CN115737748A - External application medicine for treating scrofula - Google Patents
External application medicine for treating scrofula Download PDFInfo
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- CN115737748A CN115737748A CN202211443758.3A CN202211443758A CN115737748A CN 115737748 A CN115737748 A CN 115737748A CN 202211443758 A CN202211443758 A CN 202211443758A CN 115737748 A CN115737748 A CN 115737748A
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Abstract
The invention provides a traditional Chinese medicine composition for treating scrofula and a preparation method thereof, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 18 to 30 parts of selfheal, 12 to 18 parts of rhizoma polygonati, 10 to 20 parts of cortex lycii radicis, 6 to 18 parts of great burdock achene, 8 to 15 parts of radix ranunculi ternati, 6 to 15 parts of white muscardine silkworm, 5 to 18 parts of pinellia ternate, 3 to 9 parts of kelp and 3 to 9 parts of sculellaria barbata. The various medicinal materials of the invention interact and supplement each other, have the effects of calming the liver, tonifying the spleen, dredging collaterals, resolving masses, reducing phlegm and detoxifying, can effectively prevent and treat scrofula, and has remarkable curative effect and no toxic or side effect.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for preventing and treating scrofula and a preparation method thereof.
Background
Lymphoid tuberculosis, called scrofula in traditional Chinese medicine, is a toxic mass tissue reflected on the surface of muscles and is formed by phlegm, toxicity, heat and toxic coagulation of liver and lung. Western medicine refers to the treatment of cancer in the human body by disinfection to protect the blood vessels and lymphatic system of tissues, and the cancer may be coagulated and colonized in the superficial tissues of the body by the virus which cannot be removed and killed in vivo or in vitro. The scrofula grows into lumps on one side or two sides of the neck, is not painful, does not itch, is pushed into the neck to slide, does not have obvious pressure pain, gradually increases if the body resistance is low, the skin becomes purple, and finally breaks the running watery pus and discharges yellow and turbid cheese-like pus, so the traditional Chinese medicine is called as 'mouse sore'. Repeated ulceration is less, and part of patients can have general poisoning symptoms such as low fever, night sweat, inappetence, emaciation and the like. If the scrofula is not healed for a long time, the disease condition is aggravated, a fistula is formed in the body, normal muscle tissues are damaged, the development of the scrofula on the neck can reach the head, repeated stimulation to the affected part can be caused to cause cancer, and the lymph gland of the human body can spread and finally die. At present, the western medicine treatment method mainly adopts local surgical excision or puncture pus-drawing treatment and combines western medicine treatment, but the surgical treatment is painful, so that patients suffer from the pain of diseases for a long time; the long-term use of antituberculosis drugs can cause the side effect of damaging the liver system, and the liver function and the whole immunity of the body are reduced.
The traditional Chinese medicine considers that the scrofula is mostly caused by the accumulation of wind-heat and qi-toxin in the triple energizer, liver, gallbladder and the like, and the liver and kidney are caused by the deficiency of qi and blood and the internal stirring of deficient fire, and can be divided into acute and chronic diseases, wherein the acute diseases are caused by the external wind-heat and the internal phlegm-toxin; chronic disease is usually caused by qi stagnation and deficiency, but the traditional Chinese medicine effect is not obvious at present. Therefore, intensive studies from the medical field are necessary to solve the problems yet to be solved.
Disclosure of Invention
The invention aims to provide an external application traditional Chinese medicine composition for preventing and treating scrofula, which can treat the scrofula in a short time, has an obvious curative effect, is safe and has no toxic or side effect.
In order to achieve the above object, the present invention provides the following technical solutions:
the invention provides a traditional Chinese medicine composition for preventing and treating scrofula, which comprises the following raw materials in parts by weight: 18 to 30 parts of selfheal, 12 to 18 parts of rhizoma polygonati, 10 to 20 parts of cortex lycii radicis, 6 to 18 parts of great burdock achene, 8 to 15 parts of radix ranunculi ternati, 6 to 15 parts of white muscardine silkworm, 5 to 18 parts of pinellia ternate, 3 to 9 parts of kelp and 3 to 9 parts of sculellaria barbata.
The invention provides a preparation method of the traditional Chinese medicine composition, which comprises the following steps: soaking the Chinese medicinal composition, oven drying, pulverizing, adding Mel and oleum Sesami, and decocting to obtain paste.
Preferably, the soaking time is 0.5-2 h.
Preferably, the drying temperature is 40-60 ℃, and the drying time is 0.5-1 h.
Preferably, the pulverized particle size is 30 to 45 μm.
Preferably, the volume ratio of the traditional Chinese medicine composition to the honey and the sesame oil is 1:5 to 8:50 to 80.
The invention provides an application of the traditional Chinese medicine composition in preparing a medicine for treating scrofula and complications thereof.
Preferably, the traditional Chinese medicine composition is added with pharmaceutically acceptable pharmaceutical adjuvants to be prepared into clinically acceptable tablets, powders, granules, capsules or oral liquids.
Compared with the prior art, the invention has the following technical effects:
the medicines of the invention are compatible and complement each other, and the main treatment principles of calming the liver and tonifying the spleen, dredging collaterals and dissipating stagnation, and reducing phlegm and detoxifying are taken to achieve the purpose of treating both principal and secondary aspects of diseases. In the formula, the selfheal, the rhizoma polygonati and the cortex lycii radicis are taken as monarch drugs, so that the effects of calming the liver, tonifying the spleen, dredging collaterals, eliminating stagnation and reducing swelling are achieved; fructus arctii and radix ranunculi ternati are used as ministerial drugs, and monarch drugs are used for reducing phlegm and resolving masses, reducing swelling and treating sore; the white muscardine silkworm and the kelp are adjuvant drugs and assist monarch drugs and ministerial drugs to strengthen the effects of reducing phlegm and resolving masses, and detoxifying and reducing swelling; the pinellia ternate and the sculellaria barbata are used as guiding drugs and are used for harmonizing the effects of activating blood circulation, removing blood stasis and dissipating stagnation in the recipe. The traditional Chinese medicine formula provided by the invention is scientific in compatibility, the honey and the sesame oil are added to be mixed and applied to the affected part, the effects of treating the scrofula are achieved through the medicines, the medicine safety is high, the curative effect is obvious, and the treatment course is short.
Detailed Description
The invention provides a traditional Chinese medicine composition for preventing and treating scrofula, which comprises the following raw materials in parts by weight: 18 to 30 parts of selfheal, 12 to 18 parts of rhizoma polygonati, 10 to 20 parts of cortex lycii radicis, 6 to 18 parts of great burdock achene, 8 to 15 parts of radix ranunculi ternati, 6 to 15 parts of white muscardine silkworm, 5 to 18 parts of pinellia ternate, 3 to 9 parts of kelp and 3 to 9 parts of sculellaria barbata. Preferably, the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 20 to 28 parts of selfheal, 13 to 16 parts of rhizoma polygonati, 12 to 18 parts of cortex lycii radicis, 8 to 15 parts of great burdock achene, 10 to 14 parts of radix ranunculi ternati, 8 to 12 parts of white muscardine silkworm, 8 to 15 parts of pinellia ternate, 5 to 8 parts of kelp and 5 to 8 parts of sculellaria barbata. More preferably, the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 22 to 25 portions of selfheal, 14 to 15 portions of rhizoma polygonati, 13 to 15 portions of cortex lycii radicis, 10 to 12 portions of great burdock achene, 12 to 13 portions of radix ranunculi ternati, 9 to 10 portions of white muscardine silkworm, 10 to 12 portions of pinellia ternate, 6 to 7 portions of kelp and 6 to 7 portions of sculellaria barbata.
The selfheal in the invention has pungent, bitter and cold properties; it enters liver and gallbladder meridians. It has effects in clearing liver-fire, improving eyesight, and eliminating stagnation; it is mainly used for conjunctival congestion, swelling and pain, bulbar nyctalgia, headache, giddiness, scrofula, goiter, mammary abscess, mammary nodules, and breast pain.
Rhizoma polygonati is sweet in nature and taste and mild in nature and taste; it enters spleen, lung and kidney meridians. Has the effects of invigorating qi, nourishing yin, invigorating spleen, moistening lung, and invigorating kidney; is mainly used for treating deficiency of spleen-stomach qi, tiredness, hypodynamia, stomach yin deficiency, dry mouth, poor appetite, lung deficiency, dry cough, hemoptysis, essence and blood deficiency, soreness and weakness of waist and knees, early white beard and hair, internal heat and thirst quenching.
Cortex Lycii, sweet in nature and flavor and cold in nature, enters lung and kidney meridians. Has effects of clearing away heat and toxic materials, cooling blood, removing heat from the blood, clearing lung-heat, and lowering fire, and is suitable for treating fever due to yin deficiency, hectic fever due to yin deficiency, night sweat, dry throat, dry mouth, red tongue with little coating, hemorrhage due to blood heat, cough due to lung heat, etc.
Burdock, pungent, bitter and cold in nature; it enters lung and stomach meridians. Has the effects of dispelling wind and heat, ventilating lung, relieving sore throat, removing toxic substance, promoting eruption, relieving swelling and treating sore. It is mainly used for wind-heat type common cold, early stage of epidemic febrile disease, measles without adequate eruption, carbuncle, swelling and sore.
Cat scrabble herb is sweet and pungent in nature and flavor and warm in nature. It enters liver and lung meridians. Has the effects of reducing phlegm and resolving masses, and detoxifying and reducing swelling. It is mainly used for scrofula, subcutaneous nodule, furuncle, toxic swelling, snake and insect bite.
Bai Jiang Can, salty in property and mild in flavor. Enters liver, lung and stomach meridians. Has the effects of dispelling wind, relieving spasm, eliminating phlegm and resolving masses. It can be used for treating apoplexy, epilepsy, headache, and laryngopathy. Laryngeal obstruction, scrofula and tuberculosis. Urticaria, erysipelas, mastitis.
Ban Xia is pungent in flavor and warm in nature. It enters spleen, stomach and lung meridians. Has the effects of eliminating dampness and phlegm, lowering adverse qi and preventing vomiting, and relieving distension and fullness and dissipating mass. Mainly used for treating damp phlegm and cold phlegm, cough, asthma, excessive phlegm, phlegm retention, dizziness, palpitation, wind phlegm, dizziness, phlegm syncope, headache, vomiting, regurgitation, feeling of fullness in the chest and epigastrium, globus hystericus; it is indicated for abscess with phlegm nodule.
Kun Bu is salty in flavor and cold in nature. It enters liver, stomach and kidney meridians. Has the effects of eliminating phlegm, softening hardness, dissipating stagnation, inducing diuresis and relieving swelling. It is mainly used for goiter, scrofula, swollen and painful testis, phlegm-fluid retention and edema.
Scutellaria barbata is pungent, bitter and cold in nature. It enters lung, liver and kidney meridians. Has the effects of clearing away heat and toxic materials, removing blood stasis, and promoting urination. It is mainly used for treating furuncle, swelling and pain of throat, traumatic injury, edema, jaundice, snake and insect bite.
The medicines of the invention are compatible and complement each other, and the main treatment principles of calming the liver and tonifying the spleen, dredging collaterals and dissipating stagnation, and reducing phlegm and detoxifying are taken to achieve the purpose of treating both principal and secondary aspects of diseases. In the formula, selfheal, rhizoma polygonati and cortex lycii radicis are used as monarch drugs, so that the effects of calming the liver, tonifying the spleen, dredging collaterals, dissipating stagnation and diminishing swelling are achieved; fructus arctii and radix ranunculi ternati are used as ministerial drugs, and monarch drugs are used for reducing phlegm and resolving masses, reducing swelling and treating sore; the white muscardine silkworm and the kelp are adjuvant drugs and assist monarch drugs and ministerial drugs to strengthen the effects of reducing phlegm and resolving masses, and detoxifying and reducing swelling; the pinellia ternate and the sculellaria barbata are used as guiding drugs and are used for harmonizing the effects of activating blood circulation, removing blood stasis and dissipating stagnation in the recipe. The traditional Chinese medicine formula provided by the invention is scientific in compatibility, the honey and the sesame oil are added to be mixed and applied to the affected part, the effects of treating the scrofula are achieved through the medicines, the medicine safety is high, the curative effect is obvious, and the treatment course is short.
The invention provides a preparation method of the traditional Chinese medicine composition, which comprises the following steps: soaking the Chinese medicinal composition, oven drying, pulverizing, adding Mel and oleum Sesami, and decocting to obtain paste. In the invention, sesame oil is added as a medicine carrier, and the effects of softening and protecting skin are achieved at the same time; the honey is added to improve the state of the traditional Chinese medicine composition, and the traditional Chinese medicine composition also has the effects of tonifying middle-jiao, moistening dryness and detoxifying, and improves the efficacy of each traditional Chinese medicine.
In the invention, the soaking time is 0.5-2 h. Preferably, the soaking time is 1 to 1.5 hours. The traditional Chinese medicine raw material is fully soaked, so that impurities on the surface of the traditional Chinese medicine raw material can be effectively removed, and the dissolution of each effective component in the using process can be further realized.
In the invention, the drying temperature is 40-60 ℃, and the drying time is 0.5-1 h. Preferably, the drying temperature is 45-55 ℃, and the drying time is 0.6-0.8 h. The invention optimizes the drying temperature and time, so that the medicinal components of the traditional Chinese medicine are more completely retained, and the subsequent crushing process is facilitated.
In the present invention, the pulverized particle size is 30 to 45 μm. Preferably, the particle size is 35 to 40 μm. The invention crushes the traditional Chinese medicine composition into particles, is beneficial to dissolving out effective components and better exerts the drug effect.
In the invention, the volume ratio of the traditional Chinese medicine composition to honey and sesame oil is 1:5 to 8:50 to 80. Preferably, the volume ratio is 1:6 to 7:60 to 70. In the invention, the traditional Chinese medicine composition is a pulverized traditional Chinese medicine composition. In the invention, sesame oil is added as a medicine carrier, and the effects of softening and protecting skin are achieved at the same time; the honey is added to improve the state of the traditional Chinese medicine composition, and the traditional Chinese medicine composition also has the effects of tonifying middle-jiao, moistening dryness and detoxifying, and improves the efficacy of each traditional Chinese medicine.
The invention provides application of the traditional Chinese medicine composition in preparing a medicine for treating scrofula and complications thereof.
In the invention, the traditional Chinese medicine composition is added with pharmaceutically acceptable pharmaceutical adjuvants to be prepared into clinically acceptable tablets, powder, granules, capsules or oral liquid.
The technical solution of the present invention will be clearly and completely described below with reference to the embodiments of the present invention. It is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
The traditional Chinese medicine composition for preventing and treating scrofula is characterized by comprising the following raw materials in parts by weight: 25 parts of selfheal, 15 parts of rhizoma polygonati, 18 parts of cortex lycii radicis, 10 parts of burdock, 10 parts of radix ranunculi ternati, 8 parts of white muscardine silkworm, 12 parts of pinellia ternate, 6 parts of kelp and 8 parts of sculellaria barbata.
Example 2
The traditional Chinese medicine composition for preventing and treating scrofula is characterized by comprising the following raw materials in parts by weight: 18 parts of selfheal, 12 parts of rhizoma polygonati, 10 parts of cortex lycii radicis, 6 parts of burdock, 8 parts of radix ranunculi ternati, 6 parts of white muscardine silkworm, 5 parts of pinellia ternate, 3 parts of kelp and 3 parts of sculellaria barbata.
Example 3
The traditional Chinese medicine composition for preventing and treating scrofula is characterized by comprising the following raw materials in parts by weight: 30 parts of selfheal, 18 parts of rhizoma polygonati, 20 parts of cortex lycii radicis, 18 parts of burdock, 18 parts of radix ranunculi ternati, 15 parts of white muscardine silkworm, 18 parts of pinellia ternate, 9 parts of kelp and 9 parts of sculellaria barbata.
Example 4
A preparation method of a traditional Chinese medicine composition for preventing and treating scrofula comprises the following steps: soaking the traditional Chinese medicine composition in the embodiment 1 for 1h, drying at 55 ℃ for 1h, and then crushing to 35 microns, wherein the volume ratio of the traditional Chinese medicine composition to honey and sesame oil is 1:6:65 adding Mel and oleum Sesami, and decocting to obtain paste.
Example 5
Different from the embodiment 4, the components are weighed according to the raw material proportion described in the embodiment 2, and the rest steps are unchanged.
Example 6
Different from the embodiment 4, the components are weighed according to the raw material proportion described in the embodiment 3, and the rest steps are unchanged.
Example 7
Different from the example 4, the soaking time is 0.5h, and the rest steps are unchanged.
Example 8
Unlike example 4, the soaking time was 2h, and the remaining steps were unchanged.
Example 9
Different from the embodiment 4, the drying temperature is 40 ℃, the drying time is 0.8h, and the rest steps are unchanged.
Example 10
Different from the embodiment 4, the drying temperature is 60 ℃, the drying time is 0.5h, and the rest steps are unchanged.
Example 11
In contrast to example 4, the comminution to 30 μm was carried out without further modification.
Example 12
In contrast to example 4, the comminution to 45 μm was carried out without further modification.
Example 13
Different from the embodiment 4, the volume ratio of the traditional Chinese medicine composition to the honey and the sesame oil is 1:5:50 adding Mel and oleum Sesami, and keeping the rest steps unchanged.
Example 14
Different from the embodiment 4, the volume ratio of the traditional Chinese medicine composition to the honey and the sesame oil is 1:8:80 adding Mel and oleum Sesami, and keeping the rest steps unchanged.
Example 15 application of the Chinese medicinal composition of the invention in preventing and treating lymphoid tuberculosis
The basis of diagnosis is as follows: according to the regulation of Chinese medicine syndrome diagnosis curative effect standard (ZY/T001.1-94), which is a Chinese medicine industry standard of the people's republic of China, reference is made to the diagnosis basis of scrofula, namely, single or multiple nuclear-shaped masses are arranged on one side or two sides of the neck at the beginning, and the masses can be removed, so that the skin color is unchanged and the pain is avoided; the disease condition develops, the nucleus lumps adhere to the skin, and mild pain occurs. When suppuration occurs, the skin turns into dark red, the mass turns soft, and the pus is thin after the abscess is broken, and the pus is filled with the septicemia sample. The deep-rooted sores may form sinus passages if they are not healed for a long time. There may be a history of tuberculosis or a history of exposure to tuberculosis. The tuberculin test is strong positive, and the blood sedimentation rate is increased. Pathological activity can aid diagnosis.
160 outpatients are selected, and all patients meet the diagnosis basis of scrofula. 160 patients were randomly divided into-140 patients in the treatment group, 240 patients in the treatment group, 340 patients in the treatment group and 40 patients in the control group; the comparative differences of age, sex, disease course, clinical manifestations and disease severity of the four groups have no statistical significance (p > 0.05).
The treatment method comprises the following steps:
treatment group-1: an appropriate amount of the ointment prepared in the embodiment 4 is applied to an affected part, gauze is fixed, and the ointment is applied once in the morning and at night, wherein 15 days is a treatment course.
Treatment group-2: an appropriate amount of the ointment prepared in the embodiment 5 is applied to an affected part, gauze is fixed, and the ointment is applied once in the morning and at night, wherein 15 days is a treatment course.
Treatment group-3: an appropriate amount of the ointment prepared in the embodiment 6 is applied to an affected part, gauze is fixed, and the ointment is applied once in the morning and at night, wherein 15 days is a treatment course.
Control group: the selfheal paste is taken according to the prescription.
The treatment effect judgment standard is as follows:
and (3) curing: the lump dissipates or the sinus heals, and the general symptoms disappear;
improvement: the lump is reduced or the pus in the sinus is reduced, and the general symptoms are improved;
the disease is not cured: the lump is not eliminated, the sinus is not healed, and the general symptoms are not improved.
TABLE 1 four groups of the composition have clinical effects after two courses of treatment
| Cure of disease | Is effective | Invalidation | High efficiency | |
| Treatment group-1 | 18 | 20 | 2 | 95％ |
| Treatment group-2 | 15 | 21 | 4 | 90％ |
| Treatment group-3 | 16 | 19 | 5 | 87.5％ |
| Control group | 10 | 18 | 12 | 70％ |
By performing clinical drug tests on the traditional Chinese medicine composition of the invention, it can be seen from table 1 that: the traditional Chinese medicine composition of the embodiment 4-6 can effectively treat scrofula, and the effective rate is up to more than 85%.
Typical cases are:
li Mou, age 32, with many nucleid masses on the left side of the neck, it is not painful and itchy, and is diagnosed as lymphoid tuberculosis. After the ointment of the embodiment 4 of the invention is applied for two courses of treatment, tuberculosis disappears, and corresponding diseases disappear; the application is continued for a course of treatment, and the follow-up is not recurrent until now.
Yang Mou, age 44, with a lump in the right neck, the movement of tui was diagnosed as lymphoid tuberculosis. After two courses of treatment with the ointment of example 4 of the present invention, the mass subsided. After two treatment courses, no lump appeared.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, various modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.
Claims (8)
1. The traditional Chinese medicine composition for preventing and treating scrofula is characterized by comprising the following raw materials in parts by weight: 18 to 30 parts of selfheal, 12 to 18 parts of rhizoma polygonati, 10 to 20 parts of cortex lycii radicis, 6 to 18 parts of great burdock achene, 8 to 15 parts of ternate buttercup root, 6 to 15 parts of white muscardine silkworm, 5 to 18 parts of pinellia tuber, 3 to 9 parts of kelp and 3 to 9 parts of barbed skullcap herb.
2. The preparation method of the traditional Chinese medicine composition of claim 1, which is characterized by comprising the following steps: soaking the Chinese medicinal composition, oven drying, pulverizing, adding Mel and oleum Sesami, and decocting to obtain paste.
3. The method according to claim 2, wherein the soaking time is 0.5 to 2 hours.
4. The preparation method according to claim 2, wherein the drying temperature is 40-60 ℃ and the drying time is 0.5-1 h.
5. The method according to claim 2, wherein the pulverized particle size is 30 to 45 μm.
6. The preparation method of claim 2, wherein the volume ratio of the traditional Chinese medicine composition to the honey and the sesame oil is 1:5 to 8:50 to 80.
7. The use of the composition of claim 1 in the preparation of a medicament for the treatment of lymphoid tuberculosis and its complications.
8. The use of claim 7, wherein the composition is formulated with pharmaceutically acceptable pharmaceutical adjuvants into clinically acceptable tablets, powders, granules, capsules or oral liquids.
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| CN104324143A (en) * | 2014-10-23 | 2015-02-04 | 宋群库 | Traditional Chinese medicine composition for treating scrofula |
| CN106109917A (en) * | 2016-08-05 | 2016-11-16 | 牟清海 | A kind of external treatment solution treating thyroid tumor |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104324143A (en) * | 2014-10-23 | 2015-02-04 | 宋群库 | Traditional Chinese medicine composition for treating scrofula |
| CN106109917A (en) * | 2016-08-05 | 2016-11-16 | 牟清海 | A kind of external treatment solution treating thyroid tumor |
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