CN115697419A - 多聚体抗dr5结合分子与癌症疗法组合治疗癌症的用途 - Google Patents

多聚体抗dr5结合分子与癌症疗法组合治疗癌症的用途 Download PDF

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CN115697419A
CN115697419A CN202180031892.XA CN202180031892A CN115697419A CN 115697419 A CN115697419 A CN 115697419A CN 202180031892 A CN202180031892 A CN 202180031892A CN 115697419 A CN115697419 A CN 115697419A
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seq
cancer
antibody
binding
igm
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B·王
T·J·马修斯
E·W·休姆克
A·辛克莱
D·S·陈
B·A·基特
王玲
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IGM Biosciences Inc
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IGM Biosciences Inc
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CN202180031892.XA 2020-05-12 2021-05-12 多聚体抗dr5结合分子与癌症疗法组合治疗癌症的用途 Pending CN115697419A (zh)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US202063023635P 2020-05-12 2020-05-12
US63/023,635 2020-05-12
US202063078747P 2020-09-15 2020-09-15
US63/078,747 2020-09-15
US202063114990P 2020-11-17 2020-11-17
US63/114,990 2020-11-17
US202063131698P 2020-12-29 2020-12-29
US63/131,698 2020-12-29
US202163136156P 2021-01-11 2021-01-11
US63/136,156 2021-01-11
PCT/US2021/032078 WO2021231639A1 (en) 2020-05-12 2021-05-12 Use of a multimeric anti-dr5 binding molecule in combination with a cancer therapy for treating cancer

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CN115697419A true CN115697419A (zh) 2023-02-03

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CN202180031892.XA Pending CN115697419A (zh) 2020-05-12 2021-05-12 多聚体抗dr5结合分子与癌症疗法组合治疗癌症的用途

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US (1) US20230174660A1 (https=)
EP (1) EP4149553A4 (https=)
JP (1) JP2023526224A (https=)
KR (1) KR20230010221A (https=)
CN (1) CN115697419A (https=)
AU (1) AU2021271647A1 (https=)
BR (1) BR112022022145A2 (https=)
CA (1) CA3173919A1 (https=)
IL (1) IL297619A (https=)
MX (1) MX2022014259A (https=)
WO (1) WO2021231639A1 (https=)

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PL3560954T3 (pl) 2014-04-03 2021-12-13 Igm Biosciences, Inc. Zmodyfikowany łańcuch J
IL308212A (en) 2015-01-20 2024-01-01 Igm Biosciences Inc Tumor necrosis factor-α receptor binding molecules and their uses
WO2016154593A1 (en) 2015-03-25 2016-09-29 Igm Biosciences, Inc. Multi-valent hepatitis b virus antigen binding molecules and uses thereof
EP3355913B1 (en) 2015-09-30 2024-10-30 IGM Biosciences, Inc. Binding molecules with modified j-chain
EP3356401B1 (en) 2015-09-30 2020-06-24 IGM Biosciences, Inc. Binding molecules with modified j-chain
EP4277706A1 (en) * 2021-01-15 2023-11-22 Stichting Het Nederlands Kanker Instituut- Antoni van Leeuwenhoek Ziekenhuis Inducers of senescence, in combination with a selective death receptor 5 (dr5) agonist, for use in a method of treating cancer
TW202410919A (zh) * 2022-05-23 2024-03-16 美商英伊布里克斯公司 Dr5促效劑與iap拮抗劑之組合療法
WO2024148339A1 (en) * 2023-01-06 2024-07-11 Igm Biosciences, Inc. Use of a multimeric anti-dr5 antibody for treating cancer

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US20090317369A1 (en) * 2008-06-09 2009-12-24 Toru Hosoda Compositions comprising cardiac stem cells overexpressing specific micrornas and methods of their use in repairing damaged myocardium
CN107207601A (zh) * 2015-01-20 2017-09-26 Igm生物科学股份有限公司 肿瘤坏死因子(tnf)超家族受体结合分子及其应用
CN109476737A (zh) * 2015-12-01 2019-03-15 根马布有限公司 抗dr5抗体及其使用方法
WO2019165340A1 (en) * 2018-02-26 2019-08-29 Igm Biosciences, Inc. Use of a multimeric anti-dr5 binding molecule in combination with a chemotherapeutic agent for treating cancer
WO2019169314A1 (en) * 2018-03-01 2019-09-06 Igm Biosciences, Inc. IgM Fc AND J-CHAIN MUTATIONS THAT AFFECT IgM SERUM HALF-LIFE

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KR100847010B1 (ko) * 2006-07-05 2008-07-17 아주대학교산학협력단 세포사멸 수용체 5 (ｄｒ5)에 특이적으로 결합하는 항체 및이를 포함하는 암 예방 또는 치료용 조성물

Patent Citations (6)

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WO2008066854A2 (en) * 2006-11-28 2008-06-05 Novartis Ag Methods and compositions for inducing apoptosis in cancer cells
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