CN115739408A - Full-automatic chenodeoxycholic acid apparatus for producing - Google Patents
Full-automatic chenodeoxycholic acid apparatus for producing Download PDFInfo
- Publication number
- CN115739408A CN115739408A CN202211564275.9A CN202211564275A CN115739408A CN 115739408 A CN115739408 A CN 115739408A CN 202211564275 A CN202211564275 A CN 202211564275A CN 115739408 A CN115739408 A CN 115739408A
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- Prior art keywords
- rod
- chenodeoxycholic acid
- automatic
- full
- extrusion cylinder
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- RUDATBOHQWOJDD-UHFFFAOYSA-N (3beta,5beta,7alpha)-3,7-Dihydroxycholan-24-oic acid Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)CC2 RUDATBOHQWOJDD-UHFFFAOYSA-N 0.000 title claims abstract description 56
- RUDATBOHQWOJDD-BSWAIDMHSA-N chenodeoxycholic acid Chemical compound C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)CC1 RUDATBOHQWOJDD-BSWAIDMHSA-N 0.000 title claims abstract description 56
- 229960001091 chenodeoxycholic acid Drugs 0.000 title claims abstract description 56
- 238000001125 extrusion Methods 0.000 claims abstract description 58
- 238000004519 manufacturing process Methods 0.000 claims abstract description 22
- 239000002994 raw material Substances 0.000 claims abstract description 6
- 230000000670 limiting effect Effects 0.000 claims description 27
- 230000005540 biological transmission Effects 0.000 claims description 15
- 238000007789 sealing Methods 0.000 claims description 8
- 238000005192 partition Methods 0.000 claims description 6
- 239000000463 material Substances 0.000 abstract description 7
- 239000011259 mixed solution Substances 0.000 description 14
- 230000000694 effects Effects 0.000 description 13
- 239000007788 liquid Substances 0.000 description 13
- 230000008878 coupling Effects 0.000 description 10
- 238000010168 coupling process Methods 0.000 description 10
- 238000005859 coupling reaction Methods 0.000 description 10
- 238000001914 filtration Methods 0.000 description 9
- 230000000903 blocking effect Effects 0.000 description 6
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 6
- 238000005119 centrifugation Methods 0.000 description 4
- 235000012000 cholesterol Nutrition 0.000 description 3
- 239000013078 crystal Substances 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 210000000941 bile Anatomy 0.000 description 2
- 230000018044 dehydration Effects 0.000 description 2
- 238000006297 dehydration reaction Methods 0.000 description 2
- KXGVEGMKQFWNSR-LLQZFEROSA-N deoxycholic acid Chemical compound C([C@H]1CC2)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)[C@@H](O)C1 KXGVEGMKQFWNSR-LLQZFEROSA-N 0.000 description 2
- 229960003964 deoxycholic acid Drugs 0.000 description 2
- KXGVEGMKQFWNSR-UHFFFAOYSA-N deoxycholic acid Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)C(O)C2 KXGVEGMKQFWNSR-UHFFFAOYSA-N 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000002093 peripheral effect Effects 0.000 description 2
- 230000000630 rising effect Effects 0.000 description 2
- 235000017166 Bambusa arundinacea Nutrition 0.000 description 1
- 235000017491 Bambusa tulda Nutrition 0.000 description 1
- 241001330002 Bambuseae Species 0.000 description 1
- 235000015334 Phyllostachys viridis Nutrition 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 239000011425 bamboo Substances 0.000 description 1
- 239000003833 bile salt Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 239000000693 micelle Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Images
Abstract
The invention discloses a full-automatic chenodeoxycholic acid production device which comprises a shell, wherein a support is connected in the shell in a sliding mode, a filter cartridge is connected to the support in a rotating mode, a driving mechanism used for controlling the lifting of the support and the centrifugal rotation of the filter cartridge is arranged in the shell, and a passive feeding mechanism is arranged above the filter cartridge; the passive feeding mechanism comprises an extrusion cylinder and a plugging rod for controlling the opening and closing of an outlet of the extrusion cylinder, a raw material bin is arranged in the extrusion cylinder, the extrusion cylinder is arranged above the filter cylinder, and the plugging rod controls the opening and closing of the outlet of the extrusion cylinder based on the distance between the extrusion cylinder and the filter cylinder. According to the full-automatic chenodeoxycholic acid production device, when the surplus of chenodeoxycholic acid in the filter cylinder is small, the material in the extrusion cylinder is automatically added into the filter cylinder, so that the discharge amount of the chenodeoxycholic acid is close to the preset value every time.
Description
Technical Field
The invention relates to the field of chenodeoxycholic acid production, and in particular relates to a full-automatic chenodeoxycholic acid production device.
Background
Chenodeoxycholic Acid (CDCA) mainly has the effect of reducing the saturation of cholesterol in bile, after a patient takes the CDCA (when the CDCA accounts for 70% of bile salt in the bile), lipid is recovered to be in a micelle state, and the cholesterol is in an unsaturated state, so that the cholesterol in calculus is dissolved and shed, and the chenodeoxycholic acid is colorless acicular crystals in a natural state, is almost insoluble in water and is easily soluble in an organic solvent.
If the grant publication number is CN 216457323U, the grant date is 2022.05.10, the title is "chenodeoxycholic acid filtering and separating device" granted patent, including containing cylinder, feeder hopper and filter screen, the radial outer wall of filter screen and the inner chamber wall sliding fit of containing cylinder, the bottom of feeder hopper and the open end sliding plug-in of containing cylinder, the inside of containing cylinder is provided with fixed establishment, fixed establishment includes the adjustable ring with containing cylinder rotation installation, the radial inner wall fixed mounting of adjustable ring has the stopper, the radial outer wall fixed mounting of feeder hopper bottom has the guide block, the inside fixed mounting of containing cylinder has the torsional spring. This patent is through pegging graft the back with feeder hopper and containing cylinder, carries on spacingly to the guide block by rotating the adjustable ring and by the stopper, can pour the stoste into by the feeder hopper this moment and filter through straining a section of thick bamboo, accomplishes and adjusts the stopper through rotating after filtering, then takes the feeder hopper out by the containing cylinder inner chamber, can disinfect the feeder hopper this moment to secondary simple to use is practical.
The shortcoming of prior art lies in, centrifugal filtration is automatic continuous type feeding, thereby the problem that this brought is that, thereby the number of the unable accurate acquisition centrifugation material of current sensor feeds back to feed mechanism when the centrifugation is rotatory, and when the centrifugation putty was serious, thereby can lead to centrifugal equipment class material to pile up in a large number and lead to the emergence of burn out phenomenon.
Disclosure of Invention
The invention aims to provide a full-automatic chenodeoxycholic acid production device, which aims to overcome the defects in the prior art.
In order to achieve the above purpose, the invention provides the following technical scheme:
a full-automatic chenodeoxycholic acid production device comprises a shell, wherein a support is connected in the shell in a sliding mode, a filter cartridge is connected to the support in a rotating mode, a driving mechanism used for controlling the lifting of the support and the centrifugal rotation of the filter cartridge is arranged in the shell, and a passive feeding mechanism is arranged above the filter cartridge;
the passive feeding mechanism comprises an extrusion cylinder and a plugging rod for controlling the opening and closing of an outlet of the extrusion cylinder, a raw material bin is arranged in the extrusion cylinder, the extrusion cylinder is arranged above the filter cylinder, and the plugging rod controls the opening and closing of the outlet of the extrusion cylinder based on the distance between the extrusion cylinder and the filter cylinder.
The full-automatic chenodeoxycholic acid production device is characterized in that a partition plate is fixedly connected in the extrusion cylinder, and a drainage hole is formed in the transmission rod.
According to the full-automatic chenodeoxycholic acid production device, the sealing plate is fixedly connected to the plugging rod.
According to the full-automatic chenodeoxycholic acid production device, the extrusion cylinder is provided with the pressure sensor, and the pressure sensor is electrically connected with the driving mechanism.
Foretell full-automatic chenodeoxycholic acid apparatus for producing, actuating mechanism includes driving motor and the first drive wheel of being connected with the driving motor output, the driving motor rigid coupling in diapire in the casing, the rigid coupling threaded rod on the first drive wheel, the threaded rod with support threaded connection.
Foretell full-automatic chenodeoxycholic acid apparatus for producing, actuating mechanism still includes the secondary drive wheel, the secondary drive wheel with the diapire rotates in the casing to be connected, first drive wheel with through belt drive between the secondary drive wheel, cartridge filter week side rigid coupling has the sleeve, the sleeve with the rigid coupling has the transfer line between the secondary drive wheel.
The transmission rod comprises a first rod body and a second rod body, the first rod body is fixedly connected to the second transmission wheel, the second rod body is fixedly connected to the sleeve, and the first rod body is connected with the second rod body in a sliding mode.
The full-automatic chenodeoxycholic acid production device is characterized in that the second rod body is fixedly connected with a limiting block, and the first rod body is provided with a limiting groove matched with the limiting block.
Foretell full-automatic chenodeoxycholic acid apparatus for producing, sleeve bottom circumference is provided with a plurality of through-holes.
In the full-automatic chenodeoxycholic acid production device, the support is fixedly connected with a collecting tank, the collecting tank is positioned below the sleeve and surrounds the sleeve, and a guide plate is arranged in the collecting tank.
In the technical scheme, the full-automatic chenodeoxycholic acid production device provided by the invention is characterized in that the sealing rod is arranged in the extrusion cylinder, and sufficient mixed solution is added in the extrusion cylinder in advance, when the chenodeoxycholic acid crystal amount in the filter cylinder is small, the lifting height of the filter cylinder and the support is higher by the driving mechanism, so that the upper surface of the support is contacted and extruded with two ends of the sealing rod, the sealing rod is integrally moved upwards, therefore, the sealing effect of the bottom end of the sealing rod on the outlet position of the extrusion cylinder is relieved, the material in the extrusion cylinder is automatically added into the filter cylinder, the passive addition of the material is realized, and the discharge amount of the chenodeoxycholic acid at each time is close to the preset value.
Drawings
In order to more clearly illustrate the embodiments of the present application or technical solutions in the prior art, the drawings needed to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments described in the present invention, and other drawings can be obtained by those skilled in the art according to the drawings.
FIG. 1 is a schematic diagram of an overall structure provided in an embodiment of the present invention;
FIG. 2 is a schematic diagram of a side view configuration provided in accordance with an embodiment of the present invention;
FIG. 3 is a schematic cross-sectional view taken at a-a in FIG. 2;
FIG. 4 is an enlarged view of a portion of the structure at A in FIG. 3;
FIG. 5 is an enlarged view of a portion of the structure at B in FIG. 3;
fig. 6 is an enlarged view of a portion of the structure at C in fig. 3.
Description of reference numerals:
1. a housing; 1.1, a chute; 2. a centrifugal filtration mechanism; 3. a filter cartridge; 3.1, a frame; 3.2, a mesh area; 4. a support; 4.1, a circular ring section; 4.2, a sliding connection section; 5. a drive mechanism; 6. an extrusion cylinder; 6.1, a second connecting ring; 6.2, avoiding the area; 6.3, an upper cavity; 6.4, a lower cavity body; 7. a hinged seat; 8. a connecting rod; 8.1, a first connecting ring; 9. a cover plate; 10. a drive motor; 11. a first drive pulley; 12. a threaded rod; 13. a second transmission wheel; 14. a sleeve; 15. a transmission rod; 15.1, a first rod body; 15.2, a second rod body; 15.3, a limiting block; 15.4, a limiting groove; 15.4.1, a guide section; 15.4.2, a limiting section; 16. a connecting shaft; 17. a through hole; 18. collecting tank; 19. a baffle; 20. a storage area; 25. a second spring; 26. a plugging rod; 26.1, plugging the disc; 26.2, an abutting section; 27. sealing plates; 28. a first spring; 29. a pressure sensor; 30. a drainage hole; 31. a partition plate; 32. a passive feeding mechanism.
Detailed Description
In order to make those skilled in the art better understand the technical solution of the present invention, the present invention will be further described in detail with reference to the accompanying drawings.
Referring to fig. 1 to 6, an embodiment of the present invention provides a full-automatic chenodeoxycholic acid production apparatus, including a housing 1, wherein a support 4 is slidably connected in the housing 1, a filter cartridge 3 is rotatably connected on the support 4, a driving mechanism 5 for controlling the support to ascend and descend and the filter cartridge 3 to centrifugally rotate is arranged in the housing 1, and a passive feeding mechanism 32 is arranged above the filter cartridge 3; the passive feeding mechanism 32 comprises an extrusion cylinder 6 and a blocking rod 26 for controlling the opening and closing of the outlet of the extrusion cylinder 6, a raw material bin is arranged in the extrusion cylinder 6, the extrusion cylinder 6 is arranged above the filter cylinder 3, and the blocking rod 26 controls the opening and closing of the outlet of the extrusion cylinder 6 based on the distance between the extrusion cylinder 6 and the filter cylinder 3.
Specifically, the casing 1 is a cylindrical barrel body with a hollow inner part, the support 4 comprises a circular ring section 4.1 and a sliding connection section 4.2 which are connected, a sliding chute 1.1 matched with the sliding connection section 4.2 is arranged on the inner side wall of the casing 1, so that the support 4 can slide vertically along the casing 1, the filter cartridge 3 comprises a frame 3.1 and a net-shaped area 3.2 arranged at the bottom of the frame 3.1, the top end of the frame 3.1 is rotatably connected with the circular ring section 4.1, the cross section of the net-shaped area 3.2 is arc-shaped to increase the filtering area, the cross section of the bottom end of the extrusion cylinder 6 is arc-shaped matched with the net-shaped area 3.2, the bottom end of the extrusion cylinder is provided with an outlet through which mixed liquid can pass, the plugging rod 26 is T-shaped, the two ends of the plugging rod are provided with the butting sections 26.2, in the extrusion state, the butting section 26.2 is butted with the sliding connection section 4.2, and the bottom end of the T-shaped plugging disc 26.1 matched with the outlet in size, the two ends of the T-shaped horizontal section of the plugging rod 26 are all arranged on the side wall of the extrusion container 6 in a penetrating manner, the horizontal section is provided with a vertical movable space on the side wall of the extrusion container 6, the space is an avoidance area 6.2, meanwhile, a first spring 28 is arranged between the plugging rod 26 and the side wall of the extrusion container 6, one end of the first spring 28 is fixedly connected with the inner top wall of the avoidance space 6.2, the other end of the first spring is fixedly connected with the upper surface of the plugging rod 26, a hinged seat 7 is fixedly connected on the shell 1, the extrusion container 6 is hinged with the hinged seat 7 through a connecting rod 8, a cover plate 9 is further hinged on the hinged seat 7, when the cover plate 9 is closed, the extrusion container 6 is positioned under the cover plate 9, the arrangement is used for the purpose that the driving mechanism 5 drives the filter cartridge 3 and the chenodeoxycholic acid mixed solution in the filter cartridge 3 to rotate at a high speed, part of the chenodeoxycholic acid mixed solution can be actively removed in a centrifugal mode, and the filter cartridge 3 is driven to synchronously ascend during rotation, because the recipient 6 is fixed by apron 9, make inside chenodeoxycholic acid crystal of cartridge filter 3 and the extrusion of recipient 6 below, further get rid of the inside liquid of chenodeoxycholic acid through extruded mode, not only accelerated the filter speed, and the filter effect has been improved, when the surplus of the inside chenodeoxycholic acid of cartridge filter 3 is less, the distance that the cartridge filter 3 moved up will increase, when sliding connection section 4.2 and butt section 26.2 contact and extrude, can make shutoff pole 26 shift up wholly, therefore, the sealed effect of shutoff pole 26 bottom to 6 exit position of recipient is relieved, thereby make inside material automatic addition of recipient 6 inside cartridge filter 3, realize the passive form of material and add, make the discharge capacity of chenodeoxycholic acid at every turn all be close to the default.
Further, a partition plate 31 is fixedly connected in the extrusion cylinder 6, a drainage hole 30 is formed in the plugging plate 26, specifically, the partition plate 31 is in a circular ring shape, the outer ring is fixedly connected with the inner wall of the extrusion container 6, the inner ring is sleeved on the vertical section of the plugging rod 26 in a sliding way, the raw material bin inside the extrusion container 6 is divided into an upper cavity 6.3 and a lower cavity 6.4 by a clapboard 31, the number of the drainage holes 30 is not less than two, and preferably six, a plurality of drainage holes 30 are arranged in a circumferential array around the vertical section of the plugging rod 26, two ends of each drainage hole 30 are respectively positioned in the upper cavity 6.3 and the lower cavity 6.4, the effect of this arrangement is that, in the initial state, the blocking rod 26 is at the lowest position under the action of the mixed solution, its own weight and the first spring 28, that is, the outlet of the container 6 is blocked by the blocking disc 26.1, the mixed solution in the upper chamber 6.3 will flow into the lower chamber 6.4 through the drainage hole 30, and the lower chamber 6.4 will be completely filled, when the sliding connection section 4.2 contacts and extrudes the abutting section 26.2, the blocking rod 26 is driven to move upwards, the outlet at the bottom end of the drainage hole 30 enters the upper cavity 6.3 from the lower cavity 6.4, the partition plate 31 is sealed and attached to the vertical section of the blocking rod 26, thereby leading the upper cavity 6.3 and the lower cavity 6.4 not to be communicated, namely leading the mixed solution in the upper cavity 6.3 not to enter the lower cavity 6.4, at the same time, the original mixed solution in the lower cavity 6.4 will flow into the filter cartridge 3 through the outlet, because the mixed solution in the lower cavity 6.4 flows to the filter cartridge 3 and simultaneously the solution in the upper cavity 6.3 does not flow to the lower cavity 6.4, the amount of mixed solution flowing into the filter cartridge 3 at a time (i.e., the amount added at a time is the volume in the lower chamber 6.4) is fixed, thereby achieving quantitative addition of the mixed solution.
Further, the rigid coupling has the closing plate 27 on the shutoff pole 26, and is concrete, and closing plate 27 has two, and equal rigid coupling in the upper surface of shutoff pole 26, and hug closely in the inboard of dodging regional 6.2 and recipient 6, so the effect that sets up lies in, owing to dodge regional 6.2 and can be with raw material storehouse and 1 inner chamber intercommunication of casing, closing plate 27 can be blockked up dodging regional 6.2 to can avoid mixed solution to enter into inside the casing 1.
Further, the extrusion cylinder 6 is provided with a pressure sensor 29, the pressure sensor 29 is electrically connected to the driving mechanism 5, specifically, the pressure sensor 29 has a function of time delay control, which is not described in detail in the prior art, and is fixedly connected to the outer side wall of the extrusion cylinder 6 and located on the movement stroke of the plugging rod 26, so that the plugging rod 26 contacts and extrudes the pressure sensor 29 when moving upward, when the pressure sensor 29 senses a pressure value, the driving mechanism 5 is preferentially controlled to stop, then the driving mechanism 5 is controlled to rotate reversely after a time delay of 3-5s (all mixed solution in the lower cavity 6.4 is added into the filter cylinder 3 within 3-5 s), and the filter cylinder 3 returns to the initial position, and after the filter cylinder 3 returns to the initial position, the driving motor 5 is controlled to rotate reversely again, and the step of centrifugal extrusion of chenodeoxycholic acid is repeated.
Further, when actuating mechanism 5 reverses, can make to separate between sliding connection section 4.2 and the butt section 26.2, also the effort of sliding connection section 4.2 to shutoff pole 26 can disappear, shutoff pole 26 can move down this moment for shutoff dish 26.1 is stopped up the export, and meanwhile, the bottom export of drainage hole 30 can move down to inside cavity 6.4 down, thereby can make the inside mixed solution of upper cavity 6.3 add to cavity 6.3 down inside again, realize cavity 6.4's automatic filling down.
Preferably, actuating mechanism 5 includes driving motor 10 and the first drive wheel 11 of being connected with driving motor 10 output, driving motor 10 rigid coupling in diapire in the casing 1, rigid coupling threaded rod 12 on the first drive wheel 11, threaded rod 12 with 4 threaded connection of support, it is concrete, set up the screw hole with 12 looks adaptations of threaded rod on the sliding connection section 4.2 of support 4, so set up the effect lie in, open driving motor 10, driving motor 10 drives the first drive wheel 11 of its output and rotates to it is rotatory to drive threaded rod 12, under threaded rod 12 and threaded hole threaded connection's effect, can provide support 4 along the required power of 1 inner wall vertical slip of casing.
Further, the driving mechanism 5 further includes a second driving wheel 13, the second driving wheel 13 is rotatably connected with the inner bottom wall of the housing 1, the first driving wheel 11 is in belt transmission with the second driving wheel 13, a sleeve 14 is fixedly connected to the peripheral side of the filter cartridge 3, a transmission rod 15 is fixedly connected between the sleeve 14 and the second driving wheel 13, specifically, the bottom end of the second driving wheel 13 is provided with a connecting shaft 16, the bottom end of the connecting shaft 16 is rotatably connected with the inner bottom wall of the housing 1 through a bearing, and the sleeve 14 surrounds the outside of the filter cartridge 3 to prevent splashing of liquid, so that the second driving wheel 13 can be driven to rotate synchronously under the action of the belt when the first driving wheel 11 rotates, so as to drive the sleeve 14 and the filter cartridge 3 to rotate synchronously, when the filter cartridge 3 rotates, the chenodeoxycholic acid inside the filter cartridge can be driven to rotate, so as to carry out centrifugal dehydration on the chenodeoxycholic acid, and under the centrifugal action of centrifugation, the chenodeoxycholic acid inside the filter cartridge 3 gradually increases along the radial direction of the filter cartridge 3, so that the filter cartridge shows the deoxycholic acid at the central position of the filter cartridge 3 is lower than the peripheral deoxycholic acid, so as to be adapted to the position of the corresponding position of the squeezing cylinder 6, thereby reducing the squeezing dead angle of the squeezing cylinder 6, and the squeezing cylinder 6 is almost no squeezing dead hole of the chenodeoxycholic acid squeezing cylinder 3.
As a preferred embodiment, the transmission rod 15 includes a first rod body 15.1 and a second rod body 15.2, the first rod body 15.1 is fixedly connected to the second transmission wheel 13, the second rod body 15.2 is fixedly connected to the sleeve 14, the first rod body 15.1 is slidably connected to the second rod body 15.2, the second rod body 15.2 is fixedly connected to a limiting block 15.3, the first rod body 15.1 is provided with a limiting groove 15.4 adapted to the limiting block 15.3, specifically, the first rod body 15.1 is fixedly connected to the upper surface of the second transmission wheel 13, the second rod body 15.2 is fixedly connected to the lower surface of the sleeve 14, the other ends of the first rod body and the second rod body are slidably connected, the limiting block 15.3 is fixedly connected to the outer surface of the second rod body 15.2 and located at an end close to the sleeve 14, the length of the first rod body is smaller than the rising height of the filter cartridge 3, and the setting is used for having three strokes when the filter cartridge 3 rises, one of which is used when the second transmission rod 15 drives the first rod body 15.1 to rotate, and under the limiting action of the limiting block 15.3 and the limiting groove 15.4, the second rod body 15.2 and the sleeve 14 can be driven to rotate, so as to drive the filter cartridge 3 to rotate, because the second rod body 15.2 and the sleeve 14 continuously rise under the action of the driving mechanism 5, namely, the stroke of centrifugal filtration while rising, secondly, when the filter cartridge 3 rises, the limiting block 15.3 can slide upwards along the limiting groove 15.4, when the limiting block 15.3 is separated from the limiting groove 15.4, namely, the kinetic energy of the first rod body 15.1 during rotation can not be continuously transmitted to the second rod body 15.2, the sleeve 14 and the filter cartridge 3 can continuously rotate for a period of time under the action of inertia, and then can automatically stop rotating, namely, the stroke of stopping rotation, thirdly, under the threaded connection action of the threaded rod 12 and the support 4, the filter cartridge 3 can continuously rise, so as to enable the chenolic acid in the filter cartridge 3 and the extrusion stroke of the extrusion cylinder 6, thereby realizing the centrifugal filtration and the extrusion dehydration of the chenodeoxycholic acid. The three strokes are a complete centrifugal dewatering extrusion stroke, and after the three strokes are finished, the driving mechanism 5 rotates reversely to reset the whole device and carry out the next process.
Furthermore, the area of the top end of the limiting groove 15.4 is larger than the area of the bottom end, specifically, the limiting groove 15.4 includes the guide section 15.4.1 and the limiting section 15.4.2, and the effect of the arrangement is that when the second rod body 15.2 drives the limiting block 15.3 to descend, the bottom end of the limiting block 15.3 preferentially contacts with the inner wall of the guide section 15.4.1, then slides downwards along the inner wall of the guide section 15.4.1, and finally falls into the limiting section 15.4.2, so as to facilitate the resetting of the second rod body 15.2.
Preferably, 14 bottom circumferences of sleeve are provided with a plurality of through-holes 17, the rigid coupling has collecting vat 18 on the support 4, collecting vat 18 is located 14 below of sleeve, and will sleeve 14 surrounds, and is concrete, and collecting vat 18 rigid coupling in sliding connection section 4.2 below, and through-hole 17 sets up in 14 bottom border position of sleeve, and circumference array sets up, and the effect that so sets up lies in, and at cartridge filter 3 pivoted in-process, chenodeoxycholic acid will get rid of the sleeve 14 inside wall in the mesh of cartridge filter 3, through the cushioning effect of sleeve 14, then along with sleeve 14 inside wall landing to through-hole 17 position, flow to collect in the groove 18 through-hole 17 again and collect in unison.
Preferably, be provided with guide plate 19 in the collecting vat 18, specifically, guide plate 19 is the round platform form, and guide plate 19 and collecting vat 18 lateral wall's junction top is storage area 20, and the effect that so sets up lies in, and the liquid that falls via through-hole 17 can be preferred to contact with the surface of guide plate 19, then slides along guide plate 19 surface and falls storage area 20 and keep in.
As a preferred embodiment, the squeezing barrel 6 and the connecting rod 8 are elastically connected, specifically, one end of the connecting rod 8 is provided with a first connecting ring 8.1, the other end of the connecting rod is hinged to the hinge seat 7, the top of the squeezing barrel 6 is fixedly connected with a second connecting ring 6.1 in the circumferential direction, a second spring 25 is arranged between the first connecting ring 8.1 and the second connecting ring 6.1, the number of the second springs 25 should be no less than four, and preferably six, one end of the second spring 25 is fixedly connected to the top end of the first connecting ring 8.1, and the other end of the second spring is fixedly connected to the bottom end of the second connecting ring 6.1, so that in an initial state, the squeezing barrel 6 is located above the filtering barrel 3, by adding the mixed solution to be filtered into the squeezing barrel 6, when the liquid falls on the inner wall of the squeezing barrel 6, under the action of the second spring 25, the acting force applied when the mixed liquid falls can be buffered, so as to avoid splashing when the mixed liquid falls, and when the mixed liquid is added, the squeezing barrel 6 is slightly shaken under the action of the second spring 25, so as to play a role of fixing the cover plate to prevent the mixed liquid from splashing when the squeezing barrel 6 is added, and the subsequent mixed liquid is added, so as to provide a beneficial condition, the mixed liquid, and the mixed liquid can be added, and the mixed liquid can be beneficial for providing a vibration cover plate 9, and the mixing cover plate, and can be a good for the squeezing barrel 6.
Further, after chenodeoxycholic acid finishes filtering, open apron 9, in opening apron 9, second spring 25's elasticity is released, consequently, the extrusion cylinder 6 produces the vibration under the effect of second spring 25 elasticity, and wholly can shift up a section distance in the vibration, make extrusion cylinder 6 keep away from chenodeoxycholic acid, and in the time of extrusion cylinder 6 vibration, can shake the chenodeoxycholic acid who falls and adhere to 6 lower surfaces of extrusion cylinder, make the chenodeoxycholic acid who shakes and fall once more to the cartridge filter 3 in, realized the clear function of extrusion cylinder 6 passive form.
Further, when chenodeoxycholic acid inside the filter cylinder 3 needs to be taken out, only the connecting rod 8 needs to be rotated to move the extruding cylinder 6 to the position of the cover plate 9, so that a sufficient space is provided for taking out the chenodeoxycholic acid.
While certain exemplary embodiments of the present invention have been described above by way of illustration only, it will be apparent to those of ordinary skill in the art that the described embodiments may be modified in various different ways without departing from the spirit and scope of the present invention. Accordingly, the drawings and description are illustrative in nature and are not to be construed as limiting the scope of the invention.
Claims (10)
1. A full-automatic chenodeoxycholic acid production device comprises a shell, and is characterized in that a support is connected in the shell in a sliding mode, a filter cartridge is connected to the support in a rotating mode, a driving mechanism used for controlling the support to ascend and descend and the filter cartridge to rotate centrifugally is arranged in the shell, and a passive feeding mechanism is arranged above the filter cartridge;
the passive feeding mechanism comprises an extrusion cylinder and a plugging rod for controlling the opening and closing of an outlet of the extrusion cylinder, a raw material bin is arranged in the extrusion cylinder, the extrusion cylinder is arranged above the filter cylinder, and the plugging rod controls the opening and closing of the outlet of the extrusion cylinder based on the distance between the extrusion cylinder and the filter cylinder.
2. The full-automatic chenodeoxycholic acid production device according to claim 1, wherein a partition plate is fixedly connected in the extrusion cylinder, and a drainage hole is formed in the transmission rod.
3. The full-automatic chenodeoxycholic acid production device according to claim 1, wherein a sealing plate is fixedly connected to the plugging rod.
4. The full-automatic chenodeoxycholic acid production device according to claim 1, wherein a pressure sensor is arranged on the extrusion cylinder, and the pressure sensor is electrically connected with the driving mechanism.
5. The full-automatic chenodeoxycholic acid production device of claim 1, wherein the driving mechanism comprises a driving motor and a first driving wheel connected with an output end of the driving motor, the driving motor is fixedly connected with the inner bottom wall of the shell, a threaded rod is fixedly connected to the first driving wheel, and the threaded rod is in threaded connection with the support.
6. The full-automatic chenodeoxycholic acid production device of claim 5, wherein the driving mechanism further comprises a second driving wheel, the second driving wheel is rotatably connected with the inner bottom wall of the shell, the first driving wheel and the second driving wheel are driven by a belt, a sleeve is fixedly connected on the periphery of the filter cartridge, and a transmission rod is fixedly connected between the sleeve and the second driving wheel.
7. The apparatus of claim 6, wherein the transmission rod comprises a first rod and a second rod, the first rod is fixedly connected to the second transmission wheel, the second rod is fixedly connected to the sleeve, and the first rod and the second rod are slidably connected.
8. The full-automatic chenodeoxycholic acid production device of claim 7, wherein a limiting block is fixedly connected to the second rod body, and a limiting groove matched with the limiting block is formed in the first rod body.
9. The full-automatic chenodeoxycholic acid production device of claim 6, wherein the bottom end of the sleeve is circumferentially provided with a plurality of through holes.
10. The full-automatic chenodeoxycholic acid production device according to claim 9, wherein a collecting tank is fixedly connected to the support, the collecting tank is located below the sleeve and surrounds the sleeve, and a guide plate is arranged in the collecting tank.
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| CN202211564275.9A CN115739408B (en) | 2022-12-07 | 2022-12-07 | Full-automatic chenodeoxycholic acid apparatus for producing |
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| CN202211564275.9A CN115739408B (en) | 2022-12-07 | 2022-12-07 | Full-automatic chenodeoxycholic acid apparatus for producing |
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| CN115739408B (en) | 2024-03-29 |
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