CN111896739B - Tumor marker detection kit - Google Patents
Tumor marker detection kit Download PDFInfo
- Publication number
- CN111896739B CN111896739B CN202010838945.6A CN202010838945A CN111896739B CN 111896739 B CN111896739 B CN 111896739B CN 202010838945 A CN202010838945 A CN 202010838945A CN 111896739 B CN111896739 B CN 111896739B
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- box body
- locking
- cavity
- upper cover
- rod
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
Abstract
The invention belongs to the technical field of medical instruments, and particularly relates to a tumor marker detection kit which comprises a kit body, wherein an upper cover is rotatably arranged above the kit body and can rotate within a range of 180 degrees; a placing frame is arranged in the box body; the placing rack is provided with a storage hole; the placing racks in the box body are sequentially connected together from left to right end to end through the hinge blocks; the hinged blocks hinged by the rotating connecting shafts at the two ends of the upper surface of the placing rack are respectively positioned at the two sides of the placing rack; a connecting block is arranged in the box body and positioned at the center line of the box body in the length direction; the connecting block is fixedly connected with a hinge block positioned in the middle of the box body; the side surfaces of the left side and the right side of the box body are provided with mutually symmetrical pull-out ports; a side cover is rotatably arranged at the pull-out opening of the box body, and the side plate can rotate within a range of 90 degrees; the invention has simple structure, can simultaneously place a plurality of detection reagents and can realize the quick search of the reagents.
Description
Technical Field
The invention belongs to the technical field of medical instruments, and particularly relates to a tumor marker detection kit.
Background
Tumor marker detect reagent box is the box that holds the required chemical reagent of detection tumour, because the required reagent kind and the quantity that uses of tumour detection are more, and in order to guarantee the stability that the kit was placed moreover, often set up reagent according to the multirow in the current reagent box, however this has just produced a problem, that is just inconvenient to the seeking of reagent.
The prior art also has some technical schemes, such as chinese patent with application number CN201922292363.8, including a box body, a detection strip, a tube clamp and a support foot stool, the front side of the top of the box body is provided with a groove, the rear side of the top of the box body is fixedly provided with a reagent bottle, the right side of the top surface of the box body is fixedly provided with a colorimetric card, the inner cavity of the groove is provided with the detection strip, the left side of the top of the detection strip is fixedly provided with a water absorption filter section, the middle of the top of the detection strip is fixedly provided with a nitrocellulose section, the right side of the top of the detection strip is fixedly provided with a specific antigen section, the right side of the box body is fixedly provided with the tube clamp, the tube clamp is provided with a dropper, in the scheme, various detection reagents can be stored in the kit at one time, but in the using process, the reagents in the kit, the search for of reagent is inconvenient, simultaneously, in the use, the reagent box is not good to the fixed effect with the device that holds reagent in this scheme, leads to detect reagent to leak easily.
Disclosure of Invention
The invention provides a tumor marker detection kit, aiming at making up for the defects of the prior art and solving the problem that operators cannot conveniently search for reagents in the kit when the existing detection kit is used.
The technical scheme adopted by the invention for solving the technical problems is as follows: the tumor marker detection kit comprises a kit body, wherein an upper cover is arranged above the kit body; the upper cover is provided with a first rotating shaft; the upper end of the box body is provided with a rotating seat; the rotating shaft is rotatably arranged in the rotating seat; the upper cover rotates within a range of 180 degrees along the first rotating shaft; a placing frame is arranged in the box body; the plurality of placing frames are uniformly placed in the box body; the placing rack is provided with a storage hole; a test tube for containing a detection reagent is placed in the storage hole; the appearance of the placing rack is cuboid; the length direction of the placing frame is vertical to the length direction of a rotating shaft on the upper cover; two ends of the upper surface of the placing frame are provided with rotating connecting shafts; the placing racks in the box body are sequentially connected together from left to right end to end through the hinge blocks; the rotating connecting shafts on the same side of two adjacent placing racks are respectively hinged to two ends of the hinge block, and the rotating connecting shafts can rotate freely; the hinged blocks hinged by the rotating connecting shafts at the two ends of the upper surface of the placing rack are respectively positioned at the two sides of the placing rack; a connecting block is arranged in the box body and positioned at the center line of the box body in the length direction; the connecting block is positioned on the side surface far away from the rotating seat in the box body, and the connecting block is fixedly connected with the box body; the connecting block is fixedly connected with a hinge block positioned in the middle of the box body; the side surfaces of the left side and the right side of the box body are provided with mutually symmetrical pull-out ports; a side cover is arranged at the pull-out opening of the box body; a second rotating shaft is arranged on the side cover; the second rotating shaft is rotatably arranged in the side wall of the box body at the pull-out opening, and can rotate within a range of 90 degrees; a fixed hasp is arranged on the side surface of the box body, which is far away from the rotating seat; a snap ring is arranged on the side surface of the upper cover far away from the first rotating shaft; the fixed hasp and the hasp ring correspond to each other and can be locked with each other;
when the box body is in work, the hasp on the box body is separated from the hasp ring on the upper cover, the upper cover is unlocked, then the upper cover is upwards opened and rotated for 180 degrees and then is horizontally placed, the upper cover is prevented from sliding off again after being opened, the use of an operator is prevented, meanwhile, after the operator opens the upper cover, the side covers at the pull-out openings at the two sides of the box body are opened, and the side covers are rotated for 90 degrees, so that the side covers are in a horizontal state, then the operator respectively grasps the two placing frames at the outermost sides of the two ends in the box body by two hands and pulls out the two placing frames through the pull-out openings at the two sides of the box body, because the placing frames are sequentially hinged end to end through the hinge blocks, after the operator pulls out the two placing frames at the two ends from the pull-out openings of the box body, the placing frames are finally arranged into a straight line along with the action of the operator, therefore, the placing rack is pulled out of the box body by an operator, and the placing racks are arranged in a straight line in the process, the position of the placing rack in the middle position relative to the box body is unchanged, the placing rack is prevented from being completely separated from the box body, the situation that the operator uses the placing rack in the using process is caused, the placing rack is deviated or the placing rack is toppled over, and the normal use of the operator is influenced, meanwhile, the placing racks are arranged in the box body, antigen monoclonal antibodies of multiple tumors or antigen monoclonal antibodies of different detection points of the same tumor can be stored in the same kit, the range or the detection accuracy of collecting a sample for detection is increased, the detection range and the detection effect of the kit are improved, meanwhile, in the using process, detection reagents in the box body can be stored in a classified mode according to different detection objects, different detection modes and different detection marks, and the same type or similar detection reagents are prevented from being stored in the storing holes in the same Put the storage hole on the frame to use marker pen to mark on the rack that corresponds, in the use, operating personnel pulls open the rack and arranges the straight line, and operating personnel of being convenient for seeks detection reagent storage position, accelerates operating personnel's operating speed, shortens the detection preparation time, improves detection speed.
Preferably, a rubber pad is arranged on the lower surface of the upper cover; when the upper cover is closed, the lower surface of the rubber mat can be tightly attached to the upper surface of the placing rack; the upper end of the test tube filled with the detection reagent in the storage hole exceeds the upper surface of the placing rack by 2-3 mm;
the during operation, place the test tube that has the detect reagent and enter into the hole of depositing on the rack, in the upper cover closed back, the in-process that removes or deposit the kit, the cushion contact and the extrusion on the upper cover lower surface are at the upper surface of rack, guarantee that the rack in the closed back box body of upper cover can not remove, avoid the detect reagent in the test tube to leak, and simultaneously, avoid the rack to bump in the box body, the test tube that leads to in the hole of depositing on the rack breaks, lead to the detect reagent loss, and simultaneously, after the upper cover is closed, because the upper end of test tube surpasss the upper surface of rack, therefore, the test tube receives the extrusion and fixed of cushion, prevent that the test tube from appearing rocking or deviating from the condition of depositing the hole, further guarantee the detect reagent's in test tube and the test tube safety, thereby improve the security of.
Preferably, the left side surface and the right side surface of the placing frame are respectively provided with a first rubber pad; an air cavity I is formed in the rubber pad I; a second rubber pad is arranged in the storage hole; an air cavity II is formed in the rubber pad II; the air cavity is positioned in the middle of the storage hole; the air cavity II is communicated with the air cavity I; the thickness of the side wall of the first air cavity is smaller than that of the side wall of the second air cavity;
when the rack is retracted into the box body, the rubber pads on the two sides of the rack are pressed by the rubber pads on the adjacent sides of the rack, so that the space of the air cavity I in the rubber pad I is reduced, the pressure is increased, meanwhile, the rubber pads on the two sides of the rack are contacted with each other in the process of retracting the rack, the acting force between the racks is buffered, the phenomenon that the rack is damaged due to collision between the rack and the box body after being retracted by an operator when the rack is retracted by the operator is prevented, meanwhile, the rubber pads can have certain elasticity after being pressed is avoided, when the kit is opened again for detection, the force for pulling the rack out by the operator is reduced, the labor intensity and the operation difficulty of the operator are reduced, meanwhile, the air cavity I is communicated with the air cavity II, and the pressure in the air cavity I is increased, gas in the air cavity I enters into the air cavity II, make the space increase in the air cavity II, rubber pad two is in the inflation of air cavity two departments, thereby the extrusion, the fixed reagent pipe that is arranged in depositing the hole, further avoid the pine of reagent pipe to take off or empty, and guarantee the fixed effect to the test tube, and simultaneously, after opening the side cap, operating personnel places the horizontal direction with the side cap, pull out the rack from the box body, the rack pulls out the back, the rubber pad of rack side is not receiving the extrusion, and simultaneously, the space of air cavity I in the rubber pad is the original state of recovering, the pressure reduction in the air cavity I, with the pressure reduction in the air cavity two of air cavity one intercommunication, rubber pad two is relieved its fixed to the test tube, be convenient for operating personnel to take and operate the test tube, when avoiding taking the test tube, the test tube is died in depositing the hole by the card, be difficult to take out, influence.
Preferably, a first movable cavity is formed in the side cover; a push rod is arranged in the first movable cavity; racks arranged in the vertical direction are mounted at the two ends of the push rod; a long through hole is formed in the side surface of the side cover, which is far away from the box body; the long through hole is positioned in the middle of the side cover; the long through hole is communicated to the first movable cavity; a toggle button is arranged in the strip through hole in a sliding manner; the toggle button is fixedly connected to the middle position of the push rod; a second movable cavity is formed in the side cover; the two movable cavities are respectively positioned at the left side and the right side of the first movable cavity; a locking gear is arranged in the second movable cavity; the locking gear is meshed with the rack on the push rod; the locking gear is fixedly connected with a locking rod; the locking rod can rotate along with the locking gear within a range of 90 degrees in the second movable cavity; a locking cavity is formed in the side wall of the pull-out opening in the box body; the locking cavity is opposite to the movable cavity II; after the locking rod rotates to the horizontal position, the tail end of the locking rod is inserted into a locking cavity in the box body;
when the side cover is required to be opened, an operator presses the toggle button to enable the toggle button to rise along the strip through hole, so that the push rod in the first movable cavity is driven to move upwards through the toggle button, meanwhile, as the locking gear is meshed with the rack on the push rod, when the push rod moves upwards, the push rod moves upwards in the first movable cavity, the locking gear is acted by the rack and rotates to drive the locking rod on the locking gear to rotate to enter the second movable cavity on the side cover, so that the locking rod leaves the locking cavity on the box body to unlock the side cover, meanwhile, when the box body is required to be closed, the side cover rotates from the horizontal position to the vertical position to enable the side cover to enter the pull-out opening, then the fluctuation button is pushed reversely to drive the push rod to move reversely, so that the locking gear is driven to rotate through the rack on the push rod, insert the locking lever in the box body the locking intracavity, accomplish the fixed to the side cap, and simultaneously, through the interact between locking lever and the locking chamber, thereby promote the relatively fixed effect between side cap and the box body, avoid depositing or removing the in-process at the kit, effort is not enough between side cap and the box body, lead to the locking inefficacy between side cap and the box body, make the rack in the box body stretch out from pull-out mouth department, reform transform in influencing the kit, and simultaneously, the locking lever through setting up can be effectively big improvement side cap and the joint strength between the box, prevent that the side cap from opening by oneself in the transportation or deposit the in-process side cap, lead to the rack in the box body to stretch out, influence detect and the transportation or the security of removing the in-process.
Preferably, a rubber layer is arranged on the side face of the locking rod, which is in contact with the locking cavity; an included angle is formed between the side surface of the locking rod, which is in contact with the inner wall of the locking cavity, and the wall of the locking cavity;
the during operation, after the side cap is closed, the locking lever enters into the locking intracavity of box body under the rotation of locking gear, and simultaneously, because the locking lever is installed the rubber layer with locking intracavity contact on the surface, there is the contained angle between the side of locking lever and the locking intracavity wall, can effectual increase the frictional force between locking lever and the locking intracavity wall, improve the stability of locking lever in the locking intracavity, avoid the locking lever to take place the displacement under external influence, lead to the locking lever not hard up to appear, lead to the locking inefficacy, the side cap is abnormal to be opened, influence the use and deposit of kit, remove.
Preferably, a flexible rod is mounted on the lower surface of the upper cover; the number of the flexible rods is two, and the two flexible rods are respectively positioned at two ends of the upper cover in the length direction; the flexible rod may flex but change in length; the flexible rod can be inserted into the box body; when the upper cover is closed, the flexible rod is completely inserted into the box body; when the flexible rod is completely inserted into the box body, the lower end of the flexible rod penetrates through the locking cavity and is inserted into the side wall of the box body below the locking cavity; a groove is formed in the part, located in the locking cavity, of the locking rod; the part of the flexible rod in the locking cavity passes through the groove on the locking rod; when the upper cover is opened, the flexible rod is pulled out of the part, and the lower end of the flexible rod leaves the locking cavity;
when the reagent box is in operation, after the upper cover is closed, the flexible rod on the upper cover is pushed by the upper cover to be completely inserted into the box body, the lower end of the flexible rod enters the locking cavity, meanwhile, the part of the lower end of the flexible rod, which is positioned in the locking cavity, penetrates through the groove on the locking rod, a certain friction force exists between the flexible rod and the locking rod to prevent the flexible rod from being drawn out, the opening force required after the upper cover is closed is increased, the locking force after the upper cover is closed is improved, the upper cover is prevented from being opened randomly to influence normal use, meanwhile, in the process of storing or moving the reagent box, if the fixed hasp on the reagent box is loosened from the hasp ring, when the upper cover cannot be locked, the friction force between the flexible rod and the locking rod can ensure that the upper cover cannot be opened under the action of slight external force, the safety of a test tube in the reagent box and a detection reagent in the test tube is, the upper cover is closed, and after the flexible rod inserted the recess completely, the locking lever received the extrusion of flexible rod, and the locking lever can not take place to remove in the locking intracavity to lock the locking lever through the flexible rod, guarantee before the upper cover is not opened, the side cap on the box body can not be opened, guarantee the security of the detection reagent in the box body.
The invention has the following beneficial effects:
1. according to the tumor marker detection kit, due to the arrangement of the placing frame and the hinging block, the placing frames in the kit body can be arranged in a straight line in the using process of operators, and the detection reagents placed in the kit body are arranged, so that the operators can conveniently distinguish and take the reagents in the using process.
2. According to the tumor marker detection kit, the flexible rod and the locking rod are arranged, so that the locking rod can be fixed in the locking cavity on the kit body through the flexible rod when the upper cover is closed, the locking rod is prevented from leaving the locking cavity when the upper cover is locked, the side cover is opened, the side cover can be opened only after the upper cover is opened, the stability of the kit for storing reagents is improved, and the leakage of the internal detection reagents caused by accidental opening of the kit is avoided.
3. According to the tumor marker detection kit, due to the arrangement of the first rubber pad, the first air cavity, the second rubber pad and the second air cavity, when the placing rack is retracted into the kit body, the two adjacent placing racks of the first rubber pad and the second rubber pad are used for buffering, so that the reagents stored on the placing racks are prevented from being influenced by direct contact and collision between the placing racks, and meanwhile, after the placing rack is retracted, the volume of the first air cavity is reduced, the pressure is increased, and the volume of the two air cavities is increased, so that test tubes containing the reagents on the two placing racks of the air cavities are further fixed, and the test tubes are placed to fall off or incline, and the.
Drawings
The invention will be further explained with reference to the drawings.
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a schematic view of the internal structure of the kit;
FIG. 3 is a partial cross-sectional view of a rack in a reagent cartridge;
FIG. 4 is an enlarged view of a portion of FIG. 1 at A;
in the figure: the box body 1, the rotating seat 11, the locking cavity 12, the fixed hasp 13, the hasp ring 14, the upper cover 2, the first rotating shaft 21, the rubber gasket 22, the flexible rod 23, the side cover 3, the second rotating shaft 31, the first movable cavity 32, the push rod 33, the toggle button 34, the strip through hole 341, the second movable cavity 35, the locking gear 36, the locking rod 361, the placing frame 4, the rotating connecting shaft 41, the hinge block 42, the connecting block 421, the storage hole 43, the first rubber gasket 44, the first air cavity 441, the second rubber gasket 45 and the second air cavity 451.
Detailed Description
In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further described with the specific embodiments.
As shown in fig. 1 to 4, the tumor marker detection kit of the present invention comprises a kit body 1, wherein an upper cover 2 is installed above the kit body 1; a first rotating shaft 21 is arranged on the upper cover 2; the upper end of the box body 1 is provided with a rotating seat 11; the rotating shaft is rotatably arranged in the rotating seat 11; the upper cover 2 rotates within a range of 180 degrees along the first rotating shaft 21; a placing rack 4 is arranged in the box body 1; the plurality of placing racks 4 are uniformly placed in the box body 1; the placing frame 4 is provided with a placing hole 43; a test tube for containing a detection reagent is placed in the storage hole 43; the appearance of the placing rack 4 is cuboid; the length direction of the placing frame 4 is perpendicular to the length direction of a first rotating shaft 21 on the upper cover 2; two ends of the upper surface of the placing rack 4 are provided with rotating connecting shafts 41; the placing racks 4 in the box body 1 are sequentially connected together from left to right end to end through the hinge blocks 42; the rotating connecting shafts 41 on the same side of two adjacent placing frames 4 are respectively hinged at two ends of the hinge block 42, and the rotating connecting shafts 41 can freely rotate; the hinged blocks 42 hinged to the rotating connecting shafts 41 at the two ends of the upper surface of the placing rack 4 are respectively positioned at the two sides of the placing rack 4; a connecting block 421 is arranged in the box body 1 and positioned at the center line of the box body 1 in the length direction; the connecting block 421 is positioned on the side surface far away from the rotating seat 11 in the box body 1, and the connecting block 421 is fixedly connected with the box body 1; the connecting block 421 is fixedly connected with a hinge block 42 positioned in the middle of the box body 1; the side surfaces of the left side and the right side of the box body 1 are provided with mutually symmetrical pull-out ports; a side cover 3 is arranged at the pull-out opening of the box body 1; a second rotating shaft 31 is arranged on the side cover 3; the second rotating shaft 31 is rotatably installed in the side wall of the box body 1 at the pull-out opening, and the second rotating shaft 31 can rotate within a range of 90 degrees; a fixed hasp 13 is arranged on the side surface of the box body 1 far away from the rotating seat 11; a snap ring 14 is arranged on the side surface of the upper cover 2 far away from the first rotating shaft 21; the fixed hasp 13 and the hasp ring 14 correspond to each other and can be locked with each other;
when the box body is in operation, the hasp on the box body 1 is separated from the hasp ring 14 on the upper cover 2, the upper cover 2 is unlocked, then the upper cover 2 is upwards opened and rotated for 180 degrees and then horizontally placed, the upper cover 2 is prevented from sliding off again after being opened, and the use of an operator is influenced, meanwhile, after the operator opens the upper cover 2, the side covers 3 at the pull-out openings at the two sides of the box body 1 are opened, the side covers 3 are rotated for 90 degrees, so that the side covers 3 are in a horizontal state, then the operator respectively grasps the two placing frames 4 at the outermost sides at the two ends in the box body 1 by using two hands, the two placing frames 4 are pulled out through the pull-out openings at the two sides of the box body 1, and because the placing frames 4 are sequentially hinged end to end through the hinge blocks 42, after the operator pulls out the two placing frames 4 at the two ends from the pull-out openings of the box body 1, the placing, meanwhile, because the box body 1 is provided with the connecting block 421 fixedly connected with the middle position hinge block 42, the placing frame 4 is pulled out of the box body 1 by an operator, and the placing frame 4 is arranged in a straight line, the position of the placing frame 4 in the middle position relative to the box body 1 is unchanged, so that the placing frame 4 is prevented from being completely separated from the box body 1, the placing frame 4 is deviated or the placing frame 4 is inclined in the using process of the operator, and the normal use of the operator is influenced, meanwhile, the placing frames 4 are arranged in the box body 1, so that the antigen monoclonal antibodies of various tumors or the antigen monoclonal antibodies of different detection points of the same tumor can be stored in the same kit, the detection range or the detection accuracy of collecting a sample is increased, the detection range and the detection effect of the kit are improved, and meanwhile, in the using process, the detection reagents in the box body 1 can be fixedly connected with the middle position hinge block 42 according, Different detection methods and different detection marker classify and deposit, prevent with class or similar detect reagent in the hole 43 of depositing on same rack 4 or the hole 43 of depositing on adjacent rack 4 in box body 1, and use marker pen to mark on the rack 4 that corresponds, in the use, operating personnel pulls open rack 4 and arranges the straight line, be convenient for operating personnel seeks detect reagent and deposits the position, accelerate operating personnel's operating speed, shorten the detection preparation time, improve detection speed.
As an embodiment of the present invention, a rubber pad 22 is mounted on the lower surface of the upper cover 2; when the upper cover 2 is closed, the lower surface of the rubber pad 22 can be tightly attached to the upper surface of the placing frame 4; the upper end of the test tube filled with the detection reagent in the storage hole 43 exceeds the upper surface of the placing rack 4 by 2-3 mm;
when in work, the test tube containing the detection reagent is placed into the storage hole 43 on the placing frame 4, after the upper cover 2 is closed, in the process of moving or storing the reagent box, the rubber pad 22 on the lower surface of the upper cover 2 contacts and extrudes on the upper surface of the placing frame 4, so that the placing frame 4 in the box body 1 can not move after the upper cover 2 is closed, the leakage of the detection reagent in the reagent box is avoided, meanwhile, the test tube in the storage hole 43 on the placing rack 4 is prevented from being broken to cause the loss of the detection reagent due to the collision of the placing rack 4 in the box body 1, and simultaneously, after the upper cover 2 is closed, the upper end of the test tube exceeds the upper surface of the placing frame 4, therefore, the test tube is extruded and fixed by the rubber cushion 22, the test tube is prevented from shaking or dropping out of the storage hole 43, further ensure the safety of the test tube and the detection reagent in the test tube, thereby improving the safety of the kit.
As an embodiment of the invention, the left side surface and the right side surface of the placing frame 4 are respectively provided with a first rubber pad 44; an air cavity I441 is formed in the rubber pad I44; a second rubber pad 45 is arranged in the storage hole 43; an air cavity II 451 is formed in the rubber pad II 45; the second air cavity 451 is positioned in the middle of the storage hole 43; the second air cavity 451 is communicated with the first air cavity 441; the thickness of the side wall of the air cavity I441 is smaller than that of the side wall of the air cavity II 451;
when the rack 4 is retracted into the box body 1, the rubber pads 44 on two sides of the rack 4 are squeezed by the rubber pads 44 on the side surfaces of the adjacent rack 4, so that the space of the air cavities 441 in the rubber pads 44 is reduced, the pressure is increased, meanwhile, in the process of retracting the rack 4, the rubber pads 44 on two sides of the rack 4 are contacted with each other to buffer the acting force between the racks 4, the situation that the rack 4 is damaged due to collision between the racks 4 retracted into the box body 1 caused by too fast retracting speed of an operator when the rack 4 is retracted is prevented, meanwhile, the rubber pads 44 can have certain elasticity after being squeezed, when the reagent box is opened again for detection, the force for pulling the operator out of the rack 4 is reduced, the labor intensity and the operation difficulty of the operator are reduced, and meanwhile, because the air cavities 441 are communicated with the air cavities 451, after the pressure in the air cavity I441 rises, the air in the air cavity I441 enters the air cavity II 451, so that the space in the air cavity II 451 is increased, the rubber gasket II 45 expands at the position of the air cavity II 451, so as to extrude and fix the reagent tube positioned in the storage hole 43, further avoid the loosening or toppling of the reagent tube, and ensure the fixing effect on the test tube, meanwhile, after the side cover 3 is opened, an operator places the side cover 3 in the horizontal direction, pulls out the placing rack 4 from the box body 1, after the placing rack 4 is pulled out, the rubber gasket I44 on the side surface of the placing rack 4 is not extruded, meanwhile, the space of the air cavity I441 in the rubber gasket I44 is restored to the original state, the pressure in the air cavity I441 is reduced, the pressure in the air cavity II 451 communicated with the air cavity I441 is reduced, the rubber gasket II 45 relieves the fixation of the test tube, the operator and the test tube operation are convenient, and, the test tube is stuck to the storage hole 43 and is difficult to take out, which affects the use of the reagent cartridge.
As an embodiment of the present invention, a first movable cavity 32 is formed in the side cover 3; a push rod 33 is arranged in the first movable cavity 32; racks arranged in the vertical direction are mounted at two ends of the push rod 33; a long through hole 341 is formed in the side surface of the side cover 3 away from the box body 1; the long through hole 341 is located at the middle position of the side cover 3; the long through hole 341 is communicated to the first movable cavity 32; a toggle button 34 is arranged in the strip through hole 341 in a sliding manner; the toggle button 34 is fixedly connected to the middle position of the push rod 33; a second movable cavity 35 is formed in the side cover 3; the two movable cavities 35 are respectively positioned at the left side and the right side of the first movable cavity 32; a locking gear 36 is arranged in the second movable cavity 35; the locking gear 36 is meshed with the rack on the push rod 33; the locking gear is fixedly connected with a locking rod 361; the locking rod 361 can rotate along with the locking gear 36 in the second movable cavity 35 within a range of 90 degrees; a locking cavity 12 is formed in the side wall of the pull-out opening of the box body 1; the locking cavity 12 is opposite to the second movable cavity 35; after the locking rod 361 rotates to the horizontal position, the tail end of the locking rod 361 is inserted into the locking cavity 12 in the box body 1;
in operation, when the side cover 3 needs to be opened, an operator presses the toggle button 34 to lift the toggle button 34 along the long through hole 341, so as to drive the push rod 33 in the first movable cavity 32 to move upwards through the toggle button 34, and meanwhile, as the locking gear 36 is meshed with the rack on the push rod 33, when the push rod 33 moves upwards, the push rod 33 moves upwards in the first movable cavity 32, the locking gear 36 is acted by the rack to rotate, so as to drive the locking rod 361 on the locking gear 36 to rotate and enter the second movable cavity 35 on the side cover 3, so as to make the locking rod 361 leave the locking cavity 12 on the box body 1, and release the locking of the box body 1 to the side cover, and meanwhile, when the box body 1 needs to be closed, the side cover 3 is rotated from the horizontal position to the vertical position to make the side cover 3 enter the pull-out opening, and then the fluctuation button is pushed reversely, the pushing rod 33 is driven to move reversely, so that the locking gear 36 is driven to rotate reversely by the rack on the pushing rod 33, the locking rod 361 is inserted into the locking cavity 12 in the box body 1, the fixation of the side cover 3 is completed, and at the same time, through the interaction between the locking rod 361 and the locking cavity 12, thereby improving the relative fixing effect between the side cover 3 and the box body 1, avoiding the problems that in the process of storing or moving the reagent box, the acting force between the side cover 3 and the box body 1 is insufficient, so that the locking between the side cover 3 and the box body 1 is invalid, the placing frame 4 in the box body 1 extends out from the pull-out opening, the transformation in the kit is influenced, simultaneously, the locking lever 361 that sets up can be effectively big improvement side cap 3 and the joint strength between the box, prevents that side cap 3 from opening by oneself in the transportation or deposit the in-process side cap 3, leads to rack 4 in the box body 1 to stretch out, influences the security that detects and to the transportation of kit or removal in-process kit.
As an embodiment of the present invention, a rubber layer may be installed on a side surface of the locking rod 361 contacting the locking chamber 12; an included angle is formed between the side surface of the locking rod 361, which is in contact with the inner wall of the locking cavity 12, and the wall of the locking cavity 12;
during operation, after side cover 3 is closed, locking lever 361 enters into the locking chamber 12 of box body 1 under locking gear 36 rotates, simultaneously, because install the rubber layer on the surface that locking lever 361 and locking chamber 12 contact, there is the contained angle between the side of locking lever 361 and the locking chamber 12 inner wall, can effectual increase the frictional force between locking lever 361 and the locking chamber 12 inner wall, improve the stability of locking lever 361 in locking chamber 12, avoid locking lever 361 to take place the displacement under the influence of the external world, lead to locking lever 361 to appear becoming flexible, lead to the locking inefficacy, side cover 3 is improper to be opened, influence the use and deposit, the removal of kit.
As an embodiment of the present invention, a flexible rod 23 is mounted on the lower surface of the upper cover 2; the number of the flexible rods 23 is two, and the two flexible rods are respectively positioned at two ends of the upper cover 2 in the length direction; the flexible rod 23 can flex but vary in length; the flexible rod 23 can be inserted into the box body 1; when the upper cover 2 is closed, the flexible rod 23 is completely inserted into the box body 1; when the flexible rod 23 is completely inserted into the box body 1, the lower end of the flexible rod 23 passes through the locking cavity 12 and is inserted into the side wall of the box body 1 below the locking cavity 12; a groove is formed in the part, located in the locking cavity 12, of the locking rod 361; the portion of the flexible rod 23 located in the locking chamber 12 passes through the groove on the locking bar 361; when the upper cover 2 is opened, the flexible rod 23 is pulled out, and the lower end of the flexible rod 23 leaves the locking cavity 12;
when the reagent box is in operation, after the upper cover 2 is closed, the flexible rod 23 on the upper cover 2 is pushed by the upper cover 2 to be completely inserted into the box body 1, the lower end of the flexible rod 23 enters the locking cavity 12, meanwhile, the part of the lower end of the flexible rod 23, which is positioned in the locking cavity 12, penetrates through the groove on the locking rod 361, a certain friction force exists between the flexible rod 23 and the locking rod 361, the flexible rod 23 is prevented from being drawn out, the opening force required after the upper cover 2 is closed is increased, the locking force after the upper cover 2 is closed is improved, the upper cover 2 is prevented from being opened randomly to influence normal use, meanwhile, in the process of storing or moving the reagent box, if the fixed hasp 13 on the reagent box is loosened from the hasp ring 14, when the upper cover 2 cannot be locked, the upper cover 2 can be prevented from being opened under the action of slight external force through the friction force between the flexible rod 23 and the locking rod 361, and the safety of test tubes in, meanwhile, as the flexible rod 23 is embedded with the groove on the locking rod 361, the upper cover 2 is closed, and after the flexible rod 23 is completely inserted into the groove, the locking rod 361 is extruded by the flexible rod 23, the locking rod 361 cannot move in the locking cavity 12, so that the locking rod 361 is locked by the flexible rod 23, and before the upper cover 2 is not opened, the side cover 3 on the box body 1 cannot be opened, and the safety of the detection reagent in the box body 1 is ensured.
The specific working process is as follows:
when the box body 2 is in work, the hasp on the box body 1 is separated from the hasp ring 14 on the upper cover 2, the upper cover 2 is unlocked, then the upper cover 2 is upwards opened and horizontally placed after being rotated for 180 degrees, meanwhile, after the upper cover 2 is opened by an operator, the side covers 3 at the pull-out openings at the two sides of the box body 1 are opened, and the side covers 3 are rotated for 90 degrees, so that the side covers 3 are in a horizontal state, then the operator respectively grasps the two placing frames 4 at the outermost sides of the two ends in the box body 1 by two hands, and pulls out the two placing frames 4 through the pull-out openings at the two sides of the box body 1, because the placing frames 4 are sequentially hinged end to end through the hinge blocks 42, after the operator pulls out the two placing frames 4 at the two ends from the pull-out openings of the box body 1, the placing frames 4 are finally arranged into a straight line along with the action of the operator, and simultaneously, because the, therefore, in the process that an operator pulls the placing rack 4 out of the box body 1 and arranges the placing racks 4 in a straight line, the position of the placing rack 4 in the middle position relative to the box body 1 is unchanged, and the placing rack 4 is prevented from being completely separated from the box body 1; after the upper cover 2 is closed, in the process of moving or storing the kit, the rubber pad 22 on the lower surface of the upper cover 2 is contacted with and extruded on the upper surface of the placing frame 4, and meanwhile, after the upper cover 2 is closed, the upper end of the test tube exceeds the upper surface of the placing frame 4, so that the test tube is extruded and fixed by the rubber pad 22; after the placing rack 4 is retracted into the box body 1, the rubber pads 44 on the two sides of the placing rack 4 are squeezed by the rubber pads 44 on the adjacent sides of the placing rack 4, so that the space of the air cavity 441 in the rubber pads 44 is reduced, the pressure is increased, meanwhile, in the process of retracting the placing rack 4, the rubber pads 44 on the two sides of the placing rack 4 are contacted with each other, the acting force between the placing rack 4 is buffered, meanwhile, as the air cavity 441 is communicated with the air cavity two 451, after the pressure in the air cavity 441 is increased, the air in the air cavity 441 enters the air cavity two 451, the space in the air cavity two 451 is increased, the rubber pads 45 are expanded at the air cavity two 451, so as to squeeze and fix the reagent tube positioned in the storage hole 43, meanwhile, after the side cover 3 is opened, an operator places the side cover 3 in the horizontal direction, pulls the placing rack 4 out of the box body 1, pulls out the placing rack 4, the rubber pad I44 on the side surface of the placing rack 4 is not extruded, meanwhile, the space of the air cavity I441 in the rubber pad I44 is restored to the original state, the pressure in the air cavity I441 is reduced, the pressure in the air cavity II 451 communicated with the air cavity I441 is reduced, and the rubber pad II 45 releases the fixation of the test tube; when the side cover 3 needs to be opened, an operator presses the toggle button 34 to lift the toggle button 34 along the long through hole 341, so that the push rod 33 in the first movable cavity 32 is driven to move upwards by the toggle button 34, meanwhile, because the locking gear 36 is meshed with the rack on the push rod 33, when the push rod 33 moves upwards, the push rod 33 moves upwards in the first movable cavity 32, the locking gear 36 is acted by the rack to rotate, the locking rod 361 on the locking gear 36 is driven to rotate to enter the second movable cavity 35 on the side cover 3, so that the locking rod 361 leaves the locking cavity 12 on the box body 1 to release the locking of the box body 1 to the side cover, meanwhile, when the box body 1 needs to be closed, the side cover 3 is rotated from the horizontal position to the vertical position to enable the side cover 3 to enter the pull-out opening, then, the fluctuation button is pushed reversely to drive the push rod 33 to move reversely, thereby, the gear belt on the pushing rod 33 drives the locking gear 36 to rotate reversely, the locking rod 361 is inserted into the locking cavity 12 in the box body 1, and the fixation of the side cover is completed; when the upper cover 2 is closed, the flexible rod 23 on the upper cover 2 is pushed by the upper cover 2 to be fully inserted into the box body 1, the lower end of the flexible rod 23 enters the locking cavity 12, meanwhile, the part of the lower end of the flexible rod 23, which is positioned in the locking cavity 12, passes through the groove on the locking rod 361, the locking rod 361 is pressed by the flexible rod 23, and the locking rod 361 cannot move in the locking cavity 12.
The foregoing illustrates and describes the principles, general features, and advantages of the present invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (5)
1. A tumor marker detection kit comprises a kit body (1), and is characterized in that: an upper cover (2) is arranged above the box body (1); a first rotating shaft (21) is mounted on the upper cover (2); the upper end of the box body (1) is provided with a rotating seat (11); the rotating shaft is rotatably arranged in the rotating seat (11); the upper cover (2) rotates within a 180-degree range along the first rotating shaft (21); a placing rack (4) is arranged in the box body (1); the plurality of placing racks (4) are uniformly placed in the box body (1); a storage hole (43) is formed in the placing frame (4); a test tube for containing a detection reagent is placed in the storage hole (43); the appearance of the placing rack (4) is cuboid; the length direction of the placing frame (4) is vertical to the length direction of a first rotating shaft (21) on the upper cover (2); two ends of the upper surface of the placing rack (4) are provided with rotating connecting shafts (41); the placing racks (4) in the box body (1) are sequentially connected together from left to right end to end through hinge blocks (42); the rotating connecting shafts (41) on the same side of two adjacent placing frames (4) are respectively hinged to two ends of the hinge block (42), and the rotating connecting shafts (41) can rotate freely; hinged blocks (42) hinged by the rotary connecting shafts (41) at the two ends of the upper surface of the placing rack (4) are respectively positioned at the two sides of the placing rack (4); a connecting block (421) is arranged in the box body (1) and is positioned on the center line of the box body (1) in the length direction; the connecting block (421) is positioned on the side surface, far away from the rotating seat (11), in the box body (1), and the connecting block (421) is fixedly connected with the box body (1); the connecting block (421) is fixedly connected with a hinge block (42) positioned in the middle of the box body (1); the side surfaces of the left side and the right side of the box body (1) are provided with symmetrical pull-out ports; a side cover (3) is arranged at the pull-out opening of the box body (1); a second rotating shaft (31) is mounted on the side cover (3); the second rotating shaft (31) is rotatably arranged in the side wall of the box body (1) at the pull-out opening, and the second rotating shaft (31) can rotate within a range of 90 degrees; a fixed hasp (13) is arranged on the side surface of the box body (1) far away from the rotating seat (11); a snap ring (14) is arranged on the side surface, away from the first rotating shaft (21), of the upper cover (2); the fixed hasp (13) and the hasp ring (14) correspond to each other and can be locked with each other;
the left side surface and the right side surface of the placing frame (4) are respectively provided with a first rubber pad (44); an air cavity I (441) is formed in the rubber gasket I (44); a second rubber pad (45) is arranged in the storage hole (43); a second air cavity (451) is formed in the second rubber pad (45); the second air cavity (451) is positioned in the middle of the storage hole (43); the air cavity II (451) is communicated with the air cavity I (441); the thickness of the side wall of the air cavity I (441) is smaller than that of the side wall of the air cavity II (451).
2. The tumor marker detection kit according to claim 1, wherein: a rubber pad (22) is arranged on the lower surface of the upper cover (2); when the upper cover (2) is closed, the lower surface of the rubber pad (22) can be tightly attached to the upper surface of the placing rack (4); the upper end of the test tube filled with the detection reagent in the storage hole (43) exceeds the upper surface of the placing rack (4) by 2-3 mm.
3. The tumor marker detection kit according to claim 1, wherein: a first movable cavity (32) is formed in the side cover (3); a push rod (33) is arranged in the first movable cavity (32); racks arranged in the vertical direction are mounted at two ends of the push rod (33); a long-strip through hole (341) is formed in the side surface of the side cover (3) far away from the box body (1); the strip through hole (341) is positioned in the middle of the side cover (3); the strip through hole (341) is communicated with the first movable cavity (32); a toggle button (34) is arranged in the strip through hole (341) in a sliding way; the toggle button (34) is fixedly connected to the middle position of the push rod (33); a second movable cavity (35) is formed in the side cover (3); the two movable cavities (35) are respectively positioned at the left side and the right side of the first movable cavity (32); a locking gear (36) is arranged in the second movable cavity (35); the locking gear (36) is meshed with the rack on the push rod (33); the locking gear is fixedly connected with a locking rod (361); the locking rod (361) can rotate along with the locking gear (36) within a range of 90 degrees in the second movable cavity (35); a locking cavity (12) is formed in the side wall of the pull-out opening in the box body (1); the locking cavity (12) is opposite to the second movable cavity (35); after the locking rod (361) rotates to the horizontal position, the tail end of the locking rod (361) is inserted into a locking cavity (12) in the box body (1).
4. The tumor marker detection kit according to claim 3, wherein: a rubber layer is arranged on the side face, which can be contacted with the locking cavity (12), of the locking rod (361); an included angle is formed between the side face, which is in contact with the inner wall of the locking cavity (12), of the locking rod (361) and the wall of the locking cavity (12).
5. The tumor marker detection kit according to claim 4, wherein: a flexible rod (23) is arranged on the lower surface of the upper cover (2); the number of the flexible rods (23) is two, and the two flexible rods are respectively positioned at two ends of the upper cover (2) in the length direction; the flexible rod (23) can be bent but the length is changed; the flexible rod (23) can be inserted into the box body (1); when the upper cover (2) is closed, the flexible rod (23) is completely inserted into the box body (1); when the flexible rod (23) is completely inserted into the box body (1), the lower end of the flexible rod (23) penetrates through the locking cavity (12) and is inserted into the side wall of the box body (1) below the locking cavity (12); a groove is formed in the part, located in the locking cavity (12), of the locking rod (361); the part of the flexible rod (23) positioned in the locking cavity (12) passes through a groove on the locking rod (361); when the upper cover (2) is opened, the flexible rod (23) is pulled out of the part, and the lower end of the flexible rod (23) leaves the locking cavity (12).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010838945.6A CN111896739B (en) | 2020-08-19 | 2020-08-19 | Tumor marker detection kit |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010838945.6A CN111896739B (en) | 2020-08-19 | 2020-08-19 | Tumor marker detection kit |
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| CN111896739A CN111896739A (en) | 2020-11-06 |
| CN111896739B true CN111896739B (en) | 2021-06-01 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112630453A (en) * | 2020-12-23 | 2021-04-09 | 贵州金域医学检验中心有限公司 | Constant temperature kit for gynecological tumor marker detection and detection method thereof |
| CN112903666B (en) * | 2021-01-18 | 2021-09-28 | 北京中科健兰生物科技有限公司 | Application method of urine exfoliated cell detection kit |
| CN114671121B (en) * | 2022-05-30 | 2022-08-16 | 山东第一医科大学附属省立医院(山东省立医院) | Tumor marker detection kit |
| CN115029231B (en) * | 2022-08-12 | 2022-10-28 | 河北巴纳克医疗器械有限公司 | Inspection device for oncology department |
| CN115771667B (en) * | 2023-02-10 | 2023-06-27 | 武汉明德璟泓医疗科技有限公司 | Tumor biomarker detection kit and application method thereof |
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