CN115285506A

CN115285506A - Kit for drug sensitivity test of acute myelogenous leukemia

Info

Publication number: CN115285506A
Application number: CN202210969347.1A
Authority: CN
Inventors: 韩利杰; 桑丽娜; 汤平; 刘超
Original assignee: First Affiliated Hospital of Zhengzhou University
Current assignee: First Affiliated Hospital of Zhengzhou University
Priority date: 2022-08-12
Filing date: 2022-08-12
Publication date: 2022-11-04

Abstract

The invention relates to the technical field of medicine detection equipment, in particular to a kit for acute myelogenous leukemia drug sensitivity test, which comprises a box body, wherein a box plate is rotatably arranged at the top of the box body, a fixed plate is fixedly arranged in the box body, a plurality of uniformly arranged test tube holes are formed in the top of the fixed plate, four fixing columns which are arranged in a rectangular shape are arranged at the bottom of the fixed plate, a bottom plate is arranged at the bottom ends of the four fixing columns, a pushing mechanism is arranged on the side part of the box plate, and a clamping mechanism positioned between the fixed plate and the bottom plate is arranged on the pushing mechanism. According to the invention, when the box body needs to be moved, the handle is pulled to move out of the clamping groove, the handle moves to drive the L-shaped clamping rod to move so as to deform the fixing spring, at the moment, the box plate can rotate, and the box plate rotates to enable the arc-shaped grooves in the vertical plates to be fixed with the side parts of the test tubes respectively, so that the box body is convenient to transfer in various departments.

Description

Kit for drug sensitivity test of acute myelogenous leukemia

Technical Field

The invention relates to the technical field of medicine detection equipment, in particular to a kit for acute myelogenous leukemia drug sensitivity test.

Background

When acute myeloid leukemia is tested for drug susceptibility, different chemotherapeutics need to be tested for drug susceptibility, so as to screen suitable chemotherapeutics, the existing test is carried out separately in different test tubes, and after the test, a plurality of analyses need to be carried out, and the chemotherapy drugs are transferred in each department.

When placing a plurality of test tubes that are used for the later stage test screening, current kit needs to be fixed the test tube alone one by one, and is fixed loaded down with trivial details, the quick test of being not convenient for, and not convenient to use, we propose a kit that is used for acute myeloid leukemia drug sensitivity to test.

Disclosure of Invention

The invention aims to provide a kit for acute myelogenous leukemia drug sensitivity test, which solves the problems in the background technology.

In order to achieve the purpose, the invention provides the following technical scheme: the utility model provides a kit for quick test of acute myeloid leukemia medicine, includes the box body, the top of box body is rotated and is installed the box board, fixed mounting has the fixed plate in the box body, a plurality of test tube holes that evenly set up are seted up at the top of fixed plate, four fixed columns that are the rectangle setting are installed to the bottom of fixed plate, four the bottom plate is installed to the bottom of fixed column, pushing mechanism is installed to the lateral part of box board, the last installation of pushing mechanism is located the fixed plate with clamping mechanism between the bottom plate, adsorption apparatus is installed to the bottom of box body, adsorption apparatus with the cooperation installation of pushing mechanism.

Preferably, pushing mechanism including rotate install in two of box board bottom link up the pole, two the bottom of linking the pole all rotates and installs the locating lever, two all slide on the locating lever and cup jointed the locating frame, two the lateral part of locating frame all install in on one side inner wall of box body, two the connecting rod is installed to the bottom of locating lever, the installation pole is installed to the lateral part of connecting rod, the installation pole with adsorption device connects, the top of installation pole is installed and is compressed tightly the unit, compress tightly the unit with clamping mechanism connects.

Preferably, the compressing unit comprises a sliding rod installed on the inner wall of one side of the box body, a cross rod is sleeved on the sliding rod in a sliding mode, two limit blocks are installed at the bottom of the cross rod, two limit rods are installed on the side portions, close to each other, of the limit blocks, a compressing block is sleeved on the limit rods in a sliding mode, a pulling rod is installed at the bottom of the compressing block in a rotating mode, the bottom end of the pulling rod is installed on the top of the installing rod in a rotating mode, limiting springs are sleeved on the limit rods, the two ends of the limiting springs are installed on the side portions, close to each other, of the limit blocks respectively, and the cross rod is connected with the clamping mechanism.

Preferably, the clamping mechanism comprises a plurality of vertical plates arranged on the side portions of the cross rod, arc-shaped grooves are formed in the side portions of the vertical plates, and the arc-shaped grooves correspond to the positions of the test tube holes respectively.

Preferably, the adsorption mechanism including install in the removal frame of installation pole one end, four piston rods, four are installed to the bottom of removing the frame the piston is all installed to the piston rod bottom, four absorption holes have been seted up on the bottom side inner wall of box body, four equal fixed mounting has a piston cover in the absorption hole, four the piston is respectively sliding installation in four in the piston cover, four the sucking disc that is linked together is all installed to the bottom of piston cover, the lateral part of removing the frame is installed and is limited bit cell, four stabilizer blades, four are installed to the bottom of box body the stabilizer blade with four the position of sucking disc is corresponding.

Preferably, the limiting unit comprises a limiting hole formed in the inner wall of one side of the box body, a straight rod is slidably mounted in the limiting hole, a clamping groove is formed in the side portion of the moving frame, the straight rod is close to one end of the piston rod and extends into the clamping groove, an L-shaped clamping rod is mounted at the bottom of the straight rod and corresponds to the clamping groove in position, and the side portion of the L-shaped clamping rod is connected with the inner wall of the box body through a fixing spring.

Preferably, one end of the straight rod, which is far away from the piston, extends out of the box body and is provided with a handle.

Preferably, a handle is arranged at the top of the box plate.

In conclusion, the beneficial effects of the invention are as follows:

when the test tube box is used, test tubes can be placed in the test tube holes, the plurality of test tubes can be placed through the arrangement of the plurality of test tube holes, the bottoms of the test tubes are in contact with the top of the bottom plate after the test tubes are placed, and the box body can be adsorbed on the placing plane through the arrangement of the four suckers, so that the test tube box can be stably placed.

According to the invention, when the box body needs to be moved, the handle is pulled to move out of the clamping groove, the handle moves to drive the L-shaped clamping rod to move so as to deform the fixing spring, at the moment, the box plate can rotate, and the box plate rotates to enable the arc-shaped grooves in the vertical plates to be fixed with the side parts of the test tubes respectively, so that the box body is convenient to transfer in various departments.

According to the invention, when the box body needs to be moved, the box plate rotates to drive the two connecting rods to rotate, the two connecting rods rotate to drive the two positioning rods to move downwards, the two positioning rods move to drive the connecting rods, the mounting rods and the moving frame to move downwards, and the moving frame moves downwards to drive the four piston rods and the four pistons to move, so that air in the piston sleeves is discharged, the four suckers are prevented from adsorbing any more, and the box body can be moved at the later stage conveniently.

Drawings

In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative efforts.

FIG. 1 is a perspective view of a first embodiment of the present invention;

FIG. 2 is a perspective view of a second embodiment of the present invention;

FIG. 3 is a schematic view of a first perspective internal view of the present invention;

FIG. 4 is a schematic view of a second perspective internal view of the present invention;

FIG. 5 is an enlarged schematic view of the structure at A in FIG. 4;

FIG. 6 is a side cut-away view of the present invention;

fig. 7 is a partial structure diagram of fig. 5.

In the figure: 1. a box body; 2. a box plate; 3. a fixing plate; 4. a test tube hole; 5. fixing a column; 6. a base plate; 7. a cross bar; 8. a vertical plate; 9. an arc-shaped slot; 10. a slide bar; 11. a limiting block; 12. a limiting rod; 13. a limiting spring; 14. a compression block; 15. pulling a rod; 16. positioning a rod; 17. a positioning frame; 18. a connecting rod; 19. mounting a rod; 20. moving the frame; 21. a piston rod; 22. a piston; 23. a piston sleeve; 24. a suction cup; 25. a leg; 26. a connecting rod; 27. a card slot; 28. a straight rod; 29. a handle; 30. a fixed spring; 31. l-shaped clamping rods.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without making any creative effort based on the embodiments in the present invention, belong to the protection scope of the present invention.

Example one

Referring to fig. 1-7, a kit for acute myelogenous leukemia drug sensitivity test, comprises a box body 1, a box plate 2 is rotatably installed at the top of the box body 1, a fixed plate 3 is fixedly installed in the box body 1, a plurality of test tube holes 4 which are uniformly arranged are formed in the top of the fixed plate 3, four fixed columns 5 which are arranged in a rectangular mode are installed at the bottom of the fixed plate 3, a bottom plate 6 is installed at the bottom ends of the four fixed columns 5, a pushing mechanism is installed on the lateral portion of the box plate 2, a clamping mechanism which is located between the fixed plate 3 and the bottom plate 6 is installed on the pushing mechanism, an adsorption mechanism is installed at the bottom of the box body 1, and the adsorption mechanism is installed in cooperation with the pushing mechanism.

Example two

Based on the embodiment 1, the pushing mechanism comprises two linking rods 26 rotatably mounted at the bottom of the box plate 2, positioning rods 16 are rotatably mounted at the bottom ends of the two linking rods 26, positioning frames 17 are slidably sleeved on the two positioning rods 16, the side portions of the two positioning frames 17 are mounted on the inner wall of one side of the box body 1, connecting rods 18 are mounted at the bottom ends of the two positioning rods 16, mounting rods 19 are mounted at the side portions of the connecting rods 18, the mounting rods 19 are connected with the adsorption mechanism, and a pressing unit is mounted at the top of the mounting rods 19 and connected with the clamping mechanism. The box plate 2 can rotate, the box plate 2 rotates to drive the two connecting rods 26 to rotate, and the two connecting rods 26 rotate to drive the two positioning rods 16 to move downwards, so that all test tubes are fixed conveniently.

EXAMPLE III

Based on above-mentioned

embodiment

1 or 2, compress tightly the unit including installing slide bar 10 on 1 one side inner wall of box body, slide bar 10 is gone up to slide and is cup jointed horizontal pole 7, two stopper 11 are installed to the bottom of horizontal pole 7, gag lever post 12 is installed to the lateral part that two stopper 11 are close to each other, slide and have been cup jointed compact heap 14 on gag lever post 12, the bottom of compact heap 14 is rotated and is installed pulling rod 15, the bottom of pulling rod 15 is rotated and is installed on the top of installation pole 19, spacing spring 13 has been cup jointed on gag lever post 12, spacing spring 13's both ends are installed respectively in compact heap 14, stopper 11 is close to each other on the lateral part, horizontal pole 7 is connected with clamping mechanism. Through the setting of spacing spring 13, be convenient for extrude fixedly.

Example four

Based on above-mentioned

embodiment

1, 2 or 3, clamping mechanism is including installing in a plurality of risers 8 of horizontal pole 7 lateral part, and arc 9 has all been seted up to the lateral part of a plurality of risers 8, and a plurality of arc 9 correspond with the position of a plurality of test tube holes 4 respectively. Horizontal pole 7 slides on slide bar 10 to make arc 9 on a plurality of risers 8 respectively with the lateral part contact of a plurality of test tubes, a plurality of arc 9 can't continue to remove this moment, installation pole 19 continues to remove and makes compact heap 14 slide on gag lever post 12, thereby makes spacing spring 13 take place to deform, compresses tightly a plurality of test tubes under spacing spring 13's reaction force, thereby fixes.

EXAMPLE five

Based on above-mentioned

embodiment

1, 2, 3 or 4, adsorption apparatus constructs including installing in the removal frame 20 of 19 one ends of installation pole, four piston rods 21 are installed to the bottom of removing frame 20, piston 22 is all installed to four piston rod 21 bottoms, four absorption holes have been seted up on the bottom side inner wall of box body 1, equal fixed mounting has piston sleeve 23 in four absorption holes, four piston 22 respectively slidable mounting are in four piston sleeve 23, the sucking disc 24 that is linked together is all installed to the bottom of four piston sleeves 23, the lateral part installation limit bit unit of removing frame 20, four stabilizer blades 25 are installed to the bottom of box body 1, four stabilizer blades 25 are corresponding with the position of four sucking discs 24. Through the setting of four sucking discs 24, can be so that box body 1 adsorbs on placing the plane, thereby stably place, 2 rotations of box board drive two links up pole 26 and rotate, two links up pole 26 rotate and drive two locating levers 16 downstream, two locating levers 16 remove and drive connecting rod 18, installation pole 19 and removal frame 20 downstream, removal frame 20 downstream drives four piston rods 21 and four piston 22 and removes, thereby make the air escape in the piston bush 23, thereby make four sucking discs 24 no longer adsorb, be convenient for 1 later stage of box body to remove.

EXAMPLE six

Based on the

above embodiments

1, 2, 3, 4, or 5, the limiting unit includes a limiting hole formed in the inner wall of one side of the box body 1, a straight rod 28 is slidably installed in the limiting hole, a clamping groove 27 is formed in the lateral portion of the movable frame 20, one end of the straight rod 28, which is close to the piston rod 21, extends into the clamping groove 27, an L-shaped clamping rod 31 is installed at the bottom of the straight rod 28, the L-shaped clamping rod 31 corresponds to the clamping groove 27, and the lateral portion of the L-shaped clamping rod 31 is connected to the inner wall of the box body 1 through a fixing spring 30. By the arrangement of the limit unit, the position of the box plate 2 can be fixed when the box plate 2 is closed or opened.

EXAMPLE seven

Based on the

above embodiments

1, 2, 3, 4, 5 or 6, one end of the straight rod 28 far away from the piston 22 extends out of the box body 1 and is provided with a handle 29. The straight rod 28 is convenient for a user to move through the arrangement of the handle 29.

Example eight

Based on the

above embodiments

1, 2, 3, 4, 5, 6 or 7, the top of the box panel 2 is provided with a handle. Through the setting of handle, be convenient for remove.

The working principle of the invention is as follows: when the test tube box is used, test tubes can be placed in the test tube holes 4, the test tubes can be placed through the arrangement of the test tube holes 4, after the test tubes are placed, the bottoms of the test tubes are in contact with the top of the bottom plate 6, the box body 1 can be adsorbed on a placing plane through the arrangement of the four suckers 24, and therefore the test tubes can be stably placed, when the box body 1 needs to be moved, the handle 29 is pulled to be moved out of the clamping groove 27, the handle 29 moves to drive the L-shaped clamping rod 31 to move, so that the fixing spring 30 deforms, at the moment, the box plate 2 can rotate, the box plate 2 rotates to drive the two connecting rods 26 to rotate, the two connecting rods 26 rotate to drive the two positioning rods 16 to move downwards, the two positioning rods 16 move downwards to drive the connecting rods 18, the mounting rods 19 and the moving frame 20 to move downwards, the moving frame 20 moves downwards to drive the four piston rods 21 and the four pistons 22 to move, so that air in the piston sleeve 23 is discharged, so that the four suckers 24 are not adsorbed any more, and the box body 1 can move in the later stage;

meanwhile, the connecting rod 18 moves to pull the pulling rod 15 to move, the pulling rod 15 slides on the limiting rod 12, so that the limiting spring 13 deforms, the cross rod 7 slides on the sliding rod 10 under the action of the limiting spring 13, so that the arc-shaped grooves 9 in the vertical plates 8 are respectively contacted with the side portions of the test tubes, at the moment, the arc-shaped grooves 9 cannot move continuously, the mounting rod 19 moves continuously to enable the pressing block 14 to slide on the limiting rod 12, so that the limiting spring 13 deforms, and the test tubes are pressed under the reaction force of the limiting spring 13 to be fixed;

when the box plate 2 is closed, the clamping groove 27 corresponds to the L-shaped clamping rod 31 at the moment, the handle 29 is loosened, the L-shaped clamping rod 31 enters the clamping groove 27 under the acting force of the fixing spring 30, and therefore the box plate is fixed and is convenient to move through the arrangement of the handle.

Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still make modifications to the technical solutions described in the foregoing embodiments, or make equivalent substitutions for some technical features, and any modifications, equivalents, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A kit for acute myeloid leukemia drug sensitivity test is characterized in that: including box body (1), the top of box body (1) is rotated and is installed box board (2), fixed mounting has fixed plate (3) in box body (1), a plurality of test tube holes (4) that evenly set up are seted up at the top of fixed plate (3), four fixed column (5) that are the rectangle setting are installed to the bottom of fixed plate (3), four bottom plate (6) are installed to the bottom of fixed column (5), pushing mechanism is installed to the lateral part of box board (2), the last installation of pushing mechanism is located be located fixed plate (3) with clamping mechanism between bottom plate (6), adsorption equipment is installed to the bottom of box body (1), adsorption equipment with pushing mechanism cooperates the installation.

2. The kit for acute myeloid leukemia drug sensitivity test according to claim 1, wherein: pushing mechanism including rotate install in two of box board (2) bottom link up pole (26), two the bottom of linking up pole (26) is all rotated and is installed locating lever (16), two equal slip on locating lever (16) has cup jointed locating frame (17), two the lateral part of locating frame (17) all install in on one side inner wall of box body (1), two connecting rod (18) are installed to the bottom of locating lever (16), installation pole (19) are installed to the lateral part of connecting rod (18), installation pole (19) with adsorption apparatus connects, the top of installation pole (19) is installed and is compressed tightly the unit, compress tightly the unit with clamping mechanism connects.

3. The kit for acute myeloid leukemia drug sensitivity test according to claim 2, wherein: compress tightly the unit including install in slide bar (10) on box body (1) one side inner wall, slide bar (10) are gone up and are slided and have been cup jointed horizontal pole (7), two stopper (11) are installed, two lateral part that stopper (11) are close to each other installs gag lever post (12), sliding and having been cup jointed compact heap (14) on gag lever post (12), the bottom of compact heap (14) is rotated and is installed pull rod (15), the bottom of pull rod (15) rotate install in on the top of installation pole (19), spacing spring (13) have been cup jointed on gag lever post (12), the both ends of spacing spring (13) install respectively in compact heap (14) on the lateral part that stopper (11) are close to each other, horizontal pole (7) with clamping mechanism connects.

4. The kit for acute myeloid leukemia drug sensitivity test according to claim 3, wherein: clamping mechanism is including installing in a plurality of riser (8) of horizontal pole (7) lateral part, and is a plurality of arc wall (9) have all been seted up to the lateral part of riser (8), and is a plurality of arc wall (9) are respectively with a plurality of the position of test tube hole (4) is corresponding.

5. The kit for acute myeloid leukemia drug sensitivity test according to claim 2, wherein: adsorption equipment is including installing in removal frame (20) of installation pole (19) one end, four piston rods (21), four are installed to the bottom of removing frame (20) piston rod (22) are all installed to piston rod (21) bottom, four absorption holes have been seted up on the bottom side inner wall of box body (1), four equal fixed mounting has piston cover (23), four in the absorption hole piston (22) respectively slidable mounting in four in piston cover (23), four sucking disc (24) that are linked together are all installed to the bottom of piston cover (23), the lateral part installation limit bit cell of removing frame (20), four stabilizer blades (25) are installed to the bottom of box body (1), four stabilizer blade (25) and four the position of sucking disc (24) is corresponding.

6. The kit for acute myeloid leukemia drug sensitivity test according to claim 5, wherein: spacing unit is including seting up in spacing hole on box body (1) one side inner wall, sliding mounting has straight-bar (28) in the spacing hole, draw-in groove (27) have been seted up to the lateral part of removing frame (20), straight-bar (28) are close to the one end of piston rod (21) extends to in draw-in groove (27), L shape kelly (31) are installed to the bottom of straight-bar (28), L shape kelly (31) with the position of draw-in groove (27) is corresponding, the lateral part of L shape kelly (31) pass through fixed spring (30) with the interior wall connection of box body (1).

7. The kit for acute myeloid leukemia drug sensitivity test according to claim 6, wherein: one end of the straight rod (28) far away from the piston (22) extends out of the box body (1) and is provided with a handle (29).

8. The kit for acute myeloid leukemia susceptibility testing according to claim 1, wherein: the top of the box plate (2) is provided with a handle.