CN115739408B - Full-automatic chenodeoxycholic acid apparatus for producing - Google Patents
Full-automatic chenodeoxycholic acid apparatus for producing Download PDFInfo
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- CN115739408B CN115739408B CN202211564275.9A CN202211564275A CN115739408B CN 115739408 B CN115739408 B CN 115739408B CN 202211564275 A CN202211564275 A CN 202211564275A CN 115739408 B CN115739408 B CN 115739408B
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- rod
- fixedly connected
- extrusion
- chenodeoxycholic acid
- filter cartridge
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- RUDATBOHQWOJDD-UHFFFAOYSA-N (3beta,5beta,7alpha)-3,7-Dihydroxycholan-24-oic acid Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)CC2 RUDATBOHQWOJDD-UHFFFAOYSA-N 0.000 title claims abstract description 53
- RUDATBOHQWOJDD-BSWAIDMHSA-N chenodeoxycholic acid Chemical compound C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)CC1 RUDATBOHQWOJDD-BSWAIDMHSA-N 0.000 title claims abstract description 53
- 229960001091 chenodeoxycholic acid Drugs 0.000 title claims abstract description 53
- 238000001125 extrusion Methods 0.000 claims abstract description 79
- 230000007246 mechanism Effects 0.000 claims abstract description 34
- 230000000903 blocking effect Effects 0.000 claims abstract description 21
- 238000004519 manufacturing process Methods 0.000 claims abstract description 19
- 239000002994 raw material Substances 0.000 claims abstract description 6
- 230000000670 limiting effect Effects 0.000 claims description 27
- 239000011259 mixed solution Substances 0.000 claims description 20
- 230000005540 biological transmission Effects 0.000 claims description 15
- 238000007789 sealing Methods 0.000 claims description 9
- 230000009471 action Effects 0.000 claims description 7
- 230000000630 rising effect Effects 0.000 claims description 3
- 239000000463 material Substances 0.000 abstract description 7
- 230000000694 effects Effects 0.000 description 12
- 239000007788 liquid Substances 0.000 description 11
- 238000001914 filtration Methods 0.000 description 8
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 6
- 238000003860 storage Methods 0.000 description 4
- 235000012000 cholesterol Nutrition 0.000 description 3
- 230000008878 coupling Effects 0.000 description 3
- 238000010168 coupling process Methods 0.000 description 3
- 238000005859 coupling reaction Methods 0.000 description 3
- 239000013078 crystal Substances 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 210000000941 bile Anatomy 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 230000018044 dehydration Effects 0.000 description 2
- 238000006297 dehydration reaction Methods 0.000 description 2
- 238000005192 partition Methods 0.000 description 2
- 235000017166 Bambusa arundinacea Nutrition 0.000 description 1
- 235000017491 Bambusa tulda Nutrition 0.000 description 1
- 241001330002 Bambuseae Species 0.000 description 1
- 235000015334 Phyllostachys viridis Nutrition 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 230000001174 ascending effect Effects 0.000 description 1
- 239000011425 bamboo Substances 0.000 description 1
- 239000003833 bile salt Substances 0.000 description 1
- 229940093761 bile salts Drugs 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- ZHCAAZIHTDCFJX-QLEQUTGBSA-N isodeoxycholic acid Chemical compound C([C@H]1C[C@H]2O)CCC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)[C@@H](O)C1 ZHCAAZIHTDCFJX-QLEQUTGBSA-N 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000693 micelle Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Abstract
The invention discloses a full-automatic chenodeoxycholic acid production device, which comprises a shell, wherein a bracket is connected in a sliding way on the shell, a filter cartridge is connected on the bracket in a rotating way, a driving mechanism for controlling the bracket to lift and the filter cartridge to centrifugally rotate is arranged in the shell, and a passive feeding mechanism is arranged above the filter cartridge; the passive feeding mechanism comprises an extrusion barrel and a blocking rod for controlling the opening and closing of an outlet of the extrusion barrel, wherein a raw material bin is arranged in the extrusion barrel, the extrusion barrel is arranged above the filter cartridge, and the blocking rod is used for controlling the opening and closing of the outlet of the extrusion barrel based on the distance between the extrusion barrel and the filter cartridge. According to the full-automatic chenodeoxycholic acid production device provided by the invention, when the residual quantity of chenodeoxycholic acid in the filter cartridge is small, the materials in the extrusion cylinder are automatically added into the filter cartridge, so that the discharge quantity of the chenodeoxycholic acid each time is close to a preset value.
Description
Technical Field
The invention relates to the field of chenodeoxycholic acid production, in particular to a full-automatic chenodeoxycholic acid production device.
Background
Chenodeoxycholic Acid (CDCA) mainly has the function of reducing the saturation of cholesterol in bile, and after a patient takes CDCA (when CDCA accounts for 70% of bile salts in bile), lipid is recovered to a micelle state, and cholesterol is in an unsaturated state, so that the cholesterol in stones is dissolved and shed, and the chenodeoxycholic acid is in a colorless needle-like crystal in a natural state, is almost insoluble in water and is easily dissolved in an organic solvent.
If the bulletin number of authorizing is CN 216457323U, the date of authorizing is 2022.05.10, the name is patent of authorizing of chenodeoxycholic acid filtering separation device, including accomodating jar, feeder hopper and filter screen, the radial outer wall of filter screen and the inner chamber wall sliding fit who accomodates the jar, the bottom of feeder hopper and the open end slip grafting of accomodating the jar, the inside of accomodating the jar is provided with fixed establishment, fixed establishment includes the adjusting ring with accomodating the jar rotation installation, the radial inner wall fixed mounting of adjusting ring has the stopper, the radial outer wall fixed mounting of feeder hopper bottom has the guide block, the inside fixed mounting who accomodates the jar has the torsional spring. This patent is through pegging graft the back with the feeder hopper with accomodate the jar, carries out spacingly to the guide block through rotating the adjusting ring and by the stopper, can pour into the stoste by the feeder hopper and filter through straining a section of thick bamboo this moment, accomplish and adjust the stopper through rotating after filtering, then take out the feeder hopper by accomodating jar inner chamber, can disinfect the feeder hopper this moment to the secondary use is simple and practical.
The prior art has the defects that centrifugal filtration is automatic continuous feeding, and the problem is that the existing sensor cannot accurately acquire the quantity of centrifugal materials during centrifugal rotation so as to feed back to a feeding mechanism, and when centrifugal blocking is serious, a large amount of centrifugal equipment materials can be accumulated so as to cause burn-in.
Disclosure of Invention
The invention aims to provide a full-automatic chenodeoxycholic acid production device which aims to solve the defects in the prior art.
In order to achieve the above object, the present invention provides the following technical solutions:
the full-automatic chenodeoxycholic acid production device comprises a shell, wherein a bracket is connected in a sliding manner in the shell, a filter cartridge is connected to the bracket in a rotating manner, a driving mechanism for controlling the bracket to lift and controlling the filter cartridge to centrifugally rotate is arranged in the shell, and a passive feeding mechanism is arranged above the filter cartridge;
the passive feeding mechanism comprises an extrusion barrel and a blocking rod for controlling the opening and closing of an outlet of the extrusion barrel, wherein a raw material bin is arranged in the extrusion barrel, the extrusion barrel is arranged above the filter cartridge, and the blocking rod is used for controlling the opening and closing of the outlet of the extrusion barrel based on the distance between the extrusion barrel and the filter cartridge.
According to the full-automatic chenodeoxycholic acid production device, the partition plate is fixedly connected in the extrusion cylinder, and the drainage hole is formed in the transmission rod.
According to the full-automatic chenodeoxycholic acid production device, the sealing plate is fixedly connected to the sealing rod.
According to the full-automatic chenodeoxycholic acid production device, the pressure sensor is arranged on the extrusion cylinder and is electrically connected with the driving mechanism.
The full-automatic chenodeoxycholic acid production device comprises a driving mechanism and a first driving wheel connected with the output end of the driving mechanism, wherein the driving motor is fixedly connected to the inner bottom wall of the shell, a threaded rod is fixedly connected to the first driving wheel, and the threaded rod is in threaded connection with the support.
The full-automatic chenodeoxycholic acid production device comprises a shell, a first driving wheel, a second driving wheel, a sleeve, a transmission rod and a driving mechanism, wherein the first driving wheel is connected with the inner bottom wall of the shell in a rotating mode, the first driving wheel and the second driving wheel are driven by a belt, the sleeve is fixedly connected to the periphery of the filter cylinder, and the transmission rod is fixedly connected between the sleeve and the second driving wheel.
The full-automatic chenodeoxycholic acid production device comprises a transmission rod, wherein the transmission rod comprises a first rod body and a second rod body, the first rod body is fixedly connected to the second transmission wheel, the second rod body is fixedly connected to the sleeve, and the first rod body is in sliding connection with the second rod body.
According to the full-automatic chenodeoxycholic acid production device, the limiting block is fixedly connected to the second rod body, and the limiting groove matched with the limiting block is formed in the first rod body.
Above-mentioned full-automatic chenodeoxycholic acid apparatus for producing, sleeve bottom circumference is provided with a plurality of through-holes.
Above-mentioned full-automatic chenodeoxycholic acid apparatus for producing, the rigid coupling has the collecting vat on the support, the collecting vat is located the sleeve below, and will the sleeve surrounds, just be provided with the guide plate in the collecting vat.
In the technical scheme, the blocking rod is arranged in the extrusion cylinder, and a sufficient amount of mixed solution is added in the extrusion cylinder in advance, when the amount of chenodeoxycholic acid crystals in the filter cylinder is small, the driving mechanism can enable the rising height of the filter cylinder and the bracket to be higher, so that the upper surface of the bracket is in contact with the two ends of the blocking rod and is extruded, and the blocking rod is enabled to move upwards integrally, therefore, the sealing effect of the bottom end of the blocking rod to the outlet position of the extrusion cylinder is relieved, materials in the extrusion cylinder are automatically added into the filter cylinder, passive addition of the materials is realized, and the discharge amount of chenodeoxycholic acid each time is close to a preset value.
Drawings
In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings that are needed in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments described in the present invention, and other drawings may be obtained according to these drawings for a person having ordinary skill in the art.
FIG. 1 is a schematic diagram of an overall structure according to an embodiment of the present invention;
FIG. 2 is a schematic side view of an embodiment of the present invention;
FIG. 3 is a schematic cross-sectional view of the structure at a-a in FIG. 2;
FIG. 4 is an enlarged schematic view of the partial structure of FIG. 3A;
FIG. 5 is an enlarged schematic view of a partial structure at B in FIG. 3;
fig. 6 is an enlarged schematic view of a partial structure at C in fig. 3.
Reference numerals illustrate:
1. a housing; 1.1, a chute; 2. a centrifugal filter mechanism; 3. a filter cartridge; 3.1, a frame; 3.2, a mesh area; 4. a bracket; 4.1, a circular ring section; 4.2, sliding connection section; 5. a driving mechanism; 6. an extrusion cylinder; 6.1, a second connecting ring; 6.2, avoiding area; 6.3, upper cavity; 6.4, lower cavity; 7. a hinge base; 8. a connecting rod; 8.1, a first connecting ring; 9. a cover plate; 10. a driving motor; 11. a first driving wheel; 12. a threaded rod; 13. a second driving wheel; 14. a sleeve; 15. a transmission rod; 15.1, a first rod body; 15.2, a second rod body; 15.3, limiting blocks; 15.4, a limit groove; 15.4.1, guide section; 15.4.2, spacing section; 16. a connecting shaft; 17. a through hole; 18. a collection tank; 19. a deflector; 20. a storage area; 25. a second spring; 26. a plugging rod; 26.1, a plugging disc; 26.2, abutment sections; 27. a sealing plate; 28. a first spring; 29. a pressure sensor; 30. drainage holes; 31. a partition plate; 32. and a passive feeding mechanism.
Detailed Description
In order to make the technical scheme of the present invention better understood by those skilled in the art, the present invention will be further described in detail with reference to the accompanying drawings.
Referring to fig. 1-6, an embodiment of the present invention provides a full-automatic chenodeoxycholic acid production device, which comprises a housing 1, wherein a support 4 is slidably connected to the housing 1, a filter cartridge 3 is rotatably connected to the support 4, a driving mechanism 5 for controlling the support to lift and centrifugally rotate the filter cartridge 3 is arranged in the housing 1, and a passive feeding mechanism 32 is arranged above the filter cartridge 3; the passive feeding mechanism 32 comprises an extrusion cylinder 6 and a blocking rod 26 for controlling the opening and closing of the outlet of the extrusion cylinder 6, a raw material bin is arranged in the extrusion cylinder 6, the extrusion cylinder 6 is arranged above the filter cylinder 3, and the blocking rod 26 controls the opening and closing of the outlet of the extrusion cylinder 6 based on the distance between the extrusion cylinder 6 and the filter cylinder 3.
Specifically, the shell 1 is a cylindrical barrel body with hollow inside, the bracket 4 comprises a circular ring section 4.1 and a sliding connection section 4.2 which are connected, a chute 1.1 which is matched with the sliding connection section 4.2 is arranged on the inner side wall of the shell 1, the bracket 4 can vertically slide along the shell 1, the filter cartridge 3 comprises a frame 3.1 and a net-shaped area 3.2 which is arranged at the bottom of the frame 3.1, the top end of the frame 3.1 is rotationally connected with the circular ring section 4.1, the cross section of the net-shaped area 3.2 is arc-shaped so as to increase the filtering area, the cross section of the bottom end of the extrusion barrel 6 is arc-shaped which is matched with the net-shaped area 3.2, the bottom end of the extrusion barrel is provided with an outlet through which mixed liquid can pass, the two ends of the plugging rod 26 are provided with abutting sections 26.2, under the extrusion state, the abutting sections 26.2 are abutted with the sliding connection section 4.2, the bottom end of the T is provided with a plugging disc 26.1 which is matched with the outlet in size, the two ends of the T-shaped horizontal section of the plugging rod 26 are all penetrated and arranged on the side wall of the extrusion cylinder 6, the horizontal section is provided with a vertical movable space on the side wall of the extrusion cylinder 6, the space is an avoidance area 6.2, meanwhile, a first spring 28 is arranged between the plugging rod 26 and the side wall of the extrusion cylinder 6, one end of the first spring 28 is fixedly connected with the inner top wall of the avoidance space 6.2, the other end of the first spring is fixedly connected with the upper surface of the plugging rod 26, the shell 1 is fixedly connected with a hinging seat 7, the extrusion cylinder 6 is hinged with the hinging seat 7 through a connecting rod 8, the hinging seat 7 is also hinged with a cover plate 9, and when the cover plate 9 is closed, the extrusion cylinder 6 is positioned under the cover plate 9, the driving mechanism 5 drives the filter cylinder 3 and chenodeoxycholic acid mixed solution in the filter cylinder 3 to rotate at a high speed, partial liquid doped with chenodeoxycholic acid can be actively removed in a centrifugal mode, and the filter cylinder 3 is driven to synchronously rise when rotating, because the extrusion barrel 6 is fixed by the cover plate 9, the chenodeoxycholic acid crystals inside the filter cylinder 3 are extruded below the extrusion barrel 6, the liquid inside the chenodeoxycholic acid is further removed through an extrusion mode, the filtering speed is increased, the filtering effect is improved, when the residual amount of the chenodeoxycholic acid inside the filter cylinder 3 is small, the upward moving distance of the filter cylinder 3 is increased, and when the sliding connection section 4.2 is contacted with the abutting section 26.2 and extruded, the blocking rod 26 is enabled to integrally move upwards, so that the sealing effect of the bottom end of the blocking rod 26 on the outlet position of the extrusion barrel 6 is relieved, the material inside the extrusion barrel 6 is automatically added into the filter cylinder 3, the passive addition of the material is realized, and the discharging amount of the chenodeoxycholic acid each time is close to a preset value.
Further, a baffle plate 31 is fixedly connected in the extrusion cylinder 6, a drainage hole 30 is arranged in the plugging plate 26, and the baffle plate 31 is in a circular ring shape, the outer ring is fixedly connected with the inner wall of the extrusion cylinder 6, the inner ring is sleeved on the vertical section of the plugging rod 26 in a sliding way, the baffle plate 31 divides the raw material bin in the extrusion cylinder 6 into an upper cavity 6.3 and a lower cavity 6.4, the drainage holes 30 are not less than two, and preferably six, a plurality of drainage holes 30 are circumferentially arranged in an array about the vertical section of the plugging rod 26, two ends of the drainage holes 30 are respectively located in the upper cavity 6.3 and the lower cavity 6.4, the effect of this arrangement is that in the initial state, the blocking rod 26 is in the lowest position under the influence of the mixed solution, its own weight and the first spring 28, i.e. the blocking disc 26.1 now blocks the outlet of the extruder vessel 6, the mixed solution in the upper chamber 6.3 will flow into the lower chamber 6.4 via the drainage aperture 30, and the lower chamber 6.4 is completely filled, when the sliding connection section 4.2 contacts with the abutting section 26.2 and is extruded, the plugging rod 26 is driven to move upwards, at the moment, the outlet at the bottom end of the drainage hole 30 enters into the upper cavity 6.3 from the lower cavity 6.4, the baffle plate 31 is sealed and attached on the vertical section of the plugging rod 26, so that the upper cavity 6.3 and the lower cavity 6.4 cannot be communicated, i.e. the mixed solution in the upper cavity 6.3 cannot enter the lower cavity 6.4, at the same time the original mixed solution in the lower chamber 6.4 will flow all the way through the outlet into the filter cartridge 3, because the mixed solution in the lower cavity 6.4 flows to the filter cartridge 3, the solution in the upper cavity 6.3 does not flow into the lower cavity 6.4, the amount of mixed solution flowing into the filter cartridge 3 at a time (i.e. the amount added at a time is the volume in the lower chamber 6.4) is thus fixed, whereby a dosing of mixed solution is achieved.
Further, the sealing plate 27 is fixedly connected to the plugging rod 26, specifically, two sealing plates 27 are fixedly connected to the upper surface of the plugging rod 26 and are tightly attached to the avoiding area 6.2 and the inner side of the extrusion cylinder 6, and the effect of the arrangement is that the avoiding area 6.2 can be communicated with the inner cavity of the shell 1, and the sealing plate 27 can plug the avoiding area 6.2, so that the mixed solution can be prevented from entering the shell 1.
Further, the pressure sensor 29 is disposed on the extrusion cylinder 6, the pressure sensor 29 is electrically connected with the driving mechanism 5, specifically, the pressure sensor 29 has a function of time delay control, which is not described in detail in the prior art, and is fixedly connected to the outer side wall of the extrusion cylinder 6 and located on the movement stroke of the plugging rod 26, so that the plugging rod 26 contacts and extrudes with the pressure sensor 29 when moving upwards, when the pressure sensor 29 senses the pressure value, it preferentially controls the driving mechanism 5 to stop, then controls the driving mechanism 5 to invert after a time delay of 3-5s (the mixed solution inside the lower cavity 6.4 in 3-5s is fully added into the filter cylinder 3), so that after the filter cylinder 3 returns to the initial position, and after returning to the initial position, the driving mechanism 5 is controlled to invert again, and the step of centrifugal extrusion of chenodeoxycholic acid is repeated.
Further, when the driving mechanism 5 is reversed, the sliding connection section 4.2 and the abutting section 26.2 are separated, that is, the acting force of the sliding connection section 4.2 on the plugging rod 26 is lost, at the moment, the plugging rod 26 moves downwards, so that the outlet is plugged by the plugging disc 26.1, and meanwhile, the outlet at the bottom end of the drainage hole 30 moves downwards to the inside of the lower cavity 6.4, so that the mixed solution in the upper cavity 6.3 is added into the inside of the lower cavity 6.3 again, and the automatic filling of the lower cavity 6.4 is realized.
Preferably, the driving mechanism 5 includes driving motor 10 and the first drive wheel 11 connected with the output of driving motor 10, driving motor 10 rigid coupling in diapire in the casing 1, the rigid coupling has threaded rod 12 on the first drive wheel 11, threaded rod 12 with support 4 threaded connection, specifically, offered the screw hole with threaded rod 12 looks adaptation on the slip section 4.2 of support 4, the effect of setting so lies in, opening driving motor 10, driving motor 10 drives the first drive wheel 11 rotation of its output to drive threaded rod 12 rotation can provide the power that support 4 slides required along casing 1 inner wall perpendicularly under the effect of threaded rod 12 and screw hole threaded connection.
Further, the driving mechanism 5 further comprises a second driving wheel 13, the second driving wheel 13 is rotationally connected with the inner bottom wall of the shell 1, the first driving wheel 11 and the second driving wheel 13 are in transmission through a belt, a sleeve 14 is fixedly connected to the circumferential side of the filter cylinder 3, a transmission rod 15 is fixedly connected between the sleeve 14 and the second driving wheel 13, specifically, the bottom end of the second driving wheel 13 is provided with a connecting shaft 16, the bottom end of the connecting shaft 16 is rotationally connected with the inner bottom wall of the shell 1 through a bearing, the sleeve 14 surrounds the outer side of the filter cylinder 3 to prevent liquid from splashing, and the effect of the arrangement is that when the first driving wheel 11 rotates, under the action of the belt, the second driving wheel 13 can be driven to synchronously rotate, so that the sleeve 14 and the filter cylinder 3 can be driven to synchronously rotate, and chenodeoxycholic acid in the filter cylinder 3 can be driven to rotate, so that centrifugal dehydration can be carried out on the chenodeoxycholic acid in the filter cylinder 3 is gradually increased along the radial direction of the filter cylinder 3, so that the chenodeoxycholic acid in the central position of the filter cylinder 3 is lower than the outer circumferential chenodeoxycholic acid, and the position of the cylindrical filter cylinder 6 can be extruded by the cylindrical extrusion tube 6 is almost not corresponding to the extrusion dead angle 6.
As a preferred embodiment, the transmission rod 15 includes a first rod 15.1 and a second rod 15.2, the first rod 15.1 is fixedly connected to the second transmission wheel 13, the second rod 15.2 is fixedly connected to the sleeve 14, the first rod 15.1 is slidably connected to the second rod 15.2, the second rod 15.2 is fixedly connected with a limiting block 15.3, the first rod 15.1 is provided with a limiting groove 15.4 adapted to the limiting block 15.3, specifically, the first rod 15.1 is fixedly connected to the upper surface of the second transmission wheel 13, the second rod 15.2 is fixedly connected to the lower surface of the sleeve 14, the other ends of the two are slidably connected to each other, the limiting block 15.3 is fixedly connected to the outer surface of the second rod 15.2, and is located at one end close to the sleeve 14, the length of which is smaller than the rising height of the filter cartridge 3, the effect of the arrangement is that when the filter cartridge 3 rises, there are three strokes, firstly, the second transmission rod 15 drives the first rod 15.1 to rotate, and under the limiting action of the limiting block 15.3 and the limiting groove 15.4, the second rod 15.2 and the sleeve 14 can be driven to rotate, so that the filter cartridge 3 is driven to rotate, and as the second rod 15.2 and the sleeve 14 continuously ascend under the action of the driving mechanism 5, namely, the ascending centrifugal filtration stroke is also adopted, secondly, when the filter cartridge 3 ascends, the limiting block 15.3 can slide upwards along the limiting groove 15.4, when the limiting block 15.3 is separated from the limiting groove 15.4, namely, the kinetic energy generated when the first rod 15.1 rotates is not continuously transmitted to the second rod 15.2, the sleeve 14 and the filter cartridge 3 continuously rotate for a period of time under the action of inertia, namely, the rotation stops, thirdly, under the action of the threaded rod 12 and the bracket 4, the filter cartridge 3 continuously ascends, so that the extrusion stroke of the chenodeoxycholic acid in the filter cylinder 3 and the extrusion cylinder 6 is realized, and the centrifugal filtration and extrusion dehydration of the chenodeoxycholic acid are realized. The three strokes are a complete centrifugal dewatering extrusion stroke, and after the three strokes are finished, the driving mechanism 5 reverses to reset the whole device and carry out the next flow.
Further, the top end area of the limiting groove 15.4 is larger than the bottom end area, specifically, that is, the limiting groove 15.4 includes a guiding section 15.4.1 and a limiting section 15.4.2, so that the limiting groove is set up in that when the second rod body 15.2 drives the limiting block 15.3 to descend, the bottom end of the limiting block 15.3 can be preferentially contacted with the inner wall of the guiding section 15.4.1, then slides downwards along the inner wall of the guiding section 15.4.1, finally falls into the limiting section 15.4.2, and is convenient for resetting of the second rod body 15.2.
Preferably, a plurality of through holes 17 are circumferentially arranged at the bottom end of the sleeve 14, a collecting groove 18 is fixedly connected to the support 4, the collecting groove 18 is located below the sleeve 14 and surrounds the sleeve 14, the collecting groove 18 is fixedly connected to the lower portion of the sliding connection section 4.2, the through holes 17 are arranged at the edge position of the bottom end of the sleeve 14 and are circumferentially arranged in an array manner, and the effect of the arrangement is that chenodeoxycholic acid can be thrown to the inner side wall of the sleeve 14 through meshes of the filter cylinder 3 in the rotating process of the filter cylinder 3, and then slides to the position of the through holes 17 along the inner side wall of the sleeve 14, and then flows into the collecting groove 18 through the through holes 17 for uniform collection.
Preferably, the collecting tank 18 is provided with a baffle 19, specifically, the baffle 19 is in a shape of a truncated cone, and a storage area 20 is disposed above a connection portion between the baffle 19 and a side wall of the collecting tank 18, so that the liquid falling down through the through hole 17 will preferentially contact with a surface of the baffle 19, and then slide down along the surface of the baffle 19 to the storage area 20 for temporary storage.
As a preferred embodiment, the extrusion cylinder 6 and the connecting rod 8 are elastically connected, specifically, one end of the connecting rod 8 is provided with a first connecting ring 8.1, the other end is hinged with the hinging seat 7, the top of the extrusion cylinder 6 is fixedly connected with a second connecting ring 6.1 in the circumferential direction, no less than four, and preferably six second springs 25 are arranged between the first connecting ring 8.1 and the second connecting ring 6.1, one end of the second spring 25 is fixedly connected with the top end of the first connecting ring 8.1, the other end is fixedly connected with the bottom end of the second connecting ring 6.1, and the effect is that in the initial state, the extrusion cylinder 6 is positioned above the filter cylinder 3, by adding the mixed solution to be filtered into the extrusion cylinder 6, when liquid falls to the inner wall of the extrusion barrel 6, under the action of the second spring 25, the acting force received when the mixed liquid falls can be buffered, so that splashing when the mixed liquid falls can be avoided, and when the mixed liquid is added, the extrusion barrel 6 can slightly shake up and down under the action of the second spring 25, the shaking can play a vibration effect, the mixed liquid can be prevented from remaining on the inner wall of the extrusion barrel 6, after the mixed liquid is added, the cover plate 9 is covered, the cover plate 9 downwards presses the extrusion barrel 6, and the second spring 25 is synchronously compressed, so that the position of the extrusion barrel 6 can be fixed, and favorable conditions are provided for subsequent extrusion.
Further, after the chenodeoxycholic acid is filtered, the cover plate 9 is opened, and the elastic force of the second spring 25 is released while the cover plate 9 is opened, so that the extrusion barrel 6 vibrates under the elastic force of the second spring 25, and the whole body moves upwards for a certain distance when vibrating, so that the extrusion barrel 6 is far away from the chenodeoxycholic acid, and the chenodeoxycholic acid attached to the lower surface of the extrusion barrel 6 can shake off when the extrusion barrel 6 vibrates, so that the shake-off chenodeoxycholic acid falls into the filter cylinder 3 again, and the passive cleaning function of the extrusion barrel 6 is realized.
Further, when the chenodeoxycholic acid in the filter cartridge 3 needs to be taken out, only the connecting rod 8 needs to be rotated to enable the extrusion cylinder 6 to be positioned at the cover plate 9, so that enough space is provided for taking out the chenodeoxycholic acid.
While certain exemplary embodiments of the present invention have been described above by way of illustration only, it will be apparent to those of ordinary skill in the art that modifications may be made to the described embodiments in various different ways without departing from the spirit and scope of the invention. Accordingly, the drawings and description are to be regarded as illustrative in nature and not as restrictive of the scope of the invention, which is defined by the appended claims.
Claims (5)
1. The full-automatic chenodeoxycholic acid production device comprises a shell and is characterized in that a bracket is connected in a sliding manner in the shell, a filter cartridge is connected to the bracket in a rotating manner, a driving mechanism for controlling the bracket to lift and the filter cartridge to centrifugally rotate is arranged in the shell, and a passive feeding mechanism is arranged above the filter cartridge;
the passive feeding mechanism comprises an extrusion barrel and a blocking rod for controlling the opening and closing of an outlet of the extrusion barrel, a raw material bin is arranged in the extrusion barrel, the extrusion barrel is arranged above the filter cartridge, and the blocking rod controls the opening and closing of the outlet of the extrusion barrel based on the distance between the extrusion barrel and the filter cartridge;
the bracket comprises a circular ring section and a sliding connection section which are connected;
a baffle plate is fixedly connected in the extrusion cylinder, and a drainage hole is formed in the plugging rod;
the baffle is in a ring shape, the outer ring of the baffle is fixedly connected with the inner wall of the extrusion cylinder, the inner ring of the baffle is sleeved on the vertical section of the plugging rod in a sliding way, the baffle divides a raw material bin in the extrusion cylinder into an upper cavity and a lower cavity, a plurality of drainage holes are formed in the circumferential array of the vertical section of the plugging rod, and two ends of each drainage hole are respectively positioned in the upper cavity and the lower cavity;
in the initial state, the blocking rod is at the lowest position under the action of mixed solution, self weight and a first spring, at the moment, the blocking disc blocks the outlet of the extrusion cylinder, mixed solution in the upper cavity can flow into the lower cavity through the drainage hole and completely fills the lower cavity, when the sliding connection section is contacted with the abutting section and extruded, the blocking rod is driven to move upwards, at the moment, the outlet at the bottom end of the drainage hole can enter the upper cavity from the lower cavity, the baffle is sealed and attached to the vertical section of the blocking rod, so that the upper cavity and the lower cavity cannot be communicated, mixed solution in the upper cavity cannot enter the lower cavity, meanwhile, the original mixed solution in the lower cavity can flow into the filter cylinder through the outlet, and the mixed solution in the upper cavity cannot flow into the lower cavity when flowing into the filter cylinder, so that the amount of the mixed solution flowing into the filter cylinder each time is fixed, and the quantitative addition of the mixed solution is realized;
the driving mechanism comprises a driving motor and a first driving wheel connected with the output end of the driving motor, the driving motor is fixedly connected to the inner bottom wall of the shell, a threaded rod is fixedly connected to the first driving wheel, and the threaded rod is in threaded connection with the bracket;
the driving mechanism further comprises a second driving wheel, the second driving wheel is rotationally connected with the inner bottom wall of the shell, the first driving wheel and the second driving wheel are driven by a belt, a sleeve is fixedly connected to the periphery of the filter cartridge, and a driving rod is fixedly connected between the sleeve and the second driving wheel;
the transmission rod comprises a first rod body and a second rod body, the first rod body is fixedly connected to the second transmission wheel, the second rod body is fixedly connected to the sleeve, and the first rod body is in sliding connection with the second rod body;
a limiting block is fixedly connected to the second rod body, and a limiting groove matched with the limiting block is formed in the first rod body;
the first rod body is fixedly connected to the upper surface of the second driving wheel, the second rod body is fixedly connected to the lower surface of the sleeve, the other ends of the first rod body and the second rod body are connected in a sliding mode, the limiting block is fixedly connected to the outer surface of the second rod body, and the length of the limiting block is smaller than the rising height of the filter cylinder.
2. The fully automatic chenodeoxycholic acid production device according to claim 1, wherein a sealing plate is fixedly connected to the plugging rod.
3. The fully automatic chenodeoxycholic acid production device according to claim 1, wherein a pressure sensor is arranged on the extrusion cylinder and is electrically connected with the driving mechanism.
4. The fully automatic chenodeoxycholic acid production device according to claim 1, wherein a plurality of through holes are circumferentially formed in the bottom end of the sleeve.
5. The fully automatic chenodeoxycholic acid production device according to claim 4, wherein a collecting tank is fixedly connected to the bracket, the collecting tank is located below the sleeve and surrounds the sleeve, and a guide plate is arranged in the collecting tank.
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| CN202211564275.9A CN115739408B (en) | 2022-12-07 | 2022-12-07 | Full-automatic chenodeoxycholic acid apparatus for producing |
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| CN202211564275.9A CN115739408B (en) | 2022-12-07 | 2022-12-07 | Full-automatic chenodeoxycholic acid apparatus for producing |
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| CN115739408B true CN115739408B (en) | 2024-03-29 |
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| CN115739408A (en) | 2023-03-07 |
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