CN115708530B - Pregnant and lying-in woman formula milk powder capable of promoting digestion comfort and stabilizing blood sugar and preparation method thereof - Google Patents

Pregnant and lying-in woman formula milk powder capable of promoting digestion comfort and stabilizing blood sugar and preparation method thereof Download PDF

Info

Publication number
CN115708530B
CN115708530B CN202211429648.1A CN202211429648A CN115708530B CN 115708530 B CN115708530 B CN 115708530B CN 202211429648 A CN202211429648 A CN 202211429648A CN 115708530 B CN115708530 B CN 115708530B
Authority
CN
China
Prior art keywords
powder
milk
parts
pregnant
lying
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202211429648.1A
Other languages
Chinese (zh)
Other versions
CN115708530A (en
Inventor
粘靖祺
孙健
王帅
宫春颖
高鹏
车佳玲
赵臻
王青云
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beidahuang Wandashan Dairy Co ltd
Original Assignee
Beidahuang Wandashan Dairy Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beidahuang Wandashan Dairy Co ltd filed Critical Beidahuang Wandashan Dairy Co ltd
Priority to CN202211429648.1A priority Critical patent/CN115708530B/en
Publication of CN115708530A publication Critical patent/CN115708530A/en
Application granted granted Critical
Publication of CN115708530B publication Critical patent/CN115708530B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87Re-use of by-products of food processing for fodder production

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to pregnant and lying-in women formula milk powder for promoting digestion comfort and stabilizing blood sugar and a preparation method thereof, and belongs to the technical field of milk powder processing. In order to solve the problem that the prior pregnant and lying-in woman milk powder has incomplete consideration on nutrient absorbability and product comfortableness, the invention provides the pregnant and lying-in woman formula milk powder for promoting digestion comfortableness and stabilizing blood sugar, which comprises the components of A2 type skim milk, lactose, whey protein powder, cream, galacto-oligosaccharide, fructo-oligosaccharide, phospholipid, compound nutrition enhancer, docosahexaenoic acid grease powder, N-acetylneuraminic acid and compound probiotic powder. The nutrient such as A2β -casein, organic minerals, active folic acid and the like in the formula milk powder for pregnant and lying-in women provided by the invention has the characteristics of strong absorbability and the like, can assist the pregnant and lying-in women to reasonably absorb the required nutrient substances, and is particularly suitable for being eaten by pregnant women, pregnant women and postpartum women suffering from gestational diabetes mellitus, and having weak intestinal functions and high requirements on digestion and absorption of the nutrient substances.

Description

Pregnant and lying-in woman formula milk powder capable of promoting digestion comfort and stabilizing blood sugar and preparation method thereof
Technical Field
The invention belongs to the technical field of milk powder processing, and particularly relates to pregnant and lying-in woman formula milk powder capable of promoting digestion comfort and stabilizing blood sugar and a preparation method thereof.
Background
The nutrition supplement in pregnancy and lactation is directly related to the health of the mother and child.
Although the pregnant and lying-in women milk powder products on the market at present consider the enhanced nutrients, the problems of incomplete consideration of the absorbability of the nutrients and the comfort of the products still exist due to weak intestinal functions and poor digestion and absorption capacity of pregnant women; inorganic mineral salts and synthetic folic acid products are most available in the market, organic mineral salts and natural folic acid products are less, and targeted reinforcement of intake and absorbability is not considered; although some products are marked without sugar, other raw materials and auxiliary materials in the formula can also influence the blood sugar during pregnancy, and the pregnant and lying-in women with stable blood sugar is purposefully considered to have fewer products, so that the pregnant and lying-in women formula milk powder with good nutrient absorption and product comfort is urgently needed to be developed.
Disclosure of Invention
The invention provides pregnant and lying-in woman formula milk powder capable of promoting digestion comfort and stabilizing blood sugar and a preparation method thereof, and aims to solve the problem that the existing pregnant and lying-in woman milk powder is not comprehensive in consideration of nutrient absorbability and product comfort.
The technical scheme of the invention is as follows:
The pregnant and lying-in woman formula milk powder for promoting digestion comfort and stabilizing blood sugar comprises the following raw material components in parts by weight: 50 to 85 parts of A2 type defatted raw milk, 0 to 30 parts of lactose, 0 to 4 parts of whey protein powder, 0 to 25 parts of cream, 1 to 6 parts of galacto-oligosaccharide, 1 to 6 parts of fructo-oligosaccharide, 0.2 to 0.6 part of phospholipid, 0.6 to 1.0 part of compound nutrition enhancer, 0.5 to 1.5 parts of docosahexaenoic acid grease powder, 0.03 to 0.2 part of N-acetylneuraminic acid and 0.04 to 0.08 part of compound probiotics powder.
Further, the material comprises the following raw material components in parts by weight: 60 to 80 parts of A2 type defatted raw milk, 0 to 25 parts of lactose, 0 to 2.5 parts of whey protein powder, 0 to 20 parts of cream, 2 to 3.5 parts of galacto-oligosaccharide, 2 to 5.5 parts of fructo-oligosaccharide, 0.2 to 0.5 part of phospholipid, 0.6 to 0.9 part of compound nutrition enhancer, 0.8 to 1.5 parts of docosahexaenoic acid oil fat powder, 0.05 to 0.18 part of N-acetylneuraminic acid and 0.05 to 0.06 part of compound probiotics powder.
Further, the material comprises the following raw material components in parts by weight: 65 to 80 parts of A2 type defatted raw milk, 0 to 20 parts of lactose, 0 to 2 parts of whey protein powder, 0 to 18 parts of cream, 2.5 to 3.5 parts of galacto-oligosaccharide, 3 to 5.5 parts of fructo-oligosaccharide, 0.3 to 0.5 part of phospholipid, 0.7 to 0.9 part of compound nutrition enhancer, 0.8 to 1.2 parts of docosahexaenoic acid oil fat powder, 0.05 to 0.18 part of N-acetylneuraminic acid and 0.05 to 0.06 part of compound probiotics powder.
Further, the compound nutrition enhancer comprises the following components in parts by weight: 60-80 parts of compound vitamins, 20-40 parts of compound minerals and 1-5 parts of lactose.
Further, the compound vitamin comprises the following components in percentage by weight: 0.55 to 0.85 percent of vitamin A, 0.4 to 0.5 percent of vitamin D, 3.5 to 4.8 percent of vitamin E, 3.00 to 4.00 percent of vitamin K 2, 0.10 to 0.15 percent of vitamin B 1, 1.00 to 1.50 percent of vitamin B 2, 3.00 to 3.80 percent of vitamin B 6, 0.05 to 0.15 percent of 6S-5-methyltetrahydrofolate calcium, 0.02 to 0.08 percent of vitamin B 12, 19.00 to 22.00 percent of vitamin C, 20.10 to 28.50 percent of choline, 4.00 to 5.50 percent of L-carnitine, 4.20 to 5.50 percent of taurine and the balance of lactose.
Further, the compound mineral comprises the following components in percentage by weight: 15.00 to 25.00 percent of ferrous gluconate, 6.50 to 8.70 percent of zinc gluconate, 0.75 to 1.25 percent of sodium selenite and the balance of lactose.
Further, the composite probiotic powder is composed of at least two of bifidobacterium animalis subspecies Bb-12, bifidobacterium animalis subspecies HN019, bifidobacterium animalis subspecies Bi-07 and bifidobacterium longum subspecies BB536 according to any proportion.
A preparation method of pregnant and lying-in woman formula milk powder for promoting digestion comfort and stabilizing blood sugar comprises the following steps:
step one, screening and collecting A2 raw cow milk:
selecting pure breed A2 dairy cows and carrying out clustered breeding and cultivation and collecting A2 raw dairy cows by carrying out gene identification screening on large-scale pasture dairy cows;
Step two, degreasing the raw milk of the A2:
filtering, cooling and storing the A2 raw milk obtained in the step one, degreasing to obtain skimmed milk, homogenizing the skimmed milk after degerming and separating, and then pasteurizing to obtain pasteurized milk, and cooling and storing;
Step three, batching:
Adding other auxiliary materials except the docosahexaenoic acid grease powder, the N-acetylneuraminic acid, the compound nutrition enhancer and the compound probiotic powder into a vacuum mixer according to the formula weight parts to be mixed; dissolving the compound nutrition enhancer according to the water-powder mass ratio required by the process at the dissolving temperature, adding the dissolved compound nutrition enhancer into a vacuum mixer, and mixing the dissolved compound nutrition enhancer with other auxiliary materials and pasteurized milk obtained in the step two to obtain the prepared milk;
step four, preparing a semi-finished product of milk powder:
homogenizing the prepared milk obtained in the step three, removing most of water in the prepared milk through vacuum sterilization and concentration to obtain concentrated milk, and performing spray drying and fluidized bed cooling on the obtained concentrated milk to obtain a milk powder semi-finished product;
Step five, preparing a milk powder finished product:
premixing the docosahexaenoic acid grease powder, the N-acetylneuraminic acid and the compound probiotic powder with part of the semi-finished milk powder obtained in the step four according to the formula requirement in parts by weight to obtain a premix, fully mixing the rest semi-finished milk powder with the premix, and packaging to obtain the finished pregnant and lying-in woman formula milk powder.
Further, the impurity degree of the A2 raw milk obtained by filtering in the second step is less than 0.25ppm; step two, the pasteurization temperature is 80-85 ℃ and the sterilization time is 15s; in the third step, the mass ratio of water to powder is not lower than 8:1 when the compound nutrition enhancer is dissolved, and the dissolution temperature is 30-50 ℃.
Further, the homogenizing pressure in the fourth step is 160-210 bar, the sterilizing temperature of vacuum sterilization and concentration is 85-98 ℃, the moisture of the prepared milk removed by concentration is 60%, and the density of the obtained concentrated milk is 1100-1200 kg/m 3; the high-pressure pump pressure of the spray drying is 150-250 bar, the air inlet temperature is 160-200 ℃, the air exhaust temperature is 65-90 ℃, and the fluidized bed cooling is to cool the finished milk powder to 10-30 ℃; and fifthly, premixing for 5-10 min, wherein the mixing time is 5-10 min, the oxygen content in the package of the packaged bagged product is lower than 2.5%, and the oxygen content in the package of the canned product is lower than 5.0%.
The invention has the beneficial effects that:
The formula milk powder for pregnant and lying-in women provided by the invention has the effects of improving digestion and absorption functions of the pregnant and lying-in women and improving gastrointestinal comfort of the product. Aiming at the physiological characteristics of gastrointestinal tract digestion characteristics of pregnant and lying-in women, the raw material is preferably pure A2 beta-casein organic raw cow milk, and the raw material and whey protein (containing alpha-lactalbumin) are subjected to double-protein combination, so that the problem of weak gastrointestinal tract function of pregnant and lying-in women is improved on the basis of meeting the nutrient requirements of the pregnant and lying-in women, and the subsequent nutrient absorption is facilitated.
The formula milk powder for pregnant and lying-in women provided by the invention has the effect of enhancing nutrient absorption. The invention preferably adds the active folic acid, the organic mineral salt and the vitamin K 2, the active folic acid has better absorptivity, no metabolic step is needed, the addition is reasonable, and the kidney burden is small; the mineral sources preferably adopt organic mineral salts zinc gluconate and ferrous gluconate as ferric sulfate and zinc sulfate, so that the absorption effect is better; vitamin D and vitamin K 2 act synergistically to maintain bone health.
The formula milk powder for pregnant and lying-in women provided by the invention has the effect of stabilizing the blood sugar level of the pregnant and lying-in women. According to the invention, oligosaccharide and the like are added, white granulated sugar and the like are not added, the GI value is controlled to be less than or equal to 55, the GL value is less than 10, the food with low GI and low GL is provided, and meanwhile, the vitamin K 2 which is an important nutrition factor for controlling and preventing diabetes is added, so that the blood sugar level of pregnant and lying-in women can be stabilized.
The nutrient such as A2β -casein, organic minerals, active folic acid and the like in the formula milk powder for pregnant and lying-in women provided by the invention has the characteristics of strong absorbability and the like, can assist the pregnant and lying-in women to reasonably absorb the required nutrient substances, and is particularly suitable for being eaten by pregnant women, pregnant women and postpartum women suffering from gestational diabetes mellitus, and having weak intestinal functions and high requirements on digestion and absorption of the nutrient substances.
Drawings
Fig. 1 is a graph of the test blood glucose response of the food test for 12 subjects in example 4.
Detailed Description
The following embodiments are used for further illustrating the technical scheme of the present invention, but not limited thereto, and all modifications and equivalents of the technical scheme of the present invention are included in the scope of the present invention without departing from the spirit and scope of the technical scheme of the present invention. The process equipment or apparatus not specifically noted in the following examples are all conventional equipment or apparatus in the art, and the raw materials and the like used in the examples of the present invention are commercially available unless otherwise specified; unless specifically indicated, the technical means used in the embodiments of the present invention are conventional means well known to those skilled in the art.
Example 1
The embodiment provides pregnant and lying-in woman formula milk powder capable of promoting digestion comfort and stabilizing blood sugar and a preparation method thereof.
The pregnant and lying-in woman formula milk powder for promoting digestion comfort and stabilizing blood sugar provided by the embodiment comprises the following raw material components in parts by weight:
79 parts of A2 type skim raw milk based on dry matter,
18 Parts of cream,
3.4 Parts of galacto-oligosaccharide,
5.4 Parts of fructo-oligosaccharide,
0.3 Part of phospholipid,
0.8 Part of compound nutrition enhancer,
0.9 Part of docosahexaenoic acid grease powder,
0.053 Part of N-acetylneuraminic acid,
0.05 Part of composite probiotic powder.
The compound nutrition enhancer of the embodiment comprises the following components in percentage by weight: vitamin A0.75%, vitamin D0.47%, vitamin E4.2%, vitamin K 2 3.64.64%, vitamin B 1 0.15.15%, vitamin B 2 1.35.35%, vitamin B 6 3.29.29%, 6S-5-methyltetrahydrofolate calcium 0.1%, vitamin B 12 0.04.04%, ferrous gluconate 18.75%, zinc gluconate 7.66%, sodium selenite 0.95%, vitamin C19.61%, choline 24.51%, L-carnitine 4.90%, taurine 4.90% and lactose in balance.
The composite probiotic powder of the embodiment consists of bifidobacterium animalis subspecies Bb-12, bifidobacterium animalis subspecies HN019 and the ratio of 5:1.
The preparation method of the pregnant and lying-in woman formula milk powder for promoting digestion comfort and stabilizing blood sugar provided by the embodiment comprises the following steps:
step one, screening and collecting A2 raw cow milk:
the method comprises the steps of screening large-scale pasture cows by gene identification, selecting pure A2 cows, carrying out clustered breeding and cultivation on the cows producing A2 type beta-casein, and collecting A2 raw milk; the content of the A2 type beta-casein in the raw milk is 0.9-2.5 percent, and each index and the inspection method are executed according to GB 193012010 national Standard raw milk for food safety;
Step two, degreasing the raw milk of the A2:
Filtering the A2 raw milk obtained in the step one, wherein the impurity degree of the obtained A2 raw milk is less than 0.25ppm, cooling and storing, degreasing by a degreasing separator to obtain the skimmed milk, homogenizing the obtained skimmed milk after degerming and separating, performing pasteurization at 82 ℃ for 15s to ensure that bacteria of the skimmed milk reach a specified range, obtaining pasteurized milk, and cooling and storing;
Step three, batching:
Adding the cream, the galacto-oligosaccharide and the fructo-oligosaccharide which meet the standard and the phospholipid into a vacuum mixer according to the weight parts required by the formula to be mixed; dissolving the compound nutrition enhancer in a special nutrient tank according to the water-powder mass ratio of 9:1 required by the process at the temperature of 40 ℃, adding the dissolved compound nutrition enhancer into a vacuum mixer, and mixing the dissolved compound nutrition enhancer with other auxiliary materials and pasteurized milk obtained in the step two to obtain the prepared milk;
step four, preparing a semi-finished product of milk powder:
homogenizing the prepared milk obtained in the step three, wherein the homogenizing pressure is 180bar, then removing 60% of water in the prepared milk through vacuum sterilization and concentration at 90 ℃ to obtain concentrated milk with the density of 1100kg/m 3, spray-drying the obtained concentrated milk, wherein the pressure of a high-pressure pump for spray-drying is 200bar, the air inlet temperature is 180 ℃, the air outlet temperature is 85 ℃, and then cooling the finished milk powder to 20 ℃ by fluidized bed cooling to obtain a semi-finished milk powder;
Step five, preparing a milk powder finished product:
Premixing docosahexaenoic acid grease powder, N-acetylneuraminic acid and compound probiotics powder with part of the semi-finished milk powder obtained in the fourth step for 10min according to the formula requirement weight part to obtain premix, fully mixing the rest semi-finished milk powder with the premix for 10min, and packaging to obtain the finished milk powder for pregnant and lying-in women. The oxygen content in the package of the packaged bagged product is lower than 2.5%, and the oxygen content in the package of the canned product is lower than 5.0%.
The key technical indexes obtained by the pregnant and lying-in women formula milk powder prepared in the embodiment are shown in table 1.
TABLE 1
Example 2
The embodiment provides pregnant and lying-in woman formula milk powder capable of promoting digestion comfort and stabilizing blood sugar and a preparation method thereof.
The pregnant and lying-in woman formula milk powder for promoting digestion comfort and stabilizing blood sugar provided by the embodiment comprises the following raw material components in parts by weight:
73 parts of A2 type skim raw milk calculated by dry matter,
15 Parts of lactose,
Whey protein powder 1 part,
3.4 Parts of galacto-oligosaccharide,
5.4 Parts of fructo-oligosaccharide,
0.3 Part of phospholipid,
0.8 Part of compound nutrition enhancer,
1.2 Parts of docosahexaenoic acid grease powder,
0.154 Part of N-acetylneuraminic acid,
0.05 Part of composite probiotic powder.
The compound nutrition enhancer of the embodiment comprises the following components in percentage by weight: vitamin A0.75%, vitamin D0.47%, vitamin E4.2%, vitamin K 2 3.64.64%, vitamin B 1 0.15.15%, vitamin B 2 1.35.35%, vitamin B 6 3.29.29%, 6S-5-methyltetrahydrofolate calcium 0.1%, vitamin B 12 0.04.04%, ferrous gluconate 18.75%, zinc gluconate 7.00%, sodium selenite 0.95%, vitamin C19.61%, choline 24.51%, L-carnitine 4.90%, taurine 4.90% and lactose in balance.
The composite probiotic powder of the embodiment consists of bifidobacterium animalis subspecies Bb-12 and bifidobacterium longum subspecies BB536 according to the ratio of 4:1.
The content of the A2 type beta-casein in the raw milk is 0.9 to 2.5 percent; the alpha-lactalbumin in the milk base is added in the form of whey protein powder, and the content of the alpha-lactalbumin in the whey protein powder is 30-70%.
The preparation method of the pregnant and lying-in women formula milk powder of the embodiment is the same as that of the embodiment 1, and the technical indexes obtained by the prepared pregnant and lying-in women formula milk powder are shown in table 2.
TABLE 2
Nutrient project Content (per 100 g milk powder)
A2 type beta-casein 8.4g
Lactalbumin 1.2g
Folic acid 500μg
Vitamin K 2 35μg
Iron (Fe) 15mg
Zinc alloy 5mg
Probiotics 1.5×109CFU
N-acetylneuraminic acid 150mg
Dietary fiber 6.2g
Example 3
The embodiment provides pregnant and lying-in woman formula milk powder capable of promoting digestion comfort and stabilizing blood sugar and a preparation method thereof.
The pregnant and lying-in woman formula milk powder for promoting digestion comfort and stabilizing blood sugar provided by the embodiment comprises the following raw material components in parts by weight:
67 parts of A2 type defatted raw milk based on dry matter,
20 Parts of lactose,
Whey protein powder 2 parts,
3.4 Parts of galacto-oligosaccharide,
5.4 Parts of fructo-oligosaccharide,
0.3 Part of phospholipid,
0.8 Part of compound nutrition enhancer,
1 Part of docosahexaenoic acid grease powder,
0.12 Part of N-acetylneuraminic acid,
0.05 Part of composite probiotic powder.
The compound nutrition enhancer of the embodiment comprises the following components in percentage by weight: vitamin A0.75%, vitamin D0.47%, vitamin E4.2%, vitamin K 2 3.64.64%, vitamin B 1 0.15.15%, vitamin B 2 1.35.35%, vitamin B 6 3.29.29%, 6S-5-methyltetrahydrofolate calcium 0.13%, vitamin B 12 0.04.04%, ferrous gluconate 22.4%, zinc gluconate 7.00%, sodium selenite 0.95%, vitamin C19.61%, choline 24.51%, L-carnitine 4.90%, taurine 4.90% and lactose in balance.
The composite probiotic powder of the embodiment consists of bifidobacterium animalis subspecies Bb-12, bifidobacterium animalis subspecies HN019, bifidobacterium animalis subspecies Bi-07 and bifidobacterium longum subspecies BB536 according to equal proportion.
The content of the A2 type beta-casein in the raw milk is 0.9 to 2.5 percent; the alpha-lactalbumin in the milk base is added in the form of whey protein powder, and the content of the alpha-lactalbumin in the whey protein powder is 30-70%.
The preparation method of the pregnant and lying-in women formula milk powder of the embodiment is the same as that of the embodiment 1, and the technical indexes obtained by the prepared pregnant and lying-in women formula milk powder are shown in table 3.
TABLE 3 Table 3
Nutrient project Content (per 100 g milk powder)
A2 type beta-casein 8.0g
Lactalbumin 1.5g
Folic acid 400μg
Vitamin K 2 35μg
Iron (Fe) 18mg
Zinc alloy 5mg
Probiotics 1.5×109CFU
N-acetylneuraminic acid 100mg
Dietary fiber 6.2g
Example 4
The embodiment performs test verification on the blood sugar stabilizing efficacy of the pregnant and lying-in women milk powder.
The test method comprises the following steps: human test methods according to WS/T652-2019 methods for determining glycemic index of foods.
12 Qualified volunteers are screened, the ages are 18-60 years, the body mass index is in the normal range of 18.5kg/m 2-24.0kg/m2, the volunteers can tolerate the fasting state for at least 10 hours, no history of diabetes, impaired glucose tolerance, other metabolic diseases, digestive system diseases and the like are avoided, no allergic and intolerance history is caused to products of the invention, and no nutrient supplement and any medicine affecting the glucose tolerance are taken in 3 months.
Performing test food measurement for 3 times, wherein each measurement interval exceeds 72 hours, the test food measurement of the food to be measured is arranged between two reference foods, and the regular work and rest of the subjects in the first three days are measured, so that the food is normally eaten; measuring the dinner of the previous day to avoid high dietary fiber and high confectionery, and starting fasted before 22:00; during the measurement, when the test is started after the test subject sits still for 10min on the morning, 2 fasting blood samples are collected at intervals of 5min, a reference food of glucose solution formed by dissolving 20g of glucose in 250mL of purified water at 45 ℃ is taken, and a test food of milk powder solution formed by dissolving the pregnant and lying-in women milk powder prepared in example 1 in 250mL of purified water at 45 ℃ is taken, wherein the blood samples are collected 15min, 30min, 45min, 60min, 90min and 120min after the start of the intake. After drawing a blood glucose response curve, calculating the GI value and the GL value of the product according to the following formula:
The calculation of the GI value of the food to be tested is shown in the formulas (1) and (2):
Gin—the GI value obtained from the subject individual;
n—the number of subjects who eventually included the calculation of the GI value of the food to be tested;
GI-GI value of food to be measured
The method for calculating the GL value of the food to be detected comprises the following steps:
GL=C×GI/100
GL-blood glucose load value;
GI-the GI value of the food to be measured;
C-available carbohydrate content per unit mass of food in grams (g).
The test results of the 12 subjects are shown in Table 4.
TABLE 4 Table 4
According to the GI value results in Table 1, the available carbohydrate content per unit mass of food in the product of the invention was 46.8g; the test results show that the GI value is 16.64, the GL value is 7.79, and the GI is less than or equal to 55 and GL is less than 10 according to the food GI and GL grading judgment standard, so that the pregnant and lying-in woman milk powder prepared in the example 1 has the effect of stabilizing blood sugar.
Comparative example 1
This comparative example provides a formula which differs from example 1 only in that the raw milk is a non-organic A2 raw milk, the mineral source is an inorganic mineral, and white granulated sugar is added to the formula.
Specifically, the comparative formula milk powder comprises the following components in parts by weight:
57 parts of common raw milk calculated by dry matter,
22 Parts of whey protein powder,
10 Parts of maltodextrin,
4.5 Parts of white granulated sugar,
4.5 Parts of fructo-oligosaccharide,
1 Part of calcium carbonate,
0.6 Part of compound nutrition enhancer,
0.6 Part of docosahexaenoic acid grease powder.
The preparation method of the formula milk powder of the comparative example is the same as that of example 1.
Example 5
This example provides a follow-up evaluation of the digestive comfort of the maternal formula prepared in example 1 and the formula provided in comparative example 1.
30 Pregnant and parturient volunteers were recruited, the physical condition of the volunteers was recorded in detail prior to the trial, and all volunteers had no history of intestinal diseases, including gastric reflux, inflammatory bowel disease, no milk allergy symptoms, no use of drugs that might affect digestive function, etc.
The enrolled 30 volunteers were provided with both the product of comparative example 1 and the product of example 1, and were twice daily with 35g of milk powder supplemented with 200ml of water to prepare the formula of example 1 and comparative example 1, which was evaluated for comfort after a two month period and the results are shown in table 5.
TABLE 5
From the statistics of Table 5, it can be seen that, in the case that 27 volunteers had no abdominal distension, diarrhea and constipation in 30 volunteers, there was a significant improvement compared with the product of comparative example 1, in the period of 2 months when the comparative example product and the maternal formula of the present invention were taken together. The milk powder for pregnant and lying-in women, which is disclosed by the invention, is continuously taken, and the comfort of the volunteers of the pregnant and lying-in women to the product is obviously improved: symptoms affecting the comfort of the product such as abdominal distension, diarrhea and constipation are rarely generated.
The A2-beta casein contained in the pregnant and lying-in woman milk powder can achieve the aim of regulating gastrointestinal health, and can improve intestinal digestion comfort of female lactose intolerant patients; the alpha-lactalbumin and the oligosaccharide can synergistically promote the proliferation of bifidobacteria in the intestinal tract, improve the health of the intestinal tract and build a good intestinal environment; meanwhile, the alpha-lactalbumin has sites for combining divalent metal ions such as calcium, iron, zinc, manganese and the like, and the beta-casein is cooperated to promote the absorption of the metal ions such as calcium, zinc and the like. The iron and zinc supplement of the invention has higher solubility of ferrous gluconate than ferrous sulfate, and the bioavailability of zinc gluconate is higher than that of zinc sulfate, thus being more beneficial to the digestion and absorption of human bodies, particularly pregnant and lying-in women with weak gastrointestinal digestion function; vitamin K 2 can improve the sensitivity of insulin and has potential effect in preventing and/or treating diabetes, vitamin D can stimulate vitamin K 2 -dependent protein synthesis in calcium metabolism, and when the vitamin D is taken, the demand of human body for vitamin K 2 can be correspondingly increased, and the synergistic effect of vitamin D and vitamin K can maintain bone health. The synthesized folic acid is required to be metabolized in a human body by 4 steps and is converted into the 5-methyltetrahydrofolate with biological activity, and then the 5-methyltetrahydrofolate is absorbed by the human body, and according to statistics, more than 70% of people in China have MTHFR gene defects (risk of metabolic disorder of the synthesized folic acid), so that the risk is far from the pregnant and lying-in women, and the health of the pregnant and lying-in women is influenced, and researches show that if too much folic acid is added, a large amount of unabsorbed folic acid enters blood, the influence of the folic acid on the health exists for a long time, and the added 6S-5-methyltetrahydrofolate is not metabolized and is directly absorbed. The nutrient such as A2β -casein, organic minerals, active folic acid and the like in the formula milk powder for pregnant and lying-in women provided by the invention has the characteristics of strong absorbability and the like, can assist the pregnant and lying-in women to reasonably absorb the required nutrient substances, and is particularly suitable for being eaten by pregnant women, pregnant women and postpartum women suffering from gestational diabetes mellitus, and having weak intestinal functions and high requirements on digestion and absorption of the nutrient substances.

Claims (7)

1. The pregnant and lying-in woman formula milk powder for promoting digestion comfort and stabilizing blood sugar is characterized by comprising the following raw material components in parts by weight: 50-85 parts of A2 type defatted raw milk, 1-6 parts of galacto-oligosaccharide, 1-6 parts of fructo-oligosaccharide, 0.2-0.6 part of phospholipid, 0.6-1.0 part of compound nutrition enhancer, 0.5-1.5 parts of docosahexaenoic acid grease powder, 0.03-0.2 part of N-acetylneuraminic acid and 0.04-0.08 part of compound probiotic powder;
The compound nutrition enhancer comprises the following components in parts by weight: 60-80 parts of compound vitamins, 20-40 parts of compound minerals and 1-5 parts of lactose; the compound vitamin comprises the following components in percentage by weight: 0.55-0.85% of vitamin A, 0.4-0.5% of vitamin D, 3.5-4.8% of vitamin E, 3.00-4.00% of vitamin K 2 , 0.10-0.15% of vitamin B 1 , 1.00-1.50% of vitamin B 2 , 3.00-3.80% of vitamin B 6 , 0.05-0.15% of 6S-5-methyltetrahydrofolate calcium, 0.02-0.08% of vitamin B 12 , 19.00-22.00% of vitamin C, 20.10-28.50% of choline, 4.00-5.50% of L-carnitine, 4.20-5.50% of taurine and the balance lactose; the compound mineral comprises the following components in percentage by weight: 15.00-25.00% of ferrous gluconate, 6.50-8.70% of zinc gluconate, 0.75-1.25% of sodium selenite and the balance of lactose.
2. The maternal formula for promoting digestion comfort and stabilizing blood sugar according to claim 1, which is characterized by comprising the following raw material components in parts by weight: 60-80 parts of A2 type skim milk, 2-3.5 parts of galacto-oligosaccharide, 2-5.5 parts of fructo-oligosaccharide, 0.2-0.5 part of phospholipid, 0.6-0.9 part of compound nutrition enhancer, 0.8-1.5 parts of docosahexaenoic acid grease powder, 0.05-0.18 part of N-acetylneuraminic acid and 0.05-0.06 part of compound probiotic powder.
3. The maternal formula for promoting digestion comfort and stabilizing blood sugar according to claim 1, which is characterized by comprising the following raw material components in parts by weight: 65-80 parts of A2 type skim milk, 2.5-3.5 parts of galacto-oligosaccharides, 3-5.5 parts of fructo-oligosaccharides, 0.3-0.5 part of phospholipids, 0.7-0.9 part of compound nutrition enhancers, 0.8-1.2 parts of docosahexaenoic acid grease powder, 0.05-0.18 part of N-acetylneuraminic acid and 0.05-0.06 part of compound probiotics powder based on dry matter.
4. The pregnant and lying-in woman formula milk powder for promoting digestion comfort and stabilizing blood sugar according to claim 1, wherein the composite probiotic powder is composed of at least two of bifidobacterium animalis subspecies Bb-12, bifidobacterium animalis subspecies HN019, bifidobacterium animalis subspecies Bi-07 and bifidobacterium longum subspecies Bb536 in any ratio.
5. A method for preparing maternal formula milk powder for promoting digestion comfort and stabilizing blood glucose according to any one of claims 1-4, characterized by comprising the following steps:
step one, screening and collecting A2 raw cow milk:
selecting pure breed A2 dairy cows and carrying out clustered breeding and cultivation and collecting A2 raw dairy cows by carrying out gene identification screening on large-scale pasture dairy cows;
Step two, degreasing the raw milk of the A2:
filtering, cooling and storing the A2 raw milk obtained in the step one, degreasing to obtain skimmed milk, homogenizing the skimmed milk after degerming and separating, and then pasteurizing to obtain pasteurized milk, and cooling and storing;
Step three, batching:
Adding other auxiliary materials except the docosahexaenoic acid grease powder, the N-acetylneuraminic acid, the compound nutrition enhancer and the compound probiotic powder into a vacuum mixer according to the formula weight parts to be mixed; dissolving the compound nutrition enhancer according to the water-powder mass ratio required by the process at the dissolving temperature, adding the dissolved compound nutrition enhancer into a vacuum mixer, and mixing the dissolved compound nutrition enhancer with other auxiliary materials and pasteurized milk obtained in the step two to obtain the prepared milk;
step four, preparing a semi-finished product of milk powder:
homogenizing the prepared milk obtained in the step three, removing most of water in the prepared milk through vacuum sterilization and concentration to obtain concentrated milk, and performing spray drying and fluidized bed cooling on the obtained concentrated milk to obtain a milk powder semi-finished product;
Step five, preparing a milk powder finished product:
premixing the docosahexaenoic acid grease powder, the N-acetylneuraminic acid and the compound probiotic powder with part of the semi-finished milk powder obtained in the step four according to the formula requirement in parts by weight to obtain a premix, fully mixing the rest semi-finished milk powder with the premix, and packaging to obtain the finished pregnant and lying-in woman formula milk powder.
6. The method for preparing pregnant and parturient women's formula milk powder for promoting digestion comfort and stabilizing blood sugar according to claim 5, wherein the impurity degree of the A2 raw milk obtained by the filtering in the second step is less than 0.25ppm; step two, the pasteurization temperature is 80-85 ℃ and the sterilization time is 15s; in the third step, the mass ratio of water to powder is not lower than 8:1 when the compound nutrition enhancer is dissolved, and the dissolution temperature is 30-50 ℃.
7. The method for preparing pregnant and lying-in woman formula milk powder for promoting digestion comfort and stabilizing blood sugar according to claim 5 or 6, wherein in the fourth step, the homogenizing pressure is 160-210 bar, the sterilization temperature of vacuum sterilization and concentration is 85-98 ℃, the moisture of the prepared milk removed by concentration is 60%, and the density of the obtained concentrated milk is 1100-1200 kg/m 3; the pressure of the high-pressure pump for spray drying is 150-250 bar, the air inlet temperature is 160-200 ℃, the air exhaust temperature is 65-90 ℃, and the fluidized bed cooling is to cool the finished milk powder to 10-30 ℃; and fifthly, premixing for 5-10 min, wherein the mixing time is 5-10 min, the oxygen content in the package of the packaged bagged product is lower than 2.5%, and the oxygen content in the package of the canned product is lower than 5.0%.
CN202211429648.1A 2022-11-15 2022-11-15 Pregnant and lying-in woman formula milk powder capable of promoting digestion comfort and stabilizing blood sugar and preparation method thereof Active CN115708530B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202211429648.1A CN115708530B (en) 2022-11-15 2022-11-15 Pregnant and lying-in woman formula milk powder capable of promoting digestion comfort and stabilizing blood sugar and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202211429648.1A CN115708530B (en) 2022-11-15 2022-11-15 Pregnant and lying-in woman formula milk powder capable of promoting digestion comfort and stabilizing blood sugar and preparation method thereof

Publications (2)

Publication Number Publication Date
CN115708530A CN115708530A (en) 2023-02-24
CN115708530B true CN115708530B (en) 2024-08-09

Family

ID=85233432

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202211429648.1A Active CN115708530B (en) 2022-11-15 2022-11-15 Pregnant and lying-in woman formula milk powder capable of promoting digestion comfort and stabilizing blood sugar and preparation method thereof

Country Status (1)

Country Link
CN (1) CN115708530B (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105407971A (en) * 2013-05-31 2016-03-16 艾尔牛奶有限公司 Beta-casein A2 and prevention of inflammation of the bowel
CN114304274A (en) * 2021-11-23 2022-04-12 黑龙江爱维仕乳品有限公司 Formula milk powder for pregnant and lying-in women at different stages and preparation method

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003503038A (en) * 1999-06-29 2003-01-28 ザ・ニュージーランド・ミルク・インスティチュート・リミテッド Preventive supplements based on milk
CN103609748A (en) * 2013-12-10 2014-03-05 内蒙古伊利实业集团股份有限公司 Hypoglycaemic milk powder for pregnant women and preparation method thereof
NL2019906B1 (en) * 2017-11-14 2019-05-20 Ausnutria Hyproca B V Composition comprising a2 b-casein and a vegetable fat mixture
CN110250288A (en) * 2019-07-23 2019-09-20 宁波特壹食品有限公司 Nursing period formula milk and preparation method thereof
CN110810515A (en) * 2019-11-25 2020-02-21 海南国健高科技乳业有限公司 Formula milk powder for pregnant and lying-in women and preparation method thereof
CN113068747A (en) * 2020-03-24 2021-07-06 北京三元食品股份有限公司 Pregnant and lying-in woman formula milk powder for promoting health of pregnant and lying-in women and infants
CN111602719A (en) * 2020-05-11 2020-09-01 呼伦贝尔双娃乳业有限公司 Organic formula milk powder for pregnant and lying-in women
CN113678897A (en) * 2021-08-27 2021-11-23 庞海丰 Formula milk powder for promoting nutrient absorption of pregnant and lying-in women and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105407971A (en) * 2013-05-31 2016-03-16 艾尔牛奶有限公司 Beta-casein A2 and prevention of inflammation of the bowel
CN114304274A (en) * 2021-11-23 2022-04-12 黑龙江爱维仕乳品有限公司 Formula milk powder for pregnant and lying-in women at different stages and preparation method

Also Published As

Publication number Publication date
CN115708530A (en) 2023-02-24

Similar Documents

Publication Publication Date Title
ES2605453T3 (en) Maternal diet supplement
RU2457836C2 (en) Additive to maternal diet
Sandström et al. Effects of α-lactalbumin–enriched formula containing different concentrations of glycomacropeptide on infant nutrition
US20050208035A1 (en) Nutritional composition for treating an immune condition
CN110754530A (en) Formula milk powder capable of effectively promoting height development of children and production method thereof
JP5864676B2 (en) Composition for preventing or treating anemia
CN104920618A (en) Formula goat milk powder for pregnant and lying-in woman
CN109169916A (en) A kind of puerpera's nutriment and its production technology
CN107912535A (en) A kind of bovine colostrum composite powder and preparation method thereof
CN111067104A (en) Composite probiotic infant formula milk powder and preparation method thereof
CN112106836A (en) Yak milk powder for middle-aged and old people and preparation method thereof
CN111587923A (en) An infant formula containing sialic acid and its preparation method
EA011075B1 (en) Dry powdered milk formula
CN107373487A (en) A kind of ferrous bisglycinate chelate electuary
CN115708530B (en) Pregnant and lying-in woman formula milk powder capable of promoting digestion comfort and stabilizing blood sugar and preparation method thereof
CN106418067A (en) Health beverage capable of replenishing physical power and relieving fatigue
EP2956015B1 (en) Method for restoring and/or maintaining a positive net protein balance in a child
CN113973923A (en) Goat milk-based total nutrient formula powder for special medical purposes and preparation method thereof
Committee on Nutrition The use of whole cow's milk in infancy
RU2341276C1 (en) Method of gastrointestinal disturbance prevention in newborn calfs
Hamed et al. Overview of the Updates in Nutrient Profiles, Types, Indications and Side Effects of Infant Formula
CN108935701A (en) A kind of preparation method and application improving the goat milk powder of immunity, goat milk powder
JP3247786B2 (en) Foods Highly Containing β-Casein
CN115702653A (en) Sleep-assisting middle-aged and old-aged modified goat milk powder and preparation method thereof
Atomei et al. Nutrition in pregnancy–impact on anaemia in pregnant women

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant