the accommodating groove 101, a movable cavity 201 matched with the fixed rod 1011 is formed in the box cover 2, a buckle 202 is arranged on the box cover 2, and a clamping groove 102 matched with the buckle 202 is formed in one side, away from the fixed rod 1011, of the box body 1.
Specifically, when the kit is used, the buckle 202 on the box cover 2 is separated from the clamping groove 102 on the box body 1, the locking of the box cover 2 to the box body 1 is released, then the box cover 2 rotates ninety degrees around the fixed rod 1011 to enable the box cover 2 to be placed in parallel with the accommodating groove 101, then the box cover 2 is pushed down, the box cover 2 moves down in the accommodating groove 101, and the driving component acts and drives the lifting component to work; the invention is simple to operate, the multiple rows of the placing frames 3 can be automatically arranged into the height gradual change distribution by only turning the box cover 2, each row of the reagent tubes 4 is distributed along with the height gradual change of the placing frames 3, and the labels 401 on each reagent tube 4 fill in the names of different detection reagents, so that an operator can conveniently distinguish and take the reagent tubes 4 in the use process, the taking and placing efficiency of the operator on the reagent tubes 4 is improved, and the detection efficiency of samples is further ensured; and need not to occupy the usable floor area of more kits, move down in holding tank 101 along with lid 2, and locating component moves down and fixes box body 1 on the desktop, reduces the kit by the random risk that touches and drop from the desktop, guarantees the normal detection use of kit, guarantees the security of the detect reagent in the box body 1.
Example 2
Referring to fig. 3, 4, 5, 6, 7, 8, 9 and 10, on the basis of embodiment 1, a tumor biomarker detection kit further includes a lifting assembly including threaded rods 5 rotatably disposed in the box body 1 and in one-to-one correspondence with the placement frames 3, each threaded rod 5 is screwed with a nut seat 501, the nut seat 501 is fixedly connected with the placement frame 3, and the helical pitches on the plurality of threaded rods 5 gradually increase from left to right.
Further, the driving assembly comprises a rotating rod 6 which is rotatably arranged on the box body 1, a driving gear 601 is arranged on the rotating rod 6, a groove is formed in the box cover 2, a first rack plate 203 which is meshed and connected with the driving gear 601 is arranged in the groove, a first winding roller 602 is further arranged on the rotating rod 6, a first pull rope 6021 is wound and connected on the first winding roller 602, one end, far away from the first winding roller 602, of the first pull rope 6021 is connected with a second rack plate 7, the second rack plate 7 is slidably connected in the box body 1, a first elastic element 701 is arranged between the second rack plate 7 and the inner wall of the box body 1, and a driven gear 502 which is meshed and connected with the second rack plate 7 is arranged on the threaded rod 5.
Specifically, when the box cover 2 moves down in the accommodating groove 101, the first rack plate 203 on the box cover 2 is in meshing transmission with the driving gear 601 on the rotating rod 6, the driving gear 601 drives the rotating rod 6 to rotate, the first pull rope 6021 on the first winding roller 602 is wound up when the rotating rod 6 rotates, the first pull rope 6021 pulls the second rack plate 7 to horizontally slide in the box body 1, the first elastic element 701 is stretched, the second rack plate 7 is meshed with the driven gears 502 on the plurality of threaded rods 5 when moving, the threaded rods 5 are rotated, and the screw pitches of the spiral lines on the plurality of threaded rods 5 gradually become larger from left to right, so that the nut seats 501 on the plurality of threaded rods 5 drive the arranged placing racks 3 to rise to different heights, the heights gradually decrease from left to right, a worker can quickly search and take out the reagent tubes 4 on each row of the placing racks 3, more using areas of the reagent boxes are not required to occupy, the risk that the reagent boxes are touched and fall on the ground when being used is reduced, and the safety of the detection reagent in the box body 1 is ensured.
Example 3
Referring to fig. 3, 5 and 6, on the basis of embodiment 2, further, the positioning assembly includes a movable slot 8 provided in the accommodating slot 101, an elastic telescopic rod 801 is provided on the inner wall of the movable slot 8, the bottom of the elastic telescopic rod 801 is connected with a connecting plate 802, the box cover 2 is movably abutted against the top of the connecting plate 802, and a plurality of sucking disc bodies 9 which are uniformly distributed are provided at the bottom of the connecting plate 802.
Specifically, as the box cover 2 moves down continuously, the box cover 2 presses against the connecting plate 802, the elastic telescopic rod 801 is stretched, the connecting plate 802 drives the sucker body 9 at the bottom side to move down, the sucker body 9 adheres to the table top, the box body 1 is fixed on the table top, a worker detects and analyzes the tumor marker by using the detection reagent in the reagent tube 4, the reagent box is firmly adsorbed on the table top, the risk that the reagent box falls off from the table top due to random touching is reduced, and normal detection and use of the reagent box are ensured.
Example 4
Referring to fig. 1, fig. 2, fig. 3, fig. 4, fig. 5, fig. 6 and fig. 12, on the basis of embodiment 3, further, a positioning block 131 which is movably abutted against the box cover 2 is slidably connected on the box body 1, one end of the positioning block 131 is provided with an extrusion inclined plane, one end of the positioning block 131 far away from the extrusion inclined plane is connected with a pull plate 13, both ends of the pull plate 13 are connected with a guide rod 132, the guide rod 132 is slidably connected on the box body 1, a fourth elastic element 133 is sleeved outside the guide rod 132, both ends of the fourth elastic element 133 are respectively connected with the outer walls of the box body 1 and the pull plate 13, a third pull rope 134 is further arranged on the pull plate 13, one end of the third pull rope 134 far away from the pull plate 13 penetrates through the box body 1 and is connected with a pull plate 901, and the pull plate 901 is connected with the sucker body 9.
Specifically, after the detection kit is used, a worker pulls the pull plate 13 to enable the pull plate 13 to drive the positioning block 131 to move left, the guide rod 132 slides in the box body 1, the fourth elastic element 133 is stretched, the positioning block 131 does not limit the upper side of the box cover 2, the box cover 2 can be pulled up at the moment, the box cover 2 is buckled on the box body 1 again, in the process of moving the pull plate 13 left, the pull plate 13 applies force to the third pull rope 134, the third pull rope 134 pulls the pull plate 901, the pull plate 901 drives one side of the sucker body 9 to tilt, the suction force of the sucker body 9 to a table top is relieved, and then the worker places the kit back to a storage place; it should be noted that, the actual length of the third pull cord 134 should be greater than the distance from the pull plate 13 to the pull tab 901 on the outer side of the sucker body 9, and a redundant distance is reserved, so that the sucker body 9 can move up and down along with the connecting plate 802 when the box cover 2 is pressed down, and the third pull cord 134 is prevented from being too short, so that when the sucker body 9 moves down, the pull tab 901 on one side of the sucker body 9 is pulled by the third pull cord 134, and the sucker body 9 cannot be attached to the desktop.
Example 5
Referring to fig. 3, fig. 5, fig. 6, fig. 9 and fig. 10, based on embodiment 4, further, a cleaning groove 10 is provided in the movable groove 8, a wiping seat 11 is slidably provided in the cleaning groove 10, a second winding roller 603 is further provided on the rotating rod 6, a second pull rope 6031 is wound on the second winding roller 603, one end of the second pull rope 6031 far away from the second winding roller 603 is connected with the wiping seat 11, a second elastic element 12 is sleeved outside the second pull rope 6031, and two ends of the second elastic element 12 are respectively connected with the wiping seat 11 and the inner wall of the cleaning groove 10.
Further, the wiping seat 11 comprises a water storage tank 111 which is arranged in the cleaning groove 10 in a sliding manner and is connected with the second pull rope 6031, a connecting pipe 112 is connected to the bottom of the water storage tank 111, a water outlet 1111 which is communicated with the connecting pipe 112 is formed in the bottom of the water storage tank 111, a working box 113 is connected to the outer side of the connecting pipe 112 in a sliding manner, a third elastic element 114 is sleeved on the outer side of the connecting pipe 112, two ends of the third elastic element 114 are respectively connected with the bottom wall of the water storage tank 111 and the top wall of the working box 113, a conical plug 1131 for blocking the water outlet 1111 is connected in the working box 113 through a connecting rod, water leakage holes 1132 which are uniformly distributed are formed in the bottom of the working box 113, wiping cloth 115 is arranged at the bottom of the working box 113, two sides of the bottom of the working box 113 are respectively set to be first inclined surfaces, and two sides of the bottom of the cleaning groove 10 are respectively set to be second inclined surfaces which are movably abutted to the first inclined surfaces.
Specifically, when the box cover 2 moves downwards in the accommodating groove 101, the first rack plate 203 on the box cover 2 is meshed with the driving gear 601 on the rotating rod 6 to drive the rotating rod 6 to rotate, the second winding roller 603 on the rotating rod 6 synchronously rotates and winds the second pull rope 6031, the second pull rope 6031 pulls the water storage tank 111 to move in the cleaning groove 10, the water storage tank 111 drives the bottom working box 113 to move, the working box 113 drives the wiping cloth 115 to wipe the tabletop, and when the working box 113 moves rightwards, the working box 113 does not abut against the bottom inclined surface of the cleaning groove 10 any more, the working box 113 moves downwards under the pushing of the elastic force of the third elastic element 114, the working box 113 drives the conical plug 1131 to move downwards, the conical plug 1131 does not block the water outlet 1111 at the lower side of the water storage tank 111, clean water in the water storage tank 111 enters the working box 113 through the water outlet 1111 and the connecting pipe 112, and moisten the wiping cloth 115 through the water leakage hole 1132 at the bottom of the working box 113, guarantee the cleaning effect of the wiping cloth 115 on the tabletop, and the water is remained on the tabletop after wiping, when the working box 113 moves to the right end of the cleaning tank 10, the inclined surface at the bottom of the working box 113 is propped against the cleaning tank 10 again, so that the working box 113 moves upwards and the conical plug 1131 plugs the water outlet 1111 again, then the sucker body 9 moves downwards to attach the tabletop after wiping, after the sucker is smeared with the water remained on the tabletop, the air in the sucker can be discharged more cleanly, the pressure in the sucker is enabled to be smaller, the external atmospheric pressure can press the sucker more tightly, the fixing effect of the sucker body 9 on the box body 1 and the tabletop is improved, the risk that the kit is touched randomly and falls from the tabletop is reduced, and the normal detection and use of the kit are guaranteed.
Example 6
Referring to fig. 13, a tumor biomarker detection kit is further provided, based on embodiment 1, with a rubber pad 204 at the bottom of the box cover 2, the rubber pad 204 is movably abutted against the top of the reagent tube 4, a rubber sleeve 14 is disposed in the placement hole 301, the reagent tube 4 is disposed in the rubber sleeve 14, a first air cavity 141 is disposed at the bottom of the rubber sleeve 14, and second air cavities 142 mutually communicated with the first air cavity 141 are disposed at two sides of the rubber sleeve 14.
Specifically, by arranging the rubber pad 204 at the bottom side of the box cover 2, when the box cover 2 is closed at the upper side of the box body 1, the rubber pad 204 on the box cover 2 presses down the reagent tube 4 in the placement hole 301, so that the reagent tube 4 is effectively fixed in the box body 1, the reagent tube 4 is prevented from being broken due to shaking and collision in the box body 1 when the reagent tube 4 moves along with the box body 1, the rubber sleeve 14 is arranged in the placement hole 301, the reagent tube 4 is prevented from being collided with the placement frame 3 when being placed, and the service life of the reagent tube 4 is prolonged; and reagent pipe 4 receives the cushion 204 extrusion back of lid 2 bottom to move down, reagent pipe 4 produces pressure to the first air cavity 141 of rubber sleeve 14 bottom, the air in the first air cavity 141 is pressed and is got into second air cavity 142, the effective centre gripping of second air cavity 142 inflation and to reagent pipe 4, rock when preventing reagent pipe 4 to deposit or carry, when using the kit, lid 2 is opened the back, reagent pipe 4 upside no longer atress, reagent pipe 4 diminishes the pressure to the first air cavity 141 of rubber sleeve 14 bottom side, the second air cavity 142 no longer expands to reagent pipe 4 side centre gripping, reduce the force that operating personnel pulled reagent pipe 4 and spent, reduce operating personnel's intensity of labour and the operation degree of difficulty.
The invention also discloses a using method of the tumor biomarker detection kit, which comprises the following steps:
s1: when the kit is used, the buckle 202 on the box cover 2 is separated from the clamping groove 102 on the box body 1, the locking of the box cover 2 to the box body 1 is released, then the box cover 2 rotates ninety degrees by taking the fixed rod 1011 as the center, the box cover 2 and the accommodating groove 101 are placed in parallel, then the box cover 2 is pushed down, and the box cover 2 moves down in the accommodating groove 101;
s2: when the box cover 2 moves downwards in the accommodating groove 101, the first rack plate 203 on the box cover 2 is meshed with the driving gear 601 on the rotating rod 6 for transmission, the driving gear 601 drives the rotating rod 6 to rotate, the first pull rope 6021 on the first winding roller 602 is wound when the rotating rod 6 rotates, the first pull rope 6021 pulls the second rack plate 7 to horizontally slide in the box body 1, the first elastic element 701 is stretched, the second rack plate 7 is meshed with the driven gears 502 on the plurality of threaded rods 5 when moving, the threaded rods 5 rotate, and the spiral thread pitch on the plurality of threaded rods 5 gradually increases from left to right, so that the nut seats 501 on the plurality of threaded rods 5 drive the placing racks 3 which are distributed in an arrangement mode to rise to different heights, the heights gradually decrease from left to right, and a worker can quickly search and take out the reagent tubes 4 on each row of the placing racks 3;
s3: when the rotating rod 6 rotates, the second winding roller 603 on the rotating rod 6 synchronously rotates and winds the second pull rope 6031, the second pull rope 6031 pulls the water storage tank 111 to move in the cleaning groove 10, the water storage tank 111 drives the bottom working box 113 to move, the working box 113 drives the wiping cloth 115 to wipe a tabletop, when the working box 113 moves rightwards, the working box 113 does not abut against the bottom inclined surface of the cleaning groove 10 any more, the working box 113 moves downwards under the pushing of the elastic force of the third elastic element 114, the working box 113 drives the conical plug 1131 to move downwards, the conical plug 1131 does not plug the water outlet 1111 at the lower side of the water storage tank 111, clear water in the water storage tank 111 enters the working box 113 through the water outlet 1111 and the connecting pipe 112, wets the wiping cloth 115 through the water leakage hole 1132 at the bottom of the working box 113, the cleaning effect of the wiping cloth 115 is guaranteed, and moisture remains on the wiped tabletop, when the working box 113 moves to the right end of the cleaning groove 10, the inclined surface at the bottom of the working box 113 again abuts against the cleaning groove 10, the working box 113 moves upwards and the conical plug 1131 again plugs the water outlet 1111;
s4: as the box cover 2 moves downwards, the box cover 2 presses against the connecting plate 802, the elastic telescopic rod 801 is stretched, the connecting plate 802 drives the sucker body 9 at the bottom side to move downwards, the sucker body 9 adheres to the previously wiped tabletop, the box body 1 is fixed on the tabletop, and then a worker detects and analyzes the tumor marker by using the detection reagent in the reagent tube 4;
s5: after the kit is used, a worker pulls the pull plate 13 to enable the pull plate 13 to drive the positioning block 131 to move left, the positioning block 131 does not limit the upper side of the box cover 2, the box cover 2 can be pulled up at the moment, the box cover 2 is buckled on the box body 1 again, and in the process of moving the pull plate 13 left, the pull plate 13 acts on the third pull rope 134, the third pull rope 134 pulls the pull plate 901, the pull plate 901 drives one side of the sucker body 9 to tilt, the suction force of the sucker body 9 to a tabletop is relieved, and then the worker places the kit back to a storage place.
The foregoing is only a preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art, who is within the scope of the present invention, should make equivalent substitutions or modifications according to the technical scheme of the present invention and the inventive concept thereof, and should be covered by the scope of the present invention.
Claims (5)
1. The utility model provides a tumor biomarker detect reagent box, includes box body (1), its characterized in that, the top activity of box body (1) is provided with lid (2), all be provided with open-ended holding tank (101) from top to bottom on box body (1), lid (2) sliding connection is in holding tank (101), be provided with in holding tank (101) and be used for fixing box body (1) at the locating component of desktop, be provided with a plurality of racks (3) of equidistant range in box body (1), every set up equidistant placement hole (301) of distributing on rack (3), be provided with reagent pipe (4) in placement hole (301), label (401) are pasted to the tip lateral wall of reagent pipe (4), be provided with the lifting component that is used for driving lifting component action in box body (1), be provided with the drive component and link to each other with lid (2) activity on box body (1);
a fixed rod (1011) is fixedly arranged in the accommodating groove (101), a movable cavity (201) matched with the fixed rod (1011) is formed in the box cover (2), a buckle (202) is arranged on the box cover (2), and a clamping groove (102) matched with the buckle (202) is formed in one side, away from the fixed rod (1011), of the box body (1);
the lifting assembly comprises threaded rods (5) which are rotatably arranged in the box body (1) and correspond to the placing frames (3) one by one, each threaded rod (5) is connected with a nut seat (501) in a threaded manner, the nut seats (501) are fixedly connected with the placing frames (3), and the screw pitches of spiral lines on the plurality of threaded rods (5) are gradually increased from left to right;
the driving assembly comprises a rotating rod (6) which is rotatably arranged on the box body (1), a driving gear (601) is arranged on the rotating rod (6), a groove is formed in the box cover (2), a first rack plate (203) which is in meshed connection with the driving gear (601) is arranged in the groove, a first winding roller (602) is further arranged on the rotating rod (6), a first pull rope (6021) is wound on the first winding roller (602), one end, far away from the first winding roller (602), of the first pull rope (6021) is connected with a second rack plate (7), the second rack plate (7) is slidably connected in the box body (1), a first elastic element (701) is arranged between the second rack plate (7) and the inner wall of the box body (1), and a driven gear (502) which is in meshed connection with the second rack plate (7) is arranged on the threaded rod (5);
the positioning assembly comprises a movable groove (8) arranged in the accommodating groove (101), an elastic telescopic rod (801) is arranged on the inner wall of the movable groove (8), a connecting plate (802) is connected to the bottom of the elastic telescopic rod (801), the box cover (2) is movably abutted to the top of the connecting plate (802), and a plurality of sucking disc bodies (9) which are uniformly distributed are arranged at the bottom of the connecting plate (802);
the novel box comprises a box body (1), wherein a positioning block (131) which is movably propped against a box cover (2) is slidably connected onto the box body (1), an extrusion inclined plane is arranged at one end of the positioning block (131), one end of the positioning block (131) away from the extrusion inclined plane is connected with a pull plate (13), guide rods (132) are connected to two ends of the pull plate (13) in a sliding mode, a fourth elastic element (133) is sleeved outside the guide rods (132), two ends of the fourth elastic element (133) are respectively connected with the outer walls of the box body (1) and the pull plate (13), a third pull rope (134) is further arranged on the pull plate (13), one end of the third pull rope (134) away from the pull plate (13) penetrates through the box body (1) and is connected with a lifting piece (901), and the lifting piece (901) is connected with a sucker body (9).
2. The tumor biomarker detection kit according to claim 1, wherein a cleaning groove (10) is formed in the movable groove (8), a wiping seat (11) is arranged in the cleaning groove (10) in a sliding manner, a second winding roller (603) is further arranged on the rotating rod (6), a second pull rope (6031) is wound on the second winding roller (603), one end, far away from the second winding roller (603), of the second pull rope (6031) is connected with the wiping seat (11), a second elastic element (12) is sleeved on the outer side of the second pull rope (6031), and two ends of the second elastic element (12) are respectively connected with the wiping seat (11) and the inner wall of the cleaning groove (10).
3. The tumor biomarker detection kit according to claim 2, wherein the wiping seat (11) comprises a water storage tank (111) which is slidably arranged in the cleaning groove (10) and connected with the second pull rope (6031), a connecting pipe (112) is connected to the bottom of the water storage tank (111), a water outlet (1111) which is communicated with the connecting pipe (112) is formed in the bottom of the water storage tank (111), a working box (113) is slidably connected to the outer side of the connecting pipe (112), a third elastic element (114) is sleeved on the outer side of the connecting pipe (112), two ends of the third elastic element (114) are respectively connected with the bottom wall of the water storage tank (111) and the top wall of the working box (113), a conical plug (1131) for blocking the water outlet (1111) is connected in the working box (113) through a connecting rod, water leakage holes (1132) which are uniformly distributed are formed in the bottom of the working box (113), wiping cloths (115) are arranged at the bottom two sides of the working box (113) are respectively arranged to be a first inclined plane, and the two sides of the bottom of the working box (113) are respectively arranged to be offset to the second inclined plane of the cleaning groove (10).
4. The tumor biomarker detection kit according to claim 1, wherein a rubber pad (204) is arranged at the bottom of the box cover (2), the rubber pad (204) is movably propped against the top of the reagent tube (4), a rubber sleeve (14) is arranged in the placement hole (301), the reagent tube (4) is arranged in the rubber sleeve (14), a first air cavity (141) is arranged at the bottom of the rubber sleeve (14), and second air cavities (142) which are mutually communicated with the first air cavity (141) are arranged at two sides of the rubber sleeve (14).
5. A method of using the tumor biomarker detection kit according to any of claims 1 to 4, further comprising the steps of:
s1: when the kit is used, the clamping buckle (202) on the box cover (2) is separated from the clamping groove (102) on the box body (1), the locking of the box cover (2) on the box body (1) is released, then the box cover (2) rotates ninety degrees by taking the fixed rod (1011) as the center, the box cover (2) and the accommodating groove (101) are placed in parallel, then the box cover (2) is pushed down, and the box cover (2) moves down in the accommodating groove (101);
s2: when the box cover (2) moves downwards in the accommodating groove (101), the first rack plate (203) on the box cover (2) is meshed with the driving gear (601) on the rotating rod (6), the driving gear (601) drives the rotating rod (6) to rotate, the first pull rope (6021) on the first winding roller (602) is wound when the rotating rod (6) rotates, the first pull rope (6021) pulls the second rack plate (7) to slide horizontally in the box body (1), the first elastic element (701) is stretched, the second rack plate (7) is meshed with the driven gears (502) on the plurality of threaded rods (5) when moving, the threaded rods (5) are rotated, and as the spiral thread pitches on the plurality of threaded rods (5) are gradually increased from left to right, nut seats (501) on the plurality of threaded rods (5) drive the arranged placing racks (3) to rise to different heights, the heights gradually decrease from left to right, and workers can quickly search for the reagent tubes (4) on each row of placing racks (3) and take out the reagent tubes;
s3: and when the rotating rod (6) rotates, the second winding roller (603) on the rotating rod (6) synchronously rotates and winds the second pull rope (6031), the second pull rope (6031) pulls the water storage tank (111) to move in the cleaning tank (10), the water storage tank (111) drives the working box (113) at the bottom to move, the working box (113) drives the wiping cloth (115) to wipe the tabletop, when the working box (113) moves rightwards, the working box (113) is not abutted against the bottom inclined surface of the cleaning tank (10) any more, the working box (113) moves downwards under the pushing of the elastic force of the third elastic element (114), the working box (113) drives the conical plug (1131) to move downwards, the conical plug (1131) does not block the water outlet (1111) at the lower side of the water storage tank (111), the water storage tank (111) enters the working box (113) through the water outlet (1111) and the connecting pipe (112), the water leakage hole (1132) at the bottom of the working box (113) wets the wiping cloth (115) to ensure that the wiping cloth (115) is abutted against the bottom inclined surface of the cleaning tank (10) when the cleaning tank (113) is moved rightwards, and the water remains on the tabletop (10) to the bottom inclined surface (10), moving up the working box (113) and enabling the conical plug (1131) to plug the water outlet (1111) again;
s4: with the continued downward movement of the box cover (2), the box cover (2) presses against the connecting plate (802), the elastic telescopic rod (801) is stretched, the connecting plate (802) drives the sucker body (9) at the bottom side to move downward, the sucker body (9) adheres to the previously wiped tabletop, the box body (1) is fixed on the tabletop, and then a worker detects and analyzes the tumor marker by using the detection reagent in the reagent tube (4);
s5: after the kit is used, a worker pulls the pull plate (13) to enable the pull plate (13) to drive the positioning block (131) to move left, the positioning block (131) is not limited to the upper side of the box cover (2), the box cover (2) can be pulled up at the moment, the box cover (2) is buckled on the box body (1) again, in the process that the pull plate (13) moves left, the pull plate (13) acts on the third pull rope (134), the third pull rope (134) pulls the pull plate (901), the pull plate (901) drives one side of the sucker body (9) to tilt, the suction force of the sucker body (9) on the table top is relieved, and then the worker places the kit back to a storage place.
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| CN202310092928.6A CN115771667B (en) | 2023-02-10 | 2023-02-10 | Tumor biomarker detection kit and application method thereof |
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| CN202310092928.6A CN115771667B (en) | 2023-02-10 | 2023-02-10 | Tumor biomarker detection kit and application method thereof |
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| CN116477197B (en) * | 2023-04-03 | 2023-11-21 | 杭州萧山华谱医学检验实验室有限公司 | High-stability detection kit for collecting and detecting blood plasma A beta-42 |
| CN116539362B (en) * | 2023-05-13 | 2023-11-03 | 杭州古伽船舶科技有限公司 | Sampling ship automatic sampling system based on Internet of things |
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