CN115702916A - Personalized traditional Chinese medicine composition with alopecia prevention effect, traditional Chinese medicine preparation and providing method thereof - Google Patents
Personalized traditional Chinese medicine composition with alopecia prevention effect, traditional Chinese medicine preparation and providing method thereof Download PDFInfo
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Abstract
The invention relates to a personalized traditional Chinese medicine composition with an anti-alopecia effect, a traditional Chinese medicine preparation and a providing method thereof. The traditional Chinese medicine composition comprises four components mixed according to a certain proportion: the component one: 10-30 parts of raw cacumen biotae, 5-25 parts of fried gardenia, 1-20 parts of coptis chinensis, 1-30 parts of mint and 5-25 parts of mulberry leaves; and (2) component two: 20-40 parts of polygonum multiflorum, 10-30 parts of black sesame, 10-30 parts of eclipta alba, 10-30 parts of glossy privet fruit and 5-25 parts of parasitic loranthus; the component III is as follows: 5-25 parts of caulis spatholobi and 10-30 parts of moutan bark; 5-25 parts of dried rehmannia root; the component four is as follows: 5-25 parts of divaricate saposhnikovia root, 5-25 parts of tribulus terrestris and 20 parts of Chinese pine node. The combination proportion of the four components can be unfixed, a user can provide individual information (filling in a questionnaire and the like), and the personalized combination proportion of the four components is obtained through the modes of program calculation and the like, so that the personalized Chinese medicinal preparation for the user is provided. The traditional Chinese medicine composition is safe and effective for external use, can effectively reduce alopecia, has certain effects of controlling oil, removing dandruff, relieving red swelling and itching of scalp, and strengthening and toughening hair, and comprehensively improves scalp health.
Description
Technical Field
The invention belongs to the field of daily chemicals, and particularly relates to a personalized traditional Chinese medicine composition with an anti-hair loss effect, a traditional Chinese medicine preparation and a providing method thereof.
Background
Alopecia is a common puzzle faced by young and middle-aged people in the current society. The etiology of this disease is not completely clear, and most of the diseases are related to genetic factors, excessive secretion of male hormones, emotional stress, sleep, endocrine and other factors. The patient is often brought with great mental stress and psychological burden, and with the improvement of the living standard of people, the requirement for the treatment of the disease is more urgent.
There is no uniformly accepted high cure rate therapy for alopecia, and the currently commonly used therapeutic means include: hair transplant, western medicine preparation and Chinese herbal medicine preparation. Hair transplantation belongs to invasive surgical treatment and is high in price; western medicines such as oral finasteride and external minoxidil have obvious side effects such as sexual dysfunction, catarrhal period and the like, and have limited curative effect and are difficult to be widely used.
The traditional Chinese medicine has great advantages in the field of treating alopecia. According to the literature and the published patents, the technical schemes of the Chinese herbal medicine preparation related to the field of alopecia prevention are numerous, the Chinese herbal medicine anti-alopecia products sold on the market are endless, and the inventor discovers that no anti-alopecia preparation which is well recognized and effective by the public and has good public praise exists through market research and user research. The inventor discovers that the traditional Chinese medicine has a good curative effect basis for treating the alopecia through long-term clinical data conclusion analysis, but the traditional Chinese medicine gives attention to syndrome differentiation and treatment, and the premise of obtaining the best curative effect is to accurately differentiate the syndrome according to the constitution of each person. However, all the existing anti-hair loss products have the problems of similar composition thought and serious technical homogenization. A more sophisticated and perfect traditional Chinese medicine formula is not suitable for all people. The alopecia has different causes, constitutions and sexes and ages, and a product with a fixed formula is difficult to achieve good curative effect for all people.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition and a traditional Chinese medicine preparation for preventing alopecia, so that the alopecia problem of wide middle-aged and young people is relieved, and the traditional Chinese medicine composition and the traditional Chinese medicine preparation have certain effects of controlling oil, removing dandruff, relieving red swelling and itching of scalp, strengthening and toughness hair and preventing hair from being broken, and comprehensively improve scalp health.
In order to achieve the purpose, the invention adopts the following technical scheme:
a personalized traditional Chinese medicine composition with the effect of preventing alopecia is characterized by comprising 4 types of components which are mixed according to a certain proportion:
component one (the main effect is clearing heat and is used for treating damp-heat): 10-30 parts of raw cacumen biotae, 5-25 parts of fried gardenia, 1-20 parts of coptis chinensis, 1-30 parts of mint and 5-25 parts of mulberry leaves;
and the second component (the main efficacy is tonifying liver and kidney and is used for treating liver and kidney deficiency): 20-40 parts of polygonum multiflorum, 10-30 parts of black sesame, 10-30 parts of eclipta alba, 10-30 parts of glossy privet fruit and 5-25 parts of parasitic loranthus;
and the third component (the main effects of cooling blood and enriching blood and used for treating blood heat and blood deficiency): 5-25 parts of caulis spatholobi and 10-30 parts of moutan bark; 5-25 parts of dried rehmannia root;
the fourth component (the main effect is dispelling wind and is used for treating wind evil preponderance): 5-25 parts of divaricate saposhnikovia root, 5-25 parts of tribulus terrestris and 20 parts of pinus tabulaeformis.
Preferably, the traditional Chinese medicine composition comprises the following 4 types of components:
the component one: 20 parts of raw cacumen biotae, 15 parts of fried gardenia, 10 parts of coptis chinensis, 10 parts of mint and 15 parts of mulberry leaves;
and (2) component two: 30 parts of polygonum multiflorum, 20 parts of black sesame, 20 parts of eclipta alba, 20 parts of glossy privet fruit and 15 parts of parasitic loranthus;
the third component: 15 parts of caulis spatholobi and 20 parts of moutan bark; 15 parts of dried rehmannia root;
the component four is as follows: 15 parts of divaricate saposhnikovia root, 15 parts of tribulus terrestris and 20 parts of Chinese pine node.
Furthermore, the combination proportion of the components of the traditional Chinese medicine composition can be unfixed, and the traditional Chinese medicine composition is combined in a personalized way according to the requirements of users.
Aiming at the characteristics of alopecia, the traditional Chinese medicine composition selects 4 types of traditional Chinese medicines with different functions, and is combined according to personalized proportion. The traditional Chinese medicine considers that the pathogenic factors of the alopecia are wind, dampness and heat, the internal factors are caused by kidney qi deficiency and qi and blood deficiency, and the clinical common symptoms of the alopecia are damp-heat accumulation, liver and kidney deficiency, blood heat and wind dryness and blood deficiency and wind dryness, and four types of traditional Chinese medicines are combined according to the formula.
The components have the effects of clearing heat, and raw cacumen biotae is selected to clear heat, cool blood, strengthen hair and prevent alopecia, fried gardenia and coptis root are selected to clear heat and dry dampness, mulberry leaves are selected to clear liver and disperse wind, mint is selected to disperse wind and clear heat, and the five medicines are organically combined to jointly enhance the heat-clearing power and are different from each other. The raw arborvitae tops are the essential medicine for preventing alopecia and can cool blood; gardenia and coptis root are thick in taste, act downwards, clear heat evil of triple energizer, and are bitter, cold and dry; sang Ye is good at clearing liver fire and lung fire and moistening dryness; minty is light in nature, prefers to walk outside, acts upwards, and is good at refreshing head and eyes, inducing resuscitation and refreshing, cool and refreshing. Five medicines are mutually reinforced, so that the patient is swerved and swollen if the medicine is too much, and the patient is afraid to be too much if the medicine is too little.
The two components are specially used for tonifying liver and kidney, the polygonum multiflorum is used for tonifying kidney, benefiting liver and nourishing blood, the eclipta alba and the glossy privet fruit are used for tonifying liver and kidney yin, the black sesame is used for nourishing liver and kidney and blacking hair, and the loranthus parasiticus is used for tonifying liver and kidney and growing beard and eyebrow. The five medicines are organically combined to strengthen the force of tonifying the liver and the kidney together and are different from each other. The fleece-flower root is the essential medicine for preventing alopecia and treating early graying of hair, and has astringent and astringent properties and the effects of benefiting essence and blood; the eclipta alba and the glossy privet fruit jointly form a famous medicine, namely a second-half pill which is sweet and cool in nature, can nourish liver and kidney, and can cool blood and clear deficiency heat; the black sesame and the mulberry leaves jointly form a famous medicine mulberry hemp pill which is mild in property, can keep healthy and tonify and can blacken hair; sang Ji Sheng is bitter in taste and can tonify liver and kidney, dispel wind-damp and nourish blood. Each herb is selected to maximize its function, and the primary action point and the secondary action point are considered.
The components have three functions of specially cooling and replenishing blood, and the caulis spatholobi is selected to activate and replenish blood, the radix rehmanniae is used for cooling blood and replenishing essence and blood, and the cortex moutan is used for activating and cooling blood; the three medicines are mutually reinforced and complementary, and the caulis spatholobi is a rattan medicine which can tonify blood and promote blood circulation, remove blood stasis and generate new blood; radix rehmanniae is thick and heavy in flavor, and can nourish liver and kidney, benefit essence and produce blood while cooling blood; moutan bark, cortex moutan cools blood, and is also the key herb for clearing deficiency heat; the three medicines are organically combined to cool and enrich the blood together, and the power of invigorating the circulation of blood, nourishing the liver and the kidney and clearing heat is increased, so that the medicine selection is precise and appropriate, and each medicine has great profound meaning.
The four components are specially used for dispelling wind, and the divaricate saposhnikovia root for dispelling wind and eliminating dampness, the tribulus terrestris for calming the liver for dispelling wind and the Chinese pine node for dispelling wind and eliminating dampness are selected. The three medicines are like a stable triangle, and have the effect of dispelling wind but have different emphasis. Fang Feng wanders outward, the first essential herb to dispel wind and also can dispel dampness; tribulus terrestris, which is located in the interior and has the actions of calming the liver, dispelling wind, and refreshing the head and eyes; pinus sylvestris is good at moving through joints of muscles and bones and entering liver and kidney meridians to dispel wind-damp. The three herbs are selected to have the combination of essence and exterior, interior and joint in consideration, so as to achieve the best effect of dispelling wind.
The four components are combined to respectively correspond to four symptoms of alopecia: the traditional Chinese medicine composition has the effects of strengthening hair, preventing alopecia, removing dandruff, relieving itching, strengthening and blackening hair and the like under the combined action of internal damp-heat, liver and kidney deficiency, blood deficiency and wind dryness, internal liver and kidney deficiency and blood nourishing deficiency, and external damp-heat and wind evil dispelling. The organic combination of the four components and the selection of each medicine are not simple combination of various medicines, but the medicines have functional support and interaction with each other, seek for maximization of function, and take into account the main action point and the secondary action point. The specific constitution of each different person is different, and the degrees of damp-heat, liver and kidney deficiency, blood heat, blood deficiency and wind dryness are different on each person, so that the proportion of each component needs to be flexibly matched, the medicine is more accurate to use, and targeted and individualized treatment can be performed better, thereby achieving the best curative effect.
The invention also provides a personalized traditional Chinese medicine preparation with the alopecia prevention effect, which is prepared from the traditional Chinese medicine composition and auxiliary materials acceptable in the field of daily use chemicals.
Further, the preparation method of the traditional Chinese medicine preparation comprises the following steps: the four components are respectively mixed and then crushed, 40% -90% ethanol solution with the weight 10-20 times of the weight of each component is respectively added, the components are sealed and soaked for 2-3 months at normal temperature, dregs of a decoction are filtered to remove dregs of a decoction, supernate is taken out, the supernate is continuously filtered twice in a filter screen to obtain filtrate, various preparation components are obtained, the components are respectively sealed and stored, and the components are mixed according to individual proportion according to individual conditions of users.
When the traditional Chinese medicine preparation is applied, the using method is external application, and the traditional Chinese medicine preparation is applied to hair or scalp, or is added into auxiliary materials according to the proportion of 10-100 percent by weight to be prepared into shampoo, spray, lotion, ointment, oil agent, cream, cataplasm, liniment, film coating agent and the like.
The invention also provides a method for providing the personalized traditional Chinese medicine composition, which comprises the following steps: the user provides individual information, processes the user information to give the combination ratio among the preparation components, and mixes the preparation components in proportion, thereby providing the Chinese medicinal preparation individualized by the user. The mode of providing individual information by the user comprises answering questions, filling in a questionnaire, providing a photo and the like; the mode of processing the user information comprises program calculation according to the questionnaire score; the preparation components are mixed according to the proportion, and the mixing can be completed by a preparation provider or completed by a user.
The traditional Chinese medicine composition is convenient to use, safe and effective: 1. can obviously reduce alopecia and improve hair density grading; 2. the hair conditioner has the obvious effects of controlling oil, reducing dandruff, improving scalp itch, enabling hair to be shinier, tough and not easy to break and the like on the aspects of scalp health and hair quality improvement; 3. has certain function of promoting the new growth of hair; 4. the external application is safe, and adverse reactions and severe discomfort symptoms do not exist; 5. the effect of the personalized proportion of the traditional Chinese medicine composition is more optimized than that of the basic fixed proportion of the traditional Chinese medicine composition.
Detailed Description
In order to further illustrate the present invention, the following examples are provided to describe the personalized traditional Chinese medicine composition with anti-alopecia effect, the traditional Chinese medicine preparation and the providing method thereof in detail, but they should not be construed as limiting the scope of the present invention.
Example 1: specific providing method of personalized traditional Chinese medicine preparation
The personalized traditional Chinese medicine preparation has the main innovation point that the personalized medicine combination proportion can be generated according to different physiques of each person, so that each person can use the personalized anti-alopecia medicine which is tailored. The generation method of the combination ratio can be divided into 2 types: 1. the user fills in a well-formulated questionnaire, and the scores obtained by the four modules are calculated to obtain a proportion; 2. for mild constitutions without obvious bias, the formula 1:1:1: 1.
The 2 methods are described in detail below:
1.1 User self-filling questionnaire
The user fills in the questionnaire by himself, corresponding scores are filled in the score column to obtain the corresponding total scores of the four modules, and the total scores are divided by the full scores of the corresponding modules, and the proportion of the four component medicines is (module one total score/36): (Module two Total/44): (Module III Total/28): (Module four Total points/28). If the resulting ratio figures carry decimal values, rounding can be used.
TABLE 1 alopecia syndrome-identifying self-filling questionnaire
Specific example 1: in a woman, 30 years old, with 4 months of hair loss, the hair density was graded to 4 (medium density, small visible scalps). The symptoms are characterized in that: the hair is oily, the scalp is itchy with red rash, dandruff is much, acne is grown, stool is sticky, and the hair is often decocted all night, poor in physical strength, large in menstrual flow and easy to be allergic. Syndrome differentiation is mainly based on damp-heat accompanied by blood heat and wind pathogen. After the questionnaire is filled, the four total points are 19 points, 7 points, 3 points and 8 points respectively, and the calculation proportion =19/36:7/44:3/28:8/28, rounded up, the user uses a ratio of 5:2:1:3.
specific example 2: zhao, male, age 38, baldness 1 year, with hair density graded at level 2 (sparse, easy to see scalp). The symptoms are characterized in that: the hair is thin, soft and easy to break, the hair is left on the bald part with thin, soft and short hair, the hair has little oil, the hair has no luster, much dandruff, hereditary baldness, brainwork, poor physical strength, often stays up all night, the face color is sallow, and the hair is easy to be allergic. Syndrome differentiation is mainly due to kidney deficiency, accompanied by damp-heat and wind-dryness. After the questionnaire is filled in, the four total points are respectively 8 points, 29 points, 7 points and 9 points, and the calculation proportion =8/36:29/44:7/28:9/28, rounded, the user uses the ratio 2:6:3:3.
1.2 Using the basic mixture ratio
The basic mixture ratio is suitable for most people, some users only show alopecia, other symptoms are not obvious, the constitution is mild and has no obvious deviation, and the traditional Chinese medicine composition can be directly used for 1:1:1: 1.
Example 2: clinical trial effect on preventing alopecia
The clinical research is carried out according to the related requirements of 'cosmetic anti-hair loss efficacy testing method' published by the national drug administration of 2021.
1. Study object
The qualified subjects are selected according to the selection and exclusion standards and divided into three groups randomly, namely a control group, a basic prescription drug group and a dialectical prescription drug group, wherein each group comprises 100 persons.
1.1 inclusion criteria: (1) a healthy male or female aged 18-60 years; (2) the trouble of much hair loss or light-moderate hair thinning; (3) The body has no major diseases, and the secondary alopecia and the pathological alopecia are definitely diagnosed.
1.2 exclusion criteria: (1) pregnant or lactating women; (2) allergic to alcohol; (3) Those with severe allergic diseases or who are susceptible to allergy to Chinese herbs; (4) The damage or infection of scalp and face is not suitable for the patients.
2. Research method
2.1 grouping: subjects were randomized into three groups. (1) control group: using a commercially available anti-hair loss shampoo; (2) the basic prescription drug group: the traditional Chinese medicine preparation disclosed by the invention is prepared from the following basic components in parts by weight of 1. (3) dialectical prescription drug combination: the subjects answered the questionnaire and used the formulation of the invention in the personalized proportions based on the component proportions generated.
2.2 methods of use of the medicament: the method I comprises the following steps: mixing the traditional Chinese medicine preparation according to the volume of 1:6 proportion is added into shampoo and mixed evenly, and the mixture is used for washing hair each time, and is kept for 10min to be washed off after being fully kneaded; (2) method two: the Chinese medicinal preparation is filled into a spray bottle, and sprayed onto scalp for 1 time per day. The 2 application methods comprise a first application method for 50 percent of people in the basic prescription drug group and the syndrome differentiation prescription drug group, and a second application method for 50 percent of people.
2.3 test procedure: general data were collected from subjects prior to study initiation, including age, sex, current hair loss, current hair density grading, \8230;. The drug is continuously used for 8 weeks, and the evaluation is respectively carried out for 3 times at 4 weeks, 8 weeks and 12 weeks after the start (namely 4 weeks after the drug is stopped), the hair cannot be washed 48 hours before each evaluation, and the hair is not combed on the visit day. The evaluation indexes include hair loss count, hair density grading, self-use feeling evaluation, scalp health, hair quality and other improvement conditions.
(1) Counting the hair loss: the hair was combed with 60 combing and the amount of shed hair was counted. Combing 60 times (30 times for each left and right) at a constant speed according to the sequence from left front to left back and right front to right back.
(2) Hair Density assessment
Table 2 hair density rating table.
| Grading | Description of the invention |
| 0 | Without hair |
| 1 | Very sparse and clearly visible scalp |
| 2 | Sparseness and easy to see the scalp |
| 3 | Sparse and visible scalp |
| 4 | Medium densityVisible small amount of scalp |
| 5 | Dense, very little scalp visible |
| 6 | Dense, occult scalp |
| 7 | Very dense and the scalp is barely visible. |
3. Results of the study
The subjects were 21-56 years old, the 3 groups had an average age of 32.9-34.6 years old, the subjects were more female, and the subjects in the three groups had no significant difference in the age, sex, and hair density classifications.
Table 3 subject baseline data.
After the medicine is used for 4 weeks, the hair loss quantity of the basic prescription medicine group and the syndrome differentiation prescription medicine group can be obviously reduced and is obviously superior to that of a control group; the effect is more obvious after 8 weeks of use, and simultaneously, the alopecia prevention effect of the syndrome differentiation prescription drug combination is also obviously superior to that of the basic prescription drug combination. After stopping taking the medicine for 4 weeks, the number of the alopecia is basically the same as that of 8 weeks, which shows that the alopecia has no obvious rebound after stopping taking the medicine.
Table 4 hair loss counts before and after drug use.
| Control group (n = 100) | Basic prescription set (n = 100) | Dialectical prescription (n = 100) | P value | |
| Base line | 52.3±20.5 | 54.9±19.6 | 50.3±21.4 | ＞0.05 |
| Week 4 | 48.4±19.4 | 40.3±17.6 | 38.6±18.2 | ＜0.01 |
| Week 8 | 46.9±17.8 | 35.2±14.8 | 29.7±11.2 | ＜0.01 |
| Week 12 (week 4 after drug withdrawal) | 49.4±21.3 | 37.1±15.1 | 31.4±13.5 | ＜0.01 。 |
Subjects self-assessed post-use effects: 86% of subjects in the basic prescription group are fed back effectively, and 85% of subjects in the dialectical prescription group are evaluated to be effective, so that the evaluation is obviously superior to that of a control group. The syndrome differentiation formula medicines have good effect and obvious proportion (alopecia is more than 30%) higher than that of the basic formula medicines, which shows that although the two groups can effectively prevent alopecia, the syndrome differentiation formula medicines can maximize the curative effect.
TABLE 5 evaluation of subjects' self-use feeling.
| Control group (n = 100) | Basic prescription set (n = 100) | Dialectical prescription drug (n = 100) | P value | |
| Obvious effect (alopecia reduction is more than 50%) | 0 | 6（6%） | 14（14%） | ＜0.01 |
| Good effect (alopecia is reduced by 30-50%) | 8（8%） | 21（21%） | 26（26%） | ＜0.01 |
| Mildly effective (alopecia reduced by 10-30%) | 58（58%） | 59（59%） | 45（45%） | ＜0.01 |
| Nullification | 34（34%） | 14（14%） | 15（15%） | ＜0.01 |
The medicine has obvious effects of controlling oil, reducing dandruff, improving scalp itch, making hair more glossy, tough and not easy to break and the like in the aspects of scalp health and hair quality improvement, and has the effect of promoting new hair growth. Similarly, the dialectical prescription is slightly superior to the basic prescription, especially in controlling oil and improving scalp itching.
TABLE 6 improvement of scalp health, hair quality, etc.
| Control group (n = 100) | Basic prescription set (n = 100) | Dialectical prescription drug (n = 100) | P value | |
| Dandruff reduction | 14（14%） | 15（15%） | 19（19%） | ＜0.01 |
| Improvement of scalp itching | 16（16%） | 23（19%） | 32（32%） | ＜0.01 |
| Reduction of oil run-out | 13（13%） | 42（42%） | 56（56%） | ＜0.01 |
| The hair is shinier | 8（8%） | 12（12%） | 18（18%） | ＜0.01 |
| Strong and tough without easy breaking | 5（5%） | 24（24%） | 28（28%） | ＜0.01 |
| Has new hair | 7（7%） | 28（28%） | 32（32%） | ＜0.01 |
Adverse reactions occurred in 0 cases. Only a few cases reported mild discomfort with itching of the scalp, increased oil production, increased dandruff, possibly associated with initial use sensitive to alcohol or herbal ingredients, improper method of use, etc. All relieved after guiding the correct using method.
TABLE 7 adverse reactions and malaise symptoms.
| Control group (n = 100) | Basic prescription set (n = 100) | Dialectical prescription (n = 100) | |
| Adverse reaction | 0 | 0 | 0 |
| Slight discomfort | |||
| Itching of the scalp | 9（9%） | 3（3%） | 4（4%） |
| Increased oil production | 5（5%） | 2（2%） | 3（3%） |
| Increase of dandruff | 6（6%） | 0 | 1（1%） |
And (4) conclusion: the traditional Chinese medicine composition can obviously reduce the alopecia, improve the scalp health and the hair quality, and has the functions of controlling the oil, reducing the dandruff, relieving the itching, ensuring that the hair is shinier, tough and not easy to break, promoting the new hair; the effect of the personalized proportion of the traditional Chinese medicine composition is more optimized compared with the effect of the basic fixed proportion of the traditional Chinese medicine composition.
Example 3: typical examples are:
3.1 Shen Shi, male, age 32. Androgenetic alopecia was diagnosed for 3 months and hair density was graded as 2 (sparse, easy to see scalp). The symptoms are characterized in that: fine, soft and easy to break hair, white scalp, much hair loss, slight greasiness, frequent stay up and poor physical strength, mainly syndrome differentiation of kidney deficiency and wind-heat and blood heat, and the Chinese medicinal preparation with personalized proportion is used, and the proportion is 2:3:1:2, the kidney-tonifying component has higher proportion. After the hair loss is continuously used for 2 months, the hair loss is reduced by 30 to 40 percent, new hairs are visible, and the hair density is graded and improved to 3 grades.
3.2 Wei and Yi ren, female, 29 years old. About 50 hairs were lost per comb and the hair density was graded to 4 (medium density, small amount of scalp visible). The symptoms are characterized in that: scalp itching with erythra, greasy hair, hair washing every day, red tongue with yellow and greasy coating, constipation, syndrome differentiation of damp-heat and blood-heat as the main and wind evil. Using the traditional Chinese medicine preparation with personalized proportion, wherein the proportion of the traditional Chinese medicine preparation is 3:1:1:2, the heat-clearing component has higher proportion. After the shampoo is used for 1 week, the alopecia is reduced by 30 percent, the erythra disappears without pruritus, after the shampoo is continuously used for 2 months, the alopecia is reduced by 50 percent, the greasy hair is obviously improved, the hair can be washed every 2 to 3 days, and the hair density is graded and improved to 5 grades.
3.3 Wangzhi, female, 54 years old. White hair and significant hair loss, about 40 hairs were lost during each combing, and the hair density was graded as 4 (medium density, small amount of scalp visible). The symptoms are characterized in that: white hair is more, hair is dry, dandruff is more, facial complexion is dark and has spots, and skin is dry, and the syndrome differentiation is mainly blood deficiency and kidney deficiency, accompanied by wind evil and blood heat. Using the traditional Chinese medicine preparation with personalized proportion, wherein the proportion of the traditional Chinese medicine preparation is 1:3:3:2. the hair loss is reduced by 20 percent and the dandruff is reduced after 2 weeks of use, after 3 months of continuous use, the hair loss is reduced by 40 percent, the white hair is reduced, the new black hair is generated, and the hair quality is more tenacious and glossy than before.
3.4 Zhangzhi, female, age 35. Hair loss was evident with a hair density rating of 4 (medium density, small visible scalps). The symptoms are characterized in that: the hair loss is serious when the hair is washed every time, and other symptoms are not obvious. Belonging to mild constitutions, use 1:1:1:1, the alopecia is reduced by 30 percent after 2 weeks of use and 50 percent after 1 month of use.
Claims (10)
1. A personalized traditional Chinese medicine composition with alopecia prevention effect is characterized by comprising the following 4 types of components which are mixed according to a certain proportion:
the component one is as follows: 10-30 parts of raw cacumen biotae, 5-25 parts of fried gardenia, 1-20 parts of coptis chinensis, 1-30 parts of mint and 5-25 parts of mulberry leaves;
and (2) component two: 20-40 parts of polygonum multiflorum, 10-30 parts of black sesame, 10-30 parts of eclipta alba, 10-30 parts of glossy privet fruit and 5-25 parts of parasitic loranthus;
the component III is as follows: 5-25 parts of caulis spatholobi and 10-30 parts of moutan bark; 5-25 parts of radix rehmanniae;
the component four is as follows: 5-25 parts of divaricate saposhnikovia root, 5-25 parts of tribulus terrestris and 20 parts of Chinese pine node.
2. The traditional Chinese medicine composition with the alopecia preventing effect according to claim 1, which is characterized by comprising the following 4 types of components:
the component one is as follows: 20 parts of raw cacumen biotae, 15 parts of fried gardenia, 10 parts of coptis chinensis, 10 parts of mint and 15 parts of mulberry leaves;
and (2) component two: 30 parts of polygonum multiflorum, 20 parts of black sesame, 20 parts of eclipta alba, 20 parts of glossy privet fruit and 15 parts of parasitic loranthus;
the third component: 15 parts of caulis spatholobi and 20 parts of moutan bark; 15 parts of dried rehmannia root;
the component four is as follows: 15 parts of divaricate saposhnikovia root, 15 parts of tribulus terrestris and 20 parts of Chinese pine node.
3. The personalized traditional Chinese medicine composition with alopecia preventing effect according to claim 1, wherein the combination proportion of the components can be unfixed, and personalized combination is performed according to the requirements of users.
4. A personalized traditional Chinese medicine preparation with alopecia prevention effect is characterized by being prepared from the traditional Chinese medicine composition of any one of claims 1 to 3 and auxiliary materials acceptable in the field of daily use chemicals.
5. The personalized traditional Chinese medicine preparation with alopecia preventing effect according to claim 4, which is characterized in that the preparation method comprises the following steps: the preparation of claim 1-2, wherein the preparation comprises the components of the formula I, the components are mixed and crushed respectively, 10-20 times of 40% -90% ethanol solution is added respectively, the mixture is sealed and soaked for 2-3 months at normal temperature, the decoction dregs are filtered off, the supernatant is taken, the supernatant is filtered twice continuously in a filter screen to obtain filtrate, and the filtrate is sealed and stored respectively, and is mixed according to individual proportion according to individual conditions of users.
6. The personalized traditional Chinese medicine preparation with the alopecia preventing effect according to claim 4 or 5, which is an external preparation and is used on hair or scalp, or is added into auxiliary materials according to the proportion of 10-100% by weight to be prepared into shampoo, spray, lotion, ointment, oil, cream, cataplasm, liniment, film coating agent and the like.
7. A method for providing the personalized traditional Chinese medicine composition with alopecia prevention effect of claim 1, which is characterized by comprising the following steps: the user provides individual information, the user information is processed to give the combination proportion among the preparation components, and the preparation components are mixed according to the proportion, so that the individualized traditional Chinese medicine preparation is provided for the user.
8. The method as claimed in claim 7, wherein the manner of providing the individual information by the user includes answering questions, filling out a questionnaire, providing a photo, etc.
9. The method of claim 7, wherein the processing of the user information comprises performing a programmed calculation based on the questionnaire score.
10. The method of claim 7, wherein the mixing of the formulation components in the ratio is performed by the formulation provider or by the user.
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| CN106692442A (en) * | 2015-11-12 | 2017-05-24 | 张瑞芹 | Formula of traditional Chinese medicine for treating alopecia |
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| CN112791034A (en) * | 2021-01-12 | 2021-05-14 | 山东正基药业有限公司 | Anti-hair loss and hair-nourishing herbal shampoo and preparation method thereof |
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| CN101249146A (en) * | 2008-04-17 | 2008-08-27 | 房宁 | Hair-growing and hair care Chinese medicinal composition |
| CN106692442A (en) * | 2015-11-12 | 2017-05-24 | 张瑞芹 | Formula of traditional Chinese medicine for treating alopecia |
| CN110302280A (en) * | 2019-08-15 | 2019-10-08 | 北京科泰健业企业管理有限公司 | A kind of tuber of multiflower knotweed hair tonic health promoting liquid |
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